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Task: Please carry out the NER task for the the text below. Text: For example, although aspirin is a generally well-tolerated pain reliever and is increasingly advocated as a preventative tool for heart attacks and colorectal cancer (Vainio and Miller 2003; Werner et al. 2004), it is also linked to increased risk of gastrointestinal bleeding, cerebral hemorrhage (Werner et al. 2004), and asthma attacks (Jenkins et al. 2004).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: heart,133,138,Anatomy colorectal cancer,151,168,Anatomy gastrointestinal,255,271,Anatomy cerebral,282,290,Anatomy
Task: Please carry out the NER task for the the text below. Text: For example, although aspirin is a generally well-tolerated pain reliever and is increasingly advocated as a preventative tool for heart attacks and colorectal cancer (Vainio and Miller 2003; Werner et al. 2004), it is also linked to increased risk of gastrointestinal bleeding, cerebral hemorrhage (Werner et al. 2004), and asthma attacks (Jenkins et al. 2004).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: heart,133,138,Anatomy colorectal cancer,151,168,Anatomy gastrointestinal,255,271,Anatomy cerebral,282,290,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Human use of DES was banned in the United States in 1971 after the discovery of high rates of rare, clear-cell adenocarcinomas of the vagina and cervix in DES-exposed daughters (Herbst 1981), and later studies showed elevated breast cancer risk in women who took DES during pregnancy (Titus-Ernstoff et al. 2001).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: adenocarcinomas,113,128,Anatomy vagina,136,142,Anatomy cervix,147,153,Anatomy breast cancer,231,244,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Human use of DES was banned in the United States in 1971 after the discovery of high rates of rare, clear-cell adenocarcinomas of the vagina and cervix in DES-exposed daughters (Herbst 1981), and later studies showed elevated breast cancer risk in women who took DES during pregnancy (Titus-Ernstoff et al. 2001).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: adenocarcinomas,113,128,Anatomy vagina,136,142,Anatomy cervix,147,153,Anatomy breast cancer,231,244,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Tumor like Astrocytoma, Temporal lobe epilepsy, raised intra cranial tension, drug induced (tricyclics, Propronolol etc;), meningitis and psychotic illness were shown to cause palinacousis and musical hallucinations [ 2, 3].. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Tumor,0,5,Anatomy Astrocytoma,11,22,Anatomy Temporal lobe,24,37,Anatomy cranial,61,68,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Tumor like Astrocytoma, Temporal lobe epilepsy, raised intra cranial tension, drug induced (tricyclics, Propronolol etc;), meningitis and psychotic illness were shown to cause palinacousis and musical hallucinations [ 2, 3].. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Tumor,0,5,Anatomy Astrocytoma,11,22,Anatomy Temporal lobe,24,37,Anatomy cranial,61,68,Anatomy
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Task: Please carry out the NER task for the the text below. Text: In November 2001 he developed cutaneous purple elevated lesions in his lower limbs that were diagnosed as KS by skin biopsy.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cutaneous purple elevated lesions,30,63,Anatomy lower limbs,71,82,Anatomy KS,106,108,Anatomy skin,112,116,Anatomy
Task: Please carry out the NER task for the the text below. Text: In November 2001 he developed cutaneous purple elevated lesions in his lower limbs that were diagnosed as KS by skin biopsy.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cutaneous purple elevated lesions,30,63,Anatomy lower limbs,71,82,Anatomy KS,106,108,Anatomy skin,112,116,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Two previous studies have shown that both resting and activated NK cells partially kill autologous DCs, as measured by 3-4-h chromium release assays using high NK/DC ratios (11, 12).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cells,64,72,Anatomy DCs,99,102,Anatomy NK,164,166,Anatomy DC,169,171,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Two previous studies have shown that both resting and activated NK cells partially kill autologous DCs, as measured by 3-4-h chromium release assays using high NK/DC ratios (11, 12).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cells,64,72,Anatomy DCs,99,102,Anatomy NK,164,166,Anatomy DC,169,171,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Culturing activated NK cells with DCs at low NK/DC ratios (1: 5) led to increases in TNF-alpha production, which were augmented dramatically by the addition of suboptimal doses (10 ng/ml) of LPS (Fig. 2 A).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,20,28,Anatomy DCs,34,37,Anatomy NK,45,47,Anatomy DC,50,52,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Culturing activated NK cells with DCs at low NK/DC ratios (1: 5) led to increases in TNF-alpha production, which were augmented dramatically by the addition of suboptimal doses (10 ng/ml) of LPS (Fig. 2 A).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,20,28,Anatomy DCs,34,37,Anatomy NK,45,47,Anatomy DC,50,52,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Taken together these results indicate that novel mechanisms control cognate interactions between NK cells and DCs and that NK-DC contact has the potential to serve as an important control switch for both amplifying and attenuating innate immune responses in vivo.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,97,105,Anatomy DCs,110,113,Anatomy NK,123,125,Anatomy DC,128,130,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Taken together these results indicate that novel mechanisms control cognate interactions between NK cells and DCs and that NK-DC contact has the potential to serve as an important control switch for both amplifying and attenuating innate immune responses in vivo.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,97,105,Anatomy DCs,110,113,Anatomy NK,123,125,Anatomy DC,128,130,Anatomy
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Task: Please carry out the NER task for the the text below. Text: These striking differences between death and survival of DCs upon encountering NK cells correlate precisely with our previous results on TNF-alpha and IL-12 p40 production where increasing numbers of NK cells in the culture shifts the NK effect from potent stimulation to complete inhibition (Fig. 2).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: DCs,57,60,Anatomy NK cells,79,87,Anatomy NK cells,204,212,Anatomy NK,239,241,Anatomy
Task: Please carry out the NER task for the the text below. Text: These striking differences between death and survival of DCs upon encountering NK cells correlate precisely with our previous results on TNF-alpha and IL-12 p40 production where increasing numbers of NK cells in the culture shifts the NK effect from potent stimulation to complete inhibition (Fig. 2).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: DCs,57,60,Anatomy NK cells,79,87,Anatomy NK cells,204,212,Anatomy NK,239,241,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Activated/cultured NK cell-mediated death/survival of DCs and NK-DC conjugate formation.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cell,21,28,Anatomy DCs,60,63,Anatomy NK,68,70,Anatomy DC,73,75,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Activated/cultured NK cell-mediated death/survival of DCs and NK-DC conjugate formation.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cell,21,28,Anatomy DCs,60,63,Anatomy NK,68,70,Anatomy DC,73,75,Anatomy
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Task: Please carry out the NER task for the the text below. Text: NK cells can both efficiently kill and potently stimulate DCs in our model system and each of these opposing effects appear dependent on cell-to-cell contact.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,0,8,Anatomy DCs,58,61,Anatomy cell,137,141,Anatomy cell,149,153,Anatomy
Task: Please carry out the NER task for the the text below. Text: NK cells can both efficiently kill and potently stimulate DCs in our model system and each of these opposing effects appear dependent on cell-to-cell contact.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK cells,0,8,Anatomy DCs,58,61,Anatomy cell,137,141,Anatomy cell,149,153,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To quantify these apparent cognate interactions we measured the formation of NK-DC conjugates and compared them to conjugates formed by NK cells and tumor targets.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK,77,79,Anatomy DC,82,84,Anatomy NK cells,138,146,Anatomy tumor,151,156,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To quantify these apparent cognate interactions we measured the formation of NK-DC conjugates and compared them to conjugates formed by NK cells and tumor targets.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: NK,77,79,Anatomy DC,82,84,Anatomy NK cells,138,146,Anatomy tumor,151,156,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Cultured iDCs were incubated for 48 h, alone (A-C), or with NK cells at the following ratios (NK/DC), 1: 5 (D-F), 1: 1 (G-I), and 5: 1 (J-L).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: iDCs,9,13,Anatomy NK cells,63,71,Anatomy NK,98,100,Anatomy DC,103,105,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Cultured iDCs were incubated for 48 h, alone (A-C), or with NK cells at the following ratios (NK/DC), 1: 5 (D-F), 1: 1 (G-I), and 5: 1 (J-L).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: iDCs,9,13,Anatomy NK cells,63,71,Anatomy NK,98,100,Anatomy DC,103,105,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Activated/cultured NK cell-induced DC maturation is dependent on cell-to-cell contact and endogenous TNF-alpha production.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cell,21,28,Anatomy DC,39,41,Anatomy cell,69,73,Anatomy cell,81,85,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Activated/cultured NK cell-induced DC maturation is dependent on cell-to-cell contact and endogenous TNF-alpha production.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK cell,21,28,Anatomy DC,39,41,Anatomy cell,69,73,Anatomy cell,81,85,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Strong similarity between CCN3 and Sonic Hedgehog was observed for the expression pattern in axial structure (notochord and floor plate), in which the left-right asymmetrical pattern in the node area is also conserved (Fig. 1b).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: axial structure,93,108,Anatomy notochord,111,120,Anatomy floor plate,125,136,Anatomy node area,193,202,Anatomy
