The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed because of a cast error
Error code: DatasetGenerationCastError
Exception: DatasetGenerationCastError
Message: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 3 new columns ({'SMILES', 'IDType', 'ID'}) and 7 missing columns ({'NumActiveCompounds', 'Description', 'URL', 'Reference', 'Paper Title', 'Assay Name', 'AID_confirmatory'}).
This happened while the csv dataset builder was generating data using
hf://datasets/maomlab/ChAFF/data/Absorbance.csv (at revision da0d7cd86fa09912e506f0889c911408061b0697)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback: Traceback (most recent call last):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
writer.write_table(table)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/arrow_writer.py", line 644, in write_table
pa_table = table_cast(pa_table, self._schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2272, in table_cast
return cast_table_to_schema(table, schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
raise CastError(
datasets.table.CastError: Couldn't cast
Type: string
DatasetName: double
AID: int64
ID: int64
IDType: string
SMILES: string
-- schema metadata --
pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 921
to
{'Type': Value('string'), 'DatasetName': Value('string'), 'AID': Value('float64'), 'AID_confirmatory': Value('float64'), 'NumActiveCompounds': Value('int64'), 'Paper Title': Value('string'), 'Reference': Value('string'), 'URL': Value('string'), 'Assay Name': Value('string'), 'Description': Value('string')}
because column names don't match
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1456, in compute_config_parquet_and_info_response
parquet_operations = convert_to_parquet(builder)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1055, in convert_to_parquet
builder.download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 894, in download_and_prepare
self._download_and_prepare(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 970, in _download_and_prepare
self._prepare_split(split_generator, **prepare_split_kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1702, in _prepare_split
for job_id, done, content in self._prepare_split_single(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
raise DatasetGenerationCastError.from_cast_error(
datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 3 new columns ({'SMILES', 'IDType', 'ID'}) and 7 missing columns ({'NumActiveCompounds', 'Description', 'URL', 'Reference', 'Paper Title', 'Assay Name', 'AID_confirmatory'}).
This happened while the csv dataset builder was generating data using
hf://datasets/maomlab/ChAFF/data/Absorbance.csv (at revision da0d7cd86fa09912e506f0889c911408061b0697)
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
Type string | DatasetName null | AID float64 | AID_confirmatory null | NumActiveCompounds int64 | Paper Title string | Reference string | URL null | Assay Name string | Description string |
|---|---|---|---|---|---|---|---|---|---|
Absorbance | null | 632 | null | 43 | A Novel Class of Small Molecule Inhibitors of Hsp90 | (Yi, 2008, 10.1021/cb800162x) | null | Confirmation Concentration-Response Assay and Counterscreen for Disrupters of an Hsp90 Co-Chaperone Interaction | Interference compounds have a score of 10 |
Absorbance | null | 1,641 | null | 92 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | TR-FRET counterscreen for FAK inhibitors: dose-response biochemical high throughput screening assay to identify inhibitors of Proline-rich tyrosine kinase 2 (Pyk2) | TR-FRET counterscreen for FAK inhibitors |
Absorbance | null | 1,730 | null | 10 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | Counterscreen Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay | Counterscreen Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay |
Absorbance | null | 1,857 | null | 290 | null | null | null | FRET-based counterscreen assay for selective VIM-2 inhibitors: biochemical high throughput screening assay to identify epi-absorbance assay artifacts | FRET-based counterscreen assay to identify epi-absorbance assay artifacts |
Absorbance | null | 1,926 | null | 118 | null | null | null | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. | FRET-based counterscreen assay to identify epi-absorbance assay artifacts |
Absorbance | null | 435,026 | null | 507 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | Fluorescence Cell-Free Homogeneous Counterscreen to Identify Inhibitors of the RanGTP-Importin-beta complex | fluorescence resonance energy transfer (FRET)-based biochemical assay used as counterscreen |
Absorbance | null | 504,689 | null | 59 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen | uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay |
