instruction
stringlengths 9
11.7k
| context
stringlengths 0
16.8k
| response
stringlengths 1
8.88k
| category
stringclasses 3
values | __index_level_0__
int64 0
15k
|
|---|---|---|---|---|
Based on the paragraph below, what bone was used to estimate the height of William the Conquerer?
|
No authentic portrait of William has been found; the contemporary depictions of him on the Bayeux Tapestry and on his seals and coins are conventional representations designed to assert his authority. There are some written descriptions of a burly and robust appearance, with a guttural voice. He enjoyed excellent health until old age, although he became quite fat in later life. He was strong enough to draw bows that others were unable to pull and had great stamina. Geoffrey Martel described him as without equal as a fighter and as a horseman. Examination of William's femur, the only bone to survive when the rest of his remains were destroyed, showed he was approximately 5 feet 10 inches (1.78 m) in height.
|
His femur.
|
closed_qa
| 7,672 |
Who wrote Mahabharata?
|
According to ancient Indian tradition, Vyasa is the author of Mahabharata who is also a major character in the epic. It is first recited the sage Vaisampayana to the King Janamejaya who was the great-grandson of the Pandavas. The story is then recited again by a Ugrasrava Sauti to an assembly of sages in Naimisa forest.
|
open_qa
| 7,673 |
|
Is Microsoft a FAANG stock?
|
FAANG is an acronym that refers to the stocks of five hot new technology companies in the 2010s with huge potential growth. FAANG is made up of the first letter of each of these companies. They are Facebook (now Meta), Amazon, Apple, Netflix and Google (now Alphabet).
Microsoft is not part of this mix, as by the 2010s Microsoft was already a well established and mature company.
|
general_qa
| 7,674 |
|
What is Pythagorean or Pythagoras' Theorem
|
Pythoagorean theorem is an euclidian theorem attributed to a Greek philosopher from around 570 BC named Pythagoras.
The Pythagorean theorem states that for a right angled triangle, the sum of the squares of the two adjacent sides is equal to the square of the hypotenuse (the side opposite to the right angeled triangle).
|
general_qa
| 7,675 |
|
Where is the best place to work in my house?
|
If you are working from home full time you will want make sure you pick the best area in your house to work that offers you a quiet space where you can focus for work. Pick an area that is not busy like your master bedroom or separate bedroom that no one uses that can be used as an office. You will want to make sure this space has a door so you can prevent outside noise from being a distraction. This space will need a desk that you can work at, and you might want to consider a sit-stand desk so you can can keep good blood in your body flow throughout the day. Sitting all day restricts blood flow and actually inhibits your ability to produce work results at your best so get something that prevents this.
|
open_qa
| 7,677 |
|
Name five MLB teams in the American League.
|
Five MLB teams in the American League are the Tampa Rays, Boston Red Sox, Kansas City Royals, Texas Rangers, and Seattle Mariners.
|
open_qa
| 7,678 |
|
Which year was quantum computer demonstrated to be possible?
|
Over the years, experimentalists have constructed small-scale quantum computers using trapped ions and superconductors. In 1998, a two-qubit quantum computer demonstrated the feasibility of the technology, and subsequent experiments have increased the number of qubits and reduced error rates. In 2019, Google AI and NASA announced that they had achieved quantum supremacy with a 54-qubit machine, performing a computation that is impossible for any classical computer. However, the validity of this claim is still being actively researched.
|
1998
|
closed_qa
| 7,681 |
What do you think a conversation between two AI bots would look like?
|
I do not know but I would like to imagine the two bots are both trained on enormous corpse of data available online. If the datasets are different, the conversation could go very interesting and unexpected for humans ways. The common ML algorithms might be similar or shared so I wonder if the reasoning behind the bots will be similar and a pattern could be drawn on them.
|
general_qa
| 7,684 |
|
How much PVC produced each year?
|
Polyvinyl chloride (alternatively: poly(vinyl chloride), colloquial: polyvinyl, or simply vinyl; abbreviated: PVC) is the world's third-most widely produced synthetic polymer of plastic (after polyethylene and polypropylene). About 40 million tons of PVC are produced each year.
|
Each year about 40 million tons of PVC are produced.
|
closed_qa
| 7,686 |
What age would a child become a tween?
|
Generally a tween is in between their child years and teenage years, between the ages of10 and 13.
|
open_qa
| 7,688 |
|
is finance a great career
|
yes
|
open_qa
| 7,689 |
|
What are Roland's most famous synthesizers and drum machines from the 1980s and what do they do?
|
The most famous Roland synthesizer and drum machines from the 1980s are the Roland TB-303, TR-606, TR-808, and TR-909. Although all were generally commercial failures at first, the TB-303 Bass Line became widely used in techno because of its distinctive resonant filter, beginning with Phuture's "Acid Tracks". The TR-606 Drumatix was also later widely used in electronica. However the TR-808 Rhythm Composer's booming kick and snare sound were even more popular, appearing widely in hip-hop tracks. The TR-909 was and is widely used in dance and pop music, known for its signature snare and hi hat cymbal sounds.
|
general_qa
| 7,690 |
|
What is the main tax-related difference between a brokerage account and an IRA ?
|
The main difference tax-related difference between a brokerage account and an IRA is that the gains made on investments in a brokerage account are subject to capital gains taxes while gains in an IRA are not.
|
open_qa
| 7,691 |
|
What is the GE Dash 8-32BWH
|
The GE Dash 8-32BWH, also known as the P32-8BWH, B32-8WH, or P32-8, is a passenger train locomotive used by Amtrak, based on GE's Dash 8 series of freight train locomotives. Built in 1991, they were the first locomotives purchased to replace the EMD F40PH.
|
open_qa
| 7,693 |
|
What is the difference between coalesce and repartition when it comes to shuffle partitions in spark
|
Coalesce essentially groups multiple partitions into a larger partitions. So use coalesce when you want to reduce the number of partitions (and also tasks) without impacting sort order. Ex:- when you want to write-out a single CSV file output instead of multiple parts
Use repartition when you want to cause a shuffle that changes the number of partitions. A common use-case for repartition is to remove skew in file sizes or to start out with a smaller/different number of partitions than the default in Spark
|
general_qa
| 7,697 |
|
How do UK telephone numbers work?
|
The UK telephone numbering system has a strange and complicated pattern which is born out of many historical changes and anomalies. Essentially nearly all numbers start with 0 when dialled in the UK. The leading 0 is omitted when calling from overseas and the prefix "+44" is added in its place. The second digit indicates what type of number it is. So called geographic numbers (those associated with an area code) start with 01or 02. Numbers starting with 03 are not associated with any area code but are charged at the same rates as numbers beginning with 01 or 02. Mobile numbers always start with 07. Numbers starting 09 are premium rate numbers which incur high charges for providing additional services. Numbers starting with 080 are toll free. Other numbers starting with 08 are charged at special rates but not the very high rates for 09 numbers.
Special numbers that do not start with 0 include 999 and 112 for emergencies, 101 for non emergency Police matters, 111 for contacting the National Health Service in a non emergency and directory enquiries services that start with 118.
