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A class I hydrophobin in Trichoderma virens influences plant-microbe interactions through enhancement of enzyme activity and MAMP recognition
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plant biology
|
Synthetic Promoter Designs Enabled by a Comprehensive Analysis of Plant Core Promoters
|
plant biology
|
A role for prefoldins in H2A.Z deposition in Arabidopsis
|
plant biology
|
Identification of hub molecules of FUS-ALS by Bayesian gene regulatory network analysis of iPSC model: iBRN
|
neuroscience
|
Differential encoding of safe and risky offers
|
neuroscience
|
Heart rate variability predicts decline in sensorimotor rhythm control
|
neuroscience
|
Commercial vaccines do not confer protection against two genetic strains of Piscirickettsia salmonis, LF-89-like and EM-90-like, in Atlantic salmon.
|
immunology
|
Leishmania donovani metacyclic promastigotes impair phagosome properties in inflammatory monocytes
|
immunology
|
Hunting Eagles with glass mice: revisiting the inoculum effect for Streptococcus pyogenes with a hollow fibre infection model
|
microbiology
|
Targeted capture and sequencing of Orientia tsutsugamushi genomes from chiggers and humans
|
microbiology
|
Design-of-Experiments In Vitro Transcription Yield Optimization of Self-Amplifying RNA
|
molecular biology
|
Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells
|
molecular biology
|
Sexually Transmitted Infections Select for Different Levels of Immunocompetence And Reproductive Efforts in The Two Sexes
|
evolutionary biology
|
Is Palmer's elm leaf goldenrod real? The Angiosperms353 kit provides within-species signal in Solidago ulmifolia s.l.
|
evolutionary biology
|
Monitoring the promoter activity of long noncoding RNAs and stem cell differentiation through knock-in of sgRNA flanked by tRNA in an intron
|
genetics
|
No evidence for general intelligence in a fish
|
animal behavior and cognition
|
DeepFrag: A Deep Convolutional Neural Network for Fragment-based Lead Optimization
|
pharmacology and toxicology
|
Competitive outcomes between native and invasive plants are linked to shifts in the bacterial rhizosphere microbiome
|
microbiology
|
Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila
|
molecular biology
|
Spatiotemporal Determination of Metabolite Activities in Multiple Corneal Epithelium Barriers on a Chip
|
bioengineering
|
UCsim2: 2D Structured Illumination Microscopy using UC2
|
cell biology
|
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
|
cancer biology
|
Strong and tunable anti-CRISPR/Cas9 activity of AcrIIA4 in plants
|
synthetic biology
|
Humanization of antibodies using a machine learning approach on large-scale repertoire data
|
immunology
|
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes
|
immunology
|
Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library
|
immunology
|
Targeting evolutionary conserved sequences circumvents the evolution of resistance in a viral gene drive against human cytomegalovirus
|
microbiology
|
Artemisia annua L. extracts prevent in vitro replication of SARS-CoV-2
|
microbiology
|
Clr4SUV39H1 and Bdf2BRD4 ubiquitination mediate transcriptional silencing via heterochromatic phase transitions
|
molecular biology
|
Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity
|
cell biology
|
Synaptojanin1 deficiency upregulates basal level autophagosome formation in astrocytes
|
cell biology
|
Microtubule-associated ROP interactors both delimit and transduce ROP signaling and regulate microtubule dynamics
|
cell biology
|
Moving patronin foci and growing microtubule plus ends direct the spatiotemporal dynamics of Rho signaling and myosin during apical constriction
|
cell biology
|
Joint development recovery on resumption of embryonic movement following paralysis
|
developmental biology
|
Low light intensity delays vegetative phase change in Arabidopsis thaliana
|
developmental biology
|
Mitochondrial fusion regulates proliferation and differentiation in the type II neuroblast lineage in Drosophila
|
developmental biology
|
Gut microbiota of Drosophila subobscura contributes to its heat tolerance but is sensitive to transient thermal stress
|
ecology
|
Novel functional sequences uncovered through a bovine multi-assembly graph
|
genomics
|
Measuring arterial pulsatility with Dynamic Inflow MAgnitude Contrast (DIMAC)
|
bioengineering
|
Auto-CORPus: Automated and Consistent Outputs from Research Publications
|
bioinformatics
|
Computing the Riemannian curvature of image patch and single-cell RNA sequencing data manifolds using extrinsic differential geometry
|
bioinformatics
|
Somatic mutations in CTCF zinc fingers produce cellular phenotypes explained by structure-function relationships
|
cancer biology
|
Genetic influences on brain activation and large-scale functional connectivity during nociceptive processing: a twin study
|
neuroscience
|
Loss of PIKfyve drives the spongiform degeneration in prion diseases
|
neuroscience
|
Test-retest reliability of tone- and 40 Hz train-evoked gamma oscillations in female rats and their sensitivity to low-dose NMDA channel blockade
|
neuroscience
|
Selective modulation of population dynamics during neuroprosthetic skill learning
|
neuroscience
|
Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection after sub-optimal vaccine dosing
|
immunology
|
Evolution in salmon life-history induced by direct and indirect effects of fishing
|
evolutionary biology
|
APOBEC1 mediated C-to-U RNA editing: target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in-vivo
|
bioinformatics
|
Cysteine is a limiting factor for glioma proliferation and survival
|
cancer biology
|
Genome-scale sequencing and analysis of human, wolf and bison DNA from 25,000 year-old sediment
|
developmental biology
|
Speech-like sounds dominate the human infant landscape
|
developmental biology
|
Dicer promotes genome stability via the bromodomain transcriptional co-activator Brd4.
