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Task: Please carry out the NER task for the the text below. Text: (B) Contact-dependent stimulation of iDC TNF-alpha production by NK cells was tested under the following conditions: DCs alone (gray bars); NK+ DC (1: 5) (black bars); NK/DC (1: 5) trans-wells (striped bars).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: iDC,40,43,Anatomy NK cells,70,78,Anatomy DCs,122,125,Anatomy NK,146,148,Anatomy DC,151,153,Anatomy NK,177,179,Anatomy DC,182,184,Anatomy	Task: Please carry out the NER task for the the text below. Text: (B) Contact-dependent stimulation of iDC TNF-alpha production by NK cells was tested under the following conditions: DCs alone (gray bars); NK+ DC (1: 5) (black bars); NK/DC (1: 5) trans-wells (striped bars).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: iDC,40,43,Anatomy NK cells,70,78,Anatomy DCs,122,125,Anatomy NK,146,148,Anatomy DC,151,153,Anatomy NK,177,179,Anatomy DC,182,184,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: At the 5: 1 (NK/DC) ratio, NK cell-mediated destruction of the iDCs was the dominant feature, whereas at the low ratio (1: 5) the same NK cells promoted iDCs survival compared with iDCs alone over the same period (Fig. 3 A).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK,14,16,Anatomy DC,19,21,Anatomy NK cell,30,37,Anatomy iDCs,68,72,Anatomy NK cells,141,149,Anatomy iDCs,159,163,Anatomy iDCs,187,191,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: At the 5: 1 (NK/DC) ratio, NK cell-mediated destruction of the iDCs was the dominant feature, whereas at the low ratio (1: 5) the same NK cells promoted iDCs survival compared with iDCs alone over the same period (Fig. 3 A).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NK,14,16,Anatomy DC,19,21,Anatomy NK cell,30,37,Anatomy iDCs,68,72,Anatomy NK cells,141,149,Anatomy iDCs,159,163,Anatomy iDCs,187,191,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: There was local ulceration of the pleura, while, beyond this ulcer, the tumor formed a thick cake of discohesive tumor cells lining the pleural membrane (Figure 2 (c)), with only focal, microscopic invasion into the fatty tissue of the parietal pleura.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pleura,34,40,Anatomy ulcer,61,66,Anatomy tumor,72,77,Anatomy discohesive tumor cells,101,124,Anatomy pleural membrane,136,152,Anatomy fatty tissue,218,230,Anatomy parietal pleura,238,253,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: There was local ulceration of the pleura, while, beyond this ulcer, the tumor formed a thick cake of discohesive tumor cells lining the pleural membrane (Figure 2 (c)), with only focal, microscopic invasion into the fatty tissue of the parietal pleura.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pleura,34,40,Anatomy ulcer,61,66,Anatomy tumor,72,77,Anatomy discohesive tumor cells,101,124,Anatomy pleural membrane,136,152,Anatomy fatty tissue,218,230,Anatomy parietal pleura,238,253,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: However, generalized and distinctive dietary patterns do exist, including olive oil as the main source of visible fat, employed both in cooking and as a dressing, moderate fish and poultry but low red meat consumption, high intake of vegetables, fruits, legumes, nuts, and whole-grain cereals [ 4, 14-16].. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: olive oil,74,83,Anatomy fat,114,117,Anatomy red meat,197,205,Anatomy vegetables,234,244,Anatomy fruits,246,252,Anatomy legumes,254,261,Anatomy nuts,263,267,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: However, generalized and distinctive dietary patterns do exist, including olive oil as the main source of visible fat, employed both in cooking and as a dressing, moderate fish and poultry but low red meat consumption, high intake of vegetables, fruits, legumes, nuts, and whole-grain cereals [ 4, 14-16].. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: olive oil,74,83,Anatomy fat,114,117,Anatomy red meat,197,205,Anatomy vegetables,234,244,Anatomy fruits,246,252,Anatomy legumes,254,261,Anatomy nuts,263,267,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: F-2 cells cultured on Matrigel showed evident tube formation, and coculture of F-2 cells with A431 cells led to the formation of A431 cell nests constantly surrounded by tube-like networks consisting of F-2 cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: F - 2 cells,0,11,Anatomy tube,48,52,Anatomy F - 2 cells,81,92,Anatomy A431 cells,98,108,Anatomy A431 cell,133,142,Anatomy tube - like networks,174,194,Anatomy F - 2 cells,209,220,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: F-2 cells cultured on Matrigel showed evident tube formation, and coculture of F-2 cells with A431 cells led to the formation of A431 cell nests constantly surrounded by tube-like networks consisting of F-2 cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: F - 2 cells,0,11,Anatomy tube,48,52,Anatomy F - 2 cells,81,92,Anatomy A431 cells,98,108,Anatomy A431 cell,133,142,Anatomy tube - like networks,174,194,Anatomy F - 2 cells,209,220,Anatomy	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: The tumors of A431 supplemented with F-2 cells were profoundly vascularized throughout by the tubular structures formed by F-2 cells, the lumen of which contained the host rat blood cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumors,4,10,Anatomy A431,14,18,Anatomy F - 2 cells,37,48,Anatomy tubular structures,96,114,Anatomy F - 2 cells,125,136,Anatomy lumen,142,147,Anatomy blood cells,180,191,Anatomy	Task: Please carry out the named entity recognition task for the the text below. Text: The tumors of A431 supplemented with F-2 cells were profoundly vascularized throughout by the tubular structures formed by F-2 cells, the lumen of which contained the host rat blood cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: tumors,4,10,Anatomy A431,14,18,Anatomy F - 2 cells,37,48,Anatomy tubular structures,96,114,Anatomy F - 2 cells,125,136,Anatomy lumen,142,147,Anatomy blood cells,180,191,Anatomy	[]	null
