diff --git "a/Data/transcripts/4F_RBc1akC8_20241225194724.txt" "b/Data/transcripts/4F_RBc1akC8_20241225194724.txt" new file mode 100644--- /dev/null +++ "b/Data/transcripts/4F_RBc1akC8_20241225194724.txt" @@ -0,0 +1,3338 @@ +[Music] +welcome to the hubman lab guest Series +where I and an expert guest discuss +science and science-based tools for +everyday +life I'm Andrew huberman and I'm a +professor of neurobiology and +Opthalmology at Stanford school of +medicine today March the 3D episode in +our sixth episode series all about sleep +with expert guest Dr Matthew Walker +during today's episode we discuss how to +structure your sleep for optimal mental +health physical health and performance +we discuss monophasic sleep schedules +which are the more typical sleep +schedule where you go to sleep at night +and then wake up in the morning so +sleeping in one bout as opposed to +polyphasic sleep schedules which are +when you sleep in two or more bouts +either at night or perhaps a shorter +bout of sleep at night and another bout +of sleep during the day we also discuss +naps including how to nap how long your +nap should be whether or not naps are +good or bad in particular whether or not +they're good or bad for you it turns out +this varies according to individual we +also discuss how your needs for sleep +and naps vary across the lifespan and we +discuss body position during sleep which +might seem excessively detailed but it +turns out that body position during +sleep is critical for ensuring that the +sleep you get is optimally restorative +as with the first two episodes of this +six episode series today's third episode +is filled with both science that is the +biology of sleep and napping and body +position and how those relate to one +another as well as practical tools that +you can use to vastly improve your sleep +before we begin I'd like to emphasize +that this podcast is separate from my +teaching and research roles at Stanford +it is however part of my desire and +effort to bring zero cost to Consumer +information about science and science +related tools to the general public in +keeping with that theme I'd like to +thank the sponsors of today's podcast +our first sponsor is betterhelp +betterhelp offers Professional Therapy +with a licensed therapist carried out +online now I've been doing therapy for +well over 30 years initially I had to do +therapy against my will but of course I +continued to do it voluntarily over time +because I really believe that doing +regular therapy with a quality therapist +is one of the best things that we can do +for our mental health indeed for many +people it's as beneficial as getting +regular physical exercise the great +thing about better help is that it makes +it very easy to find a therapist that's +optimal for your needs and I think it's +fair to say that we can define a great +therapist as somebody with whom you have +excellent Rapport somebody with whom you +can talk about a variety of different +issues and who can provide you not just +support but also insight and with better +help they make it extremely conven vent +so that it's matched to your schedule +and other aspects of your life if you'd +like to try betterhelp you can go to +betterhelp.com huberman to get 10% off +your first month again that's +betterhelp.com +huberman today's episode is also brought +To Us by element element is an +electrolyte drink that has everything +you need and nothing you don't that +means plenty of the electrolytes +magnesium potassium and sodium and no +sugar as I mentioned before on this +podcast I'm a big fan of salt now I want +to be clear people who already consume a +lot of salt or who have high blood +pressure or who happen to consume a lot +of processed foods that typically +contain salt need to control their salt +intake however if you're somebody who +eats pretty clean and you're somebody +who exercises and you're drinking a lot +of water there's a decent chance that +you could benefit from ingesting more +electrolytes with your liquids the +reason for that is that all the cells in +our body including the nerve cells the +neurons require the electrolytes in +order to function properly so we don't +just want to be hydrated we want to be +hydrated with proper electrolyte levels +with element that's very easy to do what +I do is when I wake up in the morning I +consume about 16 to 32 ounces of water +and I'll dissolve a packet of element in +that water I'll also do the same when I +exercise especially if it's on a hot day +and I'm sweating a lot and sometimes +I'll even have a third element packet +dissolved in water if I'm exercising +really hard or sweating a lot or if I +just noticed that I'm not consuming +enough salt with my food if you'd like +to try element you can go to drink +element spelled LM nt.com huberman to +claim a free element sample pack with +your purchase again that's drink element +LM +t.com today's episode is also brought To +Us by waking up waking up is a +meditation app that has hundreds of +different meditations as well as scripts +for Yoga Nidra and non-sleep deep rest +or nsdr protocols by now there is an +abundance of data showing that even +short daily meditations can greatly +improve our mood reduce anxiety improve +our ability to focus and can improve our +memory and while there are many +different forms of meditation most +people find it difficult to find and +stick to a meditation practice in a way +that is most beneficial for them the +waking up app makes it extremely easy to +learn how to meditate and to carry out +your daily meditation practice in a way +that's going to be most effective and +efficient for you it includes a variety +of different types of meditations of +different duration as well as things +like Yoga Nidra which place the brain +and body into a sort of pseudo sleep +that allows you to emerge feeling +incredibly mentally refreshed in fact +the science around Yoga Nidra is really +impressive showing that after a yoga +needra session levels of dopamine in +certain areas of the brain are enhanced +by up to 60% which places the brain and +body into a state of enhanced Readiness +for mental work and for physical work +another thing I really like about the +waking up app is that it provides a +30-day introduction course so for those +of you that have not meditated before or +getting back to a meditation practice +that's fantastic or if you're somebody +who's already a skilled and regular +meditator waking up has more advanced +meditations and yoga needer sessions for +you as well if you'd like to try The +Waking Up app you can go to waking +up.com huberman and access a free 30-day +trial again that's waking up.com +huberman and now for my conversation +with Dr Matthew Walker Dr Walker welcome +back Dr huberman an absolute pleasure +let's talk about the different types of +sleep because I think most people think +of sleep as just one thing most people +sleep at night some people also nap a +topic we'll also discuss today +but turns out there are a lot of +different different types of sleep what +are the different types of sleep and +what do they do for us and um I guess +everyone's probably wondering already I +certainly am what types of sleep are we +already engaging in meaning am I +involved in or having multiple types of +sleep each night this is a fascinating +question and it comes back to something +we've discussed in a previous episode +the different stages of sleep and how +they unfold we've described that +fascinating stuff what you're already +asking though is is an incredibly sort +of subtle but relevant question how +should I be sleeping in terms of the +phases of sleep should I have one phase +should I have two phases of sleep or +should I have many phases of sleep in +some ways you can answer that question +on the basis of the lifespan because how +it is that we sleep in terms of those +chunking sessions changes as we +develop to be clear in +nomenclature I'm saying monophasic basic +polyphasic unpack that monophasic +obviously just simply means a single +phase monophasic when you say phase you +mean one bout of sleep correct so that +would be within a 24-hour period you are +having a single bout of sleep basic then +means that within that 24-hour phase you +are having two bouts of sleep and we'll +speak about how those bouts are split up +are they split up between two halves in +the middle of the night or are they +split up in terms of longer at night +Siesta like nap in the afternoon and +then we can speak about polyphasic sleep +polyphasic sleep we in sleep science +have been using for many years in the +context of infancy because there as any +new parents will know infants do not +just simply have a nice single bout of +sleep they're up they're down they're up +they're down and have many bouts of +sleep within that 24-hour period and +that's polyphasic sleep the other term +or the other application of that term +polyphasic sleep has been used more so +in the sort of interesting biohacker +movement and we can we'll come back to +that perhaps later on so how do these +different phases of sleep change across +the lifespan well we've already said +that when you're an infant and you're +first born within the first year of life +you are incredibly poly phasic and you +are probably going through wake sleep +phases every 2 hours why do you do that +why can't you just simply be born and +sleep in a monophasic way it's for at +least two reasons first an infant needs +to feed every two hours so their energy +needs and their food intake requirements +dictate that you can't sleep for very +long because you need to be awake to +feed and then you go back to +sleep Within probably the first six +months things will start to to change a +little bit but the second reason that +you are highly polyphasic when you are +first born is because your super +chiasmatic nucleus and in another +episode we spoke about this Central +master 24-hour clock that beats out your +Cadian Rhythm the rise and the fall the +wake and the sleep that has not yet +developed it hasn't been glued into +place into the brain this 24-hour clock +so the infant seemingly knows nothing +about when it's light or when it's dark +outside that just awake or sleep awake a +sleeve so that's the second reason +energy feeding needs is the first and +then an absence of yet a fully developed +24-hour clock in the brain to beat out +that beautiful dictated Rhythm by about +age one that number of phases of sleep +are starting to decrease but it's still +highly polyphasic it's not not until you +get to probably age two or three that +now you're starting to see this +consolidation of sleep what do I mean by +that sleep is now happening more +dominantly in the night phase of the +24-hour cycle and there a few abouts of +sleep during the +daytime then perhaps by the time you're +in kindergarten you may be down to just +two sleeps so now we've switched from +polyphasic sleep as infants to basic +sleep as kindergarten could you describe +that it was basic patterns I recall in +kindergarten um having nap time in the +afternoon yeah they put out these little +mats and every every kid would just kind +like roll up it's actually sounds really +nice it's one you know wouldn't and +we'll speak about how some adults do +this too but almost every kindergarten +system that I've inquired about around +the world different nations they all +have this nap time and Any teacher will +tell you if one of those children does +not nap during that period of time they +are the Loose Canon they are the live +wire and in subsequent episodes we'll +speak about exactly how sleep harnesses +and improves our emotional and mental +health and how it falls apart when we +don't so that that's how it certainly is +emerging biologically and that's how we +as a society respect that and +accommodate that +and then probably by the age of starting +school so sort of five or six now we're +starting to see fully monophasic sleep +children sleeping long bouts at night +and then being able to sustain +wakefulness during the day at that point +you have locked in your monophasic +pattern and that will continue +throughout adulthood and into old age +with a few caveats that we'll speak +about so that's how sleep sleep unfolds +in the monophasic biphasic polyphasic +sleep across the lifespan it doesn't +quite tell you however how those +different stages of sleep change across +the lifespan so I've shown you the view +of sleep across the lifespan through one +lens of the microscope if we click down +one lens and focus more deeply on the +different stages of sleep there we see a +fascinating +story in uo for the most part you are in +a sleep likee State as a fetus once you +get to a certain point of +development in utero that sleep-like +state seems to be more so something that +looks like REM sleep now it's not fully +fledged full fat REM sleep yet but it +seems to be something very much like REM +sleep I say this because in the first +episode I told you as we go into REM +sleep +and we start to as adults dream the +brain paralyzes the body so that the +mind can dream safely those kicks and +those punches and those elbows that uh a +mother will feel from the fetus seem to +be during this dream state often and I +don't want to shatter any illusions of +you start singing or you're cing and you +get these bumps and these elbows and +these legs kicking and it's beautiful it +is beautiful but it turns out that it's +probably the REM sleep state but the +muscle sort of paralysis has not yet +developed so you're getting these +electrical burst this frenetic activity +of REM sleep that we described but +you're not getting any of the blockade +of the motor output and so it expresses +itself as these kicks and these +bumps and then during the first six +months of life and at that point in the +first 6 months those infants are +sleeping anywhere between 14 to 17 hours +a day that's it's immense isn't it I +mean it's right up there if you look +across the across philogyny and you ask +which is by the way a fascinating Topic +at some point we should do a a separate +podcast on sleep across different +species because I know like me you love +you know the whole variety of sweet but +you've got elephants who will sleep as +little as 4 hours and then you've got +the little brown bat who is the rock +star of sleep and it will sleep sleep +almost 17 to 18 hours a day it nudges +out the sloth in that sense wow can I +ask you a question about that little +brown P yeah does it sleep hanging +upside down does so it can't have sleep +paralysis in its little claws so it it +will it will not have that paralysis but +it goes through the stages of sleep very +quickly and this happens with birds as +well so birds that flock on a branch +they will sleep and they sleep in some +fascinating ways what some sometimes +with one half of the brain sometimes +with both halves but then you say well +if I'm on a branch and there's this +wonderful Force called gravity +underneath me and I go into REM sleep +and I have that muscle paralysis which +they do how does that work well they +only have very brief REM sleep periods +that last just for a few seconds and +then they regain their muscle tone got +it couldn't couldn't help but ask it's +genius the Flora and the fauna I +especially that the fauna um enchant me +that much so I don't want to draw us off +course but now we know that they they +can that's why the bats don't fall +that's why the birds Don't Fall correct +um so when you are then as an infant +sleeping 14 to 17 hours what's happening +with those different stages of sleep +non-rem and REM at that point we can't +really Define and separate the different +stages of non-r because it's not yet +fully formed but we have what looks like +a REM sleep active State and a a deep +non-rem sleep passive state almost 50% +of the time