Absorbance | null | 720,541 | null | 416 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | qHTS for Inhibitors of the Phosphatase Activity of Eya2: Carboxyl-terminal binding protein (CtBP) Counterscreen for Cherry-picked Compounds | Carboxyl-terminal binding protein (CtBP) Counterscreen for Cherry-picked Compounds |
Absorbance | null | 1,159,604 | null | 51 | Identification of Compounds That Interfere with High-Throughput Screening Assay Technologies | (David, 2019, 10.1002/cmdc.201900395) | null | Counterscreen for inhibitors of ASK1: AlphaScreen-based biochemical high throughput dose response assay to identify inhibitors that optically interfere with alphascreen assays using TruHits beads | Counterscreen for inhibitors of ASK1: AlphaScreen-based biochemical high throughput dose response assay to identify inhibitors that optically interfere with alphascreen assays using TruHits beads |
Artifact | null | 485,270 | null | 701 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 1,040 | null | 501 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 628 | null | 1,396 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 1,672 | null | 942 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 449,739 | null | 940 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 2,239 | null | 175 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 2,661 | null | 191 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 488,975 | null | 383 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 504,558 | null | 48 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 2,098 | null | 923 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 624,304 | null | 1,150 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 485,273 | null | 1,119 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 873 | null | 853 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 2,221 | null | 243 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 720,511 | null | 548 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 686,996 | null | 393 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Artifact | null | 1,832 | null | 446 | Machine Learning Assisted Hit Prioritization for High Throughput Screening in Drug Discovery | (Boldini, 2024, 10.1021/acscentsci.3c01517) | null | null | One of Boldini2024 dataset which contains 13 different subdatasets. |
Autofluoresence | null | 587 | null | 34 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in Texas Red Spectral Region | null |
Autofluoresence | null | 588 | null | 25 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in Resorufin Spectral Region | null |
Autofluoresence | null | 589 | null | 6,214 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region | null |
Autofluoresence | null | 590 | null | 6,427 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in A350 Spectral Region | null |
Autofluoresence | null | 591 | null | 59 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in A488 Spectral Region | A488 Spectral Region; 480 nm and 540 nm excitation and emission |
Autofluoresence | null | 592 | null | 0 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in A647 Spectral Region | null |
Autofluoresence | null | 593 | null | 532 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in Fluorescein Spectral Region | 480 nm and 540 nm excitation and emission |
Autofluoresence | null | 594 | null | 32 | Fluorescence spectroscopic profiling of compound libraries | (Simeonov, 2008, 10.1021/jm701301m) | null | qHTS Assay for Spectroscopic Profiling in Rhodamine Spectral Region | null |
Autofluoresence | null | 709 | null | 3,590 | null | null | null | Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm | Autofluorescence at 339/460 nm; For fluorescent compounds, Dye equivalent concentration at given concentration > 10μm/ Fold Increase at 10μm; Blue non-fluorescent compounds need to be validated more than three times, while green non-fluorescent compounds should be validated more than five times. |
Autofluoresence | null | 923 | null | 779 | A small molecule inhibitor of Caspase 1 | (Boxer, 2010, https://www.ncbi.nlm.nih.gov/books/NBK56241/) | null | qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region | 405 nm excitation/520 nm emission |
Autofluoresence | null | 1,480 | null | 89 | Title: Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2 | (Strouse, 2010, https://pubmed.ncbi.nlm.nih.gov/23658968/) | null | Profiling compound fluorescence in IgMXP3 at 488/530 nm; counter screen to single point confirmation of ABCG2 screen | in IgMXP3 cells (ABCG2) 488/530 nm |
Autofluoresence | null | 1,483 | null | 83 | Title: Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2 | (Strouse, 2010, https://pubmed.ncbi.nlm.nih.gov/23658968/) | null | Profiling compound fluorescence in CCRF-Adr at 488/530 nm; counter screen to single point confirmation of ABCB1 screen | in CCRF-Adr (ABCB1 expressing cells) at 488/530 nm |