The history of UK area codes (beginning 01 and 02) dates back to the times when individual telephone exchanges had their own one, two or three character Subscriber Trunk Dialing (STD) codes (e.g. B for Birmingham or AY6 for Aylesbury). in 1966 STD codes were converted to numbers using the number patterns on telephone dials (where 2=ABC, 3 = DEF etc.) so Birmingham became 021, Aylesbury became 0296. 01 was the code allocated to London. Area codes were between 2 and five characters long including the leading zero. Following the area code a local number of between 3 and 7 digits was added for each line to make the complete number either 9 or 10 digits long. Callers within the same area code could dial other lines with the same code by simply dialling the local number omitting the area code. In 1968 area codes beginning 00 were moved to free up 00 for other uses.
By the 1980s a number of factors meant that some areas, especially London, were running out of codes. Various measures were introduced including, in 1990, the splitting of London into 071 (inner London) and 081 (outer London).
The 80s and 90s also saw the gradual introduction of "non geographic" numbers e.g. the toll free 0800 numbers and a number of patterns for emerging mobile services. Premium rate services were also launched using 0898.
In 1995 on so called "phONEday" a leading 1 was added after the zero. London numbers became either 0171 or 0181, Birmingham 0121, Aylesbury 01296 etc.
This established the pattern we see today allowing for some area codes to move to "02" codes over the next few years. In addition larger cities were allocated new codes beginning 011 e.g. 0113 for Leeds, 0117 for Bristol.
In 2000 the "big number change" saw London codes changed yet again = 0171 became 020 7 and 0181 became 020 8 allowing for new London numbers to be issued starting with 020 3 and 020 4 . Other cities that gained "02" style codes were Southampton/Portsmouth 023 , Coventry 024 and Cardiff 029. A unified code of 028 was introduced in Northern Ireland.
|
general_qa
| 7,699 |
|
What does WHO refer to?
|
WHO is an acronym for the World Health Organization.
|
open_qa
| 7,700 |
|
Given this paragraph about Dill Records, tell me when the group made CDs and who started the record label.
|
Dill Records was a small punk rock/ska record label based out of Monte Sereno, California, that put out CDs/records from 1989-1998. The name is an allusion to initially the label's only band, Skankin' Pickle. The record label was started by Mike Park, a.k.a. Bruce Lee of Skankin' Pickle. The first other band with a release on Dill Records was the Tantra Monsters (Dill 006) in 1994. After the breakup of Skankin' Pickle, Mike Park continued releasing records, beginning the label Asian Man Records in 1996. Asian Man and Dill Records coexisted until 1998. Asian Man re-released many albums originally released by Dill Records, as all releases are now out of print and Dill Records is no longer in operation.
|
Dill Records was started by Mike Park and made CDs from 1989 to 1998.
|
closed_qa
| 7,701 |
What are the debt securities?
|
Debt securities are financial assets that define the terms of a loan between an issuer (the borrower) and an investor (the lender). The terms of a debt security typically include the principal amount to be returned upon maturity of the loan, interest rate payments, and the maturity date or renewal date.
|
open_qa
| 7,702 |
|
Can I learn to ski as an adult?
|
Yes. Alpine downhill skiing is a sport that can be learned at any age. While many learn to ski when they're young, there are lots of people that only started to ski at an older age. With the right motivation and a willingness to put time and effort, almost anyone can learn to ski. Also, advances to ski equipment and slope grooming technology make skiing a lot safer than it used to be years ago.
Learning to ski as an adult may take longer than learning as a child. It is recommended that you start with some lessons first to gain the right technique. This could be group lessons or private lessons. You could also learn from friends who know how to ski, or learn by watching online tutorials and applying them yourself on the mountain. Once you have the basic skills, you should be able to ski easy slopes and start enjoying skiing as a fun activity.
In addition to lessons, you will also need the right gear to ski. This includes appropriate clothing that can keep you warm on the mountain while you ski, as well as ski equipment that you will use. It is recommended that you get a pair of skis and poles, good fitting boots, a helmet for safety, and goggles to protect your eyes from the elements. Renting your equipment is a good option when you're starting. That way you are not making an expensive commitment upfront. You could also buy your equipment either new or from any of the second-hand ski shops and ski swaps.
With the right gear and knowledge of the basics, you can take your learning in any direction you want. Many people choose to stay at a beginner or intermediate level and just enjoy the occasional ski trip with friends. While others take their passion forward with more practice, hours on the mountain, and likely more lessons to get to advanced levels.
Whichever path you pick, skiing can be a fun sport to learn and enjoy for the rest of your life. Have fun skiing. You got this!
|
general_qa
| 7,703 |
|
Given a reference text, who is the Ryder Cup named after?
|
The Ryder Cup is a biennial men's golf competition between teams from Europe and the United States. The competition is contested every two years with the venue alternating between courses in the United States and Europe. The Ryder Cup is named after the English businessman Samuel Ryder who donated the trophy. The event is jointly administered by the PGA of America and Ryder Cup Europe, the latter a joint venture of the PGA European Tour (60%), the PGA of Great Britain and Ireland (20%), and the PGAs of Europe (20%).
Originally contested between Great Britain and the United States, the first official Ryder Cup took place in the United States in 1927 at Worcester Country Club in Worcester, Massachusetts. The home team won the first five contests, but with the competition's resumption after the Second World War, repeated American dominance eventually led to a decision to extend the representation of "Great Britain and Ireland" to include continental Europe from 1979. The inclusion of continental European golfers was partly prompted by the success of a new generation of Spanish golfers, led by Seve Ballesteros and Antonio Garrido. In 1973 the official title of the British Team had been changed from "Great Britain" to "Great Britain and Ireland", but this was simply a change of name to reflect the fact that golfers from the Republic of Ireland had been playing in the Great Britain Ryder Cup team since 1953, while Northern Irish players had competed since 1947. In addition to players from Great Britain and Ireland, the European team has since included players from Austria, Belgium, Denmark, France, Germany, Italy, Norway, Spain and Sweden.
|
The Ryder Cup is named after English businessman Samuel Ryder.
|
closed_qa
| 7,704 |
What makes airplanes fly?
|
When an airplane engine starts, the propeller creates thrust and pulls the airplane forward. As the airplane moves forward, more and more air moves over the wing. The airplane wings are designed to be curved over the top and flat across the bottom. As a result, the air molecules take longer to travel over the top of the wing than they do on the underside. This creates a differential in air pressure between the top and bottom of the wing. The difference in air pressure is called Lift. As thrust increases and pulls the plane forward, the lift eventually increases enough to overcome the weight and drag and the airplane will take flight.
|
general_qa
| 7,706 |
|
Who is John Melo
|
John Melo is a Filipino singer and songwriter. He won the 1993 Awit Awards for Best New Male Performance. After a long absence from the music scene, he returned in 2017 with his new song Malapit Na Ang Pasko. He is also a U.S Correspondent and a sports news writer
|
open_qa
| 7,707 |
|
What are red wigglers?
|
Their true name is eisenia fetida and is known as the most common compost worm. These worms are not found in the soil but rather live in the upper layers of organic matter.
The worms have gizzards like chickens. They are hermaphroditic which means they have move male and female sex organs. It takes two worms to produce a cocoon which could produce three worms each.