that an infant a newborn is +asleep is spent in REM sleep why do I +say that with some kind of wonder in my +voice because as adults we're perhaps +down to maybe 20% of our time spent +asleep is in REM sleep but 50% of the +time when an infant is asleep they are +in rem why would this be the case and +across all species that have REM and +non-rem the time when we see REM sleep +in highest volume amount is always after +birth there is something special about +REM sleep and its function during that +early period and we now start to +understand why when you are first born +you are still going through a huge +amount of brain +maturation and the recipe for the day +there unlike when we are teenagers is +exploding the brain with synapses all of +these connections throughout the brain +what we've discovered is that REM sleep +acts as an electrical fertilizer to +stimulate the growth of these +connections within the brain it's almost +as though you could think about an +internet service provider with this huge +new neighborhood and the first call of +business is to go in and wire up each +one of those homes with these Fiber +Optic Cables that's what REM sleep is +doing and if you start to deprive and +these were studies gosh done many years +ago by Howard rthor and others if you +deprive animals of REM sleep you stunt +the developmental growth of the brain +and presumably the whole animal and the +yeah as a consequence I mean if you look +at its social behavior even just that +it's profoundly abnormal because you +don't have that REM sleep developed +brain I mention this not because there +is any causal evidence but we have seen +REM sleep deep impairments in certain +developmental +disorders such as autism as well as ADHD +I don't think there is any supportive +evidence yet to come out with a claim +that part of the trajectory underlying +those conditions is abnormalities of REM +sleep but I it's a very active area of +research so it's a fascinating time +though during infancy when you get these +huge amounts of REM sleep why because of +what we call synaptogenesis is which is +simply the creation of sinapsis +Genesis then as you move from 6 months +across the next 18 months something odd +happens Total Sleep time starts to +decrease REM sleep starts to decrease +but non-rem sleep actually increases +even though Total Sleep time is +decreasing and there's a strange peak in +lighter stage nonrem what we call stage +two nonr and those sleep spindles that I +was describing in the first episode +These bursts of electrical +activity we will speak about the role of +those sleep spindles in improving motor +skill learning and we've done a many +many years of work in this area why is +that relevant to this phase of life +that's right around the time when +infants start to coordinate their limbs +in a skilled way and begin to walk and +we believe that it is part of the +process of the development of the motor +system enabling walking to begin amazing +so then things will change further sleep +time continues to decrease and by about +age five or six now the cocktail blend +of nonrem and REM is down to a stable +ratio that will remain throughout the +lifespan which is a 4:1 ratio so about +20% of the time that you're asleep will +be REM sleep and the remaining time time +will be 80% of that time will be non-rem +sleeping provided one is getting +sufficient total amounts of sleep +correct and getting it at the right +moments in time that we described in the +first episode getting that sort of that +appropriate chronotype match to the +24-hour clock that will certainly alter +those things too so that's how sleep +unfolds both at the first level of the +lens monophasic basic polyphasic and +then double clicking how the different +stages of sleep unfold and what the +reasons are behind that I then said once +we're adults we become +monophasic yes to a degree but there is +some contention about the way that we +sleep in modernity that we may not be +sleeping in the way that we were +designed to sleep which brings us back +to basic sleep in the first episode we +spoke about this strange after afternoon +dip in our alertness that happens called +the postprandial dip and it happens +somewhere between the 1 to 4:00 p.m. +region and it's measurable and it seems +to be biologically wired into +us if you look at certain cultures that +are not touched by modernity so we and +others have studied studied hunter +gatherer tribes they don't quite sleep +the way that we do and they don't sleep +the way that we do for at least two +reasons the first is that they will +often have a siesta like pattern of +behavior where especially in the hot dry +season they will take a nap in the +afternoon in the wet cooler season that +may not be the case but they certainly +have more of a basic pattern where +they'll sleep longer at night and then +have a short nap Siesta like and then of +course there are Latin and Mediterranean +cultures and they have this practice of +the Siesta like Behavior coming back to +the hunter gather tribes the way that +they also do not sleep in a similar +manner to that which we do is the timing +of sleep they don't go to sleep as the +sun goes down they will usually on +average as a group they will usually go +to sleep about 2 hours after Sundown and +then they will wake up not with the +rising of the sun they wake up just +before that and you think how are they +predictive of the light no the thing +that changes first before the sun truly +Rises is +temperature and temperature is a very +strong predictor that forces them +awake so when you think about how +they're sleeping then consider the term +midnight most of us never really think +about what the term means midnight +refers to the fact that it is the middle +of the night but for most of us in the +modern world that's the time when we're +thinking about sending our last email or +posting to social media midnight is no +longer midnight for society but it is +for them so should we be thinking about +midnight as the middle of the night in +the context of the uh extreme early +person morning person who you know +presumably likes to go to bed around +8:00 P.M wake up around 4:00 a.m. most +people hear 4:00 a.m. and they go oh +goodness you know that's early sort of +um you know like the the mighty Joo +willink is is uh famous for posting +images of his of his uh digital watch +usually I think it's 4:30 a.m. wake up +and that's when he starts his workout so +his Twitter and I guess they call X now +feed and and Instagram is a replete with +images of his watch 4:30 and people +think goodness that's early right but he +was a guest on this podcast spoken to +him before but he goes to bed pretty +early that's right most nights so in +some sense you know midnight for him or +for somebody with a similar schedule is +truly middle of the night that's right +right but for the other chronotypes for +people that uh prefer to go to sleep or +who naturally um get sleepy around 10 or +11 p.m. or even later um how should they +think about this biphasic polyphasic +business because um at at some level um +we all have to +reconcile uh our sleep schedule with the +with the demands of work and family and +so on that's right so I was very +specific when I said the hunter gather +of tribes on average that's the way that +they will sleep but like the rest of +society there's a huge distribution and +there will be some proportion of them +who are a little bit like Joo who will +be on the early side of that on the very +early side of that but then there are +other people who are clear night owls +and they may not be going to bed until +you know 10: or 11: and waking up +later so there is a distribution there +you don't have to worry that my +statement of midnight on average that +does seem to be when we are dislocated +from all of the trappings of modernity +how a group of Representative humans on +average will sleep but there is huge as +I said differences from one individual +to the next by the way you can ask the +question why do we have these things +called chronotypes why is there such +variability in how people have a +preference for when they sleep wouldn't +it just be easier if +biology designed us all to be asleep at +the same time not so we mentioned in the +first episode that sleep is truly +idiotic in the sense that you know +you're not protecting yourself or the +people that you care about and if +everyone slept at the same moment in +time you as a collective and as an +individual would be vulnerable for an 8 +hour period 7 to n hour period but by +way of this wonderful injection of +variability as to preferences for when +people sleep maybe there are some people +who are going to bed at 8:00 p.m. and +there are other people and they're +waking up at 4: a.m. there are other +people who go to bed at midnight and +wake up at 8:00 a.m. so then think about +that at some point what you've done is +that there will always be someone or +collection of people awake until +midnight and then will always be a +collection of people who are awake +starting at 4:00 a.m. +so as an individual everyone gets their +8-hour opportunity but as a collective +as a clan you are you've reduced your +vulnerability down by 50% because Mother +Nature injected the variability by way +of genetics of chronotype to distribute +that and lessen the burden does that +make any sense it does and it reminds me +of how the Circadian rhythm which we +discussed in episode one is about 24 +hours not exactly 24 hours the rhythm of +the supermatic nucleus neurons that +generate the Circadian rhythm as I +recall uh is rarely exactly 24 hours +it's 24.2 or 24.4 and the idea in mind +the just so story uh is that that +variation allows for entrainment +matching to the outside light dark cycle +which changes across the year so you +don't want it rigidly 24 hours because +if there's any variation in light dark +which of course there is you know even +at the equator across the year there's +subtle variations but certainly As you +move away from the equator and so these +these uh variations in you know your +circadian rhythm uh clock scn supermatic +nucleus might be 24.2 mine might be 24.6 +24 someone else +24.1 and in that sense um allows some uh +malleability to to matching the +Circadian rhythm to outside light dark +rhythms is that is that a a decent +parallel for what we're talking about +it's a beautiful demonstration that +there is always some it's almost wiggle +room in how biology is programmed +because some degree of sort of noise +almost sarcastic noise can be very +beneficial and it's much more predictive +of the way in which the world works and +it's much more adaptive for a species to +enact and to embrace that kind of +variability and yours was a beautiful +example +that it's about 24 hours but it's +certainly responsive to changes in light +duration across the year and it has to +be because we need to buckle ourselves +to the light dark cycle for optimal +survival and here is another +demonstration of where it's not about +the Cadian Rhythm but it's about the +chronotype distribution not within an +individual across the year but across +individuals at any one moment in time +and that variability once again provides +a biological +benefit in the first episode and again +now you're discussing chronotypes and +one one thing that I've been meaning to +ask is you said that chronotype is +genetically determined but that +necessarily mean it is directly +inherited from Mom Andor dad meaning if +your parents are both extreme early +morning types will you grow up to be an +extreme early morning type you already +established that during infancy and +development uh adolescence Etc that our +chronotype is somewhat masked by some of +the developmental uh um uh Necessities +um but once we reach young adulthood and +and our chronotype has been established +uh can we look to our parents to +determine whether or not we are more +likely to be in morning person or or +late shifted it's very unlikely to find +find anyone whose parents were both +extreme morning types who is a neutral +or an evening type and vice versa so my +guess is that people with if they know +of their biological parents and they +know of their rhythms it's highly likely +that you will at some point acquas in +your lifetime to being very similar to +them now there are certain life +conditions and contexts where you can +you know fight that um if you're really +into you know if you're someone who is +in punk rock band and you're touring all +the time even though your mom and dad +may be morning types and you may be a +morning type you're on the road you're +playing gigs there's no chance but at +some point let's say you retire and you +give yourself the opportunity to express +your natural Rhythm you will go back to +that so yes it's highly genetic it's not +enre highly genetic there is some degree +of modification that happens on the +basis of context and I've just given you +a good example of context and also your +exposure to light you can be someone who +is let's say a neutral like me but if +you're constantly invaded by Electric +Light at night you're drinking too much +caffeine and you're on your laptop and +your computer and your phone and you're +always activated by social media it's +very easy for someone like me to drift +and become a 1 a.m. to you know 9 a.m. +person that's not my natural type but +context and the environment have shifted +me but for the most part yes to your +question I'd like to take a brief break +and acknowledge our sponsor ag1 ag1 is a +vitamin mineral probiotic drink that +also contains adaptogens and is designed +to meet all of your foundational +nutritional needs by now I'm sure you've +all heard me say that I've been taking +ag1 since 201 12 and indeed that is true +now of course I do consume regular Whole +Foods every day I strive to get those +Foods mostly from unprocessed or +minimally processed sources however I do +find it hard to get enough servings of +fruits and vegetables each day so with +ag1 I ensure that I get enough of the +vitamins minerals Prebiotic fiber and +other things typically found in fruits +or vegetables and of course I still make +sure to eat fruits and vegetables and in +that way provide a sort of insurance +that I'm getting enough of what I need +in addition the adaptogens and other +micro nutrients in ag1 really help +buffer against stress and ensure that +the cells and organs and tissues of my +body are getting the things they need +people often ask me that if they were +going to take Just One supplement what +that supplement should be and I always +answer ag1 if you'd like to try ag1 you +can go to drink a1.com huberman to claim +a special offer you'll get five free +travel packs plus a year supply of +vitamin D3 K2 again that's drink a1.com +huberman okay so getting back to these +different uh phase opportunities for +Sleep uh clearly I'm getting the +language wrong here but vacular +monophasic basic and polyphasic um could +you give us a few more examples of +different types of biphasic and +polyphasic sleep so coming back to basic +sleep I describe one version once we are +adults which is the Siesta like notion +one long bout at night short bout during +the day and that bout during the day is +usually matching that drop in alertness +that we described it sort of hits that +sweet spot right there and it's quite +easy for some people to fall asleep in a +period between somewhere between one and +four 1 to four yeah and I know it's a +large window but that just allows us to +sort of know okay if you're someone like +yourself who's a morning type you would +probably start to want to nap a little +bit earli or if you were basic someone +like me a neutral probably an hour and a +half two hours later still +but there is a different version of +basic sleep for adults that has been +described in the literature and it's +fascinating but I don't think it's +biological it's the notion that some +people will have heard called first +sleep second sleep and now you are +splitting your sleep into two phases but +they're split across the night so the +idea is that you fall asleep and you'll +maybe have 4ish hours and then you wake +up and you then are awake for several +hours and then you go back to sleep for +another 3 or 4 +hours if you look in history and the the +record of of human history it's very +clear that there were some cultures +doing this particularly if you look at +some of the European cultures Great +Britain in particular there is good +evidence that somewhere between about +the 15th to 19th century seems to have +ended during the kind of dezian +era people were describing this behavior +and they would wake up in the middle of +the night after about 4 hours they would +make food they would play music they +would write they would make love it was +a real thing and I'm not suggesting that +it did not happen it clearly did and +there's a there a great book that +outlines this but is it the way that we +were designed to sleep bif phasically +versus the Siesta like and I don't think +it is there is no good collection of +evidence if you look at the biology of +our human rhythms that argues that there +is this magical period of a huge spike +in Arcadian Rhythm that happens right in +the middle of the night that should +force us +awake there is one paper that's often +cited for this and in truth that paper +if you read it says nothing about first +sleep second sleep doesn't speak about +basic sleep at all +and that paper I think is unfairly used +as a justification of first sleep and +second sleep and the paper to me has at +least three problem it's a great paper +there's no no problem with the paper and +its hypothesis but its use as +justification for first sleep second +sleep has three +problems the first is the artificial +nature of the study they weren't +designing it to test the hypothesis but +they had individuals in bed for 14 hours +relative to a standard 8 hour period and +sure enough what they found was that +when you force people night after night +to be in bed for 14 hours somewhere +after about 6 or 7 hours they wake up +and then you can't get out of bed in the +study so you just lie awake and then at +some point I don't know if it's through +boredom or you drift back off into sleep +and that was argued as a clear +demonstration of this split sleep but as +I said they're awake usually for about +six and a half seven +hours also there was no magical +Awakening period it's a probability +distribution and what that means is if +you look at the data it's just more +likely that people will wake up after +about 6 or seven hours and they're more +likely that they will go back down into +sleep it wasn't as though the whole +experiment demonstrated a very clear +termination of sleep that everyone had +at that moment in time so that's the +first +issue um and the second issue which is +first issue it's kind of an abnormal +thing 14 hours forced in bed the second +is it wasn't a clear separation it's +just simply higher probability the final +issue is that it was a study done in +only seven individuals healthy males and +so I have yet to see it you know scaled +up did it happen first sleep second +sleep yes it did is there any strong +evidence that that's how we naturally +were designed and have evolved to sleep +I in truth I don't think so at least I +don't see good evidence right now +supporting that but remain open to it in +episode one we talked a little bit about +body position during sleep uh and how +different uh degrees of uh incline or +decline might impact uh some of the +features of sleep and I can't help but +ask now as you uh described this basic +pattern for people that were essentially +experimentally restricted to to the bed +um is there something about being +horizontal that makes us +sleepy there is and it's perhaps not for +the reasons that you would think which +is okay I'm just pre-programmed when I +lie down and my head hits the pillow it +turns out that it seems to be +temperature that when your body is +recumbent lying flat +horizontal the distribution of how your +body is able to move blood around the +different regions and decrease your core +body temperature meaning it can push +blood warm blood out of the core of your +body to these surface areas and when you +push it out to the surface areas you +release that heat it's this huge thermal +dissipation that happens when we move +Blood Out Of The Core to the surface you +emit that heat and your core body +temperature plummets when your body +temperature your core body temperature +decreases you have a higher likelihood +of sleepiness in fact it's very +difficult for you to fall asleep if your +core body temperature does not drop and +by lying down the body's what we call +vasoactive ability to distribute that +blood in a way that is permissive for +thermal dissipation of core body +temperature is superior and that's the +reason why we find it easier to fall +asleep lying down than let's say +semi-recumbent or certainly propped all +the way up and it's probably the reason +naturally we evolve just to lie down on +the floor very +interesting maybe now is a good time to +talk +about basic sleep in the context of a +about of sleep at night and the +afternoon nap you've mentioned this +postp parial dip that most people +experience between 1: and 400 p.m. that +many people try and combat with caffeine +we will also talk about Caffe +uh this episode um such an interesting +substance and I think the most commonly +used drug it is a drug after all +worldwide I think more than +90% of adults worldwide consume caffeine +on a daily basis that's correct and I +believe it is after oil it may +be perhaps the second or at least the +third most traded commodity on this +planet and it is what we call a +psychoactive stimulant is a stimulant +and it's probably one of the only +stimulants that we will readily give to +our children and you know not be too +concerned about it we'll get to caffeine +in depth uh a little bit later in this +episode but I can't help but uh just +mention that someone I think it was +Michael Polland said that you know +caffeine is one of the few drugs that +almost everybody takes just to quote +unquote feel normal yeah exactly you +know it's sort of I think sometimes you +know sleep deprivation is is +simply just the absence of of caffeine +and um so it's a very interesting +chemical which I have in truth changed +my mind on and I'm happy to speak about +why I've changed my mind but also some +God rails too well we'll we'll go there +meanwhile I'll take a sip of my uh +Triple Espresso here as we discuss as we +discuss naps are naps good for us should +we nap what if we don't like naps why do +we wake up from naps groggy sometimes +and other times we feel refreshed tell +us about +napping naps are both good and bad +depending on the situation naps can be a +double-edged sword in other words we and +others have done lots of studies on naps +and the benefits are fascinating and St +I'll tell you about one study we did we +had participants assigned to one of two +groups and at midday they all learned a +whole list of new facts so it was a +study about learning in memory and then +one group took a 90-minute sleep +opportunity sort of focused right around +that drop in alertness the other just +remained awake lying on a bed and they +just watched a nature +documentary and then 5 hours later we +had them do another learning session and +so they've woken up after the 90-minute +nap they've got through that sort of +initial lull that we'll discuss what +that is after you wake up everyone's now +back to operating temperature so in +other words I've had you try to cram in +a whole list of facts at midday and then +a whole list of facts new facts again at +5 p.m. and I can ask what is the +learning capacity of your brain at +midday and at 5:00 p.m. and is there any +difference in your learning ability when +you have had a nap in between versus not +and sure enough what happened in the +group that did not nap their learning +capacity gradually declined across the +day the nap group they were able to +sustain their learning and in fact if +anything improve it and the difference +between those two groups at 5:00 p.m. +was about +20% so that's certainly non-trivial in +terms of if you to say you know here's a +new compound that can boost your +learning capacity by 20% would you take +it I suspect it would probably make some +money so that's a demonstration of for +learning in memory we did another study +very much like that in terms of its +design but we looked at your emotional +brain and we were showing people +different types of emotional expressions +and having them rate them and we did +that firstly before an appp and then +after a na versus um that same time in +sort of midday versus 5:00 p.m. and +another group did not nap and sure +enough the group that did not nap +by about 5:00 p.m. they were starting to +rate fearful faces and angry faces as +much more fearful and much more angry +but if you looked at the group that +napped it was different they actually +lessened the response to fear and they +blunted the normal increase in Anger +sensitivity across the day and the nap +seemed to boost how positively you rated +happy faces +so a nap there had the ability to reset +the magnetic north of your emotional +compass and there was a beneficial +almost added Rose tint to your world viw +glasses after You' napped what was also +interesting in those two studies two +different types of sleep were +transacting those benefits in the nap +group that was doing the learning the +learning benefit that they got wasn't +just about them napping and sleeping it +was about them having these sleep +spindles the more of those sleep +spindles that you had the greater the +restoration of your learning capacity +when you wake up for the emotional +recalibration that I described in the +nap that had nothing to do with sleep +spindles or even non-rem sleep it +required REM sleep to produce that +benefit so there are certainly many +benefits and we've look downstairs in +the body blood pressure cardiovascular +measures immune Health they all seem to +benefit so at that point everyone may be +thinking of course this sounds good not +to mention the basics which is your +attention your concentration your focus +and your energy all improve by way of +naps even your decision- making you said +decision making yeah even your +decision-making is improved so your +capacity to make the correct decisional +outcomes based on this weight of +evidence that you're facing that's also +improved so almost all areas of +cognition that we've looked at and many +areas of your emotional and mood Health +we've looked at seem to benefit by way +of a nap at that point you're thinking +so then what's the problem the problem +is that when you nap you release some of +that sleep pressure that's been building +up so in the first episode we spoke +about a chemical called adenosine and +the longer that you're awake the more +adenosine that builds up the more +adenosine that builds up the sleepy you +will feel and after about 16 hours of +being awake you should have lots of +healthy sleepiness of adenosine in your +brain to put you asleep and keep you +asleep and when we sleep we are able to +clear that adenosine from the brain so +we wake up after 7 to 9 hours and if +it's been good quality sleep we're +refreshed because we've cleansed the +brain in part of that +adenosine when you take a +nap like a pressure valve on a steam +cooker you just Rel relase some of that +healthy sleepiness that you've been +building up so the the Dark Side of +napping is if you are struggling with +sleep and you suffer from insomnia the +advice is do not nap during the day +because you're setting yourself up for +an even higher probability of failure at +night why because when you nap you +release some of that good sleepiness +that we need to build up for you as +someone who is struggling with sleep to +give you the greatest chance of awai of +sleepiness on your +shoulders so if you are not struggling +with sleep and you can nap regularly I +would say naps are just fine and we can +unpack what is an optimal nap and the +protocol for what napping should +be I would say that's great the only +caveat is make sure that you're not +napping too late into the day and this +is one of the components of the protocol +of how to nap because napping late in +the day is too close to sleep and you +can think of it almost like snacking +before your main meal a nap late in the +day just takes the appetite edge off +your sleepiness so that when it comes +time for sleep you're not as hungry +anymore so just keep that in mind but we +can unpack perhaps the optimal way to +nap if you are going to nap and exactly +the dos and the don'ts of that if that +sounds of somewhat interest yeah that is +uh of immen interest to me and I know +many other people I'm a huge believer in +naps I've always enjoyed um short naps +of about 10 to 30 minutes unless I'm +somehow sleep deprived in which case I +will sleep for an hour or even a little +bit more but I make sure I set an alarm +U really based on advice that you gave +me which was to um first of all decide +whether or not a nap is beneficial for +for for me or for whoever is considering +that um but then to make sure that +however long that nap is zero to 90 +minutes that it not be longer than 90 +minutes because the real goal is to not +disrupt nighttime sleep that's right +which is essentially just a a more +long-winded way of saying what you just +said so how does one determine the +optimal duration of nap um and in +particular to avoid the problem of +disrupting nighttime sleep by napping +but also this uh rather common +phenomenon of waking up and feeling kind +of groggy or even I'm kind of grumpy the +post-nap face uh or we should call the +post-nap expression +right right the P NE what's your P are +do you wake up um in the and for morning +too some people wake up and they're like +that that face and then there's the like +good morning you know and I think people +that wake up with the good morning are +particularly delightful unless you're of +the post Snap expression that is kind of +the the crumpled face and then you just +you don't want to be around those people +right no absolutely +um yeah and this probably relates to +spirit animals and things like that some +people wake up like a like a cheerful +chipmunk and other people seem to wake +up like my Bulldog Costello where it's +you know um jowls still in contact with +the floor yeah so um P I'm trying to +hold it together and not Absol just fall +apart it's brilliant please trademarket +so firstly to your question how to +optimally nap the word optimal is +interesting because +when you people say how long should I +nap what's the optimal nap duration the +question I have back to them is what are +you trying to optimize because once I +understand what you're trying to +optimize I can give you a better +prescription non-medical I'm talking +about here the a better sort of you know +protocol piece of advice for how to nap +I mentioned the study about emotional +faces in part for a specific reason cuz +I told you there the benefit came by way +not of non REM sleep but REM sleep and +in our first episode we said that when +you go through these on average 90minut +Cycles you get most of your non-rem +sleep first and then you'll have this +bout of REM sleep at the end and it +always seems to go that way when you are +a healthy normal person you go into +non-rem sleep and then you go into REM +sleep it's very rare that you ever go +directly into REM sleep there are only +two reasons when