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{ "id": "q_0", "content": "Naloxone [SEP] Naloxone reverses the antihypertensive effect of clonidine.", "tokenized_content": [ 2, 21926, 3, 21926, 28817, 1920, 16439, 2495, 1927, 26596, 18, 3 ] }
[ { "id": "p_0", "content": "Naloxone [SEP] A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid recepto", "score": 1, "type": null, "tokenized_content": [ 2, 21926, 3, 43, 2487, 27059, 81...
{ "id": "q_1", "content": "clonidine [SEP] Naloxone reverses the antihypertensive effect of clonidine.", "tokenized_content": [ 2, 26596, 3, 21926, 28817, 1920, 16439, 2495, 1927, 26596, 18, 3 ] }
[ { "id": "p_1", "content": "Clonidine [SEP] An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonl", "score": 1, "type": null, "tokenized_content": [ 2, 26596, 3, 1925, 20697, 10457, ...
{ "id": "q_2", "content": "hypertensive [SEP] In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by ", "tokenized_content": [ 2, 11706, 3, 1922, 26844, 11682, 20536, 1914, 6756, 16, 12753, 11706, 3615, 1920, 3714, 1922, 2877, 3772, 1930, 4003, 2769, 4152, 2007, 3 ] }
[ { "id": "p_2", "content": "Hypertension [SEP] Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is c", "score": 1, "type": null, "tokenized_content": [ 2, 5579, 3, 23334, 2149, 5510, ...
{ "id": "q_3", "content": "clonidine [SEP] crease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, ", "tokenized_content": [ 2, 26596, 3, 3478, 2051, 1922, 2877, 3772, 1930, 4003, 2769, 4152, 2007, 7307, 26596, 16, 25, 1942, 2036, 13362, 19, 3621, 16, 1982, 5069, 2014, 9432, 2007, 13120, 12852, 2912, 3 ] }
[ { "id": "p_3", "content": "Clonidine [SEP] An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonl", "score": 1, "type": null, "tokenized_content": [ 2, 26596, 3, 1925, 20697, 10457, ...
{ "id": "q_4", "content": "hypotensive [SEP] /kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg. The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reverse", "tokenized_content": [ 2, 12201, 3766, 3, 19, 3621, 16, 1982, 5069, 2014, 9432, 2007, 13120, 12852, 2912, 16, 20, 18, 22, 1942, 22, 2786, 19, 3621, 18, 1920, 12201, 3766, 2495, 1927, 2813, 3 ] }
[ { "id": "p_4", "content": "Hypotension [SEP] Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DI", "score": 1, "type": null, "tokenized_content": [ 2, 16453, 3, 20756, 2330, 2877, ...
{ "id": "q_5", "content": "alpha-methyldopa [SEP] y nalozone, 0.2 to 2 mg/kg. The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone alone did not", "tokenized_content": [ 2, 4595, 17, 4963, 22389, 4302, 3, 67, 13120, 12852, 2912, 16, 20, 18, 22, 1942, 22, 2786, 19, 3621, 18, 1920, 12201, 3766, 2495, 1927, 2813, 2786, 19, 3621, 4595, 3 ] }
[ { "id": "p_5", "content": "Methyldopa [SEP] An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an ant", "score": 1, "type": null, "tokenized_content": [ 2, 4963, 22389, 4302, 3, 1925, ...
{ "id": "q_6", "content": "naloxone [SEP] ct of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone alone did not affect either blood pressure or heart r", "tokenized_content": [ 2, 21926, 3, 3369, 1927, 2813, 2786, 19, 3621, 4595, 17, 4963, 22389, 4302, 1982, 2222, 6426, 9432, 2007, 21926, 18, 21926, 4298, 2811, 2084, 4081, 3108, 2877, 3772, 2014, 4003, 3 ] }
[ { "id": "p_6", "content": "Naloxone [SEP] A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid recepto", "score": 1, "type": null, "tokenized_content": [ 2, 21926, 3, 43, 2487, 27059, 81...
{ "id": "q_7", "content": "Naloxone [SEP] mg/kg alpha-methyldopa was also partially reversed by naloxone. Naloxone alone did not affect either blood pressure or heart rate. In br", "tokenized_content": [ 2, 21926, 3, 2786, 19, 3621, 4595, 17, 4963, 22389, 4302, 1982, 2222, 6426, 9432, 2007, 21926, 18, 21926, 4298, 2811, 2084, 4081, 3108, 2877, 3772, 2014, 4003, 2769, 18, 1922, 3 ] }
[ { "id": "p_7", "content": "Naloxone [SEP] A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid recepto", "score": 1, "type": null, "tokenized_content": [ 2, 21926, 3, 43, 2487, 27059, 81...
{ "id": "q_8", "content": "Lidocaine [SEP] Lidocaine-induced cardiac asystole.", "tokenized_content": [ 2, 19567, 3, 19567, 17, 2719, 4435, 1966, 2298, 2456, 18, 3 ] }
[ { "id": "p_8", "content": "Lidocaine [SEP] A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more pro", "score": 1, "type": null, "tokenized_content": [ 2, 19567, 3, 43, 3076, 16111, 1...
{ "id": "q_9", "content": "cardiac asystole [SEP] Lidocaine-induced cardiac asystole.", "tokenized_content": [ 2, 4435, 1966, 2298, 2456, 3, 19567, 17, 2719, 4435, 1966, 2298, 2456, 18, 3 ] }
[ { "id": "p_9", "content": "Heart Arrest [SEP] Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most c", "score": 1, "type": null, "tokenized_content": [ 2, 4003, 8048, 3, 10975, 1927, ...
{ "id": "q_10", "content": "lidocaine [SEP] Intravenous administration of a single 50-mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the act", "tokenized_content": [ 2, 19567, 3, 7307, 4183, 1927, 43, 2957, 2761, 17, 2786, 14840, 1927, 19567, 1922, 43, 4838, 17, 2476, 17, 4156, 2323, 4306, 1922, 11098, 4621, 1927, 1920, 4033, 3 ] }
[ { "id": "p_10", "content": "Lidocaine [SEP] A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more pro", "score": 1, "type": null, "tokenized_content": [ 2, 19567, 3, 43, 3076, 16111, ...
{ "id": "q_11", "content": "depression [SEP] mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pa", "tokenized_content": [ 2, 4621, 3, 2786, 14840, 1927, 19567, 1922, 43, 4838, 17, 2476, 17, 4156, 2323, 4306, 1922, 11098, 4621, 1927, 1920, 2455, 1927, 1920, 3132, 6952, 17075, 1930, 28355, 13926, 3838, 3 ] }
[ { "id": "p_11", "content": "Depressive Disorder [SEP] An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood distur", "score": 1, "type": null, "tokenized_content": [ 2, 7745, 4770, 3, 1925, 11...
{ "id": "q_12", "content": "bradyarrhythmias [SEP] nditions which might have predisposed him to the development of bradyarrhythmias; and, thus, this probably represented a true idiosyncrasy to li", "tokenized_content": [ 2, 20152, 23246, 15519, 3, 8026, 2092, 1036, 2154, 3284, 2162, 23002, 1007, 13135, 1942, 1920, 2740, 1927, 20152, 23246, 15519, 31, 1930, 16, 2842, 16, 2052, 6226, 5960, 43, 6228, 3 ] }
[ { "id": "p_12", "content": "Bradycardia [SEP] Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. Th", "score": 1, "type": null, "tokenized_content": [ 2, 26192, 3, 4435, 16934, 1988, ...
