text,label,Disease "They include: Irregular or skipped periods, which might be present for years or develop after a pregnancy or after stopping birth control pills Difficulty getting pregnant Hot flashes Night sweats Vaginal dryness Dry eyes Irritability or difficulty concentrating Decreased sexual desire When to see a health care provider If you've missed your period for three months or more, see your health care provider to determine the cause. You can miss your period for a number of reasons — including pregnancy, stress, or a change in diet or exercise habits — but it's best to get evaluated whenever your menstrual cycle changes. Even if you don't mind not having periods, it's advisable to see your provider to find out what's causing the change. Low estrogen levels can lead to bone loss and an increased risk of heart disease.",798,Premature Ovarian Failure "chills,vomiting,high fever,sweating,headache,nausea,diarrhoea,muscle pain",596,Malaria "Common symptoms include having trouble with: Reading, spelling or math. Driving. Getting dressed. Telling the difference between objects that are moving and those that are still. Judging how far away objects are. Using everyday objects or tools. Identifying left from right. Other common symptoms include: Anxiety. Confusion. Changes in behavior and personality. Memory problems may occur later in the disease. Causes The most common cause of posterior cortical atrophy is a form of Alzheimer's disease that's not typical. It affects the back of the brain. Other less common causes include corticobasal degeneration, Lewy body dementia and Creutzfeldt-Jakob disease. Researchers are looking at potential gene variations that may be related to the condition. Risk factors Further study is needed to determine whether the risk factors for Alzheimer's disease may play a role in posterior cortical atrophy. By Mayo Clinic Staff By Mayo Clinic Staff Posterior cortical atrophy care at Mayo Clinic",785,Posterior Cortical Atrophy "joint pain,neck pain,knee pain,hip joint pain,swelling joints,painful walking",700,Osteoarthristis "similar to being on a roller coaster: Sometimes temporal lobe seizures impair your ability to respond to others. This type of temporal lobe seizure usually lasts 30 seconds to two minutes. Characteristic signs and symptoms include: Loss of awareness of surroundings Staring Lip smacking Repeated swallowing or chewing Unusual finger movements, such as picking motions After a temporal lobe seizure, you may have: A period of confusion and difficulty speaking Inability to recall what occurred during the seizure Unawareness of having had a seizure Extreme sleepiness In extreme cases, what starts as a temporal lobe seizure evolves into a generalized tonic-clonic (grand mal) seizure — featuring convulsions and loss of consciousness.",971,Temporal Lobe Seizure "vomiting,yellowish skin,abdominal pain,swelling of stomach,distention of abdomen,history of alcohol consumption,fluid overload",33,Alcoholic Hepatitis "vomiting,fatigue,anxiety,sweating,headache,nausea,excessive hunger,drying and tingling lips,slurred speech,irritability,palpitations",504,Hypoglycemia "joint pain,vomiting,yellowish skin,dark urine,nausea,loss of appetite,abdominal pain,diarrhoea,mild fever,yellowing of eyes,muscle pain",464,Hepatitis A "skin rash,chills,joint pain,vomiting,fatigue,high fever,headache,nausea,loss of appetite,pain behind the eyes,back pain,malaise,muscle pain,red spots over body",275,Dengue "itching,vomiting,yellowish skin,nausea,loss of appetite,abdominal pain,yellowing of eyes",207,Chronic Cholestasis "producing some or all of the following signs and symptoms: Headache that gets worse Vomiting Drowsiness and progressive loss of consciousness Dizziness Confusion Unequal pupil size Slurred speech Loss of movement (paralysis) on the opposite side of the body from the head injury As more blood fills your brain or the narrow space between your brain and skull, other signs and symptoms may appear, such as: Lethargy Seizures Unconsciousness",533,Intracranial Hematoma "muscle weakness,stiff neck,swelling joints,movement stiffness,painful walking",72,Arthritis "vomiting,indigestion,loss of appetite,abdominal pain,passage of gases,internal itching",735,Peptic Ulcer Diseae "chills,vomiting,fatigue,weight loss,cough,high fever,breathlessness,sweating,loss of appetite,mild fever,yellowing of eyes,swelled lymph nodes,malaise,phlegm,chest pain,blood in sputum",1019,Tuberculosis "fatigue,cough,high fever,breathlessness,family history,mucoid sputum",149,Bronchial Asthma "itching,skin rash,stomach pain,burning micturition,spotting urination",308,Drug Reaction "vomiting,breathlessness,sweating,chest pain",447,Heart Attack "skin rash,high fever,blister,red sore around nose,yellow crust ooze",515,Impetigo "Signs and symptoms of myofascial pain syndrome may include: Deep, aching pain in a muscle Pain that persists or worsens A tender knot in a muscle Difficulty sleeping due to pain",665,Myofascial Pain Syndrome "skin rash,pus filled pimples,blackheads,scurring",7,Acne "itching,skin rash,fatigue,lethargy,high fever,headache,loss of appetite,mild fever,swelled lymph nodes,malaise,red spots over body",193,Chicken Pox Risk factors: The risk of radiation enteritis is higher in people undergoing radiation treatments for cancers in the belly and the pelvis. Radiation enteritis occurs because radiation therapy can cause irritation of the intestines. By Mayo Clinic Staff By Mayo Clinic Staff Radiation enteritis care at Mayo Clinic,834,Radiation Enteritis "fatigue,mood swings,weight loss,restlessness,sweating,diarrhoea,fast heart rate,excessive hunger,muscle weakness,irritability,abnormal menstruation",502,Hyperthyroidism "vomiting,sunken eyes,dehydration,diarrhoea",402,Gastroenteritis "joint pain,vomiting,fatigue,yellowish skin,dark urine,nausea,loss of appetite,abdominal pain,yellowing of eyes",467,Hepatitis D "continuous sneezing,shivering,chills,watering from eyes",35,Allergy "A hemangioma may be present at birth, but more often appears during the first several months of life. It starts as a flat red mark anywhere on the body, most often on the face, scalp, chest or back. Usually a child has only one mark. Some children may have more than one, particularly if they're part of a multiple birth. During your child's first year, the red mark grows rapidly into a spongy, rubbery-looking bump that sticks out from the skin. The hemangioma then enters a rest phase and, eventually, it begins to slowly disappear. Many hemangiomas disappear by age 5, and most are gone by age 10. The skin may be slightly discolored or raised after the hemangioma goes away.",457,Hemangioma "I've been having a headache, chest pain, dizziness, and trouble concentrating.",500,Hypertension "can cause: Hay fever, Sneezing Itching of the nose, eyes or roof of the mouth Runny, stuffy nose Watery, red or swollen eyes (conjunctivitis) A food allergy can cause: A food allergy Tingling in the mouth Swelling of the lips, tongue, face or throat Hives Anaphylaxis An insect sting allergy can cause: An insect sting allergy A large area of swelling (edema) at the sting site Itching or hives all over the body Cough, chest tightness, wheezing or shortness of breath Anaphylaxis A drug allergy can cause: A drug allergy Hives Itchy skin Rash Facial swelling Wheezing Anaphylaxis Atopic dermatitis, an allergic skin condition also called eczema, can cause skin to: Atopic dermatitis, Itch Redden Flake or peel Anaphylaxis Some types of allergies, including allergies to foods and insect stings, can trigger a severe reaction known as anaphylaxis. A life-threatening medical emergency, anaphylaxis can cause you to go into shock. Signs and symptoms of anaphylaxis include: Loss of consciousness A drop in blood pressure Severe shortness of breath Skin rash Lightheadedness A rapid, weak pulse Nausea and vomiting",34,Allergies "itching,vomiting,fatigue,weight loss,high fever,yellowish skin,dark urine,abdominal pain",541,Jaundice "continuous sneezing,chills,fatigue,cough,high fever,headache,swelled lymph nodes,malaise,phlegm,throat irritation,redness of eyes,sinus pressure,runny nose,congestion,chest pain,loss of smell,muscle pain",234,Common Cold Signs and symptoms of gastroparesis include: Vomiting Nausea Abdominal bloating Abdominal pain A feeling of fullness after eating just a few bites Vomiting undigested food eaten a few hours earlier Acid reflux Changes in blood sugar levels Lack of appetite Weight loss and malnutrition Many people with gastroparesis don't have any noticeable signs and symptoms.,405,Gastroparesis "chills,vomiting,fatigue,high fever,headache,nausea,constipation,abdominal pain,diarrhoea,toxic look (typhos),belly pain",1026,Typhoid "Other peripheral artery disease symptoms may include: Coldness in the lower leg or foot, especially when compared with the other side Leg numbness or weakness No pulse or a weak pulse in the legs or feet Painful cramping in one or both of the hips, thighs or calf muscles after certain activities, such as walking or climbing stairs Shiny skin on the legs Skin color changes on the legs Slower growth of the toenails Sores on the toes, feet or legs that won't heal Pain when using the arms, such as aching and cramping when knitting, writing or doing other manual tasks Erectile dysfunction Hair loss or slower hair growth on the legs If peripheral artery disease gets worse, pain may occur during rest or when lying down. The pain may interrupt sleep. Hanging the legs over the edge of the bed or walking may temporarily relieve the pain.",741,Peripheral Artery Disease "fatigue,yellowish skin,nausea,loss of appetite,yellowing of eyes,family history",466,Hepatitis C "Low sperm count symptoms might include: Problems with sexual function — for example, low sex drive or difficulty maintaining an erection (erectile dysfunction) Pain, swelling or a lump in the testicle area Decreased facial or body hair or other signs of a chromosome or hormone abnormality",588,Low Sperm Count "muscle wasting,patches in throat,high fever,extra marital contacts",27,Aids "MSA: Parkinsonian type This is the most common type of MSA. The signs and symptoms are similar to those of Parkinson's disease, such as: MSA Stiff muscles Difficulty bending your arms and legs Slow movement (bradykinesia) Tremors can occur at rest or when moving your arms or legs Soft voice Problems with posture and balance Cerebellar type The main signs and symptoms are problems with muscle coordination (ataxia), but others may include: Impaired movement and coordination, such as unsteady gait and loss of balance Slurred, slow or low-volume speech (dysarthria) Visual disturbances, such as blurred or double vision and difficulty focusing your eyes Difficulty swallowing (dysphagia) or chewing Changes in speech, such as slurred speech General signs and symptoms In addition, the primary sign of multiple system atrophy is autonomic failure, which may cause problems with body functions you can't control. This may include: Postural (orthostatic) hypotension Postural hypotension is a form of low blood pressure that makes you feel dizzy or lightheaded, or even faint, when you stand up from sitting or lying down. Not everyone with MSA has postural hypotension. MSA You can also develop dangerously high blood pressure levels while lying down (supine hypertension). Urinary and bowel dysfunction Constipation Loss of bladder or bowel control (incontinence) Changes in sweat production Producing less sweat Heat intolerance due to reduced sweating Impaired body temperature control, often causing cold hands or feet Sleep disorders Agitated sleep due to ""acting out"" dreams Abnormal breathing at night or a harsh breathing sound (stridor) Sexual dysfunction Inability to achieve or maintain an erection (impotence) Loss of libido Cardiovascular problems Color changes in hands and feet caused by pooling of blood Psychiatric problems Difficulty controlling emotions, such as laughing or crying inappropriately",654,Multiple System Atrophy "vomiting,headache,nausea,spinning movements,loss of balance,unsteadiness",0,(Vertigo) Paroymsal Positional Vertigo "Other signs and symptoms of a popliteal artery aneurysm include: Knee pain Lower leg pain Swelling behind the knee Pulsing sensation behind the knee Causes An aneurysm is a ballooning in a weak spot in an artery wall. Many different things can cause the popliteal artery wall to become weak, including: Clogged arteries (atherosclerosis) High blood pressure Wear and tear of the popliteal artery due to repetitive use of the knee joint Weakening of the artery wall Risk factors Popliteal artery aneurysms are rare. They are more common in men than in women. Popiteal artery aneurysms often occur in men with abdominal aortic aneurysm (AAA), a swelling of the wall of the body's main artery (aorta). Anyone diagnosed with popliteal artery aneurysm should be screened for AAA. AAA Other risk factors for popliteal artery aneurysm include: Increasing age High blood pressure (hypertension) Smoking Narrowing of a heart valve (stenotic disease) Having three or more aneurysms anywhere in the body Complications Complications of popliteal artery aneurysm include blood clots (thrombosis) and, rarely, rupture of the aneurysm. Thrombosis of a popliteal artery aneurysm can cause a severe lack of blood flow (ischemia) in the lower leg, which may result in loss of the limb. Sudden leg ischemia can cause the following signs and symptoms: A change in skin color in the affected area No pulse behind the knee Skin in the affected area feels cold Numbness in the leg Inability to move the foot The risk of popliteal artery aneurysm rupture is low. Prevention Smoking and high blood pressure (hypertension) increase the risk of blood vessel (vascular) problems that can lead to popliteal artery and other aneurysms. Following a heart-healthy lifestyle — such as not smoking, eating a nutritious diet and getting regular exercise — can help prevent heart disease and blood vessel damage. By Mayo Clinic Staff By Mayo Clinic Staff Popliteal artery aneurysm care at Mayo Clinic",778,Popliteal Artery Aneurysm "vomiting,headache,weakness of one body side,altered sensorium",718,Paralysis (Brain Hemorrhage) "stomach pain,acidity,ulcers on tongue,vomiting,cough,chest pain",412,Gerd "t heal: Tingling, pain or numbness of the lips or the skin around the mouth",577,Lip Cancer "you may have: Increased thirst Frequent urination Blurred vision Tiredness or weakness Headache Nausea and vomiting Shortness of breath Stomach pain Fruity breath odor A very dry mouth Low blood sugar (hypoglycemia) If your blood sugar is too low, you may have: Shakiness Anxiety Tiredness or drowsiness Weakness Sweating Hunger A feeling of tingling on your skin Dizziness or lightheadedness Headache Difficulty speaking Blurry vision Confusion Loss of consciousness Some people, especially those who've had diabetes for a long time, develop a condition known as hypoglycemia unawareness. That means they don't have warning symptoms that signal a drop in blood sugar. If you have any symptoms of high or low blood sugar, test your blood sugar right away. Based on the test results, follow your diabetes treatment. If you don't start to feel better quickly, or you start to feel worse, get medical care right away.",287,Diabetic Coma Signs and symptoms include: Three or more recurrent episodes of vomiting that start around the same time and last for a similar length of time Varying intervals of generally normal health without nausea between episodes Intense nausea and sweating before an episode starts Other signs and symptoms during a vomiting episode may include: Abdominal pain Diarrhea Dizziness Sensitivity to light Headache Retching or gagging,262,Cyclic Vomiting Syndrome "Signs and symptoms of strep throat can include: Throat pain that usually comes on quickly Painful swallowing Red and swollen tonsils, sometimes with white patches or streaks of pus Tiny red spots on the area at the back of the roof of the mouth (soft or hard palate) Swollen, tender lymph nodes in your neck Fever Headache Rash Nausea or vomiting, especially in younger children Body aches It's possible for you or your child to have many of these signs and symptoms but not have strep throat. The cause of these signs and symptoms could be a viral infection or some other illness. That's why your doctor generally tests specifically for strep throat. It's also possible for you to be exposed to a person who carries strep but shows no symptoms.",944,Strep Throat "joint pain,vomiting,fatigue,high fever,yellowish skin,dark urine,nausea,loss of appetite,abdominal pain,yellowing of eyes,acute liver failure,coma,stomach bleeding",468,Hepatitis E "burning micturition,bladder discomfort,foul smell of urine,continuous feel of urine",1035,Urinary Tract Infection "itching,fatigue,lethargy,yellowish skin,dark urine,loss of appetite,yellow urine,yellowing of eyes,malaise,receiving blood transfusion,receiving unsterile injections",465,Hepatitis B "constipation,pain during bowel movements,pain in anal region,bloody stool,irritation in anus",297,Dimorphic Hemmorhoids(Piles) "itching,skin rash,nodal skin eruptions,dischromic patches",394,Fungal Infection "Wheat allergy signs and symptoms include: Swelling, itching or irritation of the mouth or throat Hives, itchy rash or swelling of the skin Nasal congestion Headache Difficulty breathing Cramps, nausea or vomiting Diarrhea Anaphylaxis Anaphylaxis For some people, wheat allergy may cause a life-threatening reaction called anaphylaxis. In addition to other signs and symptoms of wheat allergy, anaphylaxis may cause: Swelling or tightness of the throat Chest pain or tightness Severe difficulty breathing Trouble swallowing Pale, blue skin color Dizziness or fainting",1067,Wheat Allergy "chills,fatigue,cough,high fever,breathlessness,sweating,malaise,phlegm,chest pain,fast heart rate,rusty sputum",766,Pneumonia "headache,chest pain,dizziness,loss of balance,lack of concentration",501,Hypertension "BPH: Frequent or urgent need to pee, also called urination. Peeing more often at night. Trouble starting to pee. Weak urine stream, or a stream that stops and starts. Dribbling at the end of urination. Not being able to fully empty the bladder. Less common symptoms include: Urinary tract infection. Not being able to pee. Blood in the urine. The symptoms of BPH tend to slowly get worse. But sometimes they stay the same or even improve over time. BPH The size of the prostate doesn't always determine how serious the symptoms are. Some people with slightly enlarged prostates can have major symptoms. Others who have very enlarged prostates can have minor problems. And some people with enlarged prostates don't have any symptoms at all. Other possible causes of urinary symptoms Some other health problems can lead to symptoms that are like those caused by enlarged prostate. These include: Urinary tract infection. Inflamed prostate. Narrowing of the urethra, the tube that carries urine out of the body. Scarring in the bladder neck due to past surgery. Bladder or kidney stones. Problems with nerves that control the bladder. Cancer of the prostate or bladder. Some medicines also may lead to symptoms that seem like those caused by BPH. These include: BPH Powerful pain-relieving medicines called opioids. Cold and allergy medicines. Older medicines for depression called tricyclic antidepressants.",108,Benign Prostatic Hyperplasia "Dupuytren contracture gets worse slowly, over years. The condition begins with a firm lump in the palm of the hand. This lump might be a little tender, but usually isn't painful. Over time, the lump can extend into a hard cord under the skin and up into the finger. This cord tightens and pulls the finger toward the palm, sometimes severely. Dupuytren contracture most commonly affects the two fingers farthest from the thumb. The condition often occurs in both hands.",316,Dupuytrens Contracture "Physical defects: Physical defects may include: Distinctive facial features, including small eyes, an exceptionally thin upper lip, a short, upturned nose, and a smooth skin surface between the nose and upper lip Deformities of joints, limbs and fingers Slow physical growth before and after birth Vision difficulties or hearing problems Small head circumference and brain size Heart defects and problems with kidneys and bones Brain and central nervous system problemsProblems with the brain and central nervous system may include: Poor coordination or balance Intellectual disability, learning disorders and delayed development Poor memory Trouble with attention and with processing information Difficulty with reasoning and problem-solving Difficulty identifying consequences of choices Poor judgment skills Jitteriness or hyperactivity Rapidly changing moods Social and behavioral issuesProblems in functioning, coping and interacting with others may include: Difficulty in school Trouble getting along with others Poor social skills Trouble adapting to change or switching from one task to another Problems with behavior and impulse control Poor concept of time Problems staying on task Difficulty planning or working toward a goal When to see a doctorIf you're pregnant and can't stop drinking, ask your obstetrician, primary care doctor or mental health professional for help. Because early diagnosis may help reduce the risk of long-term problems for children with fetal alcohol syndrome, let your child's doctor know if you drank alcohol while you were pregnant. Don't wait for problems to arise before seeking help. If you have adopted a child or are providing foster care, you may not know if the biological mother drank alcohol while pregnant — and it may not initially occur to you that your child may have fetal alcohol syndrome. However, if your child has problems with learning and behavior, talk with his or her doctor so that the underlying cause might be identified. Request an appointment There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. From Mayo Clinic to your inbox Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Click here for an email preview. Email ErrorEmail field is required ErrorInclude a valid email address Learn more about Mayo Clinic’s use of data. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Subscribe! Thank you for subscribing! You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Distinctive facial features, including small eyes, an exceptionally thin upper lip, a short, upturned nose, and a smooth skin surface between the nose and upper lip Deformities of joints, limbs and fingers Slow physical growth before and after birth Vision difficulties or hearing problems Small head circumference and brain size Heart defects and problems with kidneys and bones Brain and central nervous system problemsProblems with the brain and central nervous system may include: Poor coordination or balance Intellectual disability, learning disorders and delayed development Poor memory Trouble with attention and with processing information Difficulty with reasoning and problem-solving Difficulty identifying consequences of choices Poor judgment skills Jitteriness or hyperactivity Rapidly changing moods Social and behavioral issuesProblems in functioning, coping and interacting with others may include: Difficulty in school Trouble getting along with others Poor social skills Trouble adapting to change or switching from one task to another Problems with behavior and impulse control Poor concept of time Problems staying on task Difficulty planning or working toward a goal When to see a doctorIf you're pregnant and can't stop drinking, ask your obstetrician, primary care doctor or mental health professional for help. Distinctive facial features, including small eyes, an exceptionally thin upper lip, a short, upturned nose, and a smooth skin surface between the nose and upper lip Deformities of joints, limbs and fingers Slow physical growth before and after birth Vision difficulties or hearing problems Small head circumference and brain size Heart defects and problems with kidneys and bones Brain and central nervous system problems Problems with the brain and central nervous system may include: Poor coordination or balance Intellectual disability, learning disorders and delayed development Poor memory Trouble with attention and with processing information Difficulty with reasoning and problem-solving Difficulty identifying consequences of choices Poor judgment skills Jitteriness or hyperactivity Rapidly changing moods Social and behavioral issues Problems in functioning, coping and interacting with others may include: Difficulty in school Trouble getting along with others Poor social skills Trouble adapting to change or switching from one task to another Problems with behavior and impulse control Poor concept of time Problems staying on task Difficulty planning or working toward a goal",374,Fetal Alcohol Syndrome "The most common pink eye symptoms include: Redness in one or both eyes. Itchiness in one or both eyes. A gritty feeling in one or both eyes. A discharge in one or both eyes that forms a crust during the night that may prevent your eye or eyes from opening in the morning. Tearing. Sensitivity to light, called photophobia.",756,Pink Eye "back pain,weakness in limbs,neck pain,dizziness,loss of balance",186,Cervical Spondylosis "Cardiogenic shock signs and symptoms include: Rapid breathing Severe shortness of breath Sudden, rapid heartbeat (tachycardia) Loss of consciousness Weak pulse Low blood pressure (hypotension) Sweating Pale skin Cold hands or feet Urinating less than normal or not at all Symptoms of a heart attack Because cardiogenic shock usually occurs in people who are having a severe heart attack, it's important to know the signs and symptoms of a heart attack. These include: Pressure, fullness or a squeezing pain in the center of your chest that lasts for more than a few minutes Pain spreading to your shoulder, one or both of your arms, your back, or even your teeth and jaw Increasing episodes of chest pain Shortness of breath Sweating Lightheadedness or sudden dizziness Nausea and vomiting Seek medical attention quickly when having these signs or symptoms to decrease your risk of developing cardiogenic shock.",171,Cardiogenic Shock "acidity,indigestion,headache,blurred and distorted vision,excessive hunger,stiff neck,depression,irritability,visual disturbances",630,Migraine A tendency to hold reading material farther away to make the letters clearer: Blurred vision at normal reading distance Eyestrain or headaches after reading or doing close-up work You may notice these symptoms are worse if you are tired or are in an area with dim lighting.,801,Presbyopia "fatigue,weight loss,restlessness,lethargy,irregular sugar level,blurred and distorted vision,obesity,excessive hunger,increased appetite,polyuria",285,Diabetes Signs and symptoms that sometimes accompany knee pain include: Swelling and stiffness Redness and warmth to the touch Weakness or instability Popping or crunching noises Inability to fully straighten the knee,561,Knee Pain "fatigue,weight gain,cold hands and feets,mood swings,lethargy,dizziness,puffy face and eyes,enlarged thyroid,brittle nails,swollen extremeties,depression,irritability,abnormal menstruation",511,Hypothyroidism They include: Blue or gray skin due to low oxygen levels. Excessive sleepiness. Poor feeding. Poor growth. Pounding heartbeat. Fast breathing. Shortness of breath.,1018,Truncus Arteriosus Signs and symptoms associated with galactorrhea include: Persistent or intermittent milky nipple discharge Nipple discharge involving multiple milk ducts Spontaneously leaked or manually expressed nipple discharge One or both breasts affected Absent or irregular menstrual periods Headaches or vision problems,395,Galactorrhea "skin rash,joint pain,skin peeling,silver like dusting,small dents in nails,inflammatory nails",822,Psoriasis "Pain from mittelschmerz may be: On one side of your lower abdomen Dull and achy, similar to menstrual cramps Sharp and sudden Accompanied by slight vaginal bleeding or discharge Rarely, severe Mittelschmerz pain occurs on the side of the ovary that's releasing an egg (ovulating). The pain may switch sides every other month, or you may feel pain on the same side for several months. Keep track of your menstrual cycle for several months and note when you feel lower abdominal pain. If it occurs midcycle and goes away without treatment, it's most likely mittelschmerz.",639,Mittelschmerz "including: Blood in your urine, which may appear pink, red or cola colored Pain in your back or side that doesn't go away Loss of appetite Unexplained weight loss Tiredness Fever",552,Kidney Cancer "CMV CMV: Newborns who became infected with CMV before they were born (congenital CMV). Infants who become infected during birth or shortly afterward (perinatal CMV). This group includes babies infected through breast milk. People who have weakened immune systems, such as those who have had an organ, bone marrow or stem cell transplant, or those who are infected with HIV. Babies Most babies who have congenital CMV appear healthy at birth. CMV A few babies who have congenital CMV who appear healthy at birth develop signs over time — sometimes not for months or years after birth. The most common of these late-occurring signs are hearing loss and developmental delay. A small number of babies may also develop vision problems. CMV The following signs and symptoms are more common in babies who have congenital CMV and who are sick at birth: CMV Premature birth Low birth weight Yellow skin and eyes (jaundice) Enlarged and poorly functioning liver Purple skin splotches or a rash or both Abnormally small head (microencephaly) Enlarged spleen Pneumonia Seizures People who have weakened immunity If your immune system is weakened, you might experience serious problems that affect your: Eyes Lungs Liver Esophagus Stomach Intestines Brain Healthy adults Most people who are infected with CMV who are otherwise healthy experience few if any symptoms. When first infected, some adults may have symptoms similar to infectious mononucleosis, including: CMV Fatigue Fever Sore throat Muscle aches",226,Cmv "There are different types of: Gaucher disease, and signs and symptoms of disease vary widely, even within the same type. Type 1 is by far the most common. Siblings, even identical twins, with the disease can have different levels of severity. Some people who have Gaucher disease have only mild or no symptoms. Most people who have Gaucher disease have varying degrees of the following problems: Abdominal complaints. Because the liver and especially the spleen can enlarge dramatically, the abdomen can become painfully distended. Skeletal abnormalities. Gaucher disease can weaken bone, increasing the risk of painful fractures. It can also interfere with the blood supply to your bones, which can cause portions of the bone to die. Blood disorders. A decrease in healthy red blood cells (anemia) can result in severe fatigue. Gaucher disease also affects the cells responsible for clotting, which can cause easy bruising and nosebleeds. More rarely, Gaucher disease affects the brain, which can cause abnormal eye movements, muscle rigidity, swallowing difficulties and seizures. One rare subtype of Gaucher disease begins in infancy and typically results in death by 2 years of age.",406,Gauchers Disease "Signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of your body Feeling less sensitive to pain, heat and cold Loss of bowel or bladder function Difficulty walking, sometimes leading to falls Back pain that's worse at night Loss of sensation or muscle weakness, especially in your arms or legs Muscle weakness , which may be mild or severe, in different parts of your body Back pain is a common early symptom of spinal tumors. Pain may also spread beyond your back to your hips, legs, feet or arms and may worsen over time — even with treatment. Spinal tumors progress at different rates depending on the type of tumor.",931,Spinal Cord Tumor "CF: Cystic fibrosis signs and symptoms vary, depending on the severity of the disease. Even in the same person, symptoms may worsen or improve as time passes. Some people may not experience symptoms until their teenage years or adulthood. People who are not diagnosed until adulthood usually have milder disease and are more likely to have atypical symptoms, such as recurring bouts of an inflamed pancreas (pancreatitis), infertility and recurring pneumonia. People with cystic fibrosis have a higher than normal level of salt in their sweat. Parents often can taste the salt when they kiss their children. Most of the other signs and symptoms of CF affect the respiratory system and digestive system. CF Respiratory signs and symptoms The thick and sticky mucus associated with cystic fibrosis clogs the tubes that carry air in and out of your lungs. This can cause signs and symptoms such as: A persistent cough that produces thick mucus (sputum) Wheezing Exercise intolerance Repeated lung infections Inflamed nasal passages or a stuffy nose Recurrent sinusitis Digestive signs and symptoms The thick mucus can also block tubes that carry digestive enzymes from your pancreas to your small intestine. Without these digestive enzymes, your intestines aren't able to completely absorb the nutrients in the food you eat. The result is often: Foul-smelling, greasy stools Poor weight gain and growth Intestinal blockage, particularly in newborns (meconium ileus) Chronic or severe constipation, which may include frequent straining while trying to pass stool, eventually causing part of the rectum to protrude outside the anus (rectal prolapse)",264,Cystic Fibrosis "Signs and symptoms of brain metastases include: Headache, sometimes with vomiting or nausea Mental changes, such as increasing memory problems Seizures Weakness or numbness on one side of the body",133,Brain Metastases "fatigue,cramps,bruising,obesity,swollen legs,swollen blood vessels,prominent veins on calf",1047,Varicose Veins "Common symptoms of esophagitis include: Difficulty swallowing. Painful swallowing. Swallowed food becoming stuck in the esophagus, also known as food impaction. Chest pain, particularly behind the breastbone, that occurs with eating. Heartburn. Acid regurgitation. In infants and young children, particularly those too young to explain their discomfort or pain, symptoms of esophagitis may include: Feeding difficulties, such as irritability, arching of the back and not wanting to eat. Failure to thrive. Chest or belly pain in older children.",355,Esophagitis "ADHD ADHD: Many adults with ADHD aren't aware they have it — they just know that everyday tasks can be a challenge. Adults with ADHD may find it difficult to focus and prioritize, leading to missed deadlines and forgotten meetings or social plans. The inability to control impulses can range from impatience waiting in line or driving in traffic to mood swings and outbursts of anger. ADHD ADHD Adult ADHD symptoms may include: ADHD Impulsiveness Disorganization and problems prioritizing Poor time management skills Problems focusing on a task Trouble multitasking Excessive activity or restlessness Poor planning Low frustration tolerance Frequent mood swings Problems following through and completing tasks Hot temper Trouble coping with stress What's typical behavior and what's ADHD? Almost everyone has some symptoms similar to ADHD at some point in their lives. If your difficulties are recent or occurred only occasionally in the past, you probably don't have ADHD. ADHD is diagnosed only when symptoms are severe enough to cause ongoing problems in more than one area of your life. These persistent and disruptive symptoms can be traced back to early childhood. ADHD ADHD ADHD Diagnosis of ADHD in adults can be difficult because certain ADHD symptoms are similar to those caused by other conditions, such as anxiety or mood disorders. And many adults with ADHD also have at least one other mental health condition, such as depression or anxiety.",22,Adult Adhd "blotchy skin: Rapid heartbeat Perspiration, mostly on your upper body A chilled feeling as the hot flash lets up Feelings of anxiety The frequency and intensity of hot flashes vary among women. A single episode may last a minute or two — or as long as 5 minutes. Hot flashes may be mild or so intense that they disrupt daily activities. They can happen at any time of day or night. Nighttime hot flashes (night sweats) may wake you from sleep and can cause long-term sleep disruptions. How often hot flashes occur varies among women, but most women who report having hot flashes experience them daily. On average, hot flash symptoms persist for more than seven years. Some women have them for more than 10 years.",488,Hot Flashes "The main sign of placenta previa is bright red vaginal bleeding, usually without pain, after 20 weeks of pregnancy. Sometimes, spotting happens before an event with more blood loss. The bleeding may occur with prelabor contractions of the uterus that cause pain. The bleeding may also be triggered by sex or during a medical exam. For some women, bleeding may not occur until labor. Often there is no clear event that leads to bleeding.",761,Placenta Previa "usually at the base of the toes or on the ball or heel: On brown and Black skin, the growth may be lighter than unaffected skin Hard, thickened skin (callus) over a spot on the skin, where a wart has grown inward Black pinpoints, which are small clotted blood vessels commonly called wart seeds A cluster of growths on the sole of the foot (mosaic warts) A growth that interrupts the normal lines and ridges in the skin of your foot Pain or tenderness when walking or standing",765,Plantar Warts "Interstitial cystitis signs and symptoms include: Pain in your pelvis or between the vagina and anus in women Pain between the scrotum and anus (perineum) in men Chronic pelvic pain A persistent, urgent need to urinate Frequent urination, often of small amounts, throughout the day and night (up to 60 times a day) Pain or discomfort while the bladder fills and relief after urinating Pain during sex Symptoms severity is different for everyone, and some people may experience symptom-free periods. Although signs and symptoms of interstitial cystitis may resemble those of a chronic urinary tract infection, there's usually no infection. However, symptoms may worsen if a person with interstitial cystitis gets a urinary tract infection.",529,Interstitial Cystitis "Signs and symptoms of a stroke or TIA include: Sudden numbness or weakness in the face or limbs, often on only one side of the body Sudden trouble speaking and understanding Sudden trouble seeing in one or both eyes Sudden dizziness or loss of balance Sudden, severe headache with no known cause",173,Carotid Artery Disease "you may notice: Fatigue and weakness Excessive thirst and dry mouth Headaches and muscle aches Nausea, vomiting or stomach pain Poor or decreased sleep Increased sensitivity to light and sound Dizziness or a sense of the room spinning Shakiness Decreased ability to concentrate Mood disturbances, such as depression, anxiety and irritability Rapid heartbeat",440,Hangovers "Symptoms of periodontitis can include: Swollen or puffy gums. Bright red, dark red or dark purple gums. Gums that feel tender when touched. Gums that bleed easily. A toothbrush that looks pink after brushing your teeth. Spitting out blood when brushing or flossing your teeth. Bad breath that won't go away. Pus between your teeth and gums. Loose teeth or loss of teeth. Painful chewing. New spaces that develop between your teeth that look like black triangles. Gums that pull away from your teeth, making your teeth look longer than usual, called receding gums. A change in the way your teeth fit together when you bite. When to see a dentist Follow your dentist's recommended schedule for regular checkups. If you notice any symptoms of periodontitis, make an appointment with your dentist as soon as possible. The sooner you get care, the better your chances of reversing damage from periodontitis.",740,Periodontitis A congested or runny nose: Nasal discharge that may be clear at first but might thicken and turn yellow or green Other signs and symptoms of a common cold in a baby may include: Fever Sneezing Coughing Decreased appetite Irritability Difficulty sleeping Trouble nursing or taking a bottle due to nasal congestion,235,Common Cold In Babies "They may include: Breast tenderness or warmth to the touch Breast swelling Thickening of breast tissue, or a breast lump Pain or a burning sensation continuously or while breast-feeding Skin redness, often in a wedge-shaped pattern Generally feeling ill Fever of 101 F (38.3 C) or greater",604,Mastitis "Frozen shoulder typically develops slowly in three stages. Freezing stage. Any movement of the shoulder causes pain, and the shoulder's ability to move becomes limited. This stage lasts from 2 to 9 months. Frozen stage. Pain might lessen during this stage. However, the shoulder becomes stiffer. Using it becomes more difficult. This stage lasts from 4 to 12 months. Thawing stage. The shoulder's ability to move begins to improve. This stage lasts from 5 to 24 months. For some people, the pain worsens at night, sometimes disrupting sleep.",391,Frozen Shoulder "Signs and symptoms of: Ewing sarcoma include: Pain, swelling or tenderness near the affected area Bone pain Unexplained tiredness Fever with no known cause Losing weight without trying",358,Ewing Sarcoma "Kidney stones: Kidney stones form in your kidneys. As stones move into your ureters the thin tubes that allow urine to pass from your kidneys to your bladder signs and symptoms can result. Signs and symptoms of kidney stones can include severe pain, nausea, vomiting, fever, chills and blood in your urine. A kidney stone usually will not cause symptoms until it moves around within the kidney or passes into one of the ureters. The ureters are the tubes that connect the kidneys and bladder. If a kidney stone becomes lodged in the ureters, it may block the flow of urine and cause the kidney to swell and the ureter to spasm, which can be very painful. At that point, you may experience these symptoms: Severe, sharp pain in the side and back, below the ribs Pain that radiates to the lower abdomen and groin Pain that comes in waves and fluctuates in intensity Pain or burning sensation while urinating Other signs and symptoms may include: Pink, red or brown urine Cloudy or foul-smelling urine A persistent need to urinate, urinating more often than usual or urinating in small amounts Nausea and vomiting Fever and chills if an infection is present Pain caused by a kidney stone may change — for instance, shifting to a different location or increasing in intensity — as the stone moves through your urinary tract.",556,Kidney Stones "Areas commonly affected by: Behcet's disease include: Mouth. Painful mouth sores that look similar to canker sores are the most common sign of Behcet's disease. They begin as raised, round lesions in the mouth that quickly turn into painful ulcers. The sores usually heal in one to three weeks, though they do recur. Skin. Some people develop acnelike sores on their bodies. Others develop red, raised and tender nodules on their skin, especially on the lower legs. Genitals. Red, open sores can occur on the scrotum or the vulva. The sores are usually painful and can leave scars. Eyes. Inflammation in the eye (uveitis) causes redness, pain and blurred vision, typically in both eyes. In people with Behcet's disease, the condition can come and go. Joints. Joint swelling and pain often affect the knees in people with Behcet's disease. The ankles, elbows or wrists also might be involved. Signs and symptoms can last one to three weeks and go away on their own. Blood vessels. Inflammation in veins and arteries can cause redness, pain, and swelling in the arms or legs when a blood clot results. Inflammation in the large arteries can lead to complications, such as aneurysms and narrowing or blockage of the vessel. Digestive system. A variety of signs and symptoms can affect the digestive system, including abdominal pain, diarrhea and bleeding. Brain. Inflammation in the brain and nervous system can cause headache, fever, disorientation, poor balance or stroke.",106,Behcets Disease "Symptoms of functional dyspepsia may include: Pain or burning in the stomach, bloating, excessive belching, or nausea after eating An early feeling of fullness when eating. The feeling of fullness also is called satiety. Stomach pain that occurs unrelated to meals or goes away when eating.",393,Functional Dyspepsia The main symptoms of a pneumothorax are sudden chest pain and shortness of breath. Severity of symptoms may depend on how much of the lung is collapsed.,768,Pneumothorax You may experience: The feeling that something is in your eye Eye redness Eye irritation or pain Sensitivity to light and wind Watery eyes (excessive tearing) Mucous discharge and eyelid crusting,345,Entropion "Signs and symptoms of hypothermia include: Shivering Slurred speech or mumbling Slow, shallow breathing Weak pulse Clumsiness or lack of coordination Drowsiness or very low energy Confusion or memory loss Loss of consciousness Bright red, cold skin (in infants) Someone with hypothermia usually isn't aware of his or her condition because the symptoms often begin gradually. Also, the confused thinking associated with hypothermia prevents self-awareness. The confused thinking can also lead to risk-taking behavior.",510,Hypothermia "they may include: Fatigue. Easily bleeding or bruising. Loss of appetite. Nausea. Swelling in the legs, feet or ankles, called edema. Weight loss. Itchy skin. Yellow discoloration in the skin and eyes, called jaundice. Fluid accumulation in the abdomen, called ascites (uh-SAHY-teez). Spiderlike blood vessels on the skin. Redness in the palms of the hands. Pale fingernails, especially the thumb and index finger. Clubbing of the fingers, in which the fingertips spread out and become rounder than usual. For women, absence of or loss of periods not related to menopause. For men, loss of sex drive, testicular shrinkage or breast enlargement, known as gynecomastia. Confusion, drowsiness or slurred speech.",221,Cirrhosis A lump in your neck caused by a swollen lymph node: Blood in your saliva Bloody discharge from your nose Nasal congestion or ringing in your ears Hearing loss Frequent ear infections Sore throat Headaches,671,Nasopharyngeal Carcinoma "CGD: It's also common for people with CGD to experience infections of the skin, liver, stomach and intestines, brain, and eyes. Signs and symptoms associated with infections include: CGD Fever Chest pain when inhaling or exhaling Swollen and sore lymph glands A persistent runny nose Skin irritation that may include a rash, swelling or redness Swelling and redness in your mouth Gastrointestinal problems that may include vomiting, diarrhea, stomach pain, bloody stool or a painful pocket of pus near the anus",212,Chronic Granulomatous Disease "Signs and symptoms of absence seizures include: Sudden stop in motion without falling Lip smacking Eyelid flutters Chewing motions Finger rubbing Small movements of both hands Afterward, there's no memory of the incident. Some people have many episodes daily, which interfere with school or daily activities. A child may have absence seizures for some time before an adult notices the seizures, because they're so brief. A decline in a child's learning ability may be the first sign of this disorder. Teachers may comment about a child's inability to pay attention or that a child is often daydreaming. When to see a doctor Contact your doctor: The first time you notice a seizure If this is a new type of seizure If the seizures continue to occur despite taking anti-seizure medication Contact 911 or emergency services in your area: If you observe prolonged automatic behaviors lasting minutes to hours — activities such as eating or moving without awareness — or prolonged confusion, possible symptoms of a condition called absence status epilepticus After any seizure lasting more than five minutes",750,Petit Mal Seizure "A pilonidal cyst may not cause symptoms. But if it's infected, the skin around the cyst may be swollen and painful. Symptoms of an infected pilonidal cyst include: A pit near the top of the buttocks crease. Pain. Inflamed, swollen skin. Pus or blood leaking from an opening in the skin. An odor from draining pus.",754,Pilonidal Cyst "A noticeable lump or swelling: Pain, if a tumor presses on nerves or muscles",922,Soft Tissue Sarcoma "Male reproductive system: The male reproductive system makes, stores and moves sperm. Testicles produce sperm. Fluid from the seminal vesicles and prostate gland combine with sperm to make semen. The penis ejaculates semen during sexual intercourse. Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. Fetal development If the body doesn't produce enough testosterone during fetal development, the result may be impaired growth of the external sex organs. Depending on when hypogonadism develops and how much testosterone is present, a child who is genetically male may be born with: Female genitals Genitals that are neither clearly male nor clearly female (ambiguous genitals) Underdeveloped male genitals Puberty Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass Voice deepening Growth of body and facial hair Growth of the penis and testicles And it can cause: Excessive growth of the arms and legs in relation to the trunk of the body Development of breast tissue (gynecomastia) Adulthood In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive Decreased energy Depression Over time, men with hypogonadism can develop: Erectile dysfunction Infertility Decrease in hair growth on the face and body Decrease in muscle mass Development of breast tissue (gynecomastia) Loss of bone mass (osteoporosis) Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating Hot flashes When to seek help See your health care provider if you have symptoms of male hypogonadism. Finding the cause of hypogonadism is an important first step to getting appropriate treatment.",598,Male Hypogonadism "Signs and symptoms of: Wilms' tumor vary widely, and some children don't show any obvious signs. But most children with Wilms' tumor experience one or more of these signs and symptoms: An abdominal mass you can feel Abdominal swelling Abdominal pain Other signs and symptoms may include: Fever Blood in the urine Nausea or vomiting or both Constipation Loss of appetite Shortness of breath High blood pressure",1071,Wilms Tumor "may cause signs and symptoms such as: Neuroblastoma in the abdomen Abdominal pain A mass under the skin that isn't tender when touched Changes in bowel habits, such as diarrhea or constipation Neuroblastoma in the chest may cause signs and symptoms such as: Neuroblastoma in the chest Wheezing Chest pain Changes to the eyes, including drooping eyelids and unequal pupil size Other signs and symptoms that may indicate neuroblastoma include: Lumps of tissue under the skin Eyeballs that seem to protrude from the sockets (proptosis) Dark circles, similar to bruises, around the eyes Back pain Fever Unexplained weight loss Bone pain",676,Neuroblastoma "they may include: Pain in the upper right abdomen Feeling full after eating only a small amount of food (early satiety) Nausea Vomiting However, these symptoms are nonspecific and in most instances are due to something else even if you have a liver hemangioma, as these tend to be asymptomatic.",582,Liver Hemangioma "Arteriovenous fistula signs and symptoms may include: Purplish, bulging veins seen through the skin, similar to varicose veins Swelling in the arms or legs Decreased blood pressure Fatigue Heart failure A significant arteriovenous fistula in the lungs (pulmonary arteriovenous fistula) is a serious condition and can cause: Pale gray or blue lips or fingernails due to lack of blood flow (cyanosis) Fingertips to spread out and become rounder than normal (clubbing) Coughing up blood An arteriovenous fistula in the digestive tract can cause gastrointestinal (GI) bleeding.",70,Arteriovenous Fistula "Blood in the urine can look pink, red or cola-colored. Red blood cells cause the urine to change color. It takes only a small amount of blood to turn urine red. The bleeding often isn't painful. But if blood clots get passed in the urine, that can hurt.",119,Blood In Urine "The signs and symptoms of polymyalgia rheumatica usually occur on both sides of the body and might include: Aches or pain in your shoulders Aches or pain in your neck, upper arms, buttocks, hips or thighs Stiffness in affected areas, particularly in the morning or after being inactive for a time Limited range of motion in affected areas Pain or stiffness in your wrists, elbows or knees You might also have more-general signs and symptoms, including: Mild fever Fatigue A general feeling of not being well (malaise) Loss of appetite Unintended weight loss Depression",775,Polymyalgia Rheumatica "Signs and symptoms of appendicitis may include: Sudden pain that begins on the right side of the lower abdomen Sudden pain that begins around your navel and often shifts to your lower right abdomen Pain that worsens if you cough, walk or make other jarring movements Nausea and vomiting Loss of appetite Low-grade fever that may worsen as the illness progresses Constipation or diarrhea Abdominal bloating Flatulence The site of your pain may vary, depending on your age and the position of your appendix. When you're pregnant, the pain may seem to come from your upper abdomen because your appendix is higher during pregnancy.",68,Appendicitis "Lead poisoning symptoms in children: Signs and symptoms of lead poisoning in children include: Developmental delay Learning difficulties Irritability Loss of appetite Weight loss Sluggishness and fatigue Abdominal pain Vomiting Constipation Hearing loss Seizures Eating things, such as paint chips, that aren't food (pica) Lead poisoning symptoms in newborns Babies exposed to lead before birth might: Be born prematurely Have lower birth weight Have slowed growth Lead poisoning symptoms in adults Although children are primarily at risk, lead poisoning is also dangerous for adults. Signs and symptoms in adults might include: High blood pressure Joint and muscle pain Difficulties with memory or concentration Headache Abdominal pain Mood disorders Reduced sperm count and abnormal sperm Miscarriage, stillbirth or premature birth in pregnant women",567,Lead Poisoning Signs and symptoms of intestinal obstruction include: Crampy abdominal pain that comes and goes Loss of appetite Constipation Vomiting Inability to have a bowel movement or pass gas Swelling of the abdomen,532,Intestinal Obstruction "Other less common signs and symptoms of cholestasis of pregnancy may include: Yellowing of the skin and whites of the eyes, called jaundice Nausea Loss of appetite Oily, foul-smelling stools",205,Cholestasis Of Pregnancy Hammertoe and mallet toe feature an abnormal bend in the joints of one or more of your toes. Moving the affected toe may be difficult or painful. Corns and calluses can result from the toe rubbing against the inside of your shoes.,437,Hammertoe And Mallet Toe "signs and symptoms of inflammatory breast cancer include: Rapid change in the appearance of one breast, over the course of several weeks Thickness, heaviness or visible enlargement of one breast Discoloration, giving the breast a red, purple, pink or bruised appearance Unusual warmth of the affected breast Dimpling or ridges on the skin of the affected breast, similar to an orange peel Tenderness, pain or aching Enlarged lymph nodes under the arm, above the collarbone or below the collarbone Flattening or turning inward of the nipple For inflammatory breast cancer to be diagnosed, these symptoms must have been present for less than six months.",523,Inflammatory Breast Cancer whereas others experience signs and symptoms that may include: Fatigue Abdominal discomfort Yellowing of the skin and whites of the eyes (jaundice) An enlarged liver Abnormal blood vessels on the skin (spider angiomas) Skin rashes Joint pains Loss of menstrual periods,88,Autoimmune Hepatitis "Clinical trials: Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. Explore Mayo Clinic studies By Mayo Clinic Staff By Mayo Clinic Staff Sleep disorders care at Mayo Clinic",912,Sleep Disorders "Pityriasis rosea typically begins with an oval, slightly raised, scaly patch — called the herald patch — on the face, back, chest or abdomen. Before the herald patch appears, some people have headache, fatigue, fever or sore throat. A few days to a few weeks after the herald patch appears, you may notice smaller bumps or scaly spots across your face, back, chest or abdomen that look like a pine-tree pattern. The rash can cause itching.",759,Pityriasis Rosea "Prodrome: One or two days before a migraine, you might notice subtle changes that warn of an upcoming migraine, including: Constipation Mood changes, from depression to euphoria Food cravings Neck stiffness Increased urination Fluid retention Frequent yawning Aura For some people, an aura might occur before or during migraines. Auras are reversible symptoms of the nervous system. They're usually visual but can also include other disturbances. Each symptom usually begins gradually, builds up over several minutes and can last up to 60 minutes. Examples of migraine auras include: Visual phenomena, such as seeing various shapes, bright spots or flashes of light Vision loss Pins and needles sensations in an arm or leg Weakness or numbness in the face or one side of the body Difficulty speaking Attack A migraine usually lasts from 4 to 72 hours if untreated. How often migraines occur varies from person to person. Migraines might occur rarely or strike several times a month. During a migraine, you might have: Pain usually on one side of your head, but often on both sides Pain that throbs or pulses Sensitivity to light, sound, and sometimes smell and touch Nausea and vomiting Post-drome After a migraine attack, you might feel drained, confused and washed out for up to a day. Some people report feeling elated. Sudden head movement might bring on the pain again briefly.",631,Migraine Headache "Hyponatremia signs and symptoms may include: Nausea and vomiting Headache Confusion Loss of energy, drowsiness and fatigue Restlessness and irritability Muscle weakness, spasms or cramps Seizures Coma",505,Hyponatremia "Common warts usually occur on your fingers or hands and may be: Small, fleshy, grainy bumps Rough to the touch Sprinkled with black pinpoints, which are small, clotted blood vessels",237,Common Warts "Some signs of being born too early include: Small size, with a head that's large compared with the body. Features that are sharper and less rounded than a full-term baby's features due to a lack of cells that store fat. Fine hair that covers much of the body. Low body temperature, mainly right after birth in the delivery room. Trouble breathing. Feeding problems. The following tables show the median birth weight, length and head circumference of premature babies at different gestational ages for each sex. Weight, length and head circumference by gestational age for boys Gestational age Weight Length Head circumference 40 weeks 7 lbs., 15 oz. (3.6 kg) 20 in. (51 cm) 13.8 in. (35 cm) 35 weeks 5 lbs., 8 oz. (2.5 kg) 18.1 in. (46 cm) 12.6 in. (32 cm) 32 weeks 3 lbs., 15.5 oz. (1.8 kg) 16.5 in. (42 cm) 11.6 in. (29.5 cm) 28 weeks 2 lbs., 6.8 oz. (1.1 kg) 14.4 in. (36.5 cm) 10.2 in. (26 cm) 24 weeks 1 lb., 6.9 oz. (0.65 kg) 12.2 in. (31 cm) 8.7 in. (22 cm) Weight, length and head circumference by gestational age for boys Weight, length and head circumference by gestational age for boys Weight, length and head circumference by gestational age for boys Gestational age Weight Length Head circumference 40 weeks 7 lbs., 15 oz. (22 cm) Gestational age Weight Length Head circumference Gestational age Weight Length Head circumference 40 weeks 7 lbs., 15 oz. (35 cm) 40 weeks 7 lbs., 15 oz. (32 cm) 35 weeks 5 lbs., 8 oz. (29.5 cm) 32 weeks 3 lbs., 15.5 oz. (26 cm) 28 weeks 2 lbs., 6.8 oz. (22 cm) 24 weeks 1 lb., 6.9 oz. (22 cm) Weight, length and head circumference by gestational age for girls Gestational age Weight Length Head circumference 40 weeks 7 lbs., 7.9 oz. (3.4 kg) 20 in. (35 cm) 35 weeks 5 lbs., 4.7 oz. (2.4 kg) 17.7 in. (45 cm) 12.4 in. (31.5 cm) 32 weeks 3 lbs., 12 oz. (1.7 kg) 16.5 in. (42 cm) 11.4 in. (29 cm) 28 weeks 2 lbs., 3.3 oz. (1.0 kg) 14.1 in. (36 cm) 9.8 in. (25 cm) 24 weeks 1 lb., 5.2 oz. (0.60 kg) 12.6 in. (32 cm) 8.3 in. (21 cm) Weight, length and head circumference by gestational age for girls Weight, length and head circumference by gestational age for girls Weight, length and head circumference by gestational age for girls Gestational age Weight Length Head circumference 40 weeks 7 lbs., 7.9 oz. (21 cm) Gestational age Weight Length Head circumference Gestational age Weight Length Head circumference 40 weeks 7 lbs., 7.9 oz. (35 cm) 40 weeks 7 lbs., 7.9 oz. (31.5 cm) 35 weeks 5 lbs., 4.7 oz. (29 cm) 32 weeks 3 lbs., 12 oz. (25 cm) 28 weeks 2 lbs., 3.3 oz. (21 cm) 24 weeks 1 lb., 5.2 oz. (21 cm) Special care If you give birth to a preterm baby, your baby will likely need to stay in a special nursery unit at the hospital. Some infants need to spend time in a unit that cares for them and closely tracks their health day and night. This is called a neonatal intensive care unit (NICU). A step down from the NICU is an intermediate care nursery, which provides less intensive care. Special nursery units are staffed with health care providers and a team that's trained to help preterm babies. NICU Your baby may need extra help feeding and adapting right after delivery. Your health care team can help you understand what's needed and what your baby's care plan will be. Feel free to ask them questions.",796,Premature Birth "Signs and symptoms might include: An unusual lump Sudden pain A dull aching pain or feeling of heaviness in the scrotum Pain that radiates throughout the groin, abdomen or lower back Tender, swollen or hardened testicle Tender, swollen or hardened epididymis (ep-ih-DID-uh-miss), the soft, comma-shaped tube above and behind the testicle that stores and transports sperm Swelling in the scrotum Redness of the skin of the scrotum Nausea or vomiting If the cause of a scrotal mass is an infection, signs and symptoms also might include: Fever Urinary frequency Pus or blood in the urine When to see a doctor Seek emergency medical care if you develop sudden pain in your scrotum. Some conditions require prompt treatment to avoid permanent damage to a testicle. See your doctor if you detect a lump in your scrotum, even if it's not painful or tender, or if you experience other symptoms of a scrotal mass. Some scrotal masses are more common in children. See your doctor if your child experiences symptoms of a scrotal mass, if you have any concerns about the development of the genitals or if a testicle is missing an undescended or retractile testicle, which might increase the risk of some scrotal masses later in life.",889,Scrotal Masses "Frequent throat clearing and sore throat: Hoarseness Wheezing and shortness of breath Heartburn or a sour taste in your mouth In rare cases, coughing up blood",208,Chronic Cough "The signs and symptoms of: Marfan syndrome can vary greatly, even among members of the same family, because the disorder can affect so many different areas of the body. Some people experience only mild effects, but others develop life-threatening complications. Marfan syndrome features may include: Tall and slender build Disproportionately long arms, legs and fingers A breastbone that protrudes outward or dips inward A high, arched palate and crowded teeth Heart murmurs Extreme nearsightedness An abnormally curved spine Flat feet",603,Marfan Syndrome "and may include: Pain or tenderness Redness or bruising Limited motion Muscle spasms Swelling Muscle weakness When to see the doctor Mild strains can be treated at home. See a doctor if your symptoms worsen despite treatment — especially if your pain becomes intolerable, or you experience numbness or tingling. Causes Acute strains can be caused by one event, such as using poor body mechanics to lift something heavy. Chronic muscle strains can result from repetitive injuries when you stress a muscle by doing the same motion over and over. Risk factors Participating in contact sports — such as soccer, football, hockey, boxing and wrestling — can increase your risk of muscle strains. Certain parts of the body are more susceptible to strains during participation in certain sports. Examples include: Legs and ankles. Sports that feature quick starts and jumping, such as hurdling and basketball, can be particularly tough on the Achilles tendon in your ankle. Hands. Gripping sports, such as gymnastics or golf, can increase your risk of muscle strains in your hands. Elbows. Elbow strains are often caused by throwing sports and racquet sports. Prevention Regular stretching and strengthening exercises for your sport, fitness or work activity, as part of an overall physical conditioning program, can help to minimize your risk of muscle strains. Try to be in shape to play your sport; don't play your sport to get in shape. If you have a physically demanding occupation, regular conditioning can help prevent injuries. By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment Oct. 11, 2022 Print Print Share on: FacebookTwitter Facebook Twitter Show references Sprains and strains. National Institute of Arthritis and Musculoskeletal and Skin Diseases. https://www.niams.nih.gov/health-topics/sprains-and-strains/advanced. Accessed April 27, 2018. Walls RM, et al., eds. General principles of orthopedic injuries. In: Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Safran MR, et al. Strain. In: Instructions for Sports Medicine Patients. 2nd ed. Philadelphia, Pa.: Elsevier Saunders; 2012. Sprains, strains and other soft-tissue injuries. American Academy of Orthopaedic Surgeons. https://orthoinfo.aaos.org/en/diseases--conditions/sprains-strains-and-other-soft-tissue-injuries. Show references Sprains and strains. Sprains and strains. Related Associated Procedures Ultrasound Products & Services Book: Mayo Clinic Book of Home Remedies Related Associated Procedures Ultrasound Associated Procedures Ultrasound",657,Muscle Strains "Signs and symptoms of hair loss may include: Gradual thinning on top of head. This is the most common type of hair loss, affecting people as they age. In men, hair often begins to recede at the hairline on the forehead. Women typically have a broadening of the part in their hair. An increasingly common hair loss pattern in older women is a receding hairline (frontal fibrosing alopecia). Circular or patchy bald spots. Some people lose hair in circular or patchy bald spots on the scalp, beard or eyebrows. Your skin may become itchy or painful before the hair falls out. Sudden loosening of hair. A physical or emotional shock can cause hair to loosen. Handfuls of hair may come out when combing or washing your hair or even after gentle tugging. This type of hair loss usually causes overall hair thinning but is temporary. Full-body hair loss. Some conditions and medical treatments, such as chemotherapy for cancer, can result in the loss of hair all over your body. The hair usually grows back. Patches of scaling that spread over the scalp. This is a sign of ringworm. It may be accompanied by broken hair, redness, swelling and, at times, oozing.",435,Hair Loss "Symptoms of pseudomembranous colitis may include: Watery diarrhea. Stomach cramps, pain or tenderness. Fever. Pus or mucus in the stool. Nausea. Dehydration. Symptoms of pseudomembranous colitis can begin as soon as 1 to 2 days after you start taking an antibiotic, or as long as several months or longer after you finish taking the antibiotic.",820,Pseudomembranous Colitis "Many people with von: Willebrand disease don't know it because the signs are mild or absent. The most common sign of the condition is abnormal bleeding. There are three main types of the disease. The amount of bleeding varies from one person to another, depending on the type and severity of the disease. If you have von Willebrand disease, you might have: Excessive bleeding from an injury or after surgery or dental work Frequent nosebleeds that don't stop within 10 minutes Heavy or long menstrual bleeding Heavy bleeding during labor and delivery Blood in your urine or stool Easy bruising or lumpy bruises Menstrual signs and symptoms might include: Blood clots greater than 1 inch (2.5 centimeters) in diameter in your menstrual flow The need to change your menstrual pad or tampon more than once an hour The need to use double sanitary protection for menstrual flow Symptoms of anemia, including tiredness, fatigue or shortness of breath",1062,Von Willebrand Disease "The chest pain or discomfort may feel like: Burning Fullness Pressure Squeezing Pain may also be felt in the arms, neck, jaw, shoulder or back. Other symptoms of angina include: Dizziness Fatigue Nausea Shortness of breath Sweating The severity, duration and type of angina can vary. New or different symptoms may signal a more dangerous form of angina (unstable angina) or a heart attack. Any new or worsening angina symptoms need to be evaluated immediately by a health care provider who can determine whether you have stable or unstable angina. Angina in women Symptoms of angina in women can be different from the classic angina symptoms. These differences may lead to delays in seeking treatment. For example, chest pain is a common symptom in women with angina, but it may not be the only symptom or the most prevalent symptom for women. Women may also have symptoms such as: Discomfort in the neck, jaw, teeth or back Nausea Shortness of breath Stabbing pain instead of chest pressure Stomach (abdominal) pain",52,Angina "When to see a doctor: Contact your doctor if your child has persistent pain in an injured limb. Seek immediate medical attention if a child is unable to bear weight or if there is obvious pain, deformity and swelling. Causes Childhood fractures most commonly occur with a fall. Arm fractures are more common than leg fractures, since the common reaction is to throw out your arms to catch yourself when you fall. Risk factors The risk of greenstick fractures is higher in young children because their bones are softer and more flexible than adult bones. In a greenstick fracture, the bone bends and cracks instead of breaking into separate pieces. Most greenstick fractures occur in children under age 10. By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment Feb. 25, 2021 Print Print Share on: FacebookTwitter Facebook Twitter Show references Marx JA, et al., eds. General principles of orthopedic injuries. In: Rosen's Emergency Medicine: Concepts and Clinical Practice. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed March 21, 2016. Kliegman RM, et al. Common fractures. In: Nelson Textbook of Pediatrics. 20th ed. Philadelphia, Pa.: Elsevier; 2016. Schweich P. Distal forearm fractures in children: Diagnosis and assessment. http://www.uptodate.com/home. Mencio GA. Fractures and dislocations of the forearm, wrist and hand. In: Green's Skeletal Trauma in Children. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2015. Mathison DJ, et al. General principles of fracture management: Fracture patterns and description in children. March 21, 2016. Distal forearm fractures in children: Initial management. Closed reduction and casting of distal forearm fractures in children. Herring JA. Upper extremity injuries. In: Tachdjian's Pediatric Orthopedics. Show references Marx JA, et al., eds. Marx JA, et al., eds. Related Greenstick fracture Associated Procedures CT scan Ultrasound X-ray Products & Services Book: Mayo Clinic Guide to Raising a Healthy Child Related Greenstick fracture Greenstick fracture",429,Greenstick Fractures "Signs and symptoms of trachoma usually affect both eyes and may include: Mild itching and irritation of the eyes and eyelids Eye discharge containing mucus or pus Eyelid swelling Light sensitivity (photophobia) Eye pain Eye redness Vision loss Young children are particularly susceptible to infection. But the disease progresses slowly, and the more painful symptoms may not emerge until adulthood. The World Health Organization (WHO) has identified five stages in the development of trachoma: Inflammation — follicular. The early infection has five or more follicles — small bumps that contain lymphocytes, a type of white blood cell — visible with magnification on the inner surface of your upper eyelid (conjunctiva). Inflammation — intense. In this stage, your eye is now highly infectious and becomes irritated, with a thickening or swelling of the upper eyelid. Eyelid scarring. Repeated infections lead to scarring of the inner eyelid. The scars often appear as white lines when examined with magnification. Your eyelid may become distorted and may turn in (entropion). In-turned eyelashes (trichiasis). The scarred inner lining of your eyelid continues to deform, causing your lashes to turn in so that they rub on and scratch the transparent outer surface of your eye (cornea). Corneal clouding (opacity). The cornea becomes affected by an inflammation that is most commonly seen under your upper lid. Continuous inflammation compounded by scratching from the in-turned lashes leads to clouding of the cornea. All the signs of trachoma are more severe in your upper lid than in your lower lid. Without intervention, a disease process that begins in childhood can continue to advance into adulthood.",1003,Trachoma "and may include: Difficulty walking Difficulty maintaining balance Loss of muscle coordination Loss of muscle tone or weakness Loss of fine motor skills, such as picking up objects Difficulty swallowing Slurred speech or stuttering Memory loss and other thinking (cognitive) impairment Vision problems Sleep disturbances Seizures Hallucinations Unusual involuntary movements Types of paraneoplastic syndromes Examples of paraneoplastic syndromes of the nervous system include: Cerebellar degeneration (cerebellar ataxia). This is the loss of nerve cells in the area of the brain that controls muscle functions and balance (cerebellum). Signs and symptoms may include unsteady or impaired walking, lack of muscle coordination in your limbs, inability to maintain your trunk posture, dizziness, nausea, involuntary eye movement, double vision, difficulty speaking, or difficulty swallowing. Limbic encephalitis. This is inflammation affecting a region of the brain known as the limbic system, which controls emotions, behaviors and certain memory functions. People with this disorder may experience personality changes or mood disturbances, memory loss, seizures, hallucinations, or drowsiness. Encephalomyelitis. This syndrome refers to inflammation of the brain and spinal cord. There may be a wide variety of symptoms and signs depending on the area affected. Opsoclonus-myoclonus. This syndrome is due to dysfunction of the cerebellum or its connections. It can cause rapid, irregular eye movements (opsoclonus) and involuntary, chaotic muscle jerks (myoclonus) in your limbs and trunk. Stiff person syndrome. Previously called stiff man syndrome, this syndrome is characterized by progressive, severe muscle stiffness or rigidity, mainly affecting your spine and legs. It may also cause painful muscle spasms. Myelopathy. This term refers to a syndrome of injury limited to the spinal cord. Depending on the level of spinal cord injury, you may have changes in bowel and bladder function, and severe weakness and numbness up to a certain level in your body. If the level of injury includes your neck, you can have severe disability affecting all four limbs. Lambert-Eaton myasthenic syndrome. This is a syndrome caused by disrupted communication between nerves and muscles. Signs and symptoms include pelvic and lower extremity muscle weakness, fatigue, difficulty swallowing, difficulty speaking, irregular eye movement, and double vision. Autonomic nervous system problems can include dry mouth and erectile dysfunction in males. When it occurs as a paraneoplastic syndrome, Lambert-Eaton myasthenic syndrome is typically associated with lung cancer. Myasthenia gravis. Myasthenia gravis is also related to disrupted communication between nerves and muscles and also characterized by weakness and rapid fatigue of any of the muscles that are under voluntary control, including muscles in your face, eyes, arms and legs. The muscles involved in chewing, swallowing, talking and breathing may be affected as well. When myasthenia gravis occurs as a paraneoplastic syndrome, it is typically associated with cancer of the thymus gland (thymoma). Neuromyotonia. Neuromyotonia — also known as Isaacs' syndrome — is characterized by abnormal impulses in nerve cells outside the brain and spinal cord (peripheral nerve hyperexcitability) that control muscle movement. These impulses can cause twitching, muscle rippling that looks like a ""bag of worms,"" progressive stiffness, muscle cramps, slowed movement and other muscle impairments. Peripheral neuropathy. This condition refers to patterns of damage to nerves that transmit messages from the brain or spinal column to the rest of your body. When damage involves only the sensory nerves of the peripheral nervous system, you can have pain and disturbances in sensation anywhere in your body. Dysautonomia. Dysautonomia refers to a wide range of signs and symptoms resulting from injury to the nerves that regulate involuntary body functions (autonomic nervous system), such as heart rate, blood pressure, sweating, and bowel and bladder functions. When this part of the nervous system is affected, common symptoms are low blood pressure, irregular heartbeats and trouble breathing.",719,Paraneoplastic Syndromes "signs and symptoms might include: Nausea Vomiting Loss of appetite Fatigue and weakness Changes in how much you urinate Chest pain, if fluid builds up around the lining of the heart Shortness of breath, if fluid builds up in the lungs Swelling of feet and ankles High blood pressure (hypertension) that's difficult to control Headaches Difficulty sleeping Decreased mental sharpness Muscle twitches and cramps Persistent itching Metallic taste Signs and symptoms of kidney disease are often nonspecific, meaning they can also be caused by other illnesses. Because your kidneys can make up for lost function, signs and symptoms might not appear until irreversible damage has occurred. When to seek care Make an appointment with your health care provider if you have signs or symptoms of kidney disease. If you have a medical condition that increases your risk of kidney disease, your care provider is likely to monitor your kidney function with urine and blood tests and your blood pressure during regular office visits. Ask your provider whether these tests are necessary for you.",339,End Stage Renal Disease "including: Buzzing Roaring Clicking Hissing Humming Most people who have tinnitus have subjective tinnitus, or tinnitus that only you can hear. The noises of tinnitus may vary in pitch from a low roar to a high squeal, and you may hear it in one or both ears. In some cases, the sound can be so loud it interferes with your ability to concentrate or hear external sound. Tinnitus may be present all the time, or it may come and go. In rare cases, tinnitus can occur as a rhythmic pulsing or whooshing sound, often in time with your heartbeat. This is called pulsatile tinnitus. If you have pulsatile tinnitus, your doctor may be able to hear your tinnitus when he or she does an examination (objective tinnitus).",990,Tinnitus "Rhinophyma: Over time, rosacea can thicken the skin on the nose, causing the nose to appear bulbous (rhinophyma). This occurs more often in men than in women. Over time, rosacea can thicken the skin on the nose, causing the nose to appear bulbous (rhinophyma). Signs and symptoms of rosacea include: Facial blushing or flushing. Rosacea can cause a persistent blushing or flushing in the central part of your face. This sign of the condition may be difficult to see on brown and Black skin. Visible veins. Small blood vessels of your nose and cheeks break and become visible (spider veins). Swollen bumps. Many people with rosacea also develop pimples on their face that resemble acne. These bumps sometimes contain pus. Burning sensation. The skin of the affected area may feel hot and tender. Eye problems. Many people with rosacea also experience dry, irritated, swollen eyes and eyelids. This is known as ocular rosacea. In some people, the eye symptoms precede the skin symptoms. Enlarged nose.",863,Rosacea "Signs and symptoms of obstructive sleep apnea include: Excessive daytime sleepiness Loud snoring Observed episodes of stopped breathing during sleep Abrupt awakenings accompanied by gasping or choking Awakening with a dry mouth or sore throat Morning headache Difficulty concentrating during the day Mood changes, such as depression or irritability High blood pressure Decreased libido",691,Obstructive Sleep Apnea "The signs and symptoms of: Cushing syndrome can vary depending on the levels of excess cortisol. Common signs and symptoms of Cushing syndrome Weight gain and fatty tissue deposits, particularly around the midsection and upper back, in the face (moon face), and between the shoulders (buffalo hump) Pink or purple stretch marks (striae) on the skin of the abdomen, thighs, breasts and arms Thinning, fragile skin that bruises easily Slow healing of cuts, insect bites and infections Acne Signs and symptoms women with Cushing syndrome may experience Thicker or more visible body and facial hair (hirsutism) Irregular or absent menstrual periods Signs and symptoms men with Cushing syndrome may experience Decreased sex drive Decreased fertility Erectile dysfunction Other possible signs and symptoms of Cushing syndrome Severe fatigue Muscle weakness Depression, anxiety and irritability Loss of emotional control Cognitive difficulties New or worsened high blood pressure Headache Infections Skin darkening Bone loss, leading to fractures over time In children, impaired growth",260,Cushing Syndrome "Female reproductive system: The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. In many cases, gonorrhea infection causes no symptoms. Symptoms, however, can affect many sites in your body, but commonly appear in the genital tract. Gonorrhea affecting the genital tract Signs and symptoms of gonorrhea infection in men include: Painful urination Pus-like discharge from the tip of the penis Pain or swelling in one testicle Signs and symptoms of gonorrhea infection in women include: Increased vaginal discharge Painful urination Vaginal bleeding between periods, such as after vaginal intercourse Abdominal or pelvic pain Gonorrhea at other sites in the body Gonorrhea can also affect these parts of the body: Rectum. Signs and symptoms include anal itching, pus-like discharge from the rectum, spots of bright red blood on toilet tissue and having to strain during bowel movements. Eyes. Gonorrhea that affects your eyes can cause eye pain, sensitivity to light, and pus-like discharge from one or both eyes. Throat. Signs and symptoms of a throat infection might include a sore throat and swollen lymph nodes in the neck. Joints. If one or more joints become infected by bacteria (septic arthritis), the affected joints might be warm, red, swollen and extremely painful, especially during movement. When to see your doctor Make an appointment with your doctor if you notice any troubling signs or symptoms, such as a burning sensation when you urinate or a pus-like discharge from your penis, vagina or rectum. Also make an appointment with your doctor if your partner has been diagnosed with gonorrhea. You may not experience signs or symptoms that prompt you to seek medical attention. But without treatment, you can reinfect your partner even after he or she has been treated for gonorrhea.",423,Gonorrhea "The first symptoms may be similar to flu symptoms such as: Fever. Headache. Muscle aches or pain. Not wanting to eat. Tiredness. Swelling of the salivary glands usually starts within a few days. Symptoms may include: Swelling of one or both glands on the sides of the face. Pain or tenderness around the swelling. Less often, swelling of glands below the floor of the mouth.",655,Mumps "Some people have no symptoms in the early stages of avascular necrosis. As the condition worsens, affected joints might hurt only when putting weight on them. Eventually, you might feel the pain even when you're lying down. Pain can be mild or severe. It usually develops gradually. Pain associated with avascular necrosis of the hip might center on the groin, thigh or buttock. Besides the hip, the shoulder, knee, hand and foot can be affected. Some people develop avascular necrosis on both sides, such as in both hips or in both knees.",91,Avascular Necrosis "Lightheadedness or feeling faint: Unsteadiness or a loss of balance A feeling of floating, wooziness or heavy-headedness These feelings may be triggered or worsened by walking, standing up or moving your head. Your dizziness may be accompanied by nausea or be so sudden or severe that you need to sit or lie down. The episode may last seconds or days and may recur.",302,Dizziness "People with the disorder can: Have an unreasonably high sense of self-importance and require constant, excessive admiration. Feel that they deserve privileges and special treatment. Expect to be recognized as superior even without achievements. Make achievements and talents seem bigger than they are. Be preoccupied with fantasies about success, power, brilliance, beauty or the perfect mate. Believe they are superior to others and can only spend time with or be understood by equally special people. Be critical of and look down on people they feel are not important. Expect special favors and expect other people to do what they want without questioning them. Take advantage of others to get what they want. Have an inability or unwillingness to recognize the needs and feelings of others. Be envious of others and believe others envy them. Behave in an arrogant way, brag a lot and come across as conceited. Insist on having the best of everything — for instance, the best car or office. At the same time, people with narcissistic personality disorder have trouble handling anything they view as criticism. They can: Become impatient or angry when they don't receive special recognition or treatment. Have major problems interacting with others and easily feel slighted. React with rage or contempt and try to belittle other people to make themselves appear superior. Have difficulty managing their emotions and behavior. Experience major problems dealing with stress and adapting to change. Withdraw from or avoid situations in which they might fail. Feel depressed and moody because they fall short of perfection. Have secret feelings of insecurity, shame, humiliation and fear of being exposed as a failure.",667,Narcissistic Personality Disorder "Mild signs and symptoms: Itching in your ear canal Slight redness inside your ear Mild discomfort that's made worse by pulling on your outer ear (pinna or auricle) or pushing on the little ""bump"" in front of your ear (tragus) Some drainage of clear, odorless fluid Moderate progression More-intense itching Increasing pain More-extensive redness in your ear Excessive fluid drainage Feeling of fullness inside your ear and partial blockage of your ear canal by swelling, fluid and debris Decreased or muffled hearing Advanced progression Severe pain that might radiate to your face, neck or side of your head Complete blockage of your ear canal Redness or swelling of your outer ear Swelling in the lymph nodes in your neck Fever",959,Swimmers Ear "Some of the more common symptoms of a brain tumor in children include: Headaches, which may become more frequent and more severe Feeling of increased pressure in the head Unexplained nausea or vomiting Abrupt onset of vision problems, such double vision Other possible signs and symptoms, depending on the tumor location, include: A fuller soft spot (fontanel) on the skull in babies Seizures, especially when there's no history of seizures Abnormal eye movement Slurred speech Trouble swallowing Loss of appetite; or in babies, difficulty feeding Difficulty with balance Trouble walking Weakness or loss of sensation in an arm or a leg Weakness or drooping on one side on the face Confusion, irritability Memory problems Personality or behavior changes Hearing problems",729,Pediatric Brain Tumor "The signs and symptoms of two common types of pemphigus are as follows: Pemphigus vulgaris. This type usually begins with blisters in your mouth and then on your skin or genital mucous membranes. The blisters typically are painful but don't itch. Blisters in your mouth or throat may make it hard to swallow and eat. Pemphigus foliaceus. This type causes blisters on the chest, back and shoulders. The blisters tend to be more itchy than painful. Pemphigus foliaceus doesn't cause mouth blisters. Pemphigus is distinct from bullous pemphigoid, which is a blistering skin condition that affects older adults and may cause death.",732,Pemphigus "Children and adults: Initially, you may not even notice symptoms of oral thrush. Signs and symptoms may include: Creamy white lesions on your tongue, inner cheeks, and sometimes on the roof of your mouth, gums and tonsils Slightly raised lesions with a cottage cheese-like appearance Redness, burning or soreness that may be severe enough to cause difficulty eating or swallowing Slight bleeding if the lesions are rubbed or scraped Cracking and redness at the corners of your mouth A cottony feeling in your mouth Loss of taste Redness, irritation and pain under dentures (denture stomatitis) In severe cases, usually related to cancer or a weakened immune system from HIV/AIDS, the lesions may spread downward into your esophagus — the long, muscular tube stretching from the back of your mouth to your stomach (Candida esophagitis). If this occurs, you may experience difficulty swallowing