Task: Please carry out the NER task for the the text below. Text: Strong similarity between CCN3 and Sonic Hedgehog was observed for the expression pattern in axial structure (notochord and floor plate), in which the left-right asymmetrical pattern in the node area is also conserved (Fig. 1b).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: axial structure,93,108,Anatomy notochord,111,120,Anatomy floor plate,125,136,Anatomy node area,193,202,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In chicken embryo, differentiating endothelial cells in the ventral part of blood islands express CCN3 from the initial stage (Fig. 1e).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: embryo,11,17,Anatomy endothelial cells,35,52,Anatomy ventral part,60,72,Anatomy blood islands,76,89,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In chicken embryo, differentiating endothelial cells in the ventral part of blood islands express CCN3 from the initial stage (Fig. 1e).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: embryo,11,17,Anatomy endothelial cells,35,52,Anatomy ventral part,60,72,Anatomy blood islands,76,89,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Individual movement of dorsiflexion, palmar flexion, supination, pronation and radial-ulnar deviation were all significantly better in the dorsiflexed-immobilized group as compared with the palmar flexed immobilized group.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: palmar,37,43,Anatomy radial,79,85,Anatomy ulnar,88,93,Anatomy palmar,194,200,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Individual movement of dorsiflexion, palmar flexion, supination, pronation and radial-ulnar deviation were all significantly better in the dorsiflexed-immobilized group as compared with the palmar flexed immobilized group.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: palmar,37,43,Anatomy radial,79,85,Anatomy ulnar,88,93,Anatomy palmar,194,200,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Histological evaluation was done by a pathologist who was blinded to the experimental groups, and it was based on the intensity of mononuclear and polymorphonuclear infiltrates in the lamina propria, crypt dilation, cellular destruction and mucosal ulceration.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: lamina propria,184,198,Anatomy crypt,200,205,Anatomy cellular,216,224,Anatomy mucosal,241,248,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Histological evaluation was done by a pathologist who was blinded to the experimental groups, and it was based on the intensity of mononuclear and polymorphonuclear infiltrates in the lamina propria, crypt dilation, cellular destruction and mucosal ulceration.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: lamina propria,184,198,Anatomy crypt,200,205,Anatomy cellular,216,224,Anatomy mucosal,241,248,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: In a first experiment, we searched for differences in glomerular ultrastructure and peripheral neurogenesis between WT and STOP null mice: a first group of 24 mice, 3-to 6-month-old, was used for ultrastructural study of the OBs; a second group of 13 animals was used to analyse proliferation and apoptosis in the OE and VNE on paraffin sections in 3-month-old mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: glomerular,54,64,Anatomy OE,320,322,Anatomy VNE,327,330,Anatomy paraffin sections,334,351,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: In a first experiment, we searched for differences in glomerular ultrastructure and peripheral neurogenesis between WT and STOP null mice: a first group of 24 mice, 3-to 6-month-old, was used for ultrastructural study of the OBs; a second group of 13 animals was used to analyse proliferation and apoptosis in the OE and VNE on paraffin sections in 3-month-old mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: glomerular,54,64,Anatomy OE,320,322,Anatomy VNE,327,330,Anatomy paraffin sections,334,351,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Taken together, it seems plausible that motivational reward processes in the caudate enhance preparatory activation in subcortical as well as in cortical nodes of the oculomotor network.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: caudate,77,84,Anatomy subcortical,119,130,Anatomy cortical nodes,145,159,Anatomy oculomotor network,167,185,Anatomy
Task: Please carry out the NER task for the the text below. Text: Taken together, it seems plausible that motivational reward processes in the caudate enhance preparatory activation in subcortical as well as in cortical nodes of the oculomotor network.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: caudate,77,84,Anatomy subcortical,119,130,Anatomy cortical nodes,145,159,Anatomy oculomotor network,167,185,Anatomy
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Task: Please carry out the NER task for the the text below. Text: These results suggest that reward-processing networks and oculomotor-control networks in the brain are connected in such a way (presumably with the dorsal striatum as a common nexus) that reward anticipation can facilitate oculomotor control and alleviate the deficiencies experienced by healthy seniors and PD patients.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: oculomotor - control networks,60,89,Anatomy brain,97,102,Anatomy dorsal striatum,153,168,Anatomy oculomotor,228,238,Anatomy
Task: Please carry out the NER task for the the text below. Text: These results suggest that reward-processing networks and oculomotor-control networks in the brain are connected in such a way (presumably with the dorsal striatum as a common nexus) that reward anticipation can facilitate oculomotor control and alleviate the deficiencies experienced by healthy seniors and PD patients.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: oculomotor - control networks,60,89,Anatomy brain,97,102,Anatomy dorsal striatum,153,168,Anatomy oculomotor,228,238,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Acute treatment with milnacipran results in increased synaptic concentrations of NE but decreased firing of the NE neurons of the locus coeruleus due to increased stimulation of the somatodendritic alpha2-adrenergic autoreceptors.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: synaptic,54,62,Anatomy NE neurons,112,122,Anatomy locus coeruleus,130,145,Anatomy somatodendritic,182,197,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Acute treatment with milnacipran results in increased synaptic concentrations of NE but decreased firing of the NE neurons of the locus coeruleus due to increased stimulation of the somatodendritic alpha2-adrenergic autoreceptors.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: synaptic,54,62,Anatomy NE neurons,112,122,Anatomy locus coeruleus,130,145,Anatomy somatodendritic,182,197,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Jarred foods with vegetables, meats, and desserts may contain added fat from a variety of sources: vegetable oils, cow milk butter, or cream.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: vegetables,18,28,Anatomy meats,30,35,Anatomy vegetable oils,99,113,Anatomy milk,119,123,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Jarred foods with vegetables, meats, and desserts may contain added fat from a variety of sources: vegetable oils, cow milk butter, or cream.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: vegetables,18,28,Anatomy meats,30,35,Anatomy vegetable oils,99,113,Anatomy milk,119,123,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: LPP (OR = 2.36; p < 0.001) was reported to be highly expressed in small intestinal mucosa and may have a structural role at sites of cell adhesion in maintaining cell shape and motility [ 7].. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: small intestinal mucosa,69,92,Anatomy sites,127,132,Anatomy cell,136,140,Anatomy cell,165,169,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: LPP (OR = 2.36; p < 0.001) was reported to be highly expressed in small intestinal mucosa and may have a structural role at sites of cell adhesion in maintaining cell shape and motility [ 7].. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: small intestinal mucosa,69,92,Anatomy sites,127,132,Anatomy cell,136,140,Anatomy cell,165,169,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: It attenuates the signaling activity of G-proteins, blocking the homing of Intra Epithelial Lymphocytes (IELs), and it is specifically expressed both in human small intestinal mucosa and in murine IELs, key players in the development of human CD villous atrophy [ 7], [ 17].. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Intra Epithelial Lymphocytes,77,105,Anatomy IELs,108,112,Anatomy small intestinal mucosa,162,185,Anatomy IELs,200,204,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: It attenuates the signaling activity of G-proteins, blocking the homing of Intra Epithelial Lymphocytes (IELs), and it is specifically expressed both in human small intestinal mucosa and in murine IELs, key players in the development of human CD villous atrophy [ 7], [ 17].. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Intra Epithelial Lymphocytes,77,105,Anatomy IELs,108,112,Anatomy small intestinal mucosa,162,185,Anatomy IELs,200,204,Anatomy
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Task: Please carry out the NER task for the the text below. Text: The results indicate that tumor tissue of RCC liberates VEGF into the systemic blood flow and that s-VEGF is a possible marker for RCC.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tumor tissue,26,38,Anatomy RCC,42,45,Anatomy blood,79,84,Anatomy RCC,133,136,Anatomy