{ "id": "q_13", "content": "Suxamethonium [SEP] Suxamethonium infusion rate and observed fasciculations. A dose-response stud", "tokenized_content": [ 2, 2020, 11414, 23568, 15414, 3, 2020, 11414, 23568, 15414, 7386, 2769, 1930, 2528, 29990, 18021, 6055, 1036, 18, 43, 3253, 17, 2644, 2060, 3 ] }
[ { "id": "p_13", "content": "Succinylcholine [SEP] A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxan", "score": 1, "type": null, "tokenized_content": [ 2, 13791, 2199, 11603, 3, 43, ...
{ "id": "q_14", "content": "fasciculations [SEP] Suxamethonium infusion rate and observed fasciculations. A dose-response study.", "tokenized_content": [ 2, 29990, 18021, 6055, 1036, 3, 2020, 11414, 23568, 15414, 7386, 2769, 1930, 2528, 29990, 18021, 6055, 1036, 18, 43, 3253, 17, 2644, 2161, 18, 3 ] }
[ { "id": "p_14", "content": "Fasciculation [SEP] Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the for", "score": 1, "type": null, "tokenized_content": [ 2, 29990, 18021, 6055, 3, 28493,...
{ "id": "q_15", "content": "Suxamethonium chloride [SEP] Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.2", "tokenized_content": [ 2, 2020, 11414, 23568, 15414, 9140, 3, 2020, 11414, 23568, 15414, 9140, 12, 2966, 13, 1982, 5254, 51, 18, 64, 18, 1942, 3480, 4160, 5129, 2019, 3798, 3389, 30, 20, 18, 3 ] }
[ { "id": "p_15", "content": "Succinylcholine [SEP] A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxan", "score": 1, "type": null, "tokenized_content": [ 2, 13791, 2199, 11603, 3, 43, ...
{ "id": "q_16", "content": "Sch [SEP] Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg ", "tokenized_content": [ 2, 2966, 3, 2020, 11414, 23568, 15414, 9140, 12, 2966, 13, 1982, 5254, 51, 18, 64, 18, 1942, 3480, 4160, 5129, 2019, 3798, 3389, 30, 20, 18, 2637, 2786, 3 ] }
[ { "id": "p_16", "content": "Succinylcholine [SEP] A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxan", "score": 1, "type": null, "tokenized_content": [ 2, 13791, 2199, 11603, 3, 43, ...
{ "id": "q_17", "content": "tetanic [SEP] was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded.", "tokenized_content": [ 2, 9717, 19510, 3, 1982, 16087, 3108, 2469, 2276, 1982, 2239, 12330, 2644, 1942, 9717, 19510, 4177, 1927, 1920, 24630, 5507, 2014, 2469, 2966, 6103, 2786, 1982, 13862, 18, 3 ] }
[ { "id": "p_17", "content": "Tetany [SEP] A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This cond", "score": 1, "type": null, "tokenized_content": [ 2, 9717, 5323, 3, 43, 4770, 4378,...
{ "id": "q_18", "content": "Fasciculations [SEP] eded. Six additional patients received a 30-mg i.v. bolus dose. Fasciculations in six areas of the body were scored from 0 to 3 and summated a", "tokenized_content": [ 2, 29990, 18021, 6055, 1036, 3, 3347, 1919, 18, 3798, 3281, 2132, 4004, 43, 2627, 17, 2786, 51, 18, 64, 18, 14840, 3253, 18, 29990, 18021, 6055, 1036, 1922, 3798, 3957, 3 ] }
[ { "id": "p_18", "content": "Fasciculation [SEP] Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the for", "score": 1, "type": null, "tokenized_content": [ 2, 29990, 18021, 6055, 3, 28493,...
{ "id": "q_19", "content": "fasciculation [SEP] eas of the body were scored from 0 to 3 and summated as a total fasciculation score. The times to first fasciculation, twitch suppression and", "tokenized_content": [ 2, 29990, 18021, 6055, 3, 4843, 1927, 1920, 3362, 1985, 9032, 2037, 20, 1942, 23, 1930, 4162, 1981, 1966, 43, 2698, 29990, 18021, 6055, 3593, 18, 1920, 3586, 1942, 2561, 29990, 3 ] }
[ { "id": "p_19", "content": "Fasciculation [SEP] Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the for", "score": 1, "type": null, "tokenized_content": [ 2, 29990, 18021, 6055, 3, 28493,...
{ "id": "q_20", "content": "twitch [SEP] a total fasciculation score. The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to t", "tokenized_content": [ 2, 21596, 3, 43, 2698, 29990, 18021, 6055, 3593, 18, 1920, 3586, 1942, 2561, 29990, 18021, 6055, 16, 21596, 6412, 1930, 25608, 6412, 1985, 12442, 2712, 1942, 62, 3 ] }
[ { "id": "p_20", "content": "Tetany [SEP] A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This cond", "score": 1, "type": null, "tokenized_content": [ 2, 9717, 5323, 3, 43, 4770, 4378,...
{ "id": "q_21", "content": "tetanus [SEP] score. The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates. Fasci", "tokenized_content": [ 2, 25608, 3, 3593, 18, 1920, 3586, 1942, 2561, 29990, 18021, 6055, 16, 21596, 6412, 1930, 25608, 6412, 1985, 12442, 2712, 1942, 1920, 7386, 3389, 18, 29990, 3 ] }
[ { "id": "p_21", "content": "Tetany [SEP] A disorder characterized by muscle twitches, cramps, and carpopedal spasm, and when severe, laryngospasm and seizures. This cond", "score": 1, "type": null, "tokenized_content": [ 2, 9717, 5323, 3, 43, 4770, 4378,...
{ "id": "q_22", "content": "Galanthamine hydrobromide [SEP] Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of t", "tokenized_content": [ 2, 5179, 7744, 3812, 3290, 18474, 16408, 1021, 3, 5179, 7744, 3812, 3290, 18474, 16408, 1021, 16, 43, 4872, 8290, 5851, 12074, 21343, 2838, 16, 1922, 1920, 2311, 1927, 62, 3 ] }
[ { "id": "p_22", "content": "Galantamine [SEP] A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor tha", "score": 1, "type": null, "tokenized_content": [ 2, 5179, 23200, 25157, 3, 43, ...
{ "id": "q_23", "content": "scopolamine [SEP] cholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine).", "tokenized_content": [ 2, 25392, 10173, 25157, 3, 15440, 2156, 7124, 4127, 2838, 16, 1922, 1920, 2311, 1927, 1920, 4101, 2564, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 18, 3 ] }
[ { "id": "p_23", "content": "Scopolamine Hydrobromide [SEP] An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics l", "score": 1, "type": null, "tokenized_content": [ 2, 25392, 10173, 25157, 329...
{ "id": "q_24", "content": "Hyoscine [SEP] e drug, in the treatment of the central effects of scopolamine (Hyoscine).", "tokenized_content": [ 2, 4527, 17413, 2912, 3, 47, 2838, 16, 1922, 1920, 2311, 1927, 1920, 4101, 2564, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 18, 3 ] }
[ { "id": "p_24", "content": "Scopolamine Hydrobromide [SEP] An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics l", "score": 1, "type": null, "tokenized_content": [ 2, 25392, 10173, 25157, 329...