The worms produce vermicast (worm poop) which many organic famers use to add to their soil.
|
general_qa
| 7,709 |
|
Tell me about the play Die Schutzbefohlenen
|
Die Schutzbefohlenen (translated as "Charges (The Supplicants)"[note 1]), is a play by Elfriede Jelinek written in 2013. She termed it a Sprachkunstwerk, a language artwork. It deals critically with the politics at the time concerning refugees. The play was first read in Hamburg on 21 September 2013. The first scenic production was in Mannheim on 23 May 2014. The first production in Austria was staged at the Burgtheater in Vienna on 28 March 2015, which was recognised internationally. Later that year, Jelinek expanded the text to reflect the changed political situation.
|
Die Schutzbefohlenen, translated as the supplicants is a play by Elfriede Jelinek written in 2013. She termed it a Sprachkunstwerk, a language artwork. It deals critically with the politics at the time concerning refugees. The play was first read in Hamburg on 21 September 2013. The first scenic production was in Mannheim on 23 May 2014.
The first production in Austria was staged at the Burgtheater in Vienna on 28 March 2015, which was recognised internationally. Later that year, Jelinek expanded the text to reflect the changed political situation.
|
closed_qa
| 7,711 |
What age is considered legal adulthood in much of the western world?
|
18 years is typically when one is legally an adult
|
open_qa
| 7,715 |
|
What product do the Girl Scouts sell?
|
Girl Scouts sell cookies
|
open_qa
| 7,716 |
|
Tell me about the first commercial winery in California.
|
The first commercial winery in California was founded in 1857 by Hungarian-American Agoston Haraszthy who is referred to as the "Father of California Wine" (this moniker also is applied to Spanish Jesuit missionary, Father Junípero Serra).
Haraszthy opened Buena Vista Winery in Sonoma. By 1859, the winery was producing two million gallons of wine a year and one of its most popular products was sparkling wine.
The winery faced numerous troubles over the years, such as bankruptcy, a devastating infestation of Grape phylloxera, and Prohibition. The winery was acquired at auction and original vines replanted and reopened in the 1940s. In 1984, the winery estate expanded an additional 1,000 acres after it was purchased by a West German company. The winery continued to change hands and is now under the ownership of Jean-Charles Boisset, who operates over two dozen wineries under his wine group, Boisset Collection.
The winery still sits on its original location and has been added to the US National Register of Historic Places and the list of California Historical Landmarks.
|
open_qa
| 7,717 |
|
Which English football team have held the FA cup the longest?
|
Portsmouth have the distinction of being the football club which has held the FA Cup trophy for the longest uninterrupted period - seven years. Portsmouth had defeated Wolverhampton Wanderers 4–1 in the 1939 FA Cup Final and were awarded the trophy as 1938–39 FA Cup winners. But with the outbreak of World War II in September 1939, the regular Football League and FA Cup competitions for the 1939–40 season were cancelled for the duration of the war. Portsmouth's manager Jack Tinn was rumoured to have kept the FA Cup trophy 'safe under his bed' throughout the duration of the war, but this is an urban myth. Because the naval city of Portsmouth was a primary strategic military target for German Luftwaffe bombing, the FA Cup trophy was actually taken ten miles to the north of Portsmouth, to the nearby Hampshire village of Lovedean, and there it resided in a quaint thatched roof country pub called The Bird in Hand for the seven years of the war. After the conclusion of World War II, the FA Cup trophy was presented back to the Football Association by the club in time for the 1946 FA Cup Final.
|
Portsmouth FC
|
closed_qa
| 7,718 |
What is the relationship between interest rates and the economy?
|
Central banks typically adjust interest rates as a way to influence inflation and economic growth. When a country is experiencing high rates of inflation, its central bank will typically increase the interest rate which will increase the cost of credit and therefore reduce economic demand and consumption. Reduced demand will lead to reduced prices and less inflation. When a country is experiencing deflation, the central bank will typically decrease interest rates to reduce cost of credit and increase consumption. Central banks must be careful with interest rates. High interest rates for a sustained period of time can lead to a recession. Whereas, low interest rates for a sustained period of time can lead to hyperinflation and an overheated economy.
|
open_qa
| 7,719 |
|
What countries have won the ODI Cricket World Cup?
|
Australia, England, India, Sri Lanka, Pakistan
|
open_qa
| 7,723 |
|
Based on this passage, how many Boeing 747s are required to ship 10 of ASML's best-selling EUVs?
|
After decades of development, ASML shipped the first production extreme ultraviolet lithography machine in 2013. These machines produce light in the 13.5 nm wavelength range when a high-energy laser is focused on microscopic droplets of molten tin to produce a plasma, which then emits EUV light. The light is bounced off Zeiss mirrors that are the flattest mirrors in the world, on to the surface of a silicon wafer to deliver the designs for the chip. ASML's best-selling EUV product has been the Twinscan NXE:3600D, which costs up to $200 million. Shipping the machine requires 40 shipping containers, 20 trucks and three Boeing 747s. As of 2022, ASML has shipped around 140 EUV systems, and it is the only company to manufacture them.
ASML is working on the next generation of EUV systems, with the first shipments to customers for R&D purposes expected to take place at the end of 2023. The platform is designated High-NA as it will increase the numerical aperture (NA) from 0.33 to 0.55, and each system is expected to cost $300 million.
|
The best-selling EUV is the Twinscan NXE:3600D, and it takes 3 Boeing 747s per EUV, so 30 Boeing 747s are required to ship ten Twinscan NXE:3600Ds.
|
closed_qa
| 7,724 |
What is Bubble tea?
|
Bubble tea (also known as pearl milk tea, bubble milk tea, tapioca milk tea, boba tea, or boba; Chinese: 珍珠奶茶; pinyin: zhēnzhū nǎichá, 波霸奶茶; bōbà nǎichá) is a tea-based drink that originated in Taiwan in the early 1980s. Taiwanese immigrants brought it to the United States in the 1990s, initially in California through regions like Los Angeles County, but the drink has also spread to other countries where there is a large East Asian diaspora population.
Bubble tea most commonly consists of tea accompanied by chewy tapioca balls ("boba" or "pearls"), but it can be made with other toppings as well, such as grass jelly, aloe vera, red bean, or popping boba. It has many varieties and flavors, but the two most popular varieties are pearl black milk tea and pearl green milk tea ("pearl" signifies the tapioca balls at the bottom).
|
Boba tea is a very delicious drink originally from Taiwan. It started with cold milk tea with tapioca balls in the early 1990s. When the demand gets so popular, the boba tea store owner tries to be fancier by adding different toppings such as grass jelly, pudding cluster, aloe vera, red beans, gummy, mochi and fruit bites. In addition, many store owners become more creative by using different flavors of tea (black, green, oolong, jasmine and other fragrance tea) as a drink base to outstand other competitors.
|
closed_qa
| 7,725 |
When was the attack on Pearl Harbor
|
The attack on Pearl Harbor[nb 3] was a surprise military strike by the Imperial Japanese Navy Air Service upon the United States against the U.S. naval base at Pearl Harbor in Honolulu, Territory of Hawaii, just before 8:00 a.m. (local time) on Sunday, December 7, 1941. The United States was a neutral country at the time; the attack led to its formal entry into World War II the next day. The Japanese military leadership referred to the attack as the Hawaii Operation and Operation AI,[nb 4] and as Operation Z during its planning.
The attack was preceded by months of negotiations between the U.S. and Japan over the future of the Pacific. Japanese demands included that the U.S. end its sanctions against Japan, cease aiding China in the Second Sino-Japanese war, and allow Japan to access the resources of the Dutch East Indies. Anticipating a negative response from the US, Japan sent out its naval attack groups in November 1941 just prior to receiving the Hull note—the U.S. demand that Japan withdraw from China and Indochina.