and pain or feel as if food is getting stuck in your throat. Infants and breast-feeding mothers In addition to the distinctive white mouth lesions, infants may have trouble feeding or be fussy and irritable. They can pass the infection to their mothers during breast-feeding. The infection may then pass back and forth between the mother's breasts and the baby's mouth. Women whose breasts are infected with candida may experience these signs and symptoms: Unusually red, sensitive, cracked or itchy nipples Shiny or flaky skin on the darker, circular area around the nipple (areola) Unusual pain during nursing or painful nipples between feedings Stabbing pains deep within the breast When to see a doctor If you or your child develops white lesions inside the mouth, see your doctor or dentist. Thrush is uncommon in healthy older children, teenagers and adults, so if thrush develops, see your doctor to determine if further evaluation is needed to check for an underlying medical condition or other cause.",697,Oral Thrush "Typical signs and symptoms include: Pain. Transverse myelitis pain may begin suddenly in your lower back. Sharp pain may shoot down your legs or arms or around your chest or abdomen. Pain symptoms vary based on the part of your spinal cord that's affected. Abnormal sensations. Some people with transverse myelitis report sensations of numbness, tingling, coldness or burning. Some are especially sensitive to the light touch of clothing or to extreme heat or cold. You may feel as if something is tightly wrapping the skin of your chest, abdomen or legs. Weakness in your arms or legs. Some people notice heaviness in the legs, or that they're stumbling or dragging one foot. Others may develop severe weakness or even total paralysis. Bladder and bowel problems. This may include needing to urinate more frequently, urinary incontinence, difficulty urinating and constipation.",1007,Transverse Myelitis "Boils: Boils can occur anywhere on your skin, but appear mainly on the face, back of the neck, armpits, thighs and buttocks — hair-bearing areas where you're most likely to sweat or experience friction. Signs and symptoms of a boil usually include: A painful, red bump that starts out small and can enlarge to more than 2 inches (5 centimeters) Reddish or purplish, swollen skin around the bump An increase in the size of the bump over a few days as it fills with pus Development of a yellow-white tip that eventually ruptures and allows the pus to drain out Carbuncles A carbuncle is a cluster of boils that form a connected area of infection. Compared with single boils, carbuncles cause a deeper and more severe infection and are more likely to leave a scar. People who have a carbuncle often feel unwell in general and may experience a fever and chills.",122,Boils And Carbuncles "Signs and symptoms of TMJ disorders may include: Pain or tenderness of your jaw Pain in one or both of the temporomandibular joints Aching pain in and around your ear Difficulty chewing or pain while chewing Aching facial pain Locking of the joint, making it difficult to open or close your mouth TMJ disorders can also cause a clicking sound or grating sensation when you open your mouth or chew. But if there's no pain or limitation of movement associated with your jaw clicking, you probably don't need treatment for a TMJ disorder.",991,Tmj "Signs and symptoms of stroke include: Trouble speaking and understanding what others are saying. You may experience confusion, slur words or have difficulty understanding speech. Paralysis or numbness of the face, arm or leg. You may develop sudden numbness, weakness or paralysis in the face, arm or leg. This often affects just one side of the body. Try to raise both your arms over your head at the same time. If one arm begins to fall, you may be having a stroke. Also, one side of your mouth may droop when you try to smile. Problems seeing in one or both eyes. You may suddenly have blurred or blackened vision in one or both eyes, or you may see double. Headache. A sudden, severe headache, which may be accompanied by vomiting, dizziness or altered consciousness, may indicate that you're having a stroke. Trouble walking. You may stumble or lose your balance. You may also have sudden dizziness or a loss of coordination.",948,Stroke "Delayed ejaculation is divided into the following types based on symptoms: Lifelong vs. acquired. With lifelong delayed ejaculation, the problem is present from the time of sexual maturity. Acquired delayed ejaculation occurs after a period of normal sexual functioning. Generalized vs. situational. Generalized delayed ejaculation isn't limited to certain sex partners or certain kinds of stimulation. Situational delayed ejaculation occurs only under certain circumstances. These categories help in diagnosing an underlying cause and determining what might be the most effective treatment.",272,Delayed Ejaculation "Mild to moderate infection: The most common signs and symptoms of mild to moderate C. difficile infection are: Watery diarrhea three or more times a day for more than one day Mild abdominal cramping and tenderness Severe infection People who have a severe C. difficile infection tend to become dehydrated and may need to be hospitalized. C. difficile can cause the colon to become inflamed and sometimes form patches of raw tissue that can bleed or produce pus. Signs and symptoms of severe infection include: Watery diarrhea as often as 10 to 15 times a day Abdominal cramping and pain, which may be severe Rapid heart rate Dehydration Fever Nausea Increased white blood cell count Kidney failure Loss of appetite Swollen abdomen Weight loss Blood or pus in the stool C. difficile infection that is severe and sudden, an uncommon condition, may also cause intestinal inflammation leading to enlargement of the colon (also called toxic megacolon) and sepsis. Sepsis is a life-threatening condition that occurs when the body's response to an infection damages its own tissues. People who have these conditions are admitted to the intensive care unit.",163,C Difficile "Signs and symptoms of menorrhagia may include: Soaking through one or more sanitary pads or tampons every hour for several consecutive hours Needing to use double sanitary protection to control your menstrual flow Needing to wake up to change sanitary protection during the night Bleeding for longer than a week Passing blood clots larger than a quarter Restricting daily activities due to heavy menstrual flow Symptoms of anemia, such as tiredness, fatigue or shortness of breath",616,Menorrhagia "Symptoms of: Meniere's disease include: Regular dizzy spells. You have a spinning feeling that starts and stops suddenly. Vertigo may start without warning. It usually lasts 20 minutes to 12 hours, but not more than 24 hours. Serious vertigo can cause nausea. Hearing loss. Hearing loss in Meniere's disease may come and go, especially early on. Over time, hearing loss can be long-lasting and not get better. Ringing in the ear. Ringing in the ear is called tinnitus. Tinnitus is the term for when you have a ringing, buzzing, roaring, whistling or hissing sound in your ear. Feeling of fullness in the ear. People with Meniere's disease often feel pressure in the ear. This is called aural fullness. After a vertigo attack, symptoms get better and might go away for a while. Over time, how many vertigo attacks you have may lessen.",612,Menieres Disease "burning or scratchy sensation in your eyes: Stringy mucus in or around your eyes Sensitivity to light Eye redness A sensation of having something in your eyes Difficulty wearing contact lenses Difficulty with nighttime driving Watery eyes, which is the body's response to the irritation of dry eyes Blurred vision or eye fatigue",309,Dry Eyes "include: Headaches Seizures Vomiting Chest pains Fast, pounding or fluttering heartbeat (palpitations) Shortness of breath If your child has any of these signs or symptoms, seek emergency medical care.",477,High Blood Pressure In Children "Your symptoms might include: Stuffy or runny nose. Sneezing. Mucus in the throat. Cough. Nonallergic rhinitis most often doesn't cause an itchy nose, eyes or throat. That symptom is linked with allergies such as hay fever.",686,Nonallergic Rhinitis "a child can develop: Loud barking cough that's made worse by crying and coughing, as well as anxiety and distress, setting up a cycle of worsening symptoms. Fever. Hoarse voice. Noisy or labored breathing. Symptoms of croup are often worse at night and usually last for 3 to 5 days.",256,Croup "the most common signs and symptoms of uterine fibroids include: Heavy menstrual bleeding Menstrual periods lasting more than a week Pelvic pressure or pain Frequent urination Difficulty emptying the bladder Constipation Backache or leg pains Rarely, a fibroid can cause acute pain when it outgrows its blood supply, and begins to die. Fibroids are generally classified by their location. Intramural fibroids grow within the muscular uterine wall. Submucosal fibroids bulge into the uterine cavity. Subserosal fibroids project to the outside of the uterus.",1037,Uterine Fibroids "signs and symptoms may include: Worsening blood pressure control Protein in the urine Swelling of feet, ankles, hands or eyes Increased need to urinate Reduced need for insulin or diabetes medicine Confusion or difficulty concentrating Shortness of breath Loss of appetite Nausea and vomiting Persistent itching Fatigue",290,Diabetic Nephropathy General signs and symptoms common to a number of infectious diseases include: Fever Diarrhea Fatigue Muscle aches Coughing,520,Infectious Diseases "may have: An enlarged clitoris, which may resemble a penis Closed labia, or labia that include folds and resemble a scrotum Lumps that feel like testes in the fused labia Babies who are genetically male (with one X and one Y chromosome) may have: A condition in which the narrow tube that carries urine and semen (urethra) doesn't fully extend to the tip of the penis (hypospadias) An abnormally small penis with the urethral opening closer to the scrotum The absence of one or both testicles in what appears to be the scrotum Undescended testicles and an empty scrotum that has the appearance of a labia with or without a micropenis",38,Ambiguous Genitalia A runny nose: Persistent stuffiness Postnasal drip Decreased or absent sense of smell Loss of sense of taste Facial pain or headache Pain in your upper teeth A sense of pressure over your forehead and face Snoring Frequent nosebleeds,670,Nasal Polyps "Infants: Common signs and symptoms of hydrocephalus in infants include: Changes in the head An unusually large head A rapid increase in the size of the head A bulging or tense soft spot (fontanel) on the top of the head Physical signs and symptoms Nausea and vomiting Sleepiness or sluggishness (lethargy) Irritability Poor eating Seizures Eyes fixed downward (sunsetting of the eyes) Problems with muscle tone and strength Toddlers and older children Among toddlers and older children, signs and symptoms might include: Physical signs and symptoms Headache Blurred or double vision Abnormal eye movements Abnormal enlargement of a toddler's head Sleepiness or sluggishness Nausea or vomiting Unstable balance Poor coordination Poor appetite Loss of bladder control or frequent urination Behavioral and cognitive changes Irritability Change in personality Decline in school performance Delays or problems with previously acquired skills, such as walking or talking Young and middle-aged adults Common signs and symptoms in this age group include: Headache Sluggishness Loss of coordination or balance Loss of bladder control or a frequent urge to urinate Vision problems Decline in memory, concentration and other thinking skills that may affect job performance Older adults Among adults 60 years of age and older, the more common signs and symptoms of hydrocephalus are: Loss of bladder control or a frequent urge to urinate Memory loss Progressive loss of other thinking or reasoning skills Difficulty walking, often described as a shuffling gait or the feeling of the feet being stuck Poor coordination or balance",493,Hydrocephalus include: Neck or jaw pain Shoulder or arm pain A fast heartbeat Shortness of breath when you are physically active Nausea and vomiting Sweating Fatigue,662,Myocardial Ischemia "Signs and symptoms of cholangiocarcinoma include: Yellowing of your skin and the whites of your eyes (jaundice) Intensely itchy skin White-colored stools Fatigue Abdominal pain on the right side, just below the ribs Losing weight without trying Fever Night sweats Dark urine",202,Cholangiocarcinoma "Each person with: Down syndrome is an individual — intellectual and developmental problems may be mild, moderate or severe. Some people are healthy while others have significant health problems such as serious heart defects. Children and adults with Down syndrome have distinct facial features. Though not all people with Down syndrome have the same features, some of the more common features include: Flattened face Small head Short neck Protruding tongue Upward slanting eye lids (palpebral fissures) Unusually shaped or small ears Poor muscle tone Broad, short hands with a single crease in the palm Relatively short fingers and small hands and feet Excessive flexibility Tiny white spots on the colored part (iris) of the eye called Brushfield's spots Short height Infants with Down syndrome may be average size, but typically they grow slowly and remain shorter than other children the same age. Intellectual disabilities Most children with Down syndrome have mild to moderate cognitive impairment. Language is delayed, and both short and long-term memory is affected.",304,Down Syndrome "Other signs and symptoms might include: Loss of appetite and weight loss Joint and muscle pain Abdominal pain and gastrointestinal bleeding Weakness, fatigue or a general feeling of being unwell Rash or skin sores Pain, numbness, and tingling in your hands and feet",220,Churg Strauss Syndrome it might be accompanied by: Abdominal pain Fatigue Nausea and vomiting Yellowing of the skin and the whites of the eyes (jaundice),342,Enlarged Liver "A person with aphasia may: Speak in short or incomplete sentences Speak in sentences that don't make sense Substitute one word for another or one sound for another Speak unrecognizable words Have difficulty finding words Not understand other people's conversation Not understand what they read Write sentences that don't make sense Patterns of aphasia People with aphasia may have different strengths and weaknesses in their speech patterns. Sometimes these patterns are labeled as different types of aphasia, including: Broca's aphasia Wernicke aphasia Transcortical aphasia Conduction aphasia Mixed aphasia Global aphasia These patterns describe how well the person can understand what others say. They also describe how easy it is for the person to speak or to correctly repeat what someone else says. Aphasia may develop slowly over time. When that happens, the aphasia may be labeled with one of these names: Logopenic aphasia Semantic aphasia Agrammatism Many people with aphasia have patterns of speech difficulty that don't match these types. It may help to consider that each person with aphasia has unique symptoms, strengths and weaknesses rather than trying to label a particular type of aphasia.",66,Aphasia "AVM AVM: But some people with brain AVM may experience signs and symptoms other than bleeding, such as: AVM Seizures Headache or pain in one area of the head Muscle weakness or numbness in one part of the body Some people may experience more-serious neurological signs and symptoms, depending on the location of the AVM, including: AVM Severe headache Weakness, numbness or paralysis Vision loss Difficulty speaking Confusion or inability to understand others Severe unsteadiness Signs and symptoms of a brain AVM may begin at any age but usually emerge between ages 10 and 40. Brain AVMs can damage brain tissue over time. The effects slowly build and often cause symptoms in early adulthood. AVM AVM By middle age, however, brain AVMs tend to remain stable and are less likely to cause symptoms. AVM Research hasn't found that pregnancy increases the risk of hemorrhage for people with a brain AVM. However, more research needs to be done. AVM One severe type of brain AVM involves the vein of Galen. It causes signs and symptoms that emerge soon or immediately after birth. The major blood vessel involved in this type of brain AVM can cause fluid to build up in the brain and the head to swell. It can also cause swollen veins that are visible on the scalp, seizures, failure to thrive and congestive heart failure.",132,Brain Avm "s what it might look like: The top of the foot is usually twisted downward and inward, increasing the arch and turning the heel inward. The foot may be turned so severely that it actually looks as if it's upside down. The affected leg or foot may be slightly shorter. The calf muscles in the affected leg are usually underdeveloped. Despite its look, clubfoot itself doesn't cause any discomfort or pain.",224,Clubfoot "Babies with: Rett syndrome usually are born after an uncomplicated pregnancy and delivery. Most infants with Rett syndrome seem to grow and behave as expected for the first six months. After that, signs and symptoms start to appear. The most pronounced changes generally occur at 12 to 18 months of age, over a period of weeks or months. Symptoms and their severity vary greatly from child to child. The main signs and symptoms include: Slowed growth. Brain growth slows after birth. Smaller than usual head size (microcephaly) is sometimes the first sign that a child has Rett syndrome. As children get older, there is delayed growth in other parts of the body. Loss of movement and coordination abilities. The first signs often include reduced hand control and a decreasing ability to crawl or walk. At first, this loss of abilities occurs rapidly, and then it continues more gradually. Eventually muscles become weak or stiff, with unusual movement and positioning. Loss of communication abilities. Children with Rett syndrome typically begin to lose the ability to speak, to make eye contact and to communicate in other ways. They may become disinterested in other people, toys and their surroundings. Some children have rapid changes, such as a sudden loss of language. Over time, children may gradually regain eye contact and develop nonverbal communication skills. Unusual hand movements. Children with Rett syndrome usually develop repetitive, purposeless hand movements, which differ from child to child. Hand movements may include hand-wringing, squeezing, clapping, tapping or rubbing. Other signs and symptoms can include: Unusual eye movements. Children with Rett syndrome tend to have unusual eye movements, such as intense staring, blinking, crossed eyes or closing one eye at a time. Breathing problems. These include breath holding, rapid breathing (hyperventilation), forcefully blowing out air or saliva, and swallowing air. These problems tend to occur during waking hours. Other breathing disturbances such as shallow breathing or short periods of stopping breathing (apnea) can occur during sleep. Irritability and crying. Children with Rett syndrome may become increasingly agitated and irritable as they get older. Periods of crying or screaming may begin suddenly, for no apparent reason, and last for hours. Some children may experience fears and anxiety. Other unusual behaviors. These may include, for example, sudden, odd facial expressions and long bouts of laughter, hand licking, and grasping of hair or clothing. Intellectual disabilities. Loss of skills may be connected to losing the ability to think, understand and learn. Seizures. Most people who have Rett syndrome experience seizures at some time during their lives. Multiple seizure types may occur and are associated with changes on an electroencephalogram (EEG). Sideways curvature of the spine (scoliosis). Scoliosis is common with Rett syndrome. It typically begins between 8 and 11 years of age and progresses with age. Surgery may be required if the curvature is severe. Irregular heartbeat. This is a life-threatening problem for many children and adults with Rett syndrome and can result in sudden death. Sleep disturbances. Problems with sleep patterns can include irregular sleep times, falling asleep during the day and being awake at night, or waking in the night with crying or screaming. Other symptoms. A variety of other symptoms can occur, such as a decreased response to pain; small hands and feet that are usually cold; problems with chewing and swallowing; problems with bowel function; and teeth grinding. Stages of Rett syndrome Rett syndrome is commonly divided into four stages: Stage 1: Early onset. Signs and symptoms are subtle and easily overlooked during the first stage, which starts between 6 and 18 months of age. Stage 1 can last for a few months or a year. Babies in this stage may show less eye contact and start to lose interest in toys. They may also have delays in sitting or crawling. Stage 2: Rapid deterioration. Starting between 1 and 4 years of age, children lose the ability to perform skills they previously had. This loss can be rapid or more gradual, occurring over weeks or months. Symptoms of Rett syndrome occur, such as slowed head growth, abnormal hand movements, hyperventilating, screaming or crying for no apparent reason, problems with movement and coordination, and a loss of social interaction and communication. Stage 3: Plateau. The third stage usually begins between the ages of 2 and 10 years, and it can last for many years. Although problems with movement continue, behavior may slightly improve, with less crying and irritability, and there may be some improvement in hand use and communication. Seizures may begin in this stage and generally don't occur before the age of 2. Stage 4: Late motor deterioration. This stage usually begins after the age of 10 and can last for years or decades. It's marked by reduced mobility, muscle weakness, joint contractures and scoliosis. Understanding, communication and hand skills generally remain stable or improve slightly, and seizures may occur less often.",855,Rett Syndrome "s foot: Athlete's foot is a fungal infection that causes scaly rash that may itch, sting or burn. Athlete's foot can affect one or both feet. Common signs and symptoms are: Scaly, peeling or cracked skin between the toes Itchiness, especially right after taking off shoes and socks Inflamed skin that might appear reddish, purplish or grayish, depending on your skin color Burning or stinging Blisters Dry, scaly skin on the bottom of the foot that extends up the side",81,Athletes Foot "MRSA: Staph skin infections, including MRSA, generally start as swollen, painful red bumps that might look like pimples or spider bites. The affected area might be: MRSA Warm to the touch Full of pus or other drainage Accompanied by a fever These red bumps can quickly turn into deep, painful boils (abscesses) that require surgical draining. Sometimes the bacteria remain confined to the skin. But they can also burrow deep into the body, causing potentially life-threatening infections in bones, joints, surgical wounds, the bloodstream, heart valves and lungs.",651,Mrsa Ingrown toenail symptoms include: Pain and tenderness Inflamed skin Swelling Infection,525,Ingrown Toenails "Common symptoms of hemifacial spasm include twitching or contracting of muscles in the face that are usually: On one side of the face Uncontrollable Painless These contractions often start in the eyelid, then may progress and affect the cheek and mouth on the same side of the face. At first, hemifacial spasms come and go. But eventually, usually over the course of several months to a few years, they occur almost constantly. Occasionally, hemifacial spasms may occur on both sides of the face. However, the twitching doesn't occur on both sides of the face at the same time. Causes Hemifacial spasm is most often caused by a blood vessel touching a facial nerve. It can also be caused by a facial nerve injury or a tumor. Sometimes there's no identifiable cause. Hemifacial spasm may sometimes be triggered by: Moving the muscles in the face Anxiety Stress Fatigue By Mayo Clinic Staff By Mayo Clinic Staff Hemifacial spasm care at Mayo Clinic",458,Hemifacial Spasm Its signs and symptoms may include: An irritated area of skin that tends to expand Swelling Tenderness Pain Warmth Fever Chills Spots Blisters Skin dimpling,181,Cellulitis "Signs and symptoms of calciphylaxis include: Large purple net-like patterns on skin Deep, very painful lumps that ulcerate creating open sores with black-brown crust that fails to heal — typically in skin areas with high fat content, such as the stomach and thigh, although they can occur anywhere Infections from wounds that don't heal Causes The exact cause of calciphylaxis is unknown, but recent studies have revealed that most people with the condition have abnormalities in blood-clotting factors. Blood-clotting factors are substances in your blood that help stop bleeding. These abnormalities can lead to small blood clots forming more often than they normally would. In addition, people with calciphylaxis have an imbalance in the metabolism of calcium. This causes calcium to be deposited in the smallest parts of the arteries (arterioles), which eventually leads to the formation of blood clots in the arterioles. Blood clots can cause fat tissues and skin to be deprived of oxygen and nourishment.",164,Calciphylaxis "Signs and symptoms are similar to those of the flu and include: Fever Chills Loss of appetite Sweats Weakness Fatigue Joint, muscle and back pain Headache Brucellosis symptoms may disappear for weeks or months and then return. Some people have chronic brucellosis and experience symptoms for years, even after treatment. Long-term signs and symptoms may include: Fatigue Recurrent fevers Inflammation of the inner lining of the heart chambers (endocarditis) Joint inflammation (arthritis) Arthritis of the spinal bones (spondylitis) Arthritis of joints where the spine and pelvis connect (sacroiliitis)",152,Brucellosis "CAH: Classic CAH Signs and symptoms of classic CAH may include: CAH Insufficient cortisol. Classic CAH causes the body to produce an insufficient amount of cortisol. This can cause problems maintaining normal blood pressure, blood sugar and energy levels, and cause problems during physical stress such as illness. Adrenal crisis. People with classic CAH can be seriously affected by a lack of cortisol, aldosterone or both. This is known as an adrenal crisis, and it can be life-threatening. Atypical genitalia. Female infants may have atypical genitalia appearance, such as an enlarged clitoris that may resemble a penis, and a partially closed labia resembling a scrotum. The urinary opening (urethra) and the vagina may be only one opening instead of two separate openings. The uterus, fallopian tubes and ovaries usually develop typically. Male infants usually have typical-appearing genitals. Excess androgen. An excess of the male sex hormone androgen can result in short height and early puberty for both males and females. Pubic hair and other signs of puberty may appear at a very early age. Severe acne also may occur. Excess androgen hormones in females may result in facial hair, excessive body hair and a deepening voice. Altered growth. Rapid growth may occur during childhood with an advanced bone age. Final height may be shorter than average. Fertility issues. These can include irregular menstrual periods, or not having any at all, and having infertility problems in females. Fertility issues can sometimes occur in males. Nonclassic CAH Often there are no symptoms of nonclassic CAH when a baby is born. Some people with nonclassic CAH never have symptoms. The condition is not identified on routine infant blood screening and usually becomes evident in late childhood or early adulthood. Cortisol may be the only hormone that's deficient. CAH CAH Females who have nonclassic CAH may have typical-appearing genitals at birth. Later in life, they may experience: CAH Irregular menstrual periods, or not having any at all, and problems getting pregnant Masculine characteristics such as facial hair, excessive body hair and a deepening voice In both females and males, signs of nonclassic CAH may also include: CAH Early appearance of pubic hair and other signs of early puberty Severe acne Rapid growth during childhood with an advanced bone age and shorter than expected final height",240,Congenital Adrenal Hyperplasia "When to see a doctor: Seek medical advice if you have a menstrual flow despite the insertion of a tampon, or if you have severe pain with menstruation or experience repeated miscarriages.",303,Double Uterus "signs and symptoms of bone metastasis include: Bone pain Broken bones Urinary incontinence Bowel incontinence Weakness in the legs or arms High levels of calcium in the blood (hypercalcemia), which can cause nausea, vomiting, constipation and confusion",125,Bone Metastasis "are the hallmark sign of: Tourette syndrome. They can range from mild to severe. Severe symptoms might significantly interfere with communication, daily functioning and quality of life. Tics are classified as: Simple tics. These sudden, brief and repetitive tics involve a limited number of muscle groups. Complex tics. These distinct, coordinated patterns of movements involve several muscle groups. Tics can also involve movement (motor tics) or sounds (vocal tics). Motor tics usually begin before vocal tics do. But the spectrum of tics that people experience is diverse. Common motor tics seen in Tourette syndrome Simple tics Complex tics Eye blinking Touching or smelling objects Head jerking Repeating observed movements Shoulder shrugging Stepping in a certain pattern Eye darting Obscene gesturing Nose twitching Bending or twisting Mouth movements Hopping Common motor tics seen in Tourette syndrome Simple tics Complex tics Simple tics Complex tics Simple tics Complex tics Eye blinking Touching or smelling objects Head jerking Repeating observed movements Shoulder shrugging Stepping in a certain pattern Eye darting Obscene gesturing Nose twitching Bending or twisting Mouth movements Hopping Eye blinking Touching or smelling objects Eye blinking Touching or smelling objects Head jerking Repeating observed movements Head jerking Repeating observed movements Shoulder shrugging Stepping in a certain pattern Shoulder shrugging Stepping in a certain pattern Eye darting Obscene gesturing Eye darting Obscene gesturing Nose twitching Bending or twisting Nose twitching Bending or twisting Mouth movements Hopping Mouth movements Hopping Common vocal tics seen in Tourette syndrome Simple tics Complex tics Grunting Repeating one's own words or phrases Coughing Repeating others' words or phrases Throat clearing Using vulgar, obscene or swear words Barking Common vocal tics seen in Tourette syndrome Simple tics Complex tics Simple tics Complex tics Simple tics Complex tics Grunting Repeating one's own words or phrases Coughing Repeating others' words or phrases Throat clearing Using vulgar, obscene or swear words Barking Grunting Repeating one's own words or phrases Grunting Repeating one's own words or phrases Coughing Repeating others' words or phrases Coughing Repeating others' words or phrases Throat clearing Using vulgar, obscene or swear words Throat clearing Using vulgar, obscene or swear words Barking Barking In addition, tics can: Vary in type, frequency and severity Worsen if you're ill, stressed, anxious, tired or excited Occur during sleep Change over time Worsen in the early teenage years and improve during the transition into adulthood Before the onset of motor or vocal tics, you'll likely experience an uncomfortable bodily sensation (premonitory urge) such as an itch, a tingle or tension. Expression of the tic brings relief. With great effort, some people with Tourette syndrome can temporarily stop or hold back a tic.",998,Tourette Syndrome Chest pain or discomfort: Confusion Dizziness or lightheadedness Fainting or near fainting Fatigue Shortness of breath Slower pulse (bradycardia),906,Sick Sinus Syndrome "Signs and symptoms of tricuspid valve regurgitation may include: Fatigue Irregular heart rhythms (arrhythmias) Pulsing in the neck Shortness of breath with activity Swelling in the belly area (abdomen), legs or neck veins",1014,Tricuspid Valve Regurgitation "CAS: Delayed onset of first words A limited number of spoken words The ability to form only a few consonant or vowel sounds These symptoms are usually noticed between ages 18 months and 2 years, and may indicate suspected CAS. CAS As children produce more speech, usually between ages 2 and 4, characteristics that likely indicate CAS include: CAS Vowel and consonant distortions Separation of syllables in or between words Voicing errors, such as ""pie"" sounding like ""bye"" Many children with CAS have difficulty getting their jaws, lips and tongues to the correct positions to make a sound, and they may have difficulty moving smoothly to the next sound. CAS Many children with CAS also have language problems, such as reduced vocabulary or difficulty with word order. CAS Some symptoms may be unique to children with CAS and can be helpful to diagnose the problem. However, some symptoms of CAS are also symptoms of other types of speech or language disorders. It's difficult to diagnose CAS if a child has only symptoms that are found both in CAS and in other types of speech or language disorders. CAS CAS CAS CAS Some characteristics, sometimes called markers, help distinguish CAS from other types of speech disorders. Those particularly associated with CAS include: CAS CAS Difficulty moving smoothly from one sound, syllable or word to another Groping movements with the jaw, lips or tongue to make the correct movement for speech sounds Vowel distortions, such as attempting to use the correct vowel, but saying it incorrectly Using the wrong stress in a word, such as pronouncing ""banana"" as ""BUH-nan-uh"" instead of ""buh-NAN-uh"" Using equal emphasis on all syllables, such as saying ""BUH-NAN-UH"" Separation of syllables, such as putting a pause or gap between syllables Inconsistency, such as making different errors when trying to say the same word a second time Difficulty imitating simple words Inconsistent voicing errors, such as saying ""down"" instead of ""town"" Other characteristics are seen in most children with speech or language problems and aren't helpful in distinguishing CAS. Characteristics seen both in children with CAS and in children with other types of speech or language disorders include: CAS CAS Babbling less or making fewer vocal sounds than is typical between the ages of 7 to 12 months old Speaking first words late (after ages 12 to 18 months old) Using a limited number of consonants and vowels Frequently leaving out (omitting) sounds Using speech that is difficult to understand speech Other speech disorders sometimes confused with CAS Some speech sound disorders often get confused with CAS because some of the characteristics may overlap. These speech sound disorders include articulation disorders, phonological disorders and dysarthria. CAS A child who has trouble learning how to make specific sounds, but doesn't have trouble planning or coordinating the movements to speak, may have an articulation or phonological disorder. Articulation and phonological disorders are more common than CAS. CAS Articulation or phonological speech errors may include: Substituting sounds, such as saying ""fum"" instead of ""thumb,"" ""wabbit"" instead of ""rabbit"" or ""tup"" instead of ""cup"" Leaving out (omitting) final consonants, such as saying ""duh"" instead of ""duck"" or ""uh"" instead of ""up"" Stopping the airstream, such as saying ""tun"" instead of ""sun"" or ""doo"" instead of ""zoo"" Simplifying sound combinations, such as saying ""ting"" instead of ""string"" or ""fog"" instead of ""frog"" Dysarthria is a motor speech disorder that is due to weakness, spasticity or inability to control the speech muscles. Making speech sounds is difficult because the speech muscles can't move as far, as quickly or as strongly as normal. People with dysarthria may also have a hoarse, soft or even strained voice, or slurred or slow speech. Dysarthria is often easier to identify than CAS. However, when dysarthria is caused by damage to certain areas of the brain that affect coordination, it can be difficult to determine the differences between CAS and dysarthria.",197,Childhood Apraxia Of Speech "the most common signs and symptoms are: Fever and chills Muscle aches or pain Headache Some people also experience: Nausea Stomach pain Vomiting Diarrhea As the disease progresses, it can lead to damaged lung tissues, fluid build-up in the lungs, and serious problems with lung and heart function. Signs and symptoms may include: Cough Difficulty breathing Low blood pressure Irregular heart rate",441,Hantavirus Pulmonary Syndrome Signs and symptoms of hypothyroidism include: Fatigue Increased sensitivity to cold Increased sleepiness Dry skin Constipation Muscle weakness Problems with memory or concentration Overactive thyroid (hyperthyroidism) Signs and symptoms of hyperthyroidism include: Weight loss Rapid heartbeat (tachycardia) Increased sensitivity to heat Excess sweating Tremors Irritability and nervousness Muscle weakness Frequent bowel movements Changes in menstrual patterns Sleep difficulty High blood pressure Increased appetite Children with hyperthyroidism might also have the following: Rapid growth in height Changes in behavior Bone growth that outpaces expected growth for the child's age Obstructive goiter The size or position of a goiter may obstruct the airway and voice box. Signs and symptoms may include: Difficulty swallowing Difficulty breathing with exertion Cough Hoarseness Snoring,421,Goiter "they may include: Increased thirst. Frequent urination. Increased hunger. Unintended weight loss. Fatigue. Blurred vision. Slow-healing sores. Frequent infections. Numbness or tingling in the hands or feet. Areas of darkened skin, usually in the armpits and neck.",1024,Type 2 Diabetes "Stretch marks in pregnancy: Stretch marks in pregnancy Stretch marks are common in pregnancy, especially during the last trimester. They often fade but don't usually disappear. Widespread stretch marks Stretch marks can cover large areas of the body, but it happens rarely. This can result from corticosteroid medicine use or a disease such as Cushing syndrome. Stretch marks don't all look alike. They vary depending on how long you've had them, what caused them, where they are on your body and the type of skin you have. Common variations include: Indented streaks or lines on the abdomen, breasts, hips, buttocks or other places on the body Pink, red, discolored, black, blue or purple streaks Bright streaks that fade to a lighter color Streaks covering large areas of the body",947,Stretch Marks "Abortive polio: About 5% of people with the poliovirus get a mild version of the disease called abortive poliomyelitis. This leads to flu-like symptoms that last 2 to 3 days. These include: Fever Headache Muscle aches Sore throat Stomachache Loss of appetite Nausea Vomiting Nonparalytic polio A more severe form of the disease, called nonparalytic polio, affects about 1% of those infected. While the illness lasts longer than a few days, it doesn't cause paralysis. Besides having more-severe flu-like symptoms, nonparalytic polio symptoms may include: Neck pain or stiffness Aches or stiffness in the arms or legs Severe headache A second phase of symptoms may follow, or a person may seem to be getting better for a few days before a second phase starts. These symptoms include: Stiffness of the spine and neck Decreased reflexes Muscle weakness Paralytic polio This most serious form of the disease is rare. The disease begins much like nonparalytic polio. But it progresses to more-severe signs and symptoms, including: Intense pain Extreme sensitivity to touch Tingling or pricking sensations Muscles spasms or twitching Muscles weakness progressing to a limp paralysis Any combination of limbs may experience paralysis. But paralysis of one leg is most common, followed by paralysis of one arm. Depending on the severity of disease, other signs or symptoms may include: Paralysis of muscles involved in breathing Difficulty swallowing Post-polio syndrome Post-polio syndrome is the appearance of new signs or symptoms or the progression of problems. This usually happens decades after having polio. Common signs and symptoms include: Progressive muscle or joint weakness and pain Fatigue Muscle wasting Breathing or swallowing problems Sleep-related breathing disorders, such as sleep apnea Lowered tolerance of cold temperatures",770,Polio "Symptoms of coarctation of the aorta in infants include: Difficulty breathing Difficulty feeding Heavy sweating Irritability Pale skin Symptoms of coarctation of the aorta after infancy commonly include: Chest pain Headaches High blood pressure Leg cramps or cold feet Muscle weakness Nosebleeds Depending on where the coarctation is located, blood pressure may be high in the arms and low in the legs and ankles. Coarctation of the aorta often occurs with other heart defects. Other symptoms depend on the type of congenital heart defect.",227,Coarctation Of The Aorta "re usually mild at first and resemble those of a common cold: Runny nose Nasal congestion Red, watery eyes Fever Cough After a week or two, signs and symptoms worsen. Thick mucus accumulates inside your airways, causing uncontrollable coughing. Severe and prolonged coughing attacks may: Provoke vomiting Result in a red or blue face Cause extreme fatigue End with a high-pitched ""whoop"" sound during the next breath of air However, many people don't develop the characteristic whoop. Sometimes, a persistent hacking cough is the only sign that an adolescent or adult has whooping cough. Infants may not cough at all. Instead, they may struggle to breathe, or they may even temporarily stop breathing.",1070,Whooping Cough "Signs and symptoms could include: Pale gray or blue lips, tongue or fingernails (cyanosis) Rapid breathing Swelling in the legs, belly or areas around the eyes Shortness of breath during feedings, leading to poor weight gain Less-serious congenital heart defects may not be diagnosed until later in childhood. Signs and symptoms of congenital heart defects in older children may include: Easily becoming short of breath during exercise or activity Easily tiring during exercise or activity Fainting during exercise or activity Swelling in the hands, ankles or feet",242,Congenital Heart Defects Children "The signs and symptoms of: Takayasu's arteritis often occur in two stages. Stage 1 In the first stage, you're likely to feel unwell with: Fatigue Unintended weight loss Muscle and joint aches and pains Mild fever, sometimes accompanied by night sweats Not everyone has these early signs and symptoms. It's possible for inflammation to damage arteries for years before you realize something is wrong. Stage 2 During the second stage, inflammation causes arteries to narrow so less blood and oxygen and fewer nutrients reach your organs and tissues. Stage 2 signs and symptoms may include: Weakness or pain in your limbs with use A weak pulse, difficulty getting a blood pressure or a difference in blood pressure between your arms Lightheadedness, dizziness or fainting Headaches or visual changes Memory problems or trouble thinking Chest pain or shortness of breath High blood pressure Diarrhea or blood in your stool Too few red blood cells (anemia)",967,Takayasus Arteritis "Not seeing or feeling a testicle where you would expect it to be in the scrotum is the main sign of an undescended testicle. Testicles form in the abdomen during fetal development. During the last couple of months of normal fetal development, the testicles gradually descend from the abdomen through a tube-like passageway in the groin (inguinal canal) into the scrotum. With an undescended testicle, that process stops or is delayed.",1030,Undescended Testicle "Signs and symptoms of: Hirschsprung's disease vary with the severity of the condition. Usually signs and symptoms appear shortly after birth, but sometimes they're not apparent until later in life. Typically, the most obvious sign is a newborn's failure to have a bowel movement within 48 hours after birth. Other signs and symptoms in newborns may include: Swollen belly Vomiting, including vomiting a green or brown substance Constipation or gas, which might make a newborn fussy Diarrhea Delayed passage of meconium — a newborn's first bowel movement In older children, signs and symptoms can include: Swollen belly Chronic constipation Gas Failure to thrive Fatigue",481,Hirschsprungs Disease "Osteoarthritis of the hip: The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. In osteoarthritis of the spine, disks narrow and bone spurs form. Most bone spurs cause no signs or symptoms. You might not realize you have bone spurs until an X-ray for another condition reveals the growths. In some cases, though, bone spurs can cause pain and loss of motion in your joints. Specific symptoms depend on where the bone spurs are. Examples include: Knee. Bone spurs in your knee can make it painful to extend and bend your leg. Spine. On your vertebrae, bone spurs can narrow the space that contains your spinal cord. These bone spurs can pinch the spinal cord or its nerve roots and can cause weakness or numbness in your arms or legs. Hip. Bone spurs can make it painful to move your hip, although you might feel the pain in your knee. Depending on their placement, bone spurs can reduce the range of motion in your hip joint.",126,Bone Spurs "GI GI: Overt bleeding might show up as: Vomiting blood, which might be red or might be dark brown and resemble coffee grounds in texture Black, tarry stool Rectal bleeding, usually in or with stool With occult bleeding, you might have: Lightheadedness Difficulty breathing Fainting Chest pain Abdominal pain Symptoms of shock If your bleeding starts abruptly and progresses rapidly, you could go into shock. Signs and symptoms of shock include: Drop in blood pressure Not urinating or urinating infrequently, in small amounts Rapid pulse Unconsciousness",404,Gastrointestinal Bleeding "nearly every day and may include: Feelings of sadness, tearfulness, emptiness or hopelessness Angry outbursts, irritability or frustration, even over small matters Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports Sleep disturbances, including insomnia or sleeping too much Tiredness and lack of energy, so even small tasks take extra effort Reduced appetite and weight loss or increased cravings for food and weight gain Anxiety, agitation or restlessness Slowed thinking, speaking or body movements Feelings of worthlessness or guilt, fixating on past failures or self-blame Trouble thinking, concentrating, making decisions and remembering things Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts or suicide Unexplained physical problems, such as back pain or headaches For many people with depression, symptoms usually are severe enough to cause noticeable problems in day-to-day activities, such as work, school, social activities or relationships with others. Some people may feel generally miserable or unhappy without really knowing why. Depression symptoms in children and teens Common signs and symptoms of depression in children and teenagers are similar to those of adults, but there can be some differences. In younger children, symptoms of depression may include sadness, irritability, clinginess, worry, aches and pains, refusing to go to school, or being underweight. In teens, symptoms may include sadness, irritability, feeling negative and worthless, anger, poor performance or poor attendance at school, feeling misunderstood and extremely sensitive, using recreational drugs or alcohol, eating or sleeping too much, self-harm, loss of interest in normal activities, and avoidance of social interaction. Depression symptoms in older adults Depression is not a normal part of growing older, and it should never be taken lightly. Unfortunately, depression often goes undiagnosed and untreated in older adults, and they may feel reluctant to seek help. Symptoms of depression may be different or less obvious in older adults, such as: Memory difficulties or personality changes Physical aches or pain Fatigue, loss of appetite, sleep problems or loss of interest in sex — not caused by a medical condition or medication Often wanting to stay at home, rather than going out to socialize or doing new things Suicidal thinking or feelings, especially in older men",278,Depression "Signs and symptoms of geographic tongue may include: Smooth, red, irregularly shaped patches (lesions) on the top or side of your tongue Frequent changes in the location, size and shape of lesions Discomfort, pain or burning sensation in some cases, most often related to eating spicy or acidic foods Many people with geographic tongue have no symptoms. Geographic tongue can continue for days, months or years. The problem often resolves on its own but may appear again at a later time. When to see a doctor Geographic tongue is a minor — although sometimes uncomfortable — condition. However, lesions on the tongue may indicate other more-serious conditions of the tongue or diseases affecting the body in general. If you have lesions on the tongue that don't resolve within 10 days, see your doctor or dentist.",411,Geographic Tongue "Early signs and symptoms: Schizophrenia signs and symptoms in children and teenagers are similar to those in adults, but the condition may be more difficult to recognize in this age group. Early signs and symptoms may include problems with thinking, behavior and emotions. Thinking: Problems with thinking and reasoning Bizarre ideas or speech Confusing dreams or television for reality Behavior: Withdrawal from friends and family Trouble sleeping Lack of motivation — for example, showing up as a drop in performance at school Not meeting daily expectations, such as bathing or dressing Bizarre behavior Violent or aggressive behavior or agitation Recreational drug or nicotine use Emotions: Irritability or depressed mood Lack of emotion, or emotions inappropriate for the situation Strange anxieties and fears Excessive suspicion of others Later signs and symptoms As children with schizophrenia age, more typical signs and symptoms of the disorder begin to appear. Signs and symptoms may include: Delusions. These are false beliefs that are not based in reality. For example, you think that you're being harmed or harassed; that certain gestures or comments are directed at you; that you have exceptional ability or fame; that another person is in love with you; or that a major catastrophe is about to occur. Delusions occur in most people with schizophrenia. Hallucinations. These usually involve seeing or hearing things that don't exist. Yet for the person with schizophrenia, hallucinations have the full force and impact of a normal experience. Hallucinations can be in any of the senses, but hearing voices is the most common hallucination. Disorganized thinking. Disorganized thinking is inferred from disorganized speech. Effective communication can be impaired, and answers to questions may be partially or completely unrelated. Rarely, speech may include putting together meaningless words that can't be understood, sometimes known as word salad. Extremely disorganized or abnormal motor behavior. This may show in several ways, from childlike silliness to unpredictable agitation. Behavior is not focused on a goal, which makes it hard to do tasks. Behavior can include resistance to instructions, inappropriate or bizarre posture, a complete lack of response, or useless and excessive movement. Negative symptoms. This refers to reduced or lack of ability to function normally. For example, the person may neglect personal hygiene or appear to lack emotion — doesn't make eye contact, doesn't change facial expressions, speaks in a monotone, or doesn't add hand or head movements that normally occur when speaking. Also, the person may avoid people and activities or lack the ability to experience pleasure. Compared with schizophrenia symptoms in adults, children and teens may be: Less likely to have delusions More likely to have visual hallucinations Symptoms may be difficult to interpret When childhood schizophrenia begins early in life, symptoms may build up gradually. Early signs and symptoms may be so vague that you can't recognize what's wrong. Some early signs can be mistaken for typical development during early teen years, or they could be symptoms of other mental or physical conditions. As time goes on, signs may become more severe and more noticeable. Eventually, your child may develop the symptoms of psychosis, including hallucinations, delusions and difficulty organizing thoughts. As thoughts become more disorganized, there's often a ""break from reality"" (psychosis) frequently requiring hospitalization and treatment with medication.",200,Childhood Schizophrenia "Early illness: Early symptoms include: Fever that starts low and increases throughout the day, possibly reaching as high as 104 degrees Fahrenheit (40 degrees Celsius). Chills. Headache. Weakness and fatigue. Muscle aches. Stomach pain. Diarrhea or constipation. Rash. People also may have a cough, loss of appetite and sweating. Later illness A few weeks after symptoms start, the illness can cause problems in the intestines. People may have: Stomach pain. Very swollen stomach. An infection caused by gut bacteria spreading throughout the body, called sepsis. In very serious cases, people may: Become confused. Not be able to pay attention to anything around them. Not be able to react to the world around them. These are life-threatening complications. In some people, symptoms may return up to a few weeks after the fever has gone away.",1027,Typhoid Fever "Symptoms of a blocked tear duct include: Excessive tearing Redness of the white part of the eye Recurrent eye infection or inflammation, known as pink eye Painful swelling near the inside corner of the eye Crusting of the eyelids Mucus or pus discharge from the lids and surface of the eye Blurred vision",118,Blocked Tear Duct Symptoms might include: Being very thirsty Urinating often Feeling a need to throw up and throwing up Having stomach pain Being weak or tired Being short of breath Having fruity-scented breath Being confused More-certain signs of diabetic ketoacidosis — which can show up in home blood and urine test kits — include: High blood sugar level High ketone levels in urine,289,Diabetic Ketoacidosis "s disease symptoms include: Tingling or numbness in the hands or feet. Pale, reddish or blue-tinted hands or feet. Pain that may come and go in your legs and feet or in your arms and hands. This pain may occur when you use your hands or feet and eases when you stop that activity (claudication), or when you're at rest. Inflammation along a vein just below the skin's surface (due to a blood clot in the vein). Fingers and toes that turn pale when exposed to cold (Raynaud's phenomenon). Painful open sores on your fingers and toes.",155,Buergers Disease "The four main characteristics of: Henoch-Schonlein purpura include: Rash (purpura). Reddish-purple spots that look like bruises develop on the buttocks, legs and feet. The rash can also appear on the arms, face and trunk and may be worse in areas of pressure, such as the sock line and waistline. Swollen, sore joints (arthritis). People with Henoch-Schonlein purpura often have pain and swelling around the joints — mainly in the knees and ankles. Joint pain sometimes precedes the classical rash by one or two weeks. These symptoms subside when the disease clears and leave no lasting damage. Digestive tract symptoms. Many children with Henoch-Schonlein purpura develop belly pain, nausea, vomiting and bloody stools. These symptoms sometimes occur before the rash appears. Kidney involvement. Henoch-Schonlein purpura can also affect the kidneys. In most cases, this shows up as protein or blood in the urine, which you may not even know is there unless you have a urine test done. Usually this goes away once the illness passes, but some people develop persistent kidney disease.",463,Henoch Schonlein Purpura "Carcinoid tumors in the lungs: Signs and symptoms of carcinoid lung tumors include: Chest pain Wheezing Shortness of breath Diarrhea Redness or a feeling of warmth in your face and neck (skin flushing) Weight gain, particularly around the midsection and upper back Pink or purple marks on the skin that look like stretch marks Carcinoid tumors in the digestive tract Signs and symptoms of carcinoid tumors in the digestive tract include: Abdominal pain Diarrhea Nausea, vomiting and inability to pass stool due to intestinal blockage (bowel obstruction) Rectal bleeding Rectal pain Redness or a feeling of warmth in your face and neck (skin flushing)",169,Carcinoid Tumors "Carpal tunnel syndrome symptoms usually start gradually and include: Tingling or numbness. You may notice tingling and numbness in the fingers or hand. Usually the thumb and index, middle or ring fingers are affected, but not the little finger. You might feel a sensation like an electric shock in these fingers. The sensation may travel from the wrist up the arm. These symptoms often occur while holding a steering wheel, phone or newspaper, or may wake you from sleep. Many people ""shake out"" their hands to try to relieve their symptoms. The numb feeling may become constant over time. Weakness. You may experience weakness in the hand and drop objects. This may be due to the numbness in the hand or weakness of the thumb's pinching muscles, which are also controlled by the median nerve.",174,Carpal Tunnel Syndrome "Signs and symptoms of pheochromocytomas often include: High blood pressure Headache Heavy sweating Rapid heartbeat Tremors Pallor Shortness of breath Panic attack-type symptoms Less common signs or symptoms may include: Anxiety or sense of doom Blurry vision Constipation Weight loss Symptomatic spells The symptoms of pheochromocytoma may be constant, or they may occur, or get stronger, occasionally. These spells can happen because of activities or conditions, foods high in a substance that affects blood pressure (tyramine), and medications. Certain activities or conditions can make symptoms worse, such as: Certain activities or conditions Physical hard work Anxiety or stress Changes in body position, such as going from sitting or lying down to standing Labor and delivery Surgery and a drug that causes you to be in a sleep-like state during surgery (anesthesia) Foods high in tyramine, a substance that affects blood pressure, also can make symptoms worse. Tyramine is common in foods that are fermented, aged, pickled, cured, overripe or spoiled. These foods include: Foods high in tyramine, Some cheeses Some beers and wines Chocolate Dried or smoked meats Certain medications that can make symptoms worse include: Certain medications Monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil), tranylcypromine (Parnate) and isocarboxazid (Marplan) Stimulants, such as amphetamines or cocaine When to see a doctor Although high blood pressure is a primary sign of a pheochromocytoma, most people who have high blood pressure don't have an adrenal tumor. Talk to your health care provider if any of these factors apply to you: Difficulty controlling high blood pressure with current treatment Spells of worsening high blood pressure A family history of pheochromocytoma A family history of a related genetic disorder: multiple endocrine neoplasia, type 2 (MEN 2), von Hippel-Lindau disease, hereditary paraganglioma syndromes or neurofibromatosis 1",753,Pheochromocytoma "Grand mal seizures have two stages: Tonic phase. Loss of consciousness occurs, and the muscles suddenly contract and cause the person to fall down. This phase tends to last about 10 to 20 seconds. Clonic phase. The muscles go into rhythmic contractions, alternately flexing and relaxing. Convulsions usually last one to two minutes or less. The following signs and symptoms occur in some but not all people with grand mal seizures: A scream. Some people may cry out at the beginning of a seizure. Loss of bowel and bladder control. This may happen during or following a seizure. Unresponsiveness after convulsions. Unconsciousness may persist for several minutes after the convulsion has ended. Confusion. A period of disorientation often follows a grand mal seizure. This is referred to as postictal confusion. Fatigue. Sleepiness is common after a grand mal seizure. Severe headache. Headaches may occur after a grand mal seizure.",425,Grand Mal Seizure "Plantar fasciitis typically causes a stabbing pain in the bottom of your foot near the heel. The pain is usually the worst with the first few steps after awakening, although it can also be triggered by long periods of standing or when you get up from sitting.",764,Plantar Fasciitis "related chest pain: Chest pain is often associated with heart disease. But many people with heart disease say they have a mild discomfort that they wouldn't really call pain. Chest discomfort due to a heart attack or another heart problem may feel like: Pressure, fullness, burning or tightness in the chest. Crushing or searing pain that spreads to the back, neck, jaw, shoulders, and one or both arms. Pain that lasts more than a few minutes, gets worse with activity, goes away and comes back, or varies in intensity. Shortness of breath. Cold sweats. Dizziness, lightheadedness or weakness. Racing heartbeats. Nausea or vomiting. Other types of chest pain It can be difficult to tell if chest pain is related to the heart or caused by something else. Usually, chest pain is less likely due to a heart problem if it happens with: A sour taste or a sensation of food reentering the mouth Trouble swallowing Pain that gets better or worse when you change body position Pain that gets worse when you breathe deeply or cough Tenderness when you push on your chest Pain that continues for many hours The classic symptoms of heartburn — a painful, burning sensation behind the breastbone — can be caused by problems with the heart or the stomach.",191,Chest Pain "Drug allergy symptoms may include: Skin rash Hives Itching Fever Swelling Shortness of breath Wheezing Runny nose Itchy, watery eyes Anaphylaxis Anaphylaxis is a rare, life-threatening reaction to a drug allergy that causes the widespread dysfunction of body systems. Symptoms of anaphylaxis include: Tightening of the airways and throat, causing trouble breathing Nausea or abdominal cramps Vomiting or diarrhea Dizziness or lightheadedness Weak, fast pulse Drop in blood pressure Seizure Loss of consciousness Other conditions resulting from drug allergy Less-common drug allergy reactions happen days or weeks after exposure to a drug and may persist for some time after you stop taking the drug. These conditions include: Serum sickness, which may cause fever, joint pain, rash, swelling and nausea Drug-induced anemia, a reduction in red blood cells, which can cause fatigue, irregular heartbeats, shortness of breath and other symptoms Drug rash with eosinophilia and systemic symptoms (DRESS), which results in rash, high white blood cell count, general swelling, swollen lymph nodes and recurrence of dormant hepatitis infection Inflammation in the kidneys, also called nephritis, which can cause fever, blood in the urine, general swelling, confusion and other symptoms",307,Drug Allergy Symptoms might include: Chest pain Fever,305,Dresslers Syndrome "Patellar tendinitis: Patellar tendinitis causes pain in the patellar tendon, which runs from the kneecap (patella) to the shinbone (tibia). Pain is the first symptom of patellar tendinitis, usually between your kneecap and where the tendon attaches to your shinbone (tibia). Initially, you may only feel pain in your knee as you begin physical activity or just after an intense workout. Over time, the pain worsens and starts to interfere with playing your sport. Eventually, the pain interferes with daily movements such as climbing stairs or rising from a chair.",722,Patellar Tendinitis "related signs and symptoms: Nearly everyone who has scleroderma experiences a hardening and tightening of the skin. The first parts of the body to be affected are usually the fingers, hands, feet and face. In some people, the skin thickening can also involve the forearms, upper arms, chest, abdomen, lower legs and thighs. Early symptoms may include swelling and itchiness. Affected skin can become lighter or darker in color and may look shiny because of the tightness. Some people also experience small red spots, called telangiectasia, on their hands and face. Calcium deposits can form under the skin, particularly at the fingertips, causing bumps that can be seen on X-rays. Raynaud's phenomenon Raynaud's phenomenon is common in scleroderma and occurs because of an inappropriate and exaggerated contraction of the small blood vessels in the fingers and toes in response to the cold or emotional distress. When this happens, the digits may turn white, blue or red, and feel painful or numb. Raynaud's phenomenon also can occur in people who don't have scleroderma. Digestive problems Scleroderma can affect any part of the digestive system, from the esophagus to the rectum. Depending on which parts of the digestive system are affected, signs and symptoms may include: Heartburn Difficulty swallowing Bloating Diarrhea Constipation Fecal incontinence Heart and lung problems When scleroderma affects the heart or lungs, it can cause shortness of breath, decreased exercise tolerance and dizziness. Scleroderma can cause scarring in the lung tissues that may result in increasing shortness of breath over time. There are medications that may help slow the progression of this lung damage. Scleroderma can also cause the blood pressure to increase in the circulation that goes between the heart and the lungs. This is called pulmonary hypertension. In addition to shortness of breath, pulmonary hypertension can also cause excess fluid in the legs, feet and sometimes around the heart. When scleroderma affects the heart, heartbeats can become irregular. Heart failure may also occur in some people.",885,Scleroderma Signs and symptoms of tonsil cancer include: Difficulty swallowing A sensation that something is caught in the back of your throat Swelling and pain in the neck Earache Jaw stiffness,994,Tonsil Cancer "a person may: Begin with a frightening scream or shout Sit up in bed and appear frightened Stare wide-eyed Sweat, breathe heavily, and have a racing pulse, flushed face and dilated pupils Kick and thrash Be hard to awaken, and be confused if awakened Be inconsolable Have no or little memory of the event the next morning Possibly, get out of bed and run around the house or have aggressive behavior if blocked or restrained When to see a doctor Occasional sleep terrors aren't usually a cause for concern. If your child has sleep terrors, you can simply mention them at a routine well-child exam. However, consult your doctor if sleep terrors: Become more frequent Routinely disrupt the sleep of the person with sleep terrors or other family members Lead to safety concerns or injury Result in daytime symptoms of excessive sleepiness or problems functioning Continue beyond the teen years or start in adulthood",913,Sleep Terrors "noninfected: Bartholin's cyst, you may not notice it. If the cyst grows, you might feel a lump or mass near your vaginal opening. Although a cyst is usually painless, it can be tender. A full-blown infection of a Bartholin's cyst can occur in a matter of days. If the cyst becomes infected, you may experience: A tender, painful lump near the vaginal opening Discomfort while walking or sitting Pain during intercourse Fever A Bartholin's cyst or abscess typically occurs on only one side of the vaginal opening.",100,Bartholin Cyst "They may include: Pain or burning sensation when urinating (dysuria) Difficulty urinating, such as dribbling or hesitant urination Frequent urination, particularly at night (nocturia) Urgent need to urinate Cloudy urine Blood in the urine Pain in the abdomen, groin or lower back Pain in the area between the scrotum and rectum (perineum) Pain or discomfort of the penis or testicles Painful ejaculation Fever, chills, muscle aches and other flu-like symptoms (with acute bacterial prostatitis)",816,Prostatitis "Duchenne type muscular dystrophy: This is the most common form. Although girls can be carriers and mildly affected, it's much more common in boys. Signs and symptoms, which typically appear in early childhood, might include: Frequent falls Difficulty rising from a lying or sitting position Trouble running and jumping Waddling gait Walking on the toes Large calf muscles Muscle pain and stiffness Learning disabilities Delayed growth Becker muscular dystrophy Signs and symptoms are similar to those of Duchenne muscular dystrophy, but tend to be milder and progress more slowly. Symptoms generally begin in the teens but might not occur until the mid-20s or later. Other types of muscular dystrophy Some types of muscular dystrophy are defined by a specific feature or by where in the body symptoms begin. Examples include: Myotonic. This is characterized by an inability to relax muscles following contractions. Facial and neck muscles are usually the first to be affected. People with this form typically have long, thin faces; drooping eyelids; and swanlike necks. Facioscapulohumeral (FSHD). Muscle weakness typically begins in the face, hip and shoulders. The shoulder blades might stick out like wings when arms are raised. Onset usually occurs in the teenage years but can begin in childhood or as late as age 50. Congenital. This type affects boys and girls and is apparent at birth or before age 2. Some forms progress slowly and cause only mild disability, while others progress rapidly and cause severe impairment. Limb-girdle. Hip and shoulder muscles are usually affected first. People with this type of muscular dystrophy might have difficulty lifting the front part of the foot and so might trip frequently. Onset usually begins in childhood or the teenage years.",658,Muscular Dystrophy "Sciatica pain can be almost anywhere along the nerve pathway. It's especially likely to follow a path from the low back to the buttock and the back of a thigh and calf. The pain can vary from a mild ache to a sharp, burning pain. Sometimes it can feel like a jolt or electric shock. It can be worse when coughing or sneezing or sitting a long time. Usually, sciatica affects only one side of the body. Some people also have numbness, tingling or muscle weakness in the leg or foot. One part of the leg can be in pain, while another part can feel numb.",884,Sciatica "Pinched nerve signs and symptoms include: Numbness or decreased sensation in the area supplied by the nerve Sharp, aching or burning pain, which may radiate outward Tingling, pins and needles sensations (paresthesia) Muscle weakness in the affected area Frequent feeling that a foot or hand has ""fallen asleep"" The problems related to a pinched nerve may be worse when you're sleeping.",755,Pinched Nerve "Signs and symptoms of a miscarriage might include: Vaginal spotting or bleeding Pain or cramping in your abdomen or lower back Fluid or tissue passing from your vagina If you have passed fetal tissue from your vagina, place it in a clean container and bring it to your health care provider's office or the hospital for analysis. Most women who have vaginal spotting or bleeding in the first trimester go on to have successful pregnancies.",794,Pregnancy Loss Miscarriage "angle glaucoma: No symptoms in early stages Gradually, patchy blind spots in your side vision. Side vision also is known as peripheral vision In later stages, difficulty seeing things in your central vision Acute angle-closure glaucoma Severe headache Severe eye pain Nausea or vomiting Blurred vision Halos or colored rings around lights Eye redness Normal-tension glaucoma No symptoms in early stages Gradually, blurred vision In later stages, loss of side vision Glaucoma in children A dull or cloudy eye (infants) Increased blinking (infants) Tears without crying (infants) Blurred vision Nearsightedness that gets worse Headache Pigmentary glaucoma Halos around lights Blurred vision with exercise Gradual loss of side vision",418,Glaucoma "Signs and symptoms may include: Growing lump or area of swelling If it grows very large, there may be pain, tingling and numbness If it occurs in an arm or leg, there may be swelling in the hand or foot of an affected limb If it occurs in the abdomen, there may be pain, loss of appetite and constipation Fever Weight loss",1031,Undifferentiated Pleomorphic Sarcoma "you might feel: Pain only at sexual entry (penetration) Pain with every penetration, including putting in a tampon Deep pain during thrusting Burning pain or aching pain Throbbing pain, lasting hours after intercourse",712,Painful Intercourse "Signs and symptoms of vulvar cancer may include: Itching that doesn't go away Pain and tenderness Bleeding that isn't from menstruation Skin changes, such as color changes or thickening A lump, wartlike bumps or an open sore (ulcer)",1063,Vulvar Cancer "Symptoms of dermatographia may include: Raised, inflamed lines where you scratched. Welts from friction. Swelling. Itching. The symptoms may occur within a few minutes of the skin being rubbed or scratched. They tend to go away within 30 minutes. Rarely, the skin symptoms develop more slowly and lasts several hours to days. The condition itself can last for months or years.",280,Dermatographia "Symptoms of: Zollinger-Ellison syndrome may include: Stomach pain. Diarrhea. Burning, aching or discomfort in your upper abdomen. Acid reflux and heartburn. Burping. Nausea and vomiting. Bleeding in your digestive tract. Losing weight without trying. Loss of appetite.",1081,Zollinger Ellison Syndrome "include: Difficulty moving on one or both sides of the body, which gets worse over time Poor coordination Trouble with balance Stiffness Abnormal postures of the hands or feet, such as a hand forming a clenched fist Muscle jerks Difficulty swallowing Abnormal eye movements Trouble with thinking and language skills Speech problems, such as slow and halting speech Difficulty swallowing Corticobasal degeneration progresses over six to eight years. Eventually, people with corticobasal degeneration lose the ability to walk.",250,Corticobasal Degeneration "The primary symptoms of fibromyalgia include: Widespread pain. The pain associated with fibromyalgia often is described as a constant dull ache that has lasted for at least three months. To be considered widespread, the pain must occur on both sides of your body and above and below your waist. Fatigue. People with fibromyalgia often awaken tired, even though they report sleeping for long periods of time. Sleep is often disrupted by pain, and many patients with fibromyalgia have other sleep disorders, such as restless legs syndrome and sleep apnea. Cognitive difficulties. A symptom commonly referred to as ""fibro fog"" impairs the ability to focus, pay attention and concentrate on mental tasks. Fibromyalgia often co-exists with other conditions, such as: Irritable bowel syndrome Chronic fatigue syndrome Migraine and other types of headaches Interstitial cystitis or painful bladder syndrome Temporomandibular joint disorders Anxiety Depression Postural tachycardia syndrome",380,Fibromyalgia "and may include: Neck pain and stiffness Worsening of pain with neck movement Loss of range of motion in the neck Headaches, most often starting at the base of the skull Tenderness or pain in the shoulder, upper back or arms Tingling or numbness in the arms Fatigue Dizziness Some people also have: Blurred vision Ringing in the ears (tinnitus) Sleep disturbances Irritability Difficulty concentrating Memory problems Depression",1068,Whiplash "Skin: The easiest form of albinism to see results in white hair and very light-colored skin compared with siblings or other blood relatives. But skin coloring, also called pigmentation, and hair color can range from white to brown. People of African descent who have albinism may have skin that is light brown or red brown and have freckles. For some people, skin color may be nearly the same as that of parents or siblings without albinism. With exposure to the sun, some people may develop: Freckles. Moles, with or without color, which are sometimes pink. Large freckle-like spots, called solar lentigines (len-TIJ-ih-neez). Sunburn and no ability to tan. For some people with albinism, skin coloring never changes. For others, melanin production may begin or increase during childhood and the teen years, resulting in slight changes in color. Hair Hair color can range from very white to brown. People of African or Asian descent who have albinism may have hair color that's yellow, red or brown. Hair color also may darken by early adulthood. Or hair may stain from contact with minerals in water and the environment, making hair appear darker with age. Eye color Eyelashes and eyebrows are often pale. Eye color can range from very light blue to brown and may change with age. With albinism, the colored parts of the eyes, called the irises, usually don't have enough pigment. This allows light to shine through the irises and makes the eyes extremely sensitive to bright light. Because of this, very light-colored eyes may appear red in some lighting. Vision Vision problems are a key feature of all types of albinism. Eye problems may include: Rapid, back-and-forth movement of the eyes that can't be controlled, called nystagmus. An uncommon head position or head posture, such as tilting the head to try to reduce eye movements and see better. Eyes that can't look at the same direction at the same time or they appear to be crossed, a condition called strabismus. Problems seeing near objects or far objects, called farsightedness or nearsightedness. Extreme sensitivity to light, called photophobia. A difference in the curve of the front surface of the eye or the lens inside the eye, called astigmatism, which causes blurred vision. Differences in the development of the thin layer of tissue on the inside back wall of the eye, called the retina. This difference results in reduced vision. Nerve signals from the retina to the brain that don't follow the usual nerve pathways in the eye. This is called misrouting of the optic nerve. Poor depth perception, which means not being able to see things in three dimensions and judge how far away an object is. Legal blindness — vision less than 20/200 — or complete blindness.",29,Albinism "Signs and symptoms of esophageal cancer include: Difficulty swallowing (dysphagia) Weight loss without trying Chest pain, pressure or burning Worsening indigestion or heartburn Coughing or hoarseness Early esophageal cancer typically causes no signs or symptoms.",352,Esophageal Cancer "Symptoms of a broken collarbone include: Pain that increases when moving the shoulder. Swelling, tenderness or bruising. Skin over the break might look like a tent when gently pinched. A bump on or near the shoulder. A grinding or crackling sound when moving the shoulder. Stiffness or not being able to move the shoulder. Newborns often will not move their arm for days after breaking the collarbone during birth and will cry if someone moves the arm.",140,Broken Collarbone "Signs and symptoms of chemo brain may include the following: Being unusually disorganized Confusion Difficulty concentrating Difficulty finding the right word Difficulty learning new skills Difficulty multitasking Feeling of mental fogginess Short attention span Short-term memory problems Taking longer than usual to complete routine tasks Trouble with verbal memory, such as remembering a conversation Trouble with visual memory, such as recalling an image or list of words",190,Chemo Brain "CCMs: Generally, signs and symptoms of CCMs may include: CCMs Seizures Severe headaches Weakness in the arms or legs Numbness Difficulty speaking Problems with memory and attention Problems with balance and walking Vision changes, such as double vision Neurological issues can progressively worsen over time with recurrent bleeding. Repeat bleeding can happen soon after an initial bleed or much later. In other cases, a repeat bleed may never occur.",177,Cavernous Malformations "Common signs and symptoms of tonsillitis include: Red, swollen tonsils White or yellow coating or patches on the tonsils Sore throat Difficult or painful swallowing Fever Enlarged, tender glands (lymph nodes) in the neck A scratchy, muffled or throaty voice Bad breath Stomachache Neck pain or stiff neck Headache In young children who are unable to describe how they feel, signs of tonsillitis may include: Drooling due to difficult or painful swallowing Refusal to eat Unusual fussiness",995,Tonsillitis "including: Fever. Swollen lymph nodes that may last for weeks. Headache. Muscle aches. Skin rash. Symptoms of eye disease The toxoplasma parasites may infect tissues of the inner eye. This can occur in people with healthy immune systems. But the disease is more serious in people with weakened immunity. An infection in the eye is called ocular toxoplasmosis. Symptoms may include: Eye pain. Poor vision. Floaters, which are specks that seem to swim in your vision. Untreated eye disease can cause blindness. Effect on people with weakened immune systems People with weakened immune systems are likely to have more-serious disease from toxoplasmosis. A toxoplasmosis infection from earlier in life may become active again. People at risk include those living with HIV/AIDS, people receiving cancer treatment and people with a transplanted organ. In addition to serious eye disease, toxoplasmosis can cause severe lung or brain disease for a person with weakened immunity. Rarely, the infection can show up in other tissues throughout the body. Lung infection may cause: Breathing problems. Fever. Cough. Toxoplasmosis may cause inflammation of the brain, also called encephalitis. Symptoms may include: Confusion. Poor coordination. Muscle weakness. Seizures. Changes in alertness. Effect on fetus or infant Toxoplasmosis can pass from the mother to the fetus during a pregnancy. This is called congenital toxoplasmosis. Infection during the first trimester often causes more-severe disease. It also may result in miscarriage. For some babies with toxoplasmosis, serious disease may be present at birth or appear early in infancy. Medical problems may include: Too much fluid in or around the brain, also called hydrocephalus. Severe eye infection. Irregularities in brain tissues. An enlarged liver or spleen. Symptoms of severe disease vary. They may include: Problems with mental or motor skills. Blindness or other vision problems. Hearing problems. Heart disorders. Yellowing of the skin and whites of the eyes, also called jaundice. Rash. Most babies with toxoplasmosis do not show symptoms. But problems may show up later in childhood or teenage years. These include: Return of eye infections. Problems with motor skill development. Problems with thinking and learning. Hearing loss. Slowed growth. Early puberty.",1002,Toxoplasmosis "There are three forms of: Tay-Sachs disease: infantile, juvenile and late onset/adult. Infantile form In the most common and severe form, called infantile form, an infant typically begins showing signs and symptoms by about 3 to 6 months of age. Survival is usually only a few years. Signs and symptoms can include: Exaggerated startle response when the baby hears loud noises ""Cherry-red"" spots in the eyes Loss of motor skills, including turning over, crawling and sitting up Muscle weakness, progressing to paralysis Movement problems Seizures Vision loss and blindness Hearing loss and deafness Problems swallowing Loss of mental functions and a lack of response to surroundings Growth in head size (progressive macrocephaly) Juvenile form The juvenile form of Tay-Sachs disease is less common. Signs and symptoms vary in severity and begin in childhood. Survival is typically into the teen years. Signs and symptoms can include: Behavior problems Gradual loss of skills and movement control Frequent respiratory infections Slow loss of vision and speech Decline in mental function and responsiveness Seizures Last onset/adult form This is a rare and less severe form with signs and symptoms beginning in late childhood to adulthood. Severity of symptoms varies greatly, and this form does not always impact life expectancy. Signs and symptoms progress slowly and can include: Muscle weakness Clumsiness and loss of coordination Tremors and muscle spasms Loss of the ability to walk Problems speaking and swallowing Psychiatric disorders Sometimes loss of mental function",969,Tay Sachs Disease "Molar pregnancy: Molar pregnancy During a molar pregnancy, the placenta doesn't form typically. It can look like a mass of cysts. The fetus either doesn't form or doesn't form regularly and can't survive. A molar pregnancy may seem like a regular pregnancy at first. But most molar pregnancies cause symptoms that can include: Dark brown to bright red bleeding from the vagina during the first three months Severe nausea and vomiting Sometimes grapelike cysts that pass from the vagina Pelvic pressure or pain Because of improved ways of detecting a molar pregnancy, most are found in the first trimester. If it is not found in the first three months, symptoms of a molar pregnancy might include: A uterus growing quickly and being too large early in the pregnancy Preeclampsia a condition that causes high blood pressure and protein in the urine before 20 weeks of pregnancy Ovarian cysts Overactive thyroid, also known as hyperthyroidism",641,Molar Pregnancy Atypical hyperplasia usually doesn't cause any specific symptoms.,86,Atypical Hyperplasia "Physical signs and symptoms of a concussion may include: Headache Ringing in the ears Nausea Vomiting Fatigue or drowsiness Blurry vision Other signs and symptoms of a concussion include: Confusion or feeling as if in a fog Amnesia surrounding the traumatic event Dizziness or ""seeing stars"" A witness may observe these signs and symptoms in the concussed person: Temporary loss of consciousness (though this doesn't always occur) Slurred speech Delayed response to questions Dazed appearance Forgetfulness, such as repeatedly asking the same question You may have some symptoms of concussions immediately, and some can occur for days after the injury, such as: Concentration and memory complaints Irritability and other personality changes Sensitivity to light and noise Sleep disturbances Psychological adjustment problems and depression Disorders of taste and smell Symptoms in children Head trauma is very common in young children. But concussions can be difficult to recognize in infants and toddlers because they can't describe how they feel. Concussion clues may include: Dazed appearance Listlessness and tiring easily Irritability and crankiness Loss of balance and unsteady walking Excessive crying Change in eating or sleeping patterns Lack of interest in favorite toys Vomiting Seizures",239,Concussion "Signs and symptoms of bruxism may include: Teeth grinding or clenching, which may be loud enough to wake up your sleep partner Teeth that are flattened, fractured, chipped or loose Worn tooth enamel, exposing deeper layers of your tooth Increased tooth pain or sensitivity Tired or tight jaw muscles, or a locked jaw that won't open or close completely Jaw, neck or face pain or soreness Pain that feels like an earache, though it's actually not a problem with your ear Dull headache starting in the temples Damage from chewing on the inside of your cheek Sleep disruption When to see a doctor See your dentist or doctor if you have any of the symptoms listed above or have other concerns about your teeth or jaw. If you notice that your child is grinding his or her teeth — or has other signs or symptoms of bruxism — be sure to mention it at your child's next dental appointment.",154,Bruxism "The signs and symptoms that give scarlet fever its name include: Red rash. The rash looks like a sunburn and feels like sandpaper. It typically begins on the face or neck and spreads to the trunk, arms and legs. Pushing on the reddened skin makes it turn pale. Red lines. The folds of skin around the groin, armpits, elbows, knees and neck usually become a deeper red than the other areas with the rash. Flushed face. The face may appear flushed with a pale ring around the mouth. Strawberry tongue. The tongue generally looks red and bumpy, and it's often covered with a white coating early in the disease. Signs and symptoms of scarlet fever also include: Fever of 100.4 F (38.0 C) or higher, often with chills Very sore and red throat, sometimes with white or yellowish patches Difficulty swallowing Enlarged glands in the neck (lymph nodes) that are tender to the touch Nausea or vomiting Belly (abdominal) pain Headache and body aches The rash and the redness in the face and tongue usually last about a week. After these signs and symptoms have gone away, the skin affected by the rash often peels.",879,Scarlet Fever "They can include: Severe muscle rigidity or spasms Rapid, shallow breathing and problems with low oxygen and high carbon dioxide Rapid heart rate Irregular heart rhythm Dangerously high body temperature Excessive sweating Patchy, irregular skin color (mottled skin) In rare cases, people at risk of malignant hyperthermia have shown signs of a reaction after intense physical activity during excessive heat or humidity, during a viral illness, or when taking statin medication used to lower cholesterol. If you're at risk of malignant hyperthermia and you don't have a serious reaction during your first exposure to certain anesthesia drugs, you're still at risk if you receive these drugs in the future. Other anesthesia drugs that don't trigger a reaction can be used instead.",600,Malignant Hyperthermia "Other signs and symptoms of mitral valve regurgitation include: Sound of blood flow across the valve (heart murmur) Irregular heartbeat (arrhythmia) Shortness of breath (dyspnea), especially when lying down Sensation of a rapid, pounding or fluttering heartbeat (palpitations) Swollen feet or ankles (edema)",637,Mitral Valve Regurgitation "arms and legs: Itchiness A clear or scaly area inside the ring, perhaps with a scattering of bumps whose color ranges from red on white skin to reddish, purplish, brown or gray on black and brown skin Slightly raised, expanding rings A round, flat patch of itchy skin Overlapping rings",861,Ringworm Body "It is: Round with distinct, smooth borders Easily moved Firm or rubbery A fibroadenoma often grows slowly. The average size is about 1 inch (2.5 centimeters). A fibroadenoma can get bigger over time. It may be tender or cause soreness a few days before your period. A large fibroadenoma may hurt when you touch it. But most often, this type of breast lump causes no pain. You can have a single fibroadenoma or more than one fibroadenoma. They can occur in one or both breasts. Some fibroadenomas shrink over time. Most fibroadenomas in adolescents shrink over many months to a few years. They then disappear. Fibroadenomas may also change shape over time. Fibroadenomas may get bigger during pregnancy. They might shrink after menopause.",377,Fibroadenoma "Signs and symptoms you may notice include: Problems with sexual function — for example, difficulty with ejaculation or small volumes of fluid ejaculated, reduced sexual desire, or difficulty maintaining an erection (erectile dysfunction) Pain, swelling or a lump in the testicle area Recurrent respiratory infections Inability to smell Abnormal breast growth (gynecomastia) Decreased facial or body hair or other signs of a chromosomal or hormonal abnormality A lower than normal sperm count (fewer than 15 million sperm per milliliter of semen or a total sperm count of less than 39 million per ejaculate)",599,Male Infertility "SCAD: Chest pain A rapid heartbeat or fluttery feeling in the chest Pain in the arms, shoulders, back or jaw Shortness of breath Sweating Unusual, extreme tiredness Nausea Dizziness",934,Spontaneous Coronary Artery Dissection "you may experience some of the following signs and symptoms: Immediate, throbbing pain Swelling Bruising Tenderness Deformity Difficulty or pain with walking or bearing weight",138,Broken Ankle "symptoms may include: Blurred or fading vision Dizziness or lightheadedness Fainting Fatigue Trouble concentrating Nausea For some people, low blood pressure may be a sign of an underlying health condition, especially when it drops suddenly or occurs with symptoms. A sudden fall in blood pressure can be dangerous. A change of just 20 mm Hg — a drop from 110 mm Hg systolic to 90 mm Hg systolic, for example — can cause dizziness and fainting. And big drops, such as those caused by uncontrolled bleeding, severe infections or allergic reactions, can be life-threatening. mm Hg mm Hg mm Hg Extreme low blood pressure can lead to a condition known as shock. Symptoms of shock include: Confusion, especially in older people Cold, clammy skin Decrease in skin coloration (pallor) Rapid, shallow breathing Weak and rapid pulse",586,Low Blood Pressure "Signs and symptoms of hypospadias may include: Opening of the urethra at a location other than the tip of the penis Downward curve of the penis (chordee) Hooded appearance of the penis because only the top half of the penis is covered by foreskin Abnormal spraying during urination When to see a doctor When to see a doctor Most infants with hypospadias are diagnosed soon after birth while still in the hospital. However, slight displacement of the urethral opening may be subtle and more difficult to identify. Talk to your doctor if you have concerns about the appearance of your child's penis or if there are problems with urination.",509,Hypospadias "Many people with: Brugada syndrome don't know they have it. Signs and symptoms that may be associated with Brugada syndrome include: Dizziness Fainting Gasping and labored breathing, particularly at night Irregular heartbeats or palpitations Extremely fast and chaotic heartbeat Seizures A major sign of Brugada syndrome is an irregular result on an electrocardiogram (ECG), a test that measures the electrical activity of the heart.",153,Brugada Syndrome "The most common symptom of a rectovaginal fistula is passing gas or stool from the vagina. Depending on the fistula's size and location, you may have only minor symptoms. Or you may have significant problems with stool and gas leakage and keeping the area clean.",844,Rectovaginal Fistula "Widow spider bites: Signs and symptoms of a widow spider bite can include: Redness, pain and swelling. You might have pain and swelling around the bite, which can spread into your abdomen, back or chest. Cramping. You might have severe abdominal rigidity or cramping, which is sometimes mistaken for appendicitis or a ruptured appendix. Nausea, vomiting, tremors or sweating. You might experience nausea, vomiting, tremors or sweating alone or in combination. Symptoms can last 1 to 3 days. Recluse spider bites Signs and symptoms of a recluse spider bite can include: Increasing pain over the first eight hours after the bite Fever, chills and body aches A bite wound with a pale center that turns dark blue or purple with a red ring around it A bite wound that grows into an open sore (ulcer) with the skin around it dying",927,Spider Bites "Skin anatomy: Skin anatomy Your skin has three layers that house your sweat and oil glands, hair follicles, melanocytes, and blood vessels. Skin anatomy Your skin has three layers that house your sweat and oil glands, hair follicles, melanocytes, and blood vessels. Your skin has three layers that house your sweat and oil glands, hair follicles, melanocytes, and blood vessels. Third-degree burn Third-degree burns extend into the fat layer that lies beneath the dermis. The skin may appear stiff, waxy white, leathery or tan. These types of burns usually require skin grafts for wound closure. Radiation burn Radiation burns can be caused by X-rays or radiation therapy to treat cancer. Burn symptoms vary depending on how deep the skin damage is. It can take a day or two for the signs and symptoms of a severe burn to develop. 