{ "id": "q_25", "content": "Galanthamine hydrobromide [SEP] Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-br", "tokenized_content": [ 2, 5179, 7744, 3812, 3290, 18474, 16408, 1021, 3, 5179, 7744, 3812, 3290, 18474, 16408, 1021, 16, 1925, 5851, 12074, 21343, 2838, 7131, 1927, 19879, 1920, 2877, 17, 2387, 3 ] }
[ { "id": "p_25", "content": "Galantamine [SEP] A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor tha", "score": 1, "type": null, "tokenized_content": [ 2, 5179, 23200, 25157, 3, 43, ...
{ "id": "q_26", "content": "scopolamine [SEP] barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine a", "tokenized_content": [ 2, 25392, 10173, 25157, 3, 7104, 16, 1982, 2251, 1922, 43, 2774, 7530, 4101, 2564, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 17612, 5360, 2106, 18, 2176, 1977, 4872, 3 ] }
[ { "id": "p_26", "content": "Scopolamine Hydrobromide [SEP] An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics l", "score": 1, "type": null, "tokenized_content": [ 2, 25392, 10173, 25157, 329...
{ "id": "q_27", "content": "hyoscine [SEP] used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used", "tokenized_content": [ 2, 4527, 17413, 2912, 3, 2251, 1922, 43, 2774, 7530, 4101, 2564, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 17612, 5360, 2106, 18, 2176, 1977, 4872, 8290, 2254, 2861, 3 ] }
[ { "id": "p_27", "content": "Scopolamine Hydrobromide [SEP] An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics l", "score": 1, "type": null, "tokenized_content": [ 2, 25392, 10173, 25157, 329...
{ "id": "q_28", "content": "overdosage [SEP] patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used in anaesthe", "tokenized_content": [ 2, 17612, 5360, 2106, 3, 2774, 7530, 4101, 2564, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 17612, 5360, 2106, 18, 2176, 1977, 4872, 8290, 2254, 2861, 2259, 29043, 2053, 3 ] }
[ { "id": "p_28", "content": "Drug Overdose [SEP] Accidental or deliberate use of a medication or street drug in excess of normal dosage.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 2838, 21090, 3, 24842, 2014, 24921, 13108, 248...
{ "id": "q_29", "content": "physostigmine [SEP] of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neur", "tokenized_content": [ 2, 2861, 2259, 29043, 2053, 3, 1927, 25392, 10173, 25157, 12, 4527, 17413, 2912, 13, 17612, 5360, 2106, 18, 2176, 1977, 4872, 8290, 2254, 2861, 2259, 29043, 2053, 1930, 1977, 2251, 3 ] }
[ { "id": "p_29", "content": "Physostigmine [SEP] A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also c", "score": 1, "type": null, "tokenized_content": [ 2, 2861, 2259, 29043, 2053, 3, ...
{ "id": "q_30", "content": "lithium [SEP] Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats.", "tokenized_content": [ 2, 14330, 3, 2564, 1927, 22712, 2128, 6570, 5653, 1930, 2149, 2213, 6788, 1990, 14330, 17, 2719, 3724, 4604, 4574, 1922, 3615, 18, 3 ] }
[ { "id": "p_30", "content": "Lithium [SEP] An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of", "score": 1, "type": null, "tokenized_content": [ 2, 14330, 3, 1925, 6149, 1922, 1...
{ "id": "q_31", "content": "chronic renal failure [SEP] s of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats.", "tokenized_content": [ 2, 3724, 4604, 4574, 3, 61, 1927, 22712, 2128, 6570, 5653, 1930, 2149, 2213, 6788, 1990, 14330, 17, 2719, 3724, 4604, 4574, 1922, 3615, 18, 3 ] }
[ { "id": "p_31", "content": "Kidney Failure, Chronic [SEP] The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the l", "score": 1, "type": null, "tokenized_content": [ 2, 5245, 4574, 16, 3724, ...
{ "id": "q_32", "content": "lithium [SEP] Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding", "tokenized_content": [ 2, 14330, 3, 3615, 1956, 14330, 17, 2719, 15582, 1985, 6243, 1942, 2149, 2213, 12, 4688, 13, 6788, 3 ] }
[ { "id": "p_32", "content": "Lithium [SEP] An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of", "score": 1, "type": null, "tokenized_content": [ 2, 14330, 3, 1925, 6149, 1922, 1...
{ "id": "q_33", "content": "nephropathy [SEP] Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX", "tokenized_content": [ 2, 15582, 3, 3615, 1956, 14330, 17, 2719, 15582, 1985, 6243, 1942, 2149, 2213, 12, 4688, 13, 6788, 16, 22712, 2128, 6570, 5653, 12, 27578, 3 ] }
[ { "id": "p_33", "content": "Kidney Diseases [SEP] Pathological processes of the KIDNEY or its component tissues.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 5245, 3902, 3, 6598, 4028, 1927, 1920, 5245, 2014, 2496, ...
{ "id": "q_34", "content": "renal failure [SEP] to induce glomerular hyperfiltration and further progression of renal failure. Newborn female Wistar rats were fed a lithium-containing diet ", "tokenized_content": [ 2, 4604, 4574, 3, 1942, 4769, 11655, 4194, 6870, 6003, 1930, 2520, 4380, 1927, 4604, 4574, 18, 12203, 4232, 15668, 3615, 1985, 5788, 43, 14330, 17, 3165, 3986, 3 ] }
[ { "id": "p_34", "content": "Renal Insufficiency [SEP] Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ", "score": 1, "type": null, "tokenized_content": [ 2, 4604, 14566, 3, 2961, 1...
{ "id": "q_35", "content": "Li [SEP] sed a fall in filtration fraction and an increase in fractional Li excretion. Lithium also caused proteinuria and systolic hyperte", "tokenized_content": [ 2, 2336, 3, 6276, 43, 6462, 1922, 10347, 3906, 1930, 1925, 2760, 1922, 14436, 2336, 11093, 18, 14330, 2222, 4189, 15831, 1930, 8541, 4506, 1021, 3 ] }
[ { "id": "p_35", "content": "Lithium [SEP] An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of", "score": 1, "type": null, "tokenized_content": [ 2, 14330, 3, 1925, 6149, 1922, 1...
{ "id": "q_36", "content": "Lithium [SEP] filtration fraction and an increase in fractional Li excretion. Lithium also caused proteinuria and systolic hypertension in absence of", "tokenized_content": [ 2, 14330, 3, 10347, 3906, 1930, 1925, 2760, 1922, 14436, 2336, 11093, 18, 14330, 2222, 4189, 15831, 1930, 8541, 5579, 1922, 3905, 1927, 3 ] }
[ { "id": "p_36", "content": "Lithium [SEP] An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of", "score": 1, "type": null, "tokenized_content": [ 2, 14330, 3, 1925, 6149, 1922, 1...
{ "id": "q_37", "content": "proteinuria [SEP] and an increase in fractional Li excretion. Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis. HP ", "tokenized_content": [ 2, 15831, 3, 1930, 1925, 2760, 1922, 14436, 2336, 11093, 18, 14330, 2222, 4189, 15831, 1930, 8541, 5579, 1922, 3905, 1927, 19268, 25081, 18, 4688, 3 ] }
[ { "id": "p_37", "content": "Proteinuria [SEP] The presence of proteins in the urine, an indicator of KIDNEY DISEASES.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 15831, 3, 1920, 2990, 1927, 2697, 1922, 1920, 6960, ...