that seems to happen +the first is a clinical condition called +noopsy where you can have sleep onset +REM sleep and very rare the second is if +you are horrifically deprived of REM +sleep night after night after night and +I let you sleep then at that point REM +sleep the pressure for REM sleep has +been built to to the point of being +almost just insatiable and your brain +goes straight into REM sleep but with +those two things aside you go into +non-rem sleep first so I brought up the +emotional study of resetting your sort +of mood uh compass +because to get that REM sleep you had to +nap for a longer period of time because +you had to get through the non-rem sleep +first before you get the REM sleep but +let's come back to then assuming optimal +is for most people when they speak about +naps I just want the quick reboot I want +my alertness and concentration which are +failing because I'm staring at the +screen or I just can't concentrate on +the work that I'm doing I want my +alertness and my concentration to be +improved proved I want that sort of +slight boost in brain energy where I +know I can sustain myself for now a +longer period of time and I've got the +motivation which is really in some ways +how I like to think about energy as well +I've got the motivation the drive to +keep going which is just starting to +fail me to get those basic things which +is what most people nap for aim for 20 +minute nap why 20 minutes if I thin +slice the nap duration and and those +Studies have been done where we look at +essentially what's called a dose +response curve I give you 5 minutes of a +nap 10 minutes of a nap 15 minutes 20 +minutes 30 minutes 45 minutes 90 +minutes after 5 or 10 minutes you don't +really get very much you will wake up +and you'll have some degree of improved +alertness and your basic reaction time +may be a little bit quicker but that +Fades very quickly and you don't sustain +that +benefit once you get past about 15 to 17 +minutes now things start to look +different you get these nice benefits +for concentrational alertness and +motivation and those things sustain so +once you wake up out of that probably +really I would say 20 minute nap at that +point you've got some good wind in your +concentration and energy sales for the +brain and that will sustain you +throughout the rest of the afternoon and +into the +evening the benefit of the 20-minute nap +is that you don't get the +PNE trademark Andrew hubman you don't +get that almost sleep hangover so some +people will say it's strange I nap maybe +I'll nap 45 minutes 50 minutes and I +wake up and to be honest Matt I almost +feel worse after the nap than I did +before and I don't understand it it's +something called Sleep inertia +and an extreme version of this is in the +first two hours of your night of sleep +you get a phone call or an alarm goes +off and you wake up and you are just +kind of lost in the ocean you're looking +around at your surroundings you're just +in this groggy State you're half awake +half asleep and you can respond and you +can do things but boy does it feel +miserable and it's almost as though +you're going from the ground floor right +up to the penthouse suite but you get +stuck somewhere in between kind of you +know floor 13 and it's this rough +state if you go out into sleep light +stage one nonrem then stage two nonr and +just before you get into the very +deepest stages of non Ram 3 and four +that starts to happen around 30 to 40 +minutes for most people but by cutting +your nap off at 20 minutes you still get +these nice benefits from a good chunk of +healthy non-rem sleep but you're not +going so far into the cycle so deep into +your nonr that when you wake up after 20 +minutes you're not in that what we call +Sleep inertia phase that sleep +grogginess that sleep hangover phase so +it's a nice benefit that you get all of +these improvements in your brain but you +wake up and very quickly you're back up +to operating temperature and you don't +suffer that inertia now that's not to +say that when you sleep or you nap +longer +you don't start to get more benefits you +do and those benefits are both greater +in their magnitude and sustain for a +longer period of time they do it's just +that you have to understand the tradeoff +that you will suffer which is I will get +more bang for my book and I will get +more benefits but I will in the first +sort of hour or so have to understand +that at that point I may even be +functioning worse than than that which I +did before I even started napping but if +you're patient and you go through it the +rewards on the other side are +significantly better still so that's the +first piece of advice and when it comes +to how to nap I would say the dose and +the timing make the poison and poison is +hyperbole in here it's simply just the +poison being how much sleep and nurs +you're going to suffer so aim for about +20 minutes that's the do the timing +comes back to that which we described +before do not nap too late into the day +so what's the rule of thumb here for a +protocol on average for the average +adult I would say don't nap after about +300 p.m. 20 minute naps sometime between +300 p.m. and if you're struggling with +sleep don't do this at all if you're not +and you're able to get to sleep fine +this seems to be a good ingredient for +the basic return on your investment +again if you tell me what's the optimal +nap duration we need to have a +conversation to understand what is it +that you're going after here what are +the benefits and then I can sort of you +know create a finger Buffet Kaleidoscope +match to what you need and we can think +about the nap duration as a consequence +thank you that's very informative um I +have a colleague at Stanford who's a +Howard Hughes investigator which for +those that don't know is a a rather +elite club of uh academic research they +have to essentially try out for it they +can every 5 years they go up for Renewal +it's it's a lot of money which makes +gives them a greater capacity to uh take +on greater risk uh work higher risk work +um and he's also a member of the +National Academy and he was one of these +people that graduated high school at 15 +years of age one of these phenoms and he +is so religious about his napping such +that when he travels to give seminars at +other schools he insists that they +schedule a nap time for him after lunch +and in his office um you know at between +12:30 and and 1: p.m. he's napping +everyone knows this and um and I mention +this because I think that um oftentimes +people think of the Nappers as the lazy +ones but um his output is um near +superhuman and he attributes U much of +that output uh to the nap not just the +post-nap work that he's able to perform +but his ability to uh just kind of +manage so many ideas he has enormous +laboratory and that's just one example I +think there are examples from sport of +um sprinters taking naps on the you know +on the side of the the track field I +mean so it seems that a capacity to nap +is also something worth considering +because I think many people listening to +this are thinking well I can't nap +should I nap you know um and can one +teach themselves to nap so that's the +question um if one would want to explore +napping and um is that something that +one should even consider doing if you +don't have a propensity to nap should +you avoid it if you want to try naps how +could one teach oneself to nap you just +mentioned earlier uh lying down uh +relates to body temperature body +temperature uh relates to sleepiness and +then as a third question I promise I'll +repeat these if we need to uh as a third +question I'd like to have a little bit +of a discussion about some of the pseudo +naap states that um I certainly am +intrigued by you know for instance just +lying down and I'm doing a progressive +bodily relaxation things like Yoga Nidra +uh non-sleep deep rest which is an +acronym ioin simply to to um make it +clear what I was talking about but it's +very similar to Yoga Nidra um things of +that sort in other words but simply +should everyone think about having an +early to mid-afternoon +protocol to reset their cognition and +their body we call it a nap but does it +have to be a nap and if we're not good +Nappers should we try and if so how +should we go about it yeah so TI your +three questions firstly if you're not a +natural Napper should you start doing it +um if you want to start doing it how +should you do it and then the third is +is there some kind of you know +substitute for a like kind which would +be these Li these I I'd love the +phraseology that you use these Lial +states do they mimic that are they +different to that how should we think +about those the first thing I would say +to point number one if you are not a +natural Napper don't necessarily Force +yourself to be as long as you're getting +the sleep that you feel you need at +night and you feel refreshed and +restored during the day and you don't +have that sort of postrenal drop to the +point of thinking I almost need to nap +during the day there is no pressure +based on anything I've been telling you +for you to start napping nor should +there be any reason that you do start +napping but let's say that you want to +try what would be the right protocol to +improve and increase the likelihood +the best way you can do this is to mimic +nighttime as best you can so wherever +you are if you can shut off the +lights make sure that you can block out +you know curtains blinds if you can't do +that fully and many people won't be able +to develop an IM mask procedure um so +put an IM mask on make sure you block +out noise earplugs you can use a sound +machine if you want and we can speak +about sort of sound machines and whether +or not they're good or bad on sleep and +then you can lie down make sure that you +try to take your shoes off and get under +some kind of a blanket because we're so +Contex cued by having something wrapped +around us called a blanket or a duvet +that to do it without that if you are +not a natural Napper can help you again +that some people will say I can just +kick my feet up on my desk sit back in +my reclining chair in the office and I +can fall asleep that's great but if +you're not a natural person I'm just +trying to tell you things that increase +the probability of that and then set the +alarm I like your idea of making sure +that if you do fall asleep you don't +accidentally go too long and then just +feel miserable so mimic the conditions +that you're trying to get that you would +normally get at night that will increase +the probability mask out noise mask out +light kick your shoes off have some kind +of a blanket wrapping around you that's +probably the best and then time it based +on this sort of post pral drop you will +know yourself everyone has fallen prey +to it you know W it's usually around +about 3 4 p.m. that I do start to feel +this decline or it's around 1 p.m. try +to match it in accordance with that so +those are the first I think two +questions should you not necessarily if +you would like to and I'm not normally +doing it how can you do it the final +point I think is fascinating which is +these alternate states +of conscious brain activity the most +obvious is when we're awake and when +we're asleep those are the two most +dramatic changes in Consciousness that +we experience on a daily basis short of +anesthesia I've become like you very +fascinated by these sort of both +meditative States or these linal states +I think at some point you and I should +collaborate and we should do some work +and really unpack this but the reason I +find this interesting is because I'm +going to guess you are having sleep +likee States but you are not fully +asleep how would I Define a sleep-like +state what we've learned is that your +brain the way it sleeps isn't on mass +it's not as though your entire brain +sleeps different territories of your +brain can sleep in different +ways and what we've also known and +there's some argument even individual +brain cells seem to have a period where +they go into sleep and these individual +neurons will start to show what look +like these beautiful big powerful deep +slow waves in terms of their firing rate +at least in terms of those neurons +firing away I bring this up because if +that means that your brain can have +local sleep rather than Global sleep if +you are in global sleep you're out like +a light you are a sleep but perhaps +these Lial States the reason that they +give these benefits is because you are +still awake not Global sleep so if +you're in global sleep you're asleep but +you're awake so you're not in global +sleep but you may be having local sleep +now using special um setups in my +laboratory we can apply tens maybe +hundreds of electrodes all over your +head and we can map the the sort of the +the different places where your brain is +having sleep in much higher resolution +so rather than a you know 480 DPI movie +on YouTube I'm now in 4K resolution I +can really dismantle what's going on um +analytically in your brain I'm going to +guess that when you're going into these +states and you report coming out of +those states and I ask you on a scale of +1 to 10 how would you rate that as an +experience based on your common +experience the greater the intensity of +the lional benefit and state that you +experienced I'm going to predict is +directly related to the extent of this +this local deep non-rem slow wave sleep +that's happening you're still awake but +some parts of your brain for maybe +seconds of time or maybe even tens of +seconds of time I'm going to bed will be +oscillating in what look like slow wave +sleep deep sleep States and if all I +would be able to look at is that one +part of your brain and that small +cluster of electrodes and someone said +to me is this person awake or asleep I +would say oh they're asleep they're in +deep sleep but then if you slowly reveal +and back out and show me the rest of the +brain and what it's doing I would say oh +my goodness no this person must be awake +but that local territory that District +up there in their brain they were having +slow wave +sleep I think that's what we could find +and that may predict some of the +benefits that you get some of the +productivity energy benefits by the way +I should note that with all of this nap +racket NASA figured this out back in the +1980s they were looking at ways to +optimize their astronauts because when +you are up in orbit depending on what +orbit you're in you are rotating around +the planet maybe 10 and 20 times per 24 +hours so you're seeing 10 to you know 20 +sunsets and sunrises so your sleep is a +total mess and you can safety check +almost everything in terms of Technology +but the one weak Link in a space mission +is this thing called the human being +that's where errors typically happen so +how do you drisk a human error up in +space because if you make an error up +there I mean on the ground not great up +there kind of +catastrophic you can try to optimize +their ability to sleep and their ability +to maintain Focus concentration +alertness and productivity and what they +found was that these naps produced +almost a 20% boost in short naaps 20% +boost in their alertness and almost a +50% boost in their task productivity and +it was so powerful that it translated to +the terrestrial um employees of NASA on +the ground and it became what was known +as the NASA nap +culture and from there on we had what we +called power naaps Power naaps by the +way why are they called power naaps and +you think well just because it Powers me +up it's a good idea but it's wrong it +has a very specific story a fascinating +one two legends in my field David dingis +uh and Mark Rose kind they were looking +at how to instigate +risk mitigation not in astronauts but in +pilots