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In a mountainous trade corridor once reliant on pack animals, a French traveler’s albumen photo in a major museum shows a metal-beam crossing over a small river within a portfolio that also includes scenes from far northern cities. On the same route, the tightest curve later had people walking trains as they moved under wires. Decades afterward, a much taller replacement rose nearby during a modernization, leaving the earlier curved structure visible but unused. What is the name of that crossing?
web
600
en
At a global multi-sport gathering marked by many withdrawals, a men’s team in a ball game departed after its first match, causing the rest of its fixtures to be recorded without play. From the same delegation, a competitor in a weight‑classified combat sport won his opener by referee intervention but did not appear for his next scheduled bout. Meanwhile, a sprinter from a small state asked to compete without national affiliation but was refused. What is the full name of the first opponent defeated by that combat athlete?
web
601
en
在襄阳市有一处景观区,满足以下特征: 1. 位于保康县城关镇 2. 从襄阳站出发至该地的导航距离约为131.01公里 3. 暂无从襄阳站前往该地的公共交通线路可用 请问这个景观区的名称是什么?
map
602
zh
Identify the U.S.-listed company that meets all the following conditions: 1) It is an SEC registrant that filed its Q2 2025 report on July 31, 2025 (accepted July 30, 2025). 2) For Q2 2025 (period ending June 30, 2025), it reported revenue of approximately $5.898 billion and positive net income, with diluted EPS around $0.2365 and about 2.203 billion diluted shares outstanding. 3) For Q1 2025 (period ending March 31, 2025), it reported revenue of approximately $5.983 billion and positive net income. What is its ticker symbol?
finance
603
en
Identify a US-listed company that meets all these conditions: 1. Its headquarters is located in California, and it operates in the Utilities sector. 2. Its revenue in Q2 2025 was $0 USD (pre-revenue) while reporting a net loss exceeding $20 million USD in the same quarter. 3. Its stock price increased by over 200% from January 2, 2025 to July 31, 2025, vastly outperforming the S&P 500 index's growth during the same period. 4. The company had a debt-to-equity ratio below 10% in its latest quarterly balance sheet (as of Q2 2025).
finance
604
en
On YouTube, there is a video that meets all of the following conditions: 1) Streamed live on September 7, 2025; 2) The channel has more than 3k subscribers as of 2025-09; 3) A top comment includes the exact phrase "villa absolutely cooked"; 4) The channel's description mentions creating "eFootball content for all Africans and Kenyans". Which video is this? Provide its URL.
video
605
en
A clinical trial is described by the following characteristics. What is the NCT ID of this trial? 1. This is a randomized, triple-blinded, placebo-controlled pilot trial designed as a type 1 hybrid efficacy-implementation study, focusing on maternal mental health and caregiver-child dynamics. 2. The study includes female participants who are in treatment for substance use and are primary caregivers of preschool-aged children, with an expected enrollment of approximately 200 individuals. 3. Primary outcome measures involve validated assessments of parental mentalization and stress levels, collected at baseline and after the intervention period. 4. The trial is conducted at a research site in Western Massachusetts with an anticipated duration of approximately four years starting in late 2025. 5. The trial is funded by a non-profit organization rather than a university or industry entity. Which clinical trial identifier matches all these criteria?
bio
606
en
Identify a U.S.-listed healthcare company that meets all the following conditions: 1. Headquartered in Pennsylvania (as per latest SEC filings) 2. Fiscal year 2024 annual revenue exceeded $14.5 billion but was below $15.5 billion 3. Reported a negative net income for the full fiscal year 2024. 4. Stock price increased between 5% and 7% over the 6-month period leading up to September 19, 2025.
finance
607
en
A slim booklet of verse once languished until a friend bought extra copies and handed one to a painter-poet, drawing an artists’ circle to it. Later, a devoted reader formed a dining club around those lines, kept its notes for two decades, then chaired it. The same person also engineered a record-small printing, fitting 46 four-line pieces from a favored rendition into a tiny volume. Who is he?
web
608
en
在海南省三沙市南沙区,存在一处地貌类型为“暗沙”的海上地物。现给出两个参照坐标点:点1为112.959177,9.636223,点2为115.536360,9.901517。请问该暗沙叫什么?
map
609
zh
Find the short clip on a public video platform that satisfies all of the following: - It shows two well-known towers in the same city, and the straight-line direction from the first to the second trends roughly toward the northeast. - Its title contains only the two towers’ English nicknames joined by a non-letter symbol (no other Latin-script words), optionally preceded by an icon. - The uploader’s channel is dominated by diary-style personal posts. - The clip itself is only a few tens of seconds long. What is the clip (give the exact title and its URL)?