{ "id": "q_38", "content": "hypertension [SEP] onal Li excretion. Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis. HP failed to accentuante prog", "tokenized_content": [ 2, 5579, 3, 1990, 1923, 2336, 11093, 18, 14330, 2222, 4189, 15831, 1930, 8541, 5579, 1922, 3905, 1927, 19268, 25081, 18, 4688, 6617, 1942, 26884, 13785, 2057, 1965, 1029, 3 ] }
[ { "id": "p_38", "content": "Hypertension [SEP] Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is c", "score": 1, "type": null, "tokenized_content": [ 2, 5579, 3, 23334, 2149, 5510, ...
{ "id": "q_39", "content": "glomerulosclerosis [SEP] also caused proteinuria and systolic hypertension in absence of glomerulosclerosis. HP failed to accentuante progression of renal failure and in f", "tokenized_content": [ 2, 19268, 25081, 3, 2222, 4189, 15831, 1930, 8541, 5579, 1922, 3905, 1927, 19268, 25081, 18, 4688, 6617, 1942, 26884, 13785, 2057, 4380, 1927, 4604, 4574, 1930, 1922, 48, 3 ] }
[ { "id": "p_39", "content": "Glomerulonephritis [SEP] Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including anti", "score": 1, "type": null, "tokenized_content": [ 2, 27057, 3, 4531, 1927, 19...
{ "id": "q_40", "content": "creatinine [SEP] failure and in fact tended to increase GFR and decrease plasma creatinine levels in lithium pretreated rats. NX caused an additive deteri", "tokenized_content": [ 2, 9374, 3, 4574, 1930, 1922, 2371, 10587, 1942, 2760, 15316, 1930, 3714, 3582, 9374, 2428, 1922, 14330, 12152, 3615, 18, 27578, 4189, 1925, 10359, 10641, 1033, 3 ] }
[ { "id": "p_40", "content": "Creatinine [SEP] ", "score": 1, "type": null, "tokenized_content": [ 2, 9374, 3, 3 ] } ]
{ "id": "q_41", "content": "chronic renal failure [SEP] roteinuria and arterial systolic hypertension. In this model of chronic renal failure the decline in GFR is not accompanied by a corresponding fall i", "tokenized_content": [ 2, 3724, 4604, 4574, 3, 5337, 14818, 8754, 1930, 6624, 8541, 5579, 18, 1922, 2052, 2322, 1927, 3724, 4604, 4574, 1920, 6859, 1922, 15316, 1977, 2084, 7936, 2007, 43, 3980, 6462, 3 ] }
[ { "id": "p_41", "content": "Kidney Failure, Chronic [SEP] The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the l", "score": 1, "type": null, "tokenized_content": [ 2, 5245, 4574, 16, 3724, ...
{ "id": "q_42", "content": "Crohn's disease [SEP] Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive propert", "tokenized_content": [ 2, 17563, 11, 61, 2573, 3, 2311, 1927, 17563, 11, 61, 2573, 1956, 10630, 12546, 2687, 30, 1925, 7267, 1956, 12910, 3405, 1031, 3 ] }
[ { "id": "p_42", "content": "Crohn Disease [SEP] A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM", "score": 1, "type": null, "tokenized_content": [ 2, 17563, 2573, 3, 43, 3724, ...
{ "id": "q_43", "content": "fusidic acid [SEP] Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyc", "tokenized_content": [ 2, 10630, 12546, 2687, 3, 2311, 1927, 17563, 11, 61, 2573, 1956, 10630, 12546, 2687, 30, 1925, 7267, 1956, 12910, 3879, 2551, 1942, 21309, 3 ] }
[ { "id": "p_43", "content": "Fusidic Acid [SEP] An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting tra", "score": 1, "type": null, "tokenized_content": [ 2, 10630, 12546, 2687, 3, 1925, ...
{ "id": "q_44", "content": "cyclosporin [SEP] cid: an antibiotic with immunosuppressive properties similar to cyclosporin.", "tokenized_content": [ 2, 17640, 1921, 3, 18069, 30, 1925, 7267, 1956, 12910, 3879, 2551, 1942, 17640, 1921, 18, 3 ] }
[ { "id": "p_44", "content": "Cyclosporine [SEP] A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes.", "score": 1, "type": null, "tokenized_content": [ 2, 21002, 3, 43, 9821, 3075, ...
{ "id": "q_45", "content": "cyclosporin [SEP] h T-cell specific immunosuppressive effects similar to those of cyclosporin. Because of the need for the development of new treatments for ", "tokenized_content": [ 2, 17640, 1921, 3, 50, 62, 17, 2024, 2487, 12910, 2564, 2551, 1942, 2690, 1927, 17640, 1921, 18, 2882, 1927, 1920, 2942, 1958, 1920, 2740, 1927, 2814, 4930, 1958, 3 ] }
[ { "id": "p_45", "content": "Cyclosporine [SEP] A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes.", "score": 1, "type": null, "tokenized_content": [ 2, 21002, 3, 43, 9821, 3075, ...
{ "id": "q_46", "content": "Crohn's disease [SEP] . Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics ", "tokenized_content": [ 2, 17563, 11, 61, 2573, 3, 18, 2882, 1927, 1920, 2942, 1958, 1920, 2740, 1927, 2814, 4930, 1958, 17563, 11, 61, 2573, 16, 43, 9404, 2161, 1982, 10466, 1942, 5383, 1920, 3 ] }
[ { "id": "p_46", "content": "Crohn Disease [SEP] A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM", "score": 1, "type": null, "tokenized_content": [ 2, 17563, 2573, 3, 43, 3724, ...
{ "id": "q_47", "content": "fusidic acid [SEP] undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy-resistant patients. Eight ", "tokenized_content": [ 2, 10630, 12546, 2687, 3, 10466, 1942, 5383, 1920, 24358, 1036, 1930, 17934, 1927, 10630, 12546, 2687, 2311, 1922, 3724, 3500, 16, 3181, 17, 4910, 2132, 18, 5066, 3 ] }
[ { "id": "p_47", "content": "Fusidic Acid [SEP] An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting tra", "score": 1, "type": null, "tokenized_content": [ 2, 10630, 12546, 2687, 3, 1925, ...
{ "id": "q_48", "content": "Fusidic acid [SEP] Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects", "tokenized_content": [ 2, 10630, 12546, 2687, 3, 10630, 12546, 2687, 1977, 1925, 7267, 1956, 62, 17, 2024, 2487, 12910, 2564, 3 ] }
[ { "id": "p_48", "content": "Fusidic Acid [SEP] An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting tra", "score": 1, "type": null, "tokenized_content": [ 2, 10630, 12546, 2687, 3, 1925, ...
{ "id": "q_49", "content": "nausea [SEP] cts, but dose reduction was required in two patients because of nausea. Biochemically, an increase in alkaline phosphatases was noted ", "tokenized_content": [ 2, 13759, 3, 15359, 16, 2308, 3253, 3378, 1982, 3414, 1922, 2288, 2132, 2882, 1927, 13759, 18, 25839, 16, 1925, 2760, 1922, 10746, 19131, 1982, 5040, 3 ] }
[ { "id": "p_49", "content": "Nausea [SEP] An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and moti", "score": 1, "type": null, "tokenized_content": [ 2, 13759, 3, 1925, 25429, 15826, ...
{ "id": "q_50", "content": "inflammatory bowel disease [SEP] rationale for the use of fusidic acid at the cytokine level in inflammatory bowel disease, we suggest that the role of this treatment should be further i", "tokenized_content": [ 2, 3769, 9472, 2573, 3, 13202, 1958, 1920, 2485, 1927, 10630, 12546, 2687, 2019, 1920, 6137, 2237, 1922, 3769, 9472, 2573, 16, 2038, 3220, 1988, 1920, 2770, 1927, 2052, 2311, 3066, 3 ] }
[ { "id": "p_50", "content": "Inflammatory Bowel Diseases [SEP] Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes C", "score": 1, "type": null, "tokenized_content": [ 2, 3769, 9472, 3902, 3, ...