1st-degree burn. This minor burn affects only the outer layer of the skin (epidermis). It may cause redness and pain. 2nd-degree burn. This type of burn affects both the epidermis and the second layer of skin (dermis). It may cause swelling and red, white or splotchy skin. Blisters may develop, and pain can be severe. Deep second-degree burns can cause scarring. 3rd-degree burn. This burn reaches to the fat layer beneath the skin. Burned areas may be black, brown or white. The skin may look leathery. Third-degree burns can destroy nerves, causing numbness.",161,Burns "Bone marrow: Bone marrow is a red, spongy material inside your bones that produces blood cells. Aplastic anemia can have no symptoms. When present, signs and symptoms can include: Fatigue Shortness of breath Rapid or irregular heart rate Pale skin Frequent or prolonged infections Unexplained or easy bruising Nosebleeds and bleeding gums Prolonged bleeding from cuts Skin rash Dizziness Headache Fever Aplastic anemia can be short-lived, or it can become chronic. It can be severe and even fatal.",67,Aplastic Anemia "loss of kidney function can cause: Nausea Vomiting Loss of appetite Fatigue and weakness Sleep problems Urinating more or less Decreased mental sharpness Muscle cramps Swelling of feet and ankles Dry, itchy skin High blood pressure (hypertension) that's difficult to control Shortness of breath, if fluid builds up in the lungs Chest pain, if fluid builds up around the lining of the heart Signs and symptoms of kidney disease are often nonspecific. This means they can also be caused by other illnesses. Because your kidneys are able to make up for lost function, you might not develop signs and symptoms until irreversible damage has occurred.",214,Chronic Kidney Disease "Signs and symptoms of: Prader-Willi syndrome can vary among individuals. Symptoms may slowly change over time from childhood to adulthood. Infants Signs and symptoms that may be present from birth include: Poor muscle tone. A primary sign during infancy is poor muscle tone (hypotonia). Babies may rest with their elbows and knees loosely extended instead of fixed, and they may feel floppy or like rag dolls when they're held. Distinct facial features. Children may be born with almond-shaped eyes, a narrowing of the head at the temples, a turned-down mouth and a thin upper lip. Poor sucking reflex. Infants may have a poor sucking reflex due to decreased muscle tone. Poor sucking makes feeding difficult and can result in failure to thrive. Generally poor responsiveness. A baby may seem unusually tired, respond poorly to stimulation, have a hard time waking up or have a weak cry. Underdeveloped genitals. Males may have a small penis and scrotum. The testicles may be small or not descended from the abdomen into the scrotum (cryptorchidism). In females, the clitoris and labia may be small. Early childhood to adulthood Other features of Prader-Willi syndrome appear during early childhood and remain throughout life, requiring careful management. These features may include: Food craving and weight gain. A classic sign of Prader-Willi syndrome is a constant craving for food, resulting in rapid weight gain, starting around age 2 years. Constant hunger leads to eating often and consuming large portions. Unusual food-seeking behaviors, such as hoarding food, or eating frozen food or even garbage, may develop. Underdeveloped sex organs. A condition called hypogonadism occurs when sex organs (testes in men and ovaries in women) produce little or no sex hormones. This results in underdeveloped sex organs, incomplete or delayed puberty, and in nearly all cases, infertility. Without treatment, women may not start menstruating until their 30s or may never menstruate, and men may not have much facial hair and their voices may never fully deepen. Poor growth and physical development. Underproduction of growth hormone can result in short adult height, low muscle mass and high body fat. Other endocrine problems may include underproduction of thyroid hormone (hypothyroidism) or central adrenal insufficiency, which prevents the body from responding appropriately during stress or infections. Cognitive impairment. Mild to moderate intellectual disability, such as issues with thinking, reasoning and problem-solving, is a common feature of the disorder. Even those without significant intellectual disability have some learning disabilities. Delayed motor development. Toddlers with Prader-Willi syndrome often reach milestones in physical movement — for example, sitting up or walking — later than other children do. Speech problems. Speech is often delayed. Poor articulation of words may be an ongoing problem into adulthood. Behavioral problems. Children and adults may at times be stubborn, angry, controlling or manipulative. They may throw temper tantrums, especially when denied food, and may not tolerate changes in routine. They may also develop obsessive-compulsive or repetitive behaviors, or both. Other mental health disorders, such as anxiety and skin picking, may develop. Sleep disorders. Children and adults with Prader-Willi syndrome may have sleep disorders, including disruptions of the normal sleep cycle and a condition in which breathing pauses during sleep (sleep apnea). These disorders can result in excessive daytime sleepiness and worsen behavior problems. Other signs and symptoms. These may include small hands and feet, curvature of the spine (scoliosis), hip problems, reduced saliva flow, nearsightedness and other vision problems, problems regulating body temperature, a high pain tolerance, or a lack of pigment (hypopigmentation) causing hair, eyes and skin to be pale.",790,Prader Willi Syndrome A growing lump of tissue under your skin: Pain Swelling Weakness of the affected limb Liposarcoma that forms in the abdomen can cause: Abdominal pain Abdominal swelling Feeling full sooner when eating Constipation Blood in stool,579,Liposarcoma "Schizotypal personality disorder typically includes five or more of these signs and symptoms: Being a loner and lacking close friends outside of the immediate family Flat emotions or limited or inappropriate emotional responses Persistent and excessive social anxiety Incorrect interpretation of events, such as a feeling that something that is actually harmless or inoffensive has a direct personal meaning Peculiar, eccentric or unusual thinking, beliefs or mannerisms Suspicious or paranoid thoughts and constant doubts about the loyalty of others Belief in special powers, such as mental telepathy or superstitions Unusual perceptions, such as sensing an absent person's presence or having illusions Dressing in peculiar ways, such as appearing unkempt or wearing oddly matched clothes Peculiar style of speech, such as vague or unusual patterns of speaking, or rambling oddly during conversations Signs and symptoms of schizotypal personality disorder, such as increased interest in solitary activities or a high level of social anxiety, may be seen in the teen years. The child may be an underperformer in school or appear socially out of step with peers, which may result in teasing or bullying. Schizotypal personality disorder vs. schizophrenia Schizotypal personality disorder can easily be confused with schizophrenia, a severe mental illness in which people lose contact with reality (psychosis). While people with schizotypal personality disorder may experience brief psychotic episodes with delusions or hallucinations, the episodes are not as frequent, prolonged or intense as in schizophrenia. Another key distinction is that people with schizotypal personality disorder usually can be made aware of the difference between their distorted ideas and reality. Those with schizophrenia generally can't be swayed away from their delusions. Despite the differences, people with schizotypal personality disorder can benefit from treatments similar to those used for schizophrenia. Schizotypal personality disorder is sometimes considered to be on a spectrum with schizophrenia, with schizotypal personality disorder viewed as less severe.",883,Schizotypal Personality Disorder "Signs and symptoms of rickets can include: Delayed growth Delayed motor skills Pain in the spine, pelvis and legs Muscle weakness Because rickets softens the areas of growing tissue at the ends of a child's bones (growth plates), it can cause skeletal deformities such as: Bowed legs or knock knees Thickened wrists and ankles Breastbone projection When to see a doctor Talk to your doctor if your child develops bone pain, muscle weakness or obvious skeletal deformities.",860,Rickets "Female reproductive system: The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. Early vaginal cancer may not cause any signs and symptoms. As it progresses, vaginal cancer may cause signs and symptoms such as: Unusual vaginal bleeding, for example, after intercourse or after menopause Watery vaginal discharge A lump or mass in your vagina Painful urination Frequent urination Constipation Pelvic pain",1043,Vaginal Cancer Signs and symptoms of a hip fracture include: Inability to get up from a fall or to walk Severe pain in the hip or groin Inability to put weight on the leg on the side of the injured hip Bruising and swelling in and around the hip area Shorter leg on the side of the injured hip Outward turning of the leg on the side of the injured hip,479,Hip Fracture "Folliculitis: Superficial folliculitis can look like a pus-filled bump. Hot tub folliculitis Hot tub folliculitis causes round, itchy bumps that may later develop into small pus-filled blisters. The rash is likely to be worse in areas where your swimsuit holds water against the skin. Pseudofolliculitis barbae Razor bumps affect people with curly beards. The condition is also called pseudofolliculitis barbae. It develops when shaved hairs curve back into the skin, leading to inflammation. Carbuncle Carbuncle A carbuncle is a cluster of boils painful, pus-filled bumps that form a connected area of infection under the skin. Carbuncle A carbuncle is a cluster of boils painful, pus-filled bumps — that form a connected area of infection under the skin. Folliculitis signs and symptoms include: Clusters of small bumps or pimples around hair follicles Pus-filled blisters that break open and crust over Itchy, burning skin Painful, tender skin An inflamed bump",384,Folliculitis such as: The sudden appearance of many floaters — tiny specks that seem to drift through your field of vision Flashes of light in one or both eyes (photopsia) Blurred vision Gradually reduced side (peripheral) vision A curtain-like shadow over your field of vision,850,Retinal Detachment "Age spots on the hand: Age spots may grow in size and group together, giving the skin a speckled or mottled appearance. They're very common in areas that get repeated sun exposure, such as on the back of the hand.They're very common in areas that get repeated sun exposure, such as on the back of the hand. Age spots may affect people of all skin types, but they're more common in adults with light skin. Unlike freckles, which are common in children and fade with no sun exposure, age spots don't fade. Age spots: Are flat, oval areas of increased pigmentation Are usually tan to dark brown Occur on skin that has had the most sun exposure over the years, such as the backs of hands, tops of feet, face, shoulders and upper back Range from freckle size to about 1/2 inch (13 millimeters) across Can group together, making them more noticeable",25,Age Spots "re experiencing: Low sexual desire. This most common of female sexual dysfunctions involves a lack of sexual interest and willingness to be sexual. Sexual arousal disorder. Your desire for sex might be intact, but you have difficulty with arousal or are unable to become aroused or maintain arousal during sexual activity. Orgasmic disorder. You have persistent or recurrent difficulty in achieving orgasm after sufficient sexual arousal and ongoing stimulation. Sexual pain disorder. You have pain associated with sexual stimulation or vaginal contact.",373,Female Sexual Dysfunction "Molluscum contagiosum signs and symptoms include: Raised, round, skin-colored bumps Small bumps — typically under about 1/4 inch (smaller than 6 millimeters) in diameter Bumps with a small dent or dot at the top near the center Itchy, pink bumps Bumps on the face, trunk, arms or legs of children Bumps on the genitals, lower abdomen or inner thighs of adults if the infection was sexually transmitted",644,Molluscum Contagiosum "include: Fever Loss of appetite Headache Tiredness and a general feeling of being unwell (malaise) Once the chickenpox rash appears, it goes through three phases: Raised pink or red bumps (papules), which break out over several days Small fluid-filled blisters (vesicles), which form in about one day and then break and leak Crusts and scabs, which cover the broken blisters and take several more days to heal New bumps continue to appear for several days, so you may have all three stages of the rash — bumps, blisters and scabbed lesions — at the same time. You can spread the virus to other people for up to 48 hours before the rash appears, and the virus remains contagious until all broken blisters have crusted over. The disease is generally mild in healthy children. In severe cases, the rash can cover the entire body, and lesions may form in the throat, eyes, and mucous membranes of the urethra, anus and vagina.",194,Chickenpox "Signs and symptoms of acute myelogenous leukemia include: Fever Bone pain Lethargy and fatigue Shortness of breath Pale skin Frequent infections Easy bruising Unusual bleeding, such as frequent nosebleeds and bleeding from the gums",15,Acute Myelogenous Leukemia "Signs and symptoms of encopresis may include: Leakage of stool or liquid stool on underwear, which can be mistaken for diarrhea Constipation with dry, hard stool Passage of large stool that clogs or almost clogs the toilet Avoidance of bowel movements Long periods of time between bowel movements Lack of appetite Abdominal pain Problems with daytime wetting or bedwetting (enuresis) Repeated bladder infections, typically in girls",338,Encopresis "Signs and symptoms of sinus headaches may include: Pain, pressure and fullness in the cheeks, brow or forehead Worsening pain if you bend forward or lie down Stuffy nose Fatigue Achy feeling in the upper teeth Sinusitis or migraine? Migraines and headaches from sinusitis are easy to confuse because the signs and symptoms of the two types of headaches may overlap. Both migraine and sinusitis headache pain often get worse when you bend forward. Migraine can also be accompanied by various nasal signs and symptoms — including congestion, facial pressure and a clear, watery nasal discharge. These are due to involvement of the autonomic nervous system in a migraine attack. In fact, studies have shown that most people who see a health care provider for sinus headaches are found to have migraines instead. Sinusitis, however, usually isn't associated with nausea or vomiting or aggravated by noise or bright light — all common features of migraines. Sinusitis usually: Occurs after a viral upper respiratory infection or cold Includes thick, discolored nasal mucus Is associated with a decreased sense of smell Causes pain in one cheek or upper teeth Headaches due to sinus disease often last days or longer, and migraines most commonly last hours to a day or two.",908,Sinus Headaches "Signs and symptoms of small bowel cancer include: Abdominal pain Yellowing of the skin and the whites of the eyes (jaundice) Feeling unusually weak or tired Nausea Vomiting Losing weight without trying Blood in the stool, which might appear red or black Watery diarrhea Skin flushing Causes Doctors aren't certain what causes most small bowel cancers. In general, small bowel cancer begins when healthy cells in the small bowel develop changes (mutations) in their DNA. A cell's DNA contains a set of instructions that tell a cell what to do. Healthy cells grow and divide in an orderly way to keep your body functioning normally. But when a cell's DNA is damaged and becomes cancerous, cells continue to divide — even when new cells aren't needed. As these cells accumulate, they form a tumor. With time, the cancer cells can grow to invade and destroy normal tissue nearby. And cancerous cells can spread (metastasize) to other parts of the body. Risk factors Factors that may increase the risk of small bowel cancer include: Gene mutations passed through families. Some gene mutations that are inherited from your parents can increase your risk of small bowel cancer and other cancers. Examples include Lynch syndrome, familial adenomatous polyposis (FAP) and Peutz-Jeghers syndrome. Other bowel diseases. Other diseases and conditions that affect the intestines may increase the risk of small bowel cancer, including Crohn's disease, inflammatory bowel disease and celiac disease. Weakened immune system. If your body's germ-fighting immune system is weakened, you may have an increased risk of small bowel cancer. Examples include people with HIV infection and those who take anti-rejection medicine after an organ transplant. Complications Small bowel cancer can cause complications, including: An increased risk of other cancers. People who have small bowel cancer run a higher risk of having other types of cancers, including those that affect the colon, rectum, ovaries and the lining of the uterus (endometrium). Cancer that spreads to other parts of the body. Advanced small bowel cancer can spread (metastasize) to other parts of the body, most often the liver. Prevention It's not clear what may help to reduce the risk of small bowel cancer, since it's very uncommon. If you're interested in reducing your risk of cancer in general, it may help to: Eat a variety of fruits, vegetables and whole grains. Fruits, vegetables and whole grains contain vitamins, minerals, fiber and antioxidants, which may help reduce your risk of cancer and other diseases. Choose a variety of fruits and vegetables so that you get an array of vitamins and nutrients. Drink alcohol in moderation, if at all. If you choose to drink alcohol, limit the amount of alcohol you drink to no more than one drink a day for women of all ages and men older than age 65, and up to two drinks a day for men age 65 and younger. Stop smoking. Talk to your doctor about ways to quit that may work for you. Exercise most days of the week. Try to get at least 30 minutes of exercise on most days. If you've been inactive, start slowly and build up gradually to 30 minutes. Also, talk to your doctor before starting any exercise program. Maintain a healthy weight. If you are at a healthy weight, work to maintain your weight by combining a healthy diet with daily exercise. If you need to lose weight, ask your doctor about healthy ways to achieve your goal. Aim to lose weight slowly by increasing the amount of exercise you get and reducing the number of calories you eat. By Mayo Clinic Staff By Mayo Clinic Staff Small bowel cancer care at Mayo Clinic",915,Small Bowel Cancer "it may be an indication to see a doctor for further evaluation for OSA: Witnessed breathing pauses during sleep Excessive daytime sleepiness Difficulty concentrating Morning headaches Sore throat upon awakening Restless sleep Gasping or choking at night High blood pressure Chest pain at night Your snoring is so loud it's disrupting your partner's sleep In children, poor attention span, behavioral issues or poor performance in school OSA often is characterized by loud snoring followed by periods of silence when breathing stops or nearly stops. Eventually, this reduction or pause in breathing may signal you to wake up, and you may awaken with a loud snort or gasping sound. You may sleep lightly due to disrupted sleep. This pattern of breathing pauses may be repeated many times during the night. People with obstructive sleep apnea usually experience periods when breathing slows or stops at least five times during every hour of sleep.",919,Snoring "Nipple changes: Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Breast and nipple changes can be a sign of breast cancer. Signs and symptoms of breast cancer may include: A breast lump or thickening that feels different from the surrounding tissue Change in the size, shape or appearance of a breast Changes to the skin over the breast, such as dimpling A newly inverted nipple Peeling, scaling, crusting or flaking of the pigmented area of skin surrounding the nipple (areola) or breast skin Redness or pitting of the skin over your breast, like the skin of an orange",135,Breast Cancer "days after exposure and can include: Fever Chills Headache Muscle aches Dry cough Chest pain Tiredness Some people with histoplasmosis also get joint pain and a rash. People who have a lung disease, such as emphysema, can develop chronic histoplasmosis. Signs of chronic histoplasmosis can include weight loss and a bloody cough. Chronic histoplasmosis symptoms sometimes mimic those of tuberculosis. Severe histoplasmosis The most severe variety of histoplasmosis occurs mainly in infants and in people with weakened immune systems. Called disseminated histoplasmosis, it can affect nearly any part of your body, including your mouth, liver, central nervous system, skin and adrenal glands. If untreated, disseminated histoplasmosis is usually fatal.",482,Histoplasmosis "years include: Sudden high fever. Stiff neck. Severe headache. Nausea or vomiting. Confusion or trouble concentrating. Seizures. Sleepiness or trouble waking. Sensitivity to light. No appetite or thirst. Skin rash in some cases, such as in meningococcal meningitis. Signs in newborns Newborns and infants may show these signs: High fever. Constant crying. Being very sleepy or irritable. Trouble waking from sleep. Being inactive or sluggish. Not waking to eat. Poor feeding. Vomiting. A bulge in the soft spot on top of the baby's head. Stiffness in the body and neck. Infants with meningitis may be hard to comfort. They may even cry harder when held.",614,Meningitis "Signs and symptoms of a poison ivy rash include: Redness Itching Swelling Blisters Difficulty breathing, if you've inhaled the smoke from burning poison ivy Poison ivy rash often appears in a straight line because of the way the plant brushes against your skin. But if you develop a rash after touching a piece of clothing or pet fur that has urushiol on it, the rash may be more spread out. You can also transfer the oil to other parts of your body with your fingers. The reaction usually develops 12 to 48 hours after exposure and lasts two to three weeks. The severity of the rash depends on the amount of urushiol that gets on your skin.",769,Poison Ivy "The two main features of amnesia are: Trouble learning new information. Trouble remembering past events and previously familiar information. Most people with amnesia have problems with short-term memory, so they can't retain new information. Recent memories are most likely to be lost. More-remote or deeply ingrained memories may be spared. For example, people may recall experiences from childhood or know the names of past presidents. But they may not be able to name the current president, know the month or remember what they ate for breakfast. Isolated memory loss doesn't affect a person's intelligence, general knowledge, awareness or attention span. It also doesn't affect judgment, personality or identity. People with amnesia usually can understand written and spoken words and can learn skills such as bike riding or piano playing. They may understand they have a memory disorder. Amnesia isn't the same as dementia. Dementia often includes memory loss but also involves other problems with thinking that lead to a decline in daily functioning. These problems include having trouble with language, judgment and visual-spatial skills. Memory loss also is a common symptom of mild cognitive impairment. This disorder involves memory and other cognitive problems that aren't as severe as those experienced in dementia. Additional symptoms Depending on the cause of the amnesia, other symptoms may include: False memories that are either completely invented or are real memories misplaced in time. Confusion or disorientation.",41,Amnesia "they may include: Easy or excessive bruising Superficial bleeding into the skin that appears as pinpoint-sized reddish-purple spots (petechiae) that look like a rash, usually on the lower legs Bleeding from the gums or nose Blood in urine or stools Unusually heavy menstrual flow",512,Idiopathic Thrombocytopenic Purpura "look: Varied size, from very small to more than 1 inch (2.5 centimeters) across Varied number, ranging from a single growth to multiple growths Very small growths clustered around the eyes or elsewhere on the face, sometimes called flesh moles or dermatosis papulosa nigra, common on Black or brown skin Varied in color, ranging from light tan to brown or black Itchiness",892,Seborrheic Keratosis "Septic arthritis typically causes extreme discomfort and difficulty using the affected joint. The joint could be swollen, red and warm, and you might have a fever. If septic arthritis occurs in an artificial joint (prosthetic joint infection), signs and symptoms such as minor pain and swelling may develop months or years after knee replacement or hip replacement surgery. Also, a loosening of the joint may occur, which causes pain while moving the joint or while putting weight on the joint. Typically, the pain goes away when at rest. In extreme cases, the joint may become dislocated.",123,Bone And Joint Infections "Signs and symptoms may include: Diarrhea (often containing blood or mucus) Stomach pain or cramps Fever Nausea or vomiting Symptoms generally last for about five to seven days. In some cases, symptoms may last longer. Some people have no symptoms after they've been infected with shigella. However, their feces may still be contagious up to a few weeks.",902,Shigella "Signs and symptoms of gingivitis include: Swollen or puffy gums Dusky red or dark red gums Gums that bleed easily when you brush or floss Bad breath Receding gums Tender gums When to see a dentist If you notice any signs and symptoms of gingivitis, schedule an appointment with your dentist. The sooner you seek care, the better your chances of reversing damage from gingivitis and preventing its progression to periodontitis.",417,Gingivitis "Primary syphilis: Primary syphilis causes painless sores (chancres) on the genitals, rectum, tongue or lips. The disease can be present with the appearance of a single chancre (shown here on a penis) or many. Syphilis develops in stages, and symptoms vary with each stage. But the stages may overlap, and symptoms don't always occur in the same order. You may be infected with syphilis without noticing any symptoms for years. Primary syphilis The first sign of syphilis is a small sore, called a chancre (SHANG-kur). The sore appears at the spot where the bacteria entered your body. While most people infected with syphilis develop only one chancre, some people develop several of them. The chancre usually develops about three weeks after exposure. Many people who have syphilis don't notice the chancre because it's usually painless, and it may be hidden within the vagina or rectum. The chancre will heal on its own within three to six weeks. Secondary syphilis Within a few weeks of the original chancre healing, you may experience a rash that begins on your trunk but eventually covers your entire body even the palms of your hands and the soles of your feet. This rash is usually not itchy and may be accompanied by wartlike sores in your mouth or genital area. Some people also experience hair loss, muscle aches, a fever, a sore throat and swollen lymph nodes. These signs and symptoms may disappear within a few weeks or repeatedly come and go for as long as a year. Latent syphilis If you aren't treated for syphilis, the disease moves from the secondary stage to the hidden (latent) stage, when you have no symptoms. The latent stage can last for years. Signs and symptoms may never return, or the disease may progress to the third (tertiary) stage. Tertiary syphilis About 15% to 30% of people infected with syphilis who don't get treatment will develop complications known as tertiary syphilis. In the late stage, the disease may damage the brain, nerves, eyes, heart, blood vessels, liver, bones and joints. These problems may occur many years after the original, untreated infection. Neurosyphilis At any stage, syphilis can spread and, among other damage, cause damage to the brain and nervous system and the eye. Congenital syphilis Babies born to women who have syphilis can become infected through the placenta or during birth. Most newborns with congenital syphilis have no symptoms, although some experience a rash on the palms of their hands and the soles of their feet. Later signs and symptoms may include deafness, teeth deformities and saddle nose — where the bridge of the nose collapses. However, babies born with syphilis can also be born too early, may die in the womb before birth or can die after birth.",964,Syphilis "Possible signs and symptoms may include: Pain. A dull, aching pain or discomfort is more likely when standing or late in the day. Lying down often relieves pain. A mass in the scrotum. If a varicocele is large enough, a mass like a ""bag of worms"" may be visible above the testicle. A smaller varicocele may be too small to see but noticeable by touch. Differently sized testicles. The affected testicle may be noticeably smaller than the other testicle. Infertility. A varicocele may lead to difficulty fathering a child, but not all varicoceles cause infertility.",1046,Varicocele "you may notice these signs and symptoms all or most of the time: Dryness or a feeling of stickiness in your mouth Saliva that seems thick and stringy Bad breath Difficulty chewing, speaking and swallowing Dry or sore throat and hoarseness Dry or grooved tongue A changed sense of taste Problems wearing dentures In addition, dry mouth may result in lipstick sticking to the teeth.",311,Dry Mouth "These signs and symptoms may show up as: Delayed development of speech and language skills, as well as motor skills, such as sitting up and walking Learning disabilities, such as difficulty with reading, understanding or math Behavioral problems, such as attention-deficit/hyperactivity disorder (ADHD) or symptoms of autism spectrum disorder Psychological problems, such as anxiety and depression Problems with fine and gross motor skills, memory, judgment and information processing Sometimes females with triple X syndrome have these signs and symptoms: Vertical folds of skin that cover the inner corners of the eyes (epicanthal folds) Widely spaced eyes Curved pinky fingers Flat feet Breastbone with an inward bowed shape Weak muscle tone (hypotonia) Seizures Problems with the kidneys Ovaries that don't work properly at a young age (premature ovarian failure)",1017,Triple X Syndrome "Signs and symptoms may include: An intense fear of abandonment, even going to extreme measures to avoid real or imagined separation or rejection A pattern of unstable intense relationships, such as idealizing someone one moment and then suddenly believing the person doesn't care enough or is cruel Rapid changes in self-identity and self-image that include shifting goals and values, and seeing yourself as bad or as if you don't exist at all Periods of stress-related paranoia and loss of contact with reality, lasting from a few minutes to a few hours Impulsive and risky behavior, such as gambling, reckless driving, unsafe sex, spending sprees, binge eating or drug abuse, or sabotaging success by suddenly quitting a good job or ending a positive relationship Suicidal threats or behavior or self-injury, often in response to fear of separation or rejection Wide mood swings lasting from a few hours to a few days, which can include intense happiness, irritability, shame or anxiety Ongoing feelings of emptiness Inappropriate, intense anger, such as frequently losing your temper, being sarcastic or bitter, or having physical fights",127,Borderline Personality Disorder "Nipple changes: Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Paget's disease of the breast affects your nipple and usually the skin (areola) surrounding it. It's easy to mistake the signs and symptoms of Paget's disease of the breast for skin irritation (dermatitis) or another noncancerous (benign) skin condition. Possible signs and symptoms of Paget's disease of the breast include: Flaky or scaly skin on your nipple Crusty, oozing or hardened skin resembling eczema on the nipple, areola or both Itching Redness A tingling or burning sensation Straw-colored or bloody nipple discharge A flattened or turned-in (inverted) nipple A lump in the breast Thickening skin on the breast Signs and symptoms usually occur in one breast only. The disease typically starts in the nipple and may spread to the areola and other areas of the breast. The skin changes may come and go early on or respond to topical treatment, making it appear as if your skin is healing. On average, signs and symptoms occur for several months before a diagnosis is made.",711,Pagets Disease Of The Breast "Movement disorders: The movement disorders associated with Huntington's disease can include both involuntary movement problems and impairments in voluntary movements, such as: Involuntary jerking or writhing movements (chorea) Muscle problems, such as rigidity or muscle contracture (dystonia) Slow or unusual eye movements Impaired gait, posture and balance Difficulty with speech or swallowing Impairments in voluntary movements — rather than involuntary movements — may have a greater impact on a person's ability to work, perform daily activities, communicate and remain independent. Cognitive disorders Cognitive impairments often associated with Huntington's disease include: Difficulty organizing, prioritizing or focusing on tasks Lack of flexibility or the tendency to get stuck on a thought, behavior or action (perseveration) Lack of impulse control that can result in outbursts, acting without thinking and sexual promiscuity Lack of awareness of one's own behaviors and abilities Slowness in processing thoughts or ''finding'' words Difficulty in learning new information Psychiatric disorders The most common psychiatric disorder associated with Huntington's disease is depression. This isn't simply a reaction to receiving a diagnosis of Huntington's disease. Instead, depression appears to occur because of injury to the brain and subsequent changes in brain function. Signs and symptoms may include: Feelings of irritability, sadness or apathy Social withdrawal Insomnia Fatigue and loss of energy Frequent thoughts of death, dying or suicide Other common psychiatric disorders include: Obsessive-compulsive disorder, a condition marked by recurrent, intrusive thoughts and repetitive behaviors Mania, which can cause elevated mood, overactivity, impulsive behavior and inflated self-esteem Bipolar disorder, a condition with alternating episodes of depression and mania In addition to the above disorders, weight loss is common in people with Huntington's disease, especially as the disease progresses. Symptoms of juvenile Huntington's disease The start and progression of Huntington's disease in younger people may be slightly different from that in adults. Problems that often present early in the course of the disease include: Behavioral changes Difficulty paying attention Rapid, significant drop in overall school performance Behavioral problems Physical changes Contracted and rigid muscles that affect gait (especially in young children) Tremors or slight involuntary movements Frequent falls or clumsiness Seizures",490,Huntingtons Disease "In the lower back: Spinal stenosis in the lower back can cause pain or cramping in one or both legs. This happens when you stand for a long time or when you walk. Symptoms get better when you bend forward or sit. Some people also have back pain. In the neck Spinal stenosis in the neck can cause: Numbness Tingling or weakness in a hand, leg, foot or arm Problems with walking and balance Neck pain Problems with the bowel or bladder",933,Spinal Stenosis "Epidermolysis bullosa symptoms include: Fragile skin that blisters easily, especially on the palms and feet Nails that are thick or unformed Blisters inside the mouth and throat Scalp blistering and hair loss (scarring alopecia) Skin that looks thin Tiny pimple-like bumps (milia) Dental problems, such as tooth decay Difficulty swallowing Itchy, painful skin Usually epidermolysis bullosa blisters are noticed during infancy. But it's not uncommon for them to appear when a toddler first begins to walk or when an older child begins new activities that cause more friction on the soles of the feet.",348,Epidermolysis Bullosa "Signs and symptoms of pulmonary fibrosis may include: Shortness of breath (dyspnea) A dry cough Fatigue Unexplained weight loss Aching muscles and joints Widening and rounding of the tips of the fingers or toes (clubbing) The course of pulmonary fibrosis — and the severity of symptoms — can vary considerably from person to person. Some people become ill very quickly with severe disease. Others have moderate symptoms that worsen more slowly, over months or years. Some people may experience a rapid worsening of their symptoms (acute exacerbation), such as severe shortness of breath, that may last for several days to weeks. People who have acute exacerbations may be placed on a mechanical ventilator. Doctors may also prescribe antibiotics, corticosteroid medications or other medications to treat an acute exacerbation.",828,Pulmonary Fibrosis "some people with colon polyps may have: Change in bowel habits. Constipation or diarrhea that lasts longer than a week may mean the presence of a larger colon polyp or cancer. However, several other conditions also can cause changes in bowel habits. Change in stool color. Blood can show up as red streaks in your stool or make stool appear black. A change in color also may be caused by certain foods, medicines or dietary supplements. Iron deficiency anemia. Bleeding from polyps can happen slowly over time, without visible blood in your stool. Chronic bleeding may lead to iron deficiency anemia, which can make you feel tired and short of breath. Pain. A large colon polyp can block part of your bowel, leading to crampy abdominal pain. Rectal bleeding. This can be a sign of colon polyps or cancer or other conditions, such as hemorrhoids or minor tears of the anus.",232,Colon Polyps "Lichen sclerosus: Lichen sclerosus Lichen sclerosus is a skin condition characterized by discolored, blotchy patches of skin. Lichen sclerosus may affect skin on any part of your body but often involves the skin of the genital area. It's possible to have mild lichen sclerosus with no symptoms. When symptoms do occur, they usually affect the skin of the genital and anal areas. The back, shoulders, upper arms and breasts may also be affected. Symptoms may include: Smooth discolored skin patches Blotchy, wrinkled skin patches Itching Soreness or a burning feeling Easy bruising Fragile skin Changes in the tube for urine flow (urethra) Bleeding, blistering or open sores Painful sex",576,Lichen Sclerosus "Female genital warts: Female genital warts Genital warts are a common sexually transmitted infection. They can appear on the genitals, in the pubic area or in the anal canal. In women, genital warts can also grow inside the vagina. Male genital warts Genital warts are a common sexually transmitted infection. In women, genital warts can grow on the vulva, the walls of the vagina, the area between the external genitals and the anus, the anal canal, and the cervix. In men, they may occur on the tip or shaft of the penis, the scrotum, or the anus. Genital warts can also develop in the mouth or throat of a person who has had oral sexual contact with an infected person. The signs and symptoms of genital warts include: Small, flesh-colored, brown or pink swellings in your genital area A cauliflower-like shape caused by several warts close together Itching or discomfort in your genital area Bleeding with intercourse Genital warts can be so small and flat as to be invisible. Rarely, however, genital warts can multiply into large clusters in someone with a suppressed immune system.",410,Genital Warts "Inverted nipple: Inverted nipple Inverted nipple A nipple that's always been turned inward (inverted) usually isn't a medical concern. But a nipple that has recently turned inward should be checked by a doctor. Inverted nipple Inverted nipple Inverted nipple Inverted nipple A nipple that's always been turned inward (inverted) usually isn't a medical concern. Inverted nipple Inverted nipple A nipple that's always been turned inward (inverted) usually isn't a medical concern. Inverted nipple A nipple that's always been turned inward (inverted) usually isn't a medical concern. A nipple that's always been turned inward (inverted) usually isn't a medical concern. Mammary duct ectasia often doesn't cause any signs or symptoms, but some people experience: A dirty white, greenish or black nipple discharge from one or both nipples Tenderness in the nipple or surrounding breast tissue (areola) Redness of the nipple and areolar tissue A breast lump or thickening near the clogged duct A nipple that's turned inward (inverted) A bacterial infection called mastitis also may develop in the affected milk duct, causing breast tenderness, inflammation in the area around the nipple (areola) and fever. Signs and symptoms of mammary duct ectasia may improve on their own.",602,Mammary Duct Ectasia "Eyestrain symptoms include: Sore, tired, burning or itching eyes Watery or dry eyes Blurred or double vision Headache Sore neck, shoulders or back Increased sensitivity to light, called photophobia Difficulty concentrating Feeling that you cannot keep your eyes open",363,Eyestrain "Signs and symptoms include: Adults: Difficulty swallowing, also called dysphagia Food getting stuck in the esophagus after swallowing, also known as impaction Chest pain that is often centrally located and does not respond to antacids Backflow of undigested food, known as regurgitation Children: Difficulty feeding, in infants Difficulty eating, in children Vomiting Abdominal pain Difficulty swallowing, also called dysphagia Food getting stuck in the esophagus after swallowing, also known as impaction No response to GERD medication Failure to thrive, including poor growth, malnutrition and weight loss",346,Eosinophilic Esophagitis "Early warning signs and symptoms: Initial signs and symptoms of diabetic hypoglycemia include: Looking pale (pallor) Shakiness Dizziness or lightheadedness Sweating Hunger or nausea An irregular or fast heartbeat Difficulty concentrating Feeling weak and having no energy (fatigue) Irritability or anxiety Headache Tingling or numbness of the lips, tongue or cheek Nighttime signs and symptoms If diabetic hypoglycemia occurs when you're sleeping, signs and symptoms that may disturb your sleep include: Damp sheets or nightclothes due to perspiration Nightmares Tiredness, irritability or confusion upon waking Severe signs and symptoms If diabetic hypoglycemia isn't treated, signs and symptoms of hypoglycemia worsen and can include: Confusion, unusual behavior or both, such as the inability to complete routine tasks Loss of coordination Difficulty speaking or slurred speech Blurry or tunnel vision Inability to eat or drink Muscle weakness Drowsiness Severe hypoglycemia may cause: Convulsions or seizures Unconsciousness Death, rarely Symptoms can differ from person to person or from episode to episode. Some people don't have any noticeable symptoms. It's also possible you won't have any symptoms of hypoglycemia. It's important to monitor your blood sugar levels regularly and keep track of how you're feeling when your blood sugar is low.",288,Diabetic Hypoglycemia "Premature ejaculation can be classified as: Lifelong. Lifelong premature ejaculation occurs all or nearly all the time beginning with the first sexual encounter. Acquired. Acquired premature ejaculation develops after having previous sexual experiences without problems with ejaculation. Many people feel that they have symptoms of premature ejaculation, but the symptoms don't meet the criteria for a diagnosis. It's typical to experience early ejaculation at times.",797,Premature Ejaculation signs and symptoms may include: Lower abdominal pain Pain during urination Frequent urination Difficulty urinating or interrupted urine flow Blood in the urine Cloudy or unusually dark-colored urine,115,Bladder Stones neuroendocrine tumor signs and symptoms might include: Pain from a growing tumor A growing lump you can feel under the skin Feeling unusually tired Losing weight without trying Neuroendocrine tumors that produce excess hormones (functional tumors) might cause: Skin flushing Diarrhea Frequent urination Increased thirst Dizziness Shakiness Skin rash,678,Neuroendocrine Tumors "Signs and symptoms of complicated grief may include: Intense sorrow, pain and rumination over the loss of your loved one Focus on little else but your loved one's death Extreme focus on reminders of the loved one or excessive avoidance of reminders Intense and persistent longing or pining for the deceased Problems accepting the death Numbness or detachment Bitterness about your loss Feeling that life holds no meaning or purpose Lack of trust in others Inability to enjoy life or think back on positive experiences with your loved one Complicated grief also may be indicated if you continue to: Have trouble carrying out normal routines Isolate from others and withdraw from social activities Experience depression, deep sadness, guilt or self-blame Believe that you did something wrong or could have prevented the death Feel life isn't worth living without your loved one Wish you had died along with your loved one",238,Complicated Grief "Causes: In some people, the yips are a type of focal dystonia, a condition that causes involuntary muscle contractions during a specific task. It's most likely related to overuse of a certain set of muscles, similar to writer's cramp. Anxiety worsens the effect. Some athletes become so anxious and self-focused — overthinking to the point of distraction — that their ability to execute a skill, such as putting, is impaired. ""Choking"" is an extreme form of performance anxiety that may compromise a golfer's or any athlete's game. Risk factors The yips tend to be associated with: Older age More experience playing golf Tournament play By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment March 23, 2022 Print Print Share on: FacebookTwitter Facebook Twitter Show references Conidi F. Some unusual sports-related neurologic conditions. Continuum. 2014;20:1645. Dhungana S, et al. Yips and other movement disorders in golfers. Movement Disorders. 2013;28:576. Berstein CJ, et al. Behavioural interventions for people living with adult-onset primary dystonia: A systematic review. BMC Neurology. 2016;16:1. https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-016-0562-y. Accessed Feb. 2, 2018. Show references Conidi F. Conidi F. Related Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Related Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic YipsSymptoms & causesDiagnosis & treatment Yips Symptoms & causesDiagnosis & treatment",1079,Yips may include: Abdominal cramps or pain Bloating Nausea Vomiting Fever Blood in the stool Mucus in the stool Urgent need to have a bowel movement,294,Diarrhea "Seizure signs and symptoms may include: Temporary confusion A staring spell Stiff muscles Uncontrollable jerking movements of the arms and legs Loss of consciousness or awareness Psychological symptoms such as fear, anxiety or deja vu Symptoms vary depending on the type of seizure. In most cases, a person with epilepsy will tend to have the same type of seizure each time, so the symptoms will be similar from episode to episode. Doctors generally classify seizures as either focal or generalized, based on how and where the abnormal brain activity begins. Focal seizures When seizures appear to result from abnormal activity in just one area of your brain, they're called focal seizures. These seizures fall into two categories: Focal seizures without loss of consciousness. Once called simple partial seizures, these seizures don't cause a loss of consciousness. They may alter emotions or change the way things look, smell, feel, taste or sound. Some people experience deja vu. This type of seizure may also result in involuntary jerking of one body part, such as an arm or leg, and spontaneous sensory symptoms such as tingling, dizziness and flashing lights. Focal seizures with impaired awareness. Once called complex partial seizures, these seizures involve a change or loss of consciousness or awareness. This type of seizure may seem like being in a dream. During a focal seizure with impaired awareness, you may stare into space and not respond normally to your environment or perform repetitive movements, such as hand rubbing, chewing, swallowing or walking in circles. Symptoms of focal seizures may be confused with other neurological disorders, such as migraine, narcolepsy or mental illness. A thorough examination and testing are needed to distinguish epilepsy from other disorders. Generalized seizures Seizures that appear to involve all areas of the brain are called generalized seizures. Six types of generalized seizures exist. Absence seizures. Absence seizures, previously known as petit mal seizures, typically occur in children. They're characterized by staring into space with or without subtle body movements such as eye blinking or lip smacking and only last between 5-10 seconds. These seizures may occur in clusters, happening as often as 100 times per day, and cause a brief loss of awareness. Tonic seizures. Tonic seizures cause stiff muscles and may affect consciousness. These seizures usually affect muscles in your back, arms and legs and may cause you to fall to the ground. Atonic seizures. Atonic seizures, also known as drop seizures, cause a loss of muscle control. Since this most often affects the legs, it often causes you to suddenly collapse or fall down. Clonic seizures. Clonic seizures are associated with repeated or rhythmic, jerking muscle movements. These seizures usually affect the neck, face and arms. Myoclonic seizures. Myoclonic seizures usually appear as sudden brief jerks or twitches and usually affect the upper body, arms and legs. Tonic-clonic seizures. Tonic-clonic seizures, previously known as grand mal seizures, are the most dramatic type of epileptic seizure. They can cause an abrupt loss of consciousness and body stiffening, twitching and shaking. They sometimes cause loss of bladder control or biting your tongue.",350,Epilepsy "Disproportionate dwarfism: Most people with dwarfism have disorders that cause disproportionately short stature. Usually, this means that a person has an average-size trunk and very short limbs, but some people may have a very short trunk and shortened (but disproportionately large) limbs. In these disorders, the head is disproportionately large compared with the body. Almost all people with disproportionate dwarfism have normal intellectual capacities. Rare exceptions are usually the result of a secondary factor, such as excess fluid around the brain (hydrocephalus). The most common cause of dwarfism is a disorder called achondroplasia, which causes disproportionately short stature. This disorder usually results in the following: An average-size trunk Short arms and legs, with particularly short upper arms and upper legs Short fingers, often with a wide separation between the middle and ring fingers Limited mobility at the elbows A disproportionately large head, with a prominent forehead and a flattened bridge of the nose Progressive development of bowed legs Progressive development of swayed lower back An adult height around 4 feet (122 cm) Another cause of disproportionate dwarfism is a rare disorder called spondyloepiphyseal dysplasia congenita (SEDC). Signs may include: A very short trunk A short neck Shortened arms and legs Average-size hands and feet Broad, rounded chest Slightly flattened cheekbones Opening in the roof of the mouth (cleft palate) Hip deformities that result in thighbones turning inward A foot that's twisted or out of shape Instability of the neck bones Progressive hunching curvature of the upper spine Progressive development of swayed lower back Vision and hearing problems Arthritis and problems with joint movement Adult height ranging from 3 feet (91 cm) to just over 4 feet (122 cm) Proportionate dwarfism Proportionate dwarfism results from medical conditions present at birth or appearing in early childhood that limit overall growth and development. So the head, trunk and limbs are all small, but they're proportionate to each other. Because these disorders affect overall growth, many of them result in poor development of one or more body systems. Growth hormone deficiency is a relatively common cause of proportionate dwarfism. It occurs when the pituitary gland fails to produce an adequate supply of growth hormone, which is essential for normal childhood growth. Signs include: Height below the third percentile on standard pediatric growth charts Growth rate slower than expected for age Delayed or no sexual development during the teen years",319,Dwarfism "Signs and symptoms of generalized tetanus include: Painful muscle spasms and stiff, immovable muscles (muscle rigidity) in your jaw Tension of muscles around your lips, sometimes producing a persistent grin Painful spasms and rigidity in your neck muscles Difficulty swallowing Rigid abdominal muscles Progression of tetanus results in repeated painful, seizure-like spasms that last for several minutes (generalized spasms). Usually, the neck and back arch, the legs become rigid, the arms are drawn up to the body, and the fists are clenched. Muscle rigidity in the neck and abdomen may cause breathing difficulties. These severe spasms may be triggered by minor events that stimulate the senses — a loud sound, a physical touch, a draft or light. As the disease progresses, other signs and symptoms may include: High blood pressure Low blood pressure Rapid heart rate Fever Extreme sweating Localized tetanus This uncommon form of tetanus results in muscles spasms near the site of a wound. While it's usually a less severe form of disease, it can progress to generalized tetanus. Cephalic tetanus This rare form of tetanus results from a head wound. It results in weakened muscles in the face and spasms of the jaw muscles. It also can progress to generalized tetanus.",977,Tetanus "Seborrheic dermatitis signs and symptoms may include: Flaking skin (dandruff) on your scalp, hair, eyebrows, beard or mustache Patches of greasy skin covered with flaky white or yellow scales or crust on the scalp, face, sides of the nose, eyebrows, ears, eyelids, chest, armpits, groin area or under the breasts Rash that may look darker or lighter in people with brown or Black skin and redder in those with white skin Ring-shaped (annular) rash, for a type called petaloid seborrheic dermatitis Itchiness (pruritus) The signs and symptoms of seborrheic dermatitis tend to flare with stress, fatigue or a change of season.",891,Seborrheic Dermatitis "Esthesioneuroblastoma symptoms include: Losing the sense of smell Frequent nosebleeds Difficulty breathing through the nose As it grows, the cancer may cause eye pain, loss of vision, ear pain and headaches.",357,Esthesioneuroblastoma "Wrist pain may vary, depending on the cause. For example, osteoarthritis pain often is described as being similar to a dull toothache. Carpal tunnel syndrome usually causes a pins-and-needles feeling. This tingling sensation usually occurs in the thumb and index and middle fingers, especially at night. The precise location of wrist pain also provides clues to what's behind the symptoms.",1076,Wrist Pain "Most people have no symptoms associated with flatfeet. But some people with flatfeet experience foot pain, particularly in the heel or arch area. Pain may worsen with activity. Swelling may occur along the inside of the ankle.",381,Flatfeet "they may include: Shortness of breath, especially when sitting or standing Clubbing of the fingers, in which the fingertips spread out and become rounder than normal Broken blood vessels under the skin (spider angioma) Bluish tinge of the lips and skin (cyanosis) Causes Hepatopulmonary syndrome is caused when blood vessels in and around the lungs widen (dilate), which affects the amount of oxygen that moves from the lungs into the bloodstream. What causes this abnormality remains unclear, and it's unknown why some people with liver disease develop hepatopulmonary syndrome while others do not. By Mayo Clinic Staff By Mayo Clinic Staff Hepatopulmonary syndrome care at Mayo Clinic",469,Hepatopulmonary Syndrome SARS: Fever of 100.5 F (38 C) or higher Dry cough Shortness of breath,877,Sars minutes of eating: Abdominal pain or pressure relieved by regurgitation A feeling of fullness Bad breath Nausea Unintentional weight loss Rumination syndrome isn't usually associated with retching.,868,Rumination Syndrome "Anorexia nervosa: Anorexia (an-o-REK-see-uh) nervosa — often simply called anorexia — is a potentially life-threatening eating disorder characterized by an abnormally low body weight, intense fear of gaining weight, and a distorted perception of weight or shape. People with anorexia use extreme efforts to control their weight and shape, which often significantly interferes with their health and life activities. When you have anorexia, you excessively limit calories or use other methods to lose weight, such as excessive exercise, using laxatives or diet aids, or vomiting after eating. Efforts to reduce your weight, even when underweight, can cause severe health problems, sometimes to the point of deadly self-starvation. Bulimia nervosa Bulimia (boo-LEE-me-uh) nervosa — commonly called bulimia — is a serious, potentially life-threatening eating disorder. When you have bulimia, you have episodes of bingeing and purging that involve feeling a lack of control over your eating. Many people with bulimia also restrict their eating during the day, which often leads to more binge eating and purging. During these episodes, you typically eat a large amount of food in a short time, and then try to rid yourself of the extra calories in an unhealthy way. Because of guilt, shame and an intense fear of weight gain from overeating, you may force vomiting or you may exercise too much or use other methods, such as laxatives, to get rid of the calories. If you have bulimia, you're probably preoccupied with your weight and body shape, and may judge yourself severely and harshly for your self-perceived flaws. You may be at a normal weight or even a bit overweight. Binge-eating disorder When you have binge-eating disorder, you regularly eat too much food (binge) and feel a lack of control over your eating. You may eat quickly or eat more food than intended, even when you're not hungry, and you may continue eating even long after you're uncomfortably full. After a binge, you may feel guilty, disgusted or ashamed by your behavior and the amount of food eaten. But you don't try to compensate for this behavior with excessive exercise or purging, as someone with bulimia or anorexia might. Embarrassment can lead to eating alone to hide your bingeing. A new round of bingeing usually occurs at least once a week. You may be normal weight, overweight or obese. Rumination disorder Rumination disorder is repeatedly and persistently regurgitating food after eating, but it's not due to a medical condition or another eating disorder such as anorexia, bulimia or binge-eating disorder. Food is brought back up into the mouth without nausea or gagging, and regurgitation may not be intentional. Sometimes regurgitated food is rechewed and reswallowed or spit out. The disorder may result in malnutrition if the food is spit out or if the person eats significantly less to prevent the behavior. The occurrence of rumination disorder may be more common in infancy or in people who have an intellectual disability. Avoidant/restrictive food intake disorder This disorder is characterized by failing to meet your minimum daily nutrition requirements because you don't have an interest in eating; you avoid food with certain sensory characteristics, such as color, texture, smell or taste; or you're concerned about the consequences of eating, such as fear of choking. Food is not avoided because of fear of gaining weight. The disorder can result in significant weight loss or failure to gain weight in childhood, as well as nutritional deficiencies that can cause health problems.",327,Eating Disorders "Iron deficiency anemia signs and symptoms may include: Extreme fatigue Weakness Pale skin Chest pain, fast heartbeat or shortness of breath Headache, dizziness or lightheadedness Cold hands and feet Inflammation or soreness of your tongue Brittle nails Unusual cravings for non-nutritive substances, such as ice, dirt or starch Poor appetite, especially in infants and children with iron deficiency anemia",537,Iron Deficiency Anemia Signs and symptoms of carbon monoxide poisoning may include: Dull headache Weakness Dizziness Nausea or vomiting Shortness of breath Confusion Blurred vision Loss of consciousness Carbon monoxide poisoning can be particularly dangerous for people who are sleeping or intoxicated. People may have irreversible brain damage or even die before anyone realizes there's a problem.,167,Carbon Monoxide "PLS: Stiffness, weakness and muscle spasms (spasticity) in your legs, rarely starting in one leg, and eventually progressing to your arms, hands, tongue and jaw Slowed movement Tripping, clumsiness and difficulty with balance Hand clumsiness Hoarseness, as well as slowed, slurred speech and drooling Difficulties with chewing and swallowing Sometimes, frequent, rapid and intense shifts in emotions (mood lability) Rarely, breathing problems and bladder problems late in the disease",808,Primary Lateral Sclerosis "Panic attacks typically include some of these signs or symptoms: Sense of impending doom or danger Fear of loss of control or death Rapid, pounding heart rate Sweating Trembling or shaking Shortness of breath or tightness in your throat Chills Hot flashes Nausea Abdominal cramping Chest pain Headache Dizziness, lightheadedness or faintness Numbness or tingling sensation Feeling of unreality or detachment One of the worst things about panic attacks is the intense fear that you'll have another one. You may fear having panic attacks so much that you avoid certain situations where they may occur.",717,Panic Attacks "RLS: Sensations that begin while resting. The sensation typically begins after you've been lying down or sitting for an extended time, such as in a car, airplane or movie theater. Relief with movement. The sensation of RLS lessens with movement, such as stretching, jiggling the legs, pacing or walking. Worsening of symptoms in the evening. Symptoms occur mainly at night. Nighttime leg twitching. RLS may be associated with another, more common condition called periodic limb movement of sleep, which causes the legs to twitch and kick, possibly throughout the night, while you sleep. People typically describe RLS symptoms as compelling, unpleasant sensations in the legs or feet. They usually happen on both sides of the body. Less commonly, the sensations affect the arms. RLS The sensations, which generally occur within the limb rather than on the skin, are described as: Crawling Creeping Pulling Throbbing Aching Itching Electric Sometimes the sensations are difficult to explain. People with RLS usually don't describe the condition as a muscle cramp or numbness. They do, however, consistently describe the desire to move the legs. RLS It's common for symptoms to fluctuate in severity. Sometimes, symptoms disappear for periods of time, then come back.",849,Restless Legs Syndrome "signs and symptoms may include: Changes in skin color — ranging from pale gray to blue, purple, black, bronze or red Swelling Blisters Sudden, severe pain followed by a feeling of numbness A foul-smelling discharge leaking from a sore Thin, shiny skin, or skin without hair Skin that feels cool or cold to the touch If gangrene affects tissues beneath the surface of your skin, such as gas gangrene or internal gangrene, you may also have a low-grade fever and generally feel unwell. If the germs that caused the gangrene spread through the body, a condition called septic shock can occur. Signs and symptoms of septic shock include: Low blood pressure Fever, although some people may have a body temperature lower than 98.6 F (37 C) Rapid heart rate Lightheadedness Shortness of breath Confusion",399,Gangrene "As: Guillain-Barre syndrome progresses, muscle weakness can turn into paralysis. Signs and symptoms of Guillain-Barre syndrome may include: A pins and needles sensation in your fingers, toes, ankles or wrists Weakness in your legs that spreads to your upper body Unsteady walking or inability to walk or climb stairs Difficulty with facial movements, including speaking, chewing or swallowing Double vision or inability to move the eyes Severe pain that may feel achy, shooting or cramplike and may be worse at night Difficulty with bladder control or bowel function Rapid heart rate Low or high blood pressure Difficulty breathing People with Guillain-Barre syndrome usually experience their most significant weakness within two weeks after symptoms begin. Types Guillain-Barre syndrome has several forms. The main types are: Acute inflammatory demyelinating polyradiculoneuropathy (AIDP), the most common form in North America and Europe. The most common sign of AIDP is muscle weakness that starts in the lower part of your body and spreads upward. Miller Fisher syndrome (MFS), in which paralysis starts in the eyes. MFS is also associated with unsteady gait. MFS is less common in the U.S. but more common in Asia. Acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN) are less common in the U.S. But AMAN and AMSAN are more frequent in China, Japan and Mexico.",432,Guillain Barre Syndrome "The first sign of: Merkel cell carcinoma is usually a fast-growing, painless nodule (tumor) on your skin. The nodule may be skin-colored or may appear in shades of red, blue or purple. Most Merkel cell carcinomas appear on the face, head or neck, but they can develop anywhere on your body, even on areas not exposed to sunlight.",620,Merkel Cell Carcinoma "Asthma attack: Asthma attack Asthma attack If you have asthma, the inside walls of the airways in your lungs can become inflamed and swollen. In addition, membranes in your airway linings may secrete excess mucus. The result is an asthma attack. During an asthma attack, your narrowed airways make it harder to breathe, and you may cough and wheeze. Asthma attack Asthma attack Asthma attack Asthma attack If you have asthma, the inside walls of the airways in your lungs can become inflamed and swollen. Asthma attack Asthma attack If you have asthma, the inside walls of the airways in your lungs can become inflamed and swollen. Asthma attack If you have asthma, the inside walls of the airways in your lungs can become inflamed and swollen. If you have asthma, the inside walls of the airways in your lungs can become inflamed and swollen. Occupational asthma signs and symptoms may include: Wheezing, sometimes just at night Coughing Shortness of breath Chest tightness Other possible signs and symptoms may include: Runny nose Nasal congestion Eye irritation and tearing Occupational asthma symptoms depend on the substance you're exposed to, how long and how often you're exposed, and other factors. Your symptoms may: Get worse as the workweek progresses, go away during weekends and vacations, and recur when you return to work. Occur both at work and away from work. Start as soon as you're exposed to an asthma-inducing substance at work or only after a period of regular exposure to the substance. Continue after exposure is stopped. The longer you're exposed to the asthma-causing substance, the more likely you'll have long-lasting or permanent asthma symptoms.",692,Occupational Asthma "But a large ovarian cyst can cause: Pelvic pain that may come and go. You may feel a dull ache or a sharp pain in the area below your bellybutton toward one side. Fullness, pressure or heaviness in your belly (abdomen). Bloating.",707,Ovarian Cysts "Acute phase: The acute phase of Chagas disease, which lasts for weeks or months, is often symptom-free. When signs and symptoms do occur, they are usually mild and may include: Swelling at the infection site Fever Fatigue Rash Body aches Eyelid swelling Headache Loss of appetite Nausea, diarrhea or vomiting Swollen glands Enlargement of your liver or spleen Signs and symptoms that develop during the acute phase usually go away on their own. In some cases, if the infection isn't treated, Chagas disease will advance to the chronic phase. Chronic phase Signs and symptoms of the chronic phase of Chagas disease may occur 10 to 20 years after initial infection, or they may never occur. In severe cases, Chagas disease signs and symptoms may include: Irregular heartbeat Heart failure Sudden cardiac arrest Difficulty swallowing due to enlarged esophagus Stomach pain or constipation due to enlarged colon",188,Chagas Disease "General signs and symptoms of most types of vasculitis include: Fever Headache Fatigue Weight loss General aches and pains Other signs and symptoms are related to the parts of the body affected, including: Digestive system. If your stomach or intestines are affected, you may experience pain after eating. Ulcers and perforations are possible and may result in blood in the stool. Ears. Dizziness, ringing in the ears and abrupt hearing loss may occur. Eyes. Vasculitis can make your eyes look red and itch or burn. Giant cell arteritis can cause double vision and temporary or permanent blindness in one or both eyes. This is sometimes the first sign of the disease. Hands or feet. Some types of vasculitis can cause numbness or weakness in a hand or foot. The palms of the hands and soles of the feet might swell or harden. Lungs. You may develop shortness of breath or even cough up blood if vasculitis affects your lungs. Skin. Bleeding under the skin can show up as red spots. Vasculitis can also cause lumps or open sores on your skin.",1049,Vasculitis "Achilles tendinitis: Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis Achilles tendinitis Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. Achilles tendinitis is an overuse injury of the Achilles (uh-KILL-eez) tendon, the band of tissue that connects calf muscles at the back of the lower leg to your heel bone. The pain associated with Achilles tendinitis typically begins as a mild ache in the back of the leg or above the heel after running or other sports activity. Episodes of more-severe pain may occur after prolonged running, stair climbing or sprinting. You might also experience tenderness or stiffness, especially in the morning, which usually improves with mild activity.",4,Achilles Tendinitis "Trichinella cysts: Trichinella cysts Trichinella cysts After you eat roundworm (trichinella) larvae, they grow into adult worms in your small intestine. The adults then produce larvae that move through the bloodstream to muscle tissues, shown here. Trichinella cysts Trichinella cysts Trichinella cysts Trichinella cysts After you eat roundworm (trichinella) larvae, they grow into adult worms in your small intestine. Trichinella cysts Trichinella cysts After you eat roundworm (trichinella) larvae, they grow into adult worms in your small intestine. Trichinella cysts After you eat roundworm (trichinella) larvae, they grow into adult worms in your small intestine. After you eat roundworm (trichinella) larvae, they grow into adult worms in your small intestine. Signs and symptoms of trichinosis infection and how severe the infection is can vary. This depends on the number of larvae eaten in the infected meat. Possibly no signs or symptoms Mild cases of trichinosis — those with only a small number of parasites in your body — may cause no signs or symptoms. Symptoms can develop with moderate or heavy infestation ⸺ a large number of parasites in your body. These symptoms sometimes get worse as the roundworm (trichinella) larvae travel through your body. Initial signs and symptoms You swallow roundworm (trichinella) larvae in tiny sacks (cysts) containing the parasite. Your digestive juices dissolve the cysts, releasing the larvae into your body. The larvae then enter the wall of your small intestine, where they grow into adult worms and mate. Digestive symptoms can begin 1 to 2 days after infection. At this stage, you may experience: Diarrhea Stomach (abdominal) pain Severe tiredness and weakness (fatigue) Nausea and vomiting Later signs and symptoms About a week after infection, the adult female worms produce larvae. The larvae go through the wall of your intestine and enter your bloodstream, They travel around the body and bury themselves in muscle tissue. Here, each larva coils up and forms a cyst around itself. The larvae can live for months to years inside the muscle tissue. Symptoms caused by muscle tissue invasion usually start 2 to 8 weeks after infection and include: High fever and chills Muscle pain and tenderness Aching joints Swelling of the eyelids or face Weakness Headache Sensitivity to light Pink eye (conjunctivitis) Itchy, irritated skin With a large number of parasites, muscle pain and weakness can be severe. This can limit moving, breathing and speaking. Symptoms last for several months. But symptoms generally lessen when the larvae form cysts. Even after the infection is gone, fatigue, mild pain, weakness and diarrhea may last for months or years.",1010,Trichinosis "Head lice: Head lice Head lice Head lice feed on blood from the scalp. The female louse lays eggs (nits) that stick to hair shafts. Head lice Head lice Head lice Head lice Head lice feed on blood from the scalp. Head lice Head lice Head lice feed on blood from the scalp. Head lice Head lice feed on blood from the scalp. Head lice feed on blood from the scalp. Common signs and symptoms of lice include: Intense itching on the scalp, body or in the genital area. A tickling feeling from movement of hair. The presence of lice on your scalp, body, clothing, or pubic or other body hair. Adult lice may be about the size of a sesame seed or slightly larger. Lice eggs (nits) on hair shafts. Nits may be difficult to see because they're very tiny. They're easiest to spot around the ears and the nape of the neck. Nits can be mistaken for dandruff, but unlike dandruff, they can't be easily brushed out of hair. Sores on the scalp, neck and shoulders. Scratching can lead to small red bumps that can sometimes get infected with bacteria. Bite marks, especially around the waist, groin, upper thighs and pubic area.",574,Lice such as: Fluttering Pounding or jumping Skipped beats or missed beats Increased awareness of the heartbeat,799,Premature Ventricular Contractions "Cellulite looks like dimpled or bumpy skin. It's sometimes described as having a cottage cheese or orange peel texture. You can see mild cellulite only if you pinch your skin in an area where you have cellulite, such as your thighs. Cellulite that is more severe makes the skin appear rumpled and bumpy with areas of peaks and valleys. Cellulite is most common around the thighs and buttocks, but it can also be found on the breasts, lower abdomen and upper arms.",180,Cellulite "Farsightedness may mean: Nearby objects may appear blurry You need to squint to see clearly You have eyestrain, including burning eyes, and aching in or around the eyes You have general eye discomfort or a headache after doing close tasks, such as reading, writing, computer work or drawing, for a time",369,Farsightedness "IgA: Signs and symptoms of IgA nephropathy include: IgA Cola- or tea-colored urine (caused by red blood cells in the urine) Repeated episodes of cola- or tea-colored urine, and sometimes visible blood in your urine, usually during or after an upper respiratory or other infection and sometimes after strenuous exercise Foamy urine from protein leaking into your urine (proteinuria) Pain in the one or both sides of your back below your ribs Swelling (edema) in your hands and feet High blood pressure",513,Iga Nephropathy "include the following: Tiredness Bone pain Broken bones Kidney stones Ulcers in the stomach or intestines Symptoms are caused by the release of too many hormones in the body. By Mayo Clinic Staff By Mayo Clinic Staff Multiple endocrine neoplasia, type 1 (MEN 1) care at Mayo Clinic",610,Men 1 "Signs and symptoms of norovirus infection may start suddenly and include: Nausea Vomiting Stomach pain or cramps Watery or loose diarrhea Feeling ill Low-grade fever Muscle pain Signs and symptoms usually begin 12 to 48 hours after your first exposure to a norovirus and last 1 to 3 days. You can continue to shed virus in your stool for several weeks after recovery. This shedding can last weeks to months if you have another medical condition. Some people with norovirus infection may show no signs or symptoms. However, they're still contagious and can spread the virus to others.",688,Norovirus "Local recurrence: In a local recurrence, cancer reappears in the same area as your original cancer. If you've undergone a lumpectomy, the cancer could recur in the remaining breast tissue. If you've undergone a mastectomy, the cancer could recur in the tissue that lines the chest wall or in the skin. Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness Changes to the skin of your breast Skin inflammation or area of redness Nipple discharge Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall A new area of thickening along or near the mastectomy scar Regional recurrence A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm Near your collarbone In the groove above your collarbone In your neck Distant recurrence A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain Persistent cough Difficulty breathing Loss of appetite Weight loss without trying Severe headaches Seizures",845,Recurrent Breast Cancer "Heart murmur symptoms may include: Blue or gray fingernails or lips Chest pain Cough that doesn't go away Dizziness Swollen liver Swollen neck veins Fainting Heavy sweating with little or no activity In infants, poor appetite and lack of growth Shortness of breath Swelling or sudden weight gain",450,Heart Murmurs "Symptoms may include: Upset stomach, or feeling like you could throw up. Stomachache or stomach pain. Not wanting to eat. Loose stools. Diarrhea. Weight loss. Gas. Hunger pains. Cravings for salty food. Larval cyst infection Symptoms of larval cyst infection depend on where they are causing disease in the body. Larval cysts in the brain or spine. These may cause: Headache. Seizures. Dizziness. Nerve pain in the spine or limbs. Muscle weakness. Poor coordination. Changes in thinking or behaviors. Larval cysts in other organs. These can affect how well the organ works. For example, larval cysts can cause severe disease in the liver, lungs or heart. Symptoms vary widely. In some cases, a lump can be felt. There also may be pain and swelling at the site of the larval cyst infection.",968,Tapeworm "Common anxiety signs and symptoms include: Feeling nervous, restless or tense Having a sense of impending danger, panic or doom Having an increased heart rate Breathing rapidly (hyperventilation) Sweating Trembling Feeling weak or tired Trouble concentrating or thinking about anything other than the present worry Having trouble sleeping Experiencing gastrointestinal (GI) problems Having difficulty controlling worry Having the urge to avoid things that trigger anxiety Several types of anxiety disorders exist: Agoraphobia (ag-uh-ruh-FOE-be-uh) is a type of anxiety disorder in which you fear and often avoid places or situations that might cause you to panic and make you feel trapped, helpless or embarrassed. Anxiety disorder due to a medical condition includes symptoms of intense anxiety or panic that are directly caused by a physical health problem. Generalized anxiety disorder includes persistent and excessive anxiety and worry about activities or events — even ordinary, routine issues. The worry is out of proportion to the actual circumstance, is difficult to control and affects how you feel physically. It often occurs along with other anxiety disorders or depression. Panic disorder involves repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes (panic attacks). You may have feelings of impending doom, shortness of breath, chest pain, or a rapid, fluttering or pounding heart (heart palpitations). These panic attacks may lead to worrying about them happening again or avoiding situations in which they've occurred. Selective mutism is a consistent failure of children to speak in certain situations, such as school, even when they can speak in other situations, such as at home with close family members. This can interfere with school, work and social functioning. Separation anxiety disorder is a childhood disorder characterized by anxiety that's excessive for the child's developmental level and related to separation from parents or others who have parental roles. Social anxiety disorder (social phobia) involves high levels of anxiety, fear and avoidance of social situations due to feelings of embarrassment, self-consciousness and concern about being judged or viewed negatively by others. Specific phobias are characterized by major anxiety when you're exposed to a specific object or situation and a desire to avoid it. Phobias provoke panic attacks in some people. Substance-induced anxiety disorder is characterized by symptoms of intense anxiety or panic that are a direct result of misusing drugs, taking medications, being exposed to a toxic substance or withdrawal from drugs. Other specified anxiety disorder and unspecified anxiety disorder are terms for anxiety or phobias that don't meet the exact criteria for any other anxiety disorders but are significant enough to be distressing and disruptive.",61,Anxiety "Signs and symptoms of rheumatoid arthritis may include: Tender, warm, swollen joints Joint stiffness that is usually worse in the mornings and after inactivity Fatigue, fever and loss of appetite Early rheumatoid arthritis tends to affect your smaller joints first — particularly the joints that attach your fingers to your hands and your toes to your feet. As the disease progresses, symptoms often spread to the wrists, knees, ankles, elbows, hips and shoulders. In most cases, symptoms occur in the same joints on both sides of your body. About 40% of people who have rheumatoid arthritis also experience signs and symptoms that don't involve the joints. Areas that may be affected include: Skin Eyes Lungs Heart Kidneys Salivary glands Nerve tissue Bone marrow Blood vessels Rheumatoid arthritis signs and symptoms may vary in severity and may even come and go. Periods of increased disease activity, called flares, alternate with periods of relative remission — when the swelling and pain fade or disappear. Over time, rheumatoid arthritis can cause joints to deform and shift out of place.",859,Rheumatoid Arthritis "Squamous cell carcinoma of the skin most often occurs on sun-exposed skin, such as your scalp, the backs of your hands, your ears or your lips. But it can occur anywhere on your body, including inside your mouth, the bottoms of your feet and on your genitals. Signs and symptoms of squamous cell carcinoma of the skin include: A firm, red nodule A flat sore with a scaly crust A new sore or raised area on an old scar or ulcer A rough, scaly patch on your lip that may evolve to an open sore A red sore or rough patch inside your mouth A red, raised patch or wartlike sore on or in the anus or on your genitals",937,Squamous Cell Carcinoma "Signs and symptoms of a growth plate fracture may include: Pain and tenderness, particularly in response to pressure on the growth plate Inability to move the affected area or to put weight or pressure on the limb Warmth and swelling at the end of a bone, near a joint When to see a doctor If you suspect a fracture, take your child to be examined by a doctor. Also have your child evaluated if you notice a visible deformity in your child's arms or legs, or if your child is having trouble playing sports because of persistent pain.",431,Growth Plate Fractures "Bubonic plague: Bubonic plague is the most common variety of the disease. It's named after the swollen lymph nodes (buboes) that typically develop in the first week after you become infected. Buboes may be: Situated in the groin, armpit or neck About the size of a chicken egg Tender and firm to the touch Other bubonic plague signs and symptoms may include: Sudden onset of fever and chills Headache Fatigue or malaise Muscle aches Septicemic plague Septicemic plague occurs when plague bacteria multiply in your bloodstream. Signs and symptoms include: Fever and chills Extreme weakness Abdominal pain, diarrhea and vomiting Bleeding from your mouth, nose or rectum, or under your skin Shock Blackening and death of tissue (gangrene) in your extremities, most commonly your fingers, toes and nose Pneumonic plague Pneumonic plague affects the lungs. It's the least common variety of plague but the most dangerous, because it can be spread from person to person via cough droplets. Signs and symptoms can begin within a few hours after infection, and may include: Cough, with bloody mucus (sputum) Difficulty breathing Nausea and vomiting High fever Headache Weakness Chest pain Pneumonic plague progresses rapidly and may cause respiratory failure and shock within two days of infection. Pneumonic plague needs to be treated with antibiotics within a day after signs and symptoms first appear, or the infection is likely to be fatal.",763,Plague "Signs and symptoms of spontaneous bleeding include: Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work Many large or deep bruises Unusual bleeding after vaccinations Pain, swelling or tightness in your joints Blood in your urine or stool Nosebleeds without a known cause In infants, unexplained irritability Bleeding into the brain A simple bump on the head can cause bleeding into the brain for some people who have severe hemophilia. This rarely happens, but it's one of the most serious complications that can occur. Signs and symptoms include: Painful, prolonged headache Repeated vomiting Sleepiness or lethargy Double vision Sudden weakness or clumsiness Convulsions or seizures",461,Hemophilia "including diarrhea or constipation or a change in the consistency of your stool: Rectal bleeding or blood in your stool Persistent abdominal discomfort, such as cramps, gas or pain A feeling that your bowel doesn't empty completely Weakness or fatigue Unexplained weight loss Many people with colon cancer experience no symptoms in the early stages of the disease. When symptoms appear, they'll likely vary, depending on the cancer's size and location in your large intestine.",231,Colon Cancer "They include: Blurred or distorted vision Increased sensitivity to bright light and glare, which can cause problems with night driving A need for frequent changes in eyeglass prescriptions Sudden worsening or clouding of vision",550,Keratoconus "The most common signs and symptoms of acute flaccid myelitis include: Sudden arm or leg weakness Sudden loss of muscle tone Sudden loss of reflexes Other possible signs and symptoms include: Difficulty moving the eyes or drooping eyelids Facial droop or weakness Difficulty with swallowing or slurred speech Pain in the arms, legs, neck or back Uncommon symptoms might include: Numbness or tingling Inability to pass urine Severe symptoms involve respiratory failure, due to the muscles involved in breathing becoming weak. It's also possible to experience life-threatening body temperature changes and blood pressure instability.",12,Acute Flaccid Myelitis "Mild kyphosis may produce no noticeable signs or symptoms. In fact, the upper back naturally has a little kyphosis. People who have excessive curvature may experience back pain and stiffness.",562,Kyphosis "Examples include: Headache. Confusion or changes in speech. Chest pain. Shortness of breath and nausea. Weakness. Burning pain in the hands or feet. Less commonly, very high platelet levels may cause bleeding. This can cause: Nosebleeds. Bruising. Bleeding from your mouth or gums. Bloody stool.",984,Thrombocytosis "Ischemic priapism: Ischemic priapism, also called low-flow priapism, is the result of blood not being able to leave the penis. Blood is trapped in the penis because it cannot flow out of the veins of the penis or there is a problem with the contraction of smooth muscles within the erectile tissue of the penis. Ischemic priapism is the more common type of priapism and requires immediate medical care to prevent complications caused by not getting enough oxygen to the penile tissue. Signs and symptoms include: Erection lasting more than four hours or unrelated to sexual interest or stimulation Rigid penile shaft, but the tip of penis (glans) is soft Progressively worsening penile pain Stuttering priapism — also called recurrent or intermittent priapism — is a form of ischemic priapism. An uncommon condition, stuttering priapism describes repetitive episodes of prolonged erections and often includes episodes of ischemic priapism. It occurs more often in males who have an inherited disorder characterized by abnormally shaped red blood cells (sickle cell disease). Sickle cells can block the blood vessels in the penis. In some cases, the condition starts off with unwanted and painful erections of short duration and might progress over time to more-frequent and more-prolonged erections. Stuttering priapism may begin in childhood. Nonischemic priapism Nonischemic priapism, also known as high-flow priapism, occurs when blood flow through the arteries of the penis isn't working properly. However, the penile tissues continue to receive some blood flow and oxygen. Nonischemic priapism often occurs due to trauma. Signs and symptoms include: Erection lasting more than four hours or unrelated to sexual interest or stimulation Erect but not fully rigid penile shaft Usually not painful",804,Priapism "people infected with the: Zika virus have no signs or symptoms. When symptoms do occur, they usually begin two to 14 days after a person is bitten by an infected mosquito. Symptoms usually last about a week, and most people recover fully. Signs and symptoms of the Zika virus most commonly include: Mild fever Rash Joint pain, particularly in the hands or feet Red eyes (conjunctivitis) Other signs and symptoms may include: Muscle pain Headache Eye pain Fatigue or a general feeling of discomfort Abdominal pain",1080,Zika Virus "SAD: Feeling listless, sad or down most of the day, nearly every day Losing interest in activities you once enjoyed Having low energy and feeling sluggish Having problems with sleeping too much Experiencing carbohydrate cravings, overeating and weight gain Having difficulty concentrating Feeling hopeless, worthless or guilty Having thoughts of not wanting to live Fall and winter SAD Symptoms specific to winter-onset SAD, sometimes called winter depression, may include: SAD Oversleeping Appetite changes, especially a craving for foods high in carbohydrates Weight gain Tiredness or low energy Spring and summer SAD Symptoms specific to summer-onset seasonal affective disorder, sometimes called summer depression, may include: Trouble sleeping (insomnia) Poor appetite Weight loss Agitation or anxiety Increased irritability Seasonal changes and bipolar disorder People who have bipolar disorder are at increased risk of seasonal affective disorder. In some people with bipolar disorder, episodes of mania may be linked to a specific season. For example, spring and summer can bring on symptoms of mania or a less intense form of mania (hypomania), anxiety, agitation and irritability. They may also experience depression during the fall and winter months.",890,Seasonal Affective Disorder "The most common signs and symptoms include: Skin changes. A violet-colored or dusky red rash develops, most commonly on your face and eyelids and on your knuckles, elbows, knees, chest and back. The rash, which can be itchy and painful, is often the first sign of dermatomyositis. Muscle weakness. Progressive muscle weakness involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen.",281,Dermatomyositis "Before school: Signs that a young child may be at risk of dyslexia include: Late talking Learning new words slowly Problems forming words correctly, such as reversing sounds in words or confusing words that sound alike Problems remembering or naming letters, numbers and colors Difficulty learning nursery rhymes or playing rhyming games School age Once your child is in school, dyslexia symptoms may become more apparent, including: Reading well below the expected level for age Problems processing and understanding what is heard Difficulty finding the right word or forming answers to questions Problems remembering the sequence of things Difficulty seeing (and occasionally hearing) similarities and differences in letters and words Inability to sound out the pronunciation of an unfamiliar word Difficulty spelling Spending an unusually long time completing tasks that involve reading or writing Avoiding activities that involve reading Teens and adults Dyslexia signs in teens and adults are a lot like those in children. Some common dyslexia symptoms in teens and adults include: Difficulty reading, including reading aloud Slow and labor-intensive reading and writing Problems spelling Avoiding activities that involve reading Mispronouncing names or words, or problems retrieving words Spending an unusually long time completing tasks that involve reading or writing Difficulty summarizing a story Trouble learning a foreign language Difficulty doing math word problems",322,Dyslexia "Drug rash: Drug rash Drug rash A drug rash usually starts within two weeks of taking a new medication and begins as discrete red spots that spread, covering large areas of the body. Drug rash Drug rash Drug rash Drug rash A drug rash usually starts within two weeks of taking a new medication and begins as discrete red spots that spread, covering large areas of the body. Drug rash Drug rash A drug rash usually starts within two weeks of taking a new medication and begins as discrete red spots that spread, covering large areas of the body. Drug rash A drug rash usually starts within two weeks of taking a new medication and begins as discrete red spots that spread, covering large areas of the body. A drug rash usually starts within two weeks of taking a new medication and begins as discrete red spots that spread, covering large areas of the body. Signs and symptoms of penicillin allergy often occur within an hour after taking the drug. Less commonly, reactions can occur hours, days or weeks later. Penicillin allergy signs and symptoms may include: Skin rash Hives Itching Fever Swelling Shortness of breath Wheezing Runny nose Itchy, watery eyes Anaphylaxis Anaphylaxis Anaphylaxis is a rare, life-threatening allergic reaction that causes the widespread dysfunction of body systems. Signs and symptoms of anaphylaxis include: Tightening of the airways and throat, causing trouble breathing Nausea or abdominal cramps Vomiting or diarrhea Dizziness or lightheadedness Weak, rapid pulse Drop in blood pressure Seizures Loss of consciousness Delayed reactions resulting from penicillin allergy Less-common penicillin allergy reactions occur days or weeks after exposure to the drug and may persist for some time after you stop taking it. These conditions include: Serum sickness, which may cause fever, joint pain, rash, swelling and nausea Drug-induced anemia, a reduction in red blood cells, which can cause fatigue, irregular heartbeats, shortness of breath, and other signs and symptoms Drug reaction with eosinophilia and systemic symptoms (DRESS), which results in rash, high white blood cell counts, general swelling, swollen lymph nodes and recurrence of dormant hepatitis infection Stevens-Johnson syndrome or toxic epidermal necrolysis, which involves severe blistering and peeling of the skin Inflammation in the kidneys (nephritis), which can cause fever, blood in the urine, general swelling, confusion, and other signs and symptoms Adverse events that are not allergic reactions You may experience side effects of penicillin — as happens with other medications — that are not an allergic reaction to the drug. Depending on the type of penicillin, common side effects may include mild nausea or diarrhea, headache, or vaginal itching. Signs or symptoms of an infection for which you are being treated — or unrelated symptoms — also may be mistaken as an allergic drug reaction.",733,Penicillin Allergy "Pet allergy signs and symptoms caused by inflammation of nasal passages include: Sneezing Runny nose Itchy, red or watery eyes Nasal congestion Itchy nose, roof of mouth or throat Postnasal drip Cough Facial pressure and pain Frequent awakening Swollen, blue-colored skin under your eyes In a child, frequent upward rubbing of the nose If your pet allergy contributes to asthma, you may also experience: Difficulty breathing Chest tightness or pain Audible whistling or wheezing sound when exhaling Trouble sleeping caused by shortness of breath, coughing or wheezing Skin symptoms Some people with pet allergy may also experience skin symptoms, a pattern known as allergic dermatitis. This type of dermatitis is an immune system reaction that causes skin inflammation. Direct contact with an allergy-causing pet may trigger allergic dermatitis, causing signs and symptoms, such as: Raised, red patches of skin (hives) Eczema Itchy skin",749,Pet Allergy "Yellowing of the skin and the whites of the eyes — the main sign of infant jaundice — usually appears between the second and fourth day after birth. To check for infant jaundice, press gently on your baby's forehead or nose. If the skin looks yellow where you pressed, it's likely your baby has mild jaundice. If your baby doesn't have jaundice, the skin color should simply look slightly lighter than its normal color for a moment. Examine your baby in good lighting conditions, preferably in natural daylight.",519,Infant Jaundice "HUS HUS HUS: Diarrhea, which is often bloody Abdominal pain, cramping or bloating Vomiting Fever All forms of HUS — no matter the cause — damage the blood vessels. This damage causes red blood cells to break down (anemia), blood clots to form in the blood vessels and kidney damage. Signs and symptoms of these changes include: HUS Pale coloring, including loss of pink color in cheeks and inside the lower eyelids Extreme fatigue Shortness of breath Easy bruising or unexplained bruises Unusual bleeding, such as bleeding from the nose and mouth Decreased urination or blood in the urine Swelling (edema) of the legs, feet or ankles, and less often in the face, hands, feet or entire body Confusion, seizures or stroke High blood pressure When to see a doctor See your doctor immediately if you or your child experiences bloody diarrhea or several days of diarrhea followed by: Decreased urine output Swelling Unexplained bruises Unusual bleeding Extreme fatigue Seek emergency care if you or your child doesn't urinate for 12 hours or more.",460,Hemolytic Uremic Syndrome "Signs and symptoms may include: Inability to swallow (dysphagia), which may feel like food or drink is stuck in your throat Regurgitating food or saliva Heartburn Belching Chest pain that comes and goes Coughing at night Pneumonia (from aspiration of food into the lungs) Weight loss Vomiting",3,Achalasia "Immediate signs and symptoms of milk allergy might include: Hives Wheezing Itching or tingling feeling around the lips or mouth Swelling of the lips, tongue or throat Coughing or shortness of breath Vomiting Signs and symptoms that may take more time to develop include: Loose stools or diarrhea, which may contain blood Abdominal cramps Runny nose Watery eyes Colic, in babies Milk allergy or milk intolerance? A true milk allergy differs from milk protein intolerance and lactose intolerance. Unlike milk allergy, intolerance doesn't involve the immune system. Milk intolerance requires different treatment from true milk allergy. Common signs and symptoms of milk protein intolerance or lactose intolerance include digestive problems, such as bloating, gas or diarrhea, after consuming milk or products containing milk. Anaphylaxis Milk allergy can cause anaphylaxis, a life-threatening reaction that narrows the airways and can block breathing. Milk is the third most common food — after peanuts and tree nuts — to cause anaphylaxis. If you or your child has a reaction to milk, tell your health care provider, no matter how mild the reaction. Tests can help confirm milk allergy, so you can avoid future and potentially worse reactions. Anaphylaxis is a medical emergency and requires treatment with an epinephrine (adrenaline) shot (EpiPen, Adrenaclick, others) and a trip to the emergency room. Signs and symptoms start soon after milk consumption and can include: Constriction of airways, including a swollen throat that makes it difficult to breathe Facial flushing Itching Shock, with a marked drop in blood pressure",634,Milk Allergy "Semantic variant primary progressive aphasia: Signs and symptoms include: Difficulty comprehending spoken or written language, particularly single words Trouble comprehending word meanings Struggling to name objects Logopenic variant primary progressive aphasia Signs and symptoms include: Difficulty retrieving words and word substitutions Frequently pausing in speech while searching for words Difficulty repeating phrases or sentences Nonfluent-agrammatic variant primary progressive aphasia Signs and symptoms include: Poor grammar in written and spoken form Trouble understanding complex sentences Using grammar incorrectly May be accompanied by speaking problems such as errors in speech sounds (known as apraxia of speech) Causes Primary progressive aphasia is caused by a shrinking (atrophy) of certain sections (lobes) of the brain responsible for speech and language. In this case, the frontal, temporal or parietal lobes, primarily on the left side of the brain, are affected. Atrophy is associated with the presence of abnormal proteins, and brain activity or function in affected areas might be reduced. Risk factors Risk factors for primary progressive aphasia include: Learning disabilities. If you had a childhood learning disability, particularly developmental dyslexia, you might be at somewhat higher risk of primary progressive aphasia. Certain gene mutations. Rare gene mutations have been linked to the disorder. If other members of your family have had primary progressive aphasia, you might be more likely to develop it. Complications People with primary progressive aphasia eventually lose the ability to speak and write, and to understand written and spoken language. Some people develop substantial difficulty forming sounds to speak (a problem called apraxia of speech), even when their ability to write and comprehend are not significantly impaired. As the disease progresses, other mental skills, such as memory, can become impaired. Some people develop other neurological symptoms such as problems with movement. With these complications, the affected person eventually will need help with day-to-day care. People with primary progressive aphasia can also develop depression or behavioral or social problems as the disease progresses. Other problems might include blunted emotions such as unconcern, poor judgment or inappropriate social behavior. By Mayo Clinic Staff By Mayo Clinic Staff Primary progressive aphasia care at Mayo Clinic",809,Primary Progressive Aphasia "Common signs and symptoms include: Moderate discomfort or pain in your ear Feeling of fullness or stuffiness in your ear Muffled hearing or slight to moderate hearing loss If airplane ear is severe, you might have: Severe pain Increased ear pressure Moderate to severe hearing loss Ringing in your ear (tinnitus) Spinning sensation (vertigo) Bleeding from your ear",28,Airplane Ear "When to see a doctor: Consult your doctor if rest, ice and over-the-counter pain relievers don't ease your shin pain.",903,Shin Splints "Causes: There are no known causes for a sacral dimple. It is a congenital condition, meaning it's present at birth. Complications Rarely, sacral dimples are associated with a serious underlying abnormality of the spine or spinal cord. Examples include: Spina bifida. A very mild form of this condition, called spina bifida occulta, occurs when the spine doesn't close properly around the spinal cord, but the cord remains within the spinal canal. In most cases, spina bifida occulta causes no symptoms and doesn't need treatment. Tethered cord syndrome. The spinal cord normally hangs freely within the spinal canal. Tethered cord syndrome is a disorder that occurs when tissue attached to the spinal cord limits its movements. Signs and symptoms may include weakness or numbness in the legs and bladder or bowel incontinence. The risks of these spinal problems increase if the sacral dimple is accompanied by a nearby tuft of hair, skin tag or lump, and certain types of skin discoloration",871,Sacral Dimple "symptoms can include: Leg swelling Leg pain, cramping or soreness that often starts in the calf Change in skin color on the leg — such as red or purple, depending on the color of your skin A feeling of warmth on the affected leg Deep vein thrombosis can occur without noticeable symptoms.",270,Deep Vein Thrombosis "and may include any of the following: Enlarged hands and feet Enlarged facial features, including the facial bones, lips, nose and tongue Coarse, oily, thickened skin Excessive sweating and body odor Small outgrowths of skin tissue (skin tags) Fatigue and joint or muscle weakness Pain and limited joint mobility A deepened, husky voice due to enlarged vocal cords and sinuses Severe snoring due to obstruction of the upper airway Vision problems Headaches, which may be persistent or severe Menstrual cycle irregularities in women Erectile dysfunction in men Loss of interest in sex",9,Acromegaly the affected joints are usually: Swollen Warm Severely painful,819,Pseudogout "Signs and symptoms of nephrotic syndrome include: Severe swelling (edema), particularly around your eyes and in your ankles and feet Foamy urine, a result of excess protein in your urine Weight gain due to fluid retention Fatigue Loss of appetite",675,Nephrotic Syndrome "Kleptomania symptoms may include: Inability to resist powerful urges to steal items that you don't need Feeling increased tension, anxiety or arousal leading up to the theft Feeling pleasure, relief or satisfaction while stealing Feeling terrible guilt, remorse, self-loathing, shame or fear of arrest after the theft Return of the urges and a repetition of the kleptomania cycle Features People with kleptomania usually have these features or characteristics: Unlike most shoplifters, people with kleptomania don't compulsively steal for personal gain, on a dare, for revenge or out of rebellion. They steal simply because the urge is so powerful that they can't resist it. Episodes of kleptomania generally happen suddenly, without planning and without help from another person. Most people with kleptomania steal from public places, such as stores. Some may steal from friends or acquaintances, such as at a party. Often, the stolen items have no value to the person with kleptomania, and the person can afford to buy them. The stolen items are usually stashed away, never to be used. Items also may be donated, given away to family or friends, or even secretly returned to the place from which they were stolen. Urges to steal may come and go or may occur with greater or lesser intensity over the course of time.",557,Kleptomania "Signs and symptoms of iritis include: Eye redness Discomfort or achiness in the affected eye Sensitivity to light Decreased vision Iritis that develops suddenly, over hours or days, is known as acute iritis. Symptoms that develop gradually or last longer than three months indicate chronic iritis.",536,Iritis "Signs and symptoms of adrenal cancer include: Weight gain Muscle weakness Pink or purple stretch marks on the skin Hormone changes in women that might cause excess facial hair, hair loss on the head and irregular periods Hormone changes in men that might cause enlarged breast tissue and shrinking testicles Nausea Vomiting Abdominal bloating Back pain Fever Loss of appetite Loss of weight without trying Causes It's not clear what causes adrenal cancer. Adrenal cancer forms when something creates changes (mutations) in the DNA of an adrenal gland cell. A cell's DNA contains the instructions that tell a cell what to do. The mutations can tell the cell to multiply uncontrollably and to continue living when healthy cells would die. When this happens, the abnormal cells accumulate and form a tumor. The tumor cells can break away and spread (metastasize) to other parts of the body. Risk factors Adrenal cancer happens more often in people with inherited syndromes that increase the risk of certain cancers. These inherited syndromes include: Beckwith-Wiedemann syndrome Carney complex Li-Fraumeni syndrome Lynch syndrome Multiple endocrine neoplasia, type 1 (MEN 1) By Mayo Clinic Staff By Mayo Clinic Staff Adrenal cancer care at Mayo Clinic",21,Adrenal Cancer Chest pain: Shortness of breath Other symptoms may include: Anxiety Fatigue Lightheadedness or dizziness Sweating Fainting (syncope) or near fainting,446,Heart Arrhythmia "Signs and symptoms of diaper rash include: Inflamed skin in the diaper area — buttocks, thighs and genitals Itchy, tender skin in the diaper area Sores in the diaper area Discomfort, fussiness or crying, especially during diaper changes",293,Diaper Rash "PCOS: The symptoms of PCOS vary. A diagnosis of PCOS is made when you have at least two of these: PCOS PCOS Irregular periods. Having few menstrual periods or having periods that aren't regular are common signs of PCOS. So is having periods that last for many days or longer than is typical for a period. For example, you might have fewer than nine periods a year. And those periods may occur more than 35 days apart. You may have trouble getting pregnant. Too much androgen. High levels of the hormone androgen may result in excess facial and body hair. This is called hirsutism. Sometimes, severe acne and male-pattern baldness can happen, too. Polycystic ovaries. Your ovaries might be bigger. Many follicles containing immature eggs may develop around the edge of the ovary. The ovaries might not work the way they should. PCOS signs and symptoms are typically more severe in people with obesity.",726,Pcos "t go away: Coughing up blood, even a small amount Shortness of breath Chest pain Hoarseness Losing weight without trying Bone pain Headache",589,Lung Cancer "may include: Dizziness A sense that you or your surroundings are spinning or moving (vertigo) A loss of balance or unsteadiness Nausea Vomiting The signs and symptoms of BPPV can come and go and commonly last less than one minute. Episodes of BPPV can disappear for some time and then recur. BPPV BPPV Activities that bring about the signs and symptoms of BPPV can vary from person to person, but are almost always brought on by a change in head position. Some people also feel out of balance when standing or walking. BPPV Abnormal rhythmic eye movements usually accompany the symptoms of benign paroxysmal positional vertigo.",1055,Vertigo I have a lot of heartburn and acid reflux. I also feel sick after eating and sometimes throw up.,403,Gastroesophageal Reflux Disease "The blisters associated with dyshidrosis occur most commonly on the sides of the fingers and the palms. Sometimes the soles of the feet also can be affected. The blisters are usually small — about the width of a standard pencil lead — and grouped in clusters, with an appearance similar to tapioca. In more-severe cases, the small blisters may merge to form larger blisters. Skin affected by dyshidrosis can be painful and very itchy. The blisters dry and flake off in about three weeks. Dyshidrosis tends to recur fairly regularly for months or years.",321,Dyshidrosis "Symptoms of cholera infection can include: Diarrhea. Cholera-related diarrhea comes on suddenly and can quickly cause dangerous fluid loss — as much as a quart (about 1 liter) an hour. Diarrhea due to cholera often has a pale, milky appearance that resembles water in which rice has been rinsed. Nausea and vomiting. Vomiting occurs especially in the early stages of cholera and can last for hours. Dehydration. Dehydration can develop within hours after cholera symptoms start and range from mild to severe. A loss of 10% or more of body weight indicates severe dehydration. Signs and symptoms of cholera dehydration include irritability, fatigue, sunken eyes, a dry mouth, extreme thirst, dry and shriveled skin that's slow to bounce back when pinched into a fold, little or no urinating, low blood pressure, and an irregular heartbeat. Dehydration can lead to a rapid loss of minerals in your blood that maintain the balance of fluids in your body. This is called an electrolyte imbalance. Electrolyte imbalance An electrolyte imbalance can lead to serious signs and symptoms such as: Muscle cramps. These result from the rapid loss of salts such as sodium, chloride and potassium. Shock. This is one of the most serious complications of dehydration. It occurs when low blood volume causes a drop in blood pressure and a drop in the amount of oxygen in your body. If untreated, severe hypovolemic shock can cause death in minutes.",204,Cholera "Signs and symptoms of chronic constipation include: Passing fewer than three stools a week Having lumpy or hard stools Straining to have bowel movements Feeling as though there's a blockage in your rectum that prevents bowel movements Feeling as though you can't completely empty the stool from your rectum Needing help to empty your rectum, such as using your hands to press on your abdomen and using a finger to remove stool from your rectum Constipation may be considered chronic if you've experienced two or more of these symptoms for the last three months.",244,Constipation "Moles: Moles Moles Moles are usually harmless. They may contain hairs or become raised or wrinkled. Talk to your doctor about any change in the color or size of a mole or if itching, pain, bleeding or inflammation develops. Moles Moles Moles Moles Moles are usually harmless. Moles Moles Moles are usually harmless. Moles Moles are usually harmless. Moles are usually harmless. Melanoma Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanoma Melanoma Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. Melanomas can develop anywhere on your body. They most often develop in areas that have had exposure to the sun, such as your back, legs, arms and face. Melanomas can also occur in areas that don't receive much sun exposure, such as the soles of your feet, palms of your hands and fingernail beds. These hidden melanomas are more common in people with darker skin. The first melanoma signs and symptoms often are: A change in an existing mole The development of a new pigmented or unusual-looking growth on your skin Melanoma doesn't always begin as a mole. It can also occur on otherwise normal-appearing skin. Normal moles Normal moles are generally a uniform color such as tan, brown or black with a distinct border separating the mole from your surrounding skin. They're oval or round and usually smaller than 1/4 inch (about 6 millimeters) in diameter the size of a pencil eraser. Most moles begin appearing in childhood and new moles may form until about age 40. By the time they are adults, most people have between 10 and 40 moles. Moles may change in appearance over time and some may even disappear with age. Unusual moles that may indicate melanoma To help you identify characteristics of unusual moles that may indicate melanomas or other skin cancers, think of the letters ABCDE: A is for asymmetrical shape. Look for moles with irregular shapes, such as two very different-looking halves. B is for irregular border. Look for moles with irregular, notched or scalloped borders characteristics of melanomas. C is for changes in color. Look for growths that have many colors or an uneven distribution of color. D is for diameter. Look for new growth in a mole larger than 1/4 inch (about 6 millimeters). E is for evolving. Look for changes over time, such as a mole that grows in size or that changes color or shape. Moles may also evolve to develop new signs and symptoms, such as new itchiness or bleeding. Cancerous (malignant) moles vary greatly in appearance. Some may show all of the changes listed above, while others may have only one or two unusual characteristics. Hidden melanomas Melanomas can also develop in areas of your body that have little or no exposure to the sun, such as the spaces between your toes and on your palms, soles, scalp or genitals. These are sometimes referred to as hidden melanomas because they occur in places most people wouldn't think to check. When melanoma occurs in people with darker skin, it's more likely to occur in a hidden area. Hidden melanomas include: Melanoma under a nail. Acral-lentiginous melanoma is a rare form of melanoma that can occur under a fingernail or toenail. It can also be found on the palms of the hands or the soles of the feet. It's more common in people of Asian descent, black people and in others with dark skin pigment. Melanoma in the mouth, digestive tract, urinary tract or vagina. Mucosal melanoma develops in the mucous membrane that lines the nose, mouth, esophagus, anus, urinary tract and vagina. Mucosal melanomas are especially difficult to detect because they can easily be mistaken for other far more common conditions. Melanoma in the eye. Eye melanoma, also called ocular melanoma, most often occurs in the uvea the layer beneath the white of the eye (sclera). An eye melanoma may cause vision changes and may be diagnosed during an eye exam.",609,Melanoma "they might include: Shortness of breath or difficulty breathing (dyspnea) Discomfort when breathing while lying down Chest pain, usually behind the breastbone or on the left side of the chest Chest fullness Lightheadedness or feeling faint Swelling in the abdomen or legs",737,Pericardial Effusion "Fundal height: Fundal height is the distance from the pubic bone to the top of the uterus measured in centimeters. After 24 weeks of pregnancy, fundal height often matches the number of weeks you've been pregnant. Polyhydramnios In polyhydramnios, excessive amniotic fluid accumulates in the uterus during pregnancy. Mild cases of polyhydramnios may go away on their own. Severe cases may require treatment. In polyhydramnios, excessive amniotic fluid accumulates in the uterus during pregnancy. Fetal macrosomia can be difficult to detect and diagnose during pregnancy. Signs and symptoms include: Large fundal height. During prenatal visits, your health care provider might measure your fundal height the distance from the top of your uterus to your pubic bone. A larger than expected fundal height could be a sign of fetal macrosomia. Excessive amniotic fluid (polyhydramnios). Having too much amniotic fluid the fluid that surrounds and protects a baby during pregnancy might be a sign that your baby is larger than average. The amount of amniotic fluid reflects your baby's urine output, and a larger baby produces more urine. Some conditions that cause a baby to be larger might also increase his or her urine output.",375,Fetal Macrosomia "Common warts: Common warts Common warts Common warts can grow on your hands or fingers. They're small, grainy bumps that are rough to the touch. Common warts Common warts Common warts Common warts Common warts can grow on your hands or fingers. Common warts Common warts Common warts can grow on your hands or fingers. Common warts Common warts can grow on your hands or fingers. Common warts can grow on your hands or fingers. Plantar warts Plantar warts Plantar warts Plantar warts are caused by the same type of virus that causes warts on your hands and fingers. But, because of their location, they can be painful. Plantar warts Plantar warts Plantar warts Plantar warts Plantar warts are caused by the same type of virus that causes warts on your hands and fingers. Plantar warts Plantar warts Plantar warts are caused by the same type of virus that causes warts on your hands and fingers. Plantar warts Plantar warts are caused by the same type of virus that causes warts on your hands and fingers. Plantar warts are caused by the same type of virus that causes warts on your hands and fingers. Flat warts Flat warts Flat warts Flat warts are smaller and smoother than other warts. They generally occur on the face or legs and are more common in children and teens than in adults. Flat warts Flat warts Flat warts Flat warts Flat warts are smaller and smoother than other warts. Flat warts Flat warts Flat warts are smaller and smoother than other warts. Flat warts Flat warts are smaller and smoother than other warts. Flat warts are smaller and smoother than other warts. Female genital warts Female genital warts Female genital warts Genital warts are a common sexually transmitted infection. They can appear on the genitals, in the pubic area or in the anal canal. In women, genital warts can also grow inside the vagina. Female genital warts Female genital warts Female genital warts Female genital warts Genital warts are a common sexually transmitted infection. Female genital warts Female genital warts Genital warts are a common sexually transmitted infection. Female genital warts Genital warts are a common sexually transmitted infection. Genital warts are a common sexually transmitted infection. Male genital warts Male genital warts Male genital warts Genital warts are a common sexually transmitted infection. Male genital warts Male genital warts Male genital warts Male genital warts Genital warts are a common sexually transmitted infection. Male genital warts Male genital warts Genital warts are a common sexually transmitted infection. Male genital warts Genital warts are a common sexually transmitted infection. In most cases, your body's immune system defeats an HPV infection before it creates warts. When warts do appear, they vary in appearance depending on which kind of HPV is involved: HPV HPV Genital warts. These appear as flat lesions, small cauliflower-like bumps or tiny stemlike protrusions. In women, genital warts appear mostly on the vulva but can also occur near the anus, on the cervix or in the vagina. In men, genital warts appear on the penis and scrotum or around the anus. Genital warts rarely cause discomfort or pain, though they may itch or feel tender. Common warts. Common warts appear as rough, raised bumps and usually occur on the hands and fingers. In most cases, common warts are simply unsightly, but they can also be painful or susceptible to injury or bleeding. Plantar warts. Plantar warts are hard, grainy growths that usually appear on the heels or balls of your feet. These warts might cause discomfort. Flat warts. Flat warts are flat-topped, slightly raised lesions. They can appear anywhere, but children usually get them on the face and men tend to get them in the beard area. Women tend to get them on the legs. Cervical cancer Nearly all cervical cancers are caused by HPV infections, but cervical cancer may take 20 years or longer to develop after an HPV infection. The HPV infection and early cervical cancer typically don't cause noticeable symptoms. Getting vaccinated against HPV infection is your best protection from cervical cancer. HPV HPV HPV HPV Because early cervical cancer doesn't cause symptoms, it's vital that women have regular screening tests to detect any precancerous changes in the cervix that might lead to cancer. Current guidelines recommend that women ages 21 to 29 have a Pap test every three years. Women ages 30 to 65 are advised to continue having a Pap test every three years, or every five years if they also get the HPV DNA test at the same time. Women over 65 can stop testing if they've had three normal Pap tests in a row, or two HPV DNA and Pap tests with no abnormal results.",489,Hpv Infection "and may include: Increased thirst Frequent urination, possibly bed-wetting in a toilet-trained child Extreme hunger Unintentional weight loss Fatigue Irritability or behavior changes Fruity-smelling breath",1023,Type 1 Diabetes In Children "Signs and symptoms of mononucleosis may include: Fatigue Sore throat, perhaps misdiagnosed as strep throat, that doesn't get better after treatment with antibiotics Fever Swollen lymph nodes in your neck and armpits Swollen tonsils Headache Skin rash Soft, swollen spleen The virus has an incubation period of about four to six weeks, although in young children this period may be shorter. The incubation period refers to how long before your symptoms appear after being exposed to the virus. Signs and symptoms such as a fever and sore throat usually lessen within a couple of weeks. But fatigue, enlarged lymph nodes and a swollen spleen may last for a few weeks longer. When to see your doctor If you've been experiencing the above symptoms, you may have mononucleosis. If your symptoms don't get better on their own in a week or two, see your doctor.",645,Mononucleosis "Signs and symptoms at the site of a scorpion sting may include: Pain, which can be intense Numbness and tingling Slight swelling Warmth Signs and symptoms related to widespread (systemic) venom effects usually occur in children who are stung and may include: Difficulty breathing Muscle twitching or thrashing Unusual head, neck and eye movements Drooling Sweating Nausea and vomiting High blood pressure (hypertension) Accelerated heart rate (tachycardia) Restlessness or excitability, or inconsolable crying in children As with other stinging insects, such as bees and wasps, it is possible for people who have previously been stung by scorpions to have allergic reactions with subsequent stings. Reactions to these subsequent stings are sometimes severe enough to cause a life-threatening condition called anaphylaxis. Signs and symptoms in these cases are similar to those of anaphylaxis caused by bee stings and can include hives, trouble breathing, and nausea and vomiting.",888,Scorpion Stings "The most common sign of: Wolff-Parkinson-White (WPW) syndrome is a heart rate greater than 100 beats a minute. Episodes of a fast heart rate (tachycardia) can begin suddenly and may last a few seconds or several hours. Episodes can occur during exercise or while at rest. Other signs and symptoms of WPW syndrome are related to the fast heart rate and underlying heart rhythm problem (arrhythmia). The most common arrhythmia seen with WPW syndrome is supraventricular tachycardia. Supraventricular tachycardia causes episodes of a fast, pounding heartbeat that begin and end abruptly. Some people with WPW syndrome also have a fast and chaotic heart rhythm problem called atrial fibrillation. WPW WPW WPW In general, signs and symptoms that may occur in people with WPW syndrome include: WPW A rapid, fluttering or pounding heartbeat (palpitations) Chest pain Difficulty breathing Dizziness or lightheadedness Fainting Fatigue Shortness of breath Anxiety Symptoms in infants Signs and symptoms of WPW syndrome in infants can include: WPW Pale or faded skin color (pallor) Blue or gray coloring to the skin, lips and nails (cyanosis) Restlessness or irritability Rapid breathing Poor eating Some people with an extra electrical pathway don't have signs or symptoms of a fast heartbeat. This condition is called Wolff-Parkinson-White (WPW) pattern. It's often discovered by chance during a heart test.",1074,Wolff Parkinson White Syndrome "Common symptoms of endocarditis include: Aching joints and muscles Chest pain when you breathe Fatigue Flu-like symptoms, such as fever and chills Night sweats Shortness of breath Swelling in the feet, legs or belly A new or changed whooshing sound in the heart (murmur) Less common endocarditis symptoms can include: Unexplained weight loss Blood in the urine Tenderness under the left rib cage (spleen) Painless red, purple or brown flat spots on the soles bottom of the feet or the palms of the hands (Janeway lesions) Painful red or purple bumps or patches of darkened skin (hyperpigmented) on the tips of the fingers or toes (Osler nodes) Tiny purple, red or brown round spots on the skin (petechiae), in the whites of the eyes or inside the mouth",340,Endocarditis "Common signs and symptoms of acoustic neuroma include: Hearing loss, usually gradually worsening over months to years — although in rare cases sudden — and occurring on only one side or more severe on one side Ringing (tinnitus) in the affected ear Unsteadiness or loss of balance Dizziness (vertigo) Facial numbness and weakness or loss of muscle movement In rare cases, an acoustic neuroma may grow large enough to compress the brainstem and become life-threatening. When to see your doctor See your doctor if you notice hearing loss in one ear, ringing in your ear or trouble with your balance. Early diagnosis of an acoustic neuroma may help keep the tumor from growing large enough to cause serious consequences, such as total hearing loss.",8,Acoustic Neuroma "Signs and symptoms of: Charcot-Marie-Tooth disease may include: Weakness in your legs, ankles and feet Loss of muscle bulk in your legs and feet High foot arches Curled toes (hammertoes) Decreased ability to run Difficulty lifting your foot at the ankle (footdrop) Awkward or higher than normal step (gait) Frequent tripping or falling Decreased sensation or a loss of feeling in your legs and feet As Charcot-Marie-Tooth disease progresses, symptoms may spread from the feet and legs to the hands and arms. The severity of symptoms can vary greatly from person to person, even among family members. Causes Charcot-Marie-Tooth disease is an inherited, genetic condition. It occurs when there are mutations in the genes that affect the nerves in your feet, legs, hands and arms. Sometimes, these mutations damage the nerves. Other mutations damage the protective coating that surrounds the nerve (myelin sheath). Both cause weaker messages to travel between your limbs and brain. Risk factors Charcot-Marie-Tooth disease is hereditary, so you're at higher risk of developing the disorder if anyone in your immediate family has the disease. Other causes of neuropathies, such as diabetes, may cause symptoms similar to Charcot-Marie-Tooth disease. These other conditions can also cause the symptoms of Charcot-Marie-Tooth disease to become worse. Medications such as the chemotherapy drugs vincristine (Marqibo), paclitaxel (Abraxane) and others can make symptoms worse. Be sure to let your doctor know about all of the medications you're taking. Complications Complications of Charcot-Marie-Tooth disease vary in severity from person to person. Foot abnormalities and difficulty walking are usually the most serious problems. Muscles may get weaker, and you may injure areas of the body that experience decreased sensation. Sometimes the muscles in your feet may not receive your brain's signal to contract, so you're more likely to trip and fall. And your brain may not receive pain messages from your feet, so if you've rubbed a blister on your toe, for example, it may get infected without your realizing it. You may also experience difficulty breathing, swallowing or speaking if the muscles that control these functions are affected by Charcot-Marie-Tooth disease. By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment March 08, 2023 Print Print Share on: FacebookTwitter Facebook Twitter Show references Klein CJ. Charcot-Marie-Tooth disease and other hereditary neuropathies. Continuum. 2020; doi:10.1212/CON.0000000000000927. Charcot-Marie-Tooth disease fact sheet. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Charcot-Marie-Tooth-Disease-Fact-Sheet. Accessed Dec. 31, 2020. Kang PB. Charcot-Marie-Tooth disease: Genetics, clinical features and diagnosis. https://www.uptodate.com/contents/search. Facts about Charcot-Marie-Tooth disease and related diseases. Muscular Dystrophy Association. https://www.mda.org/disease/charcot-marie-tooth. Neurotoxic medications. Charcot-Marie-Tooth Association. https://www.cmtausa.org/living-with-cmt/managing-cmt/medications/. Simon RP, et al. Sensory disorders. In: Clinical Neurology. 10th ed. McGraw-Hill; 2018. https://accessmedicine.mhmedical.com. Charcot-Marie-Tooth disease: Management and prognosis. Rossor AM, et al. Are we prepared for clinical trials in Charcot-Marie-Tooth disease? Brain Research. 2020; doi:10.1016/j.brainres.2019.146625. Pareyson D, et al. New developments in Charcot-Marie-Tooth neuropathy and related diseases. Current Opinion in Neurology. 2017; doi:10.1097/WCO. 0000000000000474. Important foot care for people with CMT. https://www.cmtausa.org/living-with-cmt/managing-cmt/important-foot-care-for-people-with-cmt/. Pedicure pointers. American Podiatric Medical Association. https://www.apma.org/Patients/HealthyFeetTips.cfm?ItemNumber=9859. Show references Klein CJ. Klein CJ. 2019.146625 2019.146625 Pareyson D, et al. Related Associated Procedures Electromyography (EMG) Gene therapy Genetic testing Knee braces for osteoarthritis Show more associated procedures Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Related Associated Procedures Electromyography (EMG) Gene therapy Genetic testing Knee braces for osteoarthritis Show more associated procedures Associated Procedures Electromyography (EMG) Gene therapy Genetic testing Knee braces for osteoarthritis Show more associated procedures Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Products & Services Book: Mayo Clinic Family Health Book, 5th Edition Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Charcot-Marie-Tooth diseaseSymptoms & causesDiagnosis & treatmentDoctors & departments Charcot-Marie-Tooth disease Symptoms & causesDiagnosis & treatmentDoctors & departments",189,Charcot Marie Tooth Disease "Symptoms of persistent depressive disorder can cause major problems in your life and may include: Sadness, emptiness or feeling down. Loss of interest in daily activities. Tiredness and lack of energy. Low self-esteem, self-criticism or feeling you're not capable. Trouble focusing clearly and trouble making decisions. Problems getting things done well and on time. Quickly becoming annoyed, impatient or angry. Avoidance of social activities. Feelings of guilt and worries over the past. Poor appetite or overeating. Sleep problems. Hopelessness. In children, symptoms of persistent depressive disorder may include depressed mood and being irritable, which means easily becoming annoyed, impatient or angry.",747,Persistent Depressive Disorder "Petechiae: Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Here they appear on a leg (A) and on an abdomen (B). Petechiae Petechiae Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae may look like a rash and usually appear in clusters. People with myelodysplastic syndromes might not experience signs and symptoms at first. In time, myelodysplastic syndromes might cause: Fatigue Shortness of breath Unusual paleness (pallor), which occurs due to a low red blood cell count (anemia) Easy or unusual bruising or bleeding, which occurs due to a low blood platelet count (thrombocytopenia) Pinpoint-sized red spots just beneath the skin that are caused by bleeding (petechiae) Frequent infections, which occur due to a low white blood cell count (leukopenia)",660,Myelodysplastic Syndrome "may cause the following signs and symptoms: Obstruction of one or both nostrils. This blockage can make it difficult to breathe through the nostril or nostrils. You may notice this more when you have a cold or allergies that can cause your nasal passages to swell and narrow. Nosebleeds. The surface of your nasal septum may become dry, increasing your risk of nosebleeds. Facial pain. There is some debate about the possible nasal causes of facial pain. A possible cause of one-sided facial pain could be a severe deviated septum in which surfaces within the nose touch and cause pressure. Noisy breathing during sleep. A deviated septum or swelling of the tissues in your nose can be one of the many reasons for noisy breathing during sleep. Awareness of the nasal cycle. The nose alternates between being obstructed on one side and then changes to being obstructed on the other. This is called the nasal cycle. Being aware of the nasal cycle isn't typical and can indicate nasal obstruction. Preference for sleeping on a particular side. Some people may prefer to sleep on a particular side to optimize breathing through the nose at night if one nasal passage is narrowed.",283,Deviated Septum "Signs and symptoms of the condition may include: Pain, particularly in adolescents Swollen breast tissue Breast tenderness Nipple sensitivity with rubbing against clothes",433,Gynecomastia "Signs and symptoms of allergic rhinitis caused by a mold allergy can include: Sneezing Runny or stuffy nose Cough and postnasal drip Itchy eyes, nose and throat Watery eyes Dry, scaly skin Mold allergy symptoms vary from person to person and range from mild to severe. You might have year-round symptoms or symptoms that flare up only during certain times of the year. You might notice symptoms when the weather is damp or when you're in indoor or outdoor spaces that have high concentrations of mold. Mold allergy and asthma If you have a mold allergy and asthma, your asthma symptoms can be triggered by exposure to mold spores. In some people, exposure to certain molds can cause a severe asthma attack. Signs and symptoms of asthma include: Coughing Wheezing Shortness of breath Chest tightness",642,Mold Allergy "There are many different types of: Ehlers-Danlos syndrome, but the most common signs and symptoms include: Overly flexible joints. Because the connective tissue that holds joints together is looser, your joints can move far past the normal range of motion. Joint pain and dislocations are common. Stretchy skin. Weakened connective tissue allows your skin to stretch much more than usual. You may be able to pull a pinch of skin up away from your flesh, but it will snap right back into place when you let go. Your skin might also feel exceptionally soft and velvety. Fragile skin. Damaged skin often doesn't heal well. For example, the stitches used to close a wound often will tear out and leave a gaping scar. These scars may look thin and crinkly. Symptom severity can vary from person to person and depends on the specific type of Ehlers-Danlos syndrome that you have. The most common type is called hypermobile Ehlers-Danlos syndrome. Vascular Ehlers-Danlos syndrome People who have vascular Ehlers-Danlos syndrome often share distinctive facial features of a thin nose, thin upper lip, small earlobes and prominent eyes. They also have thin, translucent skin that bruises very easily. In fair-skinned people, the underlying blood vessels are very visible through the skin. Vascular Ehlers-Danlos syndrome can weaken your heart's largest artery (aorta), as well as the arteries to other regions of your body. A rupture of any of these larger blood vessels can be fatal. The vascular type can also weaken the walls of the uterus or large intestines — which also may rupture. Causes Different types of Ehlers-Danlos syndrome are associated with a variety of genetic causes, some of which are inherited and passed on from parent to child. If you have the most common form, hypermobile Ehlers-Danlos syndrome, there's a 50% chance that you'll pass on the gene to each of your children. Complications Complications depend on the types of signs and symptoms you have. For example, overly flexible joints can result in joint dislocations and early-onset arthritis. Fragile skin may develop prominent scarring. People who have vascular Ehlers-Danlos syndrome are at risk of often fatal ruptures of major blood vessels. Some organs, such as the uterus and intestines, also may rupture. Pregnancy can increase the risk of a rupture in the uterus. Prevention If you have a personal or family history of Ehlers-Danlos syndrome and you're thinking about starting a family, you may benefit from talking to a genetic counselor — a health care professional trained to assess the risk of inherited disorders. Genetic counseling can help you understand the inheritance pattern of the type of Ehlers-Danlos syndrome that affects you and the risks it poses for your children. By Mayo Clinic Staff By Mayo Clinic Staff Ehlers-Danlos syndrome care at Mayo Clinic",333,Ehlers Danlos Syndrome "Muscle cramps occur mostly in leg muscles, most often in the calf. Cramps usually last for seconds to minutes. After the cramp eases, the area might be sore for hours or days.",656,Muscle Cramp "Jock itch usually begins with a reddened area of skin in the crease in the groin. It often spreads to the upper thigh in a half-moon shape. The rash may be ring-shaped and bordered with a line of small blisters. It may burn or feel itchy, and the skin may be flaky or scaly.",545,Jock Itch "Sweat glands: Sweat glands Sweat glands Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Apocrine glands open into the hair follicle, leading to the surface of the skin. Apocrine glands develop in areas with many hair follicles, such as on the scalp, armpits and groin. Eccrine sweat glands are involved in hyperhidrosis, though apocrine glands may play a role as well. Sweat glands Sweat glands Sweat glands Sweat glands Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Sweat glands Sweat glands Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Sweat glands Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Adults usually develop heat rash in skin folds and where clothing rubs against the skin. In infants, the rash is mainly found on the neck, shoulders and chest. It can also show up in the armpits, elbow creases and groin. Types of heat rash The types of heat rash are classified according to how deep the sweat is trapped in the skin. Signs and symptoms for each type vary. The mildest form of heat rash is called miliaria crystallina. It occurs when the opening of the sweat duct on the surface of the skin (sweat pore) is blocked. This form is marked by tiny, clear, fluid-filled bumps that break easily. A type that occurs deeper in the skin is called miliaria rubra. It is sometimes called prickly heat. Signs and symptoms include small, inflamed blister-like bumps and itching or prickling in the affected area. Occasionally, the inflamed bumps of miliaria rubra fill with pus. This form is called miliaria pustulosa. A less common form of heat rash is called miliaria profunda. It affects the deepest layer of the skin (dermis). It causes firm, painful or itchy inflamed bumps that look like goose bumps and may break open.",455,Heat Rash "re standing on a pebble in your shoe A burning pain in the ball of your foot that may radiate into your toes: Tingling or numbness in your toes In addition to these symptoms, you may find that removing your shoe and rubbing your foot often helps to relieve the pain.",648,Mortons Neuroma Some signs and symptoms of soft palate cancer can include the following: Bleeding Difficulty swallowing Difficulty speaking Bad breath Mouth pain Sores in your mouth that won't heal Loose teeth Pain when you swallow Weight loss Ear pain Swelling in your neck that may hurt White patches in your mouth that won't go away,921,Soft Palate Cancer "Dizziness or lightheadedness: Difficulty breathing or shortness of breath, especially during exercise or when lying flat Fatigue",636,Mitral Valve Prolapse "A child having a febrile seizure may: Have a fever higher than 100.4 F (38.0 C) Lose consciousness Shake or jerk the arms and legs Febrile seizures are classified as simple or complex: Simple febrile seizures. This most common type lasts from a few seconds to 15 minutes. Simple febrile seizures do not recur within a 24-hour period and are not specific to one part of the body. Complex febrile seizures. This type lasts longer than 15 minutes, occurs more than once within 24 hours or is confined to one side of your child's body. Febrile seizures most often occur within 24 hours of the onset of a fever and can be the first sign that a child is ill.",370,Febrile Seizure "Pulmonary valve stenosis symptoms depend on how much blood flow is blocked. Some people with mild pulmonary stenosis do not have symptoms. Those with more-severe pulmonary stenosis may first notice symptoms while exercising. Pulmonary valve stenosis symptoms may include: A whooshing sound called a heart murmur that can be heard with a stethoscope. Fatigue. Shortness of breath, especially during activity. Chest pain. Fainting. Babies with pulmonary valve stenosis may have blue or gray skin due to low oxygen levels.",830,Pulmonary Valve Stenosis "Gout: Gout Gout Gout causes intense pain and swelling around one or more joints. Gout most commonly affects the joint at the base of the big toe. Gout Gout Gout Gout Gout causes intense pain and swelling around one or more joints. Gout Gout Gout causes intense pain and swelling around one or more joints. Gout Gout causes intense pain and swelling around one or more joints. Gout causes intense pain and swelling around one or more joints. The signs and symptoms of gout almost always occur suddenly, and often at night. They include: Intense joint pain. Gout usually affects the big toe, but it can occur in any joint. Other commonly affected joints include the ankles, knees, elbows, wrists and fingers. The pain is likely to be most severe within the first four to 12 hours after it begins. Lingering discomfort. After the most severe pain subsides, some joint discomfort may last from a few days to a few weeks. Later attacks are likely to last longer and affect more joints. Inflammation and redness. The affected joint or joints become swollen, tender, warm and red. Limited range of motion. As gout progresses, you may not be able to move your joints normally.",424,Gout "Epididymitis: Epididymitis Epididymitis Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Epididymitis Epididymitis Epididymitis Epididymitis Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Epididymitis Epididymitis Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Epididymitis Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Epididymitis is an inflammation of the coiled tube, called the epididymis, at the back of the testicle. Symptoms of epididymitis might include: A swollen, discolored or warm scrotum Testicle pain and tenderness, usually on one side, that often comes on slowly Pain when you pass urine An urgent or frequent need to urinate Discharge from the penis Pain or discomfort in the lower abdomen or pelvic area Blood in the semen Less commonly, fever Chronic epididymitis Epididymitis that lasts longer than six weeks or that happens over and over again is considered chronic. Symptoms of chronic epididymitis might come on slowly. Sometimes the cause of chronic epididymitis isn't able to be found.",349,Epididymitis "Signs and symptoms of chronic pneumonitis include: Shortness of breath Cough Fatigue Loss of appetite Unintentional weight loss When to call a doctor Call your doctor anytime you have difficulty breathing, no matter what might be the cause.",767,Pneumonitis "Petechiae: Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Here they appear on a leg (A) and on an abdomen (B). Petechiae Petechiae Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae Petechiae may look like a rash and usually appear in clusters. Petechiae may look like a rash and usually appear in clusters. Thrombocytopenia signs and symptoms may include: Easy or excessive bruising (purpura) Superficial bleeding into the skin that appears as a rash of pinpoint-sized reddish-purple spots (petechiae), usually on the lower legs Prolonged bleeding from cuts Bleeding from your gums or nose Blood in urine or stools Unusually heavy menstrual flows Fatigue Enlarged spleen",983,Thrombocytopenia tie include: Difficulty lifting the tongue to the upper teeth or moving the tongue from side to side Trouble sticking out the tongue past the lower front teeth A tongue that appears notched or heart shaped when stuck out,993,Tongue Tie "Acute porphyrias: Acute porphyrias include forms of the disease that typically cause nervous system symptoms, which appear quickly and can be severe. Symptoms may last days to weeks and usually improve slowly after the attack. Acute intermittent porphyria is the common form of acute porphyria. Signs and symptoms of acute porphyria may include: Severe abdominal pain Pain in your chest, legs or back Constipation or diarrhea Nausea and vomiting Muscle pain, tingling, numbness, weakness or paralysis Red or brown urine Mental changes, such as anxiety, confusion, hallucinations, disorientation or paranoia Breathing problems Urination problems Rapid or irregular heartbeats you can feel (palpitations) High blood pressure Seizures Cutaneous porphyrias Cutaneous porphyrias include forms of the disease that cause skin symptoms as a result of sensitivity to sunlight, but these forms don't usually affect your nervous system. Porphyria cutanea tarda (PCT) is the most common type of all the porphyrias. As a result of sun exposure, you may experience: Sensitivity to the sun and sometimes artificial light, causing burning pain Sudden painful skin redness (erythema) and swelling (edema Blisters on exposed skin, usually the hands, arms and face Fragile thin skin with changes in skin color (pigment) Itching Excessive hair growth in affected areas Red or brown urine",780,Porphyria "Digestive signs and symptoms for adults include: Diarrhea Fatigue Weight loss Bloating and gas Abdominal pain Nausea and vomiting Constipation However, more than half the adults with celiac disease have signs and symptoms unrelated to the digestive system, including: Anemia, usually from iron deficiency Loss of bone density (osteoporosis) or softening of bone (osteomalacia) Itchy, blistery skin rash (dermatitis herpetiformis) Mouth ulcers Headaches and fatigue Nervous system injury, including numbness and tingling in the feet and hands, possible problems with balance, and cognitive impairment Joint pain Reduced functioning of the spleen (hyposplenism) Children Children with celiac disease are more likely than adults to have digestive problems, including: Nausea and vomiting Chronic diarrhea Swollen belly Constipation Gas Pale, foul-smelling stools The inability to absorb nutrients might result in: Failure to thrive for infants Damage to tooth enamel Weight loss Anemia Irritability Short stature Delayed puberty Neurological symptoms, including attention-deficit/hyperactivity disorder (ADHD), learning disabilities, headaches, lack of muscle coordination and seizures Dermatitis herpetiformis Gluten intolerance can cause this itchy, blistering skin disease. The rash usually occurs on the elbows, knees, torso, scalp and buttocks. This condition is often associated with changes to the lining of the small intestine identical to those of celiac disease, but the skin condition might not cause digestive symptoms. Doctors treat dermatitis herpetiformis with a gluten-free diet or medication, or both, to control the rash.",179,Celiac Disease "Bulimia signs and symptoms may include: Being preoccupied with your body shape and weight Living in fear of gaining weight Repeated episodes of eating abnormally large amounts of food in one sitting Feeling a loss of control during bingeing — like you can't stop eating or can't control what you eat Forcing yourself to vomit or exercising too much to keep from gaining weight after bingeing Using laxatives, diuretics or enemas after eating when they're not needed Fasting, restricting calories or avoiding certain foods between binges Using dietary supplements or herbal products excessively for weight loss The severity of bulimia is determined by the number of times a week that you purge, usually at least once a week for at least three months.",156,Bulimia "s diarrhea are: Abrupt onset of passage of three or more looser watery stools a day An urgent need to defecate Abdominal cramps Nausea Vomiting Fever Sometimes, people experience moderate to severe dehydration, persistent vomiting, a high fever, bloody stools, or severe pain in the abdomen or rectum. If you or your child experiences any of these signs or symptoms or if the diarrhea lasts longer than a few days, it's time to see a doctor.",1009,Travelers Diarrhea "you might experience these signs and symptoms: Irregular periods Vaginal dryness Hot flashes Chills Night sweats Sleep problems Mood changes Weight gain and slowed metabolism Thinning hair and dry skin Loss of breast fullness Signs and symptoms, including changes in menstruation can vary among women. Most likely, you'll experience some irregularity in your periods before they end. Skipping periods during perimenopause is common and expected. Often, menstrual periods will skip a month and return, or skip several months and then start monthly cycles again for a few months. Periods also tend to happen on shorter cycles, so they are closer together. Despite irregular periods, pregnancy is possible. If you've skipped a period but aren't sure you've started the menopausal transition, consider a pregnancy test.",615,Menopause Signs and symptoms include: Agitation or restlessness Insomnia Confusion Rapid heart rate and high blood pressure Dilated pupils Loss of muscle coordination or twitching muscles High blood pressure Muscle rigidity Heavy sweating Diarrhea Headache Shivering Goose bumps Severe serotonin syndrome can be life-threatening. Signs include: High fever Tremor Seizures Irregular heartbeat Unconsciousness,897,Serotonin Syndrome "Leukoplakia may appear: White or grayish in patches that can't be wiped away Irregular or flat-textured Thickened or hardened in areas Along with raised, red lesions (speckled leukoplakia or erythroplakia), which are more likely to show precancerous changes Hairy leukoplakia Hairy leukoplakia causes fuzzy, white patches that resemble folds or ridges, usually on the sides of your tongue. It's often mistaken for oral thrush, an infection marked by creamy white patches that can be wiped away, which is also common in people with a weakened immune system. When to see a doctor Even though leukoplakia doesn't usually cause discomfort, sometimes it can indicate a more serious condition. See your dentist or primary care professional if you have any of the following: White plaques or sores in your mouth that don't heal on their own within two weeks Lumps or white, red or dark patches in your mouth Persistent changes in the tissues of your mouth Ear pain when swallowing Progressive reduction in the ability to open your jaw",572,Leukoplakia "The main symptom of hyperhidrosis is heavy sweating. This goes beyond the sweating from being in a hot environment, exercising, or feeling anxious or stressed. The type of hyperhidrosis that usually affects the hands, feet, underarms or face causes at least one episode a week when you're awake. And the sweating usually happens on both sides of the body.",497,Hyperhidrosis "specific symptoms of polycythemia vera include: Itchiness, especially after a warm bath or shower Numbness, tingling, burning, or weakness in your hands, feet, arms or legs A feeling of fullness soon after eating and bloating or pain in your left upper abdomen due to an enlarged spleen Unusual bleeding, such as a nosebleed or bleeding gums Painful swelling of one joint, often the big toe Shortness of breath and difficulty breathing when lying down",772,Polycythemia Vera "but common signs and symptoms include: Cognitive changes Memory loss, which is usually noticed by someone else Difficulty communicating or finding words Difficulty with visual and spatial abilities, such as getting lost while driving Difficulty reasoning or problem-solving Difficulty handling complex tasks Difficulty with planning and organizing Difficulty with coordination and motor functions Confusion and disorientation Psychological changes Personality changes Depression Anxiety Inappropriate behavior Paranoia Agitation Hallucinations",274,Dementia "Contact dermatitis on the face: Contact dermatitis on the face Contact dermatitis on the face Contact dermatitis often affects skin directly exposed to an offending substance. Here, the rash is likely caused by cosmetics. Contact dermatitis on the face Contact dermatitis on the face Contact dermatitis on the face Contact dermatitis on the face Contact dermatitis often affects skin directly exposed to an offending substance. Contact dermatitis on the face Contact dermatitis on the face Contact dermatitis often affects skin directly exposed to an offending substance. Contact dermatitis on the face Contact dermatitis often affects skin directly exposed to an offending substance. Contact dermatitis often affects skin directly exposed to an offending substance. Poison ivy blisters Poison ivy blisters Poison ivy blisters Here, the blisters are caused by contact with the oily substance in poison ivy (urushiol) that causes allergic reactions. Poison ivy blisters Poison ivy blisters Poison ivy blisters Poison ivy blisters Here, the blisters are caused by contact with the oily substance in poison ivy (urushiol) that causes allergic reactions. Poison ivy blisters Poison ivy blisters Here, the blisters are caused by contact with the oily substance in poison ivy (urushiol) that causes allergic reactions. Poison ivy blisters Here, the blisters are caused by contact with the oily substance in poison ivy (urushiol) that causes allergic reactions. Here, the blisters are caused by contact with the oily substance in poison ivy (urushiol) that causes allergic reactions. Contact dermatitis shows up on skin that has been directly exposed to the substance causing the reaction. For example, the rash may show up along a leg that brushed against poison ivy. The rash can develop within minutes to hours of exposure, and it can last 2 to 4 weeks. Signs and symptoms of contact dermatitis vary widely and may include: An itchy rash Leathery patches that are darker than usual (hyperpigmented), typically on brown or Black skin Dry, cracked, scaly skin, typically on white skin Bumps and blisters, sometimes with oozing and crusting Swelling, burning or tenderness",246,Contact Dermatitis "The symptoms of a coma commonly include: Closed eyes. Depressed brainstem reflexes, such as pupils not responding to light. No responses of limbs except for reflex movements. No response to painful stimuli except for reflex movements. Irregular breathing.",233,Coma "Signs and symptoms of a ruptured spleen include: Pain in the upper left abdomen Tenderness when you touch the upper left abdomen Left shoulder pain Confusion, lightheadedness or dizziness",870,Ruptured Spleen "preeclampsia signs and symptoms may include: Excess protein in urine (proteinuria) or other signs of kidney problems Decreased levels of platelets in blood (thrombocytopenia) Increased liver enzymes that indicate liver problems Severe headaches Changes in vision, including temporary loss of vision, blurred vision or light sensitivity Shortness of breath, caused by fluid in the lungs Pain in the upper belly, usually under the ribs on the right side Nausea or vomiting Weight gain and swelling (edema) are typical during healthy pregnancies. However, sudden weight gain or a sudden appearance of edema — particularly in your face and hands — may be a sign of preeclampsia.",793,Preeclampsia "Behavioral changes: The most common signs of frontotemporal dementia involve extreme changes in behavior and personality. These include: Increasingly inappropriate social behavior Loss of empathy and other interpersonal skills, such as having sensitivity to another's feelings Lack of judgment Loss of inhibition Lack of interest (apathy), which can be mistaken for depression Repetitive compulsive behavior, such as tapping, clapping or smacking lips A decline in personal hygiene Changes in eating habits, usually overeating or developing a preference for sweets and carbohydrates Eating inedible objects Compulsively wanting to put things in the mouth Speech and language problems Some subtypes of frontotemporal dementia lead to language problems or impairment or loss of speech. Primary progressive aphasia, semantic dementia and progressive agrammatic (nonfluent) aphasia are all considered to be frontotemporal dementia. Problems caused by these conditions include: Increasing difficulty in using and understanding written and spoken language, such as having trouble finding the right word to use in speech or naming objects Trouble naming things, possibly replacing a specific word with a more general word such as ""it"" for pen No longer knowing word meanings Having hesitant speech that may sound telegraphic Making mistakes in sentence construction Motor disorders Rarer subtypes of frontotemporal dementia are characterized by problems with movement similar to those associated with Parkinson's disease or amyotrophic lateral sclerosis (ALS). Motor-related problems may include: Tremor Rigidity Muscle spasms or twitches Poor coordination Difficulty swallowing Muscle weakness Inappropriate laughing or crying Falls or walking problems Causes In frontotemporal dementia, the frontal and temporal lobes of the brain shrink. In addition, certain substances accumulate in the brain. What causes these changes is usually unknown. There are genetic mutations that have been linked to frontotemporal dementia. But more than half of the people who develop frontotemporal dementia have no family history of dementia. Recently, researchers have confirmed shared genetics and molecular pathways between frontotemporal dementia and amyotrophic lateral sclerosis (ALS). More research needs to be done to understand the connection between these conditions, however. Risk factors Your risk of developing frontotemporal dementia is higher if you have a family history of dementia. There are no other known risk factors. By Mayo Clinic Staff By Mayo Clinic Staff Frontotemporal dementia care at Mayo Clinic",389,Frontotemporal Dementia "The pain may: Spread to the left shoulder and neck Get worse when coughing, lying down or taking a deep breath Get better when sitting up or leaning forward Other signs and symptoms of pericarditis may include: Cough Fatigue or general feeling of weakness or being sick Leg swelling Low-grade fever Pounding or racing heartbeat (heart palpitations) Shortness of breath when lying down Swelling of the belly (abdomen) The specific symptoms depend on the type of pericarditis. Pericarditis is grouped into different categories, according to the pattern of symptoms and how long symptoms last. Acute pericarditis begins suddenly but doesn't last longer than three weeks. Future episodes can occur. It may be difficult to tell the difference between acute pericarditis and pain due to a heart attack. Recurrent pericarditis occurs about four to six weeks after an episode of acute pericarditis with no symptoms in between. Incessant pericarditis lasts about four to six weeks but less than three months. The symptoms are continuous. Chronic constrictive pericarditis usually develops slowly and lasts longer than three months.",738,Pericarditis "Egg allergy symptoms can include: Skin inflammation or hives — the most common egg allergy reaction Nasal congestion, runny nose and sneezing (allergic rhinitis) Digestive symptoms, such as cramps, nausea and vomiting Asthma signs and symptoms such as coughing, wheezing, chest tightness or shortness of breath Anaphylaxis A severe allergic reaction can lead to anaphylaxis, a life-threatening emergency that requires an immediate epinephrine (adrenaline) shot and a trip to the emergency room. Anaphylaxis signs and symptoms include: Constriction of airways, including a swollen throat or a lump in your throat that makes it difficult to breathe Abdominal pain and cramping Rapid pulse Shock, with a severe drop in blood pressure felt as dizziness, lightheadedness or loss of consciousness Discuss with your doctor any reaction — no matter how mild — you or your child has to eggs. The severity of egg allergy reactions can vary each time one occurs, so even if a past reaction was mild, the next one could be more serious. If your doctor thinks you or your child may be at risk of a severe reaction, he or she may prescribe an emergency epinephrine shot to be used if anaphylaxis occurs. The shot comes in a device that makes it easy to deliver, called an autoinjector.",332,Egg Allergy "Orchitis signs and symptoms usually develop suddenly and can include: Swelling in one or both testicles Pain ranging from mild to severe Fever Nausea and vomiting General feeling of unwellness (malaise) The terms ""testicle pain"" and ""groin pain"" are sometimes used interchangeably. But groin pain occurs in the fold of skin between the thigh and abdomen — not in the testicle. The causes of groin pain are different from the causes of testicle pain.",698,Orchitis "pylori: When signs or symptoms do occur with H. pylori infection, they are typically related to gastritis or a peptic ulcer and may include: H. pylori An ache or burning pain in your stomach (abdomen) Stomach pain that may be worse when your stomach is empty Nausea Loss of appetite Frequent burping Bloating Unintentional weight loss",434,H Pylori "Many people with unicentric: Castleman disease don't notice any signs or symptoms. The enlarged lymph node may be found during a physical exam or an imaging test for some unrelated problem. Some people with unicentric Castleman disease might have signs and symptoms that are more commonly seen in multicentric Castleman disease, which may include: Fever. Unintended weight loss. Fatigue. Night sweats. Enlarged liver or spleen. The enlarged lymph nodes associated with multicentric Castleman disease are most commonly found in the neck, collarbone, underarm and groin areas.",175,Castleman Disease "XLA: Male infants born with XLA have: XLA Very small tonsils Small or no lymph nodes Causes X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier. X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. X-linked inheritance pattern with carrier mother X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. X-linked agammaglobulinemia is caused by a genetic mutation. People with the condition can't produce antibodies that fight infection. About 40% of people with the condition have a family member who has it. Complications People with XLA can live relatively normal lives and should be encouraged to participate in regular activities for their ages. However, recurrent infections related to XLA will likely require careful attention and aggressive treatment. They can cause organ damage and be life-threatening. XLA XLA Possible complications include: Chronic lung disease Increased risk of certain cancers Infectious arthritis Increased risk of central nervous system infections from live vaccines By Mayo Clinic Staff By Mayo Clinic Staff X-linked agammaglobulinemia care at Mayo Clinic",1077,X Linked Agammaglobulinemia "Cluster A personality disorders: Cluster A personality disorders are characterized by odd, eccentric thinking or behavior. They include paranoid personality disorder, schizoid personality disorder and schizotypal personality disorder. Paranoid personality disorder Pervasive distrust and suspicion of others and their motives Unjustified belief that others are trying to harm or deceive you Unjustified suspicion of the loyalty or trustworthiness of others Hesitancy to confide in others due to unreasonable fear that others will use the information against you Perception of innocent remarks or nonthreatening situations as personal insults or attacks Angry or hostile reaction to perceived slights or insults Tendency to hold grudges Unjustified, recurrent suspicion that spouse or sexual partner is unfaithful Schizoid personality disorder Lack of interest in social or personal relationships, preferring to be alone Limited range of emotional expression Inability to take pleasure in most activities Inability to pick up normal social cues Appearance of being cold or indifferent to others Little or no interest in having sex with another person Schizotypal personality disorder Peculiar dress, thinking, beliefs, speech or behavior Odd perceptual experiences, such as hearing a voice whisper your name Flat emotions or inappropriate emotional responses Social anxiety and a lack of or discomfort with close relationships Indifferent, inappropriate or suspicious response to others ""Magical thinking"" — believing you can influence people and events with your thoughts Belief that certain casual incidents or events have hidden messages meant only for you Cluster B personality disorders Cluster B personality disorders are characterized by dramatic, overly emotional or unpredictable thinking or behavior. They include antisocial personality disorder, borderline personality disorder, histrionic personality disorder and narcissistic personality disorder. Antisocial personality disorder Disregard for others' needs or feelings Persistent lying, stealing, using aliases, conning others Recurring problems with the law Repeated violation of the rights of others Aggressive, often violent behavior Disregard for the safety of self or others Impulsive behavior Consistently irresponsible Lack of remorse for behavior Borderline personality disorder Impulsive and risky behavior, such as having unsafe sex, gambling or binge eating Unstable or fragile self-image Unstable and intense relationships Up and down moods, often as a reaction to interpersonal stress Suicidal behavior or threats of self-injury Intense fear of being alone or abandoned Ongoing feelings of emptiness Frequent, intense displays of anger Stress-related paranoia that comes and goes Histrionic personality disorder Constantly seeking attention Excessively emotional, dramatic or sexually provocative to gain attention Speaks dramatically with strong opinions, but few facts or details to back them up Easily influenced by others Shallow, rapidly changing emotions Excessive concern with physical appearance Thinks relationships with others are closer than they really are Narcissistic personality disorder Belief that you're special and more important than others Fantasies about power, success and attractiveness Failure to recognize others' needs and feelings Exaggeration of achievements or talents Expectation of constant praise and admiration Arrogance Unreasonable expectations of favors and advantages, often taking advantage of others Envy of others or belief that others envy you Cluster C personality disorders Cluster C personality disorders are characterized by anxious, fearful thinking or behavior. They include avoidant personality disorder, dependent personality disorder and obsessive-compulsive personality disorder. Avoidant personality disorder Too sensitive to criticism or rejection Feeling inadequate, inferior or unattractive Avoidance of work activities that require interpersonal contact Socially inhibited, timid and isolated, avoiding new activities or meeting strangers Extreme shyness in social situations and personal relationships Fear of disapproval, embarrassment or ridicule Dependent personality disorder Excessive dependence on others and feeling the need to be taken care of Submissive or clingy behavior toward others Fear of having to provide self-care or fend for yourself if left alone Lack of self-confidence, requiring excessive advice and reassurance from others to make even small decisions Difficulty starting or doing projects on your own due to lack of self-confidence Difficulty disagreeing with others, fearing disapproval Tolerance of poor or abusive treatment, even when other options are available Urgent need to start a new relationship when a close one has ended Obsessive-compulsive personality disorder Preoccupation with details, orderliness and rules Extreme perfectionism, resulting in dysfunction and distress when perfection is not achieved, such as feeling unable to finish a project because you don't meet your own strict standards Desire to be in control of people, tasks and situations, and inability to delegate tasks Neglect of friends and enjoyable activities because of excessive commitment to work or a project Inability to discard broken or worthless objects Rigid and stubborn Inflexible about morality, ethics or values Tight, miserly control over budgeting and spending money Obsessive-compulsive personality disorder is not the same as obsessive-compulsive disorder, a type of anxiety disorder. When to see a doctor If you have any signs or symptoms of a personality disorder, see your doctor or other primary care professional or a mental health professional. Untreated, personality disorders can cause significant problems in your life that may get worse without treatment.",748,Personality Disorders "The muscle weakness associated with polymyositis involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen.",776,Polymyositis such as when someone takes a flash photograph of the child: Eyes that appear to be looking in different directions Poor vision Eye redness Eye swelling,852,Retinoblastoma "Lewy body dementia signs and symptoms can include: Visual hallucinations. Hallucinations — seeing things that aren't there — might be one of the first symptoms, and they often recur. People with Lewy body dementia might hallucinate shapes, animals or people. Sound (auditory), smell (olfactory) or touch (tactile) hallucinations are possible. Movement disorders. Signs of Parkinson's disease (parkinsonian signs), such as slowed movement, rigid muscles, tremor or a