Japan intended the attack as a preventive action. Its aim was to prevent the United States Pacific Fleet from interfering with its planned military actions in Southeast Asia against overseas territories of the United Kingdom, the Netherlands, and those of the United States. Over the course of seven hours there were coordinated Japanese attacks on the U.S.-held Philippines, Guam, and Wake Island and on the British Empire in Malaya, Singapore, and Hong Kong.
|
December 7, 1941
|
closed_qa
| 7,726 |
Given this paragraph about the Northamptonshire County Cricket Club, can you list down some points that can be inferred about the County Championship?
|
Northamptonshire County Cricket Club is in Division Two of the County Championship; the team (also known as The Steelbacks) play their home games at the County Cricket Ground, Northampton. They finished as runners-up in the Championship on four occasions in the period before it split into two divisions.
In 2013 the club won the Friends Life t20, beating Surrey in the final. Appearing in their third final in four years, the Steelbacks beat Durham by four wickets at Edgbaston in 2016 to lift the Natwest t20 Blast trophy for the second time. The club also won the NatWest Trophy on two occasions, and the Benson & Hedges Cup once.
|
Based on this paragraph, it seems like the Country Championship refers to some form of organized competition between cricket teams belonging to different counties. The Championship has been organized for at least four times given that the Northamptonshire County Cricket Club finished as runners-up in it for four times. It also seems like the Championship was split into two divisions at some point.
|
closed_qa
| 7,729 |
What is another name for downhill skiing?
|
Downhill skiing is also known as alpine skiing
|
open_qa
| 7,731 |
|
Who founded Linkedin?
|
Reid Hoffman is the founder of Linkedin.
|
open_qa
| 7,732 |
|
What is 12-3-30?
|
12-3-3- is the viral workout trend that's been popularized on social media. It entails walking on a treadmill at an incline of 12, a speed of 3 mph, for 30 minutes.
|
open_qa
| 7,736 |
|
How did actor James Dean die?
|
Car accident
|
open_qa
| 7,737 |
|
Which NFL franchise was ripped away from hits hometown and renamed the Baltimore Ravens?
|
Cleveland Browns
|
open_qa
| 7,738 |
|
Kartavya Path was called in the name of
|
Kingsway
|
open_qa
| 7,739 |
|
Who is the protagonist in CyberPunk 2077?
|
Cyberpunk 2077 is a 2020 action role-playing video game developed by CD Projekt Red and published by CD Projekt. Set in Night City, an open world set in the Cyberpunk universe, players assume the role of a customisable mercenary known as V, who can acquire skills in hacking and machinery with options for melee and ranged combat. The main story follows V's struggle as they deal with a mysterious cybernetic implant that threatens to overwrite their body with the personality and memories of a deceased celebrity only perceived by V; the two must work together to be separated and save V's life.
|
The main story revolves around the protagonist V, as they deal with a mysterious cybernetic implant that threatens to overwrite their body with another person's memories.
|
closed_qa
| 7,740 |
Which movie features the original song, "City of Stars"?
|
La La Land, a 2016 film featuring a jazz pianist, Seb, and an aspiring actress, Mia.
|
open_qa
| 7,742 |
|
Is success important?
|
Absolutely not. If you what you do (anything that is legal and ethical), then that's what's important. Love the process more and worry less about the result.
|
general_qa
| 7,743 |
|
If the Curated Golden Square was built as planned, what would the average cost (rounded to the nearest dollar) per square foot have been?
|
In 2019, Singh had stated his next venture, set to open October 2019, was Curated Golden Square, described as a "$100 million, 30,000 square foot apartment hotel". In a 2021 follow up interview with Vanity Fair, Singh claimed that the COVID-19 pandemic was the reason the venture did not move forward. The site in question, 37 Golden Square, is a collection of 23 apartments developed by Halamar in 2019.
|
$3,333 per square foot = $100,000,000/ 30,000 square feet
|
closed_qa
| 7,744 |
What is the Oxford Comma?
|
In English-language punctuation, a serial comma (also called a series comma, Oxford comma, or Harvard comma) is a comma placed immediately after the penultimate term (i.e., before the coordinating conjunction, such as and or or) in a series of three or more terms. For example, a list of three countries might be punctuated either as "France, Italy and Spain" (without the serial comma) or "France, Italy, and Spain" (with the serial comma).
|
open_qa
| 7,745 |
|
How to play tic-tac-toe
|
There is no universally-agreed rule as to who plays first, but in this article the convention that X plays first is used.
Players soon discover that the best play from both parties leads to a draw. Hence, tic-tac-toe is often played by young children who may not have discovered the optimal strategy.
Because of the simplicity of tic-tac-toe, it is often used as a pedagogical tool for teaching the concepts of good sportsmanship and the branch of artificial intelligence that deals with the searching of game trees. It is straightforward to write a computer program to play tic-tac-toe perfectly or to enumerate the 765 essentially different positions (the state space complexity) or the 26,830 possible games up to rotations and reflections (the game tree complexity) on this space. If played optimally by both players, the game always ends in a draw, making tic-tac-toe a futile game.
|
Tic-tac-toe is played on a three-by-three grid by two players, who alternately place the marks X and O in one of the nine spaces in the grid. Tic-tac-toe (American English), noughts and crosses (Commonwealth English), or Xs and Os (Canadian or Irish English) is a paper-and-pencil game for two players who take turns marking the spaces in a three-by-three grid with X or O. The player who succeeds in placing three of their marks in a horizontal, vertical, or diagonal row is the winner. It is a solved game, with a forced draw assuming best play from both players.
|
closed_qa
| 7,747 |
Name five different cheeses.
|
Five different cheeses are mozzarella, parmesan, gouda, cheddar, and gruyere.
|
open_qa
| 7,748 |
|
What is the origin of the Easter Egg in video games?
|
An Easter egg is a message, image, or feature hidden in software, a video game, a film, or another — usually electronic — medium. The term used in this manner was coined around 1979 by Steve Wright, the then-Director of Software Development in the Atari Consumer Division, to describe a hidden message in the Atari video game Adventure, in reference to an Easter egg hunt. The earliest known video game Easter egg is in Moonlander (1973), in which the player tries to land a Lunar module on the moon; if the player opts to fly the module horizontally through several of the game's screens, they encounter a McDonald's restaurant, and if they land next to it the astronaut will visit it instead of standing next to the ship. The earliest known Easter egg in software in general is one placed in the "make" command for PDP-6/PDP-10 computers sometime in October 1967–October 1968, wherein if the user attempts to create a file named "love" by typing "make love", the program responds "not war?" before proceeding.
|
The term used in this manner was coined around 1979 by Steve Wright, the then-Director of Software Development in the Atari Consumer Division, to describe a hidden message in the Atari video game Adventure
|
closed_qa
| 7,752 |
Can you give me a short summary of Mindfulness and how to practice it?
|
Mindfulness is a technique that can be used to bring your mind and focus into the present moment, and calm your nervous system.
The most common way to begin to practice mindfulness is to narrow and focus your attention on your breath. Some techniques prefer breathing in through the nose and out through the mouth, although this is not required. One way to narrow your attention is to closely observe the sensation of cool air as it passes over the tip of your nose, and the sensation of your chest falling as you exhale. Allow any rising thoughts to pass through your mind without paying attention to them, or engaging with them.