{ "id": "q_51", "content": "myocardial injury [SEP] Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers.", "tokenized_content": [ 2, 6497, 4047, 3, 15894, 4158, 3095, 1927, 6497, 4047, 1922, 7652, 2169, 13123, 9045, 7764, 5675, 18, 3 ] }
[ { "id": "p_51", "content": "Cardiomyopathies [SEP] A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classifi", "score": 1, "type": null, "tokenized_content": [ 2, 8291, 16038, 3, 43, 2210, ...
{ "id": "q_52", "content": "cocaine [SEP] c evidence of myocardial injury in psychiatrically hospitalized cocaine abusers.", "tokenized_content": [ 2, 9045, 3, 45, 3095, 1927, 6497, 4047, 1922, 7652, 2169, 13123, 9045, 7764, 5675, 18, 3 ] }
[ { "id": "p_52", "content": "Cocaine [SEP] An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinic", "score": 1, "type": null, "tokenized_content": [ 2, 9045, 3, 1925, 29951, 9603, 5...
{ "id": "q_53", "content": "cocaine [SEP] The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophreni", "tokenized_content": [ 2, 9045, 3, 1920, 22477, 1036, 12, 11497, 13, 1927, 4922, 9045, 17, 2186, 16435, 2132, 1985, 2452, 1956, 1920, 11497, 1036, 1927, 2761, 7603, 1033, 3 ] }
[ { "id": "p_53", "content": "Cocaine [SEP] An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinic", "score": 1, "type": null, "tokenized_content": [ 2, 9045, 3, 1925, 29951, 9603, 5...
{ "id": "q_54", "content": "schizophrenic [SEP] f 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls. Eleven of the cocaine abusers and none of the control", "tokenized_content": [ 2, 28247, 3, 48, 4922, 9045, 17, 2186, 16435, 2132, 1985, 2452, 1956, 1920, 11497, 1036, 1927, 2761, 28247, 3562, 18, 14483, 1927, 1920, 9045, 7764, 5675, 1930, 6046, 1927, 1920, 3 ] }
[ { "id": "p_54", "content": "Schizophrenia [SEP] A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALL", "score": 1, "type": null, "tokenized_content": [ 2, 7899, 3, 43, 4010, 6687, ...
{ "id": "q_55", "content": "myocardial injury [SEP] busers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch b", "tokenized_content": [ 2, 6497, 4047, 3, 11730, 2045, 1930, 6046, 1927, 1920, 3562, 2430, 11497, 3095, 1927, 2228, 6497, 4047, 3608, 1966, 6497, 8358, 16, 7716, 16, 1930, 14142, 6089, 44, 3 ] }
[ { "id": "p_55", "content": "Cardiomyopathies [SEP] A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classifi", "score": 1, "type": null, "tokenized_content": [ 2, 8291, 16038, 3, 43, 2210, ...
{ "id": "q_56", "content": "myocardial infarction [SEP] ls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.", "tokenized_content": [ 2, 6497, 8358, 3, 6639, 2430, 11497, 3095, 1927, 2228, 6497, 4047, 3608, 1966, 6497, 8358, 16, 7716, 16, 1930, 14142, 6089, 3367, 18, 3 ] }
[ { "id": "p_56", "content": "Myocardial Infarction [SEP] NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).\n ", "score": 1, "type": null, "tokenized_content": [ 2, 6497, 8358, 3, 7476, 1927, 19...
{ "id": "q_57", "content": "ischemia [SEP] significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.", "tokenized_content": [ 2, 7716, 3, 2228, 6497, 4047, 3608, 1966, 6497, 8358, 16, 7716, 16, 1930, 14142, 6089, 3367, 18, 3 ] }
[ { "id": "p_57", "content": "Ischemia [SEP] A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS,", "score": 1, "type": null, "tokenized_content": [ 2, 7716, 3, 43, 26497, 1915, 90...
{ "id": "q_58", "content": "bundle branch block [SEP] ocardial injury defined as myocardial infarction, ischemia, and bundle branch block.", "tokenized_content": [ 2, 14142, 6089, 3367, 3, 5084, 15152, 4047, 3608, 1966, 6497, 8358, 16, 7716, 16, 1930, 14142, 6089, 3367, 18, 3 ] }
[ { "id": "p_58", "content": "Bundle-Branch Block [SEP] A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BU", "score": 1, "type": null, "tokenized_content": [ 2, 14142, 17, 6089, 3367, ...
{ "id": "q_59", "content": "Sulpiride [SEP] Sulpiride-induced tardive dystonia.", "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 23357, 18, 3 ] }
[ { "id": "p_59", "content": "Sulpiride [SEP] A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.", "score": 1, "type": null, "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, ...
{ "id": "q_60", "content": "tardive dystonia [SEP] Sulpiride-induced tardive dystonia.", "tokenized_content": [ 2, 14517, 7408, 1961, 23357, 3, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 23357, 18, 3 ] }
[ { "id": "p_60", "content": "Dystonia [SEP] An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often aff", "score": 1, "type": null, "tokenized_content": [ 2, 23357, 3, 1925, 14204, 2014, ...
{ "id": "q_61", "content": "Sulpiride [SEP] Sulpiride is a selective D2-receptor antagonist with antipsychotic and an", "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, 9596, 10984, 20332, 1021, 1977, 43, 5328, 8631, 17, 3148, 8151, 1956, 17581, 1930, 1925, 3 ] }
[ { "id": "p_61", "content": "Sulpiride [SEP] A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.", "score": 1, "type": null, "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, ...
{ "id": "q_62", "content": "antidepressant [SEP] de is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyram", "tokenized_content": [ 2, 14183, 3, 2028, 1977, 43, 5328, 8631, 17, 3148, 8151, 1956, 17581, 1930, 14183, 3879, 18, 2876, 6370, 6212, 1942, 1998, 3294, 1927, 21346, 3553, 1976, 3 ] }
[ { "id": "p_62", "content": "Antidepressive Agents [SEP] Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE ", "score": 1, "type": null, "tokenized_content": [ 2, 11248, 2320, 4820, 3, ...
{ "id": "q_63", "content": "sulpiride [SEP] gh initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported ", "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, 6101, 6370, 6212, 1942, 1998, 3294, 1927, 21346, 3553, 25238, 1923, 4159, 2564, 16, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 3890, 26682, 3 ] }
[ { "id": "p_63", "content": "Sulpiride [SEP] A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.", "score": 1, "type": null, "tokenized_content": [ 2, 9596, 10984, 20332, 1021, 3, ...
{ "id": "q_64", "content": "tardive dyskinesia [SEP] ht to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a ", "tokenized_content": [ 2, 14517, 7408, 1961, 3890, 26682, 3, 5334, 1942, 1998, 3294, 1927, 21346, 3553, 25238, 1923, 4159, 2564, 16, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 3890, 26682, 1930, 3 ] }
[ { "id": "p_64", "content": "Dyskinesia, Drug-Induced [SEP] Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or", "score": 1, "type": null, "tokenized_content": [ 2, 3890, 26682, 16, 2838, ...
