Datasets:
donb-hf
/
secondary-screen-dose-response-curve-parameters

Dataset card Data Studio Files
xet
Community
1
broad_id
string
depmap_id
string
ccle_name
string
screen_id
string
upper_limit
int64
lower_limit
float64
slope
float64
r2
float64
auc
float64
ec50
float64
ic50
float64
name
string
moa
string
target
string
disease.area
string
indication
string
smiles
string
phase
string
passed_str_profiling
bool
row_name
string
BRD-K71847383-001-12-5
ACH-000996
HEC251_ENDOMETRIUM
HTS002
1
1.66413
-0.179775
-0.059451
1.142037
0.000038
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000996
BRD-K71847383-001-12-5
ACH-000622
KNS42_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.388223
-0.147598
0.015874
1.182435
0.033369
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000622
BRD-K71847383-001-12-5
ACH-000403
NCIH747_LARGE_INTESTINE
HTS002
1
1.341018
0.245988
-0.203967
1.230065
0.002902
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000403
BRD-K71847383-001-12-5
ACH-000141
SNU308_BILIARY_TRACT
HTS002
1
2.19792
-0.246082
0.110336
1.314495
0.000752
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000141
BRD-K71847383-001-12-5
ACH-000988
MFE319_ENDOMETRIUM
HTS002
1
1.417748
-0.75312
0.141324
1.094296
0.004129
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000988
BRD-K71847383-001-12-5
ACH-000848
JHH7_LIVER
HTS002
1
1.608422
-0.290429
0.135529
1.327401
0.143795
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000848
BRD-K71847383-001-12-5
ACH-000785
NCIH2126_LUNG
HTS002
1
1.858508
-0.622198
0.131908
1.32144
0.020083
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000785
BRD-K71847383-001-12-5
ACH-000544
OE21_OESOPHAGUS
HTS002
1
1.524409
1.061857
0.004385
1.449052
0.001931
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000544
BRD-K71847383-001-12-5
ACH-000982
GP2D_LARGE_INTESTINE
HTS002
1
2.067322
-0.454984
-0.056182
1.278291
0.00362
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000982
BRD-K71847383-001-12-5
ACH-000021
NCIH1693_LUNG
HTS002
1
1.09997
-0.088182
-0.026476
1.059635
7.037291
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000021
BRD-K71847383-001-12-5
ACH-000823
KYSE140_OESOPHAGUS
HTS002
1
1.45618
-0.290212
-0.062462
1.138347
0.002887
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000823
BRD-K71847383-001-12-5
ACH-000984
HEC6_ENDOMETRIUM
HTS002
1
1.630324
0.603439
-0.068629
1.364856
0.033217
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000984
BRD-K71847383-001-12-5
ACH-000579
UACC257_SKIN
HTS002
1
1.890047
-0.091725
0.049193
1.418633
0.020957
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000579
BRD-K71847383-001-12-5
ACH-001306
8305C_THYROID
HTS002
1
1.608385
4.061808
0.12486
1.16195
0.755328
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-001306
BRD-K71847383-001-12-5
ACH-000318
TE10_OESOPHAGUS
HTS002
1
1.919951
-0.048864
-0.010108
1.437761
0.010706
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000318
BRD-K71847383-001-12-5
ACH-000840
HCC366_LUNG
HTS002
1
1.204166
1.16225
-0.100847
1.138097
0.013795
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000840
BRD-K71847383-001-12-5
ACH-000503
BICR16_UPPER_AERODIGESTIVE_TRACT
HTS002
1
9.353365
-2.558364
0.288094
1.069258
0.000343
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000503
BRD-K71847383-001-12-5
ACH-000919
IM95_STOMACH
HTS002
1
2.86146
0.285706
0.024343
1.251864
112.569045
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000919
BRD-K71847383-001-12-5
ACH-000822
SKMEL24_SKIN
HTS002
1
1.705546
-0.267401
0.040914
1.302584
0.023145
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000822
BRD-K71847383-001-12-5
ACH-000292
NCIH841_LUNG
HTS002
1
1.936598
-0.246336
0.138943
1.330773
0.005078
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000292
BRD-K71847383-001-12-5
ACH-000827
WM793_SKIN
HTS002
1
1.34756
-1.350708
0.190575
1.215558
0.25206
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000827
BRD-K71847383-001-12-5
ACH-000411
769P_KIDNEY
HTS002
1
1.355958
-0.809507
0.226213
1.264768
0.990264
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000411
BRD-K71847383-001-12-5
ACH-000139
PANC0327_PANCREAS
HTS002
1
0.924605
0.568325
-0.201794
0.937375
0.001336
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000139
BRD-K71847383-001-12-5
ACH-000569
ISTMES1_PLEURA
HTS002
1
2.089649
-0.487809
0.085823