Task: Please carry out the NER task for the the text below. Text: These results indicate that the interaction of tumor cells and endothelial cells in orderly tumor angiomorphogenesis is highly dependent on the action of cell adhesion molecules mediating the adhesion of cancer cells to endothelial cells, inhibition of which remarkably retards tumor growth and angiogenesis.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tumor cells,47,58,Anatomy endothelial cells,63,80,Anatomy tumor,92,97,Anatomy cell,154,158,Anatomy cancer cells,204,216,Anatomy endothelial cells,220,237,Anatomy tumor,278,283,Anatomy	Task: Please carry out the NER task for the the text below. Text: These results indicate that the interaction of tumor cells and endothelial cells in orderly tumor angiomorphogenesis is highly dependent on the action of cell adhesion molecules mediating the adhesion of cancer cells to endothelial cells, inhibition of which remarkably retards tumor growth and angiogenesis.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: tumor cells,47,58,Anatomy endothelial cells,63,80,Anatomy tumor,92,97,Anatomy cell,154,158,Anatomy cancer cells,204,216,Anatomy endothelial cells,220,237,Anatomy tumor,278,283,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Leukocyte-vessel wall interactions were studied both within and outside small tumors growing in the ear, and in ear microvessels of mice with a large tumor growing on their flank.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Leukocyte,0,9,Anatomy vessel wall,12,23,Anatomy tumors,80,86,Anatomy ear,102,105,Anatomy ear microvessels,114,130,Anatomy tumor,152,157,Anatomy flank,175,180,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Leukocyte-vessel wall interactions were studied both within and outside small tumors growing in the ear, and in ear microvessels of mice with a large tumor growing on their flank.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Leukocyte,0,9,Anatomy vessel wall,12,23,Anatomy tumors,80,86,Anatomy ear,102,105,Anatomy ear microvessels,114,130,Anatomy tumor,152,157,Anatomy flank,175,180,Anatomy	[]	null
Task: Please carry out the NER task for the the text below. Text: METHODS: Expression of MMP-9 was studied in human NPC cell lines cultured in vitro: CNE1 (well differentiated cell line of NPC) and CNE1-GL (CNE1 cell line transfected with an eukaryotic LMP1-expression plasmid) by SP immunohistochemistry and Western blot analysis.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NPC cell lines,52,66,Anatomy CNE1,86,90,Anatomy cell line,113,122,Anatomy NPC,126,129,Anatomy CNE1 - GL,135,144,Anatomy CNE1 cell line,147,161,Anatomy plasmid,211,218,Anatomy	Task: Please carry out the NER task for the the text below. Text: METHODS: Expression of MMP-9 was studied in human NPC cell lines cultured in vitro: CNE1 (well differentiated cell line of NPC) and CNE1-GL (CNE1 cell line transfected with an eukaryotic LMP1-expression plasmid) by SP immunohistochemistry and Western blot analysis.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: NPC cell lines,52,66,Anatomy CNE1,86,90,Anatomy cell line,113,122,Anatomy NPC,126,129,Anatomy CNE1 - GL,135,144,Anatomy CNE1 cell line,147,161,Anatomy plasmid,211,218,Anatomy	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: In order to elucidate a mechanism for cancer-induced osteoclastogenesis, cells from a human breast cancer line, MDA-MB-231, were directly co-cultured with ST2, MC3T3-E1, or with primary mouse calvarial cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cancer,38,44,Anatomy cells,75,80,Anatomy breast cancer line,94,112,Anatomy MDA - MB - 231,114,128,Anatomy ST2,163,166,Anatomy MC3T3 - E1,168,178,Anatomy calvarial cells,202,217,Anatomy	Task: Please carry out the named entity recognition task for the the text below. Text: In order to elucidate a mechanism for cancer-induced osteoclastogenesis, cells from a human breast cancer line, MDA-MB-231, were directly co-cultured with ST2, MC3T3-E1, or with primary mouse calvarial cells.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cancer,38,44,Anatomy cells,75,80,Anatomy breast cancer line,94,112,Anatomy MDA - MB - 231,114,128,Anatomy ST2,163,166,Anatomy MC3T3 - E1,168,178,Anatomy calvarial cells,202,217,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: A clone of NIH3T3 transformant (H-3), obtained by transfecting genomic DNA of a human colon carcinoma cell line, contains human K-ras oncogene and yields metastatic pulmonary nodules after intravenous injection of the cells into nude mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: clone,2,7,Anatomy NIH3T3 transformant,11,30,Anatomy H - 3,33,38,Anatomy colon carcinoma cell line,89,114,Anatomy metastatic pulmonary nodules,159,187,Anatomy intravenous,194,205,Anatomy cells,223,228,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: A clone of NIH3T3 transformant (H-3), obtained by transfecting genomic DNA of a human colon carcinoma cell line, contains human K-ras oncogene and yields metastatic pulmonary nodules after intravenous injection of the cells into nude mice.