|
genetics
|
Systematically quantifying morphological features reveals constraints on organoid phenotypes
|
systems biology
|
Aurora kinase A is essential for meiosis in mouse oocytes
|
cell biology
|
CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left-right symmetry breaking
|
developmental biology
|
Evolvability and constraint in the primate basicranium, shoulder, and hip and the importance of multi-trait evolution
|
evolutionary biology
|
Pathways and signatures of mutagenesis at targeted DNA nicks
|
genetics
|
Fatty acid oxidation participates of the survival to starvation, cell cycle progression and differentiation in the insect stages of Trypanosoma cruzi
|
biochemistry
|
DeepHBV: A deep learning model to predict hepatitis B virus (HBV) integration sites.
|
bioinformatics
|
Family cluster comparisons to detect infection by Mycobacterium leprae in at-risk populations of six endemic regions in Colombia.
|
microbiology
|
FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host
|
microbiology
|
LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA
|
microbiology
|
Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis
|
cell biology
|
Comparative dissection of the peripheral olfactory system of the Chagas disease vectors Rhodnius prolixus and Rhodnius brethesi
|
ecology
|
Choosing optimal trigger points for ex situ, in toto conservation of single population threatened species
|
ecology
|
RNA-directed DNA methylation prevents rapid and heritable reversal of transposon silencing under heat stress in Zea mays.
|
genetics
|
Distinguishing gene flow between malaria parasite populations
|
genomics
|
A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle
|
genomics
|
Transposable element landscape changes are buffered by RNA silencing in aging Drosophila
|
genomics
|
Role of extracellular mycobacteria in blood-retinal barrier invasion in a zebrafish model of ocular TB
|
immunology
|
Double drives and private alleles for localised population genetic control
|
synthetic biology
|
CRY2 missense mutations suppress P53 and enhance cell growth
|
cell biology
|
The collapse of genetic incompatibilities in a hybridizing population
|
evolutionary biology
|
Genetic modulation of initial sensitivity to Δ9-tetrahydrocannabinol (THC) among the BXD family of mice
|
genetics
|
Distinct spermiogenic phenotypes underlie sperm elimination in the Segregation Distorter meiotic drive system
|
genetics
|
Chromosome-scale assembly of the Sparassis latifolia genome obtained using long-read and Hi-C sequencing
|
genomics
|
Heparin-modified alginate microspheres enhance neovessel formation in hiPSC-derived endothelial cells and heterocellular in vitro models by controlled release of VEGF
|
bioengineering
|
AncestralClust: Clustering of Divergent Nucleotide Sequences by Ancestral Sequence Reconstruction using Phylogenetic Trees
|
bioinformatics
|
rdrugtrajectory: An R Package for the Analysis of Drug Prescriptions in Electronic Health Care Records
|
bioinformatics
|
Semi-supervised Calibration of Risk with Noisy Event Times (SCORNET) Using Electronic Health Record Data
|
bioinformatics
|
COMPARE, an ultra-fast and robust suite for multiparametric screening, identifies phenotypic drug responses in acute myeloid leukemia
|
cancer biology
|
Anti-stress effects of the glucagon-like peptide-1 receptor agonist liraglutide in zebrafish
|
pharmacology and toxicology
|
Cofactor specificity of glucose-6-phosphate dehydrogenase isozymes in Pseudomonas putida reveals a general principle underlying glycolytic strategies in bacteria
|
systems biology
|
Host-pathogen Immune Feedbacks Can Explain Widely Divergent Outcomes from Similar Infections
|
systems biology
|
Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC-induced neurons with the V337M MAPT mutation
|
neuroscience
|
Effects of Ih and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons
|
neuroscience
|
Human gut bacteria produce TH17-modulating bile acid metabolites
|
immunology
|
Local Shifts in Inflammatory and Resolving Lipid Mediators in Response to Tendon Overuse
|
immunology
|
The effect of root exudates on the transcriptome of rhizosphere Pseudomonas spp.
|
microbiology
|
Targeting the artemisinin resistant malaria by repositioning of the anti-Hepatitis C Virus drug Alisporivir
|
microbiology
|
Biotechnological exploitation of Saccharomyces jurei and its hybrids in craft beer fermentation uncovers new aroma combinations.
|
microbiology
|
Controlled spatial organization of bacterial clusters reveals cell filamentation is vital for Xylella fastidiosa biofilm formation
|
microbiology
|
Gut microbiome features are associated with sepsis onset and outcomes
|
microbiology
|
Shear-Mediated Platelet Activation is Accompanied by Unique Alterations of Platelet Lipid Profile
|
cell biology
|
Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis
|
cell biology
|
An "individualist" model of an active genome in a developing embryo
|
developmental biology
|
Does land use matter? Carbon consequences of alternative land use futures in New England
|
ecology
|
Explosive diversification following continental colonizations by canids
|
evolutionary biology
|
Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy
|
biochemistry
|
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