1.194269
0.001135
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000569
BRD-K71847383-001-12-5
ACH-000278
COV362_OVARY
HTS002
1
1.219204
-0.07241
-0.002248
1.096558
0.002778
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000278
BRD-K71847383-001-12-5
ACH-000425
UACC62_SKIN
HTS002
1
1.661403
0.081608
-0.022341
1.310153
0.366081
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000425
BRD-K71847383-001-12-5
ACH-000013
ONCODG1_OVARY
HTS002
1
2.305866
0.110774
-0.160194
1.401125
142.577303
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000013
BRD-K71847383-001-12-5
ACH-000730
SKMEL5_SKIN
HTS002
1
1.513883
0.077037
-0.02417
1.33272
0.000027
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000730
BRD-K71847383-001-12-5
ACH-000500
SNU46_UPPER_AERODIGESTIVE_TRACT
HTS002
1
1.849929
-0.417057
0.010547
1.122608
0.000378
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000500
BRD-K71847383-001-12-5
ACH-000222
ASPC1_PANCREAS
HTS002
1
1.128642
0.483312
-0.098323
1.077165
0.023894
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000222
BRD-K71847383-001-12-5
ACH-000477
MALME3M_SKIN
HTS002
1
1.74188
-0.159639
0.071407
1.272825
0.002225
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000477
BRD-K71847383-001-12-5
ACH-000223
HCC1937_BREAST
HTS002
1
1.20395
0.345411
-0.128653
1.156517
0.001242
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000223
BRD-K71847383-001-12-5
ACH-000495
TUHR4TKB_KIDNEY
HTS002
1
1.418975
0.158799
-0.043352
1.287589
0.000447
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000495
BRD-K71847383-001-12-5
ACH-000434
NCIH1915_LUNG
HTS002
1
1.628387
-0.45208
0.2583
1.160206
0.00329
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000434
BRD-K71847383-001-12-5
ACH-000744
NCIH1623_LUNG
HTS002
1
1.143532
-0.089125
-0.093594
1.079561
0.937549
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000744
BRD-K71847383-001-12-5
ACH-000107
CAPAN2_PANCREAS
HTS002
1
1.710207
-0.043703
0.015375
1.327933
0.002309
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000107
BRD-K71847383-001-12-5
ACH-000516
CAL78_BONE
HTS002
1
1.516738
-0.430137
-0.010011
1.151969
0.005363
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000516
BRD-K71847383-001-12-5
ACH-000182
SNU869_BILIARY_TRACT
HTS002
1
1.944138
-0.444945
0.150753
1.24563
0.003459
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000182
BRD-K71847383-001-12-5
ACH-000898
SNU719_STOMACH
HTS002
1
1.961284
-0.576289
0.060378
1.220208
0.003281
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000898
BRD-K71847383-001-12-5
ACH-000040
U118MG_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.673846
-0.163182
-0.044388
1.403579
1.033555
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000040
BRD-K71847383-001-12-5
ACH-000808
HUH28_BILIARY_TRACT
HTS002
1
1.608876
-0.080285
-0.062346
1.276792
0.007857
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000808
BRD-K71847383-001-12-5
ACH-000447
NCIH2228_LUNG
HTS002
1
1.136011
0.009563
-0.111553
1.053976
808,472,476,761,998,500
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000447
BRD-K71847383-001-12-5
ACH-000715
SNU1214_UPPER_AERODIGESTIVE_TRACT
HTS002
1
2.09
-0.179554
-0.024437
1.247867
0.000059
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000715
BRD-K71847383-001-12-5
ACH-000186
NCIH2444_LUNG
HTS002
1
1.477806
-0.900742
-0.041205
1.251487
0.101544
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000186
BRD-K71847383-001-12-5
ACH-000542
HEYA8_OVARY
HTS002
1
1.765968
-0.16546
-0.184065
1.414989
0.226891
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000542
BRD-K71847383-001-12-5
ACH-000943
RKO_LARGE_INTESTINE
HTS002
1
1.151696
0.120367
-0.000016
1.096412
0.000677
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000943
BRD-K71847383-001-12-5
ACH-000174
CAL62_THYROID
HTS002
1
1.496954
-0.679237
0.691334
1.192906
0.024067
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000174
BRD-K71847383-001-12-5
ACH-000393
HLF_LIVER
HTS002
1
2.492667
-0.145572
0.07608
1.61281
0.005884
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000393
BRD-K71847383-001-12-5
ACH-000018
T24_URINARY_TRACT
HTS002
1
1.831768
-0.263074
0.049117
1.295094
0.00601
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000018
BRD-K71847383-001-12-5
ACH-000906
ES2_OVARY
HTS002
1
1.487635
-0.743258
-0.338532
1.281069
0.171282