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: clone,2,7,Anatomy NIH3T3 transformant,11,30,Anatomy H - 3,33,38,Anatomy colon carcinoma cell line,89,114,Anatomy metastatic pulmonary nodules,159,187,Anatomy intravenous,194,205,Anatomy cells,223,228,Anatomy	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: The most frequent sites of metastases are the lung and lymph nodes, followed by the bones and liver, while duodenal involvement is rare.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: sites,18,23,Anatomy metastases,27,37,Anatomy lung,46,50,Anatomy lymph nodes,55,66,Anatomy bones,84,89,Anatomy liver,94,99,Anatomy duodenal,107,115,Anatomy	Task: Please carry out the named entity recognition task for the the text below. Text: The most frequent sites of metastases are the lung and lymph nodes, followed by the bones and liver, while duodenal involvement is rare.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: sites,18,23,Anatomy metastases,27,37,Anatomy lung,46,50,Anatomy lymph nodes,55,66,Anatomy bones,84,89,Anatomy liver,94,99,Anatomy duodenal,107,115,Anatomy	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: RESULTS: Opticin was immunolocalised to the basal cell surface and basement membrane material of the non-pigmented CBE in nine donor eyes as well as four hyperplastic lesions of the CBE (Fuchs's adenoma).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: basal cell surface,44,62,Anatomy basement membrane material,67,93,Anatomy non - pigmented CBE,101,120,Anatomy eyes,135,139,Anatomy hyperplastic lesions,156,176,Anatomy CBE,184,187,Anatomy Fuchs ' s adenoma,190,207,Anatomy	Task: Please carry out the named entity recognition task for the the text below. Text: RESULTS: Opticin was immunolocalised to the basal cell surface and basement membrane material of the non-pigmented CBE in nine donor eyes as well as four hyperplastic lesions of the CBE (Fuchs's adenoma).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: basal cell surface,44,62,Anatomy basement membrane material,67,93,Anatomy non - pigmented CBE,101,120,Anatomy eyes,135,139,Anatomy hyperplastic lesions,156,176,Anatomy CBE,184,187,Anatomy Fuchs ' s adenoma,190,207,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous identity, interaction with the surrounding stroma and tissues, hierarchic network formation, and recruitment of pericytes.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Vascular,0,8,Anatomy arterial,105,113,Anatomy venous,117,123,Anatomy stroma,167,173,Anatomy tissues,178,185,Anatomy hierarchic network,187,205,Anatomy pericytes,236,245,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous identity, interaction with the surrounding stroma and tissues, hierarchic network formation, and recruitment of pericytes.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Vascular,0,8,Anatomy arterial,105,113,Anatomy venous,117,123,Anatomy stroma,167,173,Anatomy tissues,178,185,Anatomy hierarchic network,187,205,Anatomy pericytes,236,245,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Acquired molecular abnormalities (mutations or chromosomal translocations) of the RUNX1 transcription factor gene are frequent in acute myeloblastic leukemias (AMLs) and in therapy-related myelodysplastic syndromes, but rarely in acute lymphoblastic leukemias (ALLs) and chronic myelogenous leukemias (CMLs).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: chromosomal,48,59,Anatomy acute myeloblastic leukemias,131,159,Anatomy AMLs,162,166,Anatomy acute lymphoblastic leukemias,234,263,Anatomy ALLs,266,270,Anatomy chronic myelogenous leukemias,276,305,Anatomy CMLs,308,312,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Acquired molecular abnormalities (mutations or chromosomal translocations) of the RUNX1 transcription factor gene are frequent in acute myeloblastic leukemias (AMLs) and in therapy-related myelodysplastic syndromes, but rarely in acute lymphoblastic leukemias (ALLs) and chronic myelogenous leukemias (CMLs).. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: chromosomal,48,59,Anatomy acute myeloblastic leukemias,131,159,Anatomy AMLs,162,166,Anatomy acute lymphoblastic leukemias,234,263,Anatomy ALLs,266,270,Anatomy chronic myelogenous leukemias,276,305,Anatomy CMLs,308,312,Anatomy	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: Opinions on 3 areas were sought: pulp therapy for cariously involved primary teeth; indirect pulp treatment (IPT) for cariously involved immature permanent teeth; and innovative treatment options including pulpal revascularization and regeneration.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: pulp,33,37,Anatomy cariously,50,59,Anatomy teeth,77,82,Anatomy pulp,93,97,Anatomy cariously,119,128,Anatomy teeth,157,162,Anatomy pulpal,207,213,Anatomy	Task: Please carry out the named entity recognition task for the the text below. Text: Opinions on 3 areas were sought: pulp therapy for cariously involved primary teeth; indirect pulp treatment (IPT) for cariously involved immature permanent teeth; and innovative treatment options including pulpal revascularization and regeneration.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: pulp,33,37,Anatomy cariously,50,59,Anatomy teeth,77,82,Anatomy pulp,93,97,Anatomy cariously,119,128,Anatomy teeth,157,162,Anatomy pulpal,207,213,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: METHOD: Wild-type and phosphatase-inactive (C124A) PTEN plasmids were transfected into ovarian epithelial cancer A2780 cells, and their effects on cell apoptosis, cell proliferation, cell migration and cell invasion were analyzed by flow cytometry analysis, TUNEL assay, MTT assay, wound-healing assay and transwell assay.