adding short model card

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by clem HF Staff - opened
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  1. README.md +31 -3
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- license: mit
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+ ---
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+ license: mit
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+ tags:
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+ - biology
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+ - chemistry
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+ - protein-structure
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+ - binding-affinity
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+ - drug-discovery
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+ - biomolecular-modeling
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+ - boltz
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+ - boltz-2
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+ - deep-learning
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+ - structural-biology
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+ ---
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+ # Boltz-2: Accurate and Efficient Biomolecular Interaction Prediction
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+ **Boltz-2** is an open-source deep learning model for biomolecular interaction prediction, developed by researchers at MIT and Recursion. It extends the capabilities of its predecessor, Boltz-1, by jointly modeling complex 3D structures and binding affinities, achieving near-physics-based accuracy while operating approximately 1000 times faster than traditional methods. This advancement makes accurate *in silico* screening practical for early-stage drug discovery.
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+ ## 🧬 Model Overview
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+ Boltz-2 is designed to predict:
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+ - **3D structures** of biomolecular complexes, including proteins, RNA, DNA, and small molecules.
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+ - **Binding affinities**, providing insights into molecular interactions critical for drug design.
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+ Key features:
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+ - **Joint Modeling**: Simultaneously predicts structural conformations and binding affinities.
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+ - **Speed and Efficiency**: Achieves near-free energy perturbation (FEP) accuracy with significantly reduced computational requirements.
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+ - **Open-Source**: Released under the MIT license, encouraging both academic and commercial use.