Autofluoresence | null | 1,696 | null | 342 | Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy- D-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC) | (Sivendran, 2010, 10.1016/j.bmc.2009.11.033) | null | Rml C and D fluorescent artifact dose-response confirmation | 340/460 nm |
Autofluoresence | null | 1,775 | null | 825 | null | null | null | Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission | on Avidin Beads with 488 nm excitation and 530 nm emission |
Autofluoresence | null | 1,776 | null | 489 | null | null | null | Profiling compound fluorescence on GSH Beads with 488 nm excitation and 530 nm emission | on GSH Beads with 488 nm excitation and 530 nm emission |
Autofluoresence | null | 2,124 | null | 198 | null | null | null | Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caused By Cell-Permeable Autofluorescent Compounds | 488nm excitation / 535 nm emission |
Autofluoresence | null | 2,757 | null | 9 | null | null | null | Test compound autofluorescence in Saccharomyes cerevisiae specifically s288c | 520 nm emission in Saccharomyes cerevisiae s288c |
Autofluoresence | null | 588,517 | null | 63 | null | null | null | Compound fluorescence counter screen for HTS for inhibitors of efflux pump with Cherry Pick1 compound set | 488 nm excitation |
Autofluoresence | null | 588,620 | null | 13 | null | null | null | Dose response compound fluorescence counter screen for HTS for inhibitors of efflux pump with Hit compounds from Cherry Pick1 | 488 nm excitation |
Autofluoresence | null | 624,483 | null | 10,930 | null | null | null | Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease | Spherotech Blue Array Particle kit |
Autofluoresence | null | 720,675 | null | 21 | null | null | null | qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells | 535 nm (green) in HepG2 cells |
Autofluoresence | null | 720,678 | null | 35 | null | null | null | qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells | 460 nm (blue) in HEK293 cells |
Autofluoresence | null | 720,680 | null | 13 | null | null | null | qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells | 535 nm (green) in HEK293 cells |
Autofluoresence | null | 720,681 | null | 37 | null | null | null | qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture | 460 nm (blue) in HEK293 cell |
Autofluoresence | null | 720,682 | null | 13 | null | null | null | qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture | 535 nm (green) in HEK293 cell |
Autofluoresence | null | 720,686 | null | 20 | null | null | null | qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture | 535 nm (green) in HepG2 cell |
Autofluoresence | null | 720,687 | null | 32 | null | null | null | qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells | 460 nm (blue) in HepG2 cells |
Autofluoresence | null | null | null | 216 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 80 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 39 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 209 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 80 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 37 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hepg2-p dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 210 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 56 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 33 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 224 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 44 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
Autofluoresence | null | null | null | 34 | High-Throughput Screening to Predict Chemical-Assay Interference | (Borrel, 2020, 10.1038/s41598-020-60747-3) | null | null | One of tox21-spec-hek293-p1 dataset which contains 6 different subdatasets. |
ColloidalAggregators | null | 585 | null | 1,256 | SCAM Detective: Accurate Predictor of Small, Colloidally Aggregating Molecules | (Alves, 2020, 10.1021/acs.jcim.0c00415) | null | Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) | null |
ColloidalAggregators | null | 1,476 | null | 4,500 | Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease | (Jadhav, 2010, 10.1021/jm901070c) | null | qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent) | Inhibitors of Cruzain (without detergent) |
ColloidalAggregators | null | 485,341 | null | 1,730 | SCAM Detective: Accurate Predictor of Small, Colloidally Aggregating Molecules | (Alves, 2020, 10.1021/acs.jcim.0c00415) | null | qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) | qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) |
ColloidalAggregators | null | null | null | 12,644 | An Aggregation Advisor for Ligand Discovery | (Irwin, 2015, 10.1021/acs.jmedchem.5b01105) | null | null | 20 diverse sources |
HeavyHitters | null | null | null | 13,068 | Modeling Small-Molecule Reactivity Identifies Promiscuous Bioactive Compounds | (Matlock, 2018, 10.1021/acs.jcim.8b00104) | null | null | PubChem2016, non-ChEMBL tested in at least 100 assays |