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: plasmids,61,69,Anatomy ovarian epithelial cancer A2780 cells,92,129,Anatomy cell,152,156,Anatomy cell,168,172,Anatomy cell,188,192,Anatomy cell,207,211,Anatomy wound,287,292,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: METHOD: Wild-type and phosphatase-inactive (C124A) PTEN plasmids were transfected into ovarian epithelial cancer A2780 cells, and their effects on cell apoptosis, cell proliferation, cell migration and cell invasion were analyzed by flow cytometry analysis, TUNEL assay, MTT assay, wound-healing assay and transwell assay.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: plasmids,61,69,Anatomy ovarian epithelial cancer A2780 cells,92,129,Anatomy cell,152,156,Anatomy cell,168,172,Anatomy cell,188,192,Anatomy cell,207,211,Anatomy wound,287,292,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To identify a suitable donor cell population for gene therapy applications to the central nervous system, primary fibroblasts isolated from skin biopsies and maintained in culture are employed as autologous cells for intracerebral grafting within the adult rat striatum.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: donor cell population,23,44,Anatomy central nervous system,82,104,Anatomy fibroblasts,114,125,Anatomy skin biopsies,140,153,Anatomy cells,207,212,Anatomy intracerebral,217,230,Anatomy striatum,261,269,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: To identify a suitable donor cell population for gene therapy applications to the central nervous system, primary fibroblasts isolated from skin biopsies and maintained in culture are employed as autologous cells for intracerebral grafting within the adult rat striatum.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: donor cell population,23,44,Anatomy central nervous system,82,104,Anatomy fibroblasts,114,125,Anatomy skin biopsies,140,153,Anatomy cells,207,212,Anatomy intracerebral,217,230,Anatomy striatum,261,269,Anatomy	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The angiogenic potency of adipose tissue was not related to its localization (with an angiogenic stimulation in 60% of SAT samples and 61% of VAT samples) or to adipocyte size or inflammatory infiltrate assessed in adipose samples before the graft on CAM.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: adipose tissue,26,40,Anatomy SAT samples,120,131,Anatomy VAT samples,143,154,Anatomy adipocyte,162,171,Anatomy adipose samples,216,231,Anatomy graft,243,248,Anatomy CAM,252,255,Anatomy	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The angiogenic potency of adipose tissue was not related to its localization (with an angiogenic stimulation in 60% of SAT samples and 61% of VAT samples) or to adipocyte size or inflammatory infiltrate assessed in adipose samples before the graft on CAM.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: adipose tissue,26,40,Anatomy SAT samples,120,131,Anatomy VAT samples,143,154,Anatomy adipocyte,162,171,Anatomy adipose samples,216,231,Anatomy graft,243,248,Anatomy CAM,252,255,Anatomy	[]	null
Task: Please carry out the NER task for the the text below. Text: SREBP activation decreased as ECs migration slowed; (2) Coincidental with SREBP activation, mRNA expression of its target genes such as low density lipoprotein receptor, HMG-CoA reductase, and fatty acid synthase also increased in migrating ECs population as detected by real-time PCR; (3) Migration induced SREBP activation in ECs was inhibited by SREBP-acting protein RNAi and pharmacologically by 25-hydroxycholesterol; (4) Inhibition of SREBP led to decreased ECs migration in various models; (5) Cells genetically deficient in SREBP-acting protein, S1P, or S2P, phenotypically exhibited impaired migration; (6) SREBP inhibition in ECs suppressed the activity of small GTPase Cdc42, a key molecule for ECs motility.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ECs,30,33,Anatomy ECs,244,247,Anatomy ECs,334,337,Anatomy ECs,475,478,Anatomy Cells,513,518,Anatomy ECs,651,654,Anatomy ECs,721,724,Anatomy	Task: Please carry out the NER task for the the text below. Text: SREBP activation decreased as ECs migration slowed; (2) Coincidental with SREBP activation, mRNA expression of its target genes such as low density lipoprotein receptor, HMG-CoA reductase, and fatty acid synthase also increased in migrating ECs population as detected by real-time PCR; (3) Migration induced SREBP activation in ECs was inhibited by SREBP-acting protein RNAi and pharmacologically by 25-hydroxycholesterol; (4) Inhibition of SREBP led to decreased ECs migration in various models; (5) Cells genetically deficient in SREBP-acting protein, S1P, or S2P, phenotypically exhibited impaired migration; (6) SREBP inhibition in ECs suppressed the activity of small GTPase Cdc42, a key molecule for ECs motility.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ECs,30,33,Anatomy ECs,244,247,Anatomy ECs,334,337,Anatomy ECs,475,478,Anatomy Cells,513,518,Anatomy ECs,651,654,Anatomy ECs,721,724,Anatomy	[]	null