{ "id": "q_65", "content": "parkinsonism [SEP] yramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man w", "tokenized_content": [ 2, 26214, 3, 13031, 25238, 1923, 4159, 2564, 16, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 3890, 26682, 1930, 26214, 2162, 2252, 2568, 14647, 18, 2038, 3942, 43, 3191, 3 ] }
[ { "id": "p_65", "content": "Parkinson Disease, Secondary [SEP] Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected co", "score": 1, "type": null, "tokenized_content": [ 2, 10124, 2573, 16, 406...
{ "id": "q_66", "content": "dystonia [SEP] We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy. We could not ", "tokenized_content": [ 2, 23357, 3, 2038, 3942, 43, 3191, 17, 2476, 17, 4156, 2323, 2746, 3530, 7733, 16294, 23357, 2651, 22, 3221, 2256, 6801, 9596, 10984, 20332, 1021, 3181, 18, 2038, 2578, 2084, 3 ] }
[ { "id": "p_66", "content": "Dystonia [SEP] An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often aff", "score": 1, "type": null, "tokenized_content": [ 2, 23357, 3, 1925, 14204, 2014, ...
{ "id": "q_67", "content": "tardive dystonia [SEP] py. We could not find any previous reports of sulpiride-induced tardive dystonia.", "tokenized_content": [ 2, 14517, 7408, 1961, 23357, 3, 6085, 18, 2038, 2578, 2084, 5387, 2967, 2555, 4710, 1927, 9596, 10984, 20332, 1021, 17, 2719, 14517, 7408, 1961, 23357, 18, 3 ] }
[ { "id": "p_67", "content": "Dystonia [SEP] An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often aff", "score": 1, "type": null, "tokenized_content": [ 2, 23357, 3, 1925, 14204, 2014, ...
{ "id": "q_68", "content": "auditory toxicity [SEP] Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine.", "tokenized_content": [ 2, 8401, 5532, 3, 10046, 1930, 8401, 5532, 1922, 3243, 13968, 1954, 6756, 2132, 5962, 2270, 2070, 19481, 11414, 25157, 18, 3 ] }
[ { "id": "p_68", "content": "Hearing Disorders [SEP] Conditions that impair the transmission of auditory impulses and information from the level of the ear to the temporal cortices,", "score": 1, "type": null, "tokenized_content": [ 2, 8512, 4414, 3, 2961, 1988...
{ "id": "q_69", "content": "desferrioxamine [SEP] Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine.", "tokenized_content": [ 2, 2270, 2070, 19481, 11414, 25157, 3, 10046, 1930, 8401, 5532, 1922, 3243, 13968, 1954, 6756, 2132, 5962, 2270, 2070, 19481, 11414, 25157, 18, 3 ] }
[ { "id": "p_69", "content": "Deferoxamine [SEP] Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in th", "score": 1, "type": null, "tokenized_content": [ 2, 20519, 2325, 3812, 3, 4613, ...
{ "id": "q_70", "content": "desferrioxamine [SEP] an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitor", "tokenized_content": [ 2, 2270, 2070, 19481, 11414, 25157, 3, 1925, 2654, 17, 2935, 3047, 1927, 2161, 4353, 3243, 13968, 1954, 6756, 2132, 5962, 2270, 2070, 19481, 11414, 25157, 12, 2119, 17, 3040, 2786, 3 ] }
[ { "id": "p_70", "content": "Deferoxamine [SEP] Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in th", "score": 1, "type": null, "tokenized_content": [ 2, 20519, 2325, 3812, 3, 4613, ...
{ "id": "q_71", "content": "auditory toxicity [SEP] l toxicity. 6 patients presented clinical symptoms of visual or auditory toxicity. Moreover, detailed ophthalmologic and audiologic studies discl", "tokenized_content": [ 2, 8401, 5532, 3, 54, 5532, 18, 26, 2132, 3549, 2535, 3601, 1927, 3737, 2014, 8401, 5532, 18, 3950, 16, 5720, 14554, 4467, 1930, 18609, 22284, 1935, 2351, 8973, 3 ] }
[ { "id": "p_71", "content": "Hearing Disorders [SEP] Conditions that impair the transmission of auditory impulses and information from the level of the ear to the temporal cortices,", "score": 1, "type": null, "tokenized_content": [ 2, 8512, 4414, 3, 2961, 1988...
{ "id": "q_72", "content": "Visual toxicity [SEP] tudies disclosed abnormalities in 7 more asymptomatic patients. Visual toxicity was of retinal origin and was characterized by a tritan-type dy", "tokenized_content": [ 2, 3737, 5532, 3, 9037, 7408, 1918, 20485, 6754, 1922, 27, 2253, 9978, 2132, 18, 3737, 5532, 1982, 1927, 6943, 4853, 1930, 1982, 4378, 2007, 43, 5083, 3285, 17, 2601, 6433, 3 ] }
[ { "id": "p_72", "content": "Vision Disorders [SEP] Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peri", "score": 1, "type": null, "tokenized_content": [ 2, 9266, 4414, 3, 3737, 12454...
{ "id": "q_73", "content": "a loss of visual acuity [SEP] ized by a tritan-type dyschromatopsy, sometimes associated with a loss of visual acuity and pigmentary retinal deposits. Auditory toxicity was characte", "tokenized_content": [ 2, 43, 3257, 1927, 3737, 12320, 3, 25455, 1919, 2007, 43, 5083, 3285, 17, 2601, 3890, 2072, 2018, 8286, 9196, 16, 8929, 2458, 1956, 43, 3257, 1927, 3737, 12320, 1930, 12905, 3 ] }
[ { "id": "p_73", "content": "Vision Disorders [SEP] Visual impairments limiting one or more of the basic functions of the eye: visual acuity, dark adaptation, color vision, or peri", "score": 1, "type": null, "tokenized_content": [ 2, 9266, 4414, 3, 3737, 12454...
{ "id": "q_74", "content": "pigmentary retinal deposits [SEP] omatopsy, sometimes associated with a loss of visual acuity and pigmentary retinal deposits. Auditory toxicity was characterized by a mid- to high-frequenc", "tokenized_content": [ 2, 12905, 2141, 6943, 14371, 3, 7254, 8286, 9196, 16, 8929, 2458, 1956, 43, 3257, 1927, 3737, 12320, 1930, 12905, 2141, 6943, 14371, 18, 8401, 5532, 1982, 4378, 2007, 43, 3953, 3 ] }
[ { "id": "p_74", "content": "Retinal Diseases [SEP] ", "score": 1, "type": null, "tokenized_content": [ 2, 6943, 3902, 3, 3 ] } ]
{ "id": "q_75", "content": "Auditory toxicity [SEP] d with a loss of visual acuity and pigmentary retinal deposits. Auditory toxicity was characterized by a mid- to high-frequency neurosensorial he", "tokenized_content": [ 2, 8401, 5532, 3, 46, 1956, 43, 3257, 1927, 3737, 12320, 1930, 12905, 2141, 6943, 14371, 18, 8401, 5532, 1982, 4378, 2007, 43, 3953, 17, 1942, 2149, 17, 3528, 7318, 13433, 3 ] }
[ { "id": "p_75", "content": "Hearing Disorders [SEP] Conditions that impair the transmission of auditory impulses and information from the level of the ear to the temporal cortices,", "score": 1, "type": null, "tokenized_content": [ 2, 8512, 4414, 3, 2961, 1988...