Task: Please carry out the NER task for the the text below. Text: The results indicate that tumor tissue of RCC liberates VEGF into the systemic blood flow and that s-VEGF is a possible marker for RCC.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tumor tissue,26,38,Anatomy RCC,42,45,Anatomy blood,79,84,Anatomy RCC,133,136,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Obstructive nephropathy is one of the most important causes of renal failure in infants and children, while polycystic kidney disease (PKD) is a major cause of renal failure in the adult population.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: renal,63,68,Anatomy polycystic,108,118,Anatomy kidney,119,125,Anatomy renal,161,166,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Obstructive nephropathy is one of the most important causes of renal failure in infants and children, while polycystic kidney disease (PKD) is a major cause of renal failure in the adult population.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: renal,63,68,Anatomy polycystic,108,118,Anatomy kidney,119,125,Anatomy renal,161,166,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell,23,27,Anatomy cell,58,62,Anatomy transitional cell carcinoma,102,129,Anatomy bladder cell line,137,154,Anatomy
Task: Please carry out the NER task for the the text below. Text: Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell,23,27,Anatomy cell,58,62,Anatomy transitional cell carcinoma,102,129,Anatomy bladder cell line,137,154,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Our experimental data confirm previous studies showing the in vitro cell growth inhibition of the transitional cell carcinoma of the bladder cell line HTB9 and further showed the induction of cell cycle arrest at the S/G2-M checkpoints.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,68,72,Anatomy transitional cell carcinoma,98,125,Anatomy bladder cell line HTB9,133,155,Anatomy cell,192,196,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Our experimental data confirm previous studies showing the in vitro cell growth inhibition of the transitional cell carcinoma of the bladder cell line HTB9 and further showed the induction of cell cycle arrest at the S/G2-M checkpoints.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,68,72,Anatomy transitional cell carcinoma,98,125,Anatomy bladder cell line HTB9,133,155,Anatomy cell,192,196,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: After the completion of skin development, angiogenesis, i. e., the growth of new capillaries from pre-existing blood vessels, is held to occur in the skin only under pathologic conditions.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: skin,24,28,Anatomy capillaries,81,92,Anatomy blood vessels,113,126,Anatomy skin,152,156,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: After the completion of skin development, angiogenesis, i. e., the growth of new capillaries from pre-existing blood vessels, is held to occur in the skin only under pathologic conditions.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: skin,24,28,Anatomy capillaries,81,92,Anatomy blood vessels,113,126,Anatomy skin,152,156,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: This study uses quantitative histomorphometry and double-immunohistologic detection techniques for the demarcation of proliferating endothelial cells, to show that synchronized hair follicle cycling in adolescent C57BL/6 mice is associated with substantial angiogenesis, and that inhibiting angiogenesis in vivo by the intraperitoneal application of a fumagillin derivative retards experimentally induced anagen development in these mice.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: endothelial cells,134,151,Anatomy hair follicle,179,192,Anatomy intraperitoneal,323,338,Anatomy anagen,409,415,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: This study uses quantitative histomorphometry and double-immunohistologic detection techniques for the demarcation of proliferating endothelial cells, to show that synchronized hair follicle cycling in adolescent C57BL/6 mice is associated with substantial angiogenesis, and that inhibiting angiogenesis in vivo by the intraperitoneal application of a fumagillin derivative retards experimentally induced anagen development in these mice.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: endothelial cells,134,151,Anatomy hair follicle,179,192,Anatomy intraperitoneal,323,338,Anatomy anagen,409,415,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: The findings suggest that elevated serum levels of S-100beta, IL-6 and IL-10 reflect concurrent liver or bone metastases in melanoma.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: serum,35,40,Anatomy liver,102,107,Anatomy bone metastases,111,126,Anatomy melanoma,130,138,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: The findings suggest that elevated serum levels of S-100beta, IL-6 and IL-10 reflect concurrent liver or bone metastases in melanoma.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: serum,35,40,Anatomy liver,102,107,Anatomy bone metastases,111,126,Anatomy melanoma,130,138,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumor,16,21,Anatomy cell,44,48,Anatomy cell,60,64,Anatomy cells,97,102,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumor,16,21,Anatomy cell,44,48,Anatomy cell,60,64,Anatomy cells,97,102,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In this study, we sought to investigate in more detail the role of caspase-3 in apoptotic processes in cultured cells and in cell-free extracts of breast cancer cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cells,114,119,Anatomy cell,127,131,Anatomy extracts,139,147,Anatomy breast cancer cells,151,170,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In this study, we sought to investigate in more detail the role of caspase-3 in apoptotic processes in cultured cells and in cell-free extracts of breast cancer cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cells,114,119,Anatomy cell,127,131,Anatomy extracts,139,147,Anatomy breast cancer cells,151,170,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: We present evidence that apoptosis of caspase-3-deficient MCF-7 breast cancer cells is defective in response to cisplatin treatment, as determined by chromatin condensation, nuclear fragmentation, DNA fragmentation, and release of cytochrome c from the mitochondria.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: caspase - 3 - deficient MCF - 7 breast cancer cells,38,89,Anatomy chromatin,156,165,Anatomy nuclear,180,187,Anatomy mitochondria,259,271,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: We present evidence that apoptosis of caspase-3-deficient MCF-7 breast cancer cells is defective in response to cisplatin treatment, as determined by chromatin condensation, nuclear fragmentation, DNA fragmentation, and release of cytochrome c from the mitochondria.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: caspase - 3 - deficient MCF - 7 breast cancer cells,38,89,Anatomy chromatin,156,165,Anatomy nuclear,180,187,Anatomy mitochondria,259,271,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Vasodilator-stimulated phosphoprotein (VASP) is highly expressed in vascular endothelial cells, where it has been implicated in cellular reorganization during angiogenesis, as well as in endothelial retraction and changes in vessel permeability.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: vascular endothelial cells,71,97,Anatomy cellular,131,139,Anatomy endothelial,190,201,Anatomy vessel,228,234,Anatomy
Task: Please carry out the NER task for the the text below. Text: Vasodilator-stimulated phosphoprotein (VASP) is highly expressed in vascular endothelial cells, where it has been implicated in cellular reorganization during angiogenesis, as well as in endothelial retraction and changes in vessel permeability.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: vascular endothelial cells,71,97,Anatomy cellular,131,139,Anatomy endothelial,190,201,Anatomy vessel,228,234,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: These data provide a mechanism whereby VASP can influence endothelial migration and organization during capillary formation and modulate vascular permeability via effects on endothelial cell contractility.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endothelial,58,69,Anatomy capillary,104,113,Anatomy vascular,137,145,Anatomy endothelial cell,174,190,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: These data provide a mechanism whereby VASP can influence endothelial migration and organization during capillary formation and modulate vascular permeability via effects on endothelial cell contractility.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endothelial,58,69,Anatomy capillary,104,113,Anatomy vascular,137,145,Anatomy endothelial cell,174,190,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Here we show that IL-12 activates an anti-angiogenic program in Con A-activated mouse spleen cells (activated spc) or human PBMC (activated PBMC).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: spleen cells,92,104,Anatomy spc,117,120,Anatomy PBMC,131,135,Anatomy PBMC,148,152,Anatomy
Task: Please carry out the NER task for the the text below. Text: Here we show that IL-12 activates an anti-angiogenic program in Con A-activated mouse spleen cells (activated spc) or human PBMC (activated PBMC).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: spleen cells,92,104,Anatomy spc,117,120,Anatomy PBMC,131,135,Anatomy PBMC,148,152,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To observe the influence of fungus polysaccharides compounds (FPC) in inducing human liver cancer cell Bel-7402 apoptosis in cell cultivating in vitro, the authors analyzed tumor inhibitive gene P53 expression in Bel-7402 apoptosis by applying double immuno-marker.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: liver cancer cell Bel - 7402,86,114,Anatomy cell,128,132,Anatomy tumor,176,181,Anatomy Bel - 7402,216,226,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To observe the influence of fungus polysaccharides compounds (FPC) in inducing human liver cancer cell Bel-7402 apoptosis in cell cultivating in vitro, the authors analyzed tumor inhibitive gene P53 expression in Bel-7402 apoptosis by applying double immuno-marker.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: liver cancer cell Bel - 7402,86,114,Anatomy cell,128,132,Anatomy tumor,176,181,Anatomy Bel - 7402,216,226,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Here we studied the effects of cell morphology on the migration of bovine aortic ECs by culturing cells on micropatterned strips of collagen matrix (60-, 30-, and 15-microm wide).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,31,35,Anatomy aortic ECs,74,84,Anatomy cells,98,103,Anatomy matrix,141,147,Anatomy