Task: Please carry out the NER task for the the text below. Text: Based on our results, we hypothesize that FGFR2 (+)-TFs might provide cancer cells with a suitable microenvironment via secretion of proteins that could promote cancer development and progression through stimulation of cancer cell proliferation, induction of angiogenesis, inhibition of cell adhesion, enhancement of cell mobility, and promotion of the epithelial-mesenchymal transition.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cancer cells,73,85,Anatomy cancer,164,170,Anatomy cancer cell,222,233,Anatomy cell,290,294,Anatomy cell,320,324,Anatomy epithelial,356,366,Anatomy mesenchymal,369,380,Anatomy	Task: Please carry out the NER task for the the text below. Text: Based on our results, we hypothesize that FGFR2 (+)-TFs might provide cancer cells with a suitable microenvironment via secretion of proteins that could promote cancer development and progression through stimulation of cancer cell proliferation, induction of angiogenesis, inhibition of cell adhesion, enhancement of cell mobility, and promotion of the epithelial-mesenchymal transition.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: cancer cells,73,85,Anatomy cancer,164,170,Anatomy cancer cell,222,233,Anatomy cell,290,294,Anatomy cell,320,324,Anatomy epithelial,356,366,Anatomy mesenchymal,369,380,Anatomy	[]	null
Task: Please carry out the NER task for the the text below. Text: In similar transient transfection experiments in HeLa cells, overexpression of the wt human retinoblastoma susceptibility gene product, RB, was found to repress the serum-induced IL-6 (-225 to+ 13), c-fos (-711 to+ 42), and beta-actin (-3400 to+ 912) promoters but not the PRV-induced IL-6 (-110 to+ 13) or the serum-induced MHC (-528 to-38) promoters.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: wt human retinoblastoma susceptibility gene product,83,134,Gene/Protein RB,136,138,Gene/Protein IL - 6,181,187,Gene/Protein c - fos,206,213,Gene/Protein beta - actin,236,248,Gene/Protein IL - 6,304,310,Gene/Protein MHC,351,354,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: In similar transient transfection experiments in HeLa cells, overexpression of the wt human retinoblastoma susceptibility gene product, RB, was found to repress the serum-induced IL-6 (-225 to+ 13), c-fos (-711 to+ 42), and beta-actin (-3400 to+ 912) promoters but not the PRV-induced IL-6 (-110 to+ 13) or the serum-induced MHC (-528 to-38) promoters.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: wt human retinoblastoma susceptibility gene product,83,134,Gene/Protein RB,136,138,Gene/Protein IL - 6,181,187,Gene/Protein c - fos,206,213,Gene/Protein beta - actin,236,248,Gene/Protein IL - 6,304,310,Gene/Protein MHC,351,354,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The effect of Rho on AP-1 is independent of the mitogen-activated protein kinase pathway, as a dominant-negative MEK and a MEK inhibitor (PD98059) did not affect Rho-induced AP-1 activity.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Rho,14,17,Gene/Protein AP - 1,21,27,Gene/Protein mitogen - activated protein kinase,50,84,Gene/Protein dominant - negative MEK,99,122,Gene/Protein MEK,129,132,Gene/Protein Rho,169,172,Gene/Protein AP - 1,183,189,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: The effect of Rho on AP-1 is independent of the mitogen-activated protein kinase pathway, as a dominant-negative MEK and a MEK inhibitor (PD98059) did not affect Rho-induced AP-1 activity.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Rho,14,17,Gene/Protein AP - 1,21,27,Gene/Protein mitogen - activated protein kinase,50,84,Gene/Protein dominant - negative MEK,99,122,Gene/Protein MEK,129,132,Gene/Protein Rho,169,172,Gene/Protein AP - 1,183,189,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Experiments with epitope-tagged proteins show that UEV1A is a nuclear protein, whereas both Kua and Kua-UEV localize to cytoplasmic structures, indicating that the Kua domain determines the cytoplasmic localization of Kua-UEV.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: UEV1A,53,58,Gene/Protein Kua,94,97,Gene/Protein Kua,102,105,Gene/Protein UEV,108,111,Gene/Protein Kua domain,168,178,Gene/Protein Kua,222,225,Gene/Protein UEV,228,231,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Experiments with epitope-tagged proteins show that UEV1A is a nuclear protein, whereas both Kua and Kua-UEV localize to cytoplasmic structures, indicating that the Kua domain determines the cytoplasmic localization of Kua-UEV.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: UEV1A,53,58,Gene/Protein Kua,94,97,Gene/Protein Kua,102,105,Gene/Protein UEV,108,111,Gene/Protein Kua domain,168,178,Gene/Protein Kua,222,225,Gene/Protein UEV,228,231,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: However, five new mutation sites (S61, SL1, S29, SL11, SL196 and SL126) are unique to the nrdB intron and disrupt self-splicing.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: S61,35,38,Gene/Protein SL1,40,43,Gene/Protein S29,45,48,Gene/Protein SL11,50,54,Gene/Protein SL196,56,61,Gene/Protein SL126,66,71,Gene/Protein nrdB,91,95,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: However, five new mutation sites (S61, SL1, S29, SL11, SL196 and SL126) are unique to the nrdB intron and disrupt self-splicing.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: S61,35,38,Gene/Protein SL1,40,43,Gene/Protein S29,45,48,Gene/Protein SL11,50,54,Gene/Protein SL196,56,61,Gene/Protein SL126,66,71,Gene/Protein nrdB,91,95,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: The amino-terminal DNA-binding domain of Pip exhibits a high degree of homology to the DNA-binding domains of members of the interferon regulatory factor (IRF) family, which includes IRF-1, IRF-2, ICSBP, and ISGF3 gamma.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Pip,45,48,Gene/Protein interferon regulatory factor,131,159,Gene/Protein IRF,162,165,Gene/Protein IRF - 1,190,197,Gene/Protein IRF - 2,199,206,Gene/Protein ICSBP,208,213,Gene/Protein ISGF3 gamma,219,230,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: The amino-terminal DNA-binding domain of Pip exhibits a high degree of homology to the DNA-binding domains of members of the interferon regulatory factor (IRF) family, which includes IRF-1, IRF-2, ICSBP, and ISGF3 gamma.