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9,100
ProMED update
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Infectious disease surveillance update
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Subject index volume 7 international journal of infectious diseases
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Other: Impact and consequences of attending the Canadian Pain Society annual conference in Toronto during the SARS crisis: Survey of delegates
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OP3-4 Alternative method for airborne virus detection in only few hours/innovative microbial air sampler
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Evaluation of the new NucliSens easyMAG(®) nucleic acid extraction system
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Self Collection of Nasal Swabs for Diagnosis of Respiratory Viruses in Immunocompetent Volunteers and Hematopoietic Stem Cell Transplant (HCT) Recipients
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Prevalence of two recently described HBV mutations and their effect on adefovir therapy
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PP-181 A novel 2-tailed CUSUM control-chart for evaluating new therapies: hypertonic-saline in bronchiolitis compared to nebulized adrenaline
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486. Plasmid DNA Constructs Expressing SARS-CoV Antigens Are Immunogenic in Mice and Rabbits
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Technology and public health
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Asia takes action on drug-resistant tuberculosis
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O.7.6 Enhanced etiological diagnosis of respiratory virus infections and outbreaks using nucleic acid amplification testing against an expanded range of targets
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Neuroinfection & neuroimmunology: New opportunities, new challenges
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37: Incidence of Upper and Lower Airway Viral Infections in a Cohort of Lung Transplant Recipients (LTRs)
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HealthMap: the future of infectious diseases surveillance?
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320. Selection of Lentiviral Vectors for Gene Transfer to Porcine Airways
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CS15-01 Can We Prevent Hepatocellular Carcinoma in Chronic Hepatitis B?
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Papers to Appear in Forthcoming Issues
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M-III Laboratory diagnosis of viral gastroenteritis
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Infectious disease surveillance update
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Diagnosis of human metapneumovirus by immunofluorescence-the newcastle experience
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Non-traditional outbreak surveillance - the 15 year experience
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PP-178 Surveillance of antimicrobial resistance in patients with community acquired pneumonia in tertiary care hospital, Manipal
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PI-6 West Nile virus (WNV) seroprevalence in blood donors from Central Anatolia
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Infectious diseases: A never-ending threat
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Free Communications (Poster Sessions)
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The innovative qiasymphony system from Qiagen takes ease of use to a new level
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Corrections
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13th International Congress on Infectious Diseases Abstracts (Oral Presentations)
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RNA Virus Vectors
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O.7.7 Impact of duration of illness on viral load and detection rate of viral pathogens by multiplex PCR in respiratory tract infections
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Exotic Viral Diseases: A Global Guide: S.A. Berger, C.H. Calisher and J.S. Keystone; BC Decker – Inc, Hamilton and London, 2003, 252 pages, Paperback, ISBN 1-55009-205-7 ($29.95)
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OP3-1 Evaluation of Clart® Pneumovir DNA arrays for the detection of respiratory viruses among children hospitalised in intensive care unit
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Methylation profile of bovine Oct4 gene coding region in relation to three germ layers
Previous studies have shown that octamer-binding transcription factor 4 (Oct4) plays a significant role in early embryonic development of mammalian animals, and different Oct4 expression levels induce multi-lineage differentiation which are regulated by DNA methylation. To explore the relationship between the methylation pattern of Oct4 gene exon 1 and embryonic development, in this work, five different tissues (heart, liver, lung, cerebrum and cerebellum) from three germ layers were chosen from low age (50–60 d) and advanced age (60–70 d) of fetal cattle and the differences between tissues or ages were analyzed, respectively. The result showed that the DNA methylation level of Oct4 gene exon 1 was significant different (P<0.01) between any two of three germ layers in low age (<60 d), but kept steady of advanced age (P>0.05) (>60 d), suggesting that 60-d post coital was an important boundary for embryonic development. In addition, in ectoderm (cerebrum and cerebellum), there was no significant methylation difference of Oct4 gene exon 1 between low age and advanced age (P>0.05), but the result of endoderm (liver and lung) and mesoderm (heart) were on the contrary (P<0.01), which indicated the development of ectoderm was earlier than endoderm and mesoderm. The methylation differences from the 3rd, 5th and 9th CpG-dinucleotide loci of Oct4 gene exon 1 were significantly different between each two of three germ layers (P<0.05), indicating that these three loci may have important influence on bovine embryonic development. This study showed that bovine germ layers differentiation was significantly related to the DNA methylation status of Oct4 gene exon 1. This work firstly identified the DNA methylation profile of bovine Oct4 gene exon 1 and its association with germ layers development in fetus and adult of cattle. Moreover, the work also provided epigenetic information for further studying bovine embryonic development and cellular reprogramming.