Task: Please carry out the NER task for the the text below. Text: Here we studied the effects of cell morphology on the migration of bovine aortic ECs by culturing cells on micropatterned strips of collagen matrix (60-, 30-, and 15-microm wide).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,31,35,Anatomy aortic ECs,74,84,Anatomy cells,98,103,Anatomy matrix,141,147,Anatomy
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Task: Please carry out the NER task for the the text below. Text: The present study provides direct evidence on the role of cell morphology in EC migration, and will help us to understand the mechanisms of EC migration during angiogenesis and wound healing.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,58,62,Anatomy EC,77,79,Anatomy EC,140,142,Anatomy wound,177,182,Anatomy
Task: Please carry out the NER task for the the text below. Text: The present study provides direct evidence on the role of cell morphology in EC migration, and will help us to understand the mechanisms of EC migration during angiogenesis and wound healing.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,58,62,Anatomy EC,77,79,Anatomy EC,140,142,Anatomy wound,177,182,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: The interval between primary surgery and the appearance of gastric cancer in the remnant stomach was significantly shorter in the RSCM group than in the RSCB group.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: gastric cancer,59,73,Anatomy remnant stomach,81,96,Anatomy RSCM,130,134,Anatomy RSCB,153,157,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: The interval between primary surgery and the appearance of gastric cancer in the remnant stomach was significantly shorter in the RSCM group than in the RSCB group.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: gastric cancer,59,73,Anatomy remnant stomach,81,96,Anatomy RSCM,130,134,Anatomy RSCB,153,157,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Invasion of adjacent organs was more frequent in the RSCM group than in the RSCB group and the Ki-67 labeling index of the tumors was significantly higher in the former group.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: organs,21,27,Anatomy RSCM,53,57,Anatomy RSCB,76,80,Anatomy tumors,125,131,Anatomy
Task: Please carry out the NER task for the the text below. Text: Invasion of adjacent organs was more frequent in the RSCM group than in the RSCB group and the Ki-67 labeling index of the tumors was significantly higher in the former group.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: organs,21,27,Anatomy RSCM,53,57,Anatomy RSCB,76,80,Anatomy tumors,125,131,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: In animal or cell culture studies, the growth and spread of cancer can be slowed by many nutrients, food factors, herbal extracts, and well-tolerated, available drugs that are still rarely used in the clinical management of cancer, in part because they seem unlikely to constitute definitive therapies in themselves.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell culture,13,25,Anatomy cancer,60,66,Anatomy extracts,121,129,Anatomy cancer,226,232,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: In animal or cell culture studies, the growth and spread of cancer can be slowed by many nutrients, food factors, herbal extracts, and well-tolerated, available drugs that are still rarely used in the clinical management of cancer, in part because they seem unlikely to constitute definitive therapies in themselves.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell culture,13,25,Anatomy cancer,60,66,Anatomy extracts,121,129,Anatomy cancer,226,232,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Although he was assumed to have difficult airway due to short neck, macroglossia, and disturbance of neck flexion, tracheal intubation was not difficult.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: airway,42,48,Anatomy neck,62,66,Anatomy neck,101,105,Anatomy tracheal,115,123,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Although he was assumed to have difficult airway due to short neck, macroglossia, and disturbance of neck flexion, tracheal intubation was not difficult.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: airway,42,48,Anatomy neck,62,66,Anatomy neck,101,105,Anatomy tracheal,115,123,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The translocation of most proteins across the endoplasmic reticulum or bacterial inner membrane occurs through an aqueous pore that spans the membrane.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endoplasmic reticulum,46,67,Anatomy inner membrane,81,95,Anatomy aqueous pore,114,126,Anatomy membrane,142,150,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The translocation of most proteins across the endoplasmic reticulum or bacterial inner membrane occurs through an aqueous pore that spans the membrane.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endoplasmic reticulum,46,67,Anatomy inner membrane,81,95,Anatomy aqueous pore,114,126,Anatomy membrane,142,150,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Substrates that are translocated co-translationally across the membrane are directed to the translocation pore via an interaction between the cytosolic signal recognition particle and its membrane-bound receptor.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: membrane,65,73,Anatomy translocation pore,94,112,Anatomy cytosolic,144,153,Anatomy membrane,190,198,Anatomy
Task: Please carry out the NER task for the the text below. Text: Substrates that are translocated co-translationally across the membrane are directed to the translocation pore via an interaction between the cytosolic signal recognition particle and its membrane-bound receptor.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: membrane,65,73,Anatomy translocation pore,94,112,Anatomy cytosolic,144,153,Anatomy membrane,190,198,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Since congenital neutropenia and SDS are inherited forms of bone marrow failure, G-CSF may accelerate the propensity for MDS/AML in the genetically altered stem and progenitor cells, especially in those with G-CSF receptor and ras mutations (82% and 50% of patients who transform, respectively).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: bone marrow,60,71,Anatomy AML,129,132,Anatomy stem,160,164,Anatomy progenitor cells,169,185,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Since congenital neutropenia and SDS are inherited forms of bone marrow failure, G-CSF may accelerate the propensity for MDS/AML in the genetically altered stem and progenitor cells, especially in those with G-CSF receptor and ras mutations (82% and 50% of patients who transform, respectively).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: bone marrow,60,71,Anatomy AML,129,132,Anatomy stem,160,164,Anatomy progenitor cells,169,185,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The elevation of noradrenaline produced by isoproterenol is selective for the pineal because it is not observed in the salivary gland innervated by postganglionic adrenergic fibers from the same origin as pineal nerves.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pineal,78,84,Anatomy salivary gland,119,133,Anatomy postganglionic adrenergic fibers,148,180,Anatomy pineal nerves,205,218,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The elevation of noradrenaline produced by isoproterenol is selective for the pineal because it is not observed in the salivary gland innervated by postganglionic adrenergic fibers from the same origin as pineal nerves.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pineal,78,84,Anatomy salivary gland,119,133,Anatomy postganglionic adrenergic fibers,148,180,Anatomy pineal nerves,205,218,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Since noradrenaline and serotonin are detected in pineal nerve vesicles and may coexist in them, the diminution of intravesicular serotonin, by making more storage sites available, probably determines the selective increase of pineal noradrenaline.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pineal nerve vesicles,50,71,Anatomy intravesicular,115,129,Anatomy sites,164,169,Anatomy pineal,227,233,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Since noradrenaline and serotonin are detected in pineal nerve vesicles and may coexist in them, the diminution of intravesicular serotonin, by making more storage sites available, probably determines the selective increase of pineal noradrenaline.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pineal nerve vesicles,50,71,Anatomy intravesicular,115,129,Anatomy sites,164,169,Anatomy pineal,227,233,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: CONCLUSIONS: Indocyanine green dye-enhanced photocoagulation of CNV feeder vessels, facilitated by use of a device that permits real-time visualization of the choroidal circulation while aiming the treatment laser beam, appears to minimize the amount of energy applied to the fundus and the volume of fundus tissue affected by treatment, compared with other treatment modalities.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: feeder vessels,70,84,Anatomy choroidal,163,172,Anatomy fundus,280,286,Anatomy fundus tissue,305,318,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: CONCLUSIONS: Indocyanine green dye-enhanced photocoagulation of CNV feeder vessels, facilitated by use of a device that permits real-time visualization of the choroidal circulation while aiming the treatment laser beam, appears to minimize the amount of energy applied to the fundus and the volume of fundus tissue affected by treatment, compared with other treatment modalities.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: feeder vessels,70,84,Anatomy choroidal,163,172,Anatomy fundus,280,286,Anatomy fundus tissue,305,318,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In contrast, pellets from the CLA-fed animals contained fewer infiltrating cells, which formed limited branching cellular networks, the majority of which had collapsed lumen and no RBCs.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cells,77,82,Anatomy cellular networks,115,132,Anatomy lumen,170,175,Anatomy RBCs,183,187,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In contrast, pellets from the CLA-fed animals contained fewer infiltrating cells, which formed limited branching cellular networks, the majority of which had collapsed lumen and no RBCs.