multidomain
610
en
Identify a European telecommunications equipment provider that meets the following criteria: 1. Headquartered in Sweden with market capitalization between $15B and $25B as of August 15, 2025. 2. Reported Q2 2025 revenue exceeding $5.6 billion USD, but net income declining by over 40% compared to Q1 2025. 3. Underperformed the iShares Global Tech ETF (IXN) with a YTD stock price return below -5% as of August 10, 2025. 4. Maintained a debt-to-equity ratio above 60% in its latest quarterly balance sheet (Q2 2025).
finance
611
en
Identify a NASDAQ-listed technology company headquartered in California with the following characteristics: 1. Its Q2 2025 revenue exceeded $100 billion USD. 2. Its year-to-date (YTD) stock price change as of August 20, 2025, was negative (-3% or lower). 3. Its market capitalization on July 31, 2025, was greater than the average market cap of the top 5 S&P 500 components on the same date. What is this company's stock symbol?
finance
612
en
A Phase 1/2 trial is assessing a new monoclonal antibody directed against Interleukin-2 combined with recombinant human IL-2 and immune modulators for metastatic malignancies. Which study meets these criteria? 1. The protocol enrolls individuals with advanced melanoma needing prior failure on dual immune checkpoint blockade (either PD-1/CTLA-4 or PD-1/LAG-3 inhibitors) and non-small cell lung cancer with PD-L1 expression ≥1%. 2. Active study sites as of late 2025 are located in regions with area codes 734/313, 816, 281/713/214, and country code +61. 3. An industry-funded trial comparing anti-PD-L1 therapy in NSCLC patients and anti-PD-1 therapy in melanoma patients. 4. Primary endpoints involve establishing dose-limiting toxicities and Phase 2 dosing through drug exposure monitoring and adverse event assessment. 5. Anticipated primary study conclusion in Q2 2026 using an open-label, dose-escalation approach.
bio
613
en
On YouTube, there is a video that meets all of the following conditions: 1) Uploaded in September 2025; 2) Approximately 13 minutes long; 3) A highly-liked comment states, "Sid making every possible excuse to get Lamine. Classic Sid"; 4) The transcript mentions a player’s rating increasing from 81 to 89 in one season and calls him the "highest rated 18-year-old in FIFA history"; 5) The channel has over 2 million subscribers. Which video is this? Provide its URL.
video
614
en
在 YouTube 上,有一个视频满足以下全部条件: 1) 视频时长约 144 分钟; 2) 上传日期为 2025 年 9 月 5 日; 3) 视频描述中包含连续出现的五个名字 "Crystal, Lily, Megan, Roxy, and Kevin"; 4) 点赞数最高的热门评论包含短语 "brainrot god" 且点赞数超过 10; 5) 所在频道订阅量超过了400k。 请问这是哪一个视频?请给出它的 URL。
video
615
zh
A young infant presents with onset of seizures and neurodevelopmental delay. Whole-exome sequencing reveals a homozygous pathogenic variant in a gene on chromosome 3 that encodes a multi-substrate decarboxylase. Following a trial of oral β-alanine supplementation, plasma β-alanine levels increased markedly, accompanied by the typical adverse reaction of paresthesia (“tingling/pinprick” sensation). Based on the above evidence, the most likely diagnosis is:
bio
616
en
在 YouTube 上,有一个视频满足以下全部条件: 1) 视频时长精确到秒为 2 分 59 秒; 2) 视频包含标题为 "Video" 的章节,且该章节从第 20 秒开始; 3) 有个评论以 "God bless y'all" 开头,且该评论获得超过 400 个点赞; 4) 视频简介中同时出现 "Good Good Production" 和 "#paincureriddim" 两个短语; 请问这是哪一个视频?
video
617
zh
A rare disorder affecting infants presents with generalized skin inflammation, persistent gastrointestinal disturbances, and significant failure to thrive during early infancy. Laboratory findings indicate defective immune recognition of common pathogens, leading to recurrent infections. Genetic testing identifies a pathogenic variant in a terminal complement pathway gene located on chromosome 9. Therapeutic interventions often include transfusions of plasma-derived components. Which condition is being described?
bio
618
en
A 28-year-old male presents with widespread areas of macular atrophy predominantly affecting the upper body and arms. The lesions demonstrate a crinkled texture with palpable outpouchings. Histopathological examination reveals mid-dermal elastolysis confirmed by elastic tissue stains. Serologic tests show absence of antibodies linked to coagulation disorders, including lupus anticoagulant. There is no known hereditary dermatological condition in the family. Which diagnosis best aligns with these findings?
bio
619
en
A pilot clinical trial investigated a novel dissociative steroidal anti-inflammatory drug in male participants aged 18–64 with an X-linked muscular dystrophy characterized by partial dystrophin production. This multicenter, randomized, double-blind, placebo-controlled study assessed safety outcomes including laboratory parameters and vital signs over 24 weeks. Conducted at research sites in the United States and Italy, the trial was sponsored by a rare disease biopharma company collaborating with a European partner, concluding data collection in mid-2025. What is the NCT ID for this study?
bio
620
en