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JOGC Guidelines index English
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152* Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs
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Human herpesvirus-6 viraemia in children with primary immunodeficiency undergoing stem-cell-transplantation
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Summaries
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Poster Presentations
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À propos du COVD-19 : note de l’éditeur et des rédacteurs en chef de la revue GOFS
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Evaluation of Infection Risk Factors in Adult Hematologic Malignancy Patients
INTRODUCTION: Hematologic malignancies (HM) are often highly aggressive processes requiring multi-chemotherapy regimens and potentially hematopoietic stem cell transplant (HSCT) for treatment. Totally implantable venous access ports (TIVAP) are the standard access for administration of these regimens. The regimens usually involve periods of neutropenia for which infection can increase morbidity and require removal of the port. Although deemed safe for use in cancer populations, many studies have only looked at patients with TIVAP in solid tumor malignancies. Herein, we report our single institution experience identifying modulators for infection related to TIVAP in this high-risk population. OBJECTIVES: To identify risk factors for port infection in HM patients. METHODS: We performed an IRB-approved single institution retrospective review of HM patients who had a TIVAP removed for port infection versus completion of therapy. Medical records were evaluated for patient demographics and tumor type, details of previous therapy regimens such as chemotherapy and HSCT status, laboratory values including albumin, white blood cell, neutrophil and platelet counts, as well as characteristics of the TIVAP. Univariate and multivariate regression analyses were performed between the two cohorts to identify clinical predictors of port infection necessitating TIVAP removal. RESULTS: Between March 2015 and July 2018, 104 TIVAPs were removed from HM patients, 34 (33%) for infection and 70 (67%) for completion of treatment. Median patient age was 60 years (range 22-86) and there was an even number of men and women (n=52). Most TIVAPs were double lumen (n=98, 94%) and placed in the right IJV (n=100, 96%). The median number of port days was 49 in the infection group and 414 in the completion group, with removal of 12 (35%) of the infected ports within 30 days. Multiple factors were significant predictors of port infection on univariate analysis, including diagnosis of AML or ALL (p=0.0019), no prior HSCT (p=0.0148), neutropenia within 30 days of removal (p<0.0001), ANC <1500 (p <0.0001), leukopenia the day prior to removal (p<0.0001), thrombocytopenia (p <0.0001), and hypoalbuminemia (p<0.0001). Steroid use, leukopenia or leukocytosis the day of placement, and leukocytosis the day prior to removal were not significantly different between the two groups. On multivariate analysis, no prior HSCT (OR=48.08, 95% CI 2.64-875.63, p=0.009), neutropenia within 30 days of removal (OR=67.60, 95% CI 1.68-2726.66, p=0.026), and hypoalbuminemia (OR=405.52, 95% CI 15.64-10517.89, p<0.0001) remained significant. CONCLUSION: In patients with HM, significant predictors of port infection requiring TIVAP removal included neutropenia within 30 days of removal and hypoalbuminemia. Interestingly, patients who underwent HSCT were less likely to a develop a port infection requiring TIVAP removal.
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Abstracts accepted for publication only
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M-I Submitting an article to Journal of Clinical Virology
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Update to the Latin American Thoracic Society (ALAT) Recommendations on Community-Acquired Pneumonia
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Multiplex real time PCRs for respiratory viral infections
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P441 – P678
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Membrane protein expression made easy: Gong, F-C., Giddings, T.H., Meehl, J.B., Staehelin, L.A. and Galbraith, D.W. (1996) Z-membranes: artificial organelles for overexpressing recombinant integral membrane proteins, Proc. Natl Acad. Sci. USA 93, 2219–2223
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P175 Extended incubation of cystic fibrosis cultures: is it worth it?
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Forum
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Infectious disease surveillance update
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PI-4 Rat-to-human cowpoxvirus outbreaks, France 2009
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Summaries
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P.060 Influenza A viruses host ultrastructural nuclear modifications: specific different patterns between avian and human strains?
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Contents page.