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Pip,45,48,Gene/Protein interferon regulatory factor,131,159,Gene/Protein IRF,162,165,Gene/Protein IRF - 1,190,197,Gene/Protein IRF - 2,199,206,Gene/Protein ICSBP,208,213,Gene/Protein ISGF3 gamma,219,230,Gene/Protein	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: The SCMV SNE sites contain potential overlapping core recognition binding motifs for SRF, Rel/NFkappaB, ETS, and YY1 class transcription factors but fail to respond to either serum or tumor necrosis factor alpha.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: SCMV SNE sites,4,18,Gene/Protein SRF,85,88,Gene/Protein Rel,90,93,Gene/Protein NFkappaB,96,104,Gene/Protein ETS,106,109,Gene/Protein YY1 class transcription factors,115,146,Gene/Protein tumor necrosis factor alpha,186,213,Gene/Protein	Task: Please carry out the named entity recognition task for the the text below. Text: The SCMV SNE sites contain potential overlapping core recognition binding motifs for SRF, Rel/NFkappaB, ETS, and YY1 class transcription factors but fail to respond to either serum or tumor necrosis factor alpha.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: SCMV SNE sites,4,18,Gene/Protein SRF,85,88,Gene/Protein Rel,90,93,Gene/Protein NFkappaB,96,104,Gene/Protein ETS,106,109,Gene/Protein YY1 class transcription factors,115,146,Gene/Protein tumor necrosis factor alpha,186,213,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Amplification and overexpression of the c-erbB-2 gene in 21MT-2 and 21MT-1 human breast carcinoma cells results in progressively elevated levels of constitutively tyrosine-phosphorylated p185erbB-2 and is associated with progressive insulin-like growth factor (IGF) and combined IGF/epidermal growth factor (EGF) independence in culture.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: c - erbB - 2 gene,40,57,Gene/Protein tyrosine - phosphorylated p185erbB - 2,171,209,Gene/Protein insulin - like growth factor,245,273,Gene/Protein IGF,276,279,Gene/Protein IGF,294,297,Gene/Protein epidermal growth factor,300,323,Gene/Protein EGF,326,329,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Amplification and overexpression of the c-erbB-2 gene in 21MT-2 and 21MT-1 human breast carcinoma cells results in progressively elevated levels of constitutively tyrosine-phosphorylated p185erbB-2 and is associated with progressive insulin-like growth factor (IGF) and combined IGF/epidermal growth factor (EGF) independence in culture.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: c - erbB - 2 gene,40,57,Gene/Protein tyrosine - phosphorylated p185erbB - 2,171,209,Gene/Protein insulin - like growth factor,245,273,Gene/Protein IGF,276,279,Gene/Protein IGF,294,297,Gene/Protein epidermal growth factor,300,323,Gene/Protein EGF,326,329,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In addition to targeting partially assembled Ti alpha-beta CD3 gamma delta epsilon TCR complexes to the cell surface, CD3 zeta appears to be essential for interleukin-2 production after TCR stimulation with antigen/major histocompatibility complex.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Ti alpha - beta,45,60,Gene/Protein CD3 gamma delta epsilon,61,84,Gene/Protein TCR complexes,85,98,Gene/Protein CD3 zeta,120,128,Gene/Protein interleukin - 2,157,172,Gene/Protein TCR,190,193,Gene/Protein antigen / major histocompatibility complex,211,253,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: In addition to targeting partially assembled Ti alpha-beta CD3 gamma delta epsilon TCR complexes to the cell surface, CD3 zeta appears to be essential for interleukin-2 production after TCR stimulation with antigen/major histocompatibility complex.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: Ti alpha - beta,45,60,Gene/Protein CD3 gamma delta epsilon,61,84,Gene/Protein TCR complexes,85,98,Gene/Protein CD3 zeta,120,128,Gene/Protein interleukin - 2,157,172,Gene/Protein TCR,190,193,Gene/Protein antigen / major histocompatibility complex,211,253,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: RAS2val19, a dominant activated form of Saccharomyces cerevisiae Ras2, stimulates both filamentous growth and expression of a transcriptional reporter FG (TyA):: lacZ but does not induce the mating pathway reporter FUS1:: lacZ.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: RAS2val19,0,9,Gene/Protein Saccharomyces cerevisiae Ras2,40,69,Gene/Protein FG,151,153,Gene/Protein TyA,156,159,Gene/Protein lacZ,163,167,Gene/Protein mating pathway reporter FUS1,192,220,Gene/Protein lacZ,223,227,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: RAS2val19, a dominant activated form of Saccharomyces cerevisiae Ras2, stimulates both filamentous growth and expression of a transcriptional reporter FG (TyA):: lacZ but does not induce the mating pathway reporter FUS1:: lacZ.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: RAS2val19,0,9,Gene/Protein Saccharomyces cerevisiae Ras2,40,69,Gene/Protein FG,151,153,Gene/Protein TyA,156,159,Gene/Protein lacZ,163,167,Gene/Protein mating pathway reporter FUS1,192,220,Gene/Protein lacZ,223,227,Gene/Protein	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: The deduced bovine EFIA # 1 amino acid (aa) sequence is 98% identical to rat EFIA and 100% identical to human EFIA/DbpB/YB-1 family member DNA-binding protein B (DbpB).