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Arthroskopie.90120079.eng.abstr
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Arthroskopie.90120079.eng.abstr
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"This study was carried out from 1986 to 1996 to evaluate the technique of translaminal epidural endoscopic discectomy in lumbar hernias occupying over 50% of the radicular canal , foraminal hernias , and hernias invading it entirely . This minimally invasive arthroscopic technique was applied in patients suffering from degenerative lumbar stenosis between L3 and S1. The first part of the study dealt with lumbar hernias . Of a total of 222 patients , 175 ( 78.82% ) showed radicular canal invasion ranging between 50 and 90% . The disc level was L4-L5 in 59% , L5-S1 in 39% , and L3-L4 in 4% . Most of these hernias were lateral extrusions . However , the study also included protrusions and foraminal hernias , since they were large and technically difficult to operate on . In terms of distribution , 25 patients ( 14.28% ) had protrusions and 120 ( 68.57% ) extrusions , and in 30 patients ( 17.14% ) hernias had migrated . Surgery was carried out by the biportal posterior approach through the flaval ligament . An irrigation pump was used and the structures were under permanent accurate arthroscopic visualization . Good results were obtained in 96% , fair in 3% , and poor in 1% . The second part of the study dealt with lateral stenosis . Drawing from the experience gained by experiments performed in 1993 on five cadavers and by translaminar epidural endoscopy since 1986 , this surgical technique was designed to provide decompression by resection of the ventral zone of the articular facet and , in some cases , foramenostomy . Of the 19 patients treated , nine presented with pathology in one segment , nine in two segments , and one in three segments . All had lumbar and sciatic complaints , intermittent neurological claudication and predominantly lateral sensory motor deficit . The general results were good in 84% and fair in 16% ."
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Arthroskopie.90120085.eng.abstr
|
Arthroskopie.90120085.eng.abstr
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[
{
"id": "Arthroskopie.90120085.eng.abstr-passage-0",
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"text": [
"Endoscopic techniques in the spine have become possible with improvements in instrumentation . Other minimally invasive techniques are limited to intradiscal surgery , not at the site of the pathology . With the transforaminal approach , treatment in the epidural space has become possible . In a pilot study we investigated the pitfalls , risks , and complications of transforaminal surgery . Patient satisfaction and acceptance of the method were documented . Some 27 patients with disk pathologies at the level of the disk space , excluding extremely medially situated herniations , were treated . We used a standard posterolateral approach under local anesthesia combined with spinal morphine anesthesia . The treated levels were L5/S1 ( 11 ) , L4/5 ( 12 ) , L3/4 ( 3 ) , and L2/3 ( 1 ) . All areas could be reached by this approach . One procedure had to be abandoned because of instrumentation problems . One patient had recurrent disk herniation and had an open procedure . Two patients were reoperated because of persistent pain . No signs of reherniation could be found in these cases , but there was swelling of the nerve root and minimal scarring . One patient developed spondylodiscitis . Minor complications were trancient root paresthesia and headache postoperatively . Postoperative MRI or CT scans revealed only little scar tissue . This impression was supported in the open revisions we performed . Clinical acceptance of the procedure was excellent and the patients recovered very quickly . Endoscopic transforaminal surgery has a considerable learning curve , even when surgeons are acquainted with the posterolateral approach and arthroskopic surgery . However , it offers a good alternative to other minimally invasive procedures and has to be seen as a good alternative to open disk surgery , too ."
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] |
[] |
[] |
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] |
Arthroskopie.90120088.eng.abstr
|
Arthroskopie.90120088.eng.abstr
|
[
{
"id": "Arthroskopie.90120088.eng.abstr-passage-0",
"type": "abstract",
"text": [
"For certain indications , anterior fusion of the lumbar spine is a standard operation . The surgeon specializing in operations on the vertebral column must leam to utilize the advantages of laparoscopic surgery . However , an absolute must before applying the technique to humans is adequate training in its use in living animals . For this purpose , the pig is a highly suitable model . The surgical team comprises a surgeon experienced in spinal procedures , an abdominal surgeon with expertise in laparoscopic surgery and an experienced cameraman . In the animal model , a change in position - organ preparation from the cranial direction , a suprasymphysial approach to the vertebrae - has proved expedient ."