who are doing long haul +flights because the most dangerous +aspect of a long haul flight is when it +is coming down to land and that's when +they can sometimes have these things +called a catastrophic hole loss which is +a euphemistic phrase for a terrible +plane crash and they were trying to say +how could you use nap +strategically to drisk that and improve +their +alertness and they asked a very +interesting question if they can nap for +only a certain period of time because +they have to be at work on the plane at +the for the rest of it when should you +place that nap should you do it at the +start of the long call flight in the +middle or towards the end and most +people would bet like they I think did +it's best to place it at the end when +you're really starting to struggle get +that boost and then you wake up you're +not in sleep in OA cuz it's been brief +and then you're energized for landing +they didn't find that they found that +the most optimal time to nap was early +on in that long haul flight and it +sustained them throughout the rest of +the flight now they took their findings +to the FAA who were funding the work um +and the Federal Aviation Authority here +in the United States and they said we've +got some great findings and we think we +should implement this and we would like +to use a term to help Pilots understand +this and it's called prophylactic +napping and of course there were many +Chuckles throughout the room perhaps +inappropriate and they just said look +you've got to understand our Pilots the +you know kind of alpha male guys and if +you're starting to say you need to +prophylactically NAB it's not going to +be adopted that's a nogo so they looked +around the room because it's an alpha +male culture it's a mostly masculine +culture at that time they said what +could we and there's a lot of beard +stroking and they said I've got it power +naaps it's got to be about power and so +that is where if you've ever wondered +where the term power naaps come from +it's not because it reboosts your power +which it does and boost it back up it's +because there was Chuckles at the time +prophylactic napping I'd like to take a +brief break and acknowledge our sponsor +eight sleep eight sleep makes Smart +mattress covers with cooling Heating and +sleep tracking capacity many times on +this podcast we discuss how in order to +fall and stay deeply asleep your body +temperature actually needs to drop by +about 1 to 3° and in order to wake up +feeling maximally refreshed and +energized your body temperature needs to +heat up by about 1 to 3° eight sleep +makes it very easy to control the +temperature of your sleeping environment +so that it's easy to fall and stay +asleep and wake up feeling refreshed I +started sleeping on an eight- Sleep +mattress cover several years ago and it +has completely and positively +transformed my sleep so much so that +when I travel to hotels or airbnbs I +really miss my eight sleep I've even +shipped my eight sleep out to hotels +that I've been staying in because it +improves my sleep that much if you'd +like to try eightsleep you can go to +8sleep.com +huberman to save $150 off their pod 3 +cover eight sleep currently ships to the +USA Canada UK select countries in the EU +and Australia again that's 8sleep.com SL +huberman the naming of things fascinates +me especially in um the uh landscape of +health and well-being um also um and +that's one reason why um having become a +real fan and practitioner of Yoga Nidra +which I think translates to yoga sleep +which is this process of lying down for +a period of 30 to 60 Minutes Progressive +relaxation this is these are scripts +that are readily available as this is a +a uh age-old practice um in in India um +that is meant to restore mental and +physical Vig Vigor by placing one into +one of these Lial States the um and I +have great respect for the uh ner +tradition um but um sometimes the names +are a separator so people who hear Yoga +Nidra and they think oh it must be yoga +movement and that's of course not true +or they think um that there must be some +mystical component to it which is not +necessarily true sometimes they include +intentions and things like that but +often not so that's why I coin this um +uh phrase non-sleep deep rest which is +essentially maintains the +critical components of Yoga Nidra um but +doesn't include intentions and um has +these shorter uh 10 or 20 minute um +protocols so it'd be um great fun and um +I think very interesting for us to do +that project to explore what are the +brains uh activation States or +deactivation States as the case may be +in these um non-traditional or Lial +State uh practices now um along the +lines of power napping specifically and +the naming of power napping I think it's +more than than just a a um anecdote +because I think it is very important for +people to understand that um that these +protocols these tools that NASA and that +Laboratories have have developed um +often times are are for other purposes +but they translate to a kind of broader +significance and what I'm hearing and +what I'm starting to integrate as we +have today's conversation is that it +seems that there is pretty good reason +to ex at least explore basic sleep right +that that for the non-nappers to to +really think about whether or not they +would like to explore napping as you +mentioned they don't have to and then +for people who are already um napping to +really think about the placement of that +nap uh within the day and the duration +of that nap what you told us a few +moments ago suggests that I should be +doing or anyone that's doing naps or +entering these Lial States like nsdr +might want to shift them a little bit +earlier than uh the period in which they +first become sleepy to take that nap is +that right I mean like so for instance +should I do as my colleague and you know +finish lunch and and lie down for 10 15 +minutes um rather than wait until 2 or 3 +p.m. is that is that something that that +could make a meaningful difference I +think it could and I think it really +again depends on how much of a struggle +sleep becomes in the evening for you if +it is becoming the later that you nap if +your sleep becomes either a more +difficult to initiate in the evening or +maybe you don't have any problems +falling asleep but for some reason when +I look back I'm now starting to wake up +more throughout the night that in part +again it's not just that if you nap late +in the day you struggle to fall asleep +you may not the other consequence that +can happen which is non-mutually +exclusive is that you then stay in not +as deep as sleep and your sleep is more +some more fragile in that sense so the +probability that you will wake up +because because you had the nap so late +in the day is higher in the middle of +the night and then when you wake up like +many of us do and you go to the restroom +or It's Perfectly Natural but the speed +with which you can then fall back asleep +is compromised why because you've +jettisoned some of that sleepiness by +way of the nap and there isn't as much +to take you back down into sleep after +you've woken up so I would just say that +if you are seeing that pattern that the +later napping that you're doing if +you're doing that and again there's no +reason that you need to nap only if you +choose to nap if that's the case then +consider not necessarily obviating the +nap that may not be required just bring +it back earlier take it after lunch see +how things work out do the experiment +and when you do the experiment make sure +that you do what I would describe as the +onof on experiment which is where you're +napping as you normally do and you've +noticed perhaps some problems with your +sleep then do so that's sort of the the +well it's sort of the on off on phase so +then change your nap protocol and move +it earlier so now you've Switched Off +Your Standard protocol and you've moved +on to something different so you're on +your standard protocol and then you come +off it and when you come off it meaning +you go to an earlier nap and you say +gosh things do seem to be better maybe +he he had something there and it does +seem to +improve good but I don't trust that +because maybe it's just a placebo effect +that you you know hear some dulit +British tones and you get convinced that +maybe that would work and you've now +instead after about two weeks of doing +that and things have improved go back to +your original schedule go back on to +your original protocol I'm not as +interested about the fact that things +got better when we changed it I'm +interested in the question do things get +worse when we stop it and so when we +stop the intervention if things got +worse again now I'm I'm believing it a +lot more so just as a tip if you are a +self- tinkerer and you don't have to do +that but if you're idiotic like me and a +scientist and you want to do it with +this city riger that's the way I would +suggest doing it I don't think it's +idiotic at all I think it's systematic +and what you just described is uh both a +negative control and a positive control +experiment so you're you are a scientist +through and +through are there any individuals that +should absolutely avoid napping you know +I'm heard lore of you know um elderly +folks um folks with certain conditions +um you know can't imagine um which but +um I'm sure you'll tell us that for whom +napping is harmful to their health it's +a very I think interesting question +because the strongest evidence comes +back to that which we we've mentioned +before which is insomnia and really the +recommendation there is just avoid naps +it's and what's problematic about +insomnia when you are having such tough +times with sleep at night and you are +just dragging through the day it is +miserable and I am you know I I'm very +protective of my sleep um for the most +part I +sleep pretty well but I've I'm I'm not +immune to the vagaries of sleep I've had +two bouts of insomnia throughout my life +both have been what we call reactive +insomnia reactive to an event or +something happening and I know how just +desperate and hungry you are for sleep +and if it's happening week after week +month after month I'll just do anything +to get sleep when I can and the +Temptation therefore to nap when you are +suffering from insomnia is that much +higher and therefore the advice is that +much harder to adopt but trust me that +is one of the components that we have in +the psychological treatment bucket that +we use for insomnia which is called +cognitive behavioral therapy for +insomnia or cbti for short and you can +just look it up or um on my own podcast +I done a six-part series on on uh +insomnia so I would say try to back away +in that circumstance but you brought up +a another example which is in aging +there I think the evidence is a little +less causal so you have to be more +cautious about recommending the absence +as I was with insomnia of abstaining +from naps but the data has now become +quite strong that when you get past +about 65 years old and you look at +napping behavior in large +epidemiological studies and you say is +there a positive benefit in aging for +napping or is there no benefit at all +and they looked at that because they +thought well that perhaps based on the +work in healthy adults that I've +described that would be good for older +adults not only did they find that it +wasn't good they found that it was +deleterious that napping in older adults +was predictive of worse Health outcomes +and it also seemed to predict a higher +likelihood of early +mortality so at this point we're +thinking well how does that fit with +everything you've been telling us it +comes back to this notion of bad sleep +at night it's probably not necessarily +that napping during the day is bad for +older +adults it's that the Naps reflect a +problem with the night of sleep for +older adults and as we get older +something I didn't mention during +development was that yes we get this +sort of State Lael ratio of 4 to1 of one +part REM sleep four parts non-rem in our +7 to9 hours and I described these +changes in rem early in development I +didn't mention two things about non-rem +slow wave activity first as we go into +our teenage years and we shift our sort +of timing of sleep where we want to go +to bed later and wake up later that's +biologically determined it's not +teenagers fault something happens with +their deep sleep however their deep +sleep starts to do a +different or different action to the +brain that REM sleep was doing as an +infant I said that during infancy we +have huge amounts of REM sleep and were +growing sinapsis syap Genesis and we +wiring up all of those new territories +all of these new neighborhoods with +fiberoptic cable but let's say that +you've now run the experiment across +many years through until teenagehood of +those neighborhoods and you've been +measuring the bandwidth consumption of +each individual house and you've started +to realize well I wanted to create a big +spread across the brain and then I'm +just going to let experience over the +next years time tell me which parts of +the brain seem to enjoy that high +bandwidth and which parts don't seem to +use it very much and as we go through +into our teenage years we go through +something called synaptic pruning where +the brain actually calls and takes away +copses from certain parts of the brain +it seems to be that this change in slow +wave sleep that happens around these +adolescent years is performing the act +of final cortical +maturation that it's downscaling the +synapses and fine-tuning the brain so +you've got this beautiful efficiency and +now you've throttled back some of the +bandwidth from some of those +neighborhoods because they just don't +use it very much and you can move it +over into the territories that are +demanding more bandwidth and net net the +brain is downscaled but it's improved +its efficiency in the sense that those +regions that need it and are working +hard based on what we think this +organism has been doing over the past +you know 13 years that's where we need +to now place our bets but as we get +through into our older years and this +will come back to this issue of napping +don't +worry stick with me here folks um the +reason is that as we're getting older +our sleep de +deines but it's not just all sleep +declines deep sleep declines most +dramatically and we all think of aging +from brain perspective as cognitive +decline that our learning and memory +abilities begin to fade and Decline and +they do but I would argue that a +physiological signature of Aging is that +your sleep gets worse and particularly +your deep sleep what's perhaps +concerning for people listening to this +right now is that that decline in deep +Sleep doesn't start happening in your +60s or your 50s or even your 40s we can +start to pick up that great sleep +decline beginning in your mid to late +30s and then it just decreases and by +age 50 you are down to about 50% of the +deep non-rem sleep that you were having +when you were 17 or 18 by age 65 and +over or certainly by age 75 you are down +to about just 5% of the deep sleep that +you had when you were 17 or 18 which is +a stunning +decline what that means comes back to +the first episode we spoke about the +four macros of good sleep quantity +quality timing and regularity one of the +measures of quality that I described to +you was this electrical quality of deep +sleep the other measure of quality sleep +I spoke about was how consolid ated and +consistent your sleep is versus how +fragmented your sleep is the measure of +Sleep Quality is markedly compromised as +we get older we're waking up many more +times our sleep is much more fragmented +and therefore our sleep efficiency is +worse and we've got this huge decline in +our deep non-rm