shuffling walk can occur. This can lead to falling. Poor regulation of body functions (autonomic nervous system). Blood pressure, pulse, sweating and the digestive process are regulated by a part of the nervous system that is often affected by Lewy body dementia. This can result in sudden drops in blood pressure upon standing (orthostatic hypotension), dizziness, falls, loss of bladder control (urinary incontinence) and bowel issues such as constipation. Cognitive problems. You might have thinking (cognitive) problems similar to those of Alzheimer's disease, such as confusion, poor attention, visual-spatial problems and memory loss. Sleep difficulties. You might have rapid eye movement (REM) sleep behavior disorder, which can cause you to physically act out your dreams while you're asleep. This might involve behavior such as punching, kicking, yelling and screaming while sleeping. Fluctuating attention. Episodes of drowsiness, long periods of staring into space, long naps during the day or disorganized speech are possible. Depression. You might develop depression. Apathy. You might lose motivation.",573,Lewy Body Dementia "They may include: Visual distortions, such as straight lines seeming bent. Reduced central vision in one or both eyes. The need for brighter light when reading or doing close-up work. Difficulty adjusting to low light levels, such as when entering a dimly lit restaurant or theater. Increased blurriness of printed words. Difficulty recognizing faces. A well-defined blurry spot or blind spot in the field of vision. Macular degeneration doesn't affect side vision, so it doesn't cause total blindness.",1066,Wet Macular Degeneration "gray membrane covering the throat and tonsils A sore throat and hoarseness: Swollen glands (enlarged lymph nodes) in the neck Difficulty breathing or rapid breathing Nasal discharge Fever and chills Tiredness In some people, infection with diphtheria-causing bacteria causes only a mild illness — or no obvious signs and symptoms at all. Infected people who stay unaware of their illness are known as carriers of diphtheria. They're called carriers because they can spread the infection without being sick themselves. Skin (cutaneous) diphtheria A second type of diphtheria can affect the skin, causing pain, redness and swelling similar to other bacterial skin infections. Ulcers covered by a gray membrane also may be a sign of skin diphtheria. Although it's more common in tropical climates, diphtheria on the skin also occurs in the United States. It may happen especially among people with poor hygiene who live in crowded conditions.",298,Diphtheria "Signs and symptoms of a broken leg may include: Severe pain, which may worsen with movement Swelling Tenderness Bruising Obvious deformity or shortening of the affected leg Inability to walk Toddlers or young children who break a leg may start limping or simply stop walking, even if they can't explain why.",144,Broken Leg "Common signs and symptoms of head lice may include: Itching. The most common symptom of head lice is itching on the scalp, neck and ears. This is an allergic reaction to louse bites. When a person has head lice for the first time, itching may not occur for 4 to 6 weeks. Lice on scalp. You may be able to see the lice, but they're often hard to spot because they're small, avoid light and move quickly. Lice eggs (nits) on hair shafts. Nits stick to hair shafts and may be hard to see because they're very tiny. They're easiest to spot around the ears and the hairline of the neck. Empty nits may be easier to spot because they're lighter in color and further from the scalp. However, the presence of nits doesn't mean there are live lice. Sores on the scalp, neck and shoulders. Scratching can lead to small, red bumps that may sometimes get infected with bacteria.",443,Head Lice Elevated blood pressure doesn't cause symptoms. The only way to detect it is to have regular blood pressure checks. Have your blood pressure measured when you visit your health care provider. You can also check it at home with a home blood pressure monitoring device.,795,Prehypertension "They include: Feeling bloated or too full after eating Nausea Vomiting Abdominal cramps Diarrhea Flushing Dizziness, lightheadedness Rapid heart rate Late dumping syndrome starts 1 to 3 hours after you eat a high-sugar meal. It takes time for signs and symptoms to develop because after you eat your body releases large amounts of insulin to absorb the sugars entering your small intestine. The result is low blood sugar. Signs and symptoms of late dumping syndrome can include: Sweating Flushing Dizziness, lightheadedness Weakness Rapid heart rate Some people have both early and late signs and symptoms. And dumping syndrome can develop years after surgery.",315,Dumping Syndrome "Vertebral tumor signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of your body Back pain that's worse at night Loss of sensation or muscle weakness, especially in your arms or legs Difficulty walking, sometimes leading to falls Feeling less sensitive to cold, heat and pain Loss of bowel or bladder function Paralysis, which may be mild or severe, and can strike in different areas throughout the body Spinal tumors progress at different rates depending on the type of tumor.",1054,Vertebral Tumor "Other signs and symptoms might include: Swelling, stiffness and tenderness at the base of your thumb Decreased strength when pinching or grasping objects Decreased range of motion Enlarged or bony appearance of the joint at the base of your thumb",985,Thumb Arthritis "Eye muscles: In more than half of people who develop myasthenia gravis, their first signs and symptoms involve eye problems, such as: Drooping of one or both eyelids (ptosis) Double vision (diplopia), which may be horizontal or vertical, and improves or resolves when one eye is closed Face and throat muscles In about 15% of people with myasthenia gravis, the first symptoms involve face and throat muscles, which can: Impair speaking. Your speech might sound soft or nasal, depending on which muscles have been affected. Cause difficulty swallowing. You might choke easily, making it difficult to eat, drink or take pills. In some cases, liquids you're trying to swallow come out your nose. Affect chewing. The muscles used for chewing might tire halfway through a meal, particularly if you've been eating something hard to chew, such as steak. Change facial expressions. For example, your smile might look like a snarl. Neck and limb muscles Myasthenia gravis can also cause weakness in your neck, arms and legs. Weakness in your legs can affect how you walk. Weak neck muscles make it hard to hold up your head.",659,Myasthenia Gravis "especially if you cough or strain A burning or aching sensation at the bulge: Pain or discomfort in your groin, especially when bending over, coughing or lifting A heavy or dragging sensation in your groin Weakness or pressure in your groin Occasionally, pain and swelling around the testicles when the protruding intestine descends into the scrotum Signs and symptoms in children Inguinal hernias in newborns and children result from a weakness in the abdominal wall that's present at birth. Sometimes the hernia will be visible only when an infant is crying, coughing or straining during a bowel movement. He or she might be irritable and have less appetite than usual. In an older child, a hernia is likely to be more apparent when the child coughs, strains during a bowel movement or stands for a long period. Signs of trouble If you aren't able to push the hernia in, the contents of the hernia may be trapped (incarcerated) in the abdominal wall. An incarcerated hernia can become strangulated, which cuts off the blood flow to the tissue that's trapped. A strangulated hernia can be life-threatening if it isn't treated. Signs and symptoms of a strangulated hernia include: Nausea, vomiting or both Fever Sudden pain that quickly intensifies A hernia bulge that turns red, purple or dark Inability to move your bowels or pass gas",526,Inguinal Hernia "among others: Delusions — having false, fixed beliefs, despite evidence to the contrary Hallucinations, such as hearing voices or seeing things that aren't there Impaired communication and speech, such as being incoherent Bizarre or unusual behavior Symptoms of depression, such as feeling empty, sad or worthless Periods of manic mood, with an increase in energy and a decreased need for sleep over several days, and behaviors that are out of character Impaired occupational, academic and social functioning Problems with managing personal care, including cleanliness and physical appearance",880,Schizoaffective Disorder "Signs and symptoms of a tooth abscess include: Severe, constant, throbbing toothache that can spread to your jawbone, neck or ear Pain or discomfort with hot and cold temperatures Pain or discomfort with the pressure of chewing or biting Fever Swelling in your face, cheek or neck that may lead to difficulty breathing or swallowing Tender, swollen lymph nodes under your jaw or in your neck Foul odor in your mouth Sudden rush of foul-smelling and foul-tasting, salty fluid in your mouth and pain relief, if the abscess ruptures",996,Tooth Abscess "Vitiligo signs include: Patchy loss of skin color, which usually first appears on the hands, face, and areas around body openings and the genitals Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard Loss of color in the tissues that line the inside of the mouth and nose (mucous membranes) Vitiligo can start at any age, but usually appears before age 30. Depending on the type of vitiligo you have, it may affect: Nearly all skin surfaces. With this type, called universal vitiligo, the discoloration affects nearly all skin surfaces. Many parts of the body. With this most common type, called generalized vitiligo, the discolored patches often progress similarly on corresponding body parts (symmetrically). Only one side or part of the body. This type, called segmental vitiligo, tends to occur at a younger age, progress for a year or two, then stop. One or only a few areas of the body. This type is called localized (focal) vitiligo. The face and hands. With this type, called acrofacial vitiligo, the affected skin is on the face and hands, and around body openings, such as the eyes, nose and ears. It's difficult to predict how this disease will progress. Sometimes the patches stop forming without treatment. In most cases, pigment loss spreads and eventually involves most of the skin. Occasionally, the skin gets its color back.",1060,Vitiligo "For most people with pseudocholinesterase deficiency, no signs or symptoms of the condition occur until you get the muscle relaxant succinylcholine. This medication is used as part of anesthesia. Signs and symptoms of pseudocholinesterase deficiency include muscle relaxation or muscle paralysis that lasts several hours longer than expected. During that time, you can't move or breathe on your own. The length of time may vary widely among people with this disorder.",818,Pseudocholinesterase Deficiency "A popping sensation: Swelling or stiffness Pain, especially when twisting or rotating your knee Difficulty straightening your knee fully Feeling as though your knee is locked in place when you try to move it Feeling of your knee giving way",997,Torn Meniscus "Signs and symptoms of: Turner syndrome may vary among girls and women with the disorder. For some girls, the presence of Turner syndrome may not be readily apparent, but in other girls, several physical features are apparent early. Signs and symptoms can be subtle, developing slowly over time, or significant, such as heart defects. Before birth Turner syndrome may be suspected prenatally based on prenatal cell-free DNA screening ― a method to screen for certain chromosomal abnormalities in a developing baby using a blood sample from the mother ― or prenatal ultrasound. Prenatal ultrasound of a baby with Turner syndrome may show: Large fluid collection on the back of the neck or other abnormal fluid collections (edema) Heart abnormalities Abnormal kidneys At birth or during infancy Signs of Turner syndrome at birth or during infancy may include: Wide or weblike neck Low-set ears Broad chest with widely spaced nipples High, narrow roof of the mouth (palate) Arms that turn outward at the elbows Fingernails and toenails that are narrow and turned upward Swelling of the hands and feet, especially at birth Slightly smaller than average height at birth Slowed growth Cardiac defects Low hairline at the back of the head Receding or small lower jaw Short fingers and toes In childhood, teens and adulthood The most common signs in almost all girls, teenagers and young women with Turner syndrome are short stature and ovarian insufficiency due to ovarian failure. Failure of the ovaries to develop may occur at birth or gradually during childhood, the teen years or young adulthood. Signs and symptoms of these include: Slowed growth No growth spurts at expected times in childhood Adult height significantly less than might be expected for a female member of the family Failure to begin sexual changes expected during puberty Sexual development that ""stalls"" during teenage years Early end to menstrual cycles not due to pregnancy For most females with Turner syndrome, inability to conceive a child without fertility treatment",1021,Turner Syndrome "Symptoms of antisocial personality disorder include repeatedly: Ignoring right and wrong. Telling lies to take advantage of others. Not being sensitive to or respectful of others. Using charm or wit to manipulate others for personal gain or pleasure. Having a sense of superiority and being extremely opinionated. Having problems with the law, including criminal behavior. Being hostile, aggressive, violent or threatening to others. Feeling no guilt about harming others. Doing dangerous things with no regard for the safety of self or others. Being irresponsible and failing to fulfill work or financial responsibilities. Adults with antisocial personality disorder usually show symptoms of conduct disorder before the age of 15. Symptoms of conduct disorder include serious, ongoing behavior problems, such as: Aggression toward people and animals. Destruction of property. Lying and dishonesty. Theft. Serious violation of rules. Antisocial personality disorder is considered a lifelong condition. But in some people, certain symptoms ― particularly destructive and criminal behavior ― may decrease over time. It's not clear whether this decrease is a result of the effect aging has on their mind and body, an increased awareness of the impact that antisocial behavior has had on their life, or other factors.",60,Antisocial Personality Disorder "adenomyosis can cause: Heavy or prolonged menstrual bleeding Severe cramping or sharp, knifelike pelvic pain during menstruation (dysmenorrhea) Chronic pelvic pain Painful intercourse (dyspareunia) Your uterus might get bigger. Although you might not know if your uterus is bigger, you may notice tenderness or pressure in your lower abdomen.",18,Adenomyosis "Female reproductive system: Female reproductive system Female reproductive system The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. Female reproductive system Female reproductive system Female reproductive system Female reproductive system The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. Female reproductive system Female reproductive system The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. Female reproductive system The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. The ovaries, fallopian tubes, uterus, cervix and vagina, also called the vaginal canal, make up the female reproductive system. When ovarian cancer first develops, it might not cause any noticeable symptoms. When ovarian cancer symptoms happen, they're usually attributed to other, more common conditions. Signs and symptoms of ovarian cancer may include: Abdominal bloating or swelling Quickly feeling full when eating Weight loss Discomfort in the pelvic area Fatigue Back pain Changes in bowel habits, such as constipation A frequent need to urinate",706,Ovarian Cancer "BEEC: Epispadias. This is the least severe form of BEEC, in which the tube to expel urine (urethra) doesn't fully develop. Bladder exstrophy. This defect causes the bladder to form on the outside of the body. The bladder is also turned inside out. Usually, bladder exstrophy will involve organs of the urinary tract, as well as the digestive and reproductive systems. Defects of the abdominal wall, bladder, genitals, pelvic bones, final section of the large intestine (rectum) and opening at the end of the rectum (anus) can occur. Children with bladder exstrophy also have vesicoureteral reflux. This condition causes urine to flow the wrong way — from the bladder back up into the tubes that connect to the kidneys (ureters). Children with bladder exstrophy also have epispadias. Cloacal exstrophy. Cloacal exstrophy (kloe-A-kul EK-stroh-fee) is the most serious form of BEEC. In this condition, the rectum, bladder and genitals don't fully separate as the fetus develops. These organs may not be correctly formed, and the pelvic bones are affected as well. The kidneys, backbone and spinal cord also may be affected. Most children with cloacal exstrophy have spinal abnormalities, including spina bifida. Children born with protruding abdominal organs probably also have cloacal exstrophy or bladder exstrophy.",114,Bladder Exstrophy "Infants: Most babies born to women carrying group B strep are healthy. But the few who are infected by group B strep during labor can become critically ill. In infants, illness caused by group B strep can be within six hours of birth (early onset) — or weeks or months after birth (late onset). Signs and symptoms might include: Fever Low body temperature Difficulty feeding Sluggishness, limpness or weak muscle tone Difficulty breathing Irritability Jitteriness Seizures Rash Jaundice Adults Many adults carry group B strep in their bodies — usually in the bowel, vagina, rectum, bladder or throat — and have no signs or symptoms. In some cases, however, group B strep can cause a urinary tract infection or other more-serious infections. Signs and symptoms of infections that may be caused by group B strep include the following. Urinary tract infection A strong, persistent urge to urinate A burning sensation or pain when urinating Passing frequent, small amounts of urine Urine that appears red, bright pink or cola colored — a sign of blood in the urine Pelvic pain Blood infection (bacteremia) Fever Chills Confusion or lack of alertness Pneumonia Fever Chills Cough Shortness of breath Chest pain when you breathe or cough Skin or soft-tissue infection Swelling, warmth or redness in the area of the infection Pain in the area of the infection Lesions with pus or drainage Bone or joint infection Fever Chills Swelling, warmth or redness over the area of the infection Pain in the area of the infection Stiffness or inability to use a limb or joint",430,Group B Strep "shapes and sizes: Color and texture. Moles can be brown, tan, black, blue, red or pink. They can be smooth, wrinkled, flat or raised. They may have hair growing from them. Shape. Most moles are oval or round. Size. Moles are usually less than 1/4 inch (about 6 millimeters) in diameter — the size of a pencil eraser. Those present at birth (congenital nevi) can be bigger than usual, covering part of the face, torso or a limb. Moles can develop anywhere on your body, including your scalp, armpits, under your nails, and between your fingers and toes. Most people have 10 to 40 moles. Many of these develop by age 50. Moles may change or fade away over time. With hormonal changes in adolescence and pregnancy, they may become darker and larger. Clusters of brown spots around the eyes, cheeks and nose are sometimes called flesh moles, but they are actually dermatoses papulosa nigra — a type of seborrheic keratosis, not clusters of pigment-forming cells (nevi). Dermatoses papulosa nigra are more common among Black women. Flesh moles don't carry a risk of melanoma, but they can be treated if you consider them a cosmetic concern. Unusual moles that may indicate melanoma A mole may be a sign of skin cancer if it has irregular borders or an asymmetrical shape or if it changes in color, shape, size or height. This ABCDE guide can help you remember what to watch for: ABCDE A is for asymmetrical shape. One half is unlike the other half. B is for border. Look for moles with irregular, notched or scalloped borders. C is for color. Look for growths that have changed color, have many colors or have uneven color. D is for diameter. Look for new growth in a mole larger than 1/4 inch (about 6 millimeters). E is for evolving. Watch for moles that change in size, shape, color or height. Moles may also evolve to develop new signs and symptoms, such as itchiness or bleeding. Cancerous (malignant) moles vary greatly in appearance. Some may show all of the changes listed above. Others may have only one or two unusual characteristics.",643,Moles "Primary exercise headaches: These headaches: Are usually described as throbbing Occur during or after strenuous exercise Affect both sides of the head in most cases Secondary exercise headaches These headaches may cause: The same symptoms as primary exercise headaches Vomiting Loss of consciousness Double vision Neck stiffness Primary exercise headaches typically last between five minutes and 48 hours, while secondary exercise headaches usually last at least a day and sometimes linger for several days or longer.",359,Exercise Headaches "among others: Feeling that you have to use the drug regularly — daily or even several times a day Having intense urges for the drug that block out any other thoughts Over time, needing more of the drug to get the same effect Taking larger amounts of the drug over a longer period of time than you intended Making certain that you maintain a supply of the drug Spending money on the drug, even though you can't afford it Not meeting obligations and work responsibilities, or cutting back on social or recreational activities because of drug use Continuing to use the drug, even though you know it's causing problems in your life or causing you physical or psychological harm Doing things to get the drug that you normally wouldn't do, such as stealing Driving or doing other risky activities when you're under the influence of the drug Spending a good deal of time getting the drug, using the drug or recovering from the effects of the drug Failing in your attempts to stop using the drug Experiencing withdrawal symptoms when you attempt to stop taking the drug Recognizing unhealthy drug use in family members Sometimes it's difficult to distinguish normal teenage moodiness or anxiety from signs of drug use. Possible signs that your teenager or other family member is using drugs include: Problems at school or work — frequently missing school or work, a sudden disinterest in school activities or work, or a drop in grades or work performance Physical health issues — lack of energy and motivation, weight loss or gain, or red eyes Neglected appearance — lack of interest in clothing, grooming or looks Changes in behavior — major efforts to bar family members from entering the teenager's room or being secretive about going out with friends; or drastic changes in behavior and in relationships with family and friends Money issues — sudden requests for money without a reasonable explanation; or your discovery that money is missing or has been stolen or that items have disappeared from your home, indicating maybe they're being sold to support drug use Recognizing signs of drug use or intoxication Signs and symptoms of drug use or intoxication may vary, depending on the type of drug. Below you'll find several examples. Marijuana, hashish and other cannabis-containing substances People use cannabis by smoking, eating or inhaling a vaporized form of the drug. Cannabis often precedes or is used along with other substances, such as alcohol or illegal drugs, and is often the first drug tried. Signs and symptoms of recent use can include: A sense of euphoria or feeling ""high"" A heightened sense of visual, auditory and taste perception Increased blood pressure and heart rate Red eyes Dry mouth Decreased coordination Difficulty concentrating or remembering Slowed reaction time Anxiety or paranoid thinking Cannabis odor on clothes or yellow fingertips Major cravings for certain foods at unusual times Long-term use is often associated with: Decreased mental sharpness Poor performance at school or at work Ongoing cough and frequent lung infections K2, Spice and bath salts Two groups of synthetic drugs — synthetic cannabinoids and substituted or synthetic cathinones — are illegal in most states. The effects of these drugs can be dangerous and unpredictable, as there is no quality control and some ingredients may not be known. Synthetic cannabinoids, also called K2 or Spice, are sprayed on dried herbs and then smoked, but can be prepared as an herbal tea. A liquid form can be vaporized in electronic cigarettes. Despite manufacturer claims, these are chemical compounds rather than ""natural"" or harmless products. These drugs can produce a ""high"" similar to marijuana and have become a popular but dangerous alternative. Signs and symptoms of recent use can include: A sense of euphoria or feeling ""high"" Elevated mood An altered sense of visual, auditory and taste perception Extreme anxiety or agitation Paranoia Hallucinations Increased heart rate and blood pressure or heart attack Vomiting Confusion Violent behavior Substituted cathinones, also called ""bath salts,"" are mind-altering (psychoactive) substances similar to amphetamines such as ecstasy (MDMA) and cocaine. Packages are often labeled as other products to avoid detection. Despite the name, these are not bath products such as Epsom salts. Substituted cathinones can be eaten, snorted, inhaled or injected and are highly addictive. These drugs can cause severe intoxication, which results in dangerous health effects or even death. Signs and symptoms of recent use can include: Feeling ""high"" Increased sociability Increased energy and agitation Increased sex drive Increased heart rate and blood pressure Problems thinking clearly Loss of muscle control Paranoia Panic attacks Hallucinations Delirium Psychotic and violent behavior Barbiturates, benzodiazepines and hypnotics Barbiturates, benzodiazepines and hypnotics are prescription central nervous system depressants. They're often used and misused in search for a sense of relaxation or a desire to ""switch off"" or forget stress-related thoughts or feelings. Barbiturates. An example is phenobarbital. Benzodiazepines. Examples include sedatives, such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), clonazepam (Klonopin) and chlordiazepoxide (Librium). Hypnotics. Examples include prescription sleeping medicines such as zolpidem (Ambien) and zaleplon (Sonata). Signs and symptoms of recent use can include: Drowsiness Slurred speech Lack of coordination Irritability or changes in mood Problems concentrating or thinking clearly Memory problems Involuntary eye movements Lack of inhibition Slowed breathing and reduced blood pressure Falls or accidents Dizziness Meth, cocaine and other stimulants Stimulants include amphetamines, meth (methamphetamine), cocaine, methylphenidate (Ritalin, Concerta, others) and amphetamine-dextroamphetamine (Adderall XR, Mydayis). They're often used and misused in search of a ""high,"" or to boost energy, to improve performance at work or school, or to lose weight or control appetite. Signs and symptoms of recent use can include: Feeling of happy excitement and too much confidence Increased alertness Increased energy and restlessness Behavior changes or aggression Rapid or rambling speech Larger than usual pupils, the black circles in the middle of the eyes Confusion, delusions and hallucinations Irritability, anxiety or paranoia Changes in heart rate, blood pressure and body temperature Nausea or vomiting with weight loss Poor judgment Nasal congestion and damage to the mucous membrane of the nose (if snorting drugs) Mouth sores, gum disease and tooth decay from smoking drugs (""meth mouth"") Insomnia Depression as the drug wears off Club drugs Club drugs are commonly used at clubs, concerts and parties. Examples include methylenedioxymethamphetamine, also called MDMA, ecstasy or molly, and gamma-hydroxybutyric acid, known as GHB. Other examples include ketamine and flunitrazepam or Rohypnol ― a brand used outside the U.S. ― also called roofie. These drugs are not all in the same category, but they share some similar effects and dangers, including long-term harmful effects. Because GHB and flunitrazepam can cause sedation, muscle relaxation, confusion and memory loss, the potential for sexual misconduct or sexual assault is associated with the use of these drugs. GHB Signs and symptoms of use of club drugs can include: Hallucinations Paranoia Larger than usual pupils Chills and sweating Involuntary shaking (tremors) Behavior changes Muscle cramping and teeth clenching Muscle relaxation, poor coordination or problems moving Reduced inhibitions Heightened or altered sense of sight, sound and taste Poor judgment Memory problems or loss of memory Reduced consciousness Increased or decreased heart rate and blood pressure Hallucinogens Use of hallucinogens can produce different signs and symptoms, depending on the drug. The most common hallucinogens are lysergic acid diethylamide (LSD) and phencyclidine (PCP). LSD use may cause: LSD Hallucinations Greatly reduced perception of reality, for example, interpreting input from one of your senses as another, such as hearing colors Impulsive behavior Rapid shifts in emotions Permanent mental changes in perception Rapid heart rate and high blood pressure Tremors Flashbacks, a reexperience of the hallucinations — even years later PCP use may cause: PCP A feeling of being separated from your body and surroundings Hallucinations Problems with coordination and movement Aggressive, possibly violent behavior Involuntary eye movements Lack of pain sensation Increase in blood pressure and heart rate Problems with thinking and memory Problems speaking Poor judgment Intolerance to loud noise Sometimes seizures or coma Inhalants Signs and symptoms of inhalant use vary, depending on the substance. Some commonly inhaled substances include glue, paint thinners, correction fluid, felt tip marker fluid, gasoline, cleaning fluids and household aerosol products. Due to the toxic nature of these substances, users may develop brain damage or sudden death. Signs and symptoms of use can include: Possessing an inhalant substance without a reasonable explanation Brief happy excitement Behaving as if drunk Reduced ability to keep impulses under control Aggressive behavior or eagerness to fight Dizziness Nausea or vomiting Involuntary eye movements Appearing under the influence of drugs, with slurred speech, slow movements and poor coordination Irregular heartbeats Tremors Lingering odor of inhalant material Rash around the nose and mouth Opioid painkillers Opioids are narcotic, painkilling drugs produced from opium or made synthetically. This class of drugs includes, among others, heroin, morphine, codeine, methadone, fentanyl and oxycodone. Sometimes called the ""opioid epidemic,"" addiction to opioid prescription pain medicines has reached an alarming rate across the United States. Some people who've been using opioids over a long period of time may need physician-prescribed temporary or long-term drug substitution during treatment. Signs and symptoms of narcotic use and dependence can include: A sense of feeling ""high"" Reduced sense of pain Agitation, drowsiness or sedation Slurred speech Problems with attention and memory Pupils that are smaller than usual Lack of awareness or inattention to surrounding people and things Problems with coordination Depression Confusion Constipation Runny nose or nose sores (if snorting drugs) Needle marks (if injecting drugs)",306,Drug Addiction "Signs and symptoms of ocular rosacea may include: Red, burning, itchy or watering eyes Dry eyes Grittiness or the feeling of having a foreign body in the eye or eyes Blurred vision Sensitivity to light (photophobia) Dilated small blood vessels on the white part of the eye that are visible when you look in a mirror Red, swollen eyelids Recurrent eye or eyelid infections, such as pink eye (conjunctivitis), blepharitis, sties or chalazia The severity of ocular rosacea symptoms doesn't always match the severity of skin symptoms.",693,Ocular Rosacea Signs and symptoms of desmoplastic small round cell tumors in the abdomen include: Swelling of the abdomen Abdominal pain Constipation Difficulty urinating,314,Dsrct "The range of signs and symptoms include: Weak bones that break easily (osteoporosis) Kidney stones Excessive urination Stomach (abdominal) pain Tiring easily or weakness Depression or forgetfulness Bone and joint pain Frequent complaints of illness with no clear cause Nausea, vomiting or loss of appetite",499,Hyperparathyroidism "In: Crohn's disease, any part of your small or large intestine can be involved. It may involve multiple segments, or it may be continuous. In some people, the disease is only in the colon, which is part of the large intestine. Signs and symptoms of Crohn's disease can range from mild to severe. They usually develop gradually, but sometimes will come on suddenly, without warning. You may also have periods of time when you have no signs or symptoms (remission). When the disease is active, symptoms typically include: Diarrhea Fever Fatigue Abdominal pain and cramping Blood in your stool Mouth sores Reduced appetite and weight loss Pain or drainage near or around the anus due to inflammation from a tunnel into the skin (fistula) Other signs and symptoms People with severe Crohn's disease may also experience symptoms outside of the intestinal tract, including: Inflammation of skin, eyes and joints Inflammation of the liver or bile ducts Kidney stones Iron deficiency (anemia) Delayed growth or sexual development, in children",255,Crohns Disease "Symptoms often include: Pain, often described as a dull ache, especially when moving the hurt limb or joint Tenderness Mild swelling",972,Tendinitis Thalassemia signs and symptoms can include: Fatigue Weakness Pale or yellowish skin Facial bone deformities Slow growth Abdominal swelling Dark urine Some babies show signs and symptoms of thalassemia at birth; others develop them during the first two years of life. Some people who have only one affected hemoglobin gene don't have thalassemia symptoms.,979,Thalassemia "you may experience some of the following: Pale skin Lightheadedness Tunnel vision — your field of vision narrows so that you see only what's in front of you Nausea Feeling warm A cold, clammy sweat Blurred vision During a vasovagal syncope episode, bystanders may notice: Jerky, abnormal movements A slow, weak pulse Dilated pupils Recovery after a vasovagal episode generally begins in less than a minute. However, if you stand up too soon after fainting — within about 15 to 30 minutes — you're at risk of fainting again.",1050,Vasovagal Syncope "They may include: Hives Itchy, irritated skin Nasal stuffiness (congestion) Swelling of the lips, face, tongue and throat, or other parts of the body Wheezing or trouble breathing Coughing and choking or a tight feeling in the throat Belly (abdominal) pain, diarrhea, nausea or vomiting Dizziness, lightheadedness or fainting Anaphylaxis Allergies can cause a severe, potentially life-threatening allergic reaction known as anaphylaxis. It can occur within seconds to minutes after exposure to something you're allergic to ⸺ and worsens quickly. An anaphylactic reaction to shellfish is a medical emergency. Anaphylaxis requires immediate treatment with an epinephrine (adrenaline) injection and a follow-up trip to the emergency room. If anaphylaxis isn't treated right away, it can be fatal. Anaphylaxis causes the immune system to release a flood of chemicals that can cause you to go into shock. Signs and symptoms of anaphylaxis include: A swollen throat or tongue or a tightness in the throat (airway constriction) that makes it difficult for you to breathe Coughing, choking or wheezing with trouble breathing Shock, with a severe drop in your blood pressure and a rapid or weak pulse Severe skin rash, hives, itching or swelling Nausea, vomiting or diarrhea Dizziness, lightheadedness or fainting",901,Shellfish Allergy "Signs and symptoms of scoliosis may include: Uneven shoulders One shoulder blade that appears more prominent than the other Uneven waist One hip higher than the other One side of the rib cage jutting forward A prominence on one side of the back when bending forward With most scoliosis cases, the spine will rotate or twist in addition to curving side to side. This causes the ribs or muscles on one side of the body to stick out farther than those on the other side.",887,Scoliosis "ALS: Difficulty walking or doing normal daily activities Tripping and falling Weakness in your legs, feet or ankles Hand weakness or clumsiness Slurred speech or trouble swallowing Muscle cramps and twitching in your arms, shoulders and tongue Inappropriate crying, laughing or yawning Cognitive and behavioral changes ALS often starts in the hands, feet or limbs, and then spreads to other parts of your body. As the disease advances and nerve cells are destroyed, your muscles get weaker. This eventually affects chewing, swallowing, speaking and breathing. ALS There's generally no pain in the early stages of ALS, and pain is uncommon in the later stages. ALS doesn't usually affect your bladder control or your senses.",44,Amyotrophic Lateral Sclerosis "A rotavirus infection usually starts within two days of exposure to the virus. Early symptoms are a fever and vomiting, followed by three to seven days of watery diarrhea. The infection can cause abdominal pain as well. In healthy adults, a rotavirus infection may cause only mild signs and symptoms or none at all.",866,Rotavirus The following can make sacroiliitis pain worse: Sleeping or sitting for a long time. Standing a long time. Having more weight on one leg than the other. Stair climbing. Running. Taking large steps when moving forward.,872,Sacroiliitis "Factitious disorder signs and symptoms may include: Clever and convincing medical or psychological problems Extensive knowledge of medical terms and diseases Vague or inconsistent symptoms Conditions that get worse for no apparent reason Conditions that don't respond as expected to standard therapies Seeking treatment from many different doctors or hospitals, which may include using a fake name Reluctance to allow doctors to talk to family or friends or to other health care professionals Frequent stays in the hospital Eagerness to have frequent testing or risky operations Many surgical scars or evidence of numerous procedures Having few visitors when hospitalized Arguing with doctors and staff Factious disorder imposed on another Factitious disorder imposed on another (previously called Munchausen syndrome by proxy) is when someone falsely claims that another person has physical or psychological signs or symptoms of illness, or causes injury or disease in another person with the intention of deceiving others. People with this disorder present another person as sick, injured or having problems functioning, claiming that medical attention is needed. Usually this involves a parent harming a child. This form of abuse can put a child in serious danger of injury or unnecessary medical care. How those with factitious disorder fake illness Because people with factitious disorder become experts at faking symptoms and diseases or inflicting real injuries upon themselves, it may be hard for health care professionals and loved ones to know if illnesses are real or not. People with factitious disorder make up symptoms or cause illnesses in several ways, such as: Exaggerating existing symptoms. Even when an actual medical or psychological condition exists, they may exaggerate symptoms to appear sicker or more impaired than is true. Making up histories. They may give loved ones, health care professionals or support groups a false medical history, such as claiming to have had cancer or AIDS. Or they may falsify medical records to indicate an illness. Faking symptoms. They may fake symptoms, such as stomach pain, seizures or passing out. Causing self-harm. They may make themselves sick, for example, by injecting themselves with bacteria, milk, gasoline or feces. They may injure, cut or burn themselves. They may take medications, such as blood thinners or drugs for diabetes, to mimic diseases. They may also interfere with wound healing, such as reopening or infecting cuts. Tampering. They may manipulate medical instruments to skew results, such as heating up thermometers. Or they may tamper with lab tests, such as contaminating their urine samples with blood or other substances.",364,Factitious Disorder "In most people, bundle branch block doesn't cause symptoms. Some people with the condition don't know they have bundle branch block. Rarely, symptoms of bundle branch block may include fainting (syncope) or feeling as if you're going to faint (presyncope).",158,Bundle Branch Block "People affected by color blindness may not be able to distinguish: Different shades of red and green Different shades of blue and yellow Any colors The most common color deficiency is an inability to see some shades of red and green. Often, a person who is red-green or blue-yellow deficient isn't completely insensitive to both colors. Defects can be mild, moderate or severe.",777,Poor Color Vision "Baby acne is small, inflamed bumps on a baby's face, neck, back or chest. It often develops within 2 to 4 weeks of birth. Many babies also develop tiny, pimple-like bumps on the face. These harmless spots, called milia, disappear on their own within a few weeks.",92,Baby Acne "They may include: Visual distortions, such as straight lines seeming bent. Reduced central vision in one or both eyes. The need for brighter light when reading or doing close-up work. Increased difficulty adapting to low light levels, such as when entering a dimly lit restaurant or theater. Increased blurriness of printed words. Difficulty recognizing faces. A well-defined blurry spot or blind spot in the field of vision. Dry macular degeneration can affect one or both eyes. If only one eye is affected, you may not notice any changes in your vision. This is because your good eye may compensate for the affected eye. And the condition doesn't affect the side vision, so it does not cause total blindness. Dry macular degeneration is one of two types of age-related macular degeneration. It can progress to wet macular degeneration, which is when blood vessels grow and leak under the retina. The dry type is more common, but it usually progresses slowly over years. The wet type is more likely to cause a relatively sudden change in vision resulting in serious vision loss.",310,Dry Macular Degeneration "among others: Headache Bulging or swelling of the eyes Bleeding in the nose, throat or ears If the cancer is in the urinary or reproductive system, signs and symptoms may include, among others: Trouble urinating and blood in the urine Difficulty with bowel movements A mass or bleeding in the vagina or rectum If the cancer is in the arms or legs, signs and symptoms may include, among others: Swelling or a lump in the arm or leg Pain in the affected area, though sometimes there is no pain",857,Rhabdomyosarcoma "Signs and symptoms of body dysmorphic disorder include: Being extremely preoccupied with a perceived flaw in appearance that to others can't be seen or appears minor Strong belief that you have a defect in your appearance that makes you ugly or deformed Belief that others take special notice of your appearance in a negative way or mock you Engaging in behaviors aimed at fixing or hiding the perceived flaw that are difficult to resist or control, such as frequently checking the mirror, grooming or skin picking Attempting to hide perceived flaws with styling, makeup or clothes Constantly comparing your appearance with others Frequently seeking reassurance about your appearance from others Having perfectionist tendencies Seeking cosmetic procedures with little satisfaction Avoiding social situations Preoccupation with your appearance and excessive thoughts and repetitive behaviors can be unwanted, difficult to control and so time-consuming that they can cause major distress or problems in your social life, work, school or other areas of functioning. You may excessively focus over one or more parts of your body. The bodily feature that you focus on may change over time. The most common features people tend to fixate about include: Face, such as nose, complexion, wrinkles, acne and other blemishes Hair, such as appearance, thinning and baldness Skin and vein appearance Breast size Muscle size and tone Genitalia A preoccupation with your body build being too small or not muscular enough (muscle dysmorphia) occurs almost exclusively in males. Insight about body dysmorphic disorder varies. You may recognize that your beliefs about your perceived flaws may be excessive or not be true, or think that they probably are true, or be absolutely convinced that they're true. The more convinced you are of your beliefs, the more distress and disruption you may experience in your life.",120,Body Dysmorphic Disorder "such as: Cushing's disease, multiple sclerosis or stroke. Bipolar II disorder is not a milder form of bipolar I disorder, but a separate diagnosis. While the manic episodes of bipolar I disorder can be severe and dangerous, individuals with bipolar II disorder can be depressed for longer periods, which can cause significant impairment. Although bipolar disorder can occur at any age, typically it's diagnosed in the teenage years or early 20s. Symptoms can vary from person to person, and symptoms may vary over time. Mania and hypomania Mania and hypomania are two distinct types of episodes, but they have the same symptoms. Mania is more severe than hypomania and causes more noticeable problems at work, school and social activities, as well as relationship difficulties. Mania may also trigger a break from reality (psychosis) and require hospitalization. Both a manic and a hypomanic episode include three or more of these symptoms: Abnormally upbeat, jumpy or wired Increased activity, energy or agitation Exaggerated sense of well-being and self-confidence (euphoria) Decreased need for sleep Unusual talkativeness Racing thoughts Distractibility Poor decision-making — for example, going on buying sprees, taking sexual risks or making foolish investments Major depressive episode A major depressive episode includes symptoms that are severe enough to cause noticeable difficulty in day-to-day activities, such as work, school, social activities or relationships. An episode includes five or more of these symptoms: Depressed mood, such as feeling sad, empty, hopeless or tearful (in children and teens, depressed mood can appear as irritability) Marked loss of interest or feeling no pleasure in all — or almost all — activities Significant weight loss when not dieting, weight gain, or decrease or increase in appetite (in children, failure to gain weight as expected can be a sign of depression) Either insomnia or sleeping too much Either restlessness or slowed behavior Fatigue or loss of energy Feelings of worthlessness or excessive or inappropriate guilt Decreased ability to think or concentrate, or indecisiveness Thinking about, planning or attempting suicide Other features of bipolar disorder Signs and symptoms of bipolar I and bipolar II disorders may include other features, such as anxious distress, melancholy, psychosis or others. The timing of symptoms may include diagnostic labels such as mixed or rapid cycling. In addition, bipolar symptoms may occur during pregnancy or change with the seasons. Symptoms in children and teens Symptoms of bipolar disorder can be difficult to identify in children and teens. It's often hard to tell whether these are normal ups and downs, the results of stress or trauma, or signs of a mental health problem other than bipolar disorder. Children and teens may have distinct major depressive or manic or hypomanic episodes, but the pattern can vary from that of adults with bipolar disorder. And moods can rapidly shift during episodes. Some children may have periods without mood symptoms between episodes. The most prominent signs of bipolar disorder in children and teenagers may include severe mood swings that are different from their usual mood swings.",111,Bipolar Disorder "symptoms may include: Extreme exhaustion after physical or mental exercise. Problems with memory or thinking skills. Dizziness that worsens with moving from lying down or sitting to standing. Muscle or joint pain. Unrefreshing sleep. Some people with chronic fatigue syndrome have headaches, sore throats, and tender lymph nodes in the neck or armpits. People with the condition also may become extra sensitive to light, sound, smells, food and medicines.",211,Chronic Fatigue Syndrome "Other signs and symptoms may include: Cold feet after exercise Tingling or burning in your calf (paresthesia) Numbness in the calf area If the nearby vein (popliteal vein) also becomes trapped by the calf muscle, you may have: Heavy feeling in the leg Lower leg cramping at night Swelling in the calf area Changes in skin color around the calf muscle Blood clots in the lower leg (deep vein thrombosis) Symptoms typically affect young, otherwise healthy people under age 40.",779,Popliteal Artery Entrapment "Signs and symptoms of familial: Mediterranean fever usually begin during childhood. They occur in bouts called attacks that last 1-3 days. Arthritic attacks may last for weeks or months. Signs and symptoms of FMF attacks vary, but can include: FMF Fever Abdominal pain Chest pain, which can make it hard to breathe deeply Painful, swollen joints, usually in the knees, ankles and hips A red rash on your legs, especially below your knees Muscle aches A swollen, tender scrotum The attacks generally resolve spontaneously after a few days. Between attacks, you'll likely feel back to your typical health. Symptom-free periods may be as short as a few days or as long as several years. In some people, the first sign of FMF is amyloidosis. With amyloidosis, the protein amyloid A, which is not typically found in the body, builds up in organs ⸺ especially the kidneys ⸺ causing inflammation and interfering with their function.",368,Familial Mediterranean Fever "Vaginal agenesis may have these features: The genitals look like a typical female. The vagina may be shortened without a cervix at the end, or absent and marked only by a slight indentation where a vaginal opening would typically be located. There may be no uterus or one that's only partially developed. If there's tissue lining the uterus (endometrium), monthly cramping or chronic abdominal pain may occur. The ovaries typically are fully developed and functional, but they may be in an unusual location in the abdomen. Sometimes the pair of tubes that eggs travel through to get from the ovaries to the uterus (fallopian tubes) are absent or do not develop typically. Vaginal agenesis may also be associated with other issues, such as: Problems with development of the kidneys and urinary tract Developmental changes in the bones of the spine, ribs and wrists Hearing problems Other congenital conditions that also involve the heart, gastrointestinal tract and limb growth",1041,Vaginal Agenesis "coli: Diarrhea, which may range from mild and watery to severe and bloody Stomach cramping, pain or tenderness Nausea and vomiting, in some people",325,E Coli "They include: Excessive daytime sleepiness. People with narcolepsy fall asleep without warning. It can happen anywhere and at any time. It may happen when you're bored or during a task. For example, you may be working or talking with friends and suddenly fall asleep. It can be especially dangerous if you fall asleep while driving. You might fall asleep for only a few minutes or up to a half-hour. After waking, you'll often feel refreshed but you'll get sleepy again. You also may experience a decrease in how alert and focused you feel during the day. Daytime sleepiness often is the first symptom to appear. Feeling sleepy makes it hard to focus and function. Some people with narcolepsy continue doing a task when they fall asleep briefly. For example, you may fall asleep while writing, typing or driving. You might continue to perform that task while asleep. When you awaken, you can't remember what you did, and you probably didn't do it well. Sudden loss of muscle tone. This condition is called cataplexy. It can cause slurred speech or complete weakness of most muscles. Symptoms may last up to a few minutes. Cataplexy can't be controlled. It's triggered by intense emotions. Often the emotions that cause cataplexy are positive. Laughter or excitement may cause the symptoms. But sometimes fear, surprise or anger can cause the loss of muscle tone. For example, when you laugh, your head may drop without your control. Or your knees may suddenly lose strength, causing you to fall. Some people with narcolepsy experience only one or two episodes of cataplexy a year. Others have several episodes a day. Not everyone with narcolepsy has these symptoms. Sleep paralysis. People with narcolepsy often experience sleep paralysis. During sleep paralysis, you can't move or speak while falling asleep or upon waking. It's usually brief — lasting a few seconds or minutes. But it can be scary. You may be aware of it happening and can recall it afterward. Not everyone with sleep paralysis has narcolepsy. Hallucinations. Sometimes people see things that aren't there during sleep paralysis. Hallucinations also may happen in bed without sleep paralysis. These are called hypnagogic hallucinations if they happen as you fall asleep. They're called hypnopompic hallucinations if they happen upon waking. For example, you might feel as if there is a stranger in your bedroom. These hallucinations may be vivid and frightening because you may not be fully asleep when you begin dreaming. Changes in rapid eye movement (REM) sleep. REM sleep is when most dreaming happens. Typically, people enter REM sleep 60 to 90 minutes after falling asleep. But people with narcolepsy often move more quickly to REM sleep. They tend to enter REM sleep within 15 minutes of falling asleep. REM sleep also can happen at any time of the day. Other characteristics People with narcolepsy may have other sleep disorders. They might have obstructive sleep apnea, in which breathing starts and stops during the night. Or they may act out their dreams, known as REM sleep behavior disorder. Or they may have trouble falling asleep or staying asleep, called insomnia.",668,Narcolepsy "Cutaneous anthrax: Cutaneous anthrax Cutaneous anthrax Cutaneous anthrax You can contract anthrax when spores penetrate your skin, usually through an open wound. The infection begins as a raised, sometimes itchy, bump resembling an insect bite. But within a day or two, the bump develops into an open, usually painless sore with a black center. Cutaneous anthrax Cutaneous anthrax You can contract anthrax when spores penetrate your skin, usually through an open wound. Cutaneous anthrax You can contract anthrax when spores penetrate your skin, usually through an open wound. You can contract anthrax when spores penetrate your skin, usually through an open wound. A skin-related (cutaneous) anthrax infection enters your body through your skin, usually through a cut or other sore. It's by far the most common route of the disease. It's also the mildest. With appropriate treatment, cutaneous anthrax is seldom fatal. Signs and symptoms include: A raised, itchy bump resembling an insect bite that quickly develops into a painless sore with a black center Swelling in the sore and nearby lymph glands Sometimes, flu-like symptoms including fever and headache Gastrointestinal anthrax A gastrointestinal anthrax infection results from eating undercooked meat from an infected animal. It can affect your gastrointestinal tract from your throat to your colon. Signs and symptoms include: Nausea Vomiting Abdominal pain Headache Loss of appetite Fever Severe, bloody diarrhea in the later stages of the disease Sore throat and difficulty swallowing Swollen neck Inhalation anthrax Inhalation anthrax Inhalation anthrax Inhalation anthrax This illustration shows how the spores that cause inhalation anthrax — the most deadly form of anthrax infection — enter and affect the body. Inhalation anthrax Inhalation anthrax Inhalation anthrax Inhalation anthrax This illustration shows how the spores that cause inhalation anthrax — the most deadly form of anthrax infection — enter and affect the body. Inhalation anthrax Inhalation anthrax This illustration shows how the spores that cause inhalation anthrax — the most deadly form of anthrax infection — enter and affect the body. Inhalation anthrax This illustration shows how the spores that cause inhalation anthrax — the most deadly form of anthrax infection — enter and affect the body. This illustration shows how the spores that cause inhalation anthrax — the most deadly form of anthrax infection — enter and affect the body. Inhalation anthrax develops when you breathe in anthrax spores. It's the most deadly form of the disease, and is often fatal, even with treatment. Initial signs and symptoms include: Flu-like symptoms for a few hours or days, such as sore throat, mild fever, fatigue and muscle aches Mild chest discomfort Shortness of breath Nausea Coughing up blood Painful swallowing High fever Trouble breathing Shock — an acute medical condition involving collapse of the circulatory system Meningitis Injection anthrax This recently identified route of anthrax infection has so far been reported only in Europe. It's contracted through injecting illegal drugs. Initial signs and symptoms include: Redness at the area of injection (without an area that changes to black) Significant swelling Shock Multiple organ failure Meningitis",57,Anthrax such as: Milky nipple discharge Hair loss Headache Vision changes Excess facial hair Pelvic pain Acne,40,Amenorrhea "concussive symptoms include: Headaches. Dizziness. Fatigue. Irritability. Anxiety. Trouble falling asleep or sleeping too much. Loss of concentration and memory. Ringing in the ears. Blurry vision. Noise and light sensitivity. Rarely, decreases in taste and smell. Headaches after a concussion most often feel like tension-type headaches. These may be related to a neck injury that happened at the same time as the head injury. Or the headaches may feel like migraines.",781,Post Concussion Syndrome "pulmonary edema symptoms: Difficulty breathing (dyspnea) or extreme shortness of breath that worsens with activity or when lying down A feeling of suffocating or drowning that worsens when lying down A cough that produces frothy sputum that may have blood in it A rapid, irregular heartbeat (palpitations) Anxiety, restlessness or a feeling that something bad is about to happen Cold, clammy skin Wheezing or gasping for breath Long-term (chronic) pulmonary edema signs and symptoms Awakening at night with a cough or breathless feeling that may be relieved by sitting up Difficulty breathing with activity or when lying flat Fatigue More shortness of breath than usual when you're physically active New or worsening cough Rapid weight gain Swelling in the legs and feet Wheezing High-altitude pulmonary edema (HAPE) signs and symptoms HAPE can occur in adults and children who travel to or exercise at high altitudes. Symptoms are similar to those that occur with acute pulmonary edema and can include: HAPE Headache, which may be the first symptom Shortness of breath with activity, which becomes shortness of breath at rest Not being able to exercise as much as you once could Dry cough, at first Later, a cough that produces frothy sputum that may look pink or have blood in it A very fast heartbeat (tachycardia) Weakness Chest pain Low fever Symptoms of high-altitude pulmonary edema (HAPE) tend to get worse at night.",826,Pulmonary Edema "early signs and symptoms can include: Fever Fatigue, weakness or general feeling of being unwell Dizziness Muscle, bone or joint aches Nausea and vomiting Diarrhea Symptoms that can become life-threatening More-severe symptoms include: Bleeding under the skin, in internal organs, or from the mouth, eyes or ears Nervous system malfunctions Coma Delirium Kidney failure Respiratory failure Liver failure",1058,Viral Hemorrhagic Fevers "they may include: Difficulty breathing Rapid, shallow breathing Wheezing Cough",80,Atelectasis "including: Fever Cough Tiredness Shortness of breath Headache Chills Night sweats Joint aches and muscle soreness Red, spotty rash, mainly on lower legs but sometimes on the chest, arms and back If you don't become ill or have symptoms from valley fever, you may only find out you've been infected later. You may find out when you have a positive skin or blood test or when small areas of residual infection in the lungs (nodules) show up on a routine chest X-ray. The nodules typically don't cause problems, but they can look like cancer on X-rays. If you develop symptoms, especially severe ones, the course of the disease is highly variable. It can take months to fully recover. Fatigue and joint aches can last even longer. The disease's severity depends on several factors, including your overall health and the number of fungus spores you inhale. Chronic coccidioidomycosis If the initial coccidioidomycosis infection doesn't completely resolve, it may progress to a chronic form of pneumonia. This complication is most common in people with weakened immune systems. Signs and symptoms include: Low-grade fever Weight loss Cough Chest pain Blood-tinged sputum (matter discharged during coughing) Nodules in the lungs Disseminated coccidioidomycosis The most serious form of the disease, disseminated coccidioidomycosis, is uncommon. It occurs when the infection spreads (disseminates) beyond the lungs to other parts of the body. Most often these parts include the skin, bones, liver, brain, heart, and the membranes that protect the brain and spinal cord (meninges). Signs and symptoms of disseminated disease depend on the body parts affected and may include: Nodules, ulcers and skin lesions that are more serious than the rash that sometimes occurs with initial infection Painful lesions in the skull, spine or other bones Painful, swollen joints, especially in the knees or ankles Meningitis — an infection of the membranes and fluid surrounding the brain and spinal cord",1045,Valley Fever "Swollen lymph nodes: Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. The inset shows three swollen lymph nodes below the lower jaw. Swollen lymph nodes Swollen lymph nodes Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. One of the most common places to find swollen lymph nodes is in the neck. Signs and symptoms of lymphoma may include: Painless swelling of lymph nodes in your neck, armpits or groin Persistent fatigue Fever Night sweats Shortness of breath Unexplained weight loss Itchy skin",594,Lymphoma "Nerves are classified into: Sensory nerves that receive sensation, such as temperature, pain, vibration or touch, from the skin Motor nerves that control muscle movement Autonomic nerves that control functions such as blood pressure, perspiration, heart rate, digestion and bladder function Signs and symptoms of peripheral neuropathy might include: Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms Sharp, jabbing, throbbing or burning pain Extreme sensitivity to touch Pain during activities that shouldn't cause pain, such as pain in your feet when putting weight on them or when they're under a blanket Lack of coordination and falling Muscle weakness Feeling as if you're wearing gloves or socks when you're not Paralysis if motor nerves are affected If autonomic nerves are affected, signs and symptoms might include: Heat intolerance Excessive sweating or not being able to sweat Bowel, bladder or digestive problems Drops in blood pressure, causing dizziness or lightheadedness Peripheral neuropathy can affect one nerve (mononeuropathy), two or more nerves in different areas (multiple mononeuropathy), or many nerves (polyneuropathy). Carpal tunnel syndrome is an example of mononeuropathy. Most people with peripheral neuropathy have polyneuropathy.",745,Peripheral Neuropathy "of the affected pupil in dim light: Drooping of the upper eyelid (ptosis) Slight elevation of the lower lid, sometimes called upside-down ptosis Sunken appearance of the affected eye Little or no sweating (anhidrosis) on the affected side of the face Signs and symptoms, particularly ptosis and anhidrosis, may be subtle and difficult to detect. Children Additional signs and symptoms in children with Horner syndrome may include: Lighter iris color in the affected eye of a child under the age of 1 Change in color on the affected side of the face that would typically appear from heat, physical exertion or emotional reactions",487,Horner Syndrome "The main symptom of infertility is the inability to get pregnant. A menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular or absent can mean that you're not ovulating. There might be no other signs or symptoms.",372,Female Infertility "Warning signs of bedsores or pressure ulcers are: Unusual changes in skin color or texture Swelling Pus-like draining An area of skin that feels cooler or warmer to the touch than other areas Tender areas Bedsores fall into one of several stages based on their depth, severity and other characteristics. The degree of skin and tissue damage ranges from changes in skin color to a deep injury involving muscle and bone. Common sites of pressure ulcers For people who use wheelchairs, bedsores often occur on skin over the following sites: Tailbone or buttocks Shoulder blades and spine Backs of arms and legs where they rest against the chair For people who need to stay in bed, bedsores may happen on: The back or sides of the head The shoulder blades The hip, lower back or tailbone The heels, ankles and skin behind the knees",102,Bed Sores "signs and symptoms may include: Cough Production of mucus (sputum), which can be clear, white, yellowish-gray or green in color — rarely, it may be streaked with blood Fatigue Shortness of breath Slight fever and chills Chest discomfort If you have acute bronchitis, you might have cold symptoms, such as a mild headache or body aches. While these symptoms usually improve in about a week, you may have a nagging cough that lingers for several weeks. Chronic bronchitis is defined as a productive cough that lasts at least three months, with recurring bouts occurring for at least two consecutive years. If you have chronic bronchitis, you're likely to have periods when your cough or other symptoms worsen. At those times, you may have an acute infection on top of chronic bronchitis. When to see a doctor See your doctor if your cough: Lasts more than three weeks Prevents you from sleeping Is accompanied by fever higher than 100.4 F (38 C) Produces discolored mucus Produces blood Is associated with wheezing or shortness of breath",151,Bronchitis "They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren't there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.",90,Autonomic Neuropathy "Symptoms include: Coughing. Wheezing. Shortness of breath. Chest tightness or pain. Fatigue during exercise. Poorer than expected athletic performance. Avoiding activity, which happens mostly in young children.",360,Exercise Induced Asthma "MCI: You forget things more often. You miss appointments or social events. You lose your train of thought. Or you can't follow the plot of a book or movie. You have trouble following a conversation. You find it hard to make decisions, finish a task or follow instructions. You start to have trouble finding your way around places you know well. You begin to have poor judgment. Your family and friends notice any of these changes. If you have MCI, you also may experience: MCI Depression Anxiety A short temper and aggression A lack of interest",633,Mild Cognitive Impairment "The signs and symptoms of bullous pemphigoid may include: Itching skin, weeks or months before blisters form Large blisters that don't easily rupture when touched, often along creases or folds in the skin Skin around the blisters that is normal, reddish or darker than normal Eczema or a hive-like rash Small blisters or sores in the mouth or other mucous membranes (benign mucous membrane pemphigoid)",157,Bullous Pemphigoid "Atopic dermatitis on the chest: Atopic dermatitis on the chest Atopic dermatitis on the chest Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots. Atopic dermatitis on the chest Atopic dermatitis on the chest Atopic dermatitis on the chest Atopic dermatitis on the chest Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots. Atopic dermatitis on the chest Atopic dermatitis on the chest Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots. Atopic dermatitis on the chest Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots. Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots. Infantile eczema Infantile eczema Infantile eczema Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin. Infantile eczema Infantile eczema Infantile eczema Infantile eczema Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin. Infantile eczema Infantile eczema Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin. Infantile eczema Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin. Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin. Atopic dermatitis (eczema) symptoms can appear anywhere on the body and vary widely from person to person. They may include: Dry, cracked skin Itchiness (pruritus) Rash on swollen skin that varies in color depending on your skin color Small, raised bumps, on brown or Black skin Oozing and crusting Thickened skin Darkening of the skin around the eyes Raw, sensitive skin from scratching Atopic dermatitis often begins before age 5 and may continue into the teen and adult years. For some people, it flares and then clears up for a time, even for several years.",82,Atopic Dermatitis Eczema "s elbow: Golfer's elbow Golfer's elbow The pain of golfer's elbow occurs primarily where the tendons of the forearm muscles attach to the bony bump on the inside of the elbow (medial epicondyle). By contrast, the pain of tennis elbow usually occurs at the bony bump on the outside of the elbow (lateral epicondyle). Golfer's elbow Golfer's elbow Golfer's elbow Golfer's elbow The pain of golfer's elbow occurs primarily where the tendons of the forearm muscles attach to the bony bump on the inside of the elbow (medial epicondyle). Golfer's elbow Golfer's elbow The pain of golfer's elbow occurs primarily where the tendons of the forearm muscles attach to the bony bump on the inside of the elbow (medial epicondyle). Golfer's elbow The pain of golfer's elbow occurs primarily where the tendons of the forearm muscles attach to the bony bump on the inside of the elbow (medial epicondyle). The pain of golfer's elbow occurs primarily where the tendons of the forearm muscles attach to the bony bump on the inside of the elbow (medial epicondyle). Golfer's elbow is characterized by: Pain and tenderness. Usually felt on the inner side of your elbow, the pain sometimes extends along the inner side of your forearm. Pain typically worsens with certain movements. Stiffness. Your elbow may feel stiff, and making a fist might hurt. Weakness. You may have weakness in your hands and wrists. Numbness or tingling. These sensations might radiate into one or more fingers — usually the ring and little fingers. The pain of golfer's elbow can come on suddenly or gradually. The pain might worsen with certain movements, such as swinging a golf club.",422,Golfers Elbow "A lump that can be felt through the skin that may or may not be painful: Bone pain A broken bone that happens unexpectedly, such as with a minor injury or no injury at all Abdominal pain Weight loss Causes It's not clear what causes most sarcomas. In general, cancer forms when changes (mutations) happen in the DNA within cells. The DNA inside a cell is packaged into a large number of individual genes, each of which contains a set of instructions telling the cell what functions to perform, as well as how to grow and divide. Mutations might tell cells to grow and divide uncontrollably and to continue living when normal cells would die. If this happens, the accumulating abnormal cells can form a tumor. Cells can break away and spread (metastasize) to other parts of the body. Risk factors Factors that can increase the risk of sarcoma include: Inherited syndromes. Some syndromes that increase the risk of cancer can be passed from parents to children. Examples of syndromes that increase the risk of sarcoma include familial retinoblastoma and neurofibromatosis type 1. Radiation therapy for cancer. Radiation treatment for cancer increases the risk of developing a sarcoma later. Chronic swelling (lymphedema). Lymphedema is swelling caused by a backup of lymph fluid that occurs when the lymphatic system is blocked or damaged. It increases the risk of a type of sarcoma called angiosarcoma. Exposure to chemicals. Certain chemicals, such as some industrial chemicals and herbicides, can increase the risk of sarcoma that affects the liver. Exposure to viruses. The virus called human herpesvirus 8 can increase the risk of a type of sarcoma called Kaposi's sarcoma in people with weakened immune systems. By Mayo Clinic Staff By Mayo Clinic Staff Sarcoma care at Mayo Clinic",876,Sarcoma you may experience some of these signs or symptoms: Red or swollen gums Tender or bleeding gums Jaw pain Swelling around the jaw Bad breath An unpleasant taste in your mouth Difficulty opening your mouth,1073,Wisdom Teeth "Symptoms include: Vomiting after feeding. The baby may vomit forcefully, ejecting breast milk or formula up to several feet away. This is known as projectile vomiting. Vomiting might be mild at first. But over time, it becomes more severe as the pylorus opening narrows. The vomit may sometimes contain blood. Persistent hunger. Babies who have pyloric stenosis often want to eat soon after vomiting. Stomach contractions. You may notice wavelike contractions that ripple across your baby's upper stomach area soon after feeding but before vomiting. These contractions are part of the digestive process known as peristalsis. The contractions are caused by stomach muscles trying to force food through the narrowed pylorus. Dehydration. Your baby might cry without tears or become lethargic. You might find yourself changing fewer wet diapers or diapers that aren't as wet as you expect. Changes in bowel movements. Since pyloric stenosis prevents food from reaching the intestines, babies with this condition might be constipated. Weight problems. Pyloric stenosis can keep a baby from gaining weight, and sometimes can cause weight loss.",831,Pyloric Stenosis "Testicular lumps: Testicular lumps Testicular lumps Pain, swelling or lumps in your testicle or groin area may be a sign or symptom of testicular cancer or other medical conditions requiring treatment. Testicular lumps Testicular lumps Testicular lumps Testicular lumps Pain, swelling or lumps in your testicle or groin area may be a sign or symptom of testicular cancer or other medical conditions requiring treatment. Testicular lumps Testicular lumps Pain, swelling or lumps in your testicle or groin area may be a sign or symptom of testicular cancer or other medical conditions requiring treatment. Testicular lumps Pain, swelling or lumps in your testicle or groin area may be a sign or symptom of testicular cancer or other medical conditions requiring treatment. Pain, swelling or lumps in your testicle or groin area may be a sign or symptom of testicular cancer or other medical conditions requiring treatment. Signs and symptoms of testicular cancer include: A lump or swelling in either testicle A feeling of heaviness in the scrotum A dull ache in the lower belly or groin Sudden swelling in the scrotum Pain or discomfort in a testicle or the scrotum Enlargement or tenderness of the breast tissue Back pain Usually testicular cancer only happens in one testicle.",975,Testicular Cancer Care "The following can increase the pain: Walking up or down stairs. Kneeling or squatting. Sitting with a bent knee for long periods of time. When to see your doctor If the knee pain doesn't improve within a few days or it gets harder to move the knee, call your health care provider.",723,Patellofemoral Pain Syndrome "Symptoms of an anal fistula can include: An opening on the skin around the anus A red, inflamed area around the tunnel opening Oozing of pus, blood or stool from the tunnel opening Pain in the rectum and anus, especially when sitting or passing stool Fever",47,Anal Fistula "These are common features of ganglion cysts: Location. Ganglion cysts most often develop along the tendons or joints of wrists or hands. The next most common locations are the ankles and feet. These cysts grow near other joints too. Shape and size. Ganglion cysts are round or oval. Some are too small to feel. The size of a cyst can change, often getting larger over time with joint movement. Pain. Ganglion cysts usually are painless. But if a cyst presses on a nerve or other structures, it can cause pain, tingling, numbness or muscle weakness.",398,Ganglion Cyst "Staph infection: Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph infection Staph infection Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph infection Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. Staph infection MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. MRSA infections start out as small red bumps that can quickly turn into deep, painful abscesses. MRSA Staph infections can range from minor skin problems to life-threatening illness. For example, endocarditis, a serious infection of the inner lining of your heart (endocardium) can be caused by staph bacteria. Signs and symptoms of staph infections vary widely, depending on the location and severity of the infection. Skin infections Skin infections caused by staph bacteria include: Boils. The most common type of staph infection is the boil. This is a pocket of pus that develops in a hair follicle or oil gland. The skin over the infected area usually becomes red and swollen. If a boil breaks open, it will probably drain pus. Boils occur most often under the arms or around the groin or buttocks. Impetigo. This contagious, often painful rash can be caused by staph bacteria. Impetigo usually has large blisters that may ooze fluid and develop a honey-colored crust. Cellulitis. Cellulitis is an infection of the deeper layers of skin. It causes redness and swelling on the surface of your skin. Sores or areas of oozing discharge may develop, too. Staphylococcal scalded skin syndrome. Toxins produced by the staph bacteria may cause staphylococcal scalded skin syndrome. Affecting mostly babies and children, this condition includes a fever, a rash and sometimes blisters. When the blisters break, the top layer of skin comes off. This leaves a red, raw surface that looks like a burn. Food poisoning Staph bacteria are one of the most common causes of food poisoning. The bacteria multiply in food and produce toxins that make you sick. Symptoms come on quickly, usually within hours of eating a contaminated food. Symptoms usually disappear quickly, too, often lasting just half a day. A staph infection in food usually doesn't cause a fever. Signs and symptoms you can expect with this type of staph infection include: Nausea and vomiting Diarrhea Dehydration Low blood pressure Bacteremia Also known as a bloodstream infection, bacteremia occurs when staph bacteria enter the bloodstream. A fever and low blood pressure are signs of bacteremia. The bacteria can travel to locations deep within your body to cause infections that affect: Internal organs, such as your brain (meningitis), heart (endocarditis) or lungs (pneumonia) Bones and muscles Surgically implanted devices, such as artificial joints or cardiac pacemakers Toxic shock syndrome This life-threatening condition results from toxins produced by some strains of staph bacteria. The condition has been linked to certain types of tampons, skin wounds and surgery. It usually develops suddenly with: A high fever Nausea and vomiting A rash on your palms and soles that looks like a sunburn Confusion Muscle aches Diarrhea Stomach pain Septic arthritis Septic arthritis is often caused by a staph infection. The bacteria often target the knees, shoulders, hips, and fingers or toes. Artificial joints may also be at risk of infection. Signs and symptoms may include: Joint swelling Severe pain in the affected joint Fever",939,Staph Infections "Typical agoraphobia symptoms include fear of: Leaving home alone. Crowds or waiting in line. Enclosed spaces, such as movie theaters, elevators or small stores. Open spaces, such as parking lots, bridges or malls. Using public transportation, such as a bus, plane or train. These situations cause anxiety because you fear you won't be able to escape or find help if you start to feel panicked. Or you may fear having other disabling or embarrassing symptoms, such as dizziness, fainting, falling or diarrhea. In addition: Your fear or anxiety is out of proportion to the actual danger of the situation. You avoid the situation, you need a companion to go with you, or you endure the situation but are extremely upset. You have major distress or problems with social situations, work or other areas in your life because of the fear, anxiety or avoidance. Your fear and avoidance usually lasts six months or longer. Panic disorder and agoraphobia Some people have panic disorder in addition to agoraphobia. Panic disorder is a type of anxiety disorder that includes panic attacks. A panic attack is a sudden feeling of extreme fear that reaches a peak within a few minutes and triggers a variety of intense physical symptoms. You might think that you're totally losing control, having a heart attack or even dying. Fear of another panic attack can lead to avoiding similar situations or the place where it happened in an attempt to prevent future panic attacks. Symptoms of a panic attack can include: Rapid heart rate. Trouble breathing or a feeling of choking. Chest pain or pressure. Lightheadedness or dizziness. Feeling shaky, numb or tingling. Sweating too much. Sudden flushing or chills. Upset stomach or diarrhea. Feeling a loss of control. Fear of dying.",26,Agoraphobia "Bulging fontanel: Bulging fontanel Bulging fontanel One of the major signs of encephalitis in infants is bulging of the soft spots (fontanels) of the baby's skull. Pictured here is the anterior fontanel. Other fontanels are found on the sides and back of an infant's head. Bulging fontanel Bulging fontanel Bulging fontanel Bulging fontanel One of the major signs of encephalitis in infants is bulging of the soft spots (fontanels) of the baby's skull. Bulging fontanel Bulging fontanel One of the major signs of encephalitis in infants is bulging of the soft spots (fontanels) of the baby's skull. Bulging fontanel One of the major signs of encephalitis in infants is bulging of the soft spots (fontanels) of the baby's skull. One of the major signs of encephalitis in infants is bulging of the soft spots (fontanels) of the baby's skull. Encephalitis may cause many different symptoms including confusion, personality changes, seizures or problems with movement. Encephalitis also may cause changes in sight or hearing. Most people with infectious encephalitis have flu-like symptoms, such as: Headache. Fever. Aches in muscles or joints. Fatigue or weakness. Typically, these are followed by more-severe symptoms over a period of hours to days, such as: Stiff neck. Confusion, agitation or hallucinations. Seizures. Loss of sensation or being unable to move certain areas of the face or body. Irregular movements. Muscle weakness. Problems with speech or hearing. Loss of consciousness, including coma. In infants and young children, signs and symptoms also might include: Bulging in the soft spots of an infant's skull, known as fontanels. Nausea and vomiting. Stiffness affecting the whole body. Poor feeding or not waking for a feeding. Irritability. In cases of autoimmune encephalitis, symptoms may develop more slowly over several weeks. Flu-like symptoms are less common, but can sometimes happen weeks before more-severe symptoms start. Symptoms are different for everyone, but it's common for people to have a combination of symptoms including: Changes in personality. Memory loss. Problems understanding what is real and what is not, known as psychosis. Seeing or hearing things that aren't there. These are called hallucinations. Changes in vision. Sleep problems. Loss of sensation. Problems walking. Abnormal movements. Bladder and bowel problems.",337,Encephalitis "Eye with uvea: Eye with uvea Eye with uvea The uvea consists of structures of the eye beneath the white of the eye (sclera). It has three parts: (1) the iris, which is the colored part of the eye; (2) the ciliary body, which is the structure in the eye that secretes the transparent liquid within the front of the eye; and (3) the choroid, which is the layer of blood vessels between the sclera and the retina. Eye with uvea Eye with uvea Eye with uvea Eye with uvea The uvea consists of structures of the eye beneath the white of the eye (sclera). Eye with uvea Eye with uvea The uvea consists of structures of the eye beneath the white of the eye (sclera). Eye with uvea The uvea consists of structures of the eye beneath the white of the eye (sclera). The uvea consists of structures of the eye beneath the white of the eye (sclera). The signs, symptoms and characteristics of uveitis may include: Eye redness. Eye pain. Light sensitivity. Blurred vision. Dark, floating spots in your field of vision (floaters). Decreased vision. Symptoms may occur suddenly and get worse quickly, though in some cases, they develop gradually. They may affect one or both eyes. Occasionally, there are no symptoms, and signs of uveitis are observed on a routine eye exam. The uvea is the middle layer of tissue in the wall of the eye. It consists of the iris, the ciliary body and the choroid. When you look at your eye in the mirror, you will see the white part of the eye (sclera) and the colored part of the eye (iris). The iris is located inside the front of the eye. The ciliary body is a structure behind the iris. The choroid is a layer of blood vessels between the retina and the sclera. The retina lines the inside of the back of the eye, like wallpaper. The inside of the back of the eye is filled with a gel-like liquid called vitreous. The type of uveitis you have depends on which part or parts of the eye are inflamed: Anterior uveitis affects the inside of the front of your eye (between the cornea and the iris) and the ciliary body. It is also called iritis and is the most common type of uveitis. Intermediate uveitis affects the retina and blood vessels just behind the lens (pars plana) as well as the gel in the center of the eye (vitreous). Posterior uveitis affects a layer on the inside of the back of your eye, either the retina or the choroid. Panuveitis occurs when all layers of the uvea are inflamed, from the front to the back of your eye. When to seek medical advice Contact your doctor if you think you have the warning signs of uveitis. He or she may refer you to an eye specialist (ophthalmologist). If you're having significant eye pain and unexpected vision problems, seek immediate medical attention.",1040,Uveitis t heal A white or reddish patch on the inside of your mouth: Loose teeth A growth or lump inside your mouth Mouth pain Ear pain Difficult or painful swallowing,650,Mouth Cancer "stage: Chlamydia trachomatis infections often cause few or no signs and symptoms. Even when signs and symptoms occur, they're often mild, making them easy to overlook. Signs and symptoms of Chlamydia trachomatis infection can include: Painful urination Vaginal discharge in women Discharge from the penis in men Painful sexual intercourse in women Bleeding between periods and after sex in women Testicular pain in men Chlamydia trachomatis can also infect the rectum, either with no signs or symptoms or with rectal pain, discharge or bleeding. You also can get chlamydial eye infections (conjunctivitis) through contact with infected body fluids.",201,Chlamydia "Nickel allergy signs and symptoms include: Rash or bumps on the skin Itching, which may be severe Redness or changes in skin color Dry patches of skin that may resemble a burn Blisters and draining fluid in severe cases",680,Nickel Allergy "Scabies symptoms include: Itching, often severe and usually worse at night Thin, wavy tunnels made up of tiny blisters or bumps on the skin Scabies is often found in the skin folds. But scabies can appear on many parts of the body. In adults and older children, scabies is most often found: Between the fingers and toes In the armpits Around the waist Along the insides of the wrists On the inner elbows On the soles of the feet On the chest Around the nipples Around the belly button Around the genitals In the groin area On the buttocks In infants and young children, common sites of scabies usually include the: Fingers Face, scalp and neck Palms of the hands Soles of the feet If you've had scabies before, symptoms may start within a few days of exposure. If you've never had scabies, it can take as long as six weeks for symptoms to start. You can still spread scabies even if you don't have any symptoms yet.",878,Scabies "MALS: Pain in the upper middle stomach area, which may go away when leaning forward Stomach pain after eating, exercising or changing body position Bloating Diarrhea Fear of eating food due to pain, leading to significant weight loss — usually greater than 20 pounds (9.1 kilograms) Nausea and vomiting",607,Median Arcuate Ligament Syndrome Mals "Mild reaction: Most of the time, bee sting symptoms are minor and include: Instant, sharp burning pain at the sting site A red welt at the sting area Slight swelling around the sting area In most people, the swelling and pain go away within a few hours. Moderate reaction Some people who get stung by a bee or other insect have a bit stronger reaction, with signs and symptoms such as: Extreme redness Swelling at the site of the sting that gradually enlarges over the next day or two Moderate reactions tend to resolve over five to 10 days. Having a moderate reaction doesn't mean you'll have a severe allergic reaction the next time you're stung. But some people develop similar moderate reactions each time they're stung. If this happens to you, talk to your doctor about treatment and prevention, especially if the reaction becomes more severe each time. Severe allergic reaction A severe allergic reaction (anaphylaxis) to bee stings is potentially life-threatening and requires emergency treatment. A small percentage of people who are stung by a bee or other insect quickly develop anaphylaxis. Signs and symptoms of anaphylaxis include: Skin reactions, including hives and itching and flushed or pale skin Difficulty breathing Swelling of the throat and tongue A weak, rapid pulse Nausea, vomiting or diarrhea Dizziness or fainting Loss of consciousness People who have a severe allergic reaction to a bee sting have a 25% to 65% chance of anaphylaxis the next time they're stung. Talk to your doctor or an allergy specialist about prevention measures such as immunotherapy (""allergy shots"") to avoid a similar reaction in case you get stung again. Multiple bee stings Generally, insects such as bees and wasps aren't aggressive and only sting in self-defense. In most cases, this results in one or perhaps a few stings. In some cases a person will disrupt a hive or swarm of bees and get multiple stings. Some types of bees — such as Africanized honeybees — are more likely than are other bees to swarm, stinging in a group. If you get stung more than a dozen times, the accumulation of venom may induce a toxic reaction and make you feel quite sick. Signs and symptoms include: Nausea, vomiting or diarrhea Headache A feeling of spinning (vertigo) Convulsions Fever Dizziness or fainting Multiple stings can be a medical emergency in children, older adults, and people who have heart or breathing problems.",105,Bee Stings "They include: Watery eyes Red eyes A gritty, burning or stinging sensation in the eyes Eyelids that appear greasy Itchy eyelids Red, swollen eyelids Flaking of the skin around the eyes Crusted eyelashes Eyelid sticking More frequent blinking Sensitivity to light Blurred vision that usually improves with blinking",117,Blepharitis "the resulting signs and symptoms may include: Sudden and rapidly intensifying pain in the upper right portion of your abdomen Sudden and rapidly intensifying pain in the center of your abdomen, just below your breastbone Back pain between your shoulder blades Pain in your right shoulder Nausea or vomiting Gallstone pain may last several minutes to a few hours.",397,Gallstones "Pyoderma gangrenosum usually starts with a small, red bump on your skin, which may resemble a spider bite. Within days, this bump can develop into a large, painful open sore. The ulcer usually appears on your legs, but may develop anywhere on your body. Sometimes it appears around surgical sites. If you have several ulcers, they may grow and merge into one larger ulcer.",832,Pyoderma Gangrenosum "Vulva: Vulva Vulva The vulva is the outer part of the female genitalia, including the labia majora, labia minora and clitoris. Vulva Vulva Vulva Vulva The vulva is the outer part of the female genitalia, including the labia majora, labia minora and clitoris. Vulva Vulva The vulva is the outer part of the female genitalia, including the labia majora, labia minora and clitoris. Vulva The vulva is the outer part of the female genitalia, including the labia majora, labia minora and clitoris. The vulva is the outer part of the female genitalia, including the labia majora, labia minora and clitoris. The main vulvodynia symptom is pain in your genital area, which can be characterized as: Burning Soreness Stinging Rawness Painful intercourse (dyspareunia) Throbbing Itching Your pain might be constant or occasional. It might occur only when the sensitive area is touched (provoked). You might feel the pain in your entire vulvar area (generalized), or the pain might be localized to a certain area, such as the opening of your vagina (vestibule). Vulvar tissue might look slightly inflamed or swollen. More often, your vulva appears normal. A similar condition, vestibulodynia, causes pain only when pressure is applied to the area surrounding the entrance to your vagina.",1064,Vulvodynia "Symptoms of sepsis: Symptoms of sepsis may include: Change in mental status. Fast, shallow breathing. Sweating for no clear reason. Feeling lightheaded. Shivering. Symptoms specific to the type of infection, such as painful urination from a urinary tract infection or worsening cough from pneumonia. Symptoms of sepsis are not specific. They can vary from person to person, and sepsis may appear differently in children than in adults. Symptoms of septic shock Sepsis may progress to septic shock. Septic shock is a severe drop in blood pressure. Progression to septic shock raises the risk of death. Symptoms of septic shock include: Not being able to stand up. Strong sleepiness or hard time staying awake. Major change in mental status, such as extreme confusion.",896,Sepsis "They include: Chest pain (angina) or discomfort, often described as aching, pressure, tightness or burning Pain spreading from the chest to the shoulders, arms, upper abdomen, back, neck or jaw Nausea or vomiting Indigestion Shortness of breath (dyspnea) Sudden, heavy sweating (diaphoresis) Lightheadedness, dizziness or fainting Unusual or unexplained fatigue Feeling restless or apprehensive Chest pain or discomfort is the most common symptom. However, signs and symptoms may vary significantly depending on your age, sex and other medical conditions. You're more likely to have signs and symptoms without chest pain or discomfort if you're a woman, older adult or have diabetes.",11,Acute Coronary Syndrome "Other symptoms may include: The inability to control bowel movements (fecal incontinence) Constipation or diarrhea Leaking blood or mucus from the rectum Feeling that your rectum isn't empty after a bowel movement Causes The cause for rectal prolapse is unclear. Though it's a common assumption that rectal prolapse is associated with childbirth, about one-third of women with the condition have never had children. Risk factors Certain factors may increase your risk of developing rectal prolapse, including: Sex. A majority of people with rectal prolapse are women. Age. Rectal prolapse is more common in people over age 50. By Mayo Clinic Staff By Mayo Clinic Staff Rectal prolapse care at Mayo Clinic",841,Rectal Prolapse but sometimes it causes: Pain or fullness in the left upper belly that can spread to the left shoulder A feeling of fullness without eating or after eating a small amount because the spleen is pressing on your stomach Low red blood cells (anemia) Frequent infections Bleeding easily,343,Enlarged Spleen "Angelman syndrome signs and symptoms include: Developmental delays, including no crawling or babbling at 6 to 12 months Intellectual disability No speech or minimal speech Difficulty walking, moving or balancing well Frequent smiling and laughter Happy, excitable personality Sucking or feeding difficulty Trouble going to sleep and staying asleep People who have Angelman syndrome may also show the following features: Seizures, usually beginning between 2 and 3 years of age Stiff or jerky movements Small head size, with flatness in the back of the head Tongue thrusting Hair, skin and eyes that are light in color Unusual behaviors, such as hand flapping and arms uplifted while walking Sleep problems Curved spine (scoliosis)",51,Angelman Syndrome "tachycardia may lead to the following signs and symptoms: Sensation of a racing, pounding heartbeat or flopping in the chest (palpitations) Chest pain Fainting (syncope) Lightheadedness Rapid pulse rate Shortness of breath Some people with tachycardia have no symptoms. The condition may be discovered when a physical exam or heart tests are done for another reason.",966,Tachycardia "A sudden high fever: Low blood pressure Vomiting or diarrhea A rash resembling a sunburn, particularly on your palms and soles Confusion Muscle aches Redness of your eyes, mouth and throat Seizures Headaches",1001,Toxic Shock Syndrome A feeling of fullness in your belly that may make it uncomfortable to eat more than a little at a time: Fatigue Easy bruising Recurring infections Weakness Losing weight without trying,436,Hairy Cell Leukemia "VSD: In general, VSD symptoms in a baby may include: VSD Poor eating Slow or no physical growth (failure to thrive) Fast breathing or breathlessness Easy tiring Whooshing sound when listening to the heart with a stethoscope (heart murmur) Symptoms of a ventricular septal defect in adults may include: Shortness of breath, especially when exercising Whooshing sound when listening to the heart with a stethoscope (heart murmur)",1052,Ventricular Septal Defect "The liver: The liver The liver The liver is your largest internal organ. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach. The liver The liver The liver The liver The liver is your largest internal organ. The liver The liver The liver is your largest internal organ. The liver The liver is your largest internal organ. The liver is your largest internal organ. Most people don't have signs and symptoms in the early stages of primary liver cancer. When signs and symptoms do appear, they may include: Losing weight without trying Loss of appetite Upper abdominal pain Nausea and vomiting General weakness and fatigue Abdominal swelling Yellow discoloration of your skin and the whites of your eyes (jaundice) White, chalky stools",581,Liver Cancer "Signs and symptoms of trichotillomania often include: Repeatedly pulling your hair out, typically from your scalp, eyebrows or eyelashes, but sometimes from other body areas, and sites may vary over time An increasing sense of tension before pulling, or when you try to resist pulling A sense of pleasure or relief after the hair is pulled Noticeable hair loss, such as shortened hair or thinned or bald areas on the scalp or other areas of your body, including sparse or missing eyelashes or eyebrows Preference for specific types of hair, rituals that accompany hair pulling or patterns of hair pulling Biting, chewing or eating pulled-out hair Playing with pulled-out hair or rubbing it across your lips or face Repeatedly trying to stop pulling out your hair or trying to do it less often without success Significant distress or problems at work, school or in social situations related to pulling out your hair Many people who have trichotillomania also pick their skin, bite their nails or chew their lips. Sometimes pulling hairs from pets or dolls or from materials, such as clothes or blankets, may be a sign. Most people with trichotillomania pull hair in private and generally try to hide the disorder from others. For people with trichotillomania, hair pulling can be: Focused. Some people pull their hair intentionally to relieve tension or distress — for example, pulling hair out to get relief from the overwhelming urge to pull hair. Some people may develop elaborate rituals for pulling hair, such as finding just the right hair or biting pulled hairs. Automatic. Some people pull their hair without even realizing they're doing it, such as when they're bored, reading or watching TV. The same person may do both focused and automatic hair pulling, depending on the situation and mood. Certain positions or rituals may trigger hair pulling, such as resting your head on your hand or brushing your hair. Trichotillomania can be related to emotions: Negative emotions. For many people with trichotillomania, hair pulling is a way of dealing with negative or uncomfortable feelings, such as stress, anxiety, tension, boredom, loneliness, fatigue or frustration. Positive feelings. People with trichotillomania often find that pulling out hair feels satisfying and provides a measure of relief. As a result, they continue to pull their hair to maintain these positive feelings. Trichotillomania is a long-term (chronic) disorder. Without treatment, symptoms can vary in severity over time. For example, the hormonal changes of menstruation can worsen symptoms in women. For some people, if not treated, symptoms can come and go for weeks, months or years at a time. Rarely, hair pulling ends within a few years of starting. When to see a doctor If you can't stop pulling out your hair or you feel embarrassed or ashamed by your appearance as a result of your hair pulling, talk to your doctor. Trichotillomania is not just a bad habit, it's a mental health disorder, and it's unlikely to get better without treatment.",1012,Trichotillomania "The main symptom of infertility is not getting pregnant. There may be no other obvious symptoms. Sometimes, women with infertility may have irregular or absent menstrual periods. In some cases, men with infertility may have some signs of hormonal problems, such as changes in hair growth or sexual function. Most couples will eventually conceive, with or without treatment.",521,Infertility among others: Swelling near a bone Bone or joint pain Bone injury or bone break for no clear reason,705,Osteosarcoma The pain associated with a rotator cuff injury may: Be described as a dull ache deep in the shoulder Disturb sleep Make it difficult to comb your hair or reach behind your back Be accompanied by arm weakness Some rotator cuff injuries don't cause pain.,865,Rotator Cuff Injury "Signs and symptoms of: Klinefelter syndrome vary widely among males with the disorder. Many boys with Klinefelter syndrome show few or only mild signs. The condition may go undiagnosed until adulthood or it may never be diagnosed. For others, the condition has a noticeable effect on growth or appearance. Signs and symptoms of Klinefelter syndrome also vary by age. Babies Signs and symptoms may include: Weak muscles Slow motor development — taking longer than average to sit up, crawl and walk Delay in speaking Problems at birth, such as testicles that haven't descended into the scrotum Boys and teenagers Signs and symptoms may include: Taller than average stature Longer legs, shorter torso and broader hips compared with other boys Absent, delayed or incomplete puberty After puberty, less muscle and less facial and body hair compared with other teens Small, firm testicles Small penis Enlarged breast tissue (gynecomastia) Weak bones Low energy levels Tendency to be shy and sensitive Difficulty expressing thoughts and feelings or socializing Problems with reading, writing, spelling or math Men Signs and symptoms may include: Low sperm count or no sperm Small testicles and penis Low sex drive Taller than average height Weak bones Decreased facial and body hair Less muscular compared with other men Enlarged breast tissue Increased belly fat",558,Klinefelter Syndrome "They might include: Enlarged, but painless, lymph nodes Fatigue Fever Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen Night sweats Weight loss Frequent infections",215,Chronic Lymphocytic Leukemia "When to see a doctor: If you think you have PBA, talk to your doctor. If you have a neurological condition, you might already be treated by a doctor who can diagnose PBA. Helpful specialists include neuropsychologists, neurologists and psychiatrists. It's suspected that many cases of pseudobulbar affect go unreported and undiagnosed due to a lack of awareness about the condition.",817,Pseudobulbar Affect "Common categories of specific phobias are a fear of: Situations, such as airplanes, enclosed spaces or going to school Nature, such as thunderstorms or heights Animals or insects, such as dogs or spiders Blood, injection or injury, such as needles, accidents or medical procedures Others, such as choking, vomiting, loud noises or clowns Each specific phobia is referred to by its own term. Examples of more common terms include acrophobia for the fear of heights and claustrophobia for the fear of confined spaces. No matter what specific phobia you have, it's likely to produce these types of reactions: An immediate feeling of intense fear, anxiety and panic when exposed to or even thinking about the source of your fear Awareness that your fears are unreasonable or exaggerated but feeling powerless to control them Worsening anxiety as the situation or object gets closer to you in time or physical proximity Doing everything possible to avoid the object or situation or enduring it with intense anxiety or fear Difficulty functioning normally because of your fear Physical reactions and sensations, including sweating, rapid heartbeat, tight chest or difficulty breathing Feeling nauseated, dizzy or fainting around blood or injuries In children, possibly tantrums, clinging, crying, or refusing to leave a parent's side or approach their fear When to see a doctor When to see a doctor An unreasonable fear can be an annoyance — having to take the stairs instead of an elevator or driving the long way to work instead of taking the freeway, for instance — but it isn't considered a specific phobia unless it seriously disrupts your life. If anxiety negatively affects functioning in work, school or social situations, talk with your doctor or a mental health professional. Childhood fears, such as fear of the dark, of monsters or of being left alone, are common, and most children outgrow them. But if your child has a persistent, excessive fear that interferes with daily functioning at home or school, talk to your child's doctor. Most people can be helped with the right therapy. And therapy tends to be easier when the phobia is addressed right away rather than waiting.",925,Specific Phobias "including: Chin toward shoulder Ear toward shoulder Chin straight up Chin straight down The most common type of twisting associated with cervical dystonia is when your chin is pulled toward your shoulder. Some people experience a combination of abnormal head postures. A jerking motion of the head also may occur. Many people who have cervical dystonia also experience neck pain that can radiate into the shoulders. The disorder can also cause headaches. In some people, the pain from cervical dystonia can be exhausting and disabling. Causes In most people with cervical dystonia, the cause is unknown. Some people who have cervical dystonia have a family history of the disorder. Researchers have found gene mutations associated with cervical dystonia. Cervical dystonia is also sometimes linked to head, neck or shoulder injuries. Risk factors Risk factors for cervical dystonia include: Age. While the disorder can occur in people of any age, it most commonly begins after age 30. Your sex. Women are more likely to develop cervical dystonia than are men. Family history. If a close family member has cervical dystonia or some other type of dystonia, you are at higher risk of developing the disorder. Complications In some cases, the involuntary muscle contractions associated with cervical dystonia can spread to nearby areas of your body. The most common locations include the face, jaw, arms and trunk. People who have cervical dystonia may also develop bone spurs that may reduce the amount of space in the spinal canal. This can cause tingling, numbness and weakness in the arms, hands, legs or feet. By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment Sept. 03, 2021 Print Print Share on: FacebookTwitter Facebook Twitter Show references Dystonias fact sheet. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Dystonias-Fact-Sheet. Accessed July 23, 2019. Frontera WR, et al., eds. Cervical dystonia. In: Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 4th ed. Philadelphia, Pa.: Elsevier; 2019. https://www.clinicalkey.com. Comella C. Classification and evaluation of dystonia. https://www.uptodate.com/contents/search. AskMayoExpert. Cervical dystonia (spasmodic torticollis). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2019. Treatment of dystonia. Botulinum toxins. Facts & Comparisons eAnswers. https://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed July 25, 2019. Show references Dystonias fact sheet. Dystonias fact sheet. Related Associated Procedures Deep brain stimulation Electromyography (EMG) MRI Products & Services Book: Back and Neck Health Related Associated Procedures Deep brain stimulation Electromyography (EMG) MRI Associated Procedures Deep brain stimulation Electromyography (EMG) MRI",185,Cervical Dystonia "Signs and symptoms may include: Being unable to limit the amount of alcohol you drink Wanting to cut down on how much you drink or making unsuccessful attempts to do so Spending a lot of time drinking, getting alcohol or recovering from alcohol use Feeling a strong craving or urge to drink alcohol Failing to fulfill major obligations at work, school or home due to repeated alcohol use Continuing to drink alcohol even though you know it's causing physical, social, work or relationship problems Giving up or reducing social and work activities and hobbies to use alcohol Using alcohol in situations where it's not safe, such as when driving or swimming Developing a tolerance to alcohol so you need more to feel its effect or you have a reduced effect from the same amount Experiencing withdrawal symptoms — such as nausea, sweating and shaking — when you don't drink, or drinking to avoid these symptoms Alcohol use disorder can include periods of being drunk (alcohol intoxication) and symptoms of withdrawal. Alcohol intoxication results as the amount of alcohol in your bloodstream increases. The higher the blood alcohol concentration is, the more likely you are to have bad effects. Alcohol intoxication causes behavior problems and mental changes. These may include inappropriate behavior, unstable moods, poor judgment, slurred speech, problems with attention or memory, and poor coordination. You can also have periods called ""blackouts,"" where you don't remember events. Very high blood alcohol levels can lead to coma, permanent brain damage or even death. Alcohol withdrawal can occur when alcohol use has been heavy and prolonged and is then stopped or greatly reduced. It can occur within several hours to 4 to 5 days later. Signs and symptoms include sweating, rapid heartbeat, hand tremors, problems sleeping, nausea and vomiting, hallucinations, restlessness and agitation, anxiety, and occasionally seizures. Symptoms can be severe enough to impair your ability to function at work or in social situations. What is considered 1 drink? The National Institute on Alcohol Abuse and Alcoholism defines one standard drink as any one of these: 12 ounces (355 milliliters) of regular beer (about 5% alcohol) 8 to 9 ounces (237 to 266 milliliters) of malt liquor (about 7% alcohol) 5 ounces (148 milliliters) of wine (about 12% alcohol) 1.5 ounces (44 milliliters) of hard liquor or distilled spirits (about 40% alcohol)",32,Alcohol Use Disorder "coarse wrinkles: Deep, coarse wrinkles Deep, coarse wrinkles With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck. Deep, coarse wrinkles Deep, coarse wrinkles Deep, coarse wrinkles Deep, coarse wrinkles With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck. Deep, coarse wrinkles Deep, coarse wrinkles With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck. Deep, coarse wrinkles With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck. With repeated sun exposure, wrinkles can become very pronounced and deep, especially on the back of the neck. Wrinkles are the lines and creases that form in your skin. Some wrinkles can become deep crevices or furrows and may be especially noticeable around your eyes, mouth and neck.",1075,Wrinkles "Angiosarcoma that affects the skin: Most often, angiosarcoma occurs in the skin on the head and neck. It often happens on the scalp. Symptoms of this form of angiosarcoma include: A raised area of skin that looks like a bruise A bruise-like lesion that grows larger over time A lesion that may bleed when scratched or bumped Swelling in the skin around the lesion Angiosarcoma that affects organs When angiosarcoma affects organs, such as the liver or the heart, it often causes pain. Other symptoms depend on the location of the angiosarcoma.",53,Angiosarcoma "Asthma signs and symptoms include: Shortness of breath Chest tightness or pain Wheezing when exhaling, which is a common sign of asthma in children Trouble sleeping caused by shortness of breath, coughing or wheezing Coughing or wheezing attacks that are worsened by a respiratory virus, such as a cold or the flu Signs that your asthma is probably worsening include: Asthma signs and symptoms that are more frequent and bothersome Increasing difficulty breathing, as measured with a device used to check how well your lungs are working (peak flow meter) The need to use a quick-relief inhaler more often For some people, asthma signs and symptoms flare up in certain situations: Exercise-induced asthma, which may be worse when the air is cold and dry Occupational asthma, triggered by workplace irritants such as chemical fumes, gases or dust Allergy-induced asthma, triggered by airborne substances, such as pollen, mold spores, cockroach waste, or particles of skin and dried saliva shed by pets (pet dander)",76,Asthma "Symptoms of pinworm infection may include: Itching of the anal or vaginal area Insomnia, irritability, teeth grinding and restlessness Occasional stomach pain and nausea Pinworms often cause no symptoms.",757,Pinworm "Symptoms of bleeding esophageal varices include: Vomiting large amounts of blood. Black, tarry or bloody stools. Lightheadedness due to blood loss. Loss of consciousness in severe cases. Your doctor might suspect esophageal varices if you have signs of liver disease or been diagnosed with liver cirrhosis, including: Yellow coloration of the skin and eyes, known as jaundice. Easy bleeding or bruising. Fluid buildup in the abdomen, called ascites (uh-SY-teez).",354,Esophageal Varices Symptoms of a kidney stone can include: Severe or sudden back pain Pain in the area below the ribs on the back (flank) that doesn't go away Blood in the urine Frequent urge to urinate Pain when urinating Chills or fever,498,Hyperoxaluria "Facial paralysis: Facial paralysis Facial paralysis Facial weakness or paralysis may cause one corner of your mouth to droop. If you're experiencing facial weakness or paralysis, you may have trouble closing the eye on the affected side of your face. Facial paralysis Facial paralysis Facial paralysis Facial paralysis Facial weakness or paralysis may cause one corner of your mouth to droop. Facial paralysis Facial paralysis Facial weakness or paralysis may cause one corner of your mouth to droop. Facial paralysis Facial weakness or paralysis may cause one corner of your mouth to droop. Facial weakness or paralysis may cause one corner of your mouth to droop. The two main signs and symptoms of Ramsay Hunt syndrome are: A painful red rash with fluid-filled blisters on, in and around one ear Facial weakness or paralysis on the same side as the affected ear Usually, the rash and the facial paralysis occur at the same time. Sometimes one can happen before the other. Other times, the rash never occurs. If you have Ramsay Hunt syndrome, you might also experience: Ear pain Hearing loss Ringing in your ears (tinnitus) Difficulty closing one eye A sensation of spinning or moving (vertigo) A change in taste perception or loss of taste Dry mouth and eyes",836,Ramsay Hunt Syndrome "Signs and symptoms include: Skin reactions, including hives and itching and flushed or pale skin Low blood pressure (hypotension) Constriction of the airways and a swollen tongue or throat, which can cause wheezing and trouble breathing A weak and rapid pulse Nausea, vomiting or diarrhea Dizziness or fainting",49,Anaphylaxis "s signs and symptoms may include: Tremor. A tremor, or rhythmic shaking, usually begins in a limb, often your hand or fingers. You may rub your thumb and forefinger back and forth. This is known as a pill-rolling tremor. Your hand may tremble when it's at rest. The shaking may decrease when you are performing tasks. Slowed movement (bradykinesia). Over time, Parkinson's disease may slow your movement, making simple tasks difficult and time-consuming. Your steps may become shorter when you walk. It may be difficult to get out of a chair. You may drag or shuffle your feet as you try to walk. Rigid muscles. Muscle stiffness may occur in any part of your body. The stiff muscles can be painful and limit your range of motion. Impaired posture and balance. Your posture may become stooped. Or you may fall or have balance problems as a result of Parkinson's disease. Loss of automatic movements. You may have a decreased ability to perform unconscious movements, including blinking, smiling or swinging your arms when you walk. Speech changes. You may speak softly, quickly, slur or hesitate before talking. Your speech may be more of a monotone rather than have the usual speech patterns. Writing changes. It may become hard to write, and your writing may appear small.",720,Parkinsons Disease "It frequently begins with the following signs and symptoms: Headache Muscle aches Fever that may be 104 F (40 C) or higher By the second or third day, you'll develop other signs and symptoms that can include: Cough, which might bring up mucus and sometimes blood Shortness of breath Chest pain Gastrointestinal symptoms, such as nausea, vomiting and diarrhea Confusion or other mental changes Although Legionnaires' disease primarily affects the lungs, it occasionally can cause infections in wounds and in other parts of the body, including the heart. A mild form of Legionnaires' disease — known as Pontiac fever — can produce fever, chills, headache and muscle aches. Pontiac fever doesn't infect your lungs, and symptoms usually clear within two to five days.",570,Legionnaires Disease "The main sign of acanthosis nigricans is dark, thick, velvety skin in body folds and creases. It often appears in the armpits, groin and back of the neck. It develops slowly. The affected skin might be itchy, have an odor and develop skin tags.",2,Acanthosis Nigricans "Common signs and symptoms of endometriosis include: Painful periods (dysmenorrhea). Pelvic pain and cramping may begin before and extend several days into a menstrual period. You may also have lower back and abdominal pain. Pain with intercourse. Pain during or after sex is common with endometriosis. Pain with bowel movements or urination. You're most likely to experience these symptoms during a menstrual period. Excessive bleeding. You may experience occasional heavy menstrual periods or bleeding between periods (intermenstrual bleeding). Infertility. Sometimes, endometriosis is first diagnosed in those seeking treatment for infertility. Other signs and symptoms. You may experience fatigue, diarrhea, constipation, bloating or nausea, especially during menstrual periods. The severity of your pain may not be a reliable indicator of the extent of your condition. You could have mild endometriosis with severe pain, or you could have advanced endometriosis with little or no pain. Endometriosis is sometimes mistaken for other conditions that can cause pelvic pain, such as pelvic inflammatory disease (PID) or ovarian cysts. It may be confused with irritable bowel syndrome (IBS), a condition that causes bouts of diarrhea, constipation and abdominal cramping. IBS can accompany endometriosis, which can complicate the diagnosis.",341,Endometriosis "other fever signs and symptoms may include: Sweating Chills and shivering Headache Muscle aches Loss of appetite Irritability Dehydration General weakness Taking a temperature To take a temperature, you can choose from several types of thermometers, including oral, rectal, ear (tympanic) and forehead (temporal artery) thermometers. Oral and rectal thermometers generally provide the most accurate measurement of core body temperature. Ear or forehead thermometers, although convenient, provide less accurate temperature measurements. In infants, a rectal temperature, if doable, is somewhat more accurate. When reporting a temperature to your health care provider, give both the reading and the type of thermometer used.",376,Fever "Foodborne botulism: Symptoms of foodborne botulism typically begin 12 to 36 hours after the toxin gets into your body. But depending on how much toxin you consumed, the start of symptoms may range from a few hours to a few days. Symptoms of foodborne botulism include: Trouble swallowing or speaking Dry mouth Facial weakness on both sides of the face Blurred or double vision Drooping eyelids Trouble breathing Nausea, vomiting and stomach cramps Paralysis Wound botulism Symptoms of wound botulism appear about 10 days after the toxin enters your body. Wound botulism symptoms include: Trouble swallowing or speaking Facial weakness on both sides of the face Blurred or double vision Drooping eyelids Trouble breathing Paralysis The area around the wound may not always appear swollen and show a change of color. Infant botulism Problems generally begin 18 to 36 hours after the toxin enters the baby's body. Symptoms include: Constipation, which is often the first symptom Floppy movements due to muscle weakness and trouble controlling the head Weak cry Irritability Drooling Drooping eyelids Tiredness Trouble sucking or feeding Paralysis Certain symptoms don't typically occur with botulism. For example, botulism doesn't usually raise blood pressure or heart rate or cause fever or confusion. Sometimes, though, wound botulism may cause fever. Iatrogenic botulism In iatrogenic botulism — when the toxin is injected for cosmetic or medical reasons — there have been rare occurrences of serious side effects. These may include headache, facial paralysis, and muscle weakness.",128,Botulism "Symptoms of cough headaches: Begin suddenly with and just after coughing or other types of straining Typically last a few seconds to a few minutes — some can last up to two hours Cause sharp, stabbing, splitting or ""bursting"" pain Usually affect both sides of your head and may be worse in the back of your head May be followed by a dull, aching pain for hours Secondary cough headaches often present with only a cough headache, but you may also experience: Longer lasting headaches Dizziness Unsteadiness Fainting Ringing in the ears or hearing loss Blurred vision or double vision Tremor A cough headache only happens right after coughing. Other headache pain is not a cough headache if you already had a headache when you coughed, or if you have a headache condition such as migraine. For example, people with migraine might find that their headaches get worse when they cough. This is normal, and not a cough headache.",806,Primary Cough Headaches "s possible to have no signs or symptoms with an: Achilles tendon rupture, most people have: The feeling of having been kicked in the calf Pain, possibly severe, and swelling near the heel An inability to bend the foot downward or ""push off"" the injured leg when walking An inability to stand on the toes on the injured leg A popping or snapping sound when the injury occurs When to see your doctor Seek medical advice immediately if you hear a pop in your heel, especially if you can't walk properly afterward.",5,Achilles Tendon Rupture You may have: Chest pain Very fast heartbeat (tachycardia) Dizziness Nausea Shortness of breath,1051,Ventricular Fibrillation "Pseudotumor cerebri signs and symptoms might include: Often severe headaches that might originate behind your eyes A whooshing sound in your head that pulses with your heartbeat Nausea, vomiting or dizziness Vision loss Brief episodes of blindness, lasting a few seconds and affecting one or both eyes Difficulty seeing to the side Double vision Seeing light flashes Neck, shoulder or back pain Sometimes, symptoms that have resolved can recur months or years later.",821,Pseudotumor Cerebri "ADHD: There are three subtypes of ADHD: ADHD Predominantly inattentive. The majority of symptoms fall under inattention. Predominantly hyperactive/impulsive. The majority of symptoms are hyperactive and impulsive. Combined. This is a mix of inattentive symptoms and hyperactive/impulsive symptoms. Inattention A child who shows a pattern of inattention may often: Fail to pay close attention to details or make careless mistakes in schoolwork Have trouble staying focused in tasks or play Appear not to listen, even when spoken to directly Have difficulty following through on instructions and fail to finish schoolwork or chores Have trouble organizing tasks and activities Avoid or dislike tasks that require focused mental effort, such as homework Lose items needed for tasks or activities, for example, toys, school assignments, pencils Be easily distracted Forget to do some daily activities, such as forgetting to do chores Hyperactivity and impulsivity A child who shows a pattern of hyperactive and impulsive symptoms may often: Fidget with or tap his or her hands or feet, or squirm in the seat Have difficulty staying seated in the classroom or in other situations Be on the go, in constant motion Run around or climb in situations when it's not appropriate Have trouble playing or doing an activity quietly Talk too much Blurt out answers, interrupting the questioner Have difficulty waiting for his or her turn Interrupt or intrude on others' conversations, games or activities Typical developmental behavior vs. ADHD Most healthy children are inattentive, hyperactive or impulsive at one time or another. It's typical for preschoolers to have short attention spans and be unable to stick with one activity for long. Even in older children and teenagers, attention span often depends on the level of interest. The same is true of hyperactivity. Young children are naturally energetic — they often are still full of energy long after they've worn their parents out. In addition, some children just naturally have a higher activity level than others do. Children should never be classified as having ADHD just because they're different from their friends or siblings. ADHD Children who have problems in school but get along well at home or with friends are likely struggling with something other than ADHD. The same is true of children who are hyperactive or inattentive at home, but whose schoolwork and friendships remain unaffected.",19,Adhd "Symptoms of ischemic colitis can include: Pain, tenderness or cramping in your belly, which can occur suddenly or happen over time Bright red or maroon blood in your stool or, at times, passage of blood alone without stool A feeling of urgency to move your bowels Diarrhea Nausea The risk of severe complications is higher when you have symptoms on the right side of your belly. This is less commonly seen compared with left-sided colitis. People with right-sided colitis tend to have more underlying medical problems, such as high blood pressure, atrial fibrillation and kidney disease. They more frequently have to undergo surgery and also have a higher risk of death.",539,Ischemic Colitis "KTS: Port-wine stain. This pink to reddish-purple birthmark is caused by extra tiny blood vessels (capillaries) in the top layer of skin. The birthmark often covers part of one leg but can involve any portion of the skin. It may get darker or lighter with age. Vein malformations. These include swollen, twisted veins (varicose veins), usually on the surface of the legs. Deeper malformed veins in the arms, legs, abdomen and pelvis also can occur. There may be spongy tissue filled with small veins in or under the skin. Malformed veins may become more prominent with age. Overgrowth of bones and soft tissue. This begins in infancy and may be limited to one leg, but it can occur in an arm or, rarely, in the trunk or face. This overgrowth of bone and tissue creates a larger and longer extremity. Rarely, there may be fusion of fingers or toes or extra fingers or toes. Lymphatic system malformations. The lymphatic system — part of the immune system that protects against infection and disease and transports lymphatic fluid — can be malformed. Extra lymphatic vessels can be present that don't work properly and can lead to fluid leakage into the tissues and swelling. Other conditions. KTS can also include cataracts, glaucoma, hip dislocation at birth, purple-red skin coloring when cold and blood-clotting problems.",559,Klippel Trenaunay "Or it may come with: Inflamed skin Scratch marks Bumps, spots or blisters Dry, cracked skin Leathery or scaly patches Sometimes itchiness lasts a long time and can be intense. As you rub or scratch the area, it gets itchier. And the more it itches, the more you scratch. Breaking this itch-scratch cycle can be difficult.",540,Itchy Skin "Giant cell arteritis: Giant cell arteritis Giant cell arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. Giant cell arteritis Giant cell arteritis Giant cell arteritis Giant cell arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. Giant cell arteritis Giant cell arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. Giant cell arteritis Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. Giant cell arteritis causes inflammation of certain arteries, especially those near the temples. The most common symptoms of giant cell arteritis are head pain and tenderness — often severe — that usually affects both temples. Head pain can progressively worsen, come and go, or subside temporarily. Generally, signs and symptoms of giant cell arteritis include: Persistent, severe head pain, usually in your temple area Scalp tenderness Jaw pain when you chew or open your mouth wide Fever Fatigue Unintended weight loss Vision loss or double vision, particularly in people who also have jaw pain Sudden, permanent loss of vision in one eye Pain and stiffness in the neck, shoulders or hips are common symptoms of a related disorder, polymyalgia rheumatica. About 50 percent of people with giant cell arteritis also have polymyalgia rheumatica.",414,Giant Cell Arteritis "General signs and symptoms caused by brain tumors may include: Headache or pressure in the head that is worse in the morning. Headaches that happen more often and seem more severe. Headaches that are sometimes described as tension headaches or migraines. Nausea or vomiting. Eye problems, such as blurry vision, seeing double or losing sight on the sides of your vision. Losing feeling or movement in an arm or a leg. Trouble with balance. Speech problems. Feeling very tired. Confusion in everyday matters. Memory problems. Having trouble following simple commands. Personality or behavior changes. Seizures, especially if there is no history of seizures. Hearing problems. Dizziness or a sense that the world is spinning, also called vertigo. Feeling very hungry and gaining weight. Brain tumors that aren't cancerous tend to cause symptoms that develop slowly. Noncancerous brain tumors also are called benign brain tumors. They might cause subtle symptoms that you don't notice at first. The symptoms might get worse over months or years. Cancerous brain tumors cause symptoms that get worse quickly. Cancerous brain tumors also are called brain cancers or malignant brain tumors. They cause symptoms that come on suddenly. They get worse in a matter of days or weeks. Brain tumor headaches Headaches are the most common symptom of brain tumors. Headaches happen in about half of people with brain tumors. Headaches can happen if a growing brain tumor presses on healthy cells around it. Or a brain tumor can cause swelling in the brain that increases pressure in the head and leads to a headache. Headache pain caused by brain tumors is often worse when you wake up in the morning. But it can happen at any time. Some people have headaches that wake them from sleep. Brain tumor headaches tend to cause pain that's worse when coughing or straining. People with brain tumors most often report that the headache feels like a tension headache. Some people say the headache feels like a migraine. Brain tumors in the back of the head might cause a headache with neck pain. If the brain tumor happens in the front of the head, the headache might feel like eye pain or sinus pain. Brain tumor symptoms by location Brain lobes Brain lobes Brain lobes Each side of your brain contains four lobes. The frontal lobe is important for cognitive functions and control of voluntary movement or activity. The parietal lobe processes information about temperature, taste, touch and movement, while the occipital lobe is primarily responsible for vision. The temporal lobe processes memories, integrating them with sensations of taste, sound, sight and touch. Brain lobes Brain lobes Brain lobes Brain lobes Each side of your brain contains four lobes. Brain lobes Brain lobes Each side of your brain contains four lobes. Brain lobes Each side of your brain contains four lobes. Each side of your brain contains four lobes. The main part of the brain is called the cerebrum. Brain tumors in different parts of the cerebrum might cause different symptoms. Brain tumors in the front of the brain. The frontal lobes are in the front of the brain. They control thinking and movement. Frontal lobe brain tumors might cause balance problems and trouble walking. There might be personality changes, such as forgetfulness and lack of interest in usual activities. Sometimes family members notice that the person with the brain tumor seems different. Brain tumors in the middle of the brain. The parietal lobes are in the upper middle part of the brain. They help process information about touch, taste, smell, vision and hearing. Parietal lobe brain tumors can cause problems related to the senses. Examples include vision problems and hearing problems. Brain tumors in the back of the brain. The occipital lobes are in the back of the brain. They control vision. Occipital lobe brain tumors can cause vision loss. Brain tumors in the lower part of the brain. The temporal lobes are on the sides of the brain. They process memories and senses. Temporal lobe brain tumors can cause memory problems. They might cause someone to see, taste or smell something that isn't there. Sometimes the taste or smell is unpleasant or unusual.",134,Brain Tumor "shakes or spasms that are: Sudden Brief Involuntary Shock-like Variable in intensity and frequency Occurring in one part of the body or all over the body Sometimes severe enough to interfere with eating, speaking or walking",664,Myoclonus "they might include: Whooshing sound (heart murmur) when a doctor is listening to the heart with a stethoscope Chest pain Abdominal swelling (more common with advanced tricuspid regurgitation) Fatigue Shortness of breath, particularly when active or lying down Swelling of your ankles and feet Dizziness Fainting Irregular heartbeat",452,Heart Valve Disease "Signs and symptoms that affect body movement and function may include: Weakness or paralysis Abnormal movement, such as tremors or difficulty walking Loss of balance Difficulty swallowing or feeling ""a lump in the throat"" Seizures or episodes of shaking and apparent loss of consciousness (nonepileptic seizures) Episodes of unresponsiveness Signs and symptoms that affect the senses may include: Numbness or loss of the touch sensation Speech problems, such as the inability to speak or slurred speech Vision problems, such as double vision or blindness Hearing problems or deafness Cognitive difficulties involving memory and concentration",247,Conversion Disorder "RSV: Congested or runny nose Dry cough Low-grade fever Sore throat Sneezing Headache In severe cases RSV infection can spread to the lower respiratory tract, causing pneumonia or bronchiolitis — inflammation of the small airway passages entering the lungs. Signs and symptoms may include: RSV Fever Severe cough Wheezing — a high-pitched noise that's usually heard on breathing out (exhaling) Rapid breathing or difficulty breathing — the person may prefer to sit up rather than lie down Bluish color of the skin due to lack of oxygen (cyanosis) Infants are most severely affected by RSV. Signs and symptoms of severe RSV infection in infants include: RSV RSV Short, shallow and rapid breathing Struggling to breathe — chest muscles and skin pull inward with each breath Cough Poor feeding Unusual tiredness (lethargy) Irritability Most children and adults recover in one to two weeks, although some might have repeated wheezing. Severe or life-threatening infection requiring a hospital stay may occur in premature infants or in anyone who has chronic heart or lung problems. RSV and COVID-19 Because RSV and coronavirus disease 2019 (COVID-19) are both types of respiratory viruses, some symptoms of RSV and COVID-19 can be similar. In children, COVID-19 often results in mild symptoms such as fever, runny nose and cough. For adults with COVID-19, symptoms may be more severe and may include trouble breathing. RSV RSV COVID-19 COVID-19 COVID-19 Having RSV may lower immunity and increase the risk of getting COVID-19 — for kids and adults. And these infections may occur together, which can worsen the severity of COVID-19 illness. RSV COVID-19 COVID-19 If you have symptoms of a respiratory illness, your doctor may recommend testing for COVID-19.",848,Respiratory Syncytial Virus "Symptoms may include: Swelling or a lump under your skin Pain, tingling or numbness Weakness or loss of function in the affected area Dizziness or loss of balance Causes The cause of benign peripheral nerve tumors usually isn't known. Some are passed down in families. The most common type of benign peripheral nerve tumor is a schwannoma. A schwannoma typically starts in a single bundle inside the main nerve, shifting the rest of the nerve. Another common type is a neurofibroma. A neurofibroma also often forms inside the nerve. Sometimes it grows from several nerve bundles. Perineuriomas are rare and can grow from inside or outside the nerve. Tumors outside a nerve can cause problems when they press on the nerve. Other benign tumors that form outside nerves are soft lumps of slow-growing fat cells called lipomas and ganglion cysts. By Mayo Clinic Staff By Mayo Clinic Staff Benign peripheral nerve tumor care at Mayo Clinic",744,Peripheral Nerve Tumors Benign "Nearsightedness signs or symptoms may include: Blurry vision when looking at distant objects The need to squint or partially close the eyelids to see clearly Headaches Eyestrain Children may have difficulty seeing things on white boards or screen projections in the classroom. Younger children might not express difficulty seeing, but they may have the following behaviors that suggest difficulty seeing: Persistently squint Seem unaware of distant objects Blink excessively Rub their eyes frequently Sit close to the television Adults with myopia may notice difficulty reading street signs or signs in a store. Some people may experience blurry vision in dim light, as with nighttime driving, even if they see clearly in daylight. This condition is called night myopia.",672,Nearsightedness "CTE CTE CTE: Cognitive impairment Difficulty thinking (cognitive impairment) Memory loss Problems with planning, organization and carrying out tasks (executive function) Behavioral changes Impulsive behavior Aggression Mood disorders Depression or apathy Emotional instability Substance misuse Suicidal thoughts or behavior Motor symptoms Parkinsonism Motor neuron disease CTE symptoms don't develop right after a head injury, but experts believe that they might develop over years or decades after repeated head trauma. Experts currently believe that CTE symptoms appear in two forms. In early life between the late 20s and early 30s, the first form of CTE may cause mental health and behavioral issues including depression, anxiety, impulsivity and aggression. The second form of CTE is thought to cause symptoms later in life, around age 60. These signs and symptoms include memory and thinking problems that are likely to progress to dementia. CTE CTE CTE CTE The full list of signs to look for in people with CTE at autopsy is still unknown. It is unclear what kind of symptoms, if any, CTE may cause during life. Little is known right now about how CTE progresses.",219,Chronic Traumatic Encephalopathy "you may experience some of the following signs and symptoms: Immediate, throbbing pain Pain that increases with activity and decreases with rest Swelling Bruising Tenderness Deformity Difficulty in walking or bearing weight",141,Broken Foot "Signs and symptoms of antiphospholipid syndrome can include: Blood clots in legs (DVT). Signs of a DVT include pain, swelling and redness. These clots can travel to the lungs (pulmonary embolism). Repeated miscarriages or stillbirths. Other complications of pregnancy include dangerously high blood pressure (preeclampsia) and premature delivery. Stroke. A stroke can occur in a young person who has antiphospholipid syndrome but no known risk factors for cardiovascular diseases. Transient ischemic attack (TIA). Similar to a stroke, a TIA usually lasts only a few minutes and causes no permanent damage. Rash. Some people develop a red rash with a lacy, net-like pattern. Less common signs and symptoms include: Neurological symptoms. Chronic headaches, including migraines; dementia and seizures are possible when a blood clot blocks blood flow to parts of the brain. Cardiovascular disease. Antiphospholipid syndrome can damage heart valves. Low blood platelet counts (thrombocytopenia). This decrease in blood cells needed for clotting can cause episodes of bleeding, particularly from the nose and gums. Bleeding into the skin will appear as patches of small red spots.",59,Antiphospholipid Syndrome "including: Breathlessness with activity or even at rest Swelling of the legs, ankles and feet Bloating of the abdomen due to fluid buildup Cough while lying down Difficulty lying flat to sleep Fatigue Heartbeats that feel rapid, pounding or fluttering Chest discomfort or pressure Dizziness, lightheadedness and fainting Signs and symptoms tend to get worse unless treated. In some people, the condition worsens quickly; in others, it might not worsen for a long time.",172,Cardiomyopathy "Signs and symptoms may include: Diarrhea, often with blood or pus Rectal bleeding — passing small amount of blood with stool Abdominal pain and cramping Rectal pain Urgency to defecate Inability to defecate despite urgency Weight loss Fatigue Fever In children, failure to grow Most people with ulcerative colitis have mild to moderate symptoms. The course of ulcerative colitis may vary, with some people having long periods when it goes away. This is called remission. Types Health care providers often classify ulcerative colitis according to its location. Symptoms of each type often overlap. Types of ulcerative colitis include: Ulcerative proctitis. Inflammation is confined to the area closest to the anus, also called the rectum. Rectal bleeding may be the only sign of the disease. Proctosigmoiditis. Inflammation involves the rectum and sigmoid colon — the lower end of the colon. Symptoms include bloody diarrhea, abdominal cramps and pain, and an inability to move the bowels despite the urge to do so. This is called tenesmus. Left-sided colitis. Inflammation extends from the rectum up through the sigmoid and descending portions of the colon. Symptoms include bloody diarrhea, abdominal cramping and pain on the left side, and urgency to defecate. Pancolitis. This type often affects the entire colon and causes bouts of bloody diarrhea that may be severe, abdominal cramps and pain, fatigue, and significant weight loss.",1028,Ulcerative Colitis "Symptoms of REM sleep behavior disorder may include: Movement, such as kicking, punching, arm flailing or jumping from bed, in response to action-filled or violent dreams, such as being chased or defending yourself from an attack Noises, such as talking, laughing, shouting, emotional outcries or even cursing Being able to recall the dream if you awaken during the episode",846,Rem Sleep Behavior Disorder "Bladder cancer signs and symptoms may include: Blood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test Frequent urination Painful urination Back pain",113,Bladder Cancer "Symptoms of trigger finger may progress from mild to severe and include: Finger stiffness, particularly in the morning. A popping or clicking sensation as the finger moves. Tenderness or a bump in the palm at the base of the affected finger. Finger catching or locking in a bent position, which suddenly pops straight. Finger locked in a bent position. Trigger finger can affect any finger, including the thumb. More than one finger may be affected at a time, and both hands might be involved. Triggering is usually worse in the morning.",1016,Trigger Finger "A soft bulge of tissue in the vagina that might come through the opening of the vagina: Trouble having a bowel movement Feeling pressure or fullness in the rectum A feeling that the rectum has not completely emptied after a bowel movement Sexual concerns, such as feeling embarrassed or sensing looseness in the tone of the vaginal tissue Many women with posterior vaginal prolapse also have prolapse of other pelvic organs, such as the bladder or uterus. A surgeon can evaluate the prolapse and talk about options for surgery to fix it.",843,Rectocele "Emotional and behavioral symptoms: Signs and symptoms of social anxiety disorder can include constant: Fear of situations in which you may be judged negatively Worry about embarrassing or humiliating yourself Intense fear of interacting or talking with strangers Fear that others will notice that you look anxious Fear of physical symptoms that may cause you embarrassment, such as blushing, sweating, trembling or having a shaky voice Avoidance of doing things or speaking to people out of fear of embarrassment Avoidance of situations where you might be the center of attention Anxiety in anticipation of a feared activity or event Intense fear or anxiety during social situations Analysis of your performance and identification of flaws in your interactions after a social situation Expectation of the worst possible consequences from a negative experience during a social situation For children, anxiety about interacting with adults or peers may be shown by crying, having temper tantrums, clinging to parents or refusing to speak in social situations. Performance type of social anxiety disorder is when you experience intense fear and anxiety during speaking or performing in public but not in other types of more general social situations. Physical symptoms Physical signs and symptoms can sometimes accompany social anxiety disorder and may include: Blushing Fast heartbeat Trembling Sweating Upset stomach or nausea Trouble catching your breath Dizziness or lightheadedness Feeling that your mind has gone blank Muscle tension Avoiding common social situations Common, everyday experiences may be hard to endure when you have social anxiety disorder, including: Interacting with unfamiliar people or strangers Attending parties or social gatherings Going to work or school Starting conversations Making eye contact Dating Entering a room in which people are already seated Returning items to a store Eating in front of others Using a public restroom Social anxiety disorder symptoms can change over time. They may flare up if you're facing a lot of changes, stress or demands in your life. Although avoiding situations that produce anxiety may make you feel better in the short term, your anxiety is likely to continue over the long term if you don't get treatment. When to see a doctor See your doctor or a mental health professional if you fear and avoid normal social situations because they cause embarrassment, worry or panic.",920,Social Anxiety Disorder "Most people who have: Paget's disease of bone have no symptoms. When symptoms occur, the most common complaint is bone pain. Because this disease causes your body to generate new bone faster than normal, the rapid remodeling produces bone that's less organized and weaker than normal bone, which can lead to bone pain, deformities and fractures. The disease might affect only one or two areas of your body or might be widespread. Your signs and symptoms, if any, will depend on the affected part of your body. Pelvis. Paget's disease of bone in the pelvis can cause hip pain. Skull. An overgrowth of bone in the skull can cause hearing loss or headaches. Spine. If your spine is affected, nerve roots can become compressed. This can cause pain, tingling and numbness in an arm or leg. Leg. As the bones weaken, they may bend — causing you to become bowlegged. Enlarged and misshapen bones in your legs can put extra stress on nearby joints, which may cause osteoarthritis in your knee or hip.",710,Pagets Disease Of Bone "Common symptoms include: Shortness of breath. This symptom usually appears suddenly. Trouble catching your breath happens even when resting and gets worse with physical activity. Chest pain. You may feel like you're having a heart attack. The pain is often sharp and felt when you breathe in deeply. The pain can stop you from being able to take a deep breath. You also may feel it when you cough, bend or lean over. Fainting. You may pass out if your heart rate or blood pressure drops suddenly. This is called syncope. Other symptoms that can occur with pulmonary embolism include: A cough that may include bloody or blood-streaked mucus Rapid or irregular heartbeat Lightheadedness or dizziness Excessive sweating Fever Leg pain or swelling, or both, usually in the back of the lower leg Clammy or discolored skin, called cyanosis",827,Pulmonary Embolism "Signs and symptoms that occur during an episode of ventricular tachycardia are due to a lack of oxygen and may include: Chest pain (angina) Dizziness Pounding heartbeat (palpitations) Lightheadedness Shortness of breath Ventricular tachycardia may go away on its own within 30 seconds (nonsustained V-tach) or last more than 30 seconds (sustained V-tach or VT). Brief episodes may not cause any symptoms. But sustained VT can cause serious problems, including: V-tach V-tach VT VT Fainting Loss of consciousness Cardiac arrest (sudden death)",1053,Ventricular Tachycardia "Foot drop makes it difficult to lift the front part of the foot, so it might drag on the floor when you walk. To help the foot clear the floor, a person with foot drop may raise the thigh more than usual when walking, as though climbing stairs. This unusual kind of walking, called steppage gait, might cause the foot to slap down onto the floor with each step. In some cases, the skin on the top of the foot and toes feels numb. Depending on the cause, foot drop can affect one or both feet.",387,Foot Drop These may include: Fatigue Shortness of breath Dizziness Pale or yellowish skin Irregular heartbeats Weight loss Numbness or tingling in the hands and feet Muscle weakness Personality changes Unsteady movements Mental confusion or forgetfulness,1059,Vitamin Deficiency Anemia "Symptoms may include: Joint pain. Abdominal pain. Fatigue. Weakness. Diabetes. Loss of sex drive. Impotence. Heart failure. Liver failure. Bronze or gray skin color. Memory fog. When symptoms typically appear The most common type of hemochromatosis is present at birth. But most people don't experience symptoms until later in life — usually after age 40 in men and after age 60 in women. Women are more likely to develop symptoms after menopause, when they no longer lose iron with menstruation and pregnancy.",459,Hemochromatosis "Appearance: The lesions may appear as: Lacy, white, raised patches of tissues Red, swollen, tender patches of tissues Open sores Location These lesions may appear on the: Inside of the cheeks, the most common location Gums Tongue Inner tissues of the lips Palate Pain or discomfort The white, lacy patches may not cause discomfort when they appear on the inside of the cheeks. However, symptoms accompanying red, swollen patches and open sores may include: Burning sensation or pain Sensitivity to hot, acidic or spicy foods Bleeding and irritation with tooth brushing Inflammation of the gums (gingivitis) Painful, thickened patches on the tongue Discomfort when speaking, chewing or swallowing Other types of lichen planus If you have oral lichen planus, you may have lichen planus lesions affecting other parts of your body. Skin. Lesions usually appear as purplish, flat-topped bumps that are often itchy. Genitals. Lesions on the female genitalia often cause pain or burning and discomfort with intercourse. The lesions are usually red and eroded and occasionally appear as white areas. Lesions can also occur on male genitalia. Ears. Lichen planus of the ears can lead to hearing loss. Scalp. When skin lesions appear on the scalp, they may cause temporary or permanent hair loss. Nails. Though rare, lichen planus of the toenails or fingernails may result in ridges on the nails, thinning or splitting of nails, and temporary or permanent nail loss. Eyes. Rarely, lichen planus may involve the mucous membrane surfaces of the eyes, and can cause scarring and blindness. Esophagus. Lichen planus of the esophagus is rare, but when it occurs, it may result in a narrowing of the esophagus or the formation of tightened, ringlike bands in the esophagus that can make swallowing difficult.",696,Oral Lichen Planus "B: Symptoms of MEN 2 depend on the type of tumor. People who have MEN 2B have a unique appearance. They may have bumps on the tongue, lips and eyes. They tend to be tall and thin with long arms and legs. Following are symptoms that may be related to each tumor type. MEN 2 MEN 2B Medullary thyroid cancer: Lumps in the throat or neck Trouble breathing or swallowing Hoarseness Diarrhea Parathyroid hyperplasia, also known as primary hyperparathyroidism: Muscle and joint pain Constipation Fatigue Memory problems Kidney stones Adrenal tumors, also known as pheochromocytoma: High blood pressure Rapid heart rate Anxiety Headaches Symptoms may be caused by a thyroid tumor pressing on tissues around it or by the release of too many hormones in the body. Some people who have medullary thyroid cancer may have no symptoms.",611,Men 2 A breast lump: Bloody nipple discharge DCIS is usually found on a mammogram and appears as small clusters of calcifications that have irregular shapes and sizes.,268,Dcis "Bottom line: There is no magic number to define low sex drive. It varies among women. Symptoms of low sex drive in women include: Having no interest in any type of sexual activity, including masturbation Never or only seldom having sexual fantasies or thoughts Being concerned by your lack of sexual activity or fantasies",587,Low Sex Drive In Women Polycystic kidney disease symptoms can include: High blood pressure Back or side pain Blood in your urine A feeling of fullness in your abdomen Increased size of your abdomen due to enlarged kidneys Headaches Kidney stones Kidney failure Urinary tract or kidney infections,771,Polycystic Kidney Disease "Burning stomach pain: Feeling of fullness, bloating or belching Intolerance to fatty foods Heartburn Nausea The most common peptic ulcer symptom is burning stomach pain. Stomach acid makes the pain worse, as does having an empty stomach. The pain can often be relieved by eating certain foods that buffer stomach acid or by taking an acid-reducing medication, but then it may come back. The pain may be worse between meals and at night. Many people with peptic ulcers don't even have symptoms. Less often, ulcers may cause severe signs or symptoms such as: Vomiting or vomiting blood — which may appear red or black Dark blood in stools, or stools that are black or tarry Trouble breathing Feeling faint Nausea or vomiting Unexplained weight loss Appetite changes",734,Peptic Ulcer "including the: Legs Chest Armpits Beard or mustache Eyelashes or eyebrows, more commonly in children",824,Pubic Lice Crabs "include: Fatigue Lump or area of thickening that can be felt under the skin Weight changes, including unintended loss or gain Skin changes, such as yellowing, darkening or redness of the skin, sores that won't heal, or changes to existing moles Changes in bowel or bladder habits Persistent cough or trouble breathing Difficulty swallowing Hoarseness Persistent indigestion or discomfort after eating Persistent, unexplained muscle or joint pain Persistent, unexplained fevers or night sweats Unexplained bleeding or bruising",165,Cancer "COPD: Signs and symptoms of COPD may include: COPD Shortness of breath, especially during physical activities Wheezing Chest tightness A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish Frequent respiratory infections Lack of energy Unintended weight loss (in later stages) Swelling in ankles, feet or legs People with COPD are also likely to experience episodes called exacerbations, during which their symptoms become worse than the usual day-to-day variation and persist for at least several days.",248,Copd "Signs and symptoms can include: Anemia. Sickle cells break apart easily and die. Red blood cells usually live for about 120 days before they need to be replaced. But sickle cells typically die in 10 to 20 days, leaving a shortage of red blood cells (anemia). Without enough red blood cells, the body can't get enough oxygen and this causes fatigue. Episodes of pain. Periodic episodes of extreme pain, called pain crises, are a major symptom of sickle cell anemia. Pain develops when sickle-shaped red blood cells block blood flow through tiny blood vessels to your chest, abdomen and joints. The pain varies in intensity and can last for a few hours to a few days. Some people have only a few pain crises a year. Others have a dozen or more a year. A severe pain crisis requires a hospital stay. Some adolescents and adults with sickle cell anemia also have chronic pain, which can result from bone and joint damage, ulcers, and other causes. Swelling of hands and feet. The swelling is caused by sickle-shaped red blood cells blocking blood circulation in the hands and feet. Frequent infections. Sickle cells can damage the spleen, increasing vulnerability to infections. Infants and children with sickle cell anemia commonly receive vaccinations and antibiotics to prevent potentially life-threatening infections, such as pneumonia. Delayed growth or puberty. Red blood cells provide the body with the oxygen and nutrients needed for growth. A shortage of healthy red blood cells can slow growth in infants and children and delay puberty in teenagers. Vision problems. Tiny blood vessels that supply the eyes can become plugged with sickle cells. This can damage the retina — the portion of the eye that processes visual images — and lead to vision problems.",907,Sickle Cell Anemia "days and may include: Mild fever of 102 F (38.9 C) or lower Headache Stuffy or runny nose Red, itchy eyes Enlarged, tender lymph nodes at the base of the skull, the back of the neck and behind the ears A fine, pink rash that begins on the face and quickly spreads to the trunk and then the arms and legs, before disappearing in the same order Aching joints, especially in young women",867,Rubella "Signs or symptoms of gas or gas pains include: Burping Passing gas Pain, cramps or a knotted feeling in your abdomen A feeling of fullness or pressure in your abdomen (bloating) An observable increase in the size of your abdomen (distention) Burping is normal, particularly during or right after a meal. Most people pass gas up to 20 times a day. Therefore, while having gas may be inconvenient or embarrassing, burping and passing gas are rarely by themselves a sign of a medical problem.",400,Gas And Gas Pains "dAVF: Aggressive dAVF symptoms can result either from bleeding in the brain (intracerebral hemorrhage) or from neurological effects of nonhemorrhaging neurological deficits (NHNDs). Aggressive dAVF symptoms dAVF Bleeding in the brain often causes a sudden headache with varying degrees of neurological disability related to the location and size of the hemorrhage. By contrast, an NHND usually develops more gradually, over days to weeks, and typically produces symptoms related to its location. NHND These aggressive symptoms can include: Difficulty walking, falls Seizures Speech or language issues Facial pain Dementia Parkinsonism Coordination issues Burning or prickling sensations Weakness Apathy Failure to thrive Symptoms related to increased pressure such as headaches, nausea and vomiting. Other dAVF symptoms can include hearing issues, such as a bruit behind the ear, also known as pulsatile tinnitus. Other symptoms include vision problems such as: Other dAVF symptoms dAVF Visual deterioration Eye bulge Swelling in the eye lining Eye-related palsies Cavernous sinus syndrome. In rare cases, progressive dementia may occur due to venous hypertension.",317,Dural Arteriovenous Fistulas signs and symptoms may include: Vaginal dryness Vaginal burning Vaginal discharge Genital itching Burning with urination Urgency with urination Frequent urination Recurrent urinary tract infections Urinary incontinence Light bleeding after intercourse Discomfort with intercourse Decreased vaginal lubrication during sexual activity Shortening and tightening of the vaginal canal,1042,Vaginal Atrophy "Common signs and symptoms of central sleep apnea include: Observed episodes of not breathing or abnormal breathing patterns during sleep Abrupt awakenings accompanied by shortness of breath Difficulty staying asleep (insomnia) Excessive daytime sleepiness (hypersomnia) Difficulty concentrating Mood changes Morning headaches Snoring Although snoring indicates some degree of airflow obstruction, snoring can also be heard in the presence of central sleep apnea. However, snoring may not be as prominent with central sleep apnea as it is with obstructive sleep apnea.",182,Central Sleep Apnea "A lump that can be felt through the skin: Pain Changes in bowel habits, such as new and persistent constipation or diarrhea Frequent urination Cough Fever Night sweats Losing weight without trying",170,Carcinoma Unknown Primary "Additional signs and symptoms of progressive supranuclear palsy vary and may mimic those of: Parkinson's disease and dementia. They generally get worse over time and may include: Stiffness (especially of the neck) and awkward movements Falling, especially falling backward Slow or slurred speech Problems with swallowing, which may cause gagging or choking Sensitivity to bright light Sleep disturbances Loss of interest in pleasurable activities Impulsive behavior, or laughing or crying for no reason Difficulties with reasoning, problem-solving and decision-making Depression and anxiety A surprised or frightened facial expression, resulting from rigid facial muscles Dizziness",813,Progressive Supranuclear Palsy "persistent urge to urinate A burning sensation when urinating: The need to pass small amounts of urine frequently Cloudy urine Fever Pain in your side (flank) or abdomen A UTI may be difficult to diagnose in children, who may have only nonspecific signs and symptoms. Signs and symptoms in infants with a UTI may also include: UTI UTI An unexplained fever Lack of appetite Irritability As your child gets older, untreated vesicoureteral reflux can lead to: Bed-wetting Constipation or loss of control over bowel movements High blood pressure Protein in urine Another indication of vesicoureteral reflux, which may be detected before birth by sonogram, is swelling of the kidneys or the urine-collecting structures of one or both kidneys (hydronephrosis) in the fetus, caused by the backup of urine into the kidneys.",1056,Vesicoureteral Reflux "is defined as experiencing any of these in a significant way: Delayed orgasm Absence of orgasm Fewer orgasms Less-intense orgasms Anorgasmia can also be: Lifelong, if you've never had an orgasm Acquired, if you have new problems with having orgasms Situational, if you have problems with orgasm only in certain situations, with certain kinds of stimulation or with certain partners Generalized, if you have problems with orgasm in any situation Women who don't always reach orgasm during sexual encounters may not find it distressing. In that case, the lack of an orgasm is not considered a disorder.",56,Anorgasmia "Visual signs and symptoms: Most people who have migraine with aura develop temporary visual signs and symptoms, which tend to start in the center of the field of vision and spread outward. These might include: Blind spots (scotomas), which are sometimes outlined by simple geometric designs Zigzag lines that gradually float across your field of vision Shimmering spots or stars Changes in vision or vision loss Flashes of light Other disturbances Other temporary disturbances sometimes associated with migraine aura include: Numbness, typically felt as tingling in one hand or on one side of your face that may spread slowly along a limb Speech or language difficulty Muscle weakness",632,Migraine With Aura "Possible signs and symptoms of salmonella infection include: Diarrhea Stomach (abdominal) cramps Fever Nausea Vomiting Chills Headache Blood in the stool Signs and symptoms of salmonella infection generally last a few days to a week. Diarrhea may last up to 10 days, but it may take several months before bowels return to usual stool habits. A few varieties of salmonella bacteria result in typhoid fever, a sometimes deadly disease that is more common in developing countries.",874,Salmonella "A few people with high blood pressure may have: Headaches Shortness of breath Nosebleeds However, these symptoms aren't specific. They usually don't occur until high blood pressure has reached a severe or life-threatening stage.",476,High Blood Pressure "Bedbug bites: Bedbug bites Bedbug bites It can be difficult to tell bedbug bites from other types of insect bites. However, they are typically itchy, and they may appear clustered or lined up in rough rows. Bedbug bites Bedbug bites Bedbug bites Bedbug bites It can be difficult to tell bedbug bites from other types of insect bites. Bedbug bites Bedbug bites It can be difficult to tell bedbug bites from other types of insect bites. Bedbug bites It can be difficult to tell bedbug bites from other types of insect bites. It can be difficult to tell bedbug bites from other types of insect bites. Symptoms of bedbug bites are similar to symptoms of other insect bites and rashes. Bedbug bites are usually: Inflamed spots, often with a darker spot in the middle Itchy Arranged in a rough line or in a cluster Located on the face, neck, arms and hands Some people have no reaction to bedbug bites, while others experience an allergic reaction that can include severe itching, blisters or hives.",104,Bedbugs "ODD ODD: Emotional and behavioral symptoms of ODD generally last at least six months. They include angry and irritable mood, argumentative and defiant behavior, and hurtful and revengeful behavior. ODD Angry and irritable mood Angry and irritable mood Often and easily loses temper. Is frequently touchy and easily annoyed by others. Is often angry and resentful. Argumentative and defiant behavior Argumentative and defiant behavior Often argues with adults or people in authority. Often actively defies or refuses to follow adults' requests or rules. Often annoys or upsets people on purpose. Often blames others for their own mistakes or misbehavior. Hurtful and revengeful behavior Hurtful and revengeful behavior Says mean and hateful things when upset. Tries to hurt the feelings of others and seeks revenge, also called being vindictive. Has shown vindictive behavior at least twice in the past six months. Severity Severity ODD can be mild, moderate or severe: ODD Mild. Symptoms occur only in one setting, such as only at home, school, work or with peers. Moderate. Some symptoms occur in at least two settings. Severe. Some symptoms occur in three or more settings. For some children, symptoms may first be seen only at home. But with time, problem behavior also may happen in other settings, such as school, social activities and with friends.",694,Oppositional Defiant Disorder "Tinea versicolor signs and symptoms include: Patches of skin discoloration, usually on the back, chest, neck and upper arms, which may appear lighter or darker than usual Mild itching Scaling",989,Tinea Versicolor "Common myocarditis symptoms include: Chest pain Fatigue Swelling of the legs, ankles and feet Rapid or irregular heartbeat (arrhythmias) Shortness of breath, at rest or during activity Light-headedness or feeling like you might faint Flu-like symptoms such as headache, body aches, joint pain, fever or sore throat Sometimes, myocarditis symptoms are like a heart attack. If you are having unexplained chest pain and shortness of breath, seek emergency medical help. Myocarditis in children When children develop myocarditis, symptoms may include: Breathing difficulties Chest pain Fainting Fever Rapid breathing Rapid or irregular heart rhythms (arrhythmias)",663,Myocarditis "Vocal cords open and closed: Vocal cords open and closed Vocal cords open and closed Vocal cords open when you breathe and then close to produce sound when vibrating together. Vocal cords open and closed Vocal cords open and closed Vocal cords open and closed Vocal cords open and closed Vocal cords open when you breathe and then close to produce sound when vibrating together. Vocal cords open and closed Vocal cords open and closed Vocal cords open when you breathe and then close to produce sound when vibrating together. Vocal cords open and closed Vocal cords open when you breathe and then close to produce sound when vibrating together. Vocal cords open when you breathe and then close to produce sound when vibrating together. Your vocal cords are two flexible bands of muscle tissue that sit at the entrance to the windpipe (trachea). When you speak, the bands come together and vibrate to make sound. The rest of the time, the vocal cords are relaxed in an open position so that you can breathe. In most cases of vocal cord paralysis, only one vocal cord is paralyzed. Paralysis of both of your vocal cords is a rare but serious condition. This can cause difficulties with speech and significant problems with breathing and swallowing. Signs and symptoms of vocal cord paralysis may include: A breathy quality to the voice Hoarseness Noisy breathing Shortness of breath Loss of vocal pitch Choking or coughing while swallowing food, drink or saliva The need to take frequent breaths while speaking Inability to speak loudly Loss of your gag reflex Ineffective coughing Frequent throat clearing",1061,Vocal Cord Paralysis the affected joint might: Feel achy or stiff Hurt more when you move it or press on it Look swollen and red,162,Bursitis "you may leak urine when you: Cough or sneeze Laugh Bend over Lift something heavy Exercise Have sex You may not leak urine every time you do one of these things. But, any activity that puts pressure on your bladder can make involuntary urine loss more likely, particularly when your bladder is full.",946,Stress Incontinence "Minor canker sores: Minor canker sores are the most common and: Are usually small Are oval shaped with a red edge Heal without scarring in one to two weeks Major canker sores Major canker sores are less common and: Are larger and deeper than minor canker sores Are usually round with defined borders, but may have irregular edges when very large Can be extremely painful May take up to six weeks to heal and can leave extensive scarring Herpetiform canker sores Herpetiform canker sores are uncommon and usually develop later in life, but they're not caused by herpes virus infection. These canker sores: Are pinpoint size Often occur in clusters of 10 to 100 sores, but may merge into one large ulcer Have irregular edges Heal without scarring in one to two weeks",166,Canker Sore Signs and symptoms of nasal and paranasal tumors can include: Difficulty breathing through your nose Loss of the sense of smell Nosebleeds Discharge from your nose Facial swelling or pain Watery eyes A sore or lesion on the roof of your mouth Vision problems A lump in your neck Difficulty opening your mouth,669,Nasal Paranasal Tumors "Children: Signs and symptoms common in children include: Ear pain, especially when lying down Tugging or pulling at an ear Trouble sleeping Crying more than usual Fussiness Trouble hearing or responding to sounds Loss of balance Fever of 100 F (38 C) or higher Drainage of fluid from the ear Headache Loss of appetite Adults Common signs and symptoms in adults include: Ear pain Drainage of fluid from the ear Trouble hearing",326,Ear Infections "Infant or young child: Dry mouth and tongue No tears when crying No wet diapers for three hours Sunken eyes, cheeks Sunken soft spot on top of skull Listlessness or irritability Adult Extreme thirst Less frequent urination Dark-colored urine Fatigue Dizziness Confusion When to see a doctor Call your family doctor if you or a loved one: Has had diarrhea for 24 hours or more Is irritable or disoriented and much sleepier or less active than usual Can't keep down fluids Has bloody or black stool",271,Dehydration "HHT: Nosebleeds, sometimes on a daily basis and often starting in childhood Lacy red vessels or tiny red spots, particularly on the lips, face, fingertips, tongue and inside surfaces of the mouth Iron deficiency anemia Shortness of breath Headaches Seizures",471,Hht "Facial paralysis: Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial weakness or paralysis may cause one corner of your mouth to droop, and you may have trouble retaining saliva on that side of your mouth. The condition may also make it difficult to close the eye on the affected side of your face. Facial paralysis Facial paralysis Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial paralysis Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Facial paralysis The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. The nerve that controls your facial muscles passes through a narrow corridor of bone on its way to your face. Signs and symptoms of Bell's palsy come on suddenly and may include: Rapid onset of mild weakness to total paralysis on one side of your face — occurring within hours to days Facial droop and difficulty making facial expressions, such as closing your eye or smiling Drooling Pain around the jaw or in or behind your ear on the affected side Increased sensitivity to sound on the affected side Headache A loss of taste Changes in the amount of tears and saliva you produce In rare cases, Bell's palsy can affect the nerves on both sides of your face.",107,Bells Palsy A lump or swelling on or near your jaw or in your neck or mouth: Numbness in part of your face Muscle weakness on one side of your face Persistent pain in the area of a salivary gland Difficulty swallowing Trouble opening your mouth widely,873,Salivary Gland Cancer A frequent or continuous feeling that you need to have a bowel movement: Rectal bleeding Passing mucus through your rectum Rectal pain Pain on the left side of your abdomen A feeling of fullness in your rectum Diarrhea Pain with bowel movements,811,Proctitis "A painless lump or thickening in your breast tissue: Changes to the skin covering your breast, such as dimpling, puckering, redness or scaling Changes to your nipple, such as redness or scaling, or a nipple that begins to turn inward Discharge from your nipple",597,Male Breast Cancer include: Moderate fever Chills Headache Muscles aches or pains General feeling of being unwell Joint pain Nausea Vomiting Diarrhea Loss of appetite Additional signs and symptoms associated with ehrlichiosis but rarely with anaplasmosis include: Confusion or changes in mental state Rash Some people may be infected and not develop symptoms.,334,Ehrlichiosis "Muscle spasms might: Begin in a single area, such as your leg, neck or arm. Focal dystonia that begins after age 21 usually starts in the neck, arm or face. It tends to remain focal or become segmental. Occur during a specific action, such as writing by hand. Worsen with stress, fatigue or anxiety. Become more noticeable over time. Areas of the body that can be affected include: Neck (cervical dystonia). Contractions cause your head to twist and turn to one side, or pull forward or backward, sometimes causing pain. Eyelids. Rapid blinking or spasms cause your eyes to close (blepharospasms) and make it difficult for you to see. Spasms usually aren't painful but might increase when you're in bright light, reading, watching TV, under stress or interacting with people. Your eyes might feel dry, gritty or sensitive to light. Jaw or tongue (oromandibular dystonia). You might experience slurred speech, drooling, and difficulty chewing or swallowing. Oromandibular dystonia can be painful and often occurs in combination with cervical dystonia or blepharospasm. Voice box and vocal cords (laryngeal dystonia). You might have a tight or whispering voice. Hand and forearm. Some types of dystonia occur only while you do a repetitive activity, such as writing (writer's dystonia) or playing a specific musical instrument (musician's dystonia). Symptoms usually don't happen when your arm is at rest.",324,Dystonia Signs and symptoms might include: Blue- or gray-toned skin (cyanosis) Fast breathing or shortness of breath Easily tiring or being fatigued Feeding problems,825,Pulmonary Atresia "Symptoms include: Grayish-blue color of the lips and gums (cyanosis) Rapid, difficult breathing Poor feeding Cold hands and feet Weak pulse Being unusually drowsy or inactive If the natural connections between the heart's left and right sides (foramen ovale and ductus arteriosus) are allowed to close in the first few days of life in babies with hypoplastic left heart syndrome, they can go into shock and possibly die. Signs of shock include: Cool, clammy skin that can be pale or lips