],
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[
0,
712
]
]
}
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{
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],
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}
]
}
] |
[] |
[] |
[
{
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{
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},
{
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{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
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},
{
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},
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{
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{
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},
{
"id": "Arthroskopie.90120088.eng.abstr-s5-r6-t1.1-t4.1",
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},
{
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},
{
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},
{
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{
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}
] |
Arthroskopie.90120092.eng.abstr
|
Arthroskopie.90120092.eng.abstr
|
[
{
"id": "Arthroskopie.90120092.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The goal of surgery using a thoracoscopic approach for the anterior reconstruction of fractures of the thoracic and lumbar spine is the reduction of postoperative pain and morbidity . Fusion of the injured segment was performed by partial corporectomy and the vertebral body reconstructed using a tricortical autogenous bone graft . A plate and screw assembly was inserted to stabilize the surgical correction . This technique was used between May 1996 on May 1998 in 100 patients with 103 fractures of the thoracic and lumbar spine . Fractures from T4 to L3 were stabilized ; most fractures occurred at the thoracolumbar junction . A monosegmental short fusion was given preference in 51 patients . A dorsoventral approach was necessary in 68 patients on account of the fracture type . Comparing a group of 30 patients who had undergone an open procedure and a similar group treated under thoracoscopic assistance , we found a marked reduction of the postoperative need for analgesics and the duration of postoperative ventilation ."
],
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[
0,
1033
]
]
}
] |
[
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]
},
{
"id": "Arthroskopie.90120092.eng.abstr-s1-t3",
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[
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},
{
"id": "Arthroskopie.90120092.eng.abstr-s1-t4",
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"text": [
"fractures"
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Arthroskopie.90120098.eng.abstr
|
Arthroskopie.90120098.eng.abstr
|
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[] |
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Arthroskopie.90120117.eng.abstr
|
Arthroskopie.90120117.eng.abstr
|
[
{
"id": "Arthroskopie.90120117.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Arthrofibrosis is a severe complication of trauma and surgery around joints with loss of motion due to an excessive fibrotic response in the repair process . Both the cause and mechanism of arthrofibrosis remain unclear . We investigated fibrotic tissue samples taken from 18 patients ( average age : 32.5 years ; range : 18-64 years ) , who underwent arthrolysis of the knee joint because of symptomatic arthrofibrosis following ligament injuries , fractures , or corrective soft tissue surgery . The mean interval between trauma and arthrolysis was 16 months . All samples were stained with HE . Monoclonal antibodies ( Ki-67, anti-PCNA , anti-factor VIII ) were applied for immunohistological localization of proliferating cells and of small vessels . Synovial tissue samples from knee joints without any detectable pathology served as controls . Arthrofibrotic tissue from the anterior joint compartment revealed synovial hyperplasia and a chronic inflammatory reaction with lymphocytes and plasma cells as well as a perivascular fibrotic enlargement . Immunostaining showed hypervascularity and an increase in proliferating cells . The stratum fibrosum of the joint capsule was enlarged by hypocellular fibrosis . Samples taken from the posterior capsule showed less cellularity and vascularity than samples from the anterior compartment . The histological findings indicate that arthrofibrosis is a fibroproliferative disorder . The chronic inflammatory process may play a crucial role in the mechanism of arthrofibrosis . A strong immune response may lead to attraction and activation of inflammatory cells and may stimulate resident cells in the synovial tissue to proliferate . Thus , arthrofibrosis may be similar to other systemic or local fibrotic disorders . However , the stimuli which triggers the fibrotic response remains unknown . Further studies are necessary to define the cause and mechanism of arthrofibrosis in order to make progress in preventing and treating this disorder ."