sleep so no wonder then +when you are awake during the day as an +older adult Your Sleep Quality is so +compr promised at that stage you perhaps +try to compensate by way of napping but +that compromised quality of sleep that +you're having at night is probably the +reason that you start to get sick more +that you have a higher probability of +illness and disease and why also you +probably have a higher risk of premature +mortality so in other words it's the bad +quality of sleep at night that leads to +this behavior that we call daytime +napping in older adults +that seems to indirectly suggest oh my +goodness it's daytime napping that's bad +and that causes these problems when in +fact it's that daytime napping is a +proxy for the bad sleep that's happening +at night and it's really the bad sleep +that's happening at night that is more +directly related to the health and +mortality concerns in older adults so +that's why I think right now as a field +I'm still open to evidence that napping +for some reason that we just do not +understand right now is problematic and +does causally predict worse health and a +shorter lifespan in older adults I think +the best evidence that we have right now +is that it's actually the bad quality of +sleep at night and thus we should not be +necessarily jumping to recommendations +that all older adults should stop +napping I think we need more evidence +and I'm open to both sides of that let's +talk about caffeine uh I've heard the +ter term is it +napino yeah I I I think it um refers to +a practice of drinking some caffeine +then laying down for a nap and then +supposedly waking up um feeling more +refreshed my understanding and you'll +tell us more of course is that caffeine +um is effectively uh an adenosine +antagonist although it's a competitive +Agonist and you'll explain I'm sure um +and napping as you mentioned before uh +removes some of the Sleep pressure AKA +uh wipes away some of that uh adenosine +that's accumulated um both of which +sound great but as you mentioned earlier +there's a warning there as well uh the +warning label on uh both those things +should be that having sufficient +adenosine built up in your brain is one +of the ways in which you feel sleepy at +night and fall asleep and stay asleep +yeah so what's the story with caffeine +how does it work uh to make us feel more +alert and +um what is the rationale for the +nappuccino the nappuccino also known as +the caffeine nap caffeine is a very +interesting compound in relationship to +sleep and wake obviously everyone knows +that caffeine can help you stay awake +it's no coincidence that those two words +that you've used about these chemical +compounds caffeine and adenosine sound +the same it's because the re receptor +that or the receptor systems that +caffeine Targets in your brain are the +adenosine +receptors and you think well Matt was +telling me that the more adenosine that +builds up in other words the more +adenosine that's latching onto those +adenosine receptors in your brain the +sleepier that you feel and I'm telling +you that caffeine works on those same +receptors that doesn't make sense +caffeine if it's working on those same +receptors should increase your +sleepiness it doesn't because it when it +binds onto those adenosine receptors +those welcome sites in the brain it +simply blocks them it doesn't deactivate +them nor does it activate them it simply +blocks them so think about it almost a +little bit like um a room that's full of +chairs and at some point these adenosine +which is one collection of people with +the name badges of adenosine they would +normally like to come in and start +sitting down on those seats which are +the adenosine receptors and as they sit +down on those seats you're building up +this signal of sleepiness well caffeine +which is another group of people with +caffeine badges they race into the room +and they start to hijack the seats and +they start to sit down on them and all +of a sudden adenosine can't find any +seats to sit on so your brain is still +flooding that room with adenosine so the +adenosine is still building up but the +reason that you don't feel sleepy +anymore when you've had a shot of +caffeine is because caffeine is raced in +it's latched onto the +receptors and it has essentially hit the +mute button on your +sleepiness so now your brain was +thinking gosh I've been awake for about +13 or 14 hours I'm starting to feel it +I'm just going to take a quick espresso +shot and you get that you don't think +well hang on a second you know 20 30 +minutes later I don't feel as tied +anymore why it's not because caffeine +came in and removed the adenosine it +didn't caffeine has come in blocked the +sights but the the adenosine is still +building +up and then at some point the caffeine +wors off and therefore not only do you +go back to the same level of Denine of +adenosine that you did 2 hours ago it's +that plus the additional 2 hours of +adenosine that has been building up and +what you experience is something called +a caffeine crash and now you need even +more caffeine not just to get you back +to where you were but to recover the +crash that you've had and go +further caffeine in relationship to the +caffeine nap though the +napino is relevant because of its +timing caffeine has an instigating +action of around uh 12 14 to 17 minutes +so when you come through in the morning +and you grab your first cup of coffee +and within the first four or five +minutes you you say I just I just feel +better I've just had a couple of sips +I've had half a cup of coffee and I +already feel better I just needed that +if it's within the first five minutes +that you're experiencing that it's got +nothing to do with the caffeine because +the peak plasma concentration of your +caffeine is not going to arrive with you +until about you know 12 to 17 minutes so +why do you feel better some of it is +Placebo because you're smelling the +coffee and you associate it with the L +it's really not that though or or um +when you say Placebo I also wonder +whether or not it's possibly a a +conditioned effect you know like a +pavlovian thing because the smell of the +coffee the taste of the coffee the the +hum of the machine the walking into the +cafe +to to um and ordering it from the +Barista also creates an anticipatory +arousal like here the the alertness is +coming and in that anticipation there's +its own form of alertness I think that's +that's certainly a big component of it +the other component however if you look +at the data is that it's got nothing to +do with the caffeine in that moment it's +the temperature that most people take +their caffeine warm either it's tea or +it's coffee or it's perhaps something +else that Andrew hubman would drink but +many people yamate since since I was 5 +years old I don't I don't know if I +should have been drinking uh caffein +yerbamate so young maybe even four years +old there's a photo of me on my +grandfather's lap drinking out of the +mate gourd half my family is Argentine +and um so I was caffeinated from a young +age this brain developed in a +caffeinated millu this explains so much +about what I've known of you over these +no I'm kidding you um so um but we need +to speak later no so what's interesting +about that is it's the +temperature and I told you in the first +episode that we need to cool down +to stay asleep but we need to initially +warm up to fall asleep because warming +up at that moment I was telling you is +warming up at the periphery a warm up to +cool down to fall asleep so you need to +warm up to cool down to fall asleep then +you need to stay cool to stay asleep and +then you need to warm up to wake up the +warming up to cool down to fall asleep +is not warming up in the middle deep +core of your body it's about warming up +the hands and the feet and the head to +dissipate the heat hence warm up the +outer surfaces to cool down the inner +core to fall asleep but then I told you +you have to warm up to wake up and when +we take a hot drink in the morning +usually caffeinated the change in your +core body temperature can happen with +within a handful of minutes so the +initial benefit that you get from the +hot cup of coffee in the morning or hot +tea is from the temperature rise and +then you get this beautiful second kick +from the caffeine itself and that +caffeine can then sustain for a longer +period of +time so we mentioned this problem with +napping that even at 25 or 30 minutes of +a nap you wake up with that kind of +grogginess that sleep +inertia and what however if I could give +you the benefits of a nap and have you +come out of the nap with zero sleep +inertia and that's what some folks +started to cleverly think +about what if I could look at the timing +of the optimal nap maybe 20 minutes and +think about the timing of when Peak +plasma concentration of caffeine emerges +and I told you really starts to kick +into gear around 17 minutes and it's in +full swing by 20 what if I was creative +I'm going to withhold from saying +idiotic enough but creative enough to +get into bed just before I turn the +light out for my nap in the afternoon I +Swig a quick +espresso light goes +off I close my eyes eye mask earplugs +and I'm going to drift off fine because +the the caffeine is not going to kick in +and for another 17 20 minutes perhaps at +its full threshold so now you you fall +in to sleep and you're going down into +sleep and if you perhaps don't make it +too large in terms of its serving the +temperature change is not going to +affect you in a negative way and then +just as your alarm clock is about to go +off after 20 minutes you're on the +beautiful ascending swing of upward +plasma concentration of caffeine and you +get ejected out the other side with both +the benefits of the nap together with +the benefits of the caffeine so you get +your cake and you can eat it too you get +the nap absent the Sleep inertia and +hence this created what we call the +caffeine nap I love it the nappuccino +the the nappuccino um maybe I'll give it +a try uh this is the first time I've +ever heard the um the rationale and the +the the fine structure of the nappuccino +but it makes sense um uh at a logical +and mechanistic level I have to ask is +there anything besides caffeine and +sleep that can clear +adenosine you know can exercise clear +adenosine can uh cold shower clear +adenosine I mean and I understand that +there are a bunch of competing +mechanisms in the body like presumably a +spike in norepinephrine or adrenaline or +both is going to impact the adenosine +system I I once heard a great quote um +from a former uh +member of the National Academy of +Sciences a brilliant guy he said you +know a a drug is a substance that when +injected into an animal or a human +produces a scientific publication +meaning meaning it is it is rare to find +a paper that doesn't see some effect of +some drug especially on sleep I'm told +as I recall if you put aspirin REM sleep +into PubMed you're going to see some +effect on REM sleep people take aspir +pretty much any substance that one takes +is going to to alter um some feature of +sleep or of wakeful States if one is +looking with a fine enough uh instrument +or is that an overstatement no I don't +think it is an overstatement and it +comes back to the first episode where we +described the complexity this incredible +beautiful physiological ballet certainly +one of the recommendations when people +say I get this afternoon this post +prandy will drop in my alertness what +can I do I say you could nap but another +way is just get outside and walk around +be physically active some of that has to +do with the fact that you'll probably +get some daylight and daylight can be a +stimulator of alertness as long you've +told us and educated us on we also know +that physical activity by itself can +increase the amount of endorphins and +dorphin and those are wake promoting but +none of those are really necessarily +going to be altering adenosine they're +simply overriding the adenosine that is +still building up it really does seem to +be for the most part at least as all +that I know it's only sleep and +particularly non-rem sleep that has the +capacity to or give the brain the chance +to remove that adenosine now what could +be interesting I think is two +circumstances one is where your brain +becomes less metabolically active for +another reason and I told you that it's +not joring it's not as though during +deep non-rm sleep that there is some +special pulsing cleansing mechanism for +adenosine there is a cleansing system +called the glymphatic system which +removes the toxic metabolic byproducts +of the waking day wakefulness in some +ways is biochemically low-level brain +damage and sleep is sanitary salvation +in that regard knew um but which is +again it's humoristic and it's it's it's +going too far but it makes a point the +idea here however is that it's not that +there is a special system that is +removing the adenosine during deep nonm +sleep it's just that your brain is less +metabolically active and therefore it's +not producing as much adenosine so the +natural mechanisms that are always +occurring in the background to be +clearing adenosine and degrading it +simply get the chance to do that just as +effectively as they have but you're no +longer working against the opposite tide +that is growing the adenosine now the +adenosine increase has dissipated +because you're no long longer +metabolically active during deep sleep +and you get the chance to cleanse it all +of which is to say therefore that and I +think that would mimic that such as for +example anesthesia my guess is that you +probably do jettison some sleep pressure +when you are in +anesthesia I also think that these Lial +States non sleep deep rest could be a +fascinating territory there because at +that point I'm going to guess and we'll +be able to see with the e G and we may +also be able to do some Imaging +depending on how we you and I design the +study to look at what changes in the +brain in terms of its activation State +my guess is that if it does put you into +something like slow wave activity +patterns that means that those +territories of the brain are +metabolically less active and that +allows the brain to dissipate the +adenosine so to your point I don't think +things like necessarily exercise or +light change adenosine level +they do give a nice alertness benefit +for other reasons but is there an +alternative way of dissipating adenosine +yes I think anything that mimics a non +or a less metabolically active brain +could produce these beautiful adenosine +benefits thank you for that this brings +me to a question about the period +immediately after waking from the +nightly bout of sleep um I've been uh +touting the benefits of delaying one's +caffeine intake by 90 to 120 minutes +after waking there's a little bit of a +misconception out there I think people +um ran with the ball uh assuming that I +was mandating this or think or +suggesting that everyone should do this +and that's simply not the case uh I +actually wake up and I'll hydrate and +drink caffeine very close to waking if +I'm going to exercise soon after yeah um +which I often do um but I've experienced +and I know others um have experienced if +they are not going to exercise +immediately or they don't need caffeine +to exercise for whatever reason I've +heard these people exist I'm no such M +mutant um that delaying their caffeine +intake by 90 to 120 Minutes in some +cases can offset the afternoon crash now +I want to be clear some of that may be +offsetting the afternoon consumption of +more caffeine because by delaying your +caffeine intake in the morning then +perhaps there's less of an incentive or +requirement to drink caffeine in the +afternoon and all of which dominoes to +as we'll