Other techniques involve focusing your attention to sensations in your body like hot and cold, or pain. You can also bring your focus to feelings like fear, anxiety, or love - focus your attention on where exactly in the body you feel those feelings. You can also move your attention to external stimulus like sounds, and your visual field.
Mindfulness is an extremely powerful technique that anyone can do from anywhere. Good luck practicing!
|
general_qa
| 7,753 |
|
Why is the traffic so bad in Seattle Tuesday through Thursday?
|
One possible explanations is that they are common commute days in a week. The traffic is bad in Seattle attributes to several factors: it's a major metropolitan city with almost 2 million people in the area; its geographic features that prevent building roads more extensively esp connecting segments/patches across lakes and rivers; big companies such as Boeing, Microsoft, Amazon have big footprints in Seattle and the locations of their offices spread the area can also force people to commute around in workdays.
|
general_qa
| 7,759 |
|
Which soccer player has the most number of career goals?
|
Cristiano Ronaldo has the highest number of career goals. His current tally is 834 goals. He is still active as a professional soccer player. Lionel Messi is currently in third place with 803 goals and is also active.
|
open_qa
| 7,760 |
|
How do I create knit stitches?
|
In patterns a knit stitch is often abbreviated as k. A knit stitch is the first basic stitch to learn. Hold the needle with the cast-on stitches in your left hand and the second empty needle in your right hand. The yarn that is coming from your skein or ball of yarn should be held toward the back of your work and this yard strand is considered your working yard. Push the empty needle into the first loop between the first and second stitch from left to right. Grab the working yarn with your right hand and loop it right to left behind the needle that you just pushed into the first stitch. Keeping that loop on the right needle, slide the needle tips toward each other so the stitch on the left needle can fall off of the needle , keeping the loop on the right needle that you created. This is your first knit stitch. Continue the pattern to the end of the row.
|
general_qa
| 7,762 |
|
What season does Easter happen during?
|
Easter is a Spring holiday
|
open_qa
| 7,763 |
|
Given a reference text about the Parliamentary Commissioner for Standards, how is the position appointed?
|
The Parliamentary Commissioner for Standards is an officer of the British House of Commons. The work of the officer is overseen by the Commons Select Committee on Standards.
The current commissioner is Daniel Greenberg.
Duties
The commissioner is in charge of regulating MPs' conduct and propriety. One of the commissioner's main tasks is overseeing the Register of Members' Financial Interests, which is intended to ensure disclosure of financial interests that may be of relevance to MPs' work.
The Commissioner is the decision-maker in cases from the Independent Complaints and Grievance Scheme where the respondent is a Member of Parliament. If the Commissioner deems a sanction warranted, they refer cases to the Independent Expert Panel so the appropriate sanction can be determined.
The Parliamentary Commissioner for Standards is appointed by a resolution of the House of Commons for a fixed term of five years and is an independent officer of the House, working a four-day week. The remit of the Parliamentary Commissioner for Standards does not extend to the House of Lords: the post of Lords Commissioner for Standards was created in 2010.
|
The Parliamentary Commissioner for Standards is appointed by a resolution of the House of Commons for a fixed term of five years.
|
closed_qa
| 7,765 |
Why is the sky blue?
|
The earth's sky is blue due to how the gases in the earth's atmosphere scatter the short electromagnetic wavelengths of the sun's blue light while allowing red, orange and yellow light to pass through. The scientific name for this phenomenon is Rayleigh scattering.
|
general_qa
| 7,767 |
|
What are some key considerations when deciding whether or not to implement ERP in my organization?
|
There are many considerations to take into account when deciding if you will implement an ERP in your organization. Common considerations include implementation cost, run costs, and implementation time. There are also a host of other very important, but less obvious, considerations that should be examined carefully, including: organizational change, the organization's capacity to train its employees, and IT/InfoSec strategy.
|
general_qa
| 7,769 |
|
What's the difference between Spiders and insects?
|
Even though both spiders and insects are exoskeletons, Spiders are not insects. Spiders have eight legs, and all insects have six legs.
|
general_qa
| 7,770 |
|
What is the difference between leadership and management?
|
Leadership means influencing people toward a right direction. Management means organizing people to achieve a goal. In other words, leadership does right things, management does things right.
In a business or a society, different people often have different opinions. A good leadership can influence a large number of people toward a direction that will generate positive impact on the business or the society. Leadership can be seen in most aspects of human society, from choosing a vacation destination to becoming a president.
Most business or social activities require multiple people to accomplish. A good management can organize a large number of people to accomplish complex efforts with great efficacy. Good management skills can be applied to different occasions in life, from organizing a party to running a company.
|
general_qa
| 7,775 |
|
Wthat is the difference between Speed and Velocity ?
|
Speed denotes only how fast an object is moving, whereas velocity describes both how fast and in which direction the object is moving. If a car is said to travel at 60 miles per hour, its speed has been specified. However, if the car is said to move at 60 miles per hour to the north, its velocity has now been specified.
The big difference can be discerned when considering movement around a circle. When something moves in a circular path and returns to its starting point, its average velocity is zero, but its average speed is found by dividing the circumference of the circle by the time taken to move around the circle. This is because the average velocity is calculated by considering only the displacement between the starting and end points, whereas the average speed considers only the total distance travelled.
|
open_qa
| 7,776 |
|
Given this paragraph about kubernetes, what is the storage layer of Kubernetes control plane?
|
The Kubernetes master node handles the Kubernetes control plane of the cluster, managing its workload and directing communication across the system. The Kubernetes control plane consists of various components, each its own process, that can run both on a single master node or on multiple masters supporting high-availability clusters. The various components of the Kubernetes control plane are as follows:
etcd is a persistent, lightweight, distributed, key-value data store that CoreOS has developed. It reliably stores the configuration data of the cluster, representing the overall state of the cluster at any given point of time. etcd favors consistency over availability in the event of a network partition (see CAP theorem). The consistency is crucial for correctly scheduling and operating services.
The API server serves the Kubernetes API using JSON over HTTP, which provides both the internal and external interface to Kubernetes. The API server processes and validates REST requests and updates the state of the API objects in etcd, thereby allowing clients to configure workloads and containers across worker nodes. The API server uses etcd's watch API to monitor the cluster, roll out critical configuration changes, or restore any divergences of the state of the cluster back to what the deployer declared. As an example, the deployer may specify that three instances of a particular "pod" (see below) need to be running. etcd stores this fact. If the Deployment Controller finds that only two instances are running (conflicting with the etcd declaration), it schedules the creation of an additional instance of that pod.
The scheduler is the extensible component that selects on which node an unscheduled pod (the basic entity managed by the scheduler) runs, based on resource availability. The scheduler tracks resource use on each node to ensure that workload is not scheduled in excess of available resources. For this purpose, the scheduler must know the resource requirements, resource availability, and other user-provided constraints or policy directives such as quality-of-service, affinity vs. anti-affinity requirements, and data locality. The scheduler's role is to match resource "supply" to workload "demand".
A controller is a reconciliation loop that drives the actual cluster state toward the desired state, communicating with the API server to create, update, and delete the resources it manages (e.g., pods or service endpoints). One kind of controller is a Replication Controller, which handles replication and scaling by running a specified number of copies of a pod across the cluster. It also handles creating replacement pods if the underlying node fails. Other controllers that are part of the core Kubernetes system include a DaemonSet Controller for running exactly one pod on every machine (or some subset of machines), and a Job Controller for running pods that run to completion (e.g., as part of a batch job). Labels selectors that are part of the controller's definition specify the set of pods that a controller manages.