that can be bluish-gray A weak and rapid pulse Breathing that may be slow and shallow or very rapid Dull eyes that seem to stare A baby in shock might be conscious or unconscious.",508,Hypoplastic Left Heart Syndrome "The factor V: Leiden mutation does not itself cause any symptoms. Since factor V Leiden is a risk for developing blood clots in the leg or lungs, the first indication that you have the disorder may be the development of an abnormal blood clot. Some clots do no damage and disappear on their own. Others can be life-threatening. Symptoms of a blood clot depend on what part of your body is affected. A clot in a deep vein This is known as deep vein thrombosis (DVT), which most commonly occurs in the legs. A DVT may not cause any symptoms. If signs and symptoms do occur, they can include: Pain Swelling Redness Warmth A clot that travels to your lungs Known as a pulmonary embolism, this occurs when a portion of a DVT breaks free and travels through the right side of your heart to your lung, where it blocks blood flow. This can be a life-threatening situation. Signs and symptoms may include: Sudden shortness of breath Chest pain when breathing in A cough that produces bloody or blood-streaked sputum Rapid heartbeat",365,Factor V Leiden "They may include: Shortness of breath, especially while lying down Swelling of the legs Chest pain, often when exercising Sensation of rapid, fluttering or pounding heartbeats, called palpitations Fainting or a feeling of lightheadedness",568,Left Ventricular Hypertrophy "Smallpox: Smallpox Smallpox These are smallpox sores on the skin. This photograph was taken in Bangladesh in 1974. Smallpox Smallpox Smallpox Smallpox These are smallpox sores on the skin. Smallpox Smallpox These are smallpox sores on the skin. Smallpox These are smallpox sores on the skin. These are smallpox sores on the skin. The first symptoms of smallpox usually appear 12 to 14 days after you're exposed to the smallpox virus. However, the virus can be in your body from 7 to 19 days before you look or feel sick. This time is called the incubation period. After the incubation period, sudden flu-like symptoms occur. These include: Fever Muscle aches Headache Severe fatigue Severe back pain Vomiting, sometimes A few days later, flat, red spots appear on the body. They may start in the mouth and on the tongue and then spread to the skin. The face, arms and legs are often affected first, followed by the torso, hands and feet. Within a day or two, many of the spots turn into small blisters filled with clear fluid. Later, the blisters fill with pus. These sores are called pustules. Scabs form 8 to 9 days later and eventually fall off, leaving deep, pitted scars. Smallpox can be spread from person to person when the rash appears and until the scabs fall off.",918,Smallpox "Symptoms of cholecystitis may include: Severe pain in your upper right or center abdomen Pain that spreads to your right shoulder or back Tenderness over your abdomen when it's touched Nausea Vomiting Fever Cholecystitis symptoms often occur after a meal, particularly a large or fatty one.",203,Cholecystitis "Signs and symptoms of systemic mastocytosis may include: Flushing, itching or hives Abdominal pain, diarrhea, nausea or vomiting Anemia or bleeding disorders Bone and muscle pain Enlarged liver, spleen or lymph nodes Depression, mood changes or problems concentrating The mast cells are triggered to produce substances that cause inflammation and symptoms. People have different triggers, but the most common ones include: Alcohol Skin irritation Spicy foods Exercise Insect stings Certain medications When to see a doctor When to see a doctor Talk to your doctor if you have problems with flushing or hives, or if you have concerns about the signs or symptoms listed above. Causes Most cases of systemic mastocytosis are caused by a random change (mutation) in the KIT gene. Typically this flaw in the KIT gene is not inherited. Too many mast cells are produced and build up in tissues and body organs, releasing substances such as histamine, leukotrienes and cytokines that cause inflammation and symptoms. Complications Complications of systemic mastocytosis can include: Anaphylactic reaction. This severe allergic reaction includes signs and symptoms such as rapid heartbeat, fainting, loss of consciousness and shock. If you have a severe allergic reaction, you may need an injection of epinephrine. Blood disorders. These can include anemia and poor blood clotting. Peptic ulcer disease. Chronic stomach irritation can lead to ulcers and bleeding in your digestive tract. Reduced bone density. Because systemic mastocytosis can affect your bones and bone marrow, you may be at risk of bone problems, such as osteoporosis. Organ failure. A buildup of mast cells in body organs can cause inflammation and damage to the organ. By Mayo Clinic Staff By Mayo Clinic Staff Systemic mastocytosis care at Mayo Clinic",965,Systemic Mastocytosis "Signs and symptoms of black hairy tongue include: Black discoloration of the tongue, although the color may be brown, tan, green, yellow or white A hairy or furry appearance of the tongue Altered taste or metallic taste in your mouth Bad breath (halitosis) Gagging or tickling sensation, if the overgrowth of the papillae is excessive",112,Black Hairy Tongue "Swimmer's itch symptoms include an itchy rash that looks like pimples or blisters. Symptoms may begin within minutes or as long as two days after swimming or wading in contaminated water. Usually the rash affects skin that's not covered by swimsuits, wetsuits or waders. Your sensitivity to swimmer's itch can increase each time you're exposed to the parasites that cause it.",960,Swimmers Itch "Symptoms include: Pain that's often worsened by holding the head in one place for long periods, such as when driving or working at a computer Muscle tightness and spasms Decreased ability to move the head Headache",673,Neck Pain "External hemorrhoids: These are under the skin around your anus. Signs and symptoms might include: Itching or irritation in your anal region Pain or discomfort Swelling around your anus Bleeding Internal hemorrhoids Internal hemorrhoids lie inside the rectum. You usually can't see or feel them, and they rarely cause discomfort. But straining or irritation when passing stool can cause: Painless bleeding during bowel movements. You might notice small amounts of bright red blood on your toilet tissue or in the toilet. A hemorrhoid to push through the anal opening (prolapsed or protruding hemorrhoid), resulting in pain and irritation. Thrombosed hemorrhoids If blood pools in an external hemorrhoid and forms a clot (thrombus), it can result in: Severe pain Swelling Inflammation A hard lump near your anus",462,Hemorrhoids "Symptoms of: Eisenmenger syndrome include: Blue or gray skin color due to low oxygen levels (cyanosis) Chest pain or tightness Coughing up blood Dizziness or fainting Easily tiring and shortness of breath with activity Headaches Large, rounded fingernails or toenails (clubbing) Numbness or tingling in fingers or toes Shortness of breath while at rest Skipped or racing heartbeats (palpitations)",335,Eisenmenger Syndrome "Not all children carrying extra pounds are overweight. Some children have larger than average body frames. And children normally carry different amounts of body fat at the various stages of development. So you might not know by how your child looks if weight is a health concern. The body mass index (BMI), which provides a guideline of weight in relation to height, is the accepted measure of overweight and obesity. Your child's doctor can use growth charts, the BMI and, if necessary, other tests to help you figure out if your child's weight could pose health problems.",199,Childhood Obesity "the most misused prescription drugs are: Opioids used to treat pain, such as medicines containing oxycodone (Oxycontin, Percocet) and those containing hydrocodone (Norco) Anti-anxiety medicines, sedatives and hypnotics used to treat anxiety and sleep disorders, such as alprazolam (Xanax), diazepam (Valium) and zolpidem (Ambien) Stimulants used to treat attention-deficit/hyperactivity disorder (ADHD) and certain sleep disorders, such as methylphenidate (Ritalin, Concerta, others), dextroamphetamine-amphetamine (Adderall XR, Mydayis) and dextroamphetamine (Dexedrine) Signs and symptoms of prescription drug abuse Opioids Constipation Nausea Feeling high Slowed breathing rate Drowsiness Confusion Poor coordination Increased dose needed for pain relief Worsening or increased sensitivity to pain with higher doses Anti-anxiety medicines and sedatives Drowsiness Confusion Unsteady walking Slurred speech Poor concentration Dizziness Problems with memory Slowed breathing Stimulants Increased alertness Feeling high Irregular heartbeat High blood pressure High body temperature Reduced appetite Insomnia Agitation Anxiety Paranoia Other signs Forging, stealing or selling prescriptions Taking higher doses than prescribed Being hostile or having mood swings Sleeping less or more Making poor decisions Being unusually energetic, high or revved up Being drowsy Requesting early refills or continually ""losing"" prescriptions, so more prescriptions must be written Trying to get prescriptions from more than one prescriber",802,Prescription Drug Abuse "Signs and symptoms of frontal lobe seizures might include: Head and eye movement to one side Complete or partial unresponsiveness or difficulty speaking Explosive screams, including profanities, or laughter Abnormal body posturing, such as one arm extending while the other flexes, as if the person is posing like a fencer Repetitive movements, such as rocking, bicycle pedaling or pelvic thrusting",388,Frontal Lobe Seizures "Symptoms of heart disease in the blood vessels: Coronary artery disease is a common heart condition that affects the major blood vessels that supply the heart muscle. Cholesterol deposits (plaques) in the heart arteries are usually the cause of coronary artery disease. The buildup of these plaques is called atherosclerosis (ath-ur-o-skluh-ROE-sis). Atherosclerosis reduces blood flow to the heart and other parts of the body. It can lead to a heart attack, chest pain (angina) or stroke. Coronary artery disease symptoms may be different for men and women. For instance, men are more likely to have chest pain. Women are more likely to have other symptoms along with chest discomfort, such as shortness of breath, nausea and extreme fatigue. Symptoms of coronary artery disease can include: Chest pain, chest tightness, chest pressure and chest discomfort (angina) Shortness of breath Pain in the neck, jaw, throat, upper belly area or back Pain, numbness, weakness or coldness in the legs or arms if the blood vessels in those body areas are narrowed You might not be diagnosed with coronary artery disease until you have a heart attack, angina, stroke or heart failure. It's important to watch for heart symptoms and discuss concerns with your health care provider. Heart (cardiovascular) disease can sometimes be found early with regular health checkups. What is coronary artery disease? A Mayo Clinic cardiologist explains. Stephen Kopecky, M.D., talks about the risk factors, symptoms and treatment of coronary artery disease (CAD). Learn how lifestyle changes can lower your risk. Show transcript for video What is coronary artery disease? {Music playing} Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: I'm Dr. Stephen Kopecky, a cardiologist at Mayo Clinic. In this video, we'll cover the basics of coronary artery disease. What is it? Who gets it? The symptoms, diagnosis and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. Coronary artery disease, also called CAD, is a condition that affects your heart. It is the most common heart disease in the United States. CAD happens when coronary arteries struggle to supply the heart with enough blood, oxygen and nutrients. Cholesterol deposits, or plaques, are almost always to blame. These buildups narrow your arteries, decreasing blood flow to your heart. This can cause chest pain, shortness of breath or even a heart attack. CAD typically takes a long time to develop. So often, patients don't know that they have it until there's a problem. But there are ways to prevent coronary artery disease, and ways to know if you're at risk and ways to treat it. Anyone can develop CAD. It begins when fats, cholesterols and other substances gather along the walls of your arteries. This process is called atherosclerosis. It's typically no cause for concern. However, too much buildup can lead to a blockage, obstructing blood flow. There are a number of risk factors, common red flags, that can contribute to this and ultimately lead to coronary artery disease. First, getting older can mean more damaged and narrowed arteries. Second, men are generally at a greater risk. But the risk for women increases after menopause. Existing health conditions matter, too. High blood pressure can thicken your arteries, narrowing your blood flow. High cholesterol levels can increase the rate of plaque buildup. Diabetes is also associated with higher risk, as is being overweight. Your lifestyle plays a large role as well. Physical inactivity, long periods of unrelieved stress in your life, an unhealthy diet and smoking can all increase your risk. And finally, family history. If a close relative was diagnosed at an early age with heart disease, you're at a greater risk. All these factors together can paint a picture of your risk for developing CAD. What are the symptoms? When coronary arteries become narrow, the heart doesn't get enough oxygen-rich blood. Remember, unlike most pumps, the heart has to pump its own energy supply. It's working harder with less. And you may begin to notice these signs and symptoms of pressure or tightness in your chest. This pain is called angina. It may feel like somebody is standing on your chest. When your heart can't pump enough blood to meet your body's needs, you might develop shortness of breath or extreme fatigue during activities. And if an artery becomes totally blocked, it leads to a heart attack. Classic signs and symptoms of a heart attack include crushing, substernal chest pain, pain in your shoulders or arms, shortness of breath, and sweating. However, many heart attacks have minimal or no symptoms and are found later during routine testing. How is it diagnosed? Diagnosing CAD starts by talking to your doctor. They'll be able to look at your medical history, do a physical exam and order routine blood work. Depending on that, they may suggest one or more of the following tests: an electrocardiogram or ECG, an echocardiogram or soundwave test of the heart, stress test, cardiac catheterization and angiogram, or a cardiac CT scan. How is it treated? Treating coronary artery disease usually means making changes to your lifestyle. This might be eating healthier foods, exercising regularly, losing excess weight, reducing stress or quitting smoking. The good news is these changes can do a lot to improve your outlook. Living a healthier life translates to having healthier arteries. When necessary, treatment could involve drugs like aspirin, cholesterol-modifying medications, beta-blockers, or certain medical procedures like angioplasty or coronary artery bypass surgery. What now? Discovering you have coronary artery disease can be overwhelming. But be encouraged. There are things you can do to manage and live with this condition. Reducing cholesterol, lowering blood pressure, quitting tobacco, eating healthier, exercising and managing your stress can make a world of difference. Better heart health starts by educating yourself. So don't be afraid to seek out information and ask your doctors about coronary artery disease. If you'd like to learn even more about this condition, watch our other related videos or visit Mayoclinic.org. We wish you well. {Music playing} {Music playing} Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: I'm Dr. Stephen Kopecky, M.D., Cardiovascular Disease, Mayo Clinic: Coronary artery disease, also called CAD, is a condition that affects your heart. CAD CAD Who gets it? CAD CAD What are the symptoms? CAD CT How is it treated? Heart disease symptoms caused by irregular heartbeats (heart arrhythmias) The heart may beat too quickly, too slowly or irregularly. Heart arrhythmia symptoms can include: Chest pain or discomfort Dizziness Fainting (syncope) or near fainting Fluttering in the chest Lightheadedness Racing heartbeat (tachycardia) Shortness of breath Slow heartbeat (bradycardia) Heart disease symptoms caused by congenital heart defects Serious congenital heart defects usually are noticed soon after birth. Congenital heart defect symptoms in children could include: Pale gray or blue skin or lips (cyanosis) Swelling in the legs, belly area or areas around the eyes In an infant, shortness of breath during feedings, leading to poor weight gain Less-serious congenital heart defects are often not diagnosed until later in childhood or during adulthood. Symptoms of congenital heart defects that usually aren't immediately life-threatening include: Easily getting short of breath during exercise or activity Easily tiring during exercise or activity Swelling of the hands, ankles or feet Heart disease symptoms caused by diseased heart muscle (cardiomyopathy) Early stages of cardiomyopathy may not cause noticeable symptoms. As the condition worsens, symptoms may include: Dizziness, lightheadedness and fainting Fatigue Feeling short of breath during activity or at rest Feeling short of breath at night when trying to sleep or waking up short of breath Irregular heartbeats that feel rapid, pounding or fluttering Swollen legs, ankles or feet Heart disease symptoms caused by heart valve problems (valvular heart disease) The heart has four valves — the aortic, mitral, pulmonary and tricuspid valves. They open and close to move blood through the heart. Many things can damage the heart valves. A heart valve may become narrowed (stenosis), leaky (regurgitation or insufficiency) or close improperly (prolapse). Valvular heart disease is also called heart valve disease. Depending on which valve isn't working properly, heart valve disease symptoms generally include: Chest pain Fainting (syncope) Fatigue Irregular heartbeat Shortness of breath Swollen feet or ankles Endocarditis is an infection that affects the heart valves and inner lining of the heart chambers and heart valves (endocardium). Endocarditis symptoms can include: Dry or persistent cough Fever Heartbeat changes Shortness of breath Skin rashes or unusual spots Swelling of the legs or belly area Weakness or fatigue",448,Heart Disease "you might notice: Deep, constant pain in the belly area or side of the belly (abdomen) Back pain A pulse near the bellybutton",1,Abdominal Aortic Aneurysm "The most obvious sign of a subconjunctival hemorrhage is a bright red patch on the white (sclera) of your eye. Despite its bloody appearance, a subconjunctival hemorrhage looks worse than it is and should cause no change in your vision, discharge or pain. Your only discomfort may be a scratchy feeling on the surface of the eye.",951,Subconjunctival Hemorrhage "Complete defect: The condition affects all of the heart's chambers. Symptoms of a complete atrioventricular canal defect usually develop in the first weeks of life. Symptoms are generally similar to those of heart failure. They may include: Blue or gray skin color due to low oxygen levels Difficulty breathing or rapid breathing Excessive sweating Fatigue Irregular or rapid heartbeat Lack of appetite Poor weight gain Swelling in the legs, ankles and feet Wheezing Partial defect The condition affects only the two upper heart chambers. Symptoms of a partial atrioventricular canal defect may not appear until early adulthood. The symptoms may be due to complications such as heart valve problems, high blood pressure in the lungs or heart failure. Symptoms may include: Fatigue and weakness Nausea and lack of appetite Persistent cough or wheezing Rapid or irregular heartbeat, also called an arrhythmia Reduced ability to exercise Shortness of breath Swelling in the legs, ankles and feet Chest pressure or pain",85,Atrioventricular Canal Defect High cholesterol has no symptoms. A blood test is the only way to detect if you have it.,475,High Blood Cholesterol "pressure or pain: Low back pain that eases when you lie down A soft bulge of tissue in your vagina Vaginal discomfort and painful intercourse (dyspareunia) Many women with small bowel prolapse also experience prolapse of other pelvic organs, such as the bladder, uterus or rectum.",344,Enterocele "Alcohol poisoning signs and symptoms include: Confusion Vomiting Seizures Slow breathing (less than eight breaths a minute) Irregular breathing (a gap of more than 10 seconds between breaths) Blue-tinged skin or pale skin Low body temperature (hypothermia) Passing out (unconsciousness) and can't be awakened When to see a doctor It's not necessary to have all the above signs or symptoms before you seek medical help. A person with alcohol poisoning who is unconscious or can't be awakened is at risk of dying. Alcohol poisoning is an emergency If you suspect that someone has alcohol poisoning — even if you don't see the classic signs and symptoms — seek immediate medical care. Here's what to do: Call 911 or your local emergency number immediately. Never assume the person will sleep off alcohol poisoning. Be prepared to provide information. If you know, be sure to tell hospital or emergency personnel the kind and amount of alcohol the person drank, and when. Don't leave an unconscious person alone. Because alcohol poisoning affects the way the gag reflex works, someone with alcohol poisoning may choke on his or her own vomit and not be able to breathe. While waiting for help, don't try to make the person vomit because he or she could choke. Help a person who is vomiting. Try to keep him or her sitting up. If the person must lie down, make sure to turn his or her head to the side — this helps prevent choking. Try to keep the person awake to prevent loss of consciousness. Don't be afraid to get help It can be difficult to decide if you think someone is drunk enough to warrant medical intervention, but it's best to err on the side of caution. You may worry about the consequences for yourself or your friend or loved one, particularly if you're underage. But the consequences of not getting the right help in time can be far more serious.",31,Alcohol Poisoning "In this severe type of spina bifida: The spinal canal remains open along several vertebrae in the lower or middle back Both the membranes and the spinal cord or nerves protrude at birth, forming a sac Tissues and nerves usually are exposed, though sometimes skin covers the sac",928,Spina Bifida "can include: Facial redness (flushing) Red, itchy skin bumps (hives) Worsening of pre-existing asthma Runny or stuffy nose Low blood pressure Nausea and vomiting Diarrhea",30,Alcohol Intolerance "persistent urge to urinate: Pain or a burning feeling when urinating Passing frequent, small amounts of urine Blood in the urine (hematuria) Passing cloudy or strong-smelling urine Pelvic discomfort A feeling of pressure in the area below your belly button (abdomen) Low-grade fever In young children, new episodes of accidental daytime wetting also may be a sign of a urinary tract infection (UTI). Nighttime bed-wetting on its own isn't likely to happen because of a UTI.",265,Cystitis "A cough: Changes in your voice, such as hoarseness or not speaking clearly Difficulty swallowing Ear pain A lump or sore that doesn't heal A sore throat Weight loss",982,Throat Cancer "but may include: Memory loss (amnesia) of certain time periods, events, people and personal information A sense of being detached from yourself and your emotions A perception of the people and things around you as distorted and unreal A blurred sense of identity Significant stress or problems in your relationships, work or other important areas of your life Inability to cope well with emotional or professional stress Mental health problems, such as depression, anxiety, and suicidal thoughts and behaviors There are three major dissociative disorders defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), published by the American Psychiatric Association: Dissociative amnesia. The main symptom is memory loss that's more severe than normal forgetfulness and that can't be explained by a medical condition. You can't recall information about yourself or events and people in your life, especially from a traumatic time. Dissociative amnesia can be specific to events in a certain time, such as intense combat, or more rarely, can involve complete loss of memory about yourself. It may sometimes involve travel or confused wandering away from your life (dissociative fugue). An episode of amnesia usually occurs suddenly and may last minutes, hours, or rarely, months or years. Dissociative identity disorder. Formerly known as multiple personality disorder, this disorder is characterized by ""switching"" to alternate identities. You may feel the presence of two or more people talking or living inside your head, and you may feel as though you're possessed by other identities. Each identity may have a unique name, personal history and characteristics, including obvious differences in voice, gender, mannerisms and even such physical qualities as the need for eyeglasses. There also are differences in how familiar each identity is with the others. People with dissociative identity disorder typically also have dissociative amnesia and often have dissociative fugue. Depersonalization-derealization disorder. This involves an ongoing or episodic sense of detachment or being outside yourself — observing your actions, feelings, thoughts and self from a distance as though watching a movie (depersonalization). Other people and things around you may feel detached and foggy or dreamlike, time may be slowed down or sped up, and the world may seem unreal (derealization). You may experience depersonalization, derealization or both. Symptoms, which can be profoundly distressing, may last only a few moments or come and go over many years. When to see a doctor Some people with dissociative disorders present in a crisis with traumatic flashbacks that are overwhelming or associated with unsafe behavior. People with these symptoms should be seen in an emergency room. If you or a loved one has less urgent symptoms that may indicate a dissociative disorder, call your doctor. Suicidal thoughts or behavior If you have thoughts of hurting yourself or someone else, call 911 or your local emergency number immediately, go to an emergency room, or confide in a trusted relative or friend. Or contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline, available 24 hours a day, seven days a week. Or use the Lifeline Chat. Services are free and confidential.",300,Dissociative Disorders "Parvovirus symptoms in children: Early signs and symptoms of parvovirus infection in children may include: Fever Upset stomach Headache Runny nose Distinctive facial rash Several days after the appearance of early symptoms, a distinctive bright red rash may appear on your child's face — usually on both cheeks. Eventually it may spread to the arms, trunk, thighs and buttocks, where the rash has a pink, lacy, slightly raised appearance. The rash may be itchy, especially on the soles of the feet. Generally, the rash occurs near the end of the illness. It's possible to mistake the rash for other viral rashes or a medicine-related rash. The rash may come and go for up to three weeks, becoming more visible when your child is exposed to extreme temperatures or spends time in the sun. Parvovirus symptoms in adults Adults don't usually develop the slapped-cheek rash. Instead, the most noticeable symptom of parvovirus infection in adults is joint soreness, lasting days to weeks. Joints most commonly affected are the hands, wrists, knees and ankles.",721,Parvovirus Infection "Insomnia symptoms may include: Difficulty falling asleep at night Waking up during the night Waking up too early Not feeling well-rested after a night's sleep Daytime tiredness or sleepiness Irritability, depression or anxiety Difficulty paying attention, focusing on tasks or remembering Increased errors or accidents Ongoing worries about sleep When to see a doctor If insomnia makes it hard for you to function during the day, see your doctor to identify the cause of your sleep problem and how it can be treated. If your doctor thinks you could have a sleep disorder, you might be referred to a sleep center for special testing.",527,Insomnia you might feel: Pain or discomfort in the affected testicle Heaviness in the testicle with the spermatocele Fullness behind and above the testicle,926,Spermatocele Signs and symptoms of a retractile testicle include: The testicle may be moved by hand from the groin into the scrotum and won't immediately retreat to the groin. The testicle might spontaneously appear in the scrotum and remain there for a time. The testicle might spontaneously disappear again for a time. Retractile testicle is different from undescended testicle (cryptorchidism). An undescended testicle is one that never entered the scrotum.,853,Retractile Testicle "Vaginitis signs and symptoms can include: Change in color, odor or amount of discharge from your vagina Vaginal itching or irritation Pain during sex Painful urination Light vaginal bleeding or spotting If you have vaginal discharge, the characteristics of the discharge might indicate the type of vaginitis you have. Examples include: Bacterial vaginosis. You might develop a grayish-white, foul-smelling discharge. The odor, often described as a fishy odor, might be more obvious after sex. Yeast infection. The main symptom is itching, but you might have a thick white discharge that resembles cottage cheese. Trichomoniasis. An infection called trichomoniasis (trik-o-moe-NIE-uh-sis) can cause a greenish-yellow, sometimes frothy discharge.",1044,Vaginitis "Signs and symptoms of lupus nephritis include: Blood in your urine Foamy urine (due to excess protein in urine) High blood pressure Swelling in your hands, ankles or feet High levels of a waste product called creatinine in your blood",591,Lupus Nephritis "Shaken baby syndrome symptoms and signs include: Extreme fussiness or irritability Difficulty staying awake Breathing problems Poor eating Vomiting Pale or bluish skin Seizures Paralysis Coma While sometimes there's bruising on the face, you may not see signs of physical injury to the child's outer body. Injuries that might not be immediately seen include bleeding in the brain and eyes, spinal cord damage, and fractures of the ribs, skull, legs and other bones. Many children with shaken baby syndrome show signs and symptoms of prior child abuse. In mild cases of shaken baby syndrome, a child may appear normal after being shaken, but over time they may develop health or behavioral problems.",900,Shaken Baby Syndrome "Movement and coordination: Stiff muscles and exaggerated reflexes (spasticity), the most common movement disorder Variations in muscle tone, such as being either too stiff or too floppy Stiff muscles with normal reflexes (rigidity) Lack of balance and muscle coordination (ataxia) Tremors or jerky involuntary movements Slow, writhing movements Favoring one side of the body, such as only reaching with one hand or dragging a leg while crawling Difficulty walking, such as walking on toes, a crouched gait, a scissors-like gait with knees crossing, a wide gait or an asymmetrical gait Difficulty with fine motor skills, such as buttoning clothes or picking up utensils Speech and eating Delays in speech development Difficulty speaking Difficulty with sucking, chewing or eating Excessive drooling or problems with swallowing Development Delays in reaching motor skills milestones, such as sitting up or crawling Learning difficulties Intellectual disabilities Delayed growth, resulting in smaller size than would be expected Other problems Damage to the brain can contribute to other neurological problems, such as: Seizures (epilepsy) Difficulty hearing Problems with vision and abnormal eye movements Abnormal touch or pain sensations Bladder and bowel problems, including constipation and urinary incontinence Mental health conditions, such as emotional disorders and behavioral problems The brain disorder causing cerebral palsy doesn't change with time, so the symptoms usually don't worsen with age. However, as the child gets older, some symptoms might become more or less apparent. And muscle shortening and muscle rigidity can worsen if not treated aggressively.",183,Cerebral Palsy Symptoms may include: Chest pain. Shortness of breath.,143,Broken Heart Syndrome "A nightmare may involve these features: Your dream seems vivid and real and is very upsetting, often becoming more disturbing as the dream unfolds. Your dream storyline is usually related to threats to safety or survival, but it can have other disturbing themes. Your dream awakens you. You feel scared, anxious, angry, sad or disgusted as a result of your dream. You feel sweaty or have a pounding heartbeat while in bed. You can think clearly upon awakening and can recall details of your dream. Your dream causes distress that keeps you from falling back to sleep easily. Nightmares are only considered a disorder if you experience: Frequent occurrences Major distress or impairment during the day, such as anxiety or persistent fear, or bedtime anxiety about having another nightmare Problems with concentration or memory, or you can't stop thinking about images from your dreams Daytime sleepiness, fatigue or low energy Problems functioning at work or school or in social situations Behavior problems related to bedtime or fear of the dark Having a child with nightmare disorder can cause significant sleep disturbance and distress for parents or caregivers. When to see a doctor Occasional nightmares aren't usually a cause for concern. If your child has nightmares, you can simply mention them at a routine well-child exam. However, consult your doctor if nightmares: Occur frequently and persist over time Routinely disrupt sleep Cause fear of going to sleep Cause daytime behavior problems or difficulty functioning",683,Nightmare Disorder "Aggressive episodes may be preceded or accompanied by: Rage Irritability Increased energy Racing thoughts Tingling Tremors Palpitations Chest tightness The explosive verbal and behavioral outbursts are out of proportion to the situation, with no thought to consequences, and can include: Temper tantrums Tirades Heated arguments Shouting Slapping, shoving or pushing Physical fights Property damage Threatening or assaulting people or animals You may feel a sense of relief and tiredness after the episode. Later, you may feel remorse, regret or embarrassment.",528,Intermittent Explosive Disorder "Back pain can range from a muscle aching to a shooting, burning or stabbing sensation. Also, the pain can radiate down a leg. Bending, twisting, lifting, standing or walking can make it worse.",93,Back Pain A sensation of pelvic pressure A new backache: Mild abdominal cramps A change in vaginal discharge Light vaginal bleeding,516,Incompetent Cervix "Symptoms of de: Quervain tenosynovitis include: Pain near the base of the thumb Swelling near the base of the thumb Difficulty moving the thumb and wrist when doing something that involves grasping or pinching A ""sticking"" or ""stop-and-go"" sensation in the thumb when moving it If the condition goes too long without treatment, the pain may spread farther into the thumb or forearm or both. Moving the thumb and wrist may make the pain worse.",269,De Quervain Tenosynovitis "PVPS: Signs and symptoms of PVPS may include: PVPS Pain and tenderness in the scrotum Pressure or pain after ejaculation Dull ache in one or both testicles Pain and tenderness at the site of the vasectomy Swelling of the small, C-shaped tube behind the testicle where sperm are stored (epididymis) Pain with sex",784,Post Vasectomy Pain Syndrome "you might have signs and symptoms that include: Back pain, caused by a fractured or collapsed vertebra Loss of height over time A stooped posture A bone that breaks much more easily than expected",704,Osteoporosis "Early warning of ectopic pregnancy: Often, the first warning signs of an ectopic pregnancy are light vaginal bleeding and pelvic pain. If blood leaks from the fallopian tube, you may feel shoulder pain or an urge to have a bowel movement. Your specific symptoms depend on where the blood collects and which nerves are irritated. Emergency symptoms If the fertilized egg continues to grow in the fallopian tube, it can cause the tube to rupture. Heavy bleeding inside the abdomen is likely. Symptoms of this life-threatening event include extreme lightheadedness, fainting and shock.",329,Ectopic Pregnancy Signs and symptoms possibly associated with blastocystis include: Watery diarrhea Nausea Abdominal pain Bloating Excessive gas Loss of appetite Weight loss Anal itching Fatigue,116,Blastocystis Hominis Infection "Signs and symptoms may include: Unexplained withdrawal, fear, sadness or irritability Sad and listless appearance Not seeking comfort or showing no response when comfort is given Failure to smile Watching others closely but not engaging in social interaction Failure to reach out when picked up No interest in playing peekaboo or other interactive games Behavior problems Failing to seek support or assistance",839,Reactive Attachment Disorder "Shedding light on dangerous faints: Click here for an infographic to learn more Shedding light on dangerous faints Click here for an infographic to learn more Some people with long QT syndrome (LQTS) do not have any noticeable symptoms. The condition may be discovered when an electrocardiogram (ECG) or genetic testing is done for other reasons. Fainting (syncope) is the most common symptom of long QT syndrome. A fainting spell from long QT syndrome can occur with little to no warning. Some people have fainting warning signs first, including: Blurred vision Lightheadedness Pounding heartbeats (palpitations) Weakness Fainting occurs when the heart temporarily beats in an unorganized way. You might faint when you're excited, angry or scared or during exercise. Things that startle you — for example, a telephone or an alarm clock — can cause you to lose consciousness. Long QT syndrome may also cause seizures in some people. Symptoms of long QT syndrome sometimes occur during sleep. Most people with symptoms of LQTS have their first episode by age 40. When the condition is present at birth (congenital long QT syndrome), symptoms may occur during the first weeks to months of life or later in childhood. LQTS Generally, after a long QT episode, the heart returns to its typical rhythm. If the heart doesn't reset itself or if an external defibrillator isn't used in time to reset the heart rhythm, sudden death will occur.",585,Long Qt Syndrome "Signs and symptoms of granulomatosis with polyangiitis might include: Pus-like drainage with crusts from your nose, stuffiness, sinus infections and nosebleeds Coughing, sometimes with bloody phlegm Shortness of breath or wheezing Fever Fatigue Joint pain Numbness in your limbs, fingers or toes Weight loss Blood in your urine Skin sores, bruising or rashes Eye redness, burning or pain, and vision problems Ear inflammation and hearing problems For some people, the disease affects only the lungs. When the kidneys are affected, blood and urine tests can detect the problem. Without treatment, kidney or lung failure can occur.",427,Granulomatosis With Polyangiitis "Signs and symptoms of testicular torsion include: Sudden, severe pain in the scrotum — the loose bag of skin under your penis that contains the testicles Swelling of the scrotum Abdominal pain Nausea and vomiting A testicle that's positioned higher than normal or at an unusual angle Frequent urination Fever Young boys who have testicular torsion typically wake up due to scrotal pain in the middle of the night or early in the morning.",976,Testicular Torsion "Symptoms of menstrual cramps include: Throbbing or cramping pain in your lower abdomen that can be intense Pain that starts 1 to 3 days before your period, peaks 24 hours after the onset of your period and subsides in 2 to 3 days Dull, continuous ache Pain that radiates to your lower back and thighs Some women also have: Nausea Loose stools Headache Dizziness",617,Menstrual Cramps "Symptoms of somatic symptom disorder may be: Specific sensations, such as pain or shortness of breath, or more general symptoms, such as fatigue or weakness Unrelated to any medical cause that can be identified, or related to a medical condition such as cancer or heart disease, but more significant than what's usually expected A single symptom, multiple symptoms or varying symptoms Mild, moderate or severe Pain is the most common symptom, but whatever your symptoms, you have excessive thoughts, feelings or behaviors related to those symptoms, which cause significant problems, make it difficult to function and sometimes can be disabling. These thoughts, feelings and behaviors can include: Constant worry about potential illness Viewing normal physical sensations as a sign of severe physical illness Fearing that symptoms are serious, even when there is no evidence Thinking that physical sensations are threatening or harmful Feeling that medical evaluation and treatment have not been adequate Fearing that physical activity may cause damage to your body Repeatedly checking your body for abnormalities Frequent health care visits that don't relieve your concerns or that make them worse Being unresponsive to medical treatment or unusually sensitive to medication side effects Having a more severe impairment than is usually expected from a medical condition For somatic symptom disorder, more important than the specific physical symptoms you experience is the way you interpret and react to the symptoms and how they impact your daily life.",923,Somatic Symptom Disorder "Signs and symptoms can include: Tingling or burning in the fingertips, toes and lips Muscle aches or cramps in the legs, feet, stomach or face Twitching or spasms of muscles, particularly around the mouth, but also in the hands, arms and throat Fatigue or weakness Other signs and symptoms associated with hypoparathyroidism can include: Painful menstrual periods Patchy hair loss Dry, coarse skin Brittle nails Depression or anxiety",506,Hypoparathyroidism "A feeling of skin tightness: Skin that feels and looks rough Itchiness (pruritus) Slight to severe flaking skin, which causes the ashy look that can affect dry brown and black skin Slight to severe scaling or peeling Cracked ""dry riverbed"" look to leg Fine lines or cracks Skin that ranges from reddish on white skin to grayish on brown and black skin Deep cracks that may bleed",312,Dry Skin "Baby blues symptoms: Symptoms of baby blues — which last only a few days to a week or two after your baby is born — may include: Mood swings Anxiety Sadness Irritability Feeling overwhelmed Crying Reduced concentration Appetite problems Trouble sleeping Postpartum depression symptoms Postpartum depression may be mistaken for baby blues at first — but the symptoms are more intense and last longer. These may eventually interfere with your ability to care for your baby and handle other daily tasks. Symptoms usually develop within the first few weeks after giving birth. But they may begin earlier — during pregnancy — or later — up to a year after birth. Postpartum depression symptoms may include: Depressed mood or severe mood swings Crying too much Difficulty bonding with your baby Withdrawing from family and friends Loss of appetite or eating much more than usual Inability to sleep, called insomnia, or sleeping too much Overwhelming tiredness or loss of energy Less interest and pleasure in activities you used to enjoy Intense irritability and anger Fear that you're not a good mother Hopelessness Feelings of worthlessness, shame, guilt or inadequacy Reduced ability to think clearly, concentrate or make decisions Restlessness Severe anxiety and panic attacks Thoughts of harming yourself or your baby Recurring thoughts of death or suicide Untreated, postpartum depression may last for many months or longer. Postpartum psychosis With postpartum psychosis — a rare condition that usually develops within the first week after delivery — the symptoms are severe. Symptoms may include: Feeling confused and lost Having obsessive thoughts about your baby Hallucinating and having delusions Having sleep problems Having too much energy and feeling upset Feeling paranoid Making attempts to harm yourself or your baby Postpartum psychosis may lead to life-threatening thoughts or behaviors and requires immediate treatment. Postpartum depression in the other parent Studies show that new fathers can experience postpartum depression, too. They may feel sad, tired, overwhelmed, anxious, or have changes in their usual eating and sleeping patterns. These are the same symptoms that mothers with postpartum depression experience. Fathers who are young, have a history of depression, experience relationship problems or are struggling financially are most at risk of postpartum depression. Postpartum depression in fathers — sometimes called paternal postpartum depression — can have the same negative effect on partner relationships and child development as postpartum depression in mothers can. If you're a partner of a new mother and are having symptoms of depression or anxiety during your partner's pregnancy or after your child's birth, talk to your health care provider. Similar treatments and supports provided to mothers with postpartum depression can help treat postpartum depression in the other parent.",787,Postpartum Depression symptoms may include: Dull pain in the back or side Fever Upper stomach pain,553,Kidney Cysts Erectile dysfunction symptoms might include persistent: Trouble getting an erection Trouble keeping an erection Reduced sexual desire,351,Erectile Dysfunction "Typical signs and symptoms are: Purplish, flat bumps, most often on the inner forearm, wrist or ankle, and sometimes the genitals Itching Blisters that break to form scabs or crusts Lacy white patches in the mouth or on the lips or tongue Painful sores in the mouth or vagina Hair loss Change in scalp color Nail damage or loss",575,Lichen Planus "mouth disease on the hand: Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the palms of the hands. Rashes appear differently depending on skin tone. Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the palms of the hands. Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the palms of the hands. Hand-foot-and-mouth disease on the hand Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the palms of the hands. Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the palms of the hands. Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the soles of the feet. Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the soles of the feet. Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the soles of the feet. Hand-foot-and-mouth disease on the foot Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the soles of the feet. Hand-foot-and-mouth disease often causes a rash of painful, blister-like lesions on the soles of the feet. Hand-foot-and-mouth disease may cause all of the following symptoms or only some of them. They include: Fever. Sore throat. Feeling sick. Painful, blister-like lesions on the tongue, gums and inside of the cheeks. A rash on the palms, soles and sometimes the buttocks. The rash is not itchy, but sometimes it has blisters. Depending on skin tone, the rash may appear red, white, gray, or only show as tiny bumps. Fussiness in infants and toddlers. Loss of appetite. The usual period from initial infection to the time symptoms appear (incubation period) is 3 to 6 days. Children may get a fever and develop a sore throat. They sometimes lose their appetites and don't feel well. One or two days after the fever begins, painful sores may develop in the front of the mouth or throat. A rash on the hands and feet and sometimes on the buttocks may also appear. Sores that develop in the back of the mouth and throat may suggest a related viral illness called herpangina. Other features of herpangina include a sudden high fever and, in some instances, seizure. In rare cases, sores develop on the hands, feet or other parts of the body.",439,Hand Foot And Mouth Disease "might include: Blurred or cloudy vision, sometimes described as a general lack of clarity of vision. Fluctuation in vision, with worse symptoms in the morning after awakening and gradually improving during the day. As the disease progresses, blurred vision either can take longer to improve or doesn't improve. Glare, which can decrease your vision in dim and bright light. Seeing halos around lights. Pain or grittiness from tiny blisters on the surface of your cornea.",392,Fuchs Dystrophy "Inflammation sites: Inflammation sites Inflammation sites Inflammation often affects these sites in people with reactive arthritis. Inflammation sites Inflammation sites Inflammation sites Inflammation sites Inflammation often affects these sites in people with reactive arthritis. Inflammation sites Inflammation sites Inflammation often affects these sites in people with reactive arthritis. Inflammation sites Inflammation often affects these sites in people with reactive arthritis. Inflammation often affects these sites in people with reactive arthritis. The signs and symptoms of reactive arthritis generally start 1 to 4 weeks after exposure to a triggering infection. They might include: Pain and stiffness. The joint pain associated with reactive arthritis most commonly occurs in the knees, ankles and feet. Pain may also occur in the heels, low back or buttocks. Eye inflammation. Many people who have reactive arthritis also develop eye inflammation (conjunctivitis). Urinary problems. Increased frequency and discomfort during urination may occur, as can inflammation of the prostate gland or cervix. Inflammation of tendons and ligaments where they attach to bone (enthesitis). This happens most often in the heels and the sole of the feet. Swollen toes or fingers. In some cases, toes or fingers might become so swollen that they look like sausages. Skin problems. Reactive arthritis can affect skin in a variety of ways, including mouth sores and a rash on the soles of the feet and palms of the hands. Low back pain. The pain tends to be worse at night or in the morning.",838,Reactive Arthritis "you may: Feel a sudden urge to urinate that's difficult to control Experience unintentional loss of urine immediately after an urgent need to urinate (urgency incontinence) Urinate frequently, usually eight or more times in 24 hours Wake up more than two times in the night to urinate (nocturia) Even if you are able to get to the toilet in time when you sense an urge to urinate, unexpected frequent urination and nighttime urination can disrupt your life.",709,Overactive Bladder Retrograde ejaculation signs and symptoms include: Orgasms in which you ejaculate very little or no semen out of your penis (dry orgasms) Urine that is cloudy after orgasm because it contains semen Inability to get a woman pregnant (male infertility),854,Retrograde Ejaculation Later signs and symptoms may include: Fever Headache Nausea Vomiting Agitation Anxiety Confusion Hyperactivity Difficulty swallowing Excessive salivation Fear brought on by attempts to drink fluids because of difficulty swallowing water Fear brought on by air blown on the face Hallucinations Insomnia Partial paralysis,833,Rabies "For example: If you have atherosclerosis in your heart arteries, you may have chest pain or pressure (angina). If you have atherosclerosis in the arteries leading to your brain, you may have sudden numbness or weakness in your arms or legs, difficulty speaking or slurred speech, temporary loss of vision in one eye, or drooping muscles in your face. These signal a transient ischemic attack (TIA). Untreated, a TIA can lead to a stroke. If you have atherosclerosis in the arteries in your arms and legs, you may have symptoms of peripheral artery disease, such as leg pain when walking (claudication) or decreased blood pressure in an affected limb. If you have atherosclerosis in the arteries leading to your kidneys, you may develop high blood pressure or kidney failure.",69,Arteriosclerosis Atherosclerosis "You might experience: Irregular periods. As ovulation becomes more unpredictable, the length of time between periods may be longer or shorter, your flow may be light to heavy, and you may skip some periods. If you have a persistent change of seven days or more in the length of your menstrual cycle, you may be in early perimenopause. If you have a space of 60 days or more between periods, you're likely in late perimenopause. Hot flashes and sleep problems. Hot flashes are common during perimenopause. The intensity, length and frequency vary. Sleep problems are often due to hot flashes or night sweats, but sometimes sleep becomes unpredictable even without them. Mood changes. Mood swings, irritability or increased risk of depression may happen during perimenopause. The cause of these symptoms may be sleep disruption associated with hot flashes. Mood changes may also be caused by factors not related to the hormonal changes of perimenopause. Vaginal and bladder problems. When estrogen levels diminish, your vaginal tissues may lose lubrication and elasticity, making intercourse painful. Low estrogen may also leave you more vulnerable to urinary or vaginal infections. Loss of tissue tone may contribute to urinary incontinence. Decreasing fertility. As ovulation becomes irregular, your ability to conceive decreases. However, as long as you're having periods, pregnancy is still possible. If you wish to avoid pregnancy, use birth control until you've had no periods for 12 months. Changes in sexual function. During perimenopause, sexual arousal and desire may change. But if you had satisfactory sexual intimacy before menopause, this will likely continue through perimenopause and beyond. Loss of bone. With declining estrogen levels, you start to lose bone more quickly than you replace it, increasing your risk of osteoporosis — a disease that causes fragile bones. Changing cholesterol levels. Declining estrogen levels may lead to unfavorable changes in your blood cholesterol levels, including an increase in low-density lipoprotein (LDL) cholesterol — the ""bad"" cholesterol — which contributes to an increased risk of heart disease. At the same time, high-density lipoprotein (HDL) cholesterol — the ""good"" cholesterol — decreases in many women as they age, which also increases the risk of heart disease.",739,Perimenopause "Mild to moderate OHSS: With mild to moderate ovarian hyperstimulation syndrome, symptoms can include: Mild to moderate abdominal pain Abdominal bloating or increased waist size Nausea Vomiting Diarrhea Tenderness in the area of your ovaries Some women who use injectable fertility drugs get a mild form of OHSS. This usually goes away after about a week. But, if pregnancy occurs, symptoms of OHSS may worsen and last several days to weeks. OHSS OHSS Severe OHSS With severe ovarian hyperstimulation syndrome, you might have: Rapid weight gain — more than 2.2 pounds (1 kilogram) in 24 hours Severe abdominal pain Severe, persistent nausea and vomiting Blood clots Decreased urination Shortness of breath Tight or enlarged abdomen",708,Ovarian Hyperstimulation Syndrome Ohss "Signs and symptoms of a ruptured eardrum may include: Ear pain that may subside quickly Mucuslike, pus-filled or bloody drainage from the ear Hearing loss Ringing in the ear (tinnitus) Spinning sensation (vertigo) Nausea or vomiting that can result from vertigo",869,Ruptured Eardrum "The liver: The liver The liver The liver is your largest internal organ. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach. The liver The liver The liver The liver The liver is your largest internal organ. The liver The liver The liver is your largest internal organ. The liver The liver is your largest internal organ. The liver is your largest internal organ. NAFLD usually causes no signs and symptoms. When it does, they may include: NAFLD Fatigue Pain or discomfort in the upper right abdomen Possible signs and symptoms of NASH and advanced scarring (cirrhosis) include: NASH Abdominal swelling (ascites) Enlarged blood vessels just beneath the skin's surface Enlarged spleen Red palms Yellowing of the skin and eyes (jaundice)",685,Nonalcoholic Fatty Liver Disease "you might develop: Spots or dark strings floating in your vision (floaters) Blurred vision Fluctuating vision Dark or empty areas in your vision Vision loss When to see an eye doctor Careful management of your diabetes is the best way to prevent vision loss. If you have diabetes, see your eye doctor for a yearly eye exam with dilation — even if your vision seems fine. Developing diabetes when pregnant (gestational diabetes) or having diabetes before becoming pregnant can increase your risk of diabetic retinopathy. If you're pregnant, your eye doctor might recommend additional eye exams throughout your pregnancy. Contact your eye doctor right away if your vision changes suddenly or becomes blurry, spotty or hazy. More InformationScreening for diabetic macular edema: How often?Spotting symptoms of diabetic macular edema",292,Diabetic Retinopathy "HIV AIDS: Primary infection (Acute HIV) Some people infected by HIV develop a flu-like illness within 2 to 4 weeks after the virus enters the body. This illness, known as primary (acute) HIV infection, may last for a few weeks. HIV HIV Possible signs and symptoms include: Fever Headache Muscle aches and joint pain Rash Sore throat and painful mouth sores Swollen lymph glands, mainly on the neck Diarrhea Weight loss Cough Night sweats These symptoms can be so mild that you might not even notice them. However, the amount of virus in your bloodstream (viral load) is quite high at this time. As a result, the infection spreads more easily during primary infection than during the next stage. Clinical latent infection (Chronic HIV) In this stage of infection, HIV is still present in the body and in white blood cells. However, many people may not have any symptoms or infections during this time. HIV This stage can last for many years if you're receiving antiretroviral therapy (ART). Some people develop more severe disease much sooner. Symptomatic HIV infection As the virus continues to multiply and destroy your immune cells — the cells in your body that help fight off germs — you may develop mild infections or chronic signs and symptoms such as: Fever Fatigue Swollen lymph nodes — often one of the first signs of HIV infection Diarrhea Weight loss Oral yeast infection (thrush) Shingles (herpes zoster) Pneumonia Progression to AIDS Access to better antiviral treatments has dramatically decreased deaths from AIDS worldwide, even in resource-poor countries. Thanks to these life-saving treatments, most people with HIV in the U.S. today don't develop AIDS. Untreated, HIV typically turns into AIDS in about 8 to 10 years. AIDS HIV AIDS HIV AIDS When AIDS occurs, your immune system has been severely damaged. You'll be more likely to develop diseases that wouldn't usually cause illness in a person with a healthy immune system. These are called opportunistic infections or opportunistic cancers. AIDS The signs and symptoms of some of these infections may include: Sweats Chills Recurring fever Chronic diarrhea Swollen lymph glands Persistent white spots or unusual lesions on your tongue or in your mouth Persistent, unexplained fatigue Weakness Weight loss Skin rashes or bumps",483,Hiv Aids "Symptoms of sudden cardiac arrest are immediate and severe and include: Sudden collapse. No pulse. No breathing. Loss of consciousness. Sometimes other symptoms occur before sudden cardiac arrest. These might include: Chest discomfort. Shortness of breath. Weakness. Fast-beating, fluttering or pounding heart called palpitations. But sudden cardiac arrest often occurs with no warning.",952,Sudden Cardiac Arrest "PDA: Poor eating, which leads to poor growth. Sweating with crying or eating. Persistent fast breathing or breathlessness. Easy tiring. Rapid heart rate.",724,Patent Ductus Arteriosus "AVM AVM: Symptoms usually develop when people are in their 20s, although almost 20% of people diagnosed with spinal AVM are under the age of 16. AVM Symptoms may start suddenly or slowly. Symptoms usually include: Problems with walking or climbing stairs Numbness, tingling or sudden pain in the legs Weakness on one or both sides of the body As the condition gets worse, you may have more symptoms including: Sudden, severe back pain Lack of feeling in the legs Difficulty urinating or having bowel movements Headache Stiff neck Sensitivity to light",929,Spinal Arteriovenous Malformation "Hives: The welts associated with hives can be: Skin-colored, reddish on white skin, or purplish on black and brown skin Itchy, ranging from mild to intense Round, oval or worm-shaped As small as a pea or as large as a dinner plate Most hives appear quickly and go away within 24 hours. This is known as acute hives. Chronic hives can last for months or years. Angioedema Angioedema is a reaction similar to hives that affects deeper layers of the skin. It can appear with hives or alone. Signs and symptoms include: Welts that form in minutes to hours Swelling, especially around the eyes, cheeks or lips Mild pain and warmth in the affected areas",484,Hives And Angioedema Laryngitis signs and symptoms can include: Hoarseness Weak voice or voice loss Tickling sensation and rawness in your throat Sore throat Dry throat Dry cough,564,Laryngitis "Acute sinusitis signs and symptoms often include: Thick, yellow or greenish mucus from the nose (runny nose) or down the back of the throat (postnasal drainage) Blocked or stuffy nose (congestion) causing difficulty breathing through your nose Pain, tenderness, swelling and pressure around your eyes, cheeks, nose or forehead that worsens when bending over Other signs and symptoms include: Ear pressure Headache Aching in your teeth Altered sense of smell Cough Bad breath Fatigue Fever",16,Acute Sinusitis Signs and symptoms of astigmatism may include: Blurred or distorted vision Eyestrain or discomfort Headaches Difficulty with night vision Squinting,78,Astigmatism Signs and symptoms of floor of the mouth cancer can include: Mouth pain Sores in your mouth that won't heal Loose teeth Pain when you swallow Weight loss Ear pain Swelling in your neck that may hurt White patches in your mouth that won't go away,382,Floor Mouth Cancer "A broken wrist might cause these signs and symptoms: Severe pain that might worsen when gripping or squeezing or moving your hand or wrist Swelling Tenderness Bruising Obvious deformity, such as a bent wrist When to call a doctor If you think you might have a broken wrist, see a doctor immediately, especially if you have numbness, swelling or trouble moving your fingers. A delay in diagnosis and treatment can lead to poor healing, decreased range of motion and decreased grip strength.",148,Broken Wrist "Ataxia is a sign of several neurological disorders and can cause: Poor coordination Walking unsteadily or with the feet set wide apart Poor balance Difficulty with fine motor tasks, such as eating, writing or buttoning a shirt Change in speech Involuntary back-and-forth eye movements (nystagmus) Difficulty swallowing",79,Ataxia "Typical signs and symptoms include: Sudden severe chest or upper back pain, often described as a tearing or ripping sensation, that spreads to the neck or down the back Sudden severe stomach pain Loss of consciousness Shortness of breath Symptoms similar to those of a stroke, including sudden vision problems, difficulty speaking, and weakness or loss of movement (paralysis) on one side of your body Weak pulse in one arm or thigh compared with the other Leg pain Difficulty walking",62,Aortic Dissection "might include: High blood pressure (hypertension) — 140/90 millimeters of mercury (mm Hg) or greater Excess protein in your urine (proteinuria) Severe headaches Changes in vision, including temporary loss of vision, blurred vision or light sensitivity Pain in your upper belly, usually under the ribs on the right side Nausea and vomiting Shortness of breath Decreased urination",788,Postpartum Preeclampsia "CVID: If you have CVID, you'll likely experience repeated infections before being diagnosed. The most common types of infections include pneumonia, sinusitis, ear infections and gastrointestinal infections.",236,Common Variable Immunodeficiency "Cervicitis: Cervicitis Cervicitis With cervicitis, an inflammation of your cervix, your cervix appears red and irritated and may produce a pus-like discharge. Cervicitis Cervicitis Cervicitis Cervicitis With cervicitis, an inflammation of your cervix, your cervix appears red and irritated and may produce a pus-like discharge. Cervicitis Cervicitis With cervicitis, an inflammation of your cervix, your cervix appears red and irritated and may produce a pus-like discharge. Cervicitis With cervicitis, an inflammation of your cervix, your cervix appears red and irritated and may produce a pus-like discharge. With cervicitis, an inflammation of your cervix, your cervix appears red and irritated and may produce a pus-like discharge. Most often, cervicitis causes no signs and symptoms, and you may only learn you have the condition after a pelvic exam performed by your doctor for another reason. If you do have signs and symptoms, they may include: Large amounts of unusual vaginal discharge Frequent, painful urination Pain during sex Bleeding between menstrual periods Vaginal bleeding after sex, not associated with a menstrual period",187,Cervicitis "When to see a doctor: See your doctor if you've had unexplained shortness of breath for several months, especially if it's getting worse or it's interfering with your daily activities. Don't ignore it by telling yourself it's because you're aging or out of shape. Seek immediate medical attention if: You're so short of breath, you can't climb stairs Your lips or fingernails turn blue or gray with exertion You're not mentally alert",336,Emphysema "Swollen lymph nodes: Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. The inset shows three swollen lymph nodes below the lower jaw. Swollen lymph nodes Swollen lymph nodes Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. Swollen lymph nodes Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. Swollen lymph nodes One of the most common places to find swollen lymph nodes is in the neck. One of the most common places to find swollen lymph nodes is in the neck. Signs and symptoms of non-Hodgkin's lymphoma may include: Swollen lymph nodes in your neck, armpits or groin Abdominal pain or swelling Chest pain, coughing or trouble breathing Persistent fatigue Fever Night sweats Unexplained weight loss",684,Non Hodgkins Lymphoma "Small vessel disease signs and symptoms include: Chest pain, squeezing or discomfort (angina), which may get worse with activity or emotional stress Discomfort in the left arm, jaw, neck, back or abdomen along with chest pain Shortness of breath Tiredness and lack of energy If you've been treated for coronary artery disease with angioplasty and stents and your signs and symptoms haven't gone away, you might also have small vessel disease.",917,Small Vessel Disease "signs and symptoms of chondrosarcoma may include: Increasing pain A growing lump or area of swelling Weakness or bowel and bladder control problems, if the cancer presses on the spinal cord Causes It's not clear what causes chondrosarcoma. Doctors know that cancer begins when a cell develops changes (mutations) in its DNA. A cell's DNA contains the instructions that tell it what to do. The instructions tell the cell to multiply quickly and to continue living when healthy cells would die. The accumulating cells form a tumor that can grow to invade and destroy normal body tissue. In time, cells can break away and spread (metastasize) to other areas of the body. Risk factors Factors that can increase the risk of chondrosarcoma include: Increasing age. Chondrosarcoma occurs most often in middle-aged and older adults, though it can occur at any age. Other bone diseases. Ollier's disease and Maffucci's syndrome are conditions that cause noncancerous bone growths (enchondromas) in the body. These growths sometimes transform into chondrosarcoma. By Mayo Clinic Staff By Mayo Clinic Staff Chondrosarcoma care at Mayo Clinic",206,Chondrosarcoma "Genital herpes: Genital herpes Genital herpes Sores associated with genital herpes can be small bumps, blisters or open sores. Scabs eventually form and the sores heal, but they tend to recur. Genital herpes Genital herpes Genital herpes Genital herpes Sores associated with genital herpes can be small bumps, blisters or open sores. Genital herpes Genital herpes Sores associated with genital herpes can be small bumps, blisters or open sores. Genital herpes Sores associated with genital herpes can be small bumps, blisters or open sores. Sores associated with genital herpes can be small bumps, blisters or open sores. Most people infected with HSV don't know they have it. They may have no symptoms or have very mild symptoms. HSV Symptoms start about 2 to 12 days after exposure to the virus. They may include: Pain or itching around the genitals Small bumps or blisters around the genitals, anus or mouth Painful ulcers that form when blisters rupture and ooze or bleed Scabs that form as the ulcers heal Painful urination Discharge from the urethra, the tube that releases urine from the body Discharge from the vagina During the first outbreak, you may commonly have flu-like symptoms such as: Fever Headache Body aches Swollen lymph nodes in the groin Differences in symptom location Sores appear where the infection enters the body. You can spread the infection by touching a sore and then rubbing or scratching another area of your body. That includes your fingers or eyes. Sore can develop on or in the: Buttocks Thighs Rectum Anus Mouth Urethra Vulva Vagina Cervix Penis Scrotum Repeat outbreaks After the first outbreak of genital herpes, symptoms often appear again. These are called recurrent outbreaks or recurrent episodes. How often recurrent outbreaks happen varies widely. You'll usually have the most outbreaks the first year after infection. They may appear less often over time. Your symptoms during recurrent outbreaks usually don't last as long and aren't as severe as the first. You may have warning signs a few hours or days before a new outbreak starts. These are called prodromal symptoms. They include: Genital pain Tingling or shooting pain in the legs, hips or buttocks",409,Genital Herpes "A red lump on your eyelid that is similar to a boil or a pimple: Eyelid pain Eyelid swelling Tearing Another condition that causes inflammation of the eyelid is a chalazion. A chalazion occurs when there's a blockage in one of the small oil glands near the eyelashes. Unlike a stye, a chalazion usually isn't painful and tends to be most prominent on the inner side of the eyelid. Treatment for both conditions is similar.",950,Sty "signs and symptoms may include: Feeling tired, weak or short of breath, usually because of anemia Pain or fullness below your ribs on the left side, due to an enlarged spleen Easy bruising Easy bleeding Excessive sweating during sleep (night sweats) Fever Bone pain",661,Myelofibrosis diabetes include: Increased thirst Frequent urination Increased hunger Fatigue Blurred vision Numbness or tingling in the feet or hands Frequent infections Slow-healing sores Unintended weight loss,792,Prediabetes "Common signs and symptoms of chronic sinusitis include: Nasal inflammation Thick, discolored discharge from the nose (runny nose) Drainage down the back of the throat (postnasal drainage) Blocked or stuffy (congested) nose causing difficulty breathing through your nose Pain, tenderness and swelling around your eyes, cheeks, nose or forehead Reduced sense of smell and taste Other signs and symptoms can include: Ear pain Headache Aching in your upper jaw and teeth Cough or throat clearing Sore throat Bad breath Fatigue Chronic sinusitis and acute sinusitis have similar signs and symptoms. But acute sinusitis is a temporary infection of the sinuses often associated with a cold. The signs and symptoms of chronic sinusitis last at least 12 weeks, but you may have several episodes of acute sinusitis before developing chronic sinusitis. Fever isn't a common sign of chronic sinusitis, but you might have one with acute sinusitis.",218,Chronic Sinusitis "Signs and symptoms of measles typically include: Fever Dry cough Runny nose Sore throat Inflamed eyes (conjunctivitis) Tiny white spots with bluish-white centers on a red background found inside the mouth on the inner lining of the cheek — also called Koplik's spots A skin rash made up of large, flat blotches that often flow into one another The infection occurs in stages over 2 to 3 weeks. Infection and incubation. For the first 10 to 14 days after infection, the measles virus spreads in the body. There are no signs or symptoms of measles during this time. Nonspecific signs and symptoms. Measles typically begins with a mild to moderate fever, often with a persistent cough, a runny nose, inflamed eyes (conjunctivitis) and a sore throat. This relatively mild illness may last 2 to 3 days. Acute illness and rash. The rash is made up of small red spots, some of which are slightly raised. Spots and bumps in tight clusters give the skin a splotchy red appearance. The face breaks out first. Over the next few days, the rash spreads down the arms, chest and back, then over the thighs, lower legs and feet. At the same time, the fever rises sharply, often as high as 104 to 105.8 F (40 to 41 C). Recovery. The measles rash may last about seven days. The rash gradually fades first from the face and last from the thighs and feet. As other symptoms of the illness go away, the cough and darkening or peeling of the skin where the rash was may stay for about 10 days. When can a person spread the measles virus? A person with measles can spread the virus to others for about eight days, starting four days before the rash appears and ending when the rash has been present for four days.",606,Measles "psoriatic arthritis is more likely to also cause: Swollen fingers and toes. Psoriatic arthritis can cause a painful, sausage-like swelling of your fingers and toes. Foot pain. Psoriatic arthritis can also cause pain at the points where tendons and ligaments attach to your bones — especially at the back of your heel (Achilles tendinitis) or in the sole of your foot (plantar fasciitis). Lower back pain. Some people develop a condition called spondylitis as a result of psoriatic arthritis. Spondylitis mainly causes inflammation of the joints between the vertebrae of your spine and in the joints between your spine and pelvis (sacroiliitis). Nail changes. Nails can form tiny dents (pits), crumble or separate from the nail beds. Eye inflammation. Uveitis can cause eye pain, redness and blurry vision. If untreated, uveitis can lead to vision loss.",823,Psoriatic Arthritis "Signs and symptoms of constipation in children may include: Less than three bowel movements a week Bowel movements that are hard, dry and difficult to pass Pain while having a bowel movement Stomach pain Traces of liquid or pasty stool in your child's underwear — a sign that stool is backed up in the rectum Blood on the surface of hard stool If your child fears that having a bowel movement will hurt, he or she may try to avoid it. You may notice your child crossing his or her legs, clenching his or her buttocks, twisting his or her body, or making faces when attempting to hold stool.",245,Constipation In Children "Severe polyhydramnios may cause: Shortness of breath or the inability to breathe Swelling in the lower extremities and abdominal wall Uterine discomfort or contractions Fetal malposition, such as breech presentation Your health care provider may also suspect polyhydramnios if your uterus is excessively enlarged and he or she has trouble feeling the baby.",773,Polyhydramnios "Early indications of mixed connective tissue disease can include: General feeling of being unwell. This can include increased fatigue and a mild fever. Cold and numb fingers or toes (Raynaud's phenomenon). In response to cold or stress, your fingers or toes might turn white and then purplish blue. After warming, the fingers or toes turn red. Swollen fingers or hands. Some people have swelling of the fingers. Muscle and joint pain. Joints can become inflamed, swollen and deformed, similar to what occurs with rheumatoid arthritis. Rash. Red or reddish brown patches can appear over the knuckles.",640,Mixed Connective Tissue Disease Signs and symptoms of ureteral cancer include: Blood in urine Back pain Pain when urinating Losing weight without trying Fatigue,1032,Ureteral Cancer "Bone spurs on spine: Bone spurs on spine Bone spurs on spine In osteoarthritis of the spine, disks narrow and bone spurs form. Bone spurs on spine Bone spurs on spine Bone spurs on spine Bone spurs on spine In osteoarthritis of the spine, disks narrow and bone spurs form. Bone spurs on spine Bone spurs on spine In osteoarthritis of the spine, disks narrow and bone spurs form. Bone spurs on spine In osteoarthritis of the spine, disks narrow and bone spurs form. In osteoarthritis of the spine, disks narrow and bone spurs form. Osteoarthritis of the hip Osteoarthritis of the hip Osteoarthritis of the hip The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. Osteoarthritis of the hip Osteoarthritis of the hip Osteoarthritis of the hip Osteoarthritis of the hip The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. Osteoarthritis of the hip Osteoarthritis of the hip The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. Osteoarthritis of the hip The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. The hip joint shown on the left side of the image is normal, but the hip joint shown on the right side of the image shows deterioration of cartilage and the formation of bone spurs due to osteoarthritis. Osteoarthritis symptoms often develop slowly and worsen over time. Signs and symptoms of osteoarthritis include: Pain. Affected joints might hurt during or after movement. Stiffness. Joint stiffness might be most noticeable upon awakening or after being inactive. Tenderness. Your joint might feel tender when you apply light pressure to or near it. Loss of flexibility. You might not be able to move your joint through its full range of motion. Grating sensation. You might feel a grating sensation when you use the joint, and you might hear popping or crackling. Bone spurs. These extra bits of bone, which feel like hard lumps, can form around the affected joint. Swelling. This might be caused by soft tissue inflammation around the joint.",701,Osteoarthritis "Some children might experience these signs and symptoms as a result of too much sugar in their bloodstreams: Increased thirst Frequent urination Increased hunger Fatigue Blurry vision Darkened areas of skin, most often around the neck or in the armpits and groin Unintended weight loss, although this is less common in children with type 2 diabetes than in children with type 1 diabetes Frequent infections",1025,Type 2 Diabetes In Children "Signs and symptoms of transposition of the great arteries after birth include: Blue color of the skin (cyanosis) Shortness of breath Weak pulse Lack of appetite Poor weight gain A blue skin color may not be as noticeable in babies who are born with transposition of the great arteries and other congenital heart defects. This is because these other heart conditions — such as atrial septal defect, ventricular septal defect or patent ductus arteriosus — may allow some oxygen-rich blood to travel through the body. But as the baby becomes more active, the congenital heart defects won't allow enough blood through and eventually the blue skin color will become obvious.",1006,Transposition Of The Great Arteries "Symptoms include uncontrolled spasms in your diaphragm and a ""hic"" sound. Sometimes you may feel a slight tightening sensation in your chest, stomach area or throat.",473,Hiccups "Most kids are fully toilet trained by age 5, but there's really no target date for developing complete bladder control. Between the ages of 5 and 7, bed-wetting remains a problem for some children. After 7 years of age, a small number of children still wet the bed.",103,Bed Wetting "Atrial septal defect signs and symptoms can include: Shortness of breath, especially when exercising Fatigue Swelling of legs, feet or belly (abdomen) Irregular heartbeats (arrhythmias) Sensation of a rapid, pounding heartbeat (palpitations) or skipped beats Whooshing sound that can be heard through a stethoscope (heart murmur)",84,Atrial Septal Defect "A cold sore usually passes through several stages: Tingling and itching. Many people feel itching, burning or tingling around the lips for a day or so before a small, hard, painful spot appears and blisters erupt. Blisters. Small fluid-filled blisters typically erupt along the border of your lips. Sometimes they appear around the nose or cheeks or inside the mouth. Oozing and crusting. The small blisters may merge and then burst, leaving shallow open sores that ooze and crust over. Signs and symptoms vary, depending on whether this is your first outbreak or a recurrence. The first time you have a cold sore, symptoms may not start for up to 20 days after you were first exposed to the virus. The sores can last several days, and the blisters can take two to three weeks to heal completely. Recurrences typically appear at the same spot each time and tend to be less severe than the first outbreak. In a first-time outbreak, you also might experience: Fever Painful gums Sore throat Headache Muscle aches Swollen lymph nodes Children under 5 years old may have cold sores inside their mouths and the lesions are commonly mistaken for canker sores. Canker sores involve only the mucous membrane and aren't caused by the herpes simplex virus.",228,Cold Sore "Signs and symptoms of primary immunodeficiency can include: Frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections Inflammation and infection of internal organs Blood disorders, such as low platelet count or anemia Digestive problems, such as cramping, loss of appetite, nausea and diarrhea Delayed growth and development Autoimmune disorders, such as lupus, rheumatoid arthritis or type 1 diabetes",807,Primary Immunodeficiency "Bile reflux signs and symptoms include: Upper abdominal pain that may be severe Frequent heartburn — a burning sensation in your chest that sometimes spreads to your throat, along with a sour taste in your mouth Nausea Vomiting a greenish-yellow fluid (bile) Occasionally, a cough or hoarseness Unintended weight loss",109,Bile Reflux "Enlarged thyroid: Enlarged thyroid Enlarged thyroid Widespread enlargement of the thyroid can expand the gland well beyond its typical size (left) and cause a noticeable bulge in the neck (right). Enlarged thyroid Enlarged thyroid Enlarged thyroid Enlarged thyroid Widespread enlargement of the thyroid can expand the gland well beyond its typical size (left) and cause a noticeable bulge in the neck (right). Enlarged thyroid Enlarged thyroid Widespread enlargement of the thyroid can expand the gland well beyond its typical size (left) and cause a noticeable bulge in the neck (right). Enlarged thyroid Widespread enlargement of the thyroid can expand the gland well beyond its typical size (left) and cause a noticeable bulge in the neck (right). Widespread enlargement of the thyroid can expand the gland well beyond its typical size (left) and cause a noticeable bulge in the neck (right). Common signs and symptoms of Graves' disease include: Anxiety and irritability A fine tremor of the hands or fingers Heat sensitivity and an increase in perspiration or warm, moist skin Weight loss, despite normal eating habits Enlargement of the thyroid gland (goiter) Change in menstrual cycles Erectile dysfunction or reduced libido Frequent bowel movements Bulging eyes (Graves' ophthalmopathy) Fatigue Thick, red skin usually on the shins or tops of the feet (Graves' dermopathy) Rapid or irregular heartbeat (palpitations) Sleep disturbance Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy signs and symptoms include bulging eyes, redness and retracting eyelids. Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy signs and symptoms include bulging eyes, redness and retracting eyelids. Graves' ophthalmopathy Graves' ophthalmopathy Graves' ophthalmopathy signs and symptoms include bulging eyes, redness and retracting eyelids. Graves' ophthalmopathy Graves' ophthalmopathy signs and symptoms include bulging eyes, redness and retracting eyelids. Graves' ophthalmopathy signs and symptoms include bulging eyes, redness and retracting eyelids. About 30% of people with Graves' disease show some signs and symptoms of Graves' ophthalmopathy. In Graves' ophthalmopathy, inflammation and other immune system events affect muscles and other tissues around your eyes. Signs and symptoms may include: Bulging eyes Gritty sensation in the eyes Pressure or pain in the eyes Puffy or retracted eyelids Reddened or inflamed eyes Light sensitivity Double vision Vision loss Graves' dermopathy Graves' dermopathy Graves' dermopathy Graves' dermopathy Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). This results from a buildup of protein in the skin. It often occurs on the shins and on the tops of the feet. Graves' dermopathy Graves' dermopathy Graves' dermopathy Graves' dermopathy Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). Graves' dermopathy Graves' dermopathy Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). Graves' dermopathy Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). Rarely, people who have Graves' disease develop a reddish thickening of the skin that resembles the texture of an orange peel (Graves' dermopathy). An uncommon manifestation of Graves' disease, called Graves' dermopathy, is the reddening and thickening of the skin, most often on your shins or the tops of your feet.",428,Graves Disease "and may include: Skin lesions. Most people with cryoglobulinemia develop purplish skin lesions on their legs. In some people, leg ulcers also occur. Joint pain. Symptoms resembling rheumatoid arthritis are common in cryoglobulinemia. Peripheral neuropathy. Cryoglobulinemia can damage the nerves at the tips of your fingers and toes, causing numbness and other problems. Causes Cryoglobulinemia has been associated with: Infections. Hepatitis C is the most common infection associated with cryoglobulinemia. Others include hepatitis B, HIV, Epstein-Barr, toxoplasmosis and malaria. Certain cancers. Some cancers of the blood, such as multiple myeloma, Waldenstrom macroglobulinemia and chronic lymphocytic leukemia, can sometimes cause cryoglobulinemia. Autoimmune disorders. Disease such as lupus, rheumatoid arthritis and Sjogren's syndrome increase the risk of developing cryoglobulinemia. Risk factors Risk factors of cryoglobulinemia may include: Your sex. Cryoglobulinemia occurs more frequently in women than in men. Age. Symptoms of cryoglobulinemia usually begin in middle age. Other diseases. Cryoglobulinemia is associated with diseases such as hepatitis C, HIV, multiple myeloma, Waldenstrom macroglobulinemia, lupus and Sjogren's syndrome. By Mayo Clinic Staff By Mayo Clinic Staff Cryoglobulinemia care at Mayo Clinic",258,Cryoglobulinemia "See a doctor if: You suddenly begin to sweat much more or less than usual Sweating disrupts your daily routine You experience night sweats for no apparent reason You notice a change in your body odor Causes Sweating and body odor are caused by sweat glands in your body. The two main types of sweat glands are eccrine glands and apocrine glands. Eccrine glands occur over most of your body and open directly onto the surface of the skin. When your body temperature rises, these glands release fluids that cool your body as they evaporate. Apocrine glands are found in areas where you have hair, such as your armpits and groin. These glands release a milky fluid when you're stressed. This fluid is odorless until it combines with bacteria on your skin. By Mayo Clinic Staff By Mayo Clinic Staff Request an appointment Request an appointment Diagnosis & treatment Diagnosis & treatment Diagnosis & treatment Oct. 27, 2021 Print Print Share on: FacebookTwitter Facebook Twitter Show references Goldsmith LA, et al., eds. Biology of eccrine and apocrine glands. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed July 6, 2016. Perspiration. Natural Medicines. https://naturalmedicines.therapeuticresearch.com/. Accessed July 7, 2016. Kanlayavattanakul M, et al. Body malodours and their topical treatment agents. International Journal of Cosmetic Science. 2011;33:298. Shirasu M, et al. The scent of disease: Volatile organic compounds of the human body related to disease and disorder. Journal of Biochemistry. 