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000906
BRD-K71847383-001-12-5
ACH-000784
KYSE70_OESOPHAGUS
HTS002
1
3.468248
-0.454166
0.015226
1.315094
0.000345
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000784
BRD-K71847383-001-12-5
ACH-000265
KP4_PANCREAS
HTS002
1
2.115068
-0.0738
-0.037106
1.548068
0.04907
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000265
BRD-K71847383-001-12-5
ACH-000880
AGS_STOMACH
HTS002
1
1.323669
0.079653
-0.01807
1.168073
0.029309
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000880
BRD-K71847383-001-12-5
ACH-000961
ISHIKAWAHERAKLIO02ER_ENDOMETRIUM
HTS002
1
1.635233
-4.698613
0.805178
1.229801
0.020426
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000961
BRD-K71847383-001-12-5
ACH-000847
HGC27_STOMACH
HTS002
1
1.107848
-0.078207
-0.303913
1.060393
1.768253
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000847
BRD-K71847383-001-12-5
ACH-000896
647V_URINARY_TRACT
HTS002
1
1.424256
0.073293
-0.012503
1.234028
0.004488
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000896
BRD-K71847383-001-12-5
ACH-000685
L33_PANCREAS
HTS002
1
1.602589
-2.121454
0.087234
1.500916
1.974056
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000685
BRD-K71847383-001-12-5
ACH-000376
SF295_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.179642
-0.133328
-0.27156
1.130573
152.421845
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000376
BRD-K71847383-001-12-5
ACH-000428
UO31_KIDNEY
HTS002
1
2.200919
-0.771553
-0.108107
1.025789
0.000064
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000428
BRD-K71847383-001-12-5
ACH-000749
DMS273_LUNG
HTS002
1
2.024865
0.082546
-0.082323
1.617646
0.00047
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000749
BRD-K71847383-001-12-5
ACH-000572
G361_SKIN
HTS002
1
1.968091
-0.417417
0.239501
1.292916
0.005791
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000572
BRD-K71847383-001-12-5
ACH-000457
CAL54_KIDNEY
HTS002
1
1.123728
0.058488
-0.00677
1.060945
0.130323
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000457
BRD-K71847383-001-12-5
ACH-000601
MIAPACA2_PANCREAS
HTS002
1
1.580652
-0.028907
0.035399
1.284154
0.0179
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000601
BRD-K71847383-001-12-5
ACH-000651
SW620_LARGE_INTESTINE
HTS002
1
1.527829
-0.540686
0.185064
1.273207
0.095193
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000651
BRD-K71847383-001-12-5
ACH-000361
SKHEP1_LIVER
HTS002
1
1.409461
-0.183088
0.108342
1.21608
0.14898
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000361
BRD-K71847383-001-12-5
ACH-000842
SW480_LARGE_INTESTINE
HTS002
1
1.594244
-0.359648
0.162307
1.172461
0.003713
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000842
BRD-K71847383-001-12-5
ACH-000570
YKG1_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.17355
0.061479
-0.154803
1.550919
0.580217
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000570
BRD-K71847383-001-12-5
ACH-000396
J82_URINARY_TRACT
HTS002
1
1.167856
0.144567
-0.076571
1.069891
0.887262
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000396
BRD-K71847383-001-12-5
ACH-000777
KYSE30_OESOPHAGUS
HTS002
1
1.780203
-0.35144
0.260077
1.278052
0.009969
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000777
BRD-K71847383-001-12-5
ACH-000096
G401_SOFT_TISSUE
HTS002
1
1.648856
-0.377861
0.112391
1.217019
0.007959
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000096
BRD-K71847383-001-12-5
ACH-000955
SNU407_LARGE_INTESTINE
HTS002
1
2.549763
-0.348491
0.189183
1.797917
0.096331
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000955
BRD-K71847383-001-12-5
ACH-000940
AN3CA_ENDOMETRIUM
HTS002
1
1.454095
0.02148
-0.019772
1.245016
0.000048
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000940
BRD-K71847383-001-12-5
ACH-001318
PLCPRF5_LIVER
HTS002
1
1.623403
-0.097543
0.017441
1.298966
0.033265
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-001318
BRD-K71847383-001-12-5
ACH-000332
YAPC_PANCREAS
HTS002
1
1.444793
0.198488
-0.022957
1.211098
0.135587
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000332
BRD-K71847383-001-12-5
ACH-000839
SCABER_URINARY_TRACT
HTS002
1
1.634617
-0.622596
-0.064978
1.122958
0.002231
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000839
BRD-K71847383-001-12-5
ACH-000178
HS766T_PANCREAS
HTS002
1
2.117962
0.138319