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: EFIA # 1,19,27,Gene/Protein EFIA,78,82,Gene/Protein EFIA,111,115,Gene/Protein DbpB,118,122,Gene/Protein YB - 1,125,131,Gene/Protein DNA - binding protein B,146,169,Gene/Protein DbpB,172,176,Gene/Protein	Task: Please carry out the named entity recognition task for the the text below. Text: The deduced bovine EFIA # 1 amino acid (aa) sequence is 98% identical to rat EFIA and 100% identical to human EFIA/DbpB/YB-1 family member DNA-binding protein B (DbpB).. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: EFIA # 1,19,27,Gene/Protein EFIA,78,82,Gene/Protein EFIA,111,115,Gene/Protein DbpB,118,122,Gene/Protein YB - 1,125,131,Gene/Protein DNA - binding protein B,146,169,Gene/Protein DbpB,172,176,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Similarly, the DNA-binding activity of activator protein 1 (AP-1) is modified by a DNA repair enzyme, redox factor 1 (Ref-1), which is identical to a DNA repair enzyme, AP endonuclease.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: activator protein 1,41,60,Gene/Protein AP - 1,63,69,Gene/Protein DNA repair enzyme,88,105,Gene/Protein redox factor 1,107,121,Gene/Protein Ref - 1,124,131,Gene/Protein DNA repair enzyme,158,175,Gene/Protein AP endonuclease,177,192,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: Similarly, the DNA-binding activity of activator protein 1 (AP-1) is modified by a DNA repair enzyme, redox factor 1 (Ref-1), which is identical to a DNA repair enzyme, AP endonuclease.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: activator protein 1,41,60,Gene/Protein AP - 1,63,69,Gene/Protein DNA repair enzyme,88,105,Gene/Protein redox factor 1,107,121,Gene/Protein Ref - 1,124,131,Gene/Protein DNA repair enzyme,158,175,Gene/Protein AP endonuclease,177,192,Gene/Protein	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: However, mutations in the HNF-4 binding site on element CIIB and inhibition of HNF-4 synthesis in HepG2 cells by antisense HNF-4 constructs decreased the apoCII promoter activity to 25-40% of the control, indicating that HNF-4 is a positive regulator of the apoCII gene.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: HNF - 4 binding site,26,46,Gene/Protein element CIIB,50,62,Gene/Protein HNF - 4,81,88,Gene/Protein HNF - 4 constructs,127,145,Gene/Protein apoCII promoter,160,175,Gene/Protein HNF - 4,229,236,Gene/Protein apoCII gene,268,279,Gene/Protein	Task: Please carry out the named entity recognition task for the the text below. Text: However, mutations in the HNF-4 binding site on element CIIB and inhibition of HNF-4 synthesis in HepG2 cells by antisense HNF-4 constructs decreased the apoCII promoter activity to 25-40% of the control, indicating that HNF-4 is a positive regulator of the apoCII gene.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: HNF - 4 binding site,26,46,Gene/Protein element CIIB,50,62,Gene/Protein HNF - 4,81,88,Gene/Protein HNF - 4 constructs,127,145,Gene/Protein apoCII promoter,160,175,Gene/Protein HNF - 4,229,236,Gene/Protein apoCII gene,268,279,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: TCR alpha and beta gene expression may be regulated by a common set of T-cell nuclear proteins in that the T beta 2 element binding a set of cyclic AMP response element-binding proteins that are also bound by the T alpha 1 element of the human TCR alpha enhancer and the decamer element present in a large number of human and murine TCR beta promoters.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: TCR alpha and beta gene,0,23,Gene/Protein T - cell nuclear proteins,71,96,Gene/Protein T beta 2 element,109,125,Gene/Protein cyclic AMP response element - binding proteins,143,189,Gene/Protein T alpha 1 element,217,234,Gene/Protein TCR alpha,248,257,Gene/Protein TCR beta,337,345,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: TCR alpha and beta gene expression may be regulated by a common set of T-cell nuclear proteins in that the T beta 2 element binding a set of cyclic AMP response element-binding proteins that are also bound by the T alpha 1 element of the human TCR alpha enhancer and the decamer element present in a large number of human and murine TCR beta promoters.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: TCR alpha and beta gene,0,23,Gene/Protein T - cell nuclear proteins,71,96,Gene/Protein T beta 2 element,109,125,Gene/Protein cyclic AMP response element - binding proteins,143,189,Gene/Protein T alpha 1 element,217,234,Gene/Protein TCR alpha,248,257,Gene/Protein TCR beta,337,345,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: When the 73-bp fragment was fused to an alpha1-globin promoter-CAT construct and cotransfected with CCAAT transcription factor 1 (CTF1) / NF1 into Drosophila Schneider SL2 insect cells (which lack NF1-like proteins) trans-activation of CAT activity was observed.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: alpha1 - globin,42,57,Gene/Protein CAT,69,72,Gene/Protein CCAAT transcription factor 1,106,134,Gene/Protein CTF1,137,141,Gene/Protein NF1,145,148,Gene/Protein NF1 - like proteins,205,224,Gene/Protein CAT,248,251,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: When the 73-bp fragment was fused to an alpha1-globin promoter-CAT construct and cotransfected with CCAAT transcription factor 1 (CTF1) / NF1 into Drosophila Schneider SL2 insect cells (which lack NF1-like proteins) trans-activation of CAT activity was observed.