talk about more in the series +to better sleep at night because you +you're not ingesting caffeine close to +bedtime but at risk of taking a massive +tangent here's what I'd like to know +based on what you just told +us if +indeed +sleep and +lower metabolic activity in certain +brain regions can help reduce adenosine +levels in the +brain one could imagine that upon +waking it is either a step function from +okay you know let's say at um 5:45 a.m. +somebody is asleep and adenosine is +still being cleared away because they're +asleep and then they wake up boom does +adenosine clearance immediately stop +well for people who have that um +crumpled face uh grogginess um and they +wake up at 5:45 maybe even by way of +alarm although we don't uh suggest that +right and they stagger into the kitchen +and um ordinarily they'd make their cup +of coffee but they're in a pseudo sleep +state yeah so it stands to reason that +they're still clearing adenosine now if +they are to drink caffeine right away +then they're as you pointed out going to +block those adenosine receptors and +there's going to be a continued buildup +of adenosine as opposed to a clearance +of adenosine so this was um part not the +entire reason but part of the rationale +for suggesting that people at least +explore delaying caffeine slightly and +then there are things like the cortisol +rise and Etc but um does that kind of +framework at least make logical sense +that doesn't mean it would hold up in a +randomized controlled trial but given +that we're talking about essentially +zero risk protocols here um what are +your thoughts on that I think it is good +advice for people to test and it's good +advice for two reasons the first is that +which you describe in some ways by +taking caffeine on early and masking +that +adenosine also caffeine can make your +brain more metabolically active which +means that you're going to build up more +adenosine during the day which means +that sleepiness is going to arrive +earlier which means that perhaps that +postprandial drop is going to be you +know harsher and you're going to perhaps +then need to self-medicate with more +caffeine to and so goes the Vicious +Cycle so I think that's one thing to +keep in mind I think that's one +hypothesis I think the second hypothesis +for me or the second reason I would +advocate for that is if you've been +using caffeine that way for a long +period of time you may also be +masking the quality of your sleep +because you wake up you immediately +medicate with caffeine and you are alert +you're awake and you think well I +looking back on my night I'm awake now +after my caffeine and now is the +important part of that sentence I'm +awake now so there's nothing wrong with +my sleep is that true maybe it is maybe +it's not maybe if you abstain from +caffeine through and you have to get +through the detox period it's not going +to this is not the right test +immediately but do it for about two +weeks and then at that point once you're +free from the detox and the withdrawal +now you're in a somewhat naive state +where you're taking your caffeine on I'm +telling you to stop caffeine you're +taking it on at 11:00 after you've woken +up let's say 7:00 in the morning at that +point we've now got this nice Clear +Window that has been consistently +happening between 7 to 11: in the +morning and I'm going to ask you now do +you feel rested restored and refreshed +and can you operate with cognitive +acumen and +skill in those first morning hours now +don't forget we've got to get past the +natural sleep and Heria period in the +first 90 minutes but after the first 90 +minutes of waking up absent of caffeine +let's say by 900 a.m. in the morning are +you functioning well because if you're +not and you still think you know what I +don't feel restored by my sleep I feel +unrefreshed I want to then start asking +you let's take a look at your sleep and +let's see how we can get you to a more +refreshed state +and by using caffeine first thing in the +morning you don't give yourself the +chance to test whether or not +subjectively you sense your sleep is +good quality now you don't need to do +this forever you can just do a test for +a month and be asking that question and +if all is clear after you've got through +withdrawal and you've got past the first +90 minutes after waking up and you tell +me now in this more caffeine naive state +in the first few hours I feel rest I +feel refreshed I feel restored by my +sleep then that's great we don't need to +be concerned about your sleep so that's +the second reason I like it because it +gives you the opportunity to test out +whether or not your sleep is of good +quality or not I should also note by the +way that I mentioned I've changed my +mind on caffeine and its use and this +comes back to I just raise it because +you had said I made this suggestion and +it wasn't binary it wasn't dictatorial +you don't have to to do it I wasn't +saying that everyone needs to do it and +in fact even I will you know tweak my +schedule if I'm doing one thing in the +morning I will take on board caffeine +fairly soon if I'm not I will hold +off I came out the gate when I first +published um a book and it and I was +very dictatorial about it I and I was +very mono I was very binary you know it +was sleep is absolute and it's +it has to be this way and no other way I +was not in favor of caffeine and I was +telling people about the dangers and +there are dangers to your sleep and we +we can speak about those but it was a +little bit too +heavy-handed I've changed my mind for at +least two reasons +first that's not the way Society works +or people live so there's no amount just +like technology in saying leave your +phone outside of the room for 2 hours +before bed and don't check it for the +first 4 hours that that Genie is out the +bottle so the reason I have changed my +mind on caffeine is because if you look +at the data on on caffeine it's stunning +for +Health it on almost every metric that we +can measure drinking some degree of +caffeine is beneficial now there is a I +knew it there is a U-shaped function to +this which is once you get past sort of +three or four cups of coffee then you +start to go in the downward Direction +and things aren't so great the +contradiction however was that I was +telling people caffeine not good for +your sleep and sleep by the way is +wonderful for Health it transacts all of +these benefits that we have and will +discuss in this series but then you +compare that relative to caffeine and +caffeine transacts many of the same +health benefits so how can you explain +that Mr sleep +scientist well if you look the the data +is very clear it's not the caffeine +that's the benefit most people take on +board caffeine by way of a cup of +coffee and the Coffee Bean is Pack full +not just of caffeine it contains a +whopping dose of +antioxidants and because of our +deficient Western diets were so absent +of these +antioxidants that the humble cup of +coffee has been asked to carry the +Herculean weight of our antioxidant +needs on its shoulders so no wonder it +by itself carries such a strong Health +signal because it's providing you with +this wonderful dose of antioxidants in +addition to caffeine case in point if +you look at decaffeinated coffee you +still get the antioxidants but now now +you don't get the caffeine and lo and +behold you get many of the same health +benefits it's not the caffeine it's the +coffee itself so I think that is a a +perfectly good reason to justify +caffeine but again just like naps the +dose and the timing make the poison if +you're not someone who's sensitive to +caffeine then having a couple of cups of +caffeine and trying to step away from +the use of caffeine I would argue +somewhere between 10 to 12 hours before +you expect to go to bed depending on +your sensitivity and it is different +across people and we know that it's +genetic there is a specific um what we +call polymorphism which just means A +variation in a particular Gene and if +you look at variations in that it will +predict whether you are someone who is +very sensitive to caffeine or not very +sensitive to caffeine and it comes down +to how quickly you can essentially +metabolically remove that caffeine from +the system so if you know that you're a +very sensitive person I would probably +argue try to stay clear maybe 12 to 14 +hours if you're someone who is not as +sensitive then you could maybe go to 8 +hours the danger is for people who say +look I'm one of those people who is you +know really just not sensitive to +caffeine at all and I can have an +espresso with dinner and I fall asleep +fine I stay asleep fine so it's really +not a problem for me I would say that +that that may be true but the inherent +danger here is that and we've done these +studies if I give you a dose of let's +say 200 300 400 milligrams of of +caffeine in the hours before bed which +would be a large you know strong cup of +coffee or you know two espresso with +dinner some people can fall asleep and +some people stay asleep but the amount +of deep sleep that they have is +compromised in fact it can drop your +deep sleep by up to 20% now the danger +is that you wake up in the morning and +there was no signals in your sleep that +said you had problematic sleep because +you're not aware of how much deep sleep +that you had that's the reason that I +think you know sleep trackers can be +helpful in some ways but you then wake +up and you don't feel as refreshed and +restored but you don't remember having a +hard time falling asleep or staying +asleep but now you find yourself +reaching for three cups of coffee to +wake up in the morning rather than the +standard two and so goes the Vicious +Cycle +so and also you see an interesting +interrelationship we did a recent study +we just published in Wall Street Traders +it's not just caffeine use it's also +about alcohol use in the evening that +people who overmedicate with caffeine +during the day they then need something +to bring them down at night and the +principal depressant agent and +depressant not in the sense of +psychiatric depression but in the sense +of brain neural activity depression is +is alcohol so you get this classic cycle +of uppers and downers I need my uppers +during the morning my caffeine and I +need my downers at night to lull me into +sleep and it's this really interesting +trade-off which we we saw in these Wall +Street Traders so coming back to the +notion of caffeine though I am favorable +of it in terms of its health benefits I +think it's very very clear just be +mindful of the dose and be mindful of +the timing dose try to not exceed about +three cups of coffee timing understand +your sensitivity there are certain +genetic tests if you really want to get +nerdy that will tell you if you have +this sensitivity or not but you will +probably know it and therefore just say +okay I'm not that sensitive I could +probably go 8 hours or as close as 8 +hours before sleep or 10 hours if you're +very sensitive 14 15 hours and keep it +to one cup um so those are the ways that +I would see moderating caffeine and +changing my my mind on caffeine which +just comes back to your point where you +were saying I made this recommendation +about caffeine I want to make sure I +modify that so people don't get confused +I certainly um needed to make a +modification to my stance on caffeine so +thank you for letting me say that which +is a long uh winded way of of getting +around it but does that help a little +bit that does help it um very much thank +you for that um addendum to the +legislature +[Laughter] +okay so you told us about the power nap +and you've told us about the caffeine +nap the so-called napino yeah what are +some other types of naps that can be +beneficial for Sleep awake cycles and +alertness so you can think about the +caffeine nap as trying to amplify it +sort of a nap plus as it were but to +your question the study that comes to +mind there was a brilliant investigation +Herculean in its study design from a +great sleep research group out in Japan +and they asked okay the nap is good the +caffeine nap may be a little bit better +but can we go +further um and so they designed a series +of studies they had five different +experimental groups and they tried to +basically create a stack a stacking +system they had across the 5 groups +there was a non naap group that's the +control then there was a nap group then +there was a nap plus caffeine group then +there was a nap Plus Cold face and cold +handwashing immediately after you wake +up I'll come back to explain why that we +think that works and then the final +group was a group that was a nap plus +bright light and again thank you uh me +offering this as the general public to +you Andrew hubman for for your light +Revolution so it was bright light at +2,000 looks immediately afterwards so +they had five groups again there was no +nap group nap group nap plus caffeine +nap plus cold hands and face washing nap +plus immediate brightlight the cold +hands and face washing is interesting I +told you before that there was this +three-part story to to the sleep wake +equation that you need to warm up to +cool down to fall asleep stay cool to +stay asleep warm up to wake up and I'm +saying warm up to wake up but use cold +water on your face and your +hands don't forget that warming up when +I say it in the morning is warming up at +the central core of your body you +reverse engineer what you did in the +evening I said warm up to cool down to +fall asleep so you warm up the periphery +to release the blood from the core and +you cool down well the reason that they +use cold hand and face +washing was because that's this vascular +surface it's the place where we can +modulate temperature quite quickly the +cold water on the face and the hands +therefore caused Vaso +constriction the the vessels and the +capillaries there they all scrunched up +and they force the blood back down into +the core of the body so the core body +temperature increase a little bit now +you also get a bit of an adrenaline shot +when you're splashing very cold water on +your hands and your face so there's some +of that too but that's the justification +so what they find firstly they were +measuring different aspects of your +cognition and your mood and your +sleepiness those were the outcome +measures to assess how did these five +different experimental groups change and +you can imag I mean this is I don't +think I would ever take on a study where +I'm doing five nap groups all within one +study it's bloody amazing so they did +the nonap group and then compared to the +nonap group The Nap group got a +wonderful benefit just as we described +and they showed benefits in their +alertness in their cognitive performance +and also they showed a reduction in +their sleepiness so Point number one on +the scoreboard for a nap then they did +the nap plus the +caffeine and sure enough you got an +added benefit to that which you already +obtained from the nap now it was nowhere +near as sizable as the benefit from the +nap so the addition of caffeine does +give you some nice benefits and I've +used this before when I've worked with +sort of professional athletes we do +instigate these nap um these caffeine +naps when needed so it did give a nice +benefit but then when they looked at the +nap Plus Cold hand and face washing and +the nap plus the bright light those also +added something to The Nap benefit now +they didn't do the sixth Group which is +really what I'm going to do some hand +waving about which is the full St stack +full fat method where they said okay +you're going to do nap plus caffeine +Plus Cold hand and face washing plus +bright light but if you were to put +those together my thought is that +they're probably additive rather than +simply just you