2011;150:257. Hyperhidrosis. American Osteopathic College of Dermatology. http://aocd.site-ym.com/?page=Hyperhidrosis. Smith CC, et al. Primary focal hyperhidrosis. http://www.uptodate.com/home. Show references Goldsmith LA, et al., eds. Goldsmith LA, et al., eds. Related Sweat test Associated Procedures Urinalysis Products & Services Book: Mayo Clinic Book of Home Remedies Related Sweat test Sweat test",958,Sweating And Body Odor "Mild symptoms: Mild latex allergy symptoms include: Itching Skin redness Hives or rash More-severe symptoms These include: Sneezing Runny nose Itchy, watery eyes Scratchy throat Difficulty breathing Wheezing Cough Life-threatening symptoms: Anaphylaxis The most serious allergic reaction to latex is anaphylaxis, which can be deadly. An anaphylactic (an-uh-fuh-LAK-tik) reaction develops immediately after latex exposure in highly sensitive people. However, it rarely happens the first time you're exposed. Symptoms of anaphylaxis include: Difficulty breathing Hives or swelling Nausea and vomiting Wheezing Drop in blood pressure Dizziness Loss of consciousness Confusion Rapid or weak pulse",565,Latex Allergy "Signs and symptoms of cataracts include: Clouded, blurred or dim vision Increasing difficulty with vision at night Sensitivity to light and glare Need for brighter light for reading and other activities Seeing ""halos"" around lights Frequent changes in eyeglass or contact lens prescription Fading or yellowing of colors Double vision in a single eye At first, the cloudiness in your vision caused by a cataract may affect only a small part of the eye's lens and you may be unaware of any vision loss. As the cataract grows larger, it clouds more of your lens and distorts the light passing through the lens. This may lead to more-noticeable symptoms.",176,Cataracts "Symptoms of hoarding disorder may include: Getting and keeping too many items that you may not have a need for right now and don't have space for. Ongoing difficulty throwing out or parting with your things, regardless of their actual value. Feeling a need to save these items and being upset by the thought of getting rid of them. Building up clutter to the point where you can't use rooms. Trying to be perfect and avoiding or delaying decisions. Problems with planning and organizing. Getting too many items and refusing to part with them results in: Disorganized piles or stacks of items, such as newspapers, clothes, paperwork, books or sentimental items. Items that crowd and clutter your walking spaces and living areas. Rooms can't be used for the intended purpose, such as not being able to sleep in your bed. Buildup of food or trash to large, unsanitary levels. Distress or problems functioning or keeping yourself, others and pets safe in your home. Conflict with others who try to reduce or remove clutter from your home. Relationship issues, avoiding social activities and employment problems. Difficulty organizing items and sometimes losing important items in the clutter. With hoarding disorder, items are usually saved because: You believe these items are unique or that you'll need them at some point in the future. You feel emotionally connected to items that remind you of happier times or represent beloved people or pets. You feel safe and comforted when surrounded by things. You don't want to waste anything. Hoarding disorder is different from collecting. People who have collections, such as stamps or model cars, carefully search out specific items, organize them and display their collections. Collections can be large, but they aren't usually cluttered. Also, they don't cause the distress and problems functioning that are part of hoarding disorder. Hoarding animals People who hoard animals may collect dozens or even hundreds of pets. Animals may be confined inside or outside. Because of the large numbers, these animals often aren't cared for properly. The health and safety of the person and the animals are often at risk because of unsanitary conditions.",485,Hoarding Disorder "They include: Reddish or purplish oval patches of skin, often on the belly, chest or back Patches that gradually develop a lighter or whitish center Linear patches, especially on the arms or legs and possibly the forehead or scalp A gradual change in the affected skin, which becomes firm, thickened, dry and shiny Morphea affects the skin and underlying tissue and sometimes bone. The condition generally lasts several years and then improves or at times disappears by itself. It may leave scars or areas of darkened or discolored skin. It is possible for morphea to recur.",647,Morphea "Signs and symptoms of dry socket may include: Severe pain within a few days after a tooth extraction Partial or total loss of the blood clot at the tooth extraction site, which you may notice as an empty-looking (dry) socket Visible bone in the socket Pain that radiates from the socket to your ear, eye, temple or neck on the same side of your face as the extraction Bad breath or a foul odor coming from your mouth Unpleasant taste in your mouth When to see a doctor A certain degree of pain and discomfort is normal after a tooth extraction. However, you should be able to manage normal pain with the pain reliever prescribed by your dentist or oral surgeon, and the pain should lessen with time. If you develop new or worsening pain in the days after your tooth extraction, contact your dentist or oral surgeon immediately.",313,Dry Socket "shaped breast lump: Skin redness or dimpling like an orange Changes in breast size or shape Fluid leaking from your nipple Causes Breast lumps can result from: Breast cysts. If you find a breast lump that feels round, smooth and firm, it could be a cyst — a dilated milk duct filled with fluid. A breast cyst can be large or small, and the surrounding breast tissue may be tender. A breast cyst may appear before your menstrual period and get smaller or disappear afterward. Fibrocystic breast changes. With fibrocystic breast changes, you may feel fullness in your breasts with areas of lumpiness or ridgelike areas. Your breasts may feel tender. Many women experience fibrocystic breast changes related to their menstrual cycles that tend to improve after the menstrual cycle. Fibroadenomas. Fibroadenomas are solid, noncancerous breast tumors that are smooth and move easily under your skin when touched. A fibroadenoma may grow larger. Factors that may be associated with fibroadenoma growth include being pregnant, using hormone therapy or menstruation. Injuries and infections. A severe injury to your breast tissue or nearby nerves can create a breast lump. Doctors describe this condition as fat necrosis. A collection of infected fluid (abscess) in breast tissue also can cause a breast lump, one that's often associated with localized breast pain and inflammation of the skin. Breast cancer. A breast lump that's painless, hard, irregularly shaped and different from surrounding breast tissue might be breast cancer. Skin covering the lump may look red, dimpled or pitted like the skin of an orange. Your breast size and shape may change, or you may notice discharge from the nipple. Only by seeing your doctor for evaluation can you be certain of what kinds of tests you might need and which type of breast lump you have. Clinical trials Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. Explore Mayo Clinic studies By Mayo Clinic Staff By Mayo Clinic Staff Suspicious breast lumps care at Mayo Clinic",957,Suspicious Breast Lumps "Signs and symptoms of: DiGeorge syndrome (22q11.2 deletion syndrome) can vary in type and severity, depending on what body systems are affected and how severe the defects are. Some signs and symptoms may be apparent at birth, but others may not appear until later in infancy or early childhood. Signs and symptoms may include some combination of the following: Heart murmur and bluish skin due to poor circulation of oxygen-rich blood (cyanosis) as a result of a heart defect Frequent infections Certain facial features, such as an underdeveloped chin, low-set ears, wide-set eyes or a narrow groove in the upper lip A gap in the roof of the mouth (cleft palate) or other problems with the palate Delayed growth Difficulty feeding, failure to gain weight or gastrointestinal problems Breathing problems Poor muscle tone Delayed development, such as delays in rolling over, sitting up or other infant milestones Delayed speech development or nasal-sounding speech Learning delays or disabilities Behavior problems When to see a doctor Other conditions may cause signs and symptoms similar to 22q11.2 deletion syndrome. So it's important to get an accurate and prompt diagnosis if your child shows any signs or symptoms listed above. Doctors may suspect 22q11.2 deletion syndrome: At birth. If certain conditions — a severe heart defect, cleft palate or a combination of other factors typical of 22q11.2 deletion syndrome — are readily apparent at birth, diagnostic tests will likely begin before your child leaves the hospital. At well-baby visits. Your family doctor or pediatrician may suspect the disorder because of a combination of illnesses or disorders that become apparent over time. Other issues may come to the attention of your doctor during regularly scheduled well-baby visits or annual checkups for your child.",295,Digeorge Syndrome having any of these signs may mean the condition is secondary hypertension: High blood pressure that doesn't respond to blood pressure medications (resistant hypertension) Very high blood pressure — systolic blood pressure over 180 millimeters of mercury (mm Hg) or diastolic blood pressure over 120 mm Hg High blood pressure that no longer responds to medication that previously controlled the blood pressure Sudden-onset high blood pressure before age 30 or after age 55 No family history of high blood pressure No obesity,893,Secondary Hypertension "They may include: Pain, especially when you bear weight on the affected foot Tenderness when you touch the ankle Swelling Bruising Restricted range of motion Instability in the ankle Popping sensation or sound at the time of injury",935,Sprained Ankle s more advanced may cause signs and symptoms such as: Trouble urinating Decreased force in the stream of urine Blood in the urine Blood in the semen Bone pain Losing weight without trying Erectile dysfunction,815,Prostate Cancer "Signs that you may be addicted include: You can't stop smoking. You've made one or more serious, but unsuccessful, attempts to stop. You have withdrawal symptoms when you try to stop. Your attempts at stopping have caused physical and mood-related symptoms, such as strong cravings, anxiety, irritability, restlessness, difficulty concentrating, depressed mood, frustration, anger, increased hunger, insomnia, constipation or diarrhea. You keep smoking despite health problems. Even though you've developed health problems with your lungs or your heart, you haven't been able to stop. You give up social activities. You may stop going to smoke-free restaurants or stop socializing with family or friends because you can't smoke in these situations.",681,Nicotine Dependence "Some signs and symptoms of nephrogenic systemic fibrosis may include: Swelling and tightening of the skin Reddened or darkened patches on the skin Thickening and hardening of the skin, typically on the arms and legs and sometimes on the body, but almost never on the face or head Skin that may feel ""woody"" and develop an orange-peel appearance Burning, itching or severe sharp pains in areas of involvement Skin thickening that inhibits movement, resulting in loss of joint flexibility Rarely, blisters or ulcers In some people, involvement of muscles and body organs may cause: Muscle weakness Limitation of joint motion caused by muscle tightening (contractures) in arms, hands, legs and feet Bone pain, particularly in the hip bones or ribs Reduced internal organ function, including heart, lung, diaphragm, gastrointestinal tract or liver Yellow plaques on the white surface (sclera) of the eyes The condition is generally long term (chronic), but some people may improve. In a few people, it can cause severe disability, even death.",674,Nephrogenic Systemic Fibrosis "polio syndrome include: Muscle and joint weakness and pain that gets worse over time Feeling easily fatigued and exhausted Losing muscle tissue (atrophy) Breathing or swallowing problems Sleep-related breathing disorders, such as sleep apnea Decreased tolerance of cold temperatures Post-polio syndrome progresses slowly in most people. They may experience new signs and symptoms followed by periods of stability.",782,Post Polio Syndrome "An umbilical hernia creates a soft swelling or bulge near the navel. In babies who have an umbilical hernia, the bulge may be visible only when they cry, cough or strain. Umbilical hernias in children are usually painless. Umbilical hernias that appear during adulthood may cause abdominal discomfort.",1029,Umbilical Hernia "Most people with adult: Still's disease have a combination of the following signs and symptoms: Fever. You might have a daily fever of at least 102 F (38.9 C) for a week or longer. The fever usually peaks in the late afternoon or early evening. You might have two fever spikes daily, with your temperature returning to normal in between. Rash. A salmon-pink rash might come and go with the fever. The rash usually appears on your trunk, arms or legs. Sore throat. This is one of the first symptoms of adult Still's disease. The lymph nodes in your neck might be swollen and tender. Achy and swollen joints. Your joints — especially your knees and wrists — might be stiff, painful and inflamed. Ankles, elbows, hands and shoulders might also ache. The joint discomfort usually lasts at least two weeks. Muscle pain. Muscular pain usually ebbs and flows with the fever, but the pain can be severe enough to disrupt your daily activities. The signs and symptoms of this disorder can mimic those of other conditions, including lupus and a type of cancer called lymphoma.",24,Adult Stills Disease "The most frequent sign of: Gilbert syndrome is an occasional yellowish tinge of the skin and the whites of the eyes as a result of slightly higher levels of bilirubin in the blood. In people with Gilbert syndrome, bilirubin levels may increase due to: Illness, such as a cold or the flu Fasting or eating a very low-calorie diet Dehydration Menstruation Strenuous exercise Stress",416,Gilberts Syndrome "The most common food allergy signs and symptoms include: Tingling or itching in the mouth Hives, itching or eczema Swelling of the lips, face, tongue and throat or other parts of the body Wheezing, nasal congestion or trouble breathing Abdominal pain, diarrhea, nausea or vomiting Dizziness, lightheadedness or fainting Anaphylaxis In some people, a food allergy can trigger a severe allergic reaction called anaphylaxis. This can cause life-threatening signs and symptoms, including: Constriction and tightening of the airways A swollen throat or the sensation of a lump in your throat that makes it difficult to breathe Shock with a severe drop in blood pressure Rapid pulse Dizziness, lightheadedness or loss of consciousness Emergency treatment is critical for anaphylaxis. Untreated, anaphylaxis can cause a coma or even death.",385,Food Allergy "Those who do have atrial fibrillation symptoms may have signs and symptoms such as: Sensations of a fast, fluttering or pounding heartbeat (palpitations) Chest pain Dizziness Fatigue Lightheadedness Reduced ability to exercise Shortness of breath Weakness Atrial fibrillation may be: Occasional (paroxysmal atrial fibrillation). A-fib symptoms come and go, usually lasting for a few minutes to hours. Sometimes symptoms occur for as long as a week and episodes can happen repeatedly. Symptoms might go away on their own. Some people with occasional A-fib need treatment. Persistent. With this type of atrial fibrillation, the heart rhythm doesn't go back to normal on its own. If a person has A-fib symptoms, cardioversion or treatment with medications may be used to restore and maintain a normal heart rhythm. Long-standing persistent. This type of atrial fibrillation is continuous and lasts longer than 12 months. Permanent. In this type of atrial fibrillation, the irregular heart rhythm can't be restored. Medications are needed to control the heart rate and to prevent blood clots.",83,Atrial Fibrillation "A bulging bump on the outside of the base of your big toe: Swelling, redness or soreness around your big toe joint Corns or calluses — these often develop where the first and second toes rub against each other Ongoing pain or pain that comes and goes Limited movement of your big toe",159,Bunions "But larger hiatal hernias can cause: Heartburn Regurgitation of food or liquids into the mouth Backflow of stomach acid into the esophagus (acid reflux) Difficulty swallowing Chest or abdominal pain Feeling full soon after you eat Shortness of breath Vomiting of blood or passing of black stools, which may indicate gastrointestinal bleeding",472,Hiatal Hernia "Examples include: Kidneys. Excess calcium makes your kidneys work harder to filter it. This can cause excessive thirst and frequent urination. Digestive system. Hypercalcemia can cause stomach upset, nausea, vomiting and constipation. Bones and muscles. In most cases, the excess calcium in your blood was leached from your bones, which weakens them. This can cause bone pain and muscle weakness. Brain. Hypercalcemia can interfere with how your brain works, resulting in confusion, lethargy and fatigue. It can also cause depression. Heart. Rarely, severe hypercalcemia can interfere with your heart function, causing palpitations and fainting, indications of cardiac arrhythmia, and other heart problems.",494,Hypercalcemia "Body lice bites can cause intense itching, and you may notice small areas of blood and crust on your skin at the site of the bite marks. See your doctor if improved hygiene doesn't remove the infestation, or if you develop a skin infection from scratching the bites.",121,Body Lice "Signs and symptoms of aortic valve disease may include: Whooshing or swishing heart sound (heart murmur) Chest pain or tightness Dizziness Fainting Fatigue after activity or having less ability to be active Irregular heartbeat Shortness of breath, particularly during vigorous activity or when lying down Not eating enough (mainly in children with aortic valve stenosis) Not gaining enough weight (mainly in children with aortic valve stenosis)",64,Aortic Valve Disease "Causes: Familial adenomatous polyposis is caused by a defect in a gene that's usually inherited from a parent. But some people develop the abnormal gene that causes the condition. Risk factors Your risk of familial adenomatous polyposis is higher if you have a parent, child, brother, or sister with the condition. Complications In addition to colon cancer, familial adenomatous polyposis can cause other complications: Duodenal polyps. These polyps grow in the upper part of your small intestine and may become cancerous. But with careful monitoring, duodenal polyps can often be detected and removed before cancer develops. Periampullary polyps. These polyps occur where the bile and pancreas ducts enter the duodenum (ampulla). Periampullary polyps might become cancerous but can often be detected and removed before cancer develops. Gastric fundic polyps. These polyps grow in the lining of your stomach. Desmoids. These noncancerous masses can arise anywhere in the body but often develop in the stomach area (abdomen). Desmoids can cause serious problems if they grow into nerves or blood vessels or exert pressure on other organs in your body. Other cancers. Rarely, FAP can cause cancer to develop in your thyroid gland, central nervous system, adrenal glands, liver or other organs. Noncancerous (benign) skin tumors. Benign bone growths (osteomas). Congenital hypertrophy of the retinal pigment epithelium (CHRPE). These are benign pigment changes in the retina of your eye. Dental abnormalities. These include extra teeth or teeth that don't come in. Low numbers of red blood cells (anemia). Prevention Preventing FAP is not possible, since it is an inherited genetic condition. However, if you or your child is at risk of FAP because of a family member with the condition, you will need genetic testing and counseling. If you have FAP, you will need regular screening, followed by surgery if needed. Surgery can help prevent the development of colorectal cancer or other complications. By Mayo Clinic Staff By Mayo Clinic Staff Familial adenomatous polyposis care at Mayo Clinic",366,Familial Adenomatous Polyposis "Polymorphous light eruption on the chest: Polymorphous light eruption on the chest Polymorphous light eruption on the chest Polymorphous light eruption is a rash that affects parts of the body that are exposed to more sunlight as daylight hours get longer, such as the front of the neck and chest. Polymorphous means that the rash can have many forms, such as tiny bumps, raised areas or blisters. Polymorphous light eruption on the chest Polymorphous light eruption on the chest Polymorphous light eruption on the chest Polymorphous light eruption on the chest Polymorphous light eruption is a rash that affects parts of the body that are exposed to more sunlight as daylight hours get longer, such as the front of the neck and chest. Polymorphous light eruption on the chest Polymorphous light eruption on the chest Polymorphous light eruption is a rash that affects parts of the body that are exposed to more sunlight as daylight hours get longer, such as the front of the neck and chest. Polymorphous light eruption on the chest Polymorphous light eruption is a rash that affects parts of the body that are exposed to more sunlight as daylight hours get longer, such as the front of the neck and chest. Polymorphous light eruption is a rash that affects parts of the body that are exposed to more sunlight as daylight hours get longer, such as the front of the neck and chest. How skin with sun allergy looks varies widely depending on the color of your skin and what's causing the symptoms. Signs and symptoms may include: Itchiness (pruritus) Stinging Tiny bumps that may merge into raised patches A flushing of the exposed area Blisters or hives Symptoms usually occur only on skin that has been exposed to the sun or other source of UV light. Symptoms show up within minutes to hours after sun exposure.",954,Sun Allergy "Shoulder dislocation: Shoulder dislocation Shoulder dislocation The shoulder joint is the most frequently dislocated joint of the body. Because it moves in several directions, your shoulder can dislocate forward, backward or downward. The most common variety is a forward (anterior) dislocation. Shoulder dislocation Shoulder dislocation Shoulder dislocation Shoulder dislocation The shoulder joint is the most frequently dislocated joint of the body. Shoulder dislocation Shoulder dislocation The shoulder joint is the most frequently dislocated joint of the body. Shoulder dislocation The shoulder joint is the most frequently dislocated joint of the body. The shoulder joint is the most frequently dislocated joint of the body. Dislocated shoulder symptoms can include: A visibly deformed or out-of-place shoulder Swelling or bruising Intense pain Inability to move the joint Shoulder dislocation can also cause numbness, weakness or tingling near the injury, such as in the neck or down the arm. The muscles in the shoulder might spasm, which can increase the pain.",299,Dislocated Shoulder "Symptoms of tricuspid atresia may include: Blue or gray skin and lips due to low blood oxygen levels Difficulty breathing Tiring easily, especially during feedings Slow growth and poor weight gain Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: Fatigue and weakness Shortness of breath Swelling in the legs, ankles and feet Swelling of the belly area, a condition called ascites Sudden weight gain from a buildup of fluid",1013,Tricuspid Atresia "Symptoms of chilblains include: Small, itchy areas on your skin, often on your feet or hands. Sores or blistering. Swelling. Pain or stinging. Changes in skin color.",195,Chilblains "signs and symptoms may include: Shortness of breath with exercise or when you lie down Fatigue and weakness, especially when you increase your activity level Heart murmur Irregular pulse (arrhythmia) Lightheadedness or fainting Chest pain (angina), discomfort or tightness, often increasing during exercise Sensations of a rapid, fluttering heartbeat (palpitations) Swollen ankles and feet",65,Aortic Valve Regurgitation "Toxic epidermal necrolysis signs and symptoms include: Widespread skin pain A spreading rash covering more than 30% of the body Blisters and large areas of peeling skin Sores, swelling and crusting on the mucous membranes, including the mouth, eyes and vagina",999,Toxic Epidermal Necrolysis "Symptoms of jellyfish stings include: Burning, prickling, stinging pain Welts or tracks on the skin — a ""print"" of the tentacles' contact with the skin Itchiness (pruritus) Swelling Throbbing pain that radiates up a leg or an arm Severe jellyfish stings can affect multiple body systems. These reactions may appear rapidly or several hours after the stings. Symptoms of severe jellyfish stings include: Stomach pain, nausea and vomiting Headache Muscle pain or spasms Faintness, dizziness or confusion Difficulty breathing Heart problems The severity of a reaction depends on: The type and size of the jellyfish The age, size and health of the person affected, with severe reactions more likely in children How long the person was exposed to the stingers How much of the skin is affected",543,Jellyfish Stings "Cold urticaria signs and symptoms may include: Temporary itchy welts (hives) on the area of skin that was exposed to cold A worsening of the reaction as the skin warms Swelling of hands while holding cold objects Swelling of lips from consuming cold food or drink Severe reactions may include: A whole-body response (anaphylaxis), which can cause fainting, a racing heart, swelling of limbs or torso, and shock Swelling of the tongue and throat, which can make it difficult to breathe Cold urticaria symptoms begin soon after the skin is exposed to a sudden drop in air temperature or to cold water. Damp and windy conditions may make a flare of symptoms more likely. Each episode may persist for about two hours. The worst reactions generally occur with full skin exposure, such as swimming in cold water. Such a reaction could lead to loss of consciousness and drowning.",229,Cold Urticaria "and any of the following signs and symptoms: Headache Muscle, bone or joint pain Nausea Vomiting Pain behind the eyes Swollen glands Rash Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death. Warning signs of severe dengue fever — which is a life-threatening emergency — can develop quickly. The warning signs usually begin the first day or two after your fever goes away, and may include: Severe stomach pain Persistent vomiting Bleeding from your gums or nose Blood in your urine, stools or vomit Bleeding under the skin, which might look like bruising Difficult or rapid breathing Fatigue Irritability or restlessness",276,Dengue Fever "CDH: Severe trouble breathing due to small lungs that don't work well (pulmonary hypoplasia). A type of high blood pressure that affects the arteries in the lungs and the right side of the heart (pulmonary hypertension). Problems with development of the heart. Damage to the intestines, stomach, liver and other abdominal organs if they move through the hernia into the chest.",241,Congenital Diaphragmatic Hernia Signs and symptoms of a broken toe include: Pain Swelling Change in skin color from bruising or bleeding under the skin,147,Broken Toe "To receive a diagnosis of: Kawasaki disease, a child usually will have a fever greater than 102.2 F (39 C) for five or more days and at least four of the following signs and symptoms. A rash on the main part of the body or in the genital area An enlarged lymph node in the neck Extremely red eyes without a thick discharge Red, dry, cracked lips and an extremely red, swollen tongue Swollen, red skin on the palms of the hands and the soles of the feet, with later peeling of skin on fingers and toes The symptoms might not occur at the same time, so it's important to let your child's health care provider know about a sign or symptom that has gone away. Other signs and symptoms that might develop include: Abdominal pain Diarrhea Irritability Joint pain Vomiting Children with a high fever for five or more days who have fewer than four of the above signs and symptoms might have what's known as incomplete Kawasaki disease. Children with incomplete Kawasaki disease are still at risk of coronary artery injury and still require treatment within 10 days of the onset of symptoms. Kawasaki disease can have symptoms similar to that of multisystem inflammatory syndrome in children, which has occurred worldwide in children with COVID-19. Children with these symptoms will likely be checked for COVID-19, as well.",547,Kawasaki Disease "Your symptoms often depend on which nerve fibers are damaged: Motor nerves. These nerves regulate all the muscles under your conscious control, such as those used for walking, talking and holding objects. Damage to these nerves is typically associated with muscle weakness, painful cramps and uncontrollable muscle twitching. Sensory nerves. Because these nerves relay information about touch, temperature and pain, you may experience a variety of symptoms. These include numbness or tingling in the hands or feet. You may have trouble sensing pain or changes in temperature, walking, keeping your balance with your eyes closed, or fastening buttons. Autonomic (aw-tuh-NOM-ik) nerves. This group of nerves regulates activities that are not controlled consciously, such as breathing, heart and thyroid function, and digesting food. Symptoms may include excessive sweating, changes in blood pressure, the inability to tolerate heat and gastrointestinal symptoms. You may experience a range of symptoms because many peripheral nerve injuries affect more than one type of nerve fiber.",742,Peripheral Nerve Injuries "including any of these signs: Fails to respond to his or her name or appears not to hear you at times Resists cuddling and holding, and seems to prefer playing alone, retreating into his or her own world Has poor eye contact and lacks facial expression Doesn't speak or has delayed speech, or loses previous ability to say words or sentences Can't start a conversation or keep one going, or only starts one to make requests or label items Speaks with an abnormal tone or rhythm and may use a singsong voice or robot-like speech Repeats words or phrases verbatim, but doesn't understand how to use them Doesn't appear to understand simple questions or directions Doesn't express emotions or feelings and appears unaware of others' feelings Doesn't point at or bring objects to share interest Inappropriately approaches a social interaction by being passive, aggressive or disruptive Has difficulty recognizing nonverbal cues, such as interpreting other people's facial expressions, body postures or tone of voice Patterns of behavior A child or adult with autism spectrum disorder may have limited, repetitive patterns of behavior, interests or activities, including any of these signs: Performs repetitive movements, such as rocking, spinning or hand flapping Performs activities that could cause self-harm, such as biting or head-banging Develops specific routines or rituals and becomes disturbed at the slightest change Has problems with coordination or has odd movement patterns, such as clumsiness or walking on toes, and has odd, stiff or exaggerated body language Is fascinated by details of an object, such as the spinning wheels of a toy car, but doesn't understand the overall purpose or function of the object Is unusually sensitive to light, sound or touch, yet may be indifferent to pain or temperature Doesn't engage in imitative or make-believe play Fixates on an object or activity with abnormal intensity or focus Has specific food preferences, such as eating only a few foods, or refusing foods with a certain texture As they mature, some children with autism spectrum disorder become more engaged with others and show fewer disturbances in behavior. Some, usually those with the least severe problems, eventually may lead normal or near-normal lives. Others, however, continue to have difficulty with language or social skills, and the teen years can bring worse behavioral and emotional problems.",87,Autism Spectrum Disorder "Common signs and symptoms include: Diarrhea Nausea, and sometimes, vomiting Stomach cramps Bloating Gas",563,Lactose Intolerance A burning pain in the chest that usually occurs after eating and may occur at night: Pain that worsens when lying down or bending over A bitter or acidic taste in the mouth,453,Heartburn "Gallbladder cancer signs and symptoms may include: Abdominal pain, particularly in the upper right portion of the abdomen Abdominal bloating Losing weight without trying Yellowing of the skin and whites of the eyes (jaundice)",396,Gallbladder Cancer "Symptoms may include: Extreme fatigue Weight loss and loss of appetite Areas of darkened skin Low blood pressure, even fainting Salt craving Low blood sugar, also called hypoglycemia Nausea, diarrhea or vomiting Abdominal pain Muscle and joint pain Irritability Depression Body hair loss or sexual issues in some people Acute adrenal failure, known as addisonian crisis Sometimes the symptoms of Addison's disease appear suddenly. Acute adrenal failure can lead to life-threatening shock. Seek emergency treatment for the following: Severe weakness Confusion Pain in the lower back or legs Severe abdominal pain, vomiting and diarrhea, leading to dehydration Reduced consciousness or delirium Low blood pressure",17,Addisons Disease "Symptoms include: Rough, dry or scaly patch of skin, usually less than 1 inch (2.5 centimeters) in diameter Flat to slightly raised patch or bump on the top layer of skin In some cases, a hard, wartlike surface Color variations, including pink, red or brown Itching, burning, bleeding or crusting New patches or bumps on sun-exposed areas of the head, neck, hands and forearms",10,Actinic Keratosis "yellow or green: Genital redness, burning and itching Pain with urination or sex Discomfort over the lower stomach area In men, trichomoniasis rarely causes symptoms. When men do have signs and symptoms, however, they might include: Itching or irritation inside the penis Burning with urination or after ejaculation Discharge from the penis",1011,Trichomoniasis "Signs and symptoms of hearing loss may include: Muffling of speech and other sounds Difficulty understanding words, especially against background noise or in a crowd Trouble hearing consonants Frequently asking others to speak more slowly, clearly and loudly Needing to turn up the volume of the television or radio Withdrawal from conversations Avoidance of some social settings",445,Hearing Loss "Mild forms of: Ebstein anomaly might not cause symptoms until later in adulthood. Signs and symptoms might include: Shortness of breath, especially with exertion Fatigue Heart palpitations or abnormal heart rhythms (arrhythmias) A bluish discoloration of the lips and skin caused by low oxygen (cyanosis)",328,Ebsteins Anomaly "Mild traumatic brain injury: The signs and symptoms of mild traumatic brain injury may include: Physical symptoms Headache Nausea or vomiting Fatigue or drowsiness Problems with speech Dizziness or loss of balance Sensory symptoms Sensory problems, such as blurred vision, ringing in the ears, a bad taste in the mouth or changes in the ability to smell Sensitivity to light or sound Cognitive, behavioral or mental symptoms Loss of consciousness for a few seconds to a few minutes No loss of consciousness, but a state of being dazed, confused or disoriented Memory or concentration problems Mood changes or mood swings Feeling depressed or anxious Difficulty sleeping Sleeping more than usual Moderate to severe traumatic brain injuries Moderate to severe traumatic brain injuries can include any of the signs and symptoms of mild injury, as well as these symptoms that may appear within the first hours to days after a head injury: Physical symptoms Loss of consciousness from several minutes to hours Persistent headache or headache that worsens Repeated vomiting or nausea Convulsions or seizures Dilation of one or both pupils of the eyes Clear fluids draining from the nose or ears Inability to awaken from sleep Weakness or numbness in fingers and toes Loss of coordination Cognitive or mental symptoms Profound confusion Agitation, combativeness or other unusual behavior Slurred speech Coma and other disorders of consciousness Children's symptoms Infants and young children with brain injuries might not be able to communicate headaches, sensory problems, confusion and similar symptoms. In a child with traumatic brain injury, you may observe: Change in eating or nursing habits Unusual or easy irritability Persistent crying and inability to be consoled Change in ability to pay attention Change in sleep habits Seizures Sad or depressed mood Drowsiness Loss of interest in favorite toys or activities",1008,Traumatic Brain Injury "Signs and symptoms of acute kidney failure may include: Decreased urine output, although occasionally urine output remains normal Fluid retention, causing swelling in your legs, ankles or feet Shortness of breath Fatigue Confusion Nausea Weakness Irregular heartbeat Chest pain or pressure Seizures or coma in severe cases Sometimes acute kidney failure causes no signs or symptoms and is detected through lab tests done for another reason.",554,Kidney Failure Signs and symptoms of lazy eye include: An eye that wanders inward or outward Eyes that appear to not work together Poor depth perception Squinting or shutting an eye Head tilting Abnormal results of vision screening tests Sometimes lazy eye is not evident without an eye exam.,566,Lazy Eye "Signs and symptoms of hypertrophic cardiomyopathy might include one or more of the following: Chest pain, especially during exercise Fainting, especially during or just after exercise or exertion Heart murmur, which a health care provider might detect while listening to the heart Sensation of fast, fluttering or pounding heartbeats (palpitations) Shortness of breath, especially during exercise",503,Hypertrophic Cardiomyopathy Signs and symptoms that are common to both: Crohn's disease and ulcerative colitis include: Diarrhea Fatigue Abdominal pain and cramping Blood in your stool Reduced appetite Unintended weight loss,522,Inflammatory Bowel Disease "The most common signs and symptoms of juvenile idiopathic arthritis are: Pain. While your child might not complain of joint pain, you may notice that he or she limps — especially first thing in the morning or after a nap. Swelling. Joint swelling is common but is often first noticed in larger joints such as the knee. Stiffness. You might notice that your child appears clumsier than usual, particularly in the morning or after naps. Fever, swollen lymph nodes and rash. In some cases, high fever, swollen lymph nodes or a rash on the trunk may occur — which is usually worse in the evenings. Juvenile idiopathic arthritis can affect one joint or many. There are several different subtypes of juvenile idiopathic arthritis, but the main ones are systemic, oligoarticular and polyarticular. Which type your child has depends on symptoms, the number of joints affected, and if a fever and rashes are prominent features. Like other forms of arthritis, juvenile idiopathic arthritis is characterized by times when symptoms flare up and times when symptoms may be minimal.",546,Juvenile Idiopathic Arthritis "Signs and symptoms of the condition include: Blackheads. Blackheads appear in small pitted areas of skin, often appearing in pairs. Painful pea-sized lumps. The condition usually starts with a single, painful lump under the skin that persists for weeks or months. More bumps may form later, usually in areas where you have more sweat and oil glands or where the skin rubs together, such as the armpits, groin, buttocks and breasts. Leaking bumps or sores. Some bumps or sores get bigger, break open and drain pus with an odor. Tunnels. Over time, tunnels might form under the skin, connecting the lumps. These wounds heal very slowly, if at all, and drain blood and pus. Some people with this condition experience only mild symptoms. The course of the disease is highly variable. Excess weight and being a smoker are associated with worse symptoms, but even people who are thin and don't smoke can experience severe disease.",474,Hidradenitis Suppurativa "Often the only sign of a hydrocele is a painless swelling of one or both testicles. The swelling might make an adult's scrotum feel heavy. In general, pain gets worse as the swelling increases. Sometimes, the swollen area might be smaller in the morning and larger later in the day.",492,Hydrocele "symptoms of pediatric sleep apnea might include: Snoring. Pauses in breathing. Restless sleep. Snorting, coughing or choking. Mouth breathing. Nighttime sweating. Bed-wetting. Sleep terrors. Infants and young children with obstructive sleep apnea don't always snore. They might just have disturbed sleep. During the day, children with sleep apnea might: Perform poorly in school. Have trouble paying attention. Have learning problems. Have behavioral problems. Have poor weight gain. Be hyperactive.",730,Pediatric Sleep Apnea "Signs and symptoms of ingrown hair include: Tiny, swollen bumps where you shave, tweeze or wax Small bumps that look like blisters or are filled with pus Small bumps that are darker than surrounding skin (hyperpigmentation) Burning or stinging Itching Hair in the shape of a loop because the tip of the hair curves and grows into the skin",524,Ingrown Hair "Some examples include: Feeling sad, hopeless or not enjoying things you used to enjoy Frequent crying Worrying or feeling anxious, nervous, jittery or stressed out Trouble sleeping Lack of appetite Difficulty concentrating Feeling overwhelmed Difficulty functioning in daily activities Withdrawing from social supports Avoiding important things such as going to work or paying bills Suicidal thoughts or behavior Symptoms of an adjustment disorder start within three months of a stressful event and last no longer than 6 months after the end of the stressful event. However, persistent or chronic adjustment disorders can continue for more than 6 months, especially if the stressor is ongoing, such as unemployment. When to see a doctor Usually stressors are temporary, and we learn to cope with them over time. Symptoms of adjustment disorder get better because the stress has eased. But sometimes the stressful event remains a part of your life. Or a new stressful situation comes up, and you face the same emotional struggles all over again. Talk to your doctor if you continue to struggle or if you're having trouble getting through each day. You can get treatment to help you cope better with stressful events and feel better about life again. If you have concerns about your child's adjustment or behavior, talk with your child's pediatrician. Suicidal thoughts or behavior If you have thoughts of hurting yourself or someone else, call 911 or your local emergency number immediately, go to an emergency room, or confide in a trusted relative or friend. Or contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline, available 24 hours a day, seven days a week. Or use the Lifeline Chat. Services are free and confidential.",20,Adjustment Disorders "A hamstring injury typically causes a sudden, sharp pain in the back of the thigh. There might also be a ""popping"" or tearing sensation. Swelling and tenderness usually develop within a few hours. There might be bruising or a change in skin color along the back of the leg. Some people have muscle weakness or are not able to put weight on the injured leg.",438,Hamstring Injury These may include: Seeing floating specks or cobwebs Blurred or distorted (straight lines look wavy) vision Defects in the side vision Lost vision You may need to try looking with each eye alone to notice these.,851,Retinal Diseases "Ameloblastoma often causes no symptoms, but signs and symptoms may include pain and a lump or swelling in the jaw. If left untreated, the tumor can grow very large, distorting the shape of the lower face and jaw and shifting teeth out of position.",39,Ameloblastoma "They may include: Persistent worrying or anxiety about a number of areas that are out of proportion to the impact of the events Overthinking plans and solutions to all possible worst-case outcomes Perceiving situations and events as threatening, even when they aren't Difficulty handling uncertainty Indecisiveness and fear of making the wrong decision Inability to set aside or let go of a worry Inability to relax, feeling restless, and feeling keyed up or on edge Difficulty concentrating, or the feeling that your mind ""goes blank"" Physical signs and symptoms may include: Fatigue Trouble sleeping Muscle tension or muscle aches Trembling, feeling twitchy Nervousness or being easily startled Sweating Nausea, diarrhea or irritable bowel syndrome Irritability There may be times when your worries don't completely consume you, but you still feel anxious even when there's no apparent reason. For example, you may feel intense worry about your safety or that of your loved ones, or you may have a general sense that something bad is about to happen. Your anxiety, worry or physical symptoms cause you significant distress in social, work or other areas of your life. Worries can shift from one concern to another and may change with time and age. Symptoms in children and teenagers Children and teenagers may have similar worries to adults, but also may have excessive worries about: Performance at school or sporting events Family members' safety Being on time (punctuality) Earthquakes, nuclear war or other catastrophic events A child or teen with excessive worry may: Feel overly anxious to fit in Be a perfectionist Redo tasks because they aren't perfect the first time Spend excessive time doing homework Lack confidence Strive for approval Require a lot of reassurance about performance Have frequent stomachaches or other physical complaints Avoid going to school or avoid social situations When to see a doctor Some anxiety is normal, but see your doctor if: You feel like you're worrying too much, and it's interfering with your work, relationships or other parts of your life You feel depressed or irritable, have trouble with drinking or drugs, or you have other mental health concerns along with anxiety You have suicidal thoughts or behaviors — seek emergency treatment immediately Your worries are unlikely to simply go away on their own, and they may actually get worse over time. Try to seek professional help before your anxiety becomes severe — it may be easier to treat early on.",408,Generalized Anxiety Disorder "Hay fever symptoms can include: Runny nose and nasal stuffiness (congestion) Watery, itchy, red eyes (allergic conjunctivitis) Sneezing Cough Itchy nose, roof of mouth or throat Mucus that runs down the back of your throat (postnasal drip) Swollen, bruised-appearing skin under the eyes (allergic shiners) Extreme tiredness (fatigue), often due to poor sleep Hay fever triggers Your hay fever signs and symptoms may occur year-round or may start or worsen at a particular time of year (seasonal). Hay fever triggers include: Tree pollen, which is common in early spring Grass pollen, which is common in late spring and summer Ragweed pollen, which is common in fall Dust mites and cockroach droppings, which are present year-round Dander from pets, which can be bothersome year-round but might cause worse symptoms in winter, when houses are closed up Spores from indoor and outdoor fungi and molds, which can be both seasonal and year-round Hay fever or common cold? Symptoms can be similar, so it can be difficult to tell which one you have. Condition Symptoms Onset Duration Hay fever Runny nose with thin, watery discharge; no fever Immediately after exposure to allergens As long as you're exposed to allergens Common cold Runny nose with watery or thick yellow discharge; body aches; low-grade fever 1 to 3 days after exposure to a cold virus 3 to 7 days",442,Hay Fever "You must have these signs and symptoms to be diagnosed with transient global amnesia: Sudden onset of confusion that includes memory loss, seen by a witness Being awake and alert and knowing who you are, despite memory loss Normal cognition, such as the ability to recognize and name familiar objects and follow simple directions No signs of damage to a particular area of the brain, such as being unable to move an arm or leg, movements you can't control, or problems understanding words More symptoms and history that may help diagnose transient global amnesia: Symptoms lasting no more than 24 hours and generally shorter Gradual return of memory No recent head injury No signs of seizures during the period of amnesia No history of active epilepsy Another common sign of transient global amnesia due to the inability to create new memories includes repetitive questioning, usually of the same question — for example, ""What am I doing here?"" or ""How did we get here?""",1004,Transient Global Amnesia "Depersonalization symptoms: Symptoms of depersonalization include: Feelings that you're an outside observer of your thoughts, feelings, your body or parts of your body — for example, as if you were floating in air above yourself Feeling like a robot or that you're not in control of your speech or movements The sense that your body, legs or arms appear distorted, enlarged or shrunken, or that your head is wrapped in cotton Emotional or physical numbness of your senses or responses to the world around you A sense that your memories lack emotion, and that they may or may not be your own memories Derealization symptoms Symptoms of derealization include: Feelings of being alienated from or unfamiliar with your surroundings — for example, like you're living in a movie or a dream Feeling emotionally disconnected from people you care about, as if you were separated by a glass wall Surroundings that appear distorted, blurry, colorless, two-dimensional or artificial, or a heightened awareness and clarity of your surroundings Distortions in perception of time, such as recent events feeling like distant past Distortions of distance and the size and shape of objects Episodes of depersonalization-derealization disorder may last hours, days, weeks or even months at a time. In some people, these episodes turn into ongoing feelings of depersonalization or derealization that may periodically get better or worse.",277,Depersonalization Derealization Disorder "In the lungs: After you swallow the tiny (microscopic) ascariasis eggs, they hatch in the small intestine and the larvae migrate through the bloodstream or lymphatic system into the lungs. At this stage, you may experience signs and symptoms similar to asthma or pneumonia, including: Persistent cough Shortness of breath Wheezing After spending 10 to 14 days in the lungs, the larvae travel to the throat, where you cough them up and then swallow them. In the intestines The larvae mature into adult worms in the small intestine, and the adult worms typically live in the intestines until they die. In mild or moderate ascariasis, the intestinal infestation can cause: Vague abdominal pain Nausea and vomiting Diarrhea or bloody stools If you have a large number of worms in the intestine, you might have: Severe abdominal pain Fatigue Vomiting Weight loss or malnutrition A worm in your vomit or stool",74,Ascariasis "They include: Chronic migraine Chronic tension-type headache New daily persistent headache Hemicrania continua Chronic migraine This type typically occurs in people with a history of episodic migraines. Chronic migraines tend to: Affect one side or both sides of your head Have a pulsating, throbbing sensation Cause moderate to severe pain And they cause at least one of the following: Nausea, vomiting or both Sensitivity to light and sound Chronic tension-type headache These headaches tend to: Affect both sides of your head Cause mild to moderate pain Cause pain that feels pressing or tightening, but not pulsating New daily persistent headache These headaches come on suddenly, usually in people without a headache history. They become constant within three days of your first headache. They: Often affect both sides of your head Cause pain that feels like pressing or tightening, but not pulsating Cause mild to moderate pain Might have features of chronic migraine or chronic tension-type headache Hemicrania continua These headaches: Affect only one side of your head Are daily and continuous with no pain-free periods Cause moderate pain with spikes of severe pain Respond to the prescription pain reliever indomethacin (Indocin) Can become severe with development of migraine-like symptoms In addition, hemicrania continua headaches are associated with at least one of the following: Tearing or redness of the eye on the affected side Nasal congestion or runny nose Drooping eyelid or pupil narrowing Sensation of restlessness",209,Chronic Daily Headaches "CRPS: Continuous burning or throbbing pain, usually in the arm, leg, hand or foot Sensitivity to touch or cold Swelling of the painful area Changes in skin temperature — alternating between sweaty and cold Changes in skin color, ranging from white and blotchy to red or blue Changes in skin texture, which may become tender, thin or shiny in the affected area Changes in hair and nail growth Joint stiffness, swelling and damage Muscle spasms, tremors and weakness (atrophy) Decreased ability to move the affected body part Symptoms may change over time and vary from person to person. Pain, swelling, redness, noticeable changes in temperature and hypersensitivity (particularly to cold and touch) usually occur first. Over time, the affected limb can become cold and pale. It may undergo skin and nail changes as well as muscle spasms and tightening. Once these changes occur, the condition is often irreversible. CRPS occasionally may spread from its source to elsewhere in the body, such as the opposite limb. CRPS In some people, signs and symptoms of CRPS go away on their own. In others, signs and symptoms may persist for months to years. Treatment is likely to be most effective when started early in the course of the illness.",257,Crps Complex Regional Pain Syndrome diabetes symptoms can appear suddenly and may include: Feeling more thirsty than usual Urinating a lot Bed-wetting in children who have never wet the bed during the night Feeling very hungry Losing weight without trying Feeling irritable or having other mood changes Feeling tired and weak Having blurry vision,1022,Type 1 Diabetes "They are typically: Situated just under the skin. They commonly occur in the neck, shoulders, back, abdomen, arms and thighs. Soft and doughy to the touch. They also move easily with slight finger pressure. Generally small. Lipomas are typically less than 2 inches (5 centimeters) in diameter, but they can grow. Sometimes painful. Lipomas can be painful if they grow and press on nearby nerves or if they contain many blood vessels.",578,Lipoma "Shingles: Shingles Shingles Shingles is characterized by pain or a tingling sensation in a limited area on one side of the face or torso, followed by a red rash with small, fluid-filled blisters. Shingles Shingles Shingles Shingles Shingles is characterized by pain or a tingling sensation in a limited area on one side of the face or torso, followed by a red rash with small, fluid-filled blisters. Shingles Shingles Shingles is characterized by pain or a tingling sensation in a limited area on one side of the face or torso, followed by a red rash with small, fluid-filled blisters. Shingles Shingles is characterized by pain or a tingling sensation in a limited area on one side of the face or torso, followed by a red rash with small, fluid-filled blisters. Shingles is characterized by pain or a tingling sensation in a limited area on one side of the face or torso, followed by a red rash with small, fluid-filled blisters. Shingles symptoms usually affect only a small section on one side of your body. These symptoms may include: Pain, burning or tingling Sensitivity to touch A red rash that begins a few days after the pain Fluid-filled blisters that break open and crust over Itching Some people also experience: Fever Headache Sensitivity to light Fatigue Pain is usually the first symptom of shingles. For some people, the pain can be intense. Depending on the location of the pain, it can sometimes be mistaken for problems with the heart, lungs or kidneys. Some people experience shingles pain without ever developing the rash. Most commonly, the shingles rash develops as a stripe of blisters that wraps around either the left or right side of the torso. Sometimes the shingles rash occurs around one eye or on one side of the neck or face.",904,Shingles "Salivary glands: Salivary glands Salivary glands There are three pairs of major salivary glands — parotid, sublingual and submandibular. Each gland has its own tube (duct) leading from the gland to the mouth. Salivary glands Salivary glands Salivary glands Salivary glands There are three pairs of major salivary glands — parotid, sublingual and submandibular. Salivary glands Salivary glands There are three pairs of major salivary glands — parotid, sublingual and submandibular. Salivary glands There are three pairs of major salivary glands — parotid, sublingual and submandibular. There are three pairs of major salivary glands — parotid, sublingual and submandibular. The two main symptoms of Sjogren's syndrome are: Dry eyes. Your eyes might burn, itch or feel gritty — as if there's sand in them. Dry mouth. Your mouth might feel like it's full of cotton, making it difficult to swallow or speak. Some people with Sjogren's syndrome also have one or more of the following: Joint pain, swelling and stiffness Swollen salivary glands — particularly the set located behind your jaw and in front of your ears Skin rashes or dry skin Vaginal dryness Persistent dry cough Prolonged fatigue",909,Sjogrens Syndrome "eating disorder include: Eating unusually large amounts of food in a specific amount of time, such as over a two-hour period Feeling that your eating behavior is out of control Eating even when you're full or not hungry Eating rapidly during binge episodes Eating until you're uncomfortably full Frequently eating alone or in secret Feeling depressed, disgusted, ashamed, guilty or upset about your eating Frequently dieting, possibly without weight loss Unlike a person with bulimia, after a binge, you don't regularly compensate for extra calories eaten by vomiting, using laxatives or exercising excessively. You may try to diet or eat normal meals. But restricting your diet may simply lead to more binge eating. The severity of binge-eating disorder is determined by how often episodes of bingeing occur during a week.",110,Binge Eating Disorder "Purpura around the eyes: Purpura around the eyes Purpura around the eyes Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin. This most commonly occurs around the eyes but can also affect other parts of the body. Purpura around the eyes Purpura around the eyes Purpura around the eyes Purpura around the eyes Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin. Purpura around the eyes Purpura around the eyes Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin. Purpura around the eyes Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin. Some people with amyloidosis experience purpura — a condition in which small blood vessels leak blood into the skin. Enlarged tongue Enlarged tongue Enlarged tongue An enlarged tongue (macroglossia) can be a sign of amyloidosis. It can sometimes also appear rippled along its edge. Enlarged tongue Enlarged tongue Enlarged tongue Enlarged tongue An enlarged tongue (macroglossia) can be a sign of amyloidosis. Enlarged tongue Enlarged tongue An enlarged tongue (macroglossia) can be a sign of amyloidosis. Enlarged tongue An enlarged tongue (macroglossia) can be a sign of amyloidosis. An enlarged tongue (macroglossia) can be a sign of amyloidosis. You may not experience symptoms of amyloidosis until later in the course of the disease. Symptoms may vary, depending on which organs are affected. Signs and symptoms of amyloidosis may include: Severe fatigue and weakness Shortness of breath Numbness, tingling, or pain in the hands or feet Swelling of the ankles and legs Diarrhea, possibly with blood, or constipation An enlarged tongue, which sometimes looks rippled around its edge Skin changes, such as thickening or easy bruising, and purplish patches around the eyes",43,Amyloidosis frequent bowel movements: Dark maroon or bright red blood in stool Narrow stool A feeling that your bowel doesn't empty completely Abdominal pain Unexplained weight loss Weakness or fatigue,840,Rectal Cancer "On brown and: Black skin, the bump often looks brown or glossy black. Tiny blood vessels might be visible, though they may be difficult to see on brown and Black skin. The bump may bleed and scab over. A brown, black or blue lesion — or a lesion with dark spots — with a slightly raised, translucent border. A flat, scaly patch with a raised edge. Over time, these patches can grow quite large. A white, waxy, scar-like lesion without a clearly defined border.",101,Basal Cell Carcinoma "Nausea, with or without vomiting, is common in pregnancy. Morning sickness is often brought on by smelling certain odors or eating certain foods. Morning sickness is most common during the first three months of pregnancy. It typically starts before nine weeks. Symptoms usually improve by the middle or end of the second three months of pregnancy.",646,Morning Sickness "Suicide warning signs or suicidal thoughts include: Talking about suicide — for example, making statements such as ""I'm going to kill myself,"" ""I wish I were dead"" or ""I wish I hadn't been born"" Getting the means to take your own life, such as buying a gun or stockpiling pills Withdrawing from social contact and wanting to be left alone Having mood swings, such as being emotionally high one day and deeply discouraged the next Being preoccupied with death, dying or violence Feeling trapped or hopeless about a situation Increasing use of alcohol or drugs Changing normal routine, including eating or sleeping patterns Doing risky or self-destructive things, such as using drugs or driving recklessly Giving away belongings or getting affairs in order when there's no other logical explanation for doing this Saying goodbye to people as if they won't be seen again Developing personality changes or being severely anxious or agitated, particularly when experiencing some of the warning signs listed above Warning signs aren't always obvious, and they may vary from person to person. Some people make their intentions clear, while others keep suicidal thoughts and feelings secret.",953,Suicide "common signs and symptoms include: High blood pressure Poor kidney function If the arteries affected supply blood to the brain, signs and symptoms might include: Headache Pulsating ringing in your ears (tinnitus) Dizziness Sudden neck pain Stroke or transient ischemic attack (TIA)",379,Fibromuscular Dysplasia Common symptoms are: Upset stomach. Vomiting. Diarrhea. Diarrhea with bloody stools. Stomach pain and cramps. Fever. Headache. Less often food poisoning affects the nervous system and can cause severe disease. Symptoms may include: Blurred or double vision. Loss of movement in limbs. Problems with swallowing. Tingling or numbness of skin. Weakness. Changes in sound of the voice.,386,Food Poisoning "and include: Itching and irritation in the vagina and vulva A burning sensation, especially during intercourse or while urinating Redness and swelling of the vulva Vaginal pain and soreness Vaginal rash Thick, white, odor-free vaginal discharge with a cottage cheese appearance Watery vaginal discharge Complicated yeast infection You might have a complicated yeast infection if: You have severe signs and symptoms, such as extensive redness, swelling and itching that leads to tears, cracks or sores You have four or more yeast infections in a year Your infection is caused by a less typical type of fungus You're pregnant You have uncontrolled diabetes Your immune system is weakened because of certain medications or conditions such as HIV infection",1078,Yeast Infection Heart palpitations can feel like the heart is: Beating too fast Flip-flopping Fluttering rapidly Pounding Skipping beats Heart palpitations may be felt in the throat or neck as well as the chest. They can occur during activity or at rest.,451,Heart Palpitations "Roseola: Roseola Roseola Roseola is a childhood illness caused by two strains of the herpes virus. Common signs of roseola are a fever and a rash on the trunk and neck. Roseola Roseola Roseola Roseola Roseola is a childhood illness caused by two strains of the herpes virus. Roseola Roseola Roseola is a childhood illness caused by two strains of the herpes virus. Roseola Roseola is a childhood illness caused by two strains of the herpes virus. Roseola is a childhood illness caused by two strains of the herpes virus. If your child is exposed to someone with roseola and becomes infected with the virus, it will likely take 1 to 2 weeks for signs and symptoms of infection to appear. Or they may not appear at all. It's possible to become infected with roseola but not show any sign of it. Roseola symptoms might include: Fever. Roseola often starts with a high fever — often higher than 103 F (39.4 C). It starts suddenly and lasts 3 to 5 days. Some children also may have a sore throat, runny nose or cough along with or before the fever. Your child may also develop swollen lymph nodes in the neck. Rash. After the fever goes away, a rash often appears. A roseola rash is many small spots or patches. These spots tend to be flat. The rash often starts on the chest, back and belly and then spreads to the neck and arms. It might reach the legs and face. The rash isn't likely to be itchy or painful. It can last hours or days. The rash might occur without a fever first. Other signs and symptoms of roseola may include: Irritability Mild diarrhea Decreased appetite Swollen eyelids",864,Roseola "Examples of signs and symptoms include: Feeling sad or down Confused thinking or reduced ability to concentrate Excessive fears or worries, or extreme feelings of guilt Extreme mood changes of highs and lows Withdrawal from friends and activities Significant tiredness, low energy or problems sleeping Detachment from reality (delusions), paranoia or hallucinations Inability to cope with daily problems or stress Trouble understanding and relating to situations and to people Problems with alcohol or drug use Major changes in eating habits Sex drive changes Excessive anger, hostility or violence Suicidal thinking Sometimes symptoms of a mental health disorder appear as physical problems, such as stomach pain, back pain, headaches, or other unexplained aches and pains.",618,Mental Illness "Heart failure: Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. Depending on your skin color, these color changes may be harder or easier to see. Some types of heart failure can lead to an enlarged heart. Heart failure Heart failure Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Heart failure Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Heart failure Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Heart failure occurs when the heart muscle doesn't pump blood as well as it should. If you have heart failure, your heart can't supply enough blood to meet your body's needs. Symptoms may develop slowly. Sometimes, heart failure symptoms start suddenly. Heart failure symptoms may include: Shortness of breath with activity or when lying down. Fatigue and weakness. Swelling in the legs, ankles and feet. Rapid or irregular heartbeat. Reduced ability to exercise. Wheezing. A cough that doesn't go away or a cough that brings up white or pink mucus with spots of blood. Swelling of the belly area. Very rapid weight gain from fluid buildup. Nausea and lack of appetite. Difficulty concentrating or decreased alertness. Chest pain if heart failure is caused by a heart attack.",449,Heart Failure "Children: The first sign of intussusception in an otherwise healthy infant may be sudden, loud crying caused by belly pain. Infants who have belly pain may pull their knees to their chests when they cry. The pain of intussusception comes and goes, usually every 15 to 20 minutes at first. These painful episodes last longer and happen more often as time passes. Other symptoms of intussusception include: Stool mixed with blood and mucus — sometimes referred to as currant jelly stool because of its appearance. Vomiting. A lump in the belly. Weakness or lack of energy. Diarrhea. Not everyone has all of the symptoms. Some infants have no obvious pain. Some children don't pass blood or have a lump in the belly. And some older children have pain but no other symptoms. Adults Intussusception is rare in adults. Also, because symptoms of the disorder often overlap with the symptoms of other disorders, it's more challenging to identify. The most common symptom is belly pain that comes and goes. Nausea and vomiting also may occur. People sometimes have symptoms for weeks before seeking medical attention.",534,Intussusception "They can include: Fatigue, lack of appetite or abdominal pain A yellowing of the skin and the whites of the eye (jaundice) Golden-brown eye discoloration (Kayser-Fleischer rings) Fluid buildup in the legs or abdomen Problems with speech, swallowing or physical coordination Uncontrolled movements or muscle stiffness When to see a doctor Make an appointment with your doctor if you have signs and symptoms that worry you, especially if a family member has Wilson's disease.",1072,Wilsons Disease "At first, you might barely notice the pain associated with a stress fracture, but it tends to worsen with time. The tenderness usually starts at a specific spot and decreases during rest. You might have swelling around the painful area.",945,Stress Fractures Symptoms of an anal fissure include: Pain during bowel movements. Pain after bowel movements that can last up to several hours. Bright red blood on the stool or toilet paper after a bowel movement. A visible crack in the skin around the anus. A small lump or skin tag on the skin near the anal fissure.,46,Anal Fissure "Signs and symptoms of stomach cancer may include: Trouble swallowing Belly pain Feeling bloated after eating Feeling full after eating small amounts of food Not feeling hungry when you would expect to be hungry Heartburn Indigestion Nausea Vomiting Losing weight without trying Feeling very tired Stools that look black Stomach cancer doesn't always cause symptoms in its early stages. When they happen, symptoms might include indigestion and pain in the upper part of the belly. Symptoms might not happen until the cancer is advanced. Later stages of stomach cancer might cause symptoms such as feeling very tired, losing weight without trying, vomiting blood and having black stools. Stomach cancer that spreads to other parts of the body is called metastatic stomach cancer. It causes symptoms specific to where it spreads. For example, when cancer spreads to the lymph nodes it might cause lumps you can feel through the skin. Cancer that spreads to the liver might cause yellowing of the skin and whites of the eyes. If cancer spreads within the belly, it might cause fluid to fill the belly. The belly might look swollen.",942,Stomach Cancer "Signs and symptoms of placental abruption include: Vaginal bleeding, although there might not be any Abdominal pain Back pain Uterine tenderness or rigidity Uterine contractions, often coming one right after another Abdominal pain and back pain often begin suddenly. The amount of vaginal bleeding can vary greatly, and doesn't necessarily indicate how much of the placenta has separated from the uterus. It's possible for the blood to become trapped inside the uterus, so even with a severe placental abruption, there might be no visible bleeding. In some cases, placental abruption develops slowly (chronic abruption), which can cause light, intermittent vaginal bleeding. Your baby might not grow as quickly as expected, and you might have low amniotic fluid or other complications.",762,Placental Abruption "Symptoms include pain that: Strikes suddenly and severely Peaks within 60 seconds Can be accompanied by nausea or vomiting Thunderclap headaches might be accompanied by other signs and symptoms, such as: Altered mental state Fever Seizures These signs and symptoms might reflect the underlying cause.",986,Thunderclap Headaches they may include: Yellowing of the skin and whites of the eyes (jaundice) Itching Abdominal pain in the upper right portion of the abdomen Fatigue Loss of appetite Nausea and vomiting Rash Fever Weight loss Dark or tea-colored urine,1000,Toxic Hepatitis "Branches of the trigeminal nerve: Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Branches of the trigeminal nerve Branches of the trigeminal nerve Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Branches of the trigeminal nerve Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Branches of the trigeminal nerve Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Trigeminal neuralgia results in pain occurring in an area of the face supplied by one or more of the three branches of the trigeminal nerve. Trigeminal neuralgia symptoms may include one or more of these patterns: Episodes of severe, shooting or jabbing pain that may feel like an electric shock Spontaneous attacks of pain or attacks triggered by things such as touching the face, chewing, speaking or brushing teeth Attacks of pain lasting from a few seconds to several minutes Pain that occurs with facial spasms Bouts of multiple attacks lasting days, weeks, months or longer — some people have periods when they experience no pain Pain in areas supplied by the trigeminal nerve, including the cheek, jaw, teeth, gums, lips, or less often the eye and forehead Pain affecting one side of the face at a time Pain focused in one spot or spread in a wider pattern Pain rarely occurring at night while sleeping Attacks that become more frequent and intense over time",1015,Trigeminal Neuralgia "Symptoms may include: Recurrent and excessive distress about anticipating or being away from home or loved ones Constant, excessive worry about losing a parent or other loved one to an illness or a disaster Constant worry that something bad will happen, such as being lost or kidnapped, causing separation from parents or other loved ones Refusing to be away from home because of fear of separation Not wanting to be home alone and without a parent or other loved one in the house Reluctance or refusing to sleep away from home without a parent or other loved one nearby Repeated nightmares about separation Frequent complaints of headaches, stomachaches or other symptoms when separation from a parent or other loved one is anticipated Separation anxiety disorder may be associated with panic disorder and panic attacks ― repeated episodes of sudden feelings of intense anxiety and fear or terror that reach a peak within minutes.",895,Separation Anxiety Disorder "the symptoms of bronchiolitis are much like a cold: Runny nose. Stuffy nose. Cough. Sometimes a slight fever. Later, your child may have a week or more of working harder than usual to breathe, which may include wheezing. Many infants with bronchiolitis also have an ear infection called otitis media.",150,Bronchiolitis "Intrusive memories: Intrusive memories Symptoms of intrusive memories may include: Recurrent, unwanted distressing memories of the traumatic event Reliving the traumatic event as if it were happening again (flashbacks) Upsetting dreams or nightmares about the traumatic event Severe emotional distress or physical reactions to something that reminds you of the traumatic event Avoidance Avoidance Symptoms of avoidance may include: Trying to avoid thinking or talking about the traumatic event Avoiding places, activities or people that remind you of the traumatic event Negative changes in thinking and mood Negative changes in thinking and mood Symptoms of negative changes in thinking and mood may include: Negative thoughts about yourself, other people or the world Hopelessness about the future Memory problems, including not remembering important aspects of the traumatic event Difficulty maintaining close relationships Feeling detached from family and friends Lack of interest in activities you once enjoyed Difficulty experiencing positive emotions Feeling emotionally numb Changes in physical and emotional reactions Changes in physical and emotional reactions Symptoms of changes in physical and emotional reactions (also called arousal symptoms) may include: Being easily startled or frightened Always being on guard for danger Self-destructive behavior, such as drinking too much or driving too fast Trouble sleeping Trouble concentrating Irritability, angry outbursts or aggressive behavior Overwhelming guilt or shame For children 6 years old and younger, signs and symptoms may also include: Re-enacting the traumatic event or aspects of the traumatic event through play Frightening dreams that may or may not include aspects of the traumatic event Intensity of symptoms Intensity of symptoms PTSD symptoms can vary in intensity over time. You may have more PTSD symptoms when you're stressed in general, or when you come across reminders of what you went through. For example, you may hear a car backfire and relive combat experiences. Or you may see a report on the news about a sexual assault and feel overcome by memories of your own assault. When to see a doctor When to see a doctor If you have disturbing thoughts and feelings about a traumatic event for more than a month, if they're severe, or if you feel you're having trouble getting your life back under control, talk to your doctor or a mental health professional. Getting treatment as soon as possible can help prevent PTSD symptoms from getting worse. If you have suicidal thoughts If you have suicidal thoughts If you or someone you know has suicidal thoughts, get help right away through one or more of these resources: Reach out to a close friend or loved one. Contact a minister, a spiritual leader or someone in your faith community. Contact a suicide hotline. In the U.S., call or text 988 to reach the 988 Suicide & Crisis Lifeline, available 24 hours a day, seven days a week. Or use the Lifeline Chat. Services are free and confidential. Make an appointment with your doctor or a mental health professional. When to get emergency help When to get emergency help If you think you may hurt yourself or attempt suicide, call 911 or your local emergency number immediately. If you know someone who's in danger of attempting suicide or has made a suicide attempt, make sure someone stays with that person to keep him or her safe. Call 911 or your local emergency number immediately. Or, if you can do so safely, take the person to the nearest hospital emergency room.",783,Post Traumatic Stress Disorder "Your health care provider may also suspect a problem if you have: High blood pressure that begins suddenly or worsens without explanation High blood pressure that begins before age 30 or after age 50 As renal artery stenosis progresses, other signs and symptoms may include: High blood pressure that's hard to control A whooshing sound as blood flows through a narrowed vessel (bruit), which your doctor hears through a stethoscope placed over your kidneys Elevated protein levels in the urine or other signs of a problem with kidney function Worsening kidney function during treatment for high blood pressure Fluid overload and swelling in your body's tissues Treatment-resistant heart failure When to seek medical advice Make an appointment with your doctor if you have any persistent signs or symptoms that worry you.",847,Renal Artery Stenosis "Symptoms might include: Pain. Most people who develop optic neuritis have eye pain that's worsened by eye movement. Sometimes the pain feels like a dull ache behind the eye. Vision loss in one eye. Most people have at least some temporary reduction in vision, but the extent of loss varies. Noticeable vision loss usually develops over hours or days and improves over several weeks to months. Vision loss is permanent in some people. Visual field loss. Side vision loss can occur in any pattern, such as central vision loss or peripheral vision loss. Loss of color vision. Optic neuritis often affects color perception. You might notice that colors appear less vivid than normal. Flashing lights. Some people with optic neuritis report seeing flashing or flickering lights with eye movements.",695,Optic Neuritis "cell lymphoma include: Round patches of skin that may be raised or scaly and might be itchy Patches of skin that appear lighter in color than surrounding skin Lumps that form on the skin and may break open Enlarged lymph nodes Hair loss Thickening of the skin on the palms of the hands and soles of the feet A rash-like skin redness over the entire body that is intensely itchy Causes The exact cause of cutaneous T-cell lymphoma isn't known. In general, cancer begins when cells develop changes (mutations) in their DNA. A cell's DNA contains instructions that tell a cell what to do. The DNA mutations tell the cells to grow and multiply rapidly, creating many abnormal cells. In cutaneous T-cell lymphoma, the mutations cause too many abnormal T cells that attack the skin. T cells are part of your immune system, and they normally help your body fight germs. Doctors don't know why the cells attack the skin. By Mayo Clinic Staff By Mayo Clinic Staff Cutaneous T-cell lymphoma care at Mayo Clinic",261,Cutaneous T Cell Lymphoma signs and symptoms may include: Bone pain Easy bleeding Feeling full after eating a small amount of food Feeling run-down or tired Fever Weight loss without trying Loss of appetite Pain or fullness below the ribs on the left side Excessive sweating during sleep (night sweats),216,Chronic Myelogenous Leukemia "invasive lobular carcinoma may cause: An area of thickening in part of the breast A new area of fullness or swelling in the breast A change in the texture or appearance of the skin over the breast, such as dimpling or thickening A newly inverted nipple Invasive lobular carcinoma is less likely than other forms of breast cancer to cause a firm or distinct breast lump.",535,Invasive Lobular Carcinoma "Breast growth and first period in girls: Enlarged testicles and penis, facial hair and deepening voice in boys Pubic or underarm hair Rapid growth Acne Adult body odor",791,Precocious Puberty Medication overuse headaches tend to: Occur every day or nearly every day. They often wake you in the early morning. Improve with pain medicine but then return as the medicine wears off. Other symptoms may include: Nausea. Restlessness. Trouble concentrating. Memory problems. Irritability.,608,Medication Overuse Headache "Parts of the immune system: Parts of the immune system Parts of the immune system The lymphatic system is part of the body's immune system, which protects against infection and disease. The lymphatic system includes the spleen, thymus, lymph nodes and lymph channels, as well as the tonsils and adenoids. Parts of the immune system Parts of the immune system Parts of the immune system Parts of the immune system The lymphatic system is part of the body's immune system, which protects against infection and disease. Parts of the immune system Parts of the immune system The lymphatic system is part of the body's immune system, which protects against infection and disease. Parts of the immune system The lymphatic system is part of the body's immune system, which protects against infection and disease. The lymphatic system is part of the body's immune system, which protects against infection and disease. Leg lymphedema Leg lymphedema Leg lymphedema Lymphedema is swelling in an arm or a leg. In rare circumstances, it affects both arms or both legs. It can also affect the chest wall and abdomen. Leg lymphedema Leg lymphedema Leg lymphedema Leg lymphedema Lymphedema is swelling in an arm or a leg. Leg lymphedema Leg lymphedema Lymphedema is swelling in an arm or a leg. Leg lymphedema Lymphedema is swelling in an arm or a leg. Lymphedema is swelling in an arm or a leg. Lymphedema signs and symptoms include: Swelling of part or all of the arm or leg, including fingers or toes A feeling of heaviness or tightness Restricted range of motion Recurring infections Hardening and thickening of the skin (fibrosis) Signs and symptoms can range from mild to severe. Lymphedema caused by cancer treatment may not occur until months or years after treatment.",593,Lymphedema "Where skin cancer develops: Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma is a type of skin cancer that most often develops on areas of skin exposed to the sun, such as the face. On white skin, basal cell carcinoma often looks like a bump that's skin-colored or pink. Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma is a type of skin cancer that most often develops on areas of skin exposed to the sun, such as the face. Basal cell carcinoma on white skin Basal cell carcinoma on white skin Basal cell carcinoma is a type of skin cancer that most often develops on areas of skin exposed to the sun, such as the face. Basal cell carcinoma on white skin Basal cell carcinoma is a type of skin cancer that most often develops on areas of skin exposed to the sun, such as the face. Basal cell carcinoma is a type of skin cancer that most often develops on areas of skin exposed to the sun, such as the face. Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Sun-exposed areas such as the lips and ears are especially likely to develop squamous cell carcinoma of the skin. Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Sun-exposed areas such as the lips and ears are especially likely to develop squamous cell carcinoma of the skin. Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin Sun-exposed areas such as the lips and ears are especially likely to develop squamous cell carcinoma of the skin. Squamous cell carcinoma of the skin Sun-exposed areas such as the lips and ears are especially likely to develop squamous cell carcinoma of the skin. Sun-exposed areas such as the lips and ears are especially likely to develop squamous cell carcinoma of the skin. Melanoma Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. This melanoma shows color variations and an irregular border, both of which are melanoma warning signs. Melanoma Melanoma Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. Melanoma Melanoma The first sign of melanoma is often a mole that changes size, shape or color. Melanoma The first sign of melanoma is often a mole that changes size, shape or color. The first sign of melanoma is often a mole that changes size, shape or color. Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma is a rare, aggressive skin cancer. It appears as a painless, flesh-colored or bluish-red nodule growing on your skin. Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma is a rare, aggressive skin cancer. Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma is a rare, aggressive skin cancer. Merkel cell carcinoma Merkel cell carcinoma is a rare, aggressive skin cancer. Merkel cell carcinoma is a rare, aggressive skin cancer. Skin cancer develops primarily on areas of sun-exposed skin, including the scalp, face, lips, ears, neck, chest, arms and hands, and on the legs in women. But it can also form on areas that rarely see the light of day — your palms, beneath your fingernails or toenails, and your genital area. Skin cancer affects people of all skin tones, including those with darker complexions. When melanoma occurs in people with dark skin tones, it's more likely to occur in areas not normally exposed to the sun, such as the palms of the hands and soles of the feet. Basal cell carcinoma signs and symptoms Basal cell carcinoma usually occurs in sun-exposed areas of your body, such as your neck or face. Basal cell carcinoma may appear as: A pearly or waxy bump A flat, flesh-colored or brown scar-like lesion A bleeding or scabbing sore that heals and returns Squamous cell carcinoma signs and symptoms Most often, squamous cell carcinoma occurs on sun-exposed areas of your body, such as your face, ears and hands. People with darker skin are more likely to develop squamous cell carcinoma on areas that aren't often exposed to the sun. Squamous cell carcinoma may appear as: A firm, red nodule A flat lesion with a scaly, crusted surface Melanoma signs and symptoms Melanoma can develop anywhere on your body, in otherwise normal skin or in an existing mole that becomes cancerous. Melanoma most often appears on the face or the trunk of affected men. In women, this type of cancer most often develops on the lower legs. In both men and women, melanoma can occur on skin that hasn't been exposed to the sun. Melanoma can affect people of any skin tone. In people with darker skin tones, melanoma tends to occur on the palms or soles, or under the fingernails or toenails. Melanoma signs include: A large brownish spot with darker speckles A mole that changes in color, size or feel or that bleeds A small lesion with an irregular border and portions that appear red, pink, white, blue or blue-black A painful lesion that itches or burns Dark lesions on your palms, soles, fingertips or toes, or on mucous membranes lining your mouth, nose, vagina or anus Signs and symptoms of less common skin cancers Other, less common types of skin cancer include: Kaposi sarcoma. This rare form of skin cancer develops in the skin's blood vessels and causes red or purple patches on the skin or mucous membranes. Kaposi sarcoma mainly occurs in people with weakened immune systems, such as people with AIDS, and in people taking medications that suppress their natural immunity, such as people who've undergone organ transplants. Other people with an increased risk of Kaposi sarcoma include young men living in Africa or older men of Italian or Eastern European Jewish heritage. Merkel cell carcinoma. Merkel cell carcinoma causes firm, shiny nodules that occur on or just beneath the skin and in hair follicles. Merkel cell carcinoma is most often found on the head, neck and trunk. Sebaceous gland carcinoma. This uncommon and aggressive cancer originates in the oil glands in the skin. Sebaceous gland carcinomas — which usually appear as hard, painless nodules — can develop anywhere, but most occur on the eyelid, where they're frequently mistaken for other eyelid problems.",910,Skin Cancer