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cells,77,82,Anatomy cellular networks,115,132,Anatomy lumen,170,175,Anatomy RBCs,183,187,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Up-regulation of MMP activity, favoring proteolytic degradation of the basement membrane and extracellular matrix, has been linked to tumor growth and metastasis, as well as tumor-associated angiogenesis, whereas inhibition of MMP activity appears to restrict these processes.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: basement membrane,73,90,Anatomy extracellular matrix,95,115,Anatomy tumor,136,141,Anatomy tumor,176,181,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Up-regulation of MMP activity, favoring proteolytic degradation of the basement membrane and extracellular matrix, has been linked to tumor growth and metastasis, as well as tumor-associated angiogenesis, whereas inhibition of MMP activity appears to restrict these processes.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: basement membrane,73,90,Anatomy extracellular matrix,95,115,Anatomy tumor,136,141,Anatomy tumor,176,181,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Roles of cell adhesion molecules in tumor angiogenesis induced by cotransplantation of cancer and endothelial cells to nude rats.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,9,13,Anatomy tumor,36,41,Anatomy cancer,87,93,Anatomy endothelial cells,98,115,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Roles of cell adhesion molecules in tumor angiogenesis induced by cotransplantation of cancer and endothelial cells to nude rats.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,9,13,Anatomy tumor,36,41,Anatomy cancer,87,93,Anatomy endothelial cells,98,115,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: This in vitro morphological appearance was exactly reproduced in the in vivo tumors, which were formed when the mixture of A431 and F-2 cells at the ratio of 10: 1 were cotransplanted s. c. into the back of nude rats.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumors,77,83,Anatomy A431,123,127,Anatomy F - 2 cells,132,143,Anatomy back,201,205,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: This in vitro morphological appearance was exactly reproduced in the in vivo tumors, which were formed when the mixture of A431 and F-2 cells at the ratio of 10: 1 were cotransplanted s. c. into the back of nude rats.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumors,77,83,Anatomy A431,123,127,Anatomy F - 2 cells,132,143,Anatomy back,201,205,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: central nervous system,65,87,Anatomy CNS,90,93,Anatomy neurons,109,116,Anatomy glial cells,121,132,Anatomy
Task: Please carry out the NER task for the the text below. Text: Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: central nervous system,65,87,Anatomy CNS,90,93,Anatomy neurons,109,116,Anatomy glial cells,121,132,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Combined tracheal and esophageal stenting for palliation of tracheoesophageal symptoms from mediastinal lymphoma.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tracheal,9,17,Anatomy esophageal,22,32,Anatomy tracheoesophageal,60,77,Anatomy mediastinal lymphoma,92,112,Anatomy
Task: Please carry out the NER task for the the text below. Text: Combined tracheal and esophageal stenting for palliation of tracheoesophageal symptoms from mediastinal lymphoma.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tracheal,9,17,Anatomy esophageal,22,32,Anatomy tracheoesophageal,60,77,Anatomy mediastinal lymphoma,92,112,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Mediastinal lymphoma as a cause of tracheobronchial obstruction is uncommon, and a malignant tracheoesophageal fistula in the setting of mediastinal lymphoma is rare.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Mediastinal lymphoma,0,20,Anatomy tracheobronchial,35,51,Anatomy malignant tracheoesophageal fistula,83,118,Anatomy mediastinal lymphoma,137,157,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Mediastinal lymphoma as a cause of tracheobronchial obstruction is uncommon, and a malignant tracheoesophageal fistula in the setting of mediastinal lymphoma is rare.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Mediastinal lymphoma,0,20,Anatomy tracheobronchial,35,51,Anatomy malignant tracheoesophageal fistula,83,118,Anatomy mediastinal lymphoma,137,157,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: To investigate whether bee venom (BV) induces apoptosis, the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay, 4, 6-diamidino-2-phenylindole staining, flow cytometric analysis, and DNA fragmentation assay were performed on NCI-H1299 lung cancer cells treated with BV.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: venom,27,32,Anatomy BV,35,37,Anatomy NCI - H1299 lung cancer cells,344,373,Anatomy BV,387,389,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: To investigate whether bee venom (BV) induces apoptosis, the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assay, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay, 4, 6-diamidino-2-phenylindole staining, flow cytometric analysis, and DNA fragmentation assay were performed on NCI-H1299 lung cancer cells treated with BV.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: venom,27,32,Anatomy BV,35,37,Anatomy NCI - H1299 lung cancer cells,344,373,Anatomy BV,387,389,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Treatment of mice bearing a small ear tumor with a humanized antivascular endothelial growth factor antibody prevented the down-regulation of leukocyte-vessel wall interactions inside the tumor vessels compared with the nontreated group.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ear tumor,34,43,Anatomy leukocyte,144,153,Anatomy vessel wall,156,167,Anatomy tumor vessels,192,205,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Treatment of mice bearing a small ear tumor with a humanized antivascular endothelial growth factor antibody prevented the down-regulation of leukocyte-vessel wall interactions inside the tumor vessels compared with the nontreated group.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ear tumor,34,43,Anatomy leukocyte,144,153,Anatomy vessel wall,156,167,Anatomy tumor vessels,192,205,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Fluorescence-activated cell sorter analysis showed that isolated tumor ECs have suppressed levels of intercellular adhesion molecule 1 as compared with ECs from normal mouse tissues.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,25,29,Anatomy tumor ECs,67,76,Anatomy ECs,154,157,Anatomy tissues,176,183,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Fluorescence-activated cell sorter analysis showed that isolated tumor ECs have suppressed levels of intercellular adhesion molecule 1 as compared with ECs from normal mouse tissues.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cell,25,29,Anatomy tumor ECs,67,76,Anatomy ECs,154,157,Anatomy tissues,176,183,Anatomy
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Task: Please carry out the NER task for the the text below. Text: CONCLUSIONS: Galectin-3C is not overtly toxic, and is efficacious in reducing metastases and tumor volumes and weights in primary tumors in an orthotopic nude mouse model of human breast cancer.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: metastases,80,90,Anatomy tumor,95,100,Anatomy primary tumors,124,138,Anatomy breast cancer,182,195,Anatomy
Task: Please carry out the NER task for the the text below. Text: CONCLUSIONS: Galectin-3C is not overtly toxic, and is efficacious in reducing metastases and tumor volumes and weights in primary tumors in an orthotopic nude mouse model of human breast cancer.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: metastases,80,90,Anatomy tumor,95,100,Anatomy primary tumors,124,138,Anatomy breast cancer,182,195,Anatomy
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Task: Please carry out the NER task for the the text below. Text: In addition, most of transcripts of all genes could also be detected in other P. ginseng plant tissues such as stem, leaf and seed.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tissues,95,102,Anatomy stem,111,115,Anatomy leaf,117,121,Anatomy seed,126,130,Anatomy
Task: Please carry out the NER task for the the text below. Text: In addition, most of transcripts of all genes could also be detected in other P. ginseng plant tissues such as stem, leaf and seed.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tissues,95,102,Anatomy stem,111,115,Anatomy leaf,117,121,Anatomy seed,126,130,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Forty-seven specimens resected from patients with stage II and III squamous cell carcinoma (SCC) of the esophagus were studied using immunohistochemical staining.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: specimens,14,23,Anatomy squamous cell carcinoma,69,92,Anatomy SCC,95,98,Anatomy esophagus,107,116,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Forty-seven specimens resected from patients with stage II and III squamous cell carcinoma (SCC) of the esophagus were studied using immunohistochemical staining.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: specimens,14,23,Anatomy squamous cell carcinoma,69,92,Anatomy SCC,95,98,Anatomy esophagus,107,116,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Because the intravenously injected lipoplexes migrated within seconds to lungs, we checked whether the effects of immediate contact with serum correlate with lung lipofection efficiency of different DOTAP-based formulations.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: intravenously,12,25,Anatomy lungs,73,78,Anatomy serum,137,142,Anatomy lung,158,162,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Because the intravenously injected lipoplexes migrated within seconds to lungs, we checked whether the effects of immediate contact with serum correlate with lung lipofection efficiency of different DOTAP-based formulations.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: intravenously,12,25,Anatomy lungs,73,78,Anatomy serum,137,142,Anatomy lung,158,162,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Compared to controls, co-culture of MDA-MB-231 cells with stromal or osteoblastic cells induced an increase in number of osteoclasts and TRAP activities.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: MDA - MB - 231 cells,38,58,Anatomy stromal,64,71,Anatomy osteoblastic cells,75,93,Anatomy osteoclasts,127,138,Anatomy