The controller manager is a process that manages a set of core Kubernetes controllers.
|
ETCD
|
closed_qa
| 7,777 |
What is the difference between instant oatmeal and regular oatmeal?
|
Instant oatmeal is ready to eat immediately after sitting in hot water, whereas regular oatmeal has to be boiled in hot water for a longer period of time (the specific duration depends on the type of oats).
|
open_qa
| 7,782 |
|
Which states produced more than 10% of total US oil production in 2020?
|
The leading oil-producing area in the United States in 2019 was Texas (5.07 million barrels (806,000 m3) per day), followed by the offshore federal zone of the Gulf of Mexico (1.90 million barrels (302,000 m3) per day), North Dakota (1.42 million barrels (226,000 m3) per day) and New Mexico (0.90 million barrels (143,000 m3) per day). In 2020, the top five U.S. oil producing states were Texas (43%), North Dakota (10.4%), New Mexico (9.2%), Oklahoma (4.1%), and Colorado (4.0%).
|
Texas and North Dakota produced 43% and 10.4% of US oil in 2020, respectively.
|
closed_qa
| 7,787 |
How much wood could a woodchuck chuck if a woodchuck could chuck wood?
|
The answer to this depends on various factors. If the wood if very heavy, a woodchuck may not be capable of chucking it at all. If the pieces are smaller and the woodchuck was relatively young and spritely, then they could probably chuck at least 30 to 40lbs within a few hours. An older woodchuck may no longer have dexterity in its hands or the sufficient strength needed to chuck any piece of wood regardless of its size or weight.
|
general_qa
| 7,788 |
|
What is the emblem of the United States Marine Corps?
|
Approved and adopted in 1868, the Eagle, Global and Anchor is the official emblem and insignia of the United States Marine Corps.
|
open_qa
| 7,790 |
|
What is the difference between mozzarella and cheddar?
|
Mozzarella (or Mozz) can be served fresh, while cheddar is generally aged for some time to improve flavor before it is consumed.
|
open_qa
| 7,791 |
|
What are the benefits of meditation?
|
Meditation enhances focus, memory, and mood. Meditation has also been shown to have other benefits such as reducing the negative impacts of lack of sleep.
|
general_qa
| 7,798 |
|
Given a reference text about Adventfjorden, how wide and long is it?
|
Adventfjorden (Advent Bay) is a 7 km long and 4 km wide bay running south-eastwards from the southern side of Isfjorden, on the west coast of Spitsbergen in Svalbard. The name represents a corruption of Adventure Bay - probably named after the Hull-built whaleship Adventure, which operated in Isfjorden in 1656. The fjord was originally[when?] known as Klass Billen Bay. At the head of Adventfjorden is Adventdalen (Advent Valley).
The former mining-camp of Longyearbyen (now Svalbard's main town) lies on the fjord's southwestern shore, while another former mining-camp, Hiorthhamn, is located on its northeastern shore.
|
Adventfjorden is 4km wide and 7km long.
|
closed_qa
| 7,799 |
Where does the name of the UK county 'Essex' originate from?
|
The name Essex originates in the Anglo-Saxon period of the Early Middle Ages and has its root in the Anglo-Saxon (Old English) name Ēastseaxe ("East Saxons"), the eastern kingdom of the Saxons who had come from the continent and settled in Britain. Excavations at Mucking have demonstrated the presence of Anglo-Saxon settlers in the early fifth century, however the way in which these settlers became ascendent in the territory of the Trinovantes is not known. Studies suggest a pattern of typically peaceful co-existence, with the structure of the Romano-British landscape being maintained, and with the Saxon settlers believed to have been in the minority.
|
The name Essex originates in the Anglo-Saxon period of the Early Middle Ages and has its root in the Anglo-Saxon (Old English) name Ēastseaxe ("East Saxons").
|
closed_qa
| 7,801 |
What do the suits on a deck of cards represent?
|
Each of the suits on a deck of cards represents the four major pillars of the economy in the middle ages: heart represented the Church, spades represented the military, clubs represented agriculture, and diamonds represented the merchant class.
|
open_qa
| 7,805 |
|
What is the most popular opening in chess?
|
The most popular opening in chess changes dramatically based on the skill level of the players. At a professional level, some of the most popular openings include the Sicilian Defence, the Ruy Lopez, or Spanish Opening, and the Italian Game. At a beginner level, popular openings include the London Opening, Sicilian Dragon, and King's Indian Defence.
|
open_qa
| 7,806 |
|
What language should I learn?
|
If you are interested in verbal languages, the most popular languages are English, Mandarin, Hindi, and Spanish. Learning one of these languages will allow you to communicate with over half a billion people! However, it also depends on your interests, such as travel interests or friends, who might speak these languages. If you are interested in non-verbal languages, American Sign Language (ASL) is the most popular non-verbal language.
|
general_qa
| 7,807 |
|
Which era of counterculture were the Beatles pivotal to?
|
he Beatles were an English rock band, formed in Liverpool in 1960, that comprised John Lennon, Paul McCartney, George Harrison and Ringo Starr. They are regarded as the most influential band of all time and were integral to the development of 1960s counterculture and popular music's recognition as an art form. Rooted in skiffle, beat and 1950s rock 'n' roll, their sound incorporated elements of classical music and traditional pop in innovative ways; the band also explored music styles ranging from folk and Indian music to psychedelia and hard rock. As pioneers in recording, songwriting and artistic presentation, the Beatles revolutionised many aspects of the music industry and were often publicised as leaders of the era's youth and sociocultural movements
|
The Beatles were integral to the development of 1960s counterculture
|
closed_qa
| 7,809 |
Based on the reference text about Bruce Nodwell, what did he create?
|
Bruce Nodwell, OC (May 12, 1914 – January 20, 2006) was a Canadian inventor who invented the Nodwell 110, a multi-purpose two-tracked vehicle capable of traversing a wide variety of adverse terrain, including sand, mud, muskeg, swamp, and snow.
In 1970, he was made an Officer of the Order of Canada, Canada's highest civilian honor, "for his contribution to the opening of the Canadian North through his inventions and development of various types of tracked vehicles". A mountain in Antarctica "Nodwell Peaks" and a lake in NWT bear his name.
|
Bruce Nodwell invented the Nodwell 110, a two-tracked vehicle capable of traversing a wide variety of terrain.
|
closed_qa
| 7,810 |
What made Jackson decide to pursue acting?
|
In Seattle, Jackson worked as an ad executive at a magazine and did some theater work on the side, earning his Equity card. "As soon as I found out what theater was, what Broadway was, I thought, 'Oh, that's what I'll do with my life.' Just a matter of getting all the pieces in place", he said. Inspired to rethink his career after the September 11 attacks, he moved to New York City to pursue his dream of being an actor: "[Acting] was something I always wanted to do but I was too scared and didn't have the confidence. 9/11 changed everything for all of us. It gave me the urgency."
|
The occurrence of the September 11 attacks
|
closed_qa
| 7,813 |
Given a reference text about the Mid-South Grizzlies vs NFL, what was the result of the lawsuit?
|
Mid-South Grizzlies v. NFL, 720 F.2d 772 (3d Cir. 1983), was a lawsuit filed by John F. Bassett, the owner of the World Football League's Memphis Grizzlies against the National Football League claiming that the NFL violated the antitrust laws by refusing to admit his club to their league.