{ "id": "q_76", "content": "neurosensorial hearing loss [SEP] Auditory toxicity was characterized by a mid- to high-frequency neurosensorial hearing loss and the lesion was of the cochlear type. Desferrioxamine withdr", "tokenized_content": [ 2, 7318, 13433, 2086, 8512, 3257, 3, 8401, 5532, 1982, 4378, 2007, 43, 3953, 17, 1942, 2149, 17, 3528, 7318, 13433, 2086, 8512, 3257, 1930, 1920, 5709, 1982, 1927, 1920, 15865, 3 ] }
[ { "id": "p_76", "content": "Hearing Loss, Sensorineural [SEP] Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round ", "score": 1, "type": null, "tokenized_content": [ 2, 8512, 3257, 16, 6443,...
{ "id": "q_77", "content": "Desferrioxamine [SEP] sensorial hearing loss and the lesion was of the cochlear type. Desferrioxamine withdrawal resulted in a complete recovery of visual function i", "tokenized_content": [ 2, 2270, 2070, 19481, 11414, 25157, 3, 6443, 2086, 8512, 3257, 1930, 1920, 5709, 1982, 1927, 1920, 15865, 2601, 18, 2270, 2070, 19481, 11414, 25157, 9594, 4306, 1922, 43, 4080, 5241, 3 ] }
[ { "id": "p_77", "content": "Deferoxamine [SEP] Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in th", "score": 1, "type": null, "tokenized_content": [ 2, 20519, 2325, 3812, 3, 4613, ...
{ "id": "q_78", "content": "hearing loss [SEP] ty was characterized by a mid- to high-frequency neurosensorial hearing loss and the lesion was of the cochlear type. Desferrioxamine withdr", "tokenized_content": [ 2, 8512, 3257, 3, 6227, 1982, 4378, 2007, 43, 3953, 17, 1942, 2149, 17, 3528, 7318, 13433, 2086, 8512, 3257, 1930, 1920, 5709, 1982, 1927, 1920, 15865, 2601, 18, 2270, 2070, 3 ] }
[ { "id": "p_78", "content": "Hearing Loss [SEP] A general term for the complete or partial loss of the ability to hear from one or both ears.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 8512, 3257, 3, 43, 3335, 2576, 1958, 1920...
{ "id": "q_79", "content": "toxicity [SEP] for the first time were monitored for detection of audiovisual toxicity. 6 patients presented clinical symptoms of visual or auditory t", "tokenized_content": [ 2, 5532, 3, 1958, 1920, 2561, 2367, 1985, 7027, 1958, 3805, 1927, 18609, 7400, 2224, 5532, 18, 26, 2132, 3549, 2535, 3601, 1927, 3737, 2014, 8401, 62, 3 ] }
[ { "id": "p_79", "content": "Drug-Related Side Effects and Adverse Reactions [SEP] Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chem", "score": 1, "type": null, "tokenized_content": [ 2, 2838, 17, ...
{ "id": "q_80", "content": "Myasthenia gravis [SEP] Myasthenia gravis presenting as weakness after magnesium administration.", "tokenized_content": [ 2, 3057, 27618, 8572, 12413, 1937, 3, 3057, 27618, 8572, 12413, 1937, 8326, 1966, 12175, 2256, 13148, 4183, 18, 3 ] }
[ { "id": "p_80", "content": "Myasthenia Gravis [SEP] A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed agai", "score": 1, "type": null, "tokenized_content": [ 2, 3057, 27618, 8572, 12413, ...
{ "id": "q_81", "content": "magnesium [SEP] Myasthenia gravis presenting as weakness after magnesium administration.", "tokenized_content": [ 2, 13148, 3, 3057, 27618, 8572, 12413, 1937, 8326, 1966, 12175, 2256, 13148, 4183, 18, 3 ] }
[ { "id": "p_81", "content": "Magnesium [SEP] A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of", "score": 1, "type": null, "tokenized_content": [ 2, 13148, 3, 43, 16790, 6149, ...
{ "id": "q_82", "content": "neuromuscular disease [SEP] We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium ad", "tokenized_content": [ 2, 15829, 2573, 3, 2038, 3942, 43, 2774, 1956, 2239, 3432, 4403, 1927, 15829, 2573, 2746, 7935, 13224, 10264, 13229, 6541, 1935, 2256, 20301, 13148, 2041, 3 ] }
[ { "id": "p_82", "content": "Neuromuscular Diseases [SEP] A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manif", "score": 1, "type": null, "tokenized_content": [ 2, 15829, 3902, 3, 43, ...
{ "id": "q_83", "content": "quadriplegic [SEP] no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia. The", "tokenized_content": [ 2, 10264, 13229, 6541, 1935, 3, 2239, 3432, 4403, 1927, 15829, 2573, 2746, 7935, 13224, 10264, 13229, 6541, 1935, 2256, 20301, 13148, 4183, 1958, 17494, 18, 1920, 3 ] }
[ { "id": "p_83", "content": "Quadriplegia [SEP] Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHER", "score": 1, "type": null, "tokenized_content": [ 2, 10264, 13229, 6541, 2126, 3, ...
{ "id": "q_84", "content": "magnesium [SEP] ular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia. The serum magnesium concentrat", "tokenized_content": [ 2, 13148, 3, 3570, 1933, 2573, 2746, 7935, 13224, 10264, 13229, 6541, 1935, 2256, 20301, 13148, 4183, 1958, 17494, 18, 1920, 3256, 13148, 2587, 1926, 3 ] }
[ { "id": "p_84", "content": "Magnesium [SEP] A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of", "score": 1, "type": null, "tokenized_content": [ 2, 13148, 3, 43, 16790, 6149, ...
{ "id": "q_85", "content": "preeclampsia [SEP] ally quadriplegic after parenteral magnesium administration for preeclampsia. The serum magnesium concentration was 3.0 mEq/L, which is usua", "tokenized_content": [ 2, 17494, 3, 2136, 1012, 10264, 13229, 6541, 1935, 2256, 20301, 13148, 4183, 1958, 17494, 18, 1920, 3256, 13148, 3110, 1982, 23, 18, 20, 25509, 19, 54, 16, 2154, 1977, 2022, 3 ] }
[ { "id": "p_85", "content": "Pre-Eclampsia [SEP] A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or with", "score": 1, "type": null, "tokenized_content": [ 2, 2097, 17, 24938, 3, 43, ...
{ "id": "q_86", "content": "postsynaptic neuromuscular blockade [SEP] icant facilitation at rapid rates or after exercise, suggesting postsynaptic neuromuscular blockade. After her strength returned, repetitive stimulation was normal", "tokenized_content": [ 2, 13090, 15829, 9847, 3, 14784, 4905, 17477, 2019, 4052, 3389, 2014, 2256, 4975, 16, 3783, 13090, 15829, 9847, 18, 2256, 3656, 4568, 10418, 16, 12089, 4177, 1982, 2791, 3 ] }
[ { "id": "p_86", "content": "Neuromuscular Diseases [SEP] A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manif", "score": 1, "type": null, "tokenized_content": [ 2, 15829, 3902, 3, 43, ...
{ "id": "q_87", "content": "acetylcholine [SEP] ut single fiber EMG revealed increased jitter and blocking. Her acetylcholine receptor antibody level was markedly elevated. Although paralys", "tokenized_content": [ 2, 14561, 3, 11112, 2957, 6832, 13952, 3404, 2502, 14280, 3519, 1915, 1930, 7472, 18, 3656, 14561, 3148, 3533, 2237, 1982, 7686, 4664, 18, 2876, 11271, 2012, 3 ] }
[ { "id": "p_87", "content": "Acetylcholine [SEP] A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathe", "score": 1, "type": null, "tokenized_content": [ 2, 14561, 3, 43, 15223, 2435, ...