HeavyHitters | null | null | null | 1,000 | Statistical models for identifying frequent hitters in high throughput screening | (Goodwin, 2020, 10.1038/s41598-020-74139-0) | null | null | null |
HeavyHitters | null | null | null | 16,820 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 8,441 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 12,092 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 4,871 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 6,056 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 8,089 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
HeavyHitters | null | null | null | 1,544 | null | (Shi, 2024, 10.1093/nar/gkae424) | null | null | One of Shi2024 dataset which contains seven different subdatasets. |
LuciferaseInhibition | null | 411 | null | 1,571 | Characterization of chemical libraries for luciferase inhibitory activity | (Auld, 2008, 10.1021/jm701302v) | null | qHTS Assay for Inhibitors of Firefly Luciferase | ATP concentration in the assay (10 uM) |
LuciferaseInhibition | null | 1,006 | null | 2,976 | Characterization of chemical libraries for luciferase inhibitory activity | (Auld, 2008, 10.1021/jm701302v) | null | Counter Screen for Luciferase-based Primary Inhibition Assays | with >50% inhibition at 10 uM concentration |
LuciferaseInhibition | null | 1,379 | null | 565 | A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution | (Auld, 2009, 10.1021/jm8014525) | null | Counterscreen for Luciferase (Kinase-Glo TM) Inhibition | null |
LuciferaseInhibition | null | 1,891 | null | 446 | null | null | null | Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase | EC50 <= 1 log over the highest tested concentration |
LuciferaseInhibition | null | 2,515 | null | 10 | null | null | null | Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Probe SAR | NIH Chemical Genomics Center (NCGC) Assay |
LuciferaseInhibition | null | 2,530 | null | 46 | null | null | null | Secondary Assay for Luciferase (Kinase-Glo TM) Inhibition Counterscreen | null |
LuciferaseInhibition | null | 366,887 | null | 8 | null | null | null | Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assay | activity <= 10uM |
LuciferaseInhibition | null | 366,889 | null | 1 | null | null | null | Inhibition of Photinus pyralis luciferase assessed as maximum inhibitory potency by quantitative high throughput screening | activity <= 10uM |
LuciferaseInhibition | null | 366,891 | null | 19 | null | null | null | Inhibition of luciferin binding site of Photinus pyralis luciferase by competitive inhibition assay | activity <= 10uM |
LuciferaseInhibition | null | 488,838 | null | 41 | null | null | null | Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR | null |
LuciferaseInhibition | null | 493,175 | null | 0 | null | null | null | miR-21 counterscreen using purified firefly luciferase | null |
LuciferaseInhibition | null | 588,342 | null | 25,069 | Firefly luciferase in chemical biology: a compendium ofinhibitors, mechanistic evaluation of chemotypes, and suggested use as areporter. | (Thorne, 2012, 10.1016/j.chembiol.2012.07.015) | null | qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) | null |
LuciferaseInhibition | null | 588,498 | null | 18 | null | null | null | qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for the Campaign to Identify EBNA-1 Inhibitors project). | null |
LuciferaseInhibition | null | 602,357 | null | 104 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate | null |
LuciferaseInhibition | null | 602,358 | null | 102 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate and 500microM CoASH | null |
LuciferaseInhibition | null | 602,364 | null | 89 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM ATP | null |
LuciferaseInhibition | null | 602,474 | null | 53 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a biochemical assay with a commercial detection reagent - BriteliteTM Plus (PerkinElmer) | null |
LuciferaseInhibition | null | 602,475 | null | 36 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a biochemical assay with an in-house formulation of detection reagent | null |
LuciferaseInhibition | null | 602,476 | null | 31 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a cell-based translational read-through assay | null |
LuciferaseInhibition | null | 602,477 | null | 87 | null | null | null | FLuc inhibitory activity for the follow-up compounds in a cell-based assay to assess the activity of miR-21 | null |
LuciferaseInhibition | null | 624,030 | null | 104 | null | null | null | Biochemical firefly luciferase enzyme assay for NPC | null |
LuciferaseInhibition | null | 652,016 | null | 35 | null | null | null | qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set | null |
End of preview.