Task: Please carry out the NER task for the the text below. Text: Compared to controls, co-culture of MDA-MB-231 cells with stromal or osteoblastic cells induced an increase in number of osteoclasts and TRAP activities.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: MDA - MB - 231 cells,38,58,Anatomy stromal,64,71,Anatomy osteoblastic cells,75,93,Anatomy osteoclasts,127,138,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The interaction between the vascular endothelium and hemodynamic forces (and more specifically, fluid shear stress), induced by the flow of blood, plays a major role in vascular remodeling and in new blood vessels formation via a process termed arteriogenesis.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: vascular endothelium,28,48,Anatomy blood,141,146,Anatomy vascular,170,178,Anatomy blood vessels,201,214,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The interaction between the vascular endothelium and hemodynamic forces (and more specifically, fluid shear stress), induced by the flow of blood, plays a major role in vascular remodeling and in new blood vessels formation via a process termed arteriogenesis.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: vascular endothelium,28,48,Anatomy blood,141,146,Anatomy vascular,170,178,Anatomy blood vessels,201,214,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Microvascular density and vascular endothelial growth factor immunoreactivity as predictors of regional lymph node metastasis from betel-associated oral squamous cell carcinoma.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Microvascular,0,13,Anatomy lymph node,104,114,Anatomy betel,131,136,Anatomy oral squamous cell carcinoma,150,178,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Microvascular density and vascular endothelial growth factor immunoreactivity as predictors of regional lymph node metastasis from betel-associated oral squamous cell carcinoma.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Microvascular,0,13,Anatomy lymph node,104,114,Anatomy betel,131,136,Anatomy oral squamous cell carcinoma,150,178,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: The incidence of high-grade lesions (high-grade dysplasia/carcinoma in situ and invasive adenocarcinoma) in the folate-supplemented group was 46% lower than that in the control group (35.3% versus 65.1%, P = 0.009).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: high - grade lesions,17,37,Anatomy high - grade dysplasia,40,62,Anatomy carcinoma in situ,65,82,Anatomy invasive adenocarcinoma,87,110,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: The incidence of high-grade lesions (high-grade dysplasia/carcinoma in situ and invasive adenocarcinoma) in the folate-supplemented group was 46% lower than that in the control group (35.3% versus 65.1%, P = 0.009).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: high - grade lesions,17,37,Anatomy high - grade dysplasia,40,62,Anatomy carcinoma in situ,65,82,Anatomy invasive adenocarcinoma,87,110,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Gliomas are the most common primary tumours of the central nervous system, with nearly 15, 000 diagnosed annually in the United States and a lethality approaching 80% within the first year of glioblastoma diagnosis.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Gliomas,0,7,Anatomy primary tumours,28,43,Anatomy central nervous system,51,73,Anatomy glioblastoma,192,204,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Gliomas are the most common primary tumours of the central nervous system, with nearly 15, 000 diagnosed annually in the United States and a lethality approaching 80% within the first year of glioblastoma diagnosis.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Gliomas,0,7,Anatomy primary tumours,28,43,Anatomy central nervous system,51,73,Anatomy glioblastoma,192,204,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: In mice, xenografts of human glioblastoma U87MG, which has decreased expression of ING4, grow significantly faster and have higher vascular volume fractions than control tumours.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: xenografts,9,19,Anatomy glioblastoma U87MG,29,47,Anatomy vascular,131,139,Anatomy tumours,170,177,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: In mice, xenografts of human glioblastoma U87MG, which has decreased expression of ING4, grow significantly faster and have higher vascular volume fractions than control tumours.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: xenografts,9,19,Anatomy glioblastoma U87MG,29,47,Anatomy vascular,131,139,Anatomy tumours,170,177,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: With the discovery that TGFbeta1 was a potent growth inhibitor of epithelial cells, and the identification of inactivating mutations within the TGFbeta1 signaling pathway in cancers it became clear that TGFbeta1 signaling is a tumor suppressor pathway for early stages of cancer.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: epithelial cells,66,82,Anatomy cancers,174,181,Anatomy tumor,227,232,Anatomy cancer,272,278,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: With the discovery that TGFbeta1 was a potent growth inhibitor of epithelial cells, and the identification of inactivating mutations within the TGFbeta1 signaling pathway in cancers it became clear that TGFbeta1 signaling is a tumor suppressor pathway for early stages of cancer.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: epithelial cells,66,82,Anatomy cancers,174,181,Anatomy tumor,227,232,Anatomy cancer,272,278,Anatomy
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Task: Please carry out the NER task for the the text below. Text: After removal of fibroblasts by exposure to G-418, the tumor cells exhibited increased metastatic ability and human K-ras oncogene mRNA, suggesting an intimate interaction between H-3 cells and fibroblasts influencing the function of transfected human K-ras oncogene.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: fibroblasts,17,28,Anatomy tumor cells,57,68,Anatomy H - 3 cells,184,195,Anatomy fibroblasts,200,211,Anatomy
Task: Please carry out the NER task for the the text below. Text: After removal of fibroblasts by exposure to G-418, the tumor cells exhibited increased metastatic ability and human K-ras oncogene mRNA, suggesting an intimate interaction between H-3 cells and fibroblasts influencing the function of transfected human K-ras oncogene.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: fibroblasts,17,28,Anatomy tumor cells,57,68,Anatomy H - 3 cells,184,195,Anatomy fibroblasts,200,211,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Immunohistochemical analysis revealed Fas-positive cells and apoptotic cells preferentially within the proximal colon region, clearly at the site of bovine lactoferrin-mediated tumor inhibition.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Fas - positive cells,38,58,Anatomy cells,73,78,Anatomy colon,114,119,Anatomy tumor,181,186,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Immunohistochemical analysis revealed Fas-positive cells and apoptotic cells preferentially within the proximal colon region, clearly at the site of bovine lactoferrin-mediated tumor inhibition.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Fas - positive cells,38,58,Anatomy cells,73,78,Anatomy colon,114,119,Anatomy tumor,181,186,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: However, how the tumor suppressive functions of p53 become concerted with the extracellular cues arriving at the cell surface during tissue homeostasis, remains largely unknown.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumor,17,22,Anatomy extracellular,78,91,Anatomy cell surface,113,125,Anatomy tissue,133,139,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: However, how the tumor suppressive functions of p53 become concerted with the extracellular cues arriving at the cell surface during tissue homeostasis, remains largely unknown.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumor,17,22,Anatomy extracellular,78,91,Anatomy cell surface,113,125,Anatomy tissue,133,139,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: We hypothesized that IGF-1-transfected smooth muscle cells (SMCs) would enhance cell survival and improve engraftment after cell transplantation.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: smooth muscle cells,43,62,Anatomy SMCs,65,69,Anatomy cell,85,89,Anatomy cell,129,133,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: We hypothesized that IGF-1-transfected smooth muscle cells (SMCs) would enhance cell survival and improve engraftment after cell transplantation.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: smooth muscle cells,43,62,Anatomy SMCs,65,69,Anatomy cell,85,89,Anatomy cell,129,133,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Completion coronary flow was 88+/-49 mL/min for the RA, 60+/-45 mL/min for the ITA, and 140+/-70 mL/min for both limbs simultaneously to give a flow reserve (vs simultaneous free flow) of 160% or 1.6.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: coronary,11,19,Anatomy RA,58,60,Anatomy ITA,91,94,Anatomy limbs,131,136,Anatomy