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},
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"id": "Arthroskopie.90120117.eng.abstr-s14-r5-t4.1-t1.1",
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},
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},
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},
{
"id": "Arthroskopie.90120117.eng.abstr-s14-r8-t1.1-t3.1",
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},
{
"id": "Arthroskopie.90120117.eng.abstr-s14-r9-t2.1-t3.1",
"type": "part_of",
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},
{
"id": "Arthroskopie.90120117.eng.abstr-s14-r10-t4.1-t2.1",
"type": "adjacent_to",
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"arg2_id": "Arthroskopie.90120117.eng.abstr-s17-t2",
"normalized": []
}
] |
Arthroskopie.90120125.eng.abstr
|
Arthroskopie.90120125.eng.abstr
|
[
{
"id": "Arthroskopie.90120125.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Arthroscopically assisted treatment of distal radial fractures combines a closed procedure with conventional techniques . Lower morbidity is the only difference in comparison with open surgery . The main advantage is the possibility of recognizing concomitant injuries and of visualizing the joint surface to be reduced ."
],
"offsets": [
[
0,
321
]
]
}
] |
[
{
"id": "Arthroskopie.90120125.eng.abstr-s1-t1",
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"treatment"
],
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[
26,
35
]
],
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{
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"db_id": "C0039798"
}
]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"fractures"
],
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[
53,
62
]
],
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"db_name": "UMLS",
"db_id": "C0016658"
}
]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s1-t3",
"type": "umlsterm",
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"procedure"
],
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[
81,
90
]
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}
]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s1-t4",
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"techniques"
],
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[
109,
119
]
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]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"morbidity"
],
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[
128,
137
]
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{
"db_name": "UMLS",
"db_id": "C0220880"
},
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}
]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"open"
],
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[
180,
184
]
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{
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}
]
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{
"id": "Arthroskopie.90120125.eng.abstr-s2-t3",
"type": "umlsterm",
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"surgery"
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},
{
"id": "Arthroskopie.90120125.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"injuries"
],
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[
260,
268
]
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{
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}
]
},
{
"id": "Arthroskopie.90120125.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"joint"
],
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[
292,
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]
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{
"db_name": "UMLS",
"db_id": "C0022417"
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]
}
] |
[] |
[] |
[
{
"id": "Arthroskopie.90120125.eng.abstr-s1-r1-t3.1-t1.1",
"type": "conceptual_part_of",
"arg1_id": "Arthroskopie.90120125.eng.abstr-s2-t3",
"arg2_id": "Arthroskopie.90120125.eng.abstr-s3-t1",
"normalized": []
},
{
"id": "Arthroskopie.90120125.eng.abstr-s2-r1-t1.1-t2.1",
"type": "issue_in",
"arg1_id": "Arthroskopie.90120125.eng.abstr-s3-t1",
"arg2_id": "Arthroskopie.90120125.eng.abstr-s3-t2",
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},
{
"id": "Arthroskopie.90120125.eng.abstr-s2-r2-t3.2-t2.1",
"type": "issue_in",
"arg1_id": "Arthroskopie.90120125.eng.abstr-s2-t3",
"arg2_id": "Arthroskopie.90120125.eng.abstr-s3-t2",
"normalized": []
}
] |
Arthroskopie.90120137.eng.abstr
|
Arthroskopie.90120137.eng.abstr
|
[
{
"id": "Arthroskopie.90120137.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Arthroscopy , joint lavage and suction drainage , and open surgery are used in the treatment of knee joint empyema . Between February 1991 and December 1997 , we treated 97 cases arthroscopically . In most cases , the cause of infection was intra-articular injection . Infections after surgical procedures were found in 39 patients . In spite of a clear macroscopical findings , in about one third of the cases the infecting organism could not be found in the synovial fluid culture . During the first operations , the arthroscopy was performed according to the stage of infection : for stage I , only lavage of the knee joint was performed ; for stages II and III , synovectomy was also done . The lavages were performed using separate inflow cannula at least 15 l fluid . At the end of the operations , a collagen-fleece ( Sulmycin Implant ) containing antibiotica was brought into the joint . Systemically , a first generation cephalosporin was given before culture and changed when necessary . The further course was carefully observed postoperatively . Depending on the course and laboratory findings such as WBC , ESR , and CRP , the indication and timing for further revisions were made . In most cases , second-look operations 5-7 days after the first ones were planned . Depending on the course , further operations were also performed . If necessary , partial synovectomy , removal of fibrin clots and adhesions , and additional lavage were performed during the second examination . After that , intra-articular instillation of 160-320 mg gentamycin ( Refobacin ) was performed . Also during the second examination , synovial fluid cultures were taken to find the infecting organism ."