The court found that the NFL had not acquired or maintained its monopoly power unlawfully and that the refusal to expand to Memphis did not contribute to its maintenance. It further elaborated that such refusal was actually procompetitive because it left the Memphis area open to rival leagues. By the time the lawsuit had settled, Bassett had gone on to found the Tampa Bay Bandits of the United States Football League, while Memphis received the Memphis Showboats of the same league. As such, the case effectively became moot. (Incidentally, the USFL would go on to file a much more famous antitrust suit against the NFL a few years later, which while successfully decided against the NFL, provided only a cursory monetary award to the USFL; ironically, Bassett was an outspoken opponent of that lawsuit.)
|
The court ruled that the NFL had not acquired or maintained its monopoly power unlawfully and that the refusal to expand to Memphis did not contribute to its maintenance.
|
closed_qa
| 7,814 |
What is cuban cuisine?
|
Cuban cuisine refers to the food eaten in the country of Cuba. Popular dishes usually include a protein/meat, rice and some type of veggie. Cuban food tends to have a combination of the following spices; salt, pepper, cumin, onion, garlic and oregano. Some of the most popular traditional dishes include picadillo, ropa vieja, media noche and empanadas. Many dishes also tend to include black beans.
|
general_qa
| 7,816 |
|
What is an atmospheric river?
|
Atmospheric rivers are relatively long, narrow regions in the atmosphere – like rivers in the sky – that transport most of the water vapor outside of the tropics. These columns of vapor move with the weather, carrying an amount of water vapor roughly equivalent to the average flow of water at the mouth of the Mississippi River. When the atmospheric rivers make landfall, they often release this water vapor in the form of rain or snow.
|
general_qa
| 7,820 |
|
Given this paragraph about Novak Djokovic, how many majors titles does he currently hold?
|
Novak Djokovic (Serbian Cyrillic: Новак Ђоковић, romanized: Novak Đoković, pronounced [nôʋaːk dʑôːkoʋitɕ] (listen); born 22 May 1987) is a Serbian professional tennis player. He is currently ranked the world No. 1 player in men's singles by the Association of Tennis Professionals (ATP), and has held the top position for a record total 381 weeks, finishing as the year-end No. 1 an Open Era record seven times. He has won a total of 93 singles titles on the men's ATP Tour with titles comprising a joint-record 22 majors, a record ten Australian Opens, a record 38 Masters, a joint-record six Tour Finals, and a record 66 Big Titles. Djokovic has completed a non-calendar year Grand Slam in singles, becoming the only man in tennis history to be the reigning champion of the four majors at once across three different surfaces. He is also the first man in the Open Era to achieve a double Career Grand Slam in singles and the only player to complete the career Golden Masters in singles by winning all of the nine Masters tournaments, which he has done twice.
|
22
|
closed_qa
| 7,825 |
If 2 carpenters can build 4 chairs in 3 hours, then how many chairs can 6 carpenters build in 6 hours?
|
If 2 carpenters can build 4 chairs in 3 hours, then a carpenter can build 1 chair in 1.5 hours. 1 carpenter can build 4 chairs in 6 hours, and 6 carpenters can build 24 chairs in 6 hours.
|
general_qa
| 7,827 |
|
What is the difference between UK and Great Britain?
|
Quite often people uses the two interchangeable, however this is not correct. Great Britain is the official name of of England, Scotland and Wales. It does not include Northern Ireland. the UK on the other hand is the official name of the union between England, Scotland, Wales and Northern Ireland.
|
general_qa
| 7,830 |
|
How do I turn on my Tesla Model Y?
|
When you open a door, Tesla Model Y powers on the touchscreen and you can operate all controls. To drive Model Y:
1. PRESS THE BRAKE PEDAL – Model Y powers on and is ready to drive.
2. SELECT A GEAR – Move the drive stalk all the way down for Drive and all the way up for Reverse.
NOTE: If the PIN to Drive feature is enabled, you must also enter a valid PIN on the touchscreen before you can drive Model Y. Everything you need to know when driving Model Y displays on the touchscreen.
Drive Disabled – Requires Authentication
If Model Y does not detect a key when you press the brake (an authenticated phone is not detected, or 30 seconds has passed since you used the key card), the touchscreen displays a message telling you that driving requires authentication. If you see this message, place the key card behind the cup holders on the top of the center console where the RFID transmitter can read it. The 30 second authentication window restarts and you can start Model Y by pressing the brake pedal.
A number of factors can affect whether Model Y can detect an authenticated phone (for example, the phone’s battery is low or dead and is no longer able to communicate using Bluetooth). Always keep your authenticated phone and a key card with you. After driving, your authenticated phone or key card is needed to restart Model Y after it powers off. And when you leave Model Y, you must bring your authenticated phone or key card with you to lock Model Y, either manually or automatically.
|
general_qa
| 7,831 |
|
What states do not have a state gambling lottery?
|
Alabama, Alaska, Hawaii, Nevada, and Utah.
|
open_qa
| 7,832 |
|
Given these paragraphs about Multiomics, what is panomics?
|
Multiomics, multi-omics, integrative omics, "panomics" or "pan-omics" is a biological analysis approach in which the data sets are multiple "omes", such as the genome, proteome, transcriptome, epigenome, metabolome, and microbiome (i.e., a meta-genome and/or meta-transcriptome, depending upon how it is sequenced); in other words, the use of multiple omics technologies to study life in a concerted way. By combining these "omes", scientists can analyze complex biological big data to find novel associations between biological entities, pinpoint relevant biomarkers and build elaborate markers of disease and physiology. In doing so, multiomics integrates diverse omics data to find a coherently matching geno-pheno-envirotype relationship or association. The OmicTools service lists more than 99 softwares related to multiomic data analysis, as well as more than 99 databases on the topic.
Systems biology approaches are often based upon the use of panomic analysis data. The American Society of Clinical Oncology (ASCO) defines panomics as referring to "the interaction of all biological functions within a cell and with other body functions, combining data collected by targeted tests ... and global assays (such as genome sequencing) with other patient-specific information."
Single-cell multiomics
A branch of the field of multiomics is the analysis of multilevel single-cell data, called single-cell multiomics. This approach gives us an unprecedent resolution to look at multilevel transitions in health and disease at the single cell level. An advantage in relation to bulk analysis is to mitigate confounding factors derived from cell to cell variation, allowing the uncovering of heterogeneous tissue architectures.
Methods for parallel single-cell genomic and transcriptomic analysis can be based on simultaneous amplification or physical separation of RNA and genomic DNA. They allow insights that cannot be gathered solely from transcriptomic analysis, as RNA data do not contain non-coding genomic regions and information regarding copy-number variation, for example. An extension of this methodology is the integration of single-cell transcriptomes to single-cell methylomes, combining single-cell bisulfite sequencing to single cell RNA-Seq. Other techniques to query the epigenome, as single-cell ATAC-Seq and single-cell Hi-C also exist.