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Microbead array based technology for detection and quantitation of viral respiratory pathogens associated with pneumonia among children
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Health activists in China unlawfully discriminated against
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Innate Immunity to Pulmonary Infection, Novartis Foundation series No. 279
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DNA ladders connecting animals and plants: Ryerson, D.E. and Heath, M.C. (1996) Cleavage of nuclear DNA into oligonucleosomal fragments during cell death induced by fungal infection or by abiotic treatments, Plant Cell 8, 393–402 Wang, H., Li, J., Bostock, R.M. and Gilchrist, D.G. (1996) Apoptosis: a functional paradigm for programmed plant cell death induced by a host-selective phytotoxin and invoked during development, Plant Cell 8, 375–391
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Infectious disease surveillance update
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Author/Title Index
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L’usage des corticoïdes en réanimation
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Subject Index: 2004: Volume 26, Numbers 1–12
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PIV-2 The Ibis T5000 for high-throughput identification and discrimination of the pandemic H1N1 influenza virus in Chicago
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Polyhydroxybutyrate microarray for immunodiagnostics and pathogen detections by immobilizing fusion proteins
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PI-8 Vaccine induced and naturally acquired antibodies against mumps virus
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Author index of Volume 7
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CS15.1 CMV in transplant recipients
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I-48 The clinical characteristics and therapy for SARS
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The role of diabetes in the severity of 2009 influenza A (H1N1) and the Middle East respiratory syndrome coronavirus (MERS-CoV): A systematic review and meta-analysis
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Chapter 2 Biogenesis and Sorting of Plasma Membrane Proteins
The cell surface membrane is the boundary between a cell and its environment. In case of polarized epithelial cells, the apical plasma membrane is frequently the boundary between an organism and its environment. The plasmalemma possesses the elements that endow a cell with the capacity to converse with its environment. Plasmalemmal receptor and transducer proteins allow the cell to recognize and respond to various external influences. Membrane-associated proteins anchor cells to their substrata and mediate their integration into tissues. Many properties of a given cell type may be attributed to the protein composition of its plasma membrane. Most cells go to large lengths to control the nature and distribution of polypeptides that populate their plasmalemmas. Cells regulate the expression of genes encoding plasma membrane proteins. Proteins destined for the insertion into the plasma membrane pass through a complex system of processing organelles prior to arriving at their site of ultimate functional residence. Each of these organelles makes a unique contribution to the maturation of these proteins as they transit through them. This chapter discusses the postsynthetic steps involved in the biogenesis of plasma membrane proteins. The chapter discusses some of the events common to all plasmalemmal polypeptides, with special emphasis on those that contribute directly to the character of the cell surface. The chapter then discusses the specializations, associated with cell types, possessing differentiated cell surface sub-domains. The chapter highlights some of the important and fascinating questions confronting investigators interested in the cell biology of the plasma membrane.
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Infectious disease surveillance update
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Control of Virus-\associated Hemophagocytic Syndrome by Peroxisome Proliferator Activated Receptor Agonists in a Rabbit Model
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P174 High aerosol production of potentially infectious cough aerosols in people with cystic fibrosis during coughing
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OP3-5 Possible independent replication of HBV in the CNS of HIV-1 infected patients
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Recently in The Lancet
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PIV-25 Phylogenetic analysis of Italian human metapneumovirus (HMPV) and human bocavirus (HBOV) strains
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Particles, aerosols, and their transport in the built environment
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SARS sequencing paves the way for better diagnostics
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PIV-27 Viral pathogens of respiratory tract infections in Ankara, Turkey
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Pandemic: tracking contagions
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B5/133 – Longer-term follow up of aerobic capacity in children affected by Severe Acute Respiratory Syndrome (SARS)
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Development and validation of different indirect ELISAs for MERS-CoV serological testing
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Infectious disease surveillance update
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PIV-35 Evaluation of two newly developed QIAsymphony sp protocols for efficient isolation of influenza virus RNA from different respiratory samples
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I-59 The interaction between M1 protein of influenza virus and host cell factors
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Subject index of Volume 5
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No end in sight to SARS
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Naturally-occurring hepatitis C virus protease variants: implications for resistance to new antivirals
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European lab network prepares for high-risk pathogen threat
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PP-179 Preparation of overlapping peptides of human being' SARS virus M protein and its application as diagnose SARS
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Bodysnatchers
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From Anthrax to Zika: memoirs of a disease detective
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Multiple introductions of MERS-CoV in a 2014 hospital outbreak in Riyadh, Saudi Arabia
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Erratum
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Global early warning signs for health threats at the human animal ecosystem interface
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Infectious disease surveillance update
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CDC updates quarantine rules
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RNAi Delivered across the Blood-Brain Barrier
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Keyword index, Volume 31 (2007)
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