know netting each other +out which means that if you really want +to not just do a nap or a nap plus which +would be the the Caffe nap but the nap +plus plus version you can lean into this +study and the protocol there would be +you get into bed you have your espresso +shot before you turn the light you Swig +it go down set your alarm for 20 minutes +you wake up the caffeine is kicking in +you get over the inertia you go straight +out cold hands cold face by way of cold +water and then you get immediate +daylight for 5 to 10 minutes outside and +at that point you're really in a +supercharged state so that's if you just +because I know there's probably going to +be some audience members who are willing +to give this a try or who really want to +optimize don't give me you know what is +good give me the extreme very best +that's the only suggestion I would have +based on that data I love it and +actually what you just described could +easily be um translocated to the uh the +period after uh waking from the nightly +bout of sleep although one wouldn't +ingest caffeine prior to waking up for +obvious reasons um but it would make +good sense to me to uh wake up obviously +get sunlight in one's eyes um splash +some cold water in one's face or hands +or get cold shower cold plunge um +caffeine or delay caffeine I mean it's +essentially the same set of tools and I +think it really um points to the fact +that circadian rhythm clearance of +adenosine uh temperature modulation and +of course the the way in which these +interact um are really the the levers +and and knobs to to modulate wakefulness +yeah it's it's so it there are I think +we've gone over this notion of naps but +there are ways that you can try to +manipulate the nap system still and +there are ways that you can manipulate +it even further but I like what you're +saying because it just comes back to the +fundamentals let's let's forego the the +nap conversation just go back to the +morning routine you're absolutely right +and think about the cold water and +warmart my guess is that very few people +when they go to bed +they wash their face and their hands +maybe they're probably not washing it +with cold water before they go to bed +correct they're going to be washing it +with warm water why don't they do that +and they just say well why would I +Splash cold water on my face you know +probably wakes me up you ever thought +about why it wakes you up part of it is +the you know the shot of activation but +the other part is Thermo regulation and +the opposite is what what you want to do +if anything you want to be warming your +hands and your feet and that's exactly +what you've always done you've always +medicated your sleep onset by using warm +water on your face and your hands +several times during today's discussion +we talked about polyphasic sleep um and +the different types of polyphasic sleep +that we covered are I wouldn't say +conventional but they're um conventional +is what are some of the more um esoteric +or let's call them high performance Pol +polyphasic uh strategies uh for sleep so +we've spoken about polyphasic sleep in +the natural way it occurs which is +during infancy and sleeping like a baby +means that you're sleeping in a highly +polyphasic way but probably around about +the late 1990s 2000s with the emergence +of the biohacker movement and the +Quantified +self-movement there started to become a +lot of chatter online about this notion +of polyphasic sleep and here no longer +are we infants we're now adults but +we're engaging in a pattern that is +highly +polyphasic polyphasic sleep simply by +definition again means that you're +having multiple phases of sleep within a +24-hour period And there are different +strategies so the way polyphasic sleep +in adults works is that you take the +24-hour period and you think about it +like a pie chart and then you start to +slice that pie up into these quadrants +when it comes to polyphasic sleep the +goal is to put insert multiple phases of +sleep around the 24-hour clock rather +than one single phase but the thinness +of those slices of the pie are very thin +leaving large thick slices of +wakefulness in between the notion that +being that if you were to sort of just +intersperse Little soupson of sleep in +terms of these little thin slices of +sleep you can increase the amount of +time that you're awake and you can +increase all of the benefits of a wake +so if you look at the there is a website +I think it's called the polyphasic +society and there it's not a scientific +Society like the you know psychological +the American Association for uh +psychology or medical um American +Medical Association or British medic +it's not one of those ratified certified +scientific or medical it's just society +that lives online which is great and +they make claims to suggest that +polyphasic sleep can improve aspects of +your mood it can improve aspects of your +productivity it can maybe even improve +aspects of Health I think sometimes +there are claims that it can help with +lifespan and there are a number of +different schedules that they will +describe to you and that you can find +out there of polyphasic sleep there is +is the first one that probably people +have heard of is called the uberman +schedule and by the way there is no h at +the start of that it is simply you I +know it's not this man sitting across +from me who has anything to do with this +schedule and after we discuss the data +he will um reassert that very same fact +then there's something called the +Everyman shedule and then there is the +triphasic schedule and there's lots of +different other flavors of this the +differences between them are in how you +split up that pie chart and how much you +assign to little thin slices of sleep +versus longer periods of wake and how +many of those you insert but they all +follow the same pattern if you look at +the literature however it didn't begin +with the biohacker movement the first +description I can find in the human +record comes from Time Magazine an issue +in +1943 and they describe the protocol of +at the time a fantastic very interesting +designer a guy called book Minster +Fuller and he created a design principle +and that design principle was called the +daxian principle the daxian principle +was principally used initially to build +unique building structures and it uses +this notion of different sort of almost +spokes that interconnect in a central +Hub that create a self-supporting +structure are the most obvious have you +ever been to one of those geodesic domes +and inside you go in it's like a +botanical garden and it's all tropical +despite you being in a let's say being +in England in London and is beautifully +tropical inside of that that structure +that sort of latis structure that comes +in part from his Design This was the +daxian principle and he scaled it to +different things the daxian car the +daxian house the daxian Dome it +fascinating +but he was no fan of sleep and he saw +sleep as a rather significant waste of +time when just like the rest of his +daxian principle he could be harnessing +more efficiency out of the system with +less structure and here less sleep +structure inserted into his 24-hour +period so he was the first one to +describe his schedule and it was called +the daxian schedule of polyphasic sleep +so it may have been a practice earlier +in the record but that's the earliest +one I can find so let's come back to the +claims of polyphasic sleep that it could +improve let's say your mood or your +cognition or your productivity or your +health the a group of scientists at +Harvard some of my old colleagues um +from Harvard they looked at all of the +literature on all of the stes that were +polyphasic like or testing this +claim and the first thing that they +found was to their claims of improved +cognition productivity mood as well as +health they found no supportive evidence +that polyphasic sleep was helpful then +they turned the tables and they said +well could it be hurtful and in fact +that's exactly what they found firstly +the total amount of sleep that you get +on any one of those schedules is +decreased significantly now of course +that's the goal the quality of sleep +that you get though is miserable your +sleep efficiency even when you're having +these short periods of time especially +during the waking hours is very poor +it's not a type of even short sleep that +you would wish for third they found that +it would reduce your REM sleep amounts +so that was the first set of findings +your sleep is no better if anything it's +significantly worse and then they +started to find that there were +significant impairments in many of those +things impairments in cognition in +judgment making and decision- making +impairment in mood and some aspects of +impairment in metabolic Health +particularly glucose +regulation so when it comes to +polyphasic sleep sleeping like a baby if +you're an adult seems to be a rather +unwise piece of advice now yeah I mean +it probably goes along with eating baby +food drinking breast milk and um and uh +having somebody else uh clothe and +change you as an adult it's probably uh +not advisable +it doesn't seem to be at least supported +by the data and again I want to be so +careful here and you're very careful too +I'm not here to necessarily tell anyone +absolutely how to live their life I'm +just a scientist and all I can do is +give you the information just as you do +and then it's up to you to make the best +decisions that you wish to make all I +would say is that I would hope that as +long as you're not hurting yourself and +harming your health and you're not +hurting other people then and it makes +you happy then I say whatever it is in +life good luck I I embrace it I always +say uh do as do as you wish but know +what you're +doing and don't hurt yourself or anybody +else can you get me that T-shirt and I +will wear it five days through Tuesday +so here in this regard though I would +say the evidence would suggest that +maybe you're compromising your health +and your Wellness but that's your choice +voice and I understand it so again no +judgment to the question however of as +long as you're not hurting other people +here I would say that there is a pause +of a caution because what we know is +that when you're not getting sufficient +sleep I described all of the health +consequences in the first episode +there's another danger here which is +road traffic accidents and we describe +these micro sleeps that happen and why +car accidents that are caused by +sleepiness can be so catastrophic +there's a very interesting study that +was done where they looked at people +getting less than 6 hours of sleep for +several nights and they put them into a +driving simulator and they asked what is +the probability that you have a crash or +an off-road event and sleeping less than +6 hours a night resulted in a 30% +increase in you getting into a car +crash now the AAA release some data +showing that when you get down to 5 +hours of sleep there is I think it's +something like two Three Times Higher +likelihood of an accident based on real +data and then when you were on 4 hours +of sleep it was close to a 10 times +greater risk so in other words the less +and less sleep that you get it's not a +linear increase in your risk of a car +accident it's an exponential increase so +I bring this back to polyphasic sleep +because I don't know you know think +about that 30% study let's not go to the +extreme just less than 6 hours of sleep +if this evening you call a taxi and it +turns out two taxis turned up and +outside of your door I said look one of +these two ta you can choose either one +of them but I'll just tell you that one +of these taxis has a 30% higher +likelihood of getting in a crash +relative to the other and it's this one +on the right which would you like to +pick which would you like to put your +wife and children in to S it's very +obvious so I rais that question just to +be mindful no one would wish to cause +harm on someone else to C carry the harm +of someone else by way of your own doing +on your shoulders for the rest of your +life is not one I would wish for and +it's not one that you would wish for +that's the only cautionary note but +other than that I would say you know +sort of live life to the full well that +brings us to the conclusion of yet +another incredible Voyage into the +landscape of sleep most notably on the +different phases monophasic biphasic and +polyphasic sleep +and naps and caffeine and all of their +interactions these are such important +topics at the level of Concepts the +level of mechanisms and as you've also +beautifully described at the level of +protocols that is actionable tools that +people can apply so thank you ever so +much Matt for taking us even further +along this Voyage I'll just remind +people that episodes one and two of this +series that U Matt is uh so generously +providing information about sleep for us +are out and those can be accessed +through links in the show note captions +um those fill in yet other mechanisms +and aspects of sleep and I'm also +particularly excited for the fourth +installment in this series coming up +about the relationship between sleep +memory and creativity so just incredibly +important topics relevant to everybody I +also just want to make note that I +really appreciate you highlighting some +of the develop velopmental shifts that +occur with sleep I often get questions +about um you know sleep in children and +babies and uh elderly adults as well as +um all the ages in between and you've +just um built this incredible tapestry +of of information for people to think +about and act upon should they choose so +thank you Matt ever so much and I look +forward to episode four Andrew thank you +it is such a privilege and it remains +just my absolute Delight to be here with +you thank you thank you for joining me +for today's episode with Dr Matthew +Walker to learn more about Dr Walker's +research and to learn more about his +book and his social media handles please +see the links in our show note captions +if you're learning from and or enjoying +this podcast please subscribe to our +YouTube channel that's a terrific zeroc +cost way to support us in addition +please subscribe to the podcast on both +Spotify and apple and on both Spotify +and apple you can leave us up to a fstar +review please also check out the +sponsors at the beginning and throughout +today's episode that's the best way to +support this podcast if if you have any +questions for me or comments about the +podcast or topics or guests that you'd +like me to feature on the hubman Lab +podcast please put those in the comment +section on YouTube I do read all the +comments on many episodes of The hubman +Lab podcast we discuss supplements while +supplements aren't necessary for +everybody many people derive tremendous +benefit from them for things like +improving sleep for hormone support and +for Focus to learn more about the +supplements discussed on the hubman LA +podcast go to live momentous spelled o +us that's Liv mous.com huberman if +you're if you're not already following +me on social media I'm hubman lab on all +social media platforms so that's +Instagram X LinkedIn Facebook and +threads and on all those platforms I +discuss science and science related +tools some of which overlaps with the +content of the hubman Lab podcast but +much of which is distinct from the +content covered on the hubman Lab +podcast so again it's hubman lab on all +social media platforms if you haven't +already subscribed to our neural network +newsletter our neural network newsletter +is a zeroc cost newsletter that provides +podcast summaries as well as protoc +calls in the form of brief 1 to +three-page PDFs that 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