A different, but related, challenge is the integration of proteomic and transcriptomic data. One approach to perform such measurement is to physically separate single-cell lysates in two, processing half for RNA, and half for proteins. The protein content of lysates can be measured by proximity extension assays (PEA), for example, which use DNA-barcoded antibodies. A different approach uses a combination of heavy-metal RNA probes and protein antibodies to adapt mass cytometry for multiomic analysis.
Multiomics and machine learning
In parallel to the advances in highthroughput biology, machine learning applications to biomedical data analysis are flourishing. The integration of multi-omics data analysis and machine learning has led to the discovery of new biomarkers. For example, one of the methods of the mixOmics project implements a method based on sparse Partial Least Squares regression for selection of features (putative biomarkers).
https://en.wikipedia.org/wiki/Multiomics
|
The American Society of Clinical Oncology (ASCO) defines panomics as referring to "the interaction of all biological functions within a cell and with other body functions, combining data collected by targeted tests ... and global assays (such as genome sequencing) with other patient-specific information."
|
closed_qa
| 7,834 |
What advice would you give to FBLA competitors for future years?
|
Please do not procrastinate and really focus on the prejudged part of the portion of your report, because that is a prerequisite if you want to compete at states. Also, make sure to thoroughly read the rubric so you hit every single requirement on the rubric, especially the part about providing a recommendation and plan. As for your recommendation, try to come up with a creative acronym to make it memorable. For us, we thought of CHIP, as the topic was about microchips. Although notes are technically allowed, every single team memorizes their presentation, so make sure to have your presentation very well memorized by the conference. Also it is important to get plenty of sleep before the night of the competition, eat breakfast, and act confident when you are presenting. Finally, if you do make a mistake it is okay (part of the learning), just don't act surprised and keep going!
|
general_qa
| 7,835 |
|
In the Impeachment proceeding against Donald Trump, the motion was passed by?
|
229 votes against 197 in the House of Representatives
|
open_qa
| 7,837 |
|
What caused Africa's integration into the Roman System?
|
Following the conquest of North Africa's Mediterranean coastline by the Roman Empire, the area was integrated economically and culturally into the Roman system. Roman settlement occurred in modern Tunisia and elsewhere along the coast. The first Roman emperor native to North Africa was Septimius Severus, born in Leptis Magna in present-day Libya—his mother was Italian Roman and his father was Punic.
|
Rome's conquest of North Africa's Mediterranean coastline lead to Africa's integration into the Roman System.
|
closed_qa
| 7,839 |
Why are people migrating in the US from the NE and Mid-West to the South and SE?
|
better weather year round
|
general_qa
| 7,840 |
|
Who were the "Big Four" of Grunge?
|
Alice in Chains, Soundgarden, Nirvana, and Pearl Jam.
|
open_qa
| 7,841 |
|
What was the hit single on Nek's 1996 Album Lei, gli amici e tutto il resto?
|
Lei, gli amici e tutto il resto (She, friends and everything else), is the fourth studio album by Italian singer-songwriter Nek. It was released in 1996, as his first studio album with Warner Music Group. It was re-released on 1 March 1997, after the success of the single "Laura non c'è", which had not been included in the album.
Since 1999 there have been reported sales of over 2 million copies all over the world.
|
Laura non c'è" was the hit single, but wasn't added until the album was released in 1997.
|
closed_qa
| 7,842 |
Where can you find Lygodactylus gutturalis?
|
Lygodactylus gutturalis, also known as the Uganda dwarf gecko or chevron-throated dwarf gecko, is a species of gecko. It is widely distributed in Sub-Saharan Africa from near the Equator northward. Subspecies Lygodactylus gutturalis dysmicus is endemic to Cameroon, and subspecies Lygodactylus gutturalis paurospilus to Tanzania.
|
Lygodactylus gutturalis is a species of gecko commonly found in Sub-Saharan Africa from near the Equator northward.
|
closed_qa
| 7,845 |
Tell me why your dog likes dog daycare.
|
My dog has a lot of energy and is an extrovert with both people and other dogs. He gets so excited in the car on the way there! I like the fact that the dogs' play is supervised by trained dog specialists, and that dogs who are getting too aggressive are placed in a timeout in a crate to settle down. I like that it's indoors so it can continue in the winter months and rain or shine. I like that they have a nap in the middle of the day so they can re-charge for the afternoon play session. While my dog doesn't got there for more than 9 hours, it is convenient that the daycare is open from 7am to 7pm in case I needed him to stay there longer. I like that they have two separate playrooms at our daycare, one for smaller breeds/older dogs/timid dogs, and the other for larger dogs/younger dogs who may want to roughhouse more. Another great benefit is that my daycare offers spa services for my dog like a bath, nail trimming, ear cleaning, teeth brushing, and I do take advantage of that every other month or so. Last, if we are going out of town, and my son can't come over to watch our dog, the dog daycare center does offer boarding services. I would highly recommend that you check it out!
|
general_qa
| 7,846 |
|
What is the art of command
|
It is the art of influencing human behavior in order to achieve the objective assigned by the superior.
|
open_qa
| 7,848 |
|
How many professional basketball teams are based in California?
|
California has 4 basketball teams: the Golden State Warriors, the Los Angeles Clippers, the Los Angeles Lakers, and the Sacramento Kings.
|
open_qa
| 7,852 |
|
Prove that 2 + 2 = 5.
|
2 + 2 does not equal 5, it equals 4.
|
general_qa
| 7,855 |
|
Which team's have the most NCAA Division I men's basketball championships?
|
1. UCLA has 11 championship wins
2. Kentucky has 8 championship wins
3. North Carolina has 6 championship wins
4. Due has 5 championship wins
5. Indian has 5 championship wins
|
open_qa
| 7,857 |
|
What are some of the pros and cons of owning a pet?
|
There are many pros and cons of pet ownership. On the positive side interacting with your pet can provide a great way of relaxing and reducing stress in your life. If your pet is a dog it can be a great way to encourage you to get exercise. If you have a young child it can be a way of teaching them responsibility. On the down side, owning a per means you are obligated to feed, clean up after and otherwise take care of them - responsibilities you will have no matter what else going on in your life.
|
general_qa
| 7,858 |
|
What type of battery should I get to power my trolling motor?
|
Traditionally the answer is to utilize a deep cycle marine lead acid battery. These batteries are similar to a car battery but instead of having a high amount of cold cranking amps they have the ability to be run to a lower state of charge without damage. A better solution is to use a LiFePO4 battery. These batteries may have a higher initial cost, but will generally last longer than the traditional battery while providing more usable capacity and having a substantially lower weight.
|
general_qa
| 7,860 |
|
How long did the Roman Empire last
|
In modern historiography, Ancient Rome refers to Roman civilisation from the founding of the Italian city of Rome in the 8th century BC to the collapse of the Western Roman Empire in the 5th century AD. It encompasses the Roman Kingdom (753–509 BC), Roman Republic (509–27 BC) and Roman Empire (27 BC–476 AD) until the fall of the western empire.
|
1229 years
|
closed_qa
| 7,861 |
What are some nice activities to do in the Netherlands in spring?
|
There are many interesting and enjoyable activities that you can do in the Netherlands in spring. For instance, you can go to Keukenhof, a unique park filled with fantastic displays of tulips of all colors, shapes and sizes. Walking through the scenic parks of Amsterdam, such as Vondelpark or Oosterpark, is also pleasant. I also suggest visiting the beach: Zandvoort or Scheveningen are two of the most popular beach towns in the country.
|
general_qa
| 7,862 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.