{ "id": "q_88", "content": "paralysis [SEP] choline receptor antibody level was markedly elevated. Although paralysis after magnesium administration has been described in patients w", "tokenized_content": [ 2, 18973, 3, 15440, 3148, 3533, 2237, 1982, 7686, 4664, 18, 2876, 18973, 2256, 13148, 4183, 2258, 2252, 2910, 1922, 2132, 65, 3 ] }
[ { "id": "p_88", "content": "Paralysis [SEP] A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level", "score": 1, "type": null, "tokenized_content": [ 2, 18973, 3, 43, 3335, 2576, 2...
{ "id": "q_89", "content": "myasthenia gravis [SEP] nesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only ", "tokenized_content": [ 2, 3057, 27618, 8572, 12413, 1937, 3, 12100, 2457, 4183, 2258, 2252, 2910, 1922, 2132, 1956, 3171, 3057, 27618, 8572, 12413, 1937, 16, 2176, 2258, 2084, 3024, 2252, 2568, 1942, 1998, 3 ] }
[ { "id": "p_89", "content": "Myasthenia Gravis [SEP] A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed agai", "score": 1, "type": null, "tokenized_content": [ 2, 3057, 27618, 8572, 12413, ...
{ "id": "q_90", "content": "disorder of neuromuscular transmission [SEP] ffects of magnesium should be suspected of having an underlying disorder of neuromuscular transmission.", "tokenized_content": [ 2, 4770, 1927, 15829, 5303, 3, 10735, 2284, 1927, 13148, 3066, 1998, 9407, 1927, 4537, 1925, 5030, 4770, 1927, 15829, 5303, 18, 3 ] }
[ { "id": "p_90", "content": "Neuromuscular Junction Diseases [SEP] Conditions characterized by impaired transmission of impulses at the NEUROMUSCULAR JUNCTION. This may result from disorders that", "score": 1, "type": null, "tokenized_content": [ 2, 15829, 6910, 3902, ...
{ "id": "q_91", "content": "Chloroacetaldehyde [SEP] Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclo", "tokenized_content": [ 2, 10107, 7681, 8790, 3, 10107, 7681, 8790, 1930, 2496, 5100, 1942, 14984, 4575, 18068, 3349, 3145, 2409, 2311, 1956, 17009, 3 ] }
[ { "id": "p_91", "content": "chloroacetaldehyde [SEP] ", "score": 1, "type": null, "tokenized_content": [ 2, 10107, 7681, 8790, 3, 3 ] } ]
{ "id": "q_92", "content": "cyclophosphamide [SEP] ehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication.", "tokenized_content": [ 2, 17135, 3, 12429, 2584, 1021, 1930, 2496, 5100, 1942, 14984, 4575, 18068, 3349, 3145, 2409, 2311, 1956, 17135, 2014, 2647, 1951, 6016, 16408, 1021, 18, 1925, 3599, 2161, 19, 3662, 3 ] }
[ { "id": "p_92", "content": "Cyclophosphamide [SEP] Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to fo", "score": 1, "type": null, "tokenized_content": [ 2, 17135, 3, 7897, 1927, 1925...
{ "id": "q_93", "content": "ifosfamide [SEP] bution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication.", "tokenized_content": [ 2, 2647, 1951, 6016, 16408, 1021, 3, 2308, 2001, 1942, 14984, 4575, 18068, 3349, 3145, 2409, 2311, 1956, 17135, 2014, 2647, 1951, 6016, 16408, 1021, 18, 1925, 3599, 2161, 19, 3662, 3 ] }
[ { "id": "p_93", "content": "Ifosfamide [SEP] Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 2647, 1951, 6016, 16408, 1021, 3, ...
{ "id": "q_94", "content": "chloroacetaldehyde [SEP] Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatic", "tokenized_content": [ 2, 10107, 7681, 8790, 3, 2454, 1990, 2535, 2230, 16, 4168, 1988, 10107, 7681, 8790, 12, 20951, 13, 1977, 1925, 2715, 9483, 1927, 28905, 12813, 10614, 2053, 5521, 3857, 2002, 3 ] }
[ { "id": "p_94", "content": "chloroacetaldehyde [SEP] ", "score": 1, "type": null, "tokenized_content": [ 2, 10107, 7681, 8790, 3, 3 ] } ]
{ "id": "q_95", "content": "CAA [SEP] Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an", "tokenized_content": [ 2, 20951, 3, 2454, 1990, 2535, 2230, 16, 4168, 1988, 10107, 7681, 8790, 12, 20951, 13, 1977, 1925, 2715, 9483, 1927, 28905, 12813, 10614, 2053, 5521, 3857, 2837, 16, 1925, 3 ] }
[ { "id": "p_95", "content": "chloroacetaldehyde [SEP] ", "score": 1, "type": null, "tokenized_content": [ 2, 10107, 7681, 8790, 3, 3 ] } ]
{ "id": "q_96", "content": "hemorrhagic [SEP] out in order to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administrati", "tokenized_content": [ 2, 16052, 3, 2397, 1922, 3238, 1942, 9970, 1920, 2770, 1927, 20951, 1922, 1920, 2740, 1927, 16052, 9446, 3678, 18, 1920, 2230, 4504, 1988, 20951, 2256, 51, 18, 64, 18, 10473, 3 ] }
[ { "id": "p_96", "content": "Hemorrhage [SEP] Bleeding or escape of blood from a vessel.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 10489, 3, 7633, 2014, 11781, 1927, 2877, 2037, 43, 8072, 18, 3 ] ...
{ "id": "q_97", "content": "cystitis [SEP] to elucidate the role of CAA in the development of hemorrhagic cystitis. The data demonstrate that CAA after i.v. administration does n", "tokenized_content": [ 2, 9446, 3678, 3, 1942, 9970, 1920, 2770, 1927, 20951, 1922, 1920, 2740, 1927, 16052, 9446, 3678, 18, 1920, 2230, 4504, 1988, 20951, 2256, 51, 18, 64, 18, 4183, 3731, 56, 3 ] }
[ { "id": "p_97", "content": "Cystitis [SEP] Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful ", "score": 1, "type": null, "tokenized_content": [ 2, 9446, 3678, 3, 4531, 1927, 1...
{ "id": "q_98", "content": "bladder damage [SEP] trate that CAA after i.v. administration does not contribute to bladder damage. When instilled directly into the bladder, CAA exerts urotoxic ", "tokenized_content": [ 2, 7821, 4293, 3, 3390, 2057, 1988, 20951, 2256, 51, 18, 64, 18, 4183, 3731, 2084, 4672, 1942, 7821, 4293, 18, 2469, 4766, 6297, 4103, 2460, 1920, 7821, 16, 20951, 14235, 3 ] }
[ { "id": "p_98", "content": "Urinary Bladder Diseases [SEP] Pathological processes of the URINARY BLADDER.\n ", "score": 1, "type": null, "tokenized_content": [ 2, 7075, 7821, 3902, 3, 6598, 4028, 1927, 1920, 7075, 7821, 1...
{ "id": "q_99", "content": "mesna [SEP] xic effects, it is, however, susceptible to detoxification with mesna.", "tokenized_content": [ 2, 4438, 2175, 3, 11551, 1030, 2564, 16, 2176, 1977, 16, 2406, 16, 7819, 1942, 18169, 1956, 4438, 2175, 18, 3 ] }
[ { "id": "p_99", "content": "Mesna [SEP] A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFA", "score": 1, "type": null, "tokenized_content": [ 2, 4438, 2175, 3, 43, 30011, 2199,...
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