0.041361
1.549771
0.100026
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000178
BRD-K71847383-001-12-5
ACH-000421
SW837_LARGE_INTESTINE
HTS002
1
2.723479
0.255413
-0.143096
1.225303
265.340885
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000421
BRD-K71847383-001-12-5
ACH-000524
KURAMOCHI_OVARY
HTS002
1
2.257968
-0.397461
0.144219
1.489548
0.018151
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000524
BRD-K71847383-001-12-5
ACH-000153
NCIH2052_PLEURA
HTS002
1
1.417734
0.121546
-0.043331
1.26227
0.000937
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000153
BRD-K71847383-001-12-5
ACH-000805
COLO679_SKIN
HTS002
1
1.993288
-0.07495
-0.125977
1.471299
0.019695
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000805
BRD-K71847383-001-12-5
ACH-000429
A704_KIDNEY
HTS002
1
0.975675
0.11513
-0.215958
0.983198
0.000061
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000429
BRD-K71847383-001-12-5
ACH-000108
KP3_PANCREAS
HTS002
1
1.266956
-3.329742
0.183945
1.177258
0.383661
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000108
BRD-K71847383-001-12-5
ACH-000939
SKUT1_SOFT_TISSUE
HTS002
1
1.548814
-0.201182
0.107034
1.323542
0.542851
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000939
BRD-K71847383-001-12-5
ACH-000323
42MGBA_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.655581
-0.20409
0.055456
1.233443
0.003418
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000323
BRD-K71847383-001-12-5
ACH-000219
A375_SKIN
HTS002
1
1.461794
-0.303079
0.310451
1.221613
0.057206
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000219
BRD-K71847383-001-12-5
ACH-000054
HT1080_SOFT_TISSUE
HTS002
1
1.128936
-0.112964
-0.02667
1.073308
0.955028
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000054
BRD-K71847383-001-12-5
ACH-000302
SNU1077_ENDOMETRIUM
HTS002
1
3.514349
-0.247353
-0.000334
1.372369
0.000034
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000302
BRD-K71847383-001-12-5
ACH-000324
JHOC5_OVARY
HTS002
1
1.39086
-1.632562
0.21977
1.308182
1.312257
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000324
BRD-K71847383-001-12-5
ACH-000164
PANC1_PANCREAS
HTS002
1
1.314857
-0.026872
-0.037701
1.143519
0.000106
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000164
BRD-K71847383-001-12-5
ACH-000549
SNU1076_UPPER_AERODIGESTIVE_TRACT
HTS002
1
1.763049
-0.218239
0.042705
1.289129
0.006623
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000549
BRD-K71847383-001-12-5
ACH-000650
IGR37_SKIN
HTS002
1
1.718212
-0.221926
-0.329949
1.321186
0.027465
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000650
BRD-K71847383-001-12-5
ACH-000217
JHH6_LIVER
HTS002
1
2.099282
-0.154255
-0.028402
1.362635
0.000644
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000217
BRD-K71847383-001-12-5
ACH-000463
NCIH460_LUNG
HTS002
1
1.398672
0.014835
-0.058375
1.20806
0.000213
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000463
BRD-K71847383-001-12-5
ACH-000748
SJSA1_BONE
HTS002
1
1.472746
-0.033403
0.000362
1.223345
0.002851
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000748
BRD-K71847383-001-12-5
ACH-000788
A2058_SKIN
HTS002
1
1.257768
0.083951
-0.082503
1.139931
0.009808
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000788
BRD-K71847383-001-12-5
ACH-000545
VMCUB1_URINARY_TRACT
HTS002
1
1.230556
-0.330321
-0.069765
1.155792
1.114415
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000545
BRD-K71847383-001-12-5
ACH-000762
YD38_UPPER_AERODIGESTIVE_TRACT
HTS002
1
1.793875
-0.086831
-0.070986
1.394286
0.06683
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000762
BRD-K71847383-001-12-5
ACH-000792
BFTC909_KIDNEY
HTS002
1
3.423108
-0.328087
0.188778
1.488262
0.000567
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000792
BRD-K71847383-001-12-5
ACH-000211
DAOY_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.524189
0.210277
-0.019123
1.289017
128.817277
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000211
BRD-K71847383-001-12-5
ACH-000936
EFO27_OVARY
HTS002
1
1.547973
0.110772
-0.013901
1.395708
0.000012
null
cytarabine
ribonucleotide reductase inhibitor
POLA1, POLB, POLD1, POLE
hematologic malignancy
acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL)
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1, Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
Launched
true
ACH-000936