Task: Please carry out the NER task for the the text below. Text: Completion coronary flow was 88+/-49 mL/min for the RA, 60+/-45 mL/min for the ITA, and 140+/-70 mL/min for both limbs simultaneously to give a flow reserve (vs simultaneous free flow) of 160% or 1.6.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: coronary,11,19,Anatomy RA,58,60,Anatomy ITA,91,94,Anatomy limbs,131,136,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In the present study the effects of the 48-hour administration of granulocyte-macrophage colony-stimulating factor (GM-CSF) (100 U/mL) or interleukin-3 (IL-3) (100 U/mL) on the proliferative activity of leukemic cells and on the intracellular metabolism and cytotoxic efficacy of a subsequent 12-hour application of cytosine arabinoside (ara-C) at doses of 0.1, 1.0, 10.0, and 100.0 mumol/L were evaluated on bone marrow cells from 17 patients with acute myeloid leukemia.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: leukemic cells,223,237,Anatomy intracellular,249,262,Anatomy bone marrow cells,440,457,Anatomy acute myeloid leukemia,480,502,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In the present study the effects of the 48-hour administration of granulocyte-macrophage colony-stimulating factor (GM-CSF) (100 U/mL) or interleukin-3 (IL-3) (100 U/mL) on the proliferative activity of leukemic cells and on the intracellular metabolism and cytotoxic efficacy of a subsequent 12-hour application of cytosine arabinoside (ara-C) at doses of 0.1, 1.0, 10.0, and 100.0 mumol/L were evaluated on bone marrow cells from 17 patients with acute myeloid leukemia.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: leukemic cells,223,237,Anatomy intracellular,249,262,Anatomy bone marrow cells,440,457,Anatomy acute myeloid leukemia,480,502,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Hence, GM-CSF and IL-3 enhance the intracellular metabolism of ara-C and its incorporation into the DNA of leukemic cells leading to a higher antileukemic activity of ara-C on clonogenic leukemic cells (CFU-L).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: intracellular,39,52,Anatomy leukemic cells,113,127,Anatomy clonogenic leukemic cells,184,209,Anatomy CFU - L,212,219,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Hence, GM-CSF and IL-3 enhance the intracellular metabolism of ara-C and its incorporation into the DNA of leukemic cells leading to a higher antileukemic activity of ara-C on clonogenic leukemic cells (CFU-L).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: intracellular,39,52,Anatomy leukemic cells,113,127,Anatomy clonogenic leukemic cells,184,209,Anatomy CFU - L,212,219,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: We hypothesized that 1) MCT expression in malignant tumors may differ from normal tissue in quantity, isoform, or both; and 2) silencing MCT expression would induce intracellular acidification, resulting in decreased proliferation and/or increased cell death.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: malignant tumors,42,58,Anatomy tissue,82,88,Anatomy intracellular,165,178,Anatomy cell,250,254,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: We hypothesized that 1) MCT expression in malignant tumors may differ from normal tissue in quantity, isoform, or both; and 2) silencing MCT expression would induce intracellular acidification, resulting in decreased proliferation and/or increased cell death.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: malignant tumors,42,58,Anatomy tissue,82,88,Anatomy intracellular,165,178,Anatomy cell,250,254,Anatomy
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Task: Please carry out the NER task for the the text below. Text: MCTs that were abundant or specific to glioma then were targeted in the model U-87 MG glioma cell line via small interfering ribonucleic acid-mediated gene silencing and tested for inhibition of lactate efflux, intracellular pH changes, reduced proliferation, and/or induction of cell death.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: glioma,39,45,Anatomy U - 87 MG glioma cell line,78,104,Anatomy intracellular,215,228,Anatomy cell,286,290,Anatomy
Task: Please carry out the NER task for the the text below. Text: MCTs that were abundant or specific to glioma then were targeted in the model U-87 MG glioma cell line via small interfering ribonucleic acid-mediated gene silencing and tested for inhibition of lactate efflux, intracellular pH changes, reduced proliferation, and/or induction of cell death.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: glioma,39,45,Anatomy U - 87 MG glioma cell line,78,104,Anatomy intracellular,215,228,Anatomy cell,286,290,Anatomy
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Task: Please carry out the NER task for the the text below. Text: To identify the underlying mechanism involved in such growth-factor/serum independent growth of Galpha (12) QL-transformed NIH3T3, we carried out a two-dimensional differential proteome analysis of Galpha (12) QL-transformed NIH3T3 cells and cells expressing vector control.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: serum,72,77,Anatomy NIH3T3,130,136,Anatomy NIH3T3 cells,237,249,Anatomy cells,254,259,Anatomy
Task: Please carry out the NER task for the the text below. Text: To identify the underlying mechanism involved in such growth-factor/serum independent growth of Galpha (12) QL-transformed NIH3T3, we carried out a two-dimensional differential proteome analysis of Galpha (12) QL-transformed NIH3T3 cells and cells expressing vector control.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: serum,72,77,Anatomy NIH3T3,130,136,Anatomy NIH3T3 cells,237,249,Anatomy cells,254,259,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Finally, in vivo, in a xenograft model of head and neck squamous cell carcinoma using UM-SCC-11A cells, 2ME2 exhibited antitumor and antiangiogenic activity, as measured by CD31 immunostaining.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: xenograft,23,32,Anatomy head and neck squamous cell carcinoma,42,79,Anatomy UM - SCC - 11A cells,86,106,Anatomy antitumor,123,132,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Finally, in vivo, in a xenograft model of head and neck squamous cell carcinoma using UM-SCC-11A cells, 2ME2 exhibited antitumor and antiangiogenic activity, as measured by CD31 immunostaining.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: xenograft,23,32,Anatomy head and neck squamous cell carcinoma,42,79,Anatomy UM - SCC - 11A cells,86,106,Anatomy antitumor,123,132,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: In a subset of neuroblastomas, a spontaneous neuronal to neuroendocrine differentiation occurs in areas adjacent to necrotic zones.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: neuroblastomas,15,29,Anatomy neuronal,45,53,Anatomy neuroendocrine,57,71,Anatomy necrotic zones,116,130,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: In a subset of neuroblastomas, a spontaneous neuronal to neuroendocrine differentiation occurs in areas adjacent to necrotic zones.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: neuroblastomas,15,29,Anatomy neuronal,45,53,Anatomy neuroendocrine,57,71,Anatomy necrotic zones,116,130,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: With regard to differentiation, hypoxic cells lost their neuronal/neuroendocrine features and gained marker gene expression associated with an immature, neural crest-like phenotype.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: hypoxic cells,32,45,Anatomy neuronal,57,65,Anatomy neuroendocrine,68,82,Anatomy neural crest,155,167,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: With regard to differentiation, hypoxic cells lost their neuronal/neuroendocrine features and gained marker gene expression associated with an immature, neural crest-like phenotype.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: hypoxic cells,32,45,Anatomy neuronal,57,65,Anatomy neuroendocrine,68,82,Anatomy neural crest,155,167,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, can act in tumor-induced angiogenesis by binding to specific receptors on the surface of endothelial cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endothelial cell,47,63,Anatomy tumor,95,100,Anatomy surface,164,171,Anatomy endothelial cells,175,192,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, can act in tumor-induced angiogenesis by binding to specific receptors on the surface of endothelial cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: endothelial cell,47,63,Anatomy tumor,95,100,Anatomy surface,164,171,Anatomy endothelial cells,175,192,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Here, the pattern of expression of angiogenin during the transition from normal breast tissue to ductal carcinoma in situ and invasive carcinoma is reported together with the correlates between the level of angiogenin in 239 invasive carcinomas and standard clinicopathological parameters, hypoxia-inducible factor (HIF)-1 alpha and the HIF-1 alpha target gene DEC-1.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: breast tissue,80,93,Anatomy ductal carcinoma in situ,97,121,Anatomy invasive carcinoma,126,144,Anatomy invasive carcinomas,225,244,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Here, the pattern of expression of angiogenin during the transition from normal breast tissue to ductal carcinoma in situ and invasive carcinoma is reported together with the correlates between the level of angiogenin in 239 invasive carcinomas and standard clinicopathological parameters, hypoxia-inducible factor (HIF)-1 alpha and the HIF-1 alpha target gene DEC-1.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: breast tissue,80,93,Anatomy ductal carcinoma in situ,97,121,Anatomy invasive carcinoma,126,144,Anatomy invasive carcinomas,225,244,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: Human cervical cancer cells (CaSki and SiHa) were injected into the flanks of nude mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cervical cancer cells,6,27,Anatomy CaSki,30,35,Anatomy SiHa,40,44,Anatomy flanks,69,75,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: Human cervical cancer cells (CaSki and SiHa) were injected into the flanks of nude mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cervical cancer cells,6,27,Anatomy CaSki,30,35,Anatomy SiHa,40,44,Anatomy flanks,69,75,Anatomy
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Task: Please carry out the NER task for the the text below. Text: p63, a p53 homologue, is a myoepithelial cell marker in the normal mammary gland but p63-positive neoplastic cells may be found in up to 11% of invasive breast carcinomas.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: myoepithelial cell,27,45,Anatomy mammary gland,67,80,Anatomy p63 - positive neoplastic cells,85,116,Anatomy invasive breast carcinomas,146,172,Anatomy
Task: Please carry out the NER task for the the text below. Text: p63, a p53 homologue, is a myoepithelial cell marker in the normal mammary gland but p63-positive neoplastic cells may be found in up to 11% of invasive breast carcinomas.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: myoepithelial cell,27,45,Anatomy mammary gland,67,80,Anatomy p63 - positive neoplastic cells,85,116,Anatomy invasive breast carcinomas,146,172,Anatomy