],
"offsets": [
[
0,
1694
]
]
}
] |
[
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Arthroscopy"
],
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[
0,
11
]
],
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"db_id": "C0003904"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"joint"
],
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[
14,
19
]
],
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{
"db_name": "UMLS",
"db_id": "C0022417"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"lavage"
],
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[
20,
26
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022100"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"suction"
],
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[
31,
38
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038638"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"drainage"
],
"offsets": [
[
39,
47
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013103"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"open"
],
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[
54,
58
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0266061"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"surgery"
],
"offsets": [
[
59,
66
]
],
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{
"db_name": "UMLS",
"db_id": "C0038894"
},
{
"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"treatment"
],
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[
83,
92
]
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"db_id": "C0039798"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"knee"
],
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[
96,
100
]
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"db_id": "C0022742"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"joint"
],
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[
101,
106
]
],
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"db_name": "UMLS",
"db_id": "C0022417"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t11",
"type": "umlsterm",
"text": [
"empyema"
],
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[
107,
114
]
],
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"db_name": "UMLS",
"db_id": "C0014009"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t12",
"type": "umlsterm",
"text": [
"suction drainage"
],
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[
31,
47
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038638"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s1-t13",
"type": "umlsterm",
"text": [
"knee joint"
],
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[
96,
106
]
],
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{
"db_name": "UMLS",
"db_id": "C0022745"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"cause"
],
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[
218,
223
]
],
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{
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"db_id": "C0015127"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"infection"
],
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[
227,
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]
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},
{
"id": "Arthroskopie.90120137.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"injection"
],
"offsets": [
[
257,
266
]
],
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"db_name": "UMLS",
"db_id": "C0021485"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"intra-articular injection"
],
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[
241,
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]
],
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"db_id": "C0021488"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"Infections"
],
"offsets": [
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269,
279
]
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"id": "Arthroskopie.90120137.eng.abstr-s4-t2",
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"text": [
"surgical"
],
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286,
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{
"id": "Arthroskopie.90120137.eng.abstr-s4-t3",
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"procedures"
],
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[
295,
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],
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"patients"
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{
"id": "Arthroskopie.90120137.eng.abstr-s4-t5",
"type": "umlsterm",
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"surgical procedures"
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286,
305
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},
{
"id": "Arthroskopie.90120137.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"findings"
],
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368,
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},
{
"id": "Arthroskopie.90120137.eng.abstr-s5-t2",
"type": "umlsterm",
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"organism"
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"db_id": "C0029235"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"culture"
],
"offsets": [
[
475,
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]
],
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},
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"db_name": "UMLS",
"db_id": "C0010453"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"synovial fluid"
],
"offsets": [
[
460,
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]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0039097"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t1",
"type": "umlsterm",
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"operations"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"arthroscopy"
],
"offsets": [
[
519,
530
]
],
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"db_name": "UMLS",
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}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t3",
"type": "umlsterm",
"text": [
"stage"
],
"offsets": [
[
562,
567
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0027646"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t4",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
571,
580
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t5",