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: alpha1 - globin,42,57,Gene/Protein CAT,69,72,Gene/Protein CCAAT transcription factor 1,106,134,Gene/Protein CTF1,137,141,Gene/Protein NF1,145,148,Gene/Protein NF1 - like proteins,205,224,Gene/Protein CAT,248,251,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: Mutating the Fcp1p-binding motif KEFGK in the RAP74 (Tfg1p) subunit of TFIIF to EEFGE led to both synthetic phenotypes in certain fcp1 tfg1 double mutants and a reduced ability of Fcp1p to activate transcription when it is artificially tethered to a promoter.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Fcp1p,13,18,Gene/Protein RAP74,48,53,Gene/Protein Tfg1p,56,61,Gene/Protein TFIIF,74,79,Gene/Protein fcp1,133,137,Gene/Protein tfg1,138,142,Gene/Protein Fcp1p,183,188,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: Mutating the Fcp1p-binding motif KEFGK in the RAP74 (Tfg1p) subunit of TFIIF to EEFGE led to both synthetic phenotypes in certain fcp1 tfg1 double mutants and a reduced ability of Fcp1p to activate transcription when it is artificially tethered to a promoter.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: Fcp1p,13,18,Gene/Protein RAP74,48,53,Gene/Protein Tfg1p,56,61,Gene/Protein TFIIF,74,79,Gene/Protein fcp1,133,137,Gene/Protein tfg1,138,142,Gene/Protein Fcp1p,183,188,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: The 5 ' region of ADH5 contains consensus binding sites for the transcriptional regulatory proteins, Sp1, AP2, LF-A1, NF-1, NF-A2, and NF-E1.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ADH5,18,22,Gene/Protein Sp1,101,104,Gene/Protein AP2,106,109,Gene/Protein LF - A1,111,118,Gene/Protein NF - 1,120,126,Gene/Protein NF - A2,128,135,Gene/Protein NF - E1,141,148,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: The 5 ' region of ADH5 contains consensus binding sites for the transcriptional regulatory proteins, Sp1, AP2, LF-A1, NF-1, NF-A2, and NF-E1.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: ADH5,18,22,Gene/Protein Sp1,101,104,Gene/Protein AP2,106,109,Gene/Protein LF - A1,111,118,Gene/Protein NF - 1,120,126,Gene/Protein NF - A2,128,135,Gene/Protein NF - E1,141,148,Gene/Protein	[]	null
Task: Please carry out the named entity recognition task for the the text below. Text: The use of the PLCgamma inhibitory peptide, neomycin and the calcium chelator BAPTA-AM on oocytes expressing FGFR1 or the stimulation by PDGF-BB of oocytes expressing PDGFR-FGFR1 mutated on the PLCgamma binding site, prevented GVBD and ERK2 phosphorylation.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: PLCgamma inhibitory peptide,15,42,Gene/Protein FGFR1,111,116,Gene/Protein PDGF - BB,139,148,Gene/Protein PDGFR,171,176,Gene/Protein FGFR1,179,184,Gene/Protein PLCgamma binding site,200,221,Gene/Protein ERK2,242,246,Gene/Protein	Task: Please carry out the named entity recognition task for the the text below. Text: The use of the PLCgamma inhibitory peptide, neomycin and the calcium chelator BAPTA-AM on oocytes expressing FGFR1 or the stimulation by PDGF-BB of oocytes expressing PDGFR-FGFR1 mutated on the PLCgamma binding site, prevented GVBD and ERK2 phosphorylation.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type in separate lines with a high probability of being in the text. Result: PLCgamma inhibitory peptide,15,42,Gene/Protein FGFR1,111,116,Gene/Protein PDGF - BB,139,148,Gene/Protein PDGFR,171,176,Gene/Protein FGFR1,179,184,Gene/Protein PLCgamma binding site,200,221,Gene/Protein ERK2,242,246,Gene/Protein	[]	null
Task: Please carry out the NER task for the the text below. Text: MEF and AML1B synergistically transactivated an interleukin 3 promoter reporter gene construct, yet the activating activity of MEF was abolished when MEF was coexpressed with AML1/ETO.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: MEF,0,3,Gene/Protein AML1B,8,13,Gene/Protein interleukin 3 promoter reporter gene construct,48,94,Gene/Protein MEF,127,130,Gene/Protein MEF,150,153,Gene/Protein AML1,175,179,Gene/Protein ETO,182,185,Gene/Protein	Task: Please carry out the NER task for the the text below. Text: MEF and AML1B synergistically transactivated an interleukin 3 promoter reporter gene construct, yet the activating activity of MEF was abolished when MEF was coexpressed with AML1/ETO.. Constrain: Please, list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: MEF,0,3,Gene/Protein AML1B,8,13,Gene/Protein interleukin 3 promoter reporter gene construct,48,94,Gene/Protein MEF,127,130,Gene/Protein MEF,150,153,Gene/Protein AML1,175,179,Gene/Protein ETO,182,185,Gene/Protein	[]	null
Task: Please carry out the named entity recognition (NER) task for the the text below. Text: First, a pet54:: LEU2 cytoductant bearing the'short'mitochondrial genome that lacks both COX1 introns aI5 alpha and aI5 beta is defective only in COX3 gene expression and not in COX1 mRNA splicing or mRNA translation.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pet54,9,14,Gene/Protein LEU2,17,21,Gene/Protein COX1 introns,93,105,Gene/Protein aI5 alpha,106,115,Gene/Protein aI5 beta,120,128,Gene/Protein COX3 gene,150,159,Gene/Protein COX1 mRNA,182,191,Gene/Protein	Task: Please carry out the named entity recognition (NER) task for the the text below. Text: First, a pet54:: LEU2 cytoductant bearing the'short'mitochondrial genome that lacks both COX1 introns aI5 alpha and aI5 beta is defective only in COX3 gene expression and not in COX1 mRNA splicing or mRNA translation.. Constrain: Please, only list the entities in the form NER entity, span start, span end, and type with a high probability of being in the text. Result: pet54,9,14,Gene/Protein LEU2,17,21,Gene/Protein COX1 introns,93,105,Gene/Protein aI5 alpha,106,115,Gene/Protein aI5 beta,120,128,Gene/Protein COX3 gene,150,159,Gene/Protein COX1 mRNA,182,191,Gene/Protein	[]	null