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Task: Please carry out the named entity recognition task for the the text below. Text: We show that LRP-1 deficiency in murine embryonic fibroblasts (MEFs) is associated with increased levels of type III collagen and pigment epithelium-derived factor, which accumulate in the substratum surrounding cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: embryonic fibroblasts,42,63,Anatomy MEFs,66,70,Anatomy substratum,194,204,Anatomy cells,217,222,Anatomy
Task: Please carry out the named entity recognition task for the the text below. Text: We show that LRP-1 deficiency in murine embryonic fibroblasts (MEFs) is associated with increased levels of type III collagen and pigment epithelium-derived factor, which accumulate in the substratum surrounding cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: embryonic fibroblasts,42,63,Anatomy MEFs,66,70,Anatomy substratum,194,204,Anatomy cells,217,222,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: After decapitation of the rats, trunk blood was obtained, and the ileum, liver, and kidney were removed for histological examination and for the measurement of malondialdehyde (MDA) and glutathione (GSH) levels, myeloperoxidase (MPO) activity, and collagen content.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: trunk blood,32,43,Anatomy ileum,66,71,Anatomy liver,73,78,Anatomy kidney,84,90,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: After decapitation of the rats, trunk blood was obtained, and the ileum, liver, and kidney were removed for histological examination and for the measurement of malondialdehyde (MDA) and glutathione (GSH) levels, myeloperoxidase (MPO) activity, and collagen content.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: trunk blood,32,43,Anatomy ileum,66,71,Anatomy liver,73,78,Anatomy kidney,84,90,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Severe degeneration of the intestinal mucosa, liver parenchyma, and glomerular and tubular epithelium observed in the saline-treated MTX group was improved by L-Car treatment.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: intestinal mucosa,27,44,Anatomy liver parenchyma,46,62,Anatomy glomerular,68,78,Anatomy tubular epithelium,83,101,Anatomy
Task: Please carry out the NER task for the the text below. Text: Severe degeneration of the intestinal mucosa, liver parenchyma, and glomerular and tubular epithelium observed in the saline-treated MTX group was improved by L-Car treatment.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: intestinal mucosa,27,44,Anatomy liver parenchyma,46,62,Anatomy glomerular,68,78,Anatomy tubular epithelium,83,101,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To directly address whether pericyte dysfunction increases the metastatic potential of solid tumors, we studied beta cell tumorigenesis in primary pericyte-deficient Pdgfb (ret/ret) mice.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pericyte,28,36,Anatomy solid tumors,87,99,Anatomy beta cell,112,121,Anatomy pericyte,147,155,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To directly address whether pericyte dysfunction increases the metastatic potential of solid tumors, we studied beta cell tumorigenesis in primary pericyte-deficient Pdgfb (ret/ret) mice.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pericyte,28,36,Anatomy solid tumors,87,99,Anatomy beta cell,112,121,Anatomy pericyte,147,155,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: A novel method of assessing vascular endothelial function in cancer is via the quantification of circulating endothelial cells (CEC).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: vascular endothelial,28,48,Anatomy cancer,61,67,Anatomy circulating endothelial cells,97,126,Anatomy CEC,129,132,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: A novel method of assessing vascular endothelial function in cancer is via the quantification of circulating endothelial cells (CEC).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: vascular endothelial,28,48,Anatomy cancer,61,67,Anatomy circulating endothelial cells,97,126,Anatomy CEC,129,132,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Another interesting cell type is the endothelial progenitor cell (EPC), whose numbers increase in the presence of vascular damage.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell,20,24,Anatomy endothelial progenitor cell,37,64,Anatomy EPC,67,70,Anatomy vascular,115,123,Anatomy
Task: Please carry out the NER task for the the text below. Text: Another interesting cell type is the endothelial progenitor cell (EPC), whose numbers increase in the presence of vascular damage.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cell,20,24,Anatomy endothelial progenitor cell,37,64,Anatomy EPC,67,70,Anatomy vascular,115,123,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Some investigators, based on the results of cortical stimulation response, functional imaging, EEG recordings of seizures, and lesional studies, have suggested that cardiac sympathetic and parasympathetic function may be lateralized, with sympathetic representation lateralized to the right insula, and parasympathetic, to the left.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cortical,44,52,Anatomy cardiac,165,172,Anatomy right insula,285,297,Anatomy left,327,331,Anatomy
Task: Please carry out the NER task for the the text below. Text: Some investigators, based on the results of cortical stimulation response, functional imaging, EEG recordings of seizures, and lesional studies, have suggested that cardiac sympathetic and parasympathetic function may be lateralized, with sympathetic representation lateralized to the right insula, and parasympathetic, to the left.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: cortical,44,52,Anatomy cardiac,165,172,Anatomy right insula,285,297,Anatomy left,327,331,Anatomy
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Task: Please carry out the NER task for the the text below. Text: This study shows that the acute response to zymosan-induced inflammation in the rat spinal cord white matter causes a gradual appearance of phagocytic microglia/macrophages and delayed FJB staining of the inflammatory cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: spinal cord white matter,86,110,Anatomy phagocytic microglia,142,162,Anatomy macrophages,165,176,Anatomy inflammatory cells,209,227,Anatomy
Task: Please carry out the NER task for the the text below. Text: This study shows that the acute response to zymosan-induced inflammation in the rat spinal cord white matter causes a gradual appearance of phagocytic microglia/macrophages and delayed FJB staining of the inflammatory cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: spinal cord white matter,86,110,Anatomy phagocytic microglia,142,162,Anatomy macrophages,165,176,Anatomy inflammatory cells,209,227,Anatomy
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Task: Please carry out the NER task for the the text below. Text: Proportional changes of lymphocyte subsets in the peripheral blood were monitored by two-color flow-cytometry in seven leukemia patients who had received allogenic bone marrow transplantation (BMT).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: lymphocyte,24,34,Anatomy peripheral blood,50,66,Anatomy leukemia,123,131,Anatomy bone marrow,168,179,Anatomy
Task: Please carry out the NER task for the the text below. Text: Proportional changes of lymphocyte subsets in the peripheral blood were monitored by two-color flow-cytometry in seven leukemia patients who had received allogenic bone marrow transplantation (BMT).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: lymphocyte,24,34,Anatomy peripheral blood,50,66,Anatomy leukemia,123,131,Anatomy bone marrow,168,179,Anatomy
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Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In vitro studies using monolayer cultures of human tumor cell lines have shown that 2-DG selectively inhibits energy-dependent DNA repair and cellular recovery processes in cancer cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: monolayer cultures,23,41,Anatomy tumor cell lines,51,67,Anatomy cellular,146,154,Anatomy cancer cells,177,189,Anatomy
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In vitro studies using monolayer cultures of human tumor cell lines have shown that 2-DG selectively inhibits energy-dependent DNA repair and cellular recovery processes in cancer cells.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: monolayer cultures,23,41,Anatomy tumor cell lines,51,67,Anatomy cellular,146,154,Anatomy cancer cells,177,189,Anatomy
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Task: Please carry out the NER task for the the text below. Text: However, monolayer cultures differ greatly from the complex environmental conditions generated in solid tumors that develop inhomogeneous hypoxic and necrotic regions.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: monolayer cultures,9,27,Anatomy solid tumors,98,110,Anatomy inhomogeneous hypoxic,124,145,Anatomy necrotic regions,150,166,Anatomy
Task: Please carry out the NER task for the the text below. Text: However, monolayer cultures differ greatly from the complex environmental conditions generated in solid tumors that develop inhomogeneous hypoxic and necrotic regions.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: monolayer cultures,9,27,Anatomy solid tumors,98,110,Anatomy inhomogeneous hypoxic,124,145,Anatomy necrotic regions,150,166,Anatomy
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Task: Please carry out the NER task for the the text below. Text: In contrast, multicellular spheroids mimic heterogeneous cellular behavior and the consequent functional characteristics of in vivo solid tumors, and serve as important in vitro model to investigate tumor biology and responses to potential therapeutic agents.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: multicellular spheroids,13,36,Anatomy cellular,57,65,Anatomy solid tumors,132,144,Anatomy tumor,199,204,Anatomy
Task: Please carry out the NER task for the the text below. Text: In contrast, multicellular spheroids mimic heterogeneous cellular behavior and the consequent functional characteristics of in vivo solid tumors, and serve as important in vitro model to investigate tumor biology and responses to potential therapeutic agents.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: multicellular spheroids,13,36,Anatomy cellular,57,65,Anatomy solid tumors,132,144,Anatomy tumor,199,204,Anatomy
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NER data.

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