"type": "umlsterm",
"text": [
"stage"
],
"offsets": [
[
587,
592
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027646"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t6",
"type": "umlsterm",
"text": [
"knee"
],
"offsets": [
[
616,
620
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022742"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t7",
"type": "umlsterm",
"text": [
"joint"
],
"offsets": [
[
621,
626
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022417"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t8",
"type": "umlsterm",
"text": [
"stages"
],
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[
647,
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]
],
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"db_id": "C0027646"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s6-t9",
"type": "umlsterm",
"text": [
"knee joint"
],
"offsets": [
[
616,
626
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0022745"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"separate"
],
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728,
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]
],
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"db_id": "C0086972"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"cannula"
],
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]
],
"normalized": [
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"db_id": "C0520453"
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]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"operations"
],
"offsets": [
[
792,
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]
],
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"db_name": "UMLS",
"db_id": "C0543467"
},
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"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s8-t2",
"type": "umlsterm",
"text": [
"collagen-fleece"
],
"offsets": [
[
807,
822
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009325"
}
]
},
{
"id": "Arthroskopie.90120137.eng.abstr-s8-t3",
"type": "umlsterm",
"text": [
"joint"
],
"offsets": [
[
888,
893
]
],
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] |
Arthroskopie.90120144.eng.abstr
|
Arthroskopie.90120144.eng.abstr
|
[
{
"id": "Arthroskopie.90120144.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report on ten patients with idiopathic non-traumatic hemarthrosis of the knee . Arthroscopic evaluation showed various bleeding sources . Besides vascular abnormalities ( e.g. , hemangioma ) or meniscus lesions we found signs of bleeding from severe degenerative osteochondral lesions . Surgical therapy , mostly with arthroscopy , led to good results ."
],
"offsets": [
[
0,
356
]
]
}
] |
[
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"patients"
],
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17,
25
]
],
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{
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}
]
},
{
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],
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68
]
],
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}
]
},
{
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"knee"
],
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[
76,
80
]
],
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},
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"evaluation"
],
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106
]
],
"normalized": [
{
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}
]
},
{
"id": "Arthroskopie.90120144.eng.abstr-s3-t1",
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"abnormalities"
],
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171
]
],
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]
},
{
"id": "Arthroskopie.90120144.eng.abstr-s3-t2",
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"hemangioma"
],
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[
181,
191
]
],
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}
]
},
{
"id": "Arthroskopie.90120144.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"signs"
],
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[
223,
228
]
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},
{
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298
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},
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"therapy"
],
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299,
306
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}
]
},
{
"id": "Arthroskopie.90120144.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"arthroscopy"
],
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[
321,
332
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003904"
}
]
}
] |
[] |
[] |
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] |
Arthroskopie.90120148.eng.abstr
|
Arthroskopie.90120148.eng.abstr
|
[
{
"id": "Arthroskopie.90120148.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Popliteal arteriovenous fistula following knee surgery is a very rare complication . Reviewing the literature , only few such cases are mentioned following tibial head osteotomy , total knee arthroplasty or arthroscopy . We report the case of a 31-year-old man suffering from a pulsatile mass in the poplitea fossa 1 week after arthroscopic resection of the posterior horn of the medial meniscus . Colour-Doppler sonography and angiography revealed a popliteal arteriovenous fistula about 4 months after arthroscopy . After dissection of the fistula and reconstruction of the popliteal artery and vein , the patient's complaints were promptly relieved . The literature covering vascular complications and their incidence in arthroscopy is reviewed"
],
"offsets": [
[
0,
747
]
]
}
] |
[
{
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"fistula"
],
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[
24,
31
]
],
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},
{
"id": "Arthroskopie.90120148.eng.abstr-s1-t2",
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"knee"
],
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[
42,
46
]
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{
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"surgery"
],
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47,
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]
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},
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}
]
},
{
"id": "Arthroskopie.90120148.eng.abstr-s1-t4",
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"complication"
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70,
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"id": "Arthroskopie.90120148.eng.abstr-s1-t5",
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"arteriovenous fistula"
],
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[
10,
31
]
],
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"literature"
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"head"
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"osteotomy"
],
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}
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"knee"
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186,
190
]
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}
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},
{
"id": "Arthroskopie.90120148.eng.abstr-s2-t5",
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"arthroplasty"
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191,
203
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],
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186,
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],
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180,
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{
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],
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},
{
"id": "Arthroskopie.90120148.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"posterior"
],
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[
358,
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]
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},
{
"id": "Arthroskopie.90120148.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"horn"
],
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368,
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]
],
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},
{
"id": "Arthroskopie.90120148.eng.abstr-s3-t4",
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{
"id": "Arthroskopie.90120148.eng.abstr-s4-t5",
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"arteriovenous fistula"
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[
461,
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"id": "Arthroskopie.90120148.eng.abstr-s5-t1",
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"id": "Arthroskopie.90120148.eng.abstr-s5-t3",
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}
] |
[] |
[] |
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"id": "Arthroskopie.90120148.eng.abstr-s5-r7-t5.1-t1.1",
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}
] |
Arthroskopie.90120151.eng.abstr
|
Arthroskopie.90120151.eng.abstr
|
[
{
"id": "Arthroskopie.90120151.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Isolated avulsion fracture of the lesser tuberosity of the humerus is a very rare injury . Diagnosis is often not found right away . In comparison with the literature , the presented case shows the importance of exact anamnesis and physical examination in finding the right diagnosis . Late surgical treatment with endoscopic evaluation of possible attendant injuries can also be useful , as shown in the following case ."
],
"offsets": [
[
0,
421
]
]
}
] |
[
{
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],
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[
18,
26
]
],
"normalized": [
{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s1-t2",
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"humerus"
],
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[
59,
66
]
],
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{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s1-t3",
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"text": [
"injury"
],
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[
82,
88
]
],
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{
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},
{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s2-t1",
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"text": [
"Diagnosis"
],
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[
91,
100
]
],
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{
"db_name": "UMLS",
"db_id": "C0011900"
},
{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s3-t1",
"type": "umlsterm",
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"literature"
],
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[
156,
166
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],
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{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s3-t2",
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"exact"
],
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[
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217
]
],
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"anamnesis"
],
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[
218,
227
]
],
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{
"db_name": "UMLS",
"db_id": "C0021055"
}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s3-t4",
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[
268,
273
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}
]
},
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"diagnosis"
],
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274,
283
]
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{
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},
{
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}
]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"physical examination"
],
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[
232,
252
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],
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}
]
},
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]
},
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326,
336
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]
},
{
"id": "Arthroskopie.90120151.eng.abstr-s4-t4",
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},
{
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291,
309
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{
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"db_id": "C0543467"
}
]
}
] |
[] |
[] |
[
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},
{
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},
{
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},
{
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{
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},
{
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{
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},
{
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},
{
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"type": "associated_with",
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},
{
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},
{
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"type": "associated_with",
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},
{
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},
{
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},
{
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},
{
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},
{
"id": "Arthroskopie.90120151.eng.abstr-s4-r8-t3.1-t4.2",
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}
] |
Arthroskopie.90120161.eng.abstr
|
Arthroskopie.90120161.eng.abstr
|
[
{
"id": "Arthroskopie.90120161.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In cases of anterior shoulder instability it is mandatory to differentiate between traumatic and atraumatic instability . The traumatic instability is characterized by three lesions which are caused at the time of the primary dislocation : ( 1 ) Bankart lesion , ( 2 ) Hill-Sachs lesion , and ( 3 ) overstretching of the capsule . The capsule has to be considered in close relationship to the appearance of the Bankart lesion . The stronger the capsule the greater the external force has to be to surmount the resistance caused by the capsule . The greater the external force , the greater the shearing forces are on the glenoid rim and the greater the damage is to the glenoid rim . Damage to the glenoid rim makes it possible to draw conclusions about the condition of the capsule . The Bankart lesion can be classified into five types : ( 1 ) minimal or no Bankart lesion , ( 2 ) Broca-Hartmann lesion , ( 3 ) step-like , detached labrum lesion , ( 4 ) avulsion fracture , and ( 5 ) chisel fracture . According to the investigation of 100 shoulders with recurrent anterior shoulder dislocation , in 8% the Bankart lesion extended from 6 to 8 o ' clock ( left shoulder ) , in 34% from 6 to 9 o ' clock , in 40% from 6 to 11 o ' clock and in 15% from 6 to 12 o ' clock or beyond these marks . Only in 3% was there no Bankart lesion . When stabilizing a shoulder two criteria have to be taken into consideration : stability and function . A balance has to be found between the two criteria . Reattachment of the labrum alone will not guarantee stability ; the overstreched capsule also has to be shortened or shifted . Two criteria are decisive for the success of the stabilizing operation : ( 1 ) The capsule has to be reattached firmly and watertight all over the anterior glenoid rim ; and ( 2 ) the overstreched capsule has to be shifted or shortened . A comparison between 100 shoulders operated on arthroscopically and 110 operated on according to open Bankart repair has shown that good results concerning stability and function can be obtained with both techniques . The recurrence rate was slightly lower in the open group compared to the arthroscopic group . This study has also shown that excellent function increases the recurrence rate slightly independently of open or closed technique ."
],
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Arthroskopie.90120166.eng.abstr
|
Arthroskopie.90120166.eng.abstr
|
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"The object of this study was to evaluate retrospectively the value of open and arthroscopic procedures at mid-term and long-term follow-up . During the period from January 1980 to June 1997 we performed 247 open ( technique : 134 according to Eden-Hybbinette-Lange , 46 according to Weber , 26 according to Putti-Platt , 41 according to Bankart ) and 76 arthroscopic ( transglenoidal Morgan technique ) shoulder stabilization procedures . The mean follow-up for techniques was : Eden-Hybbinette-Lange 11.1 years ( 2.9-16.7 years ) , Weber 5.2 years ( 2.1-13.0 years ) , Putti-Platt 7.2 years ( 2.2-10.6 years ) , Bankart 1.6 years ( 0.5-3.2 years ) , and Morgan 3.5 years ( 2.8-5.1 years ) . We observed that the classic open Bankart procedure has superior results according to the criteria redislocation , range of motion , sports activity , and arthrosis in comparison with the other open procedures . The results shows that nonanatomical , reconstructive , open procedures are not up to date . The open Bankart procedure reconstructs the pathology of the anterior glenoid rim only . The classic open Bankart procedure seems to be the \" gold standard \" in open shoulder surgery today . The high redislocation rate of the arthroscopic procedure warrants a more stringent patient selection in the future ."
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[] |
[] |
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Arthroskopie.90120171.eng.abstr
|
Arthroskopie.90120171.eng.abstr
|
[
{
"id": "Arthroskopie.90120171.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Baker , Norlin , Hintermann and Arciero have described the arthroscopic findings in first-time traumatic anterior shoulder dislocation ( FTASD ) in a homogeneously aged population . There is no report of arthroscopic findings in other age groups , taking into consideration the time elapsed from the initial traumatic episode . A prospective study of 48 patients suffering a complete FTASD have been arthroscopically examined and documented . Arthroscopy was performed within 6 weeks of the traumatic episode ( group 1 ) or subacutely after 6 weeks in case of persistent pain and apprehension ( group 2 ) . To study the effect of age , patients were divided between those under and those over 32 years of age . All groups demonstrated high numbers of laberal detachments . Group 1 shows no instances of labral destruction and the lowest rate of labral substance lesions ( 40% ) . However , this group revealed the highest rate of IGHL detachment ( insertion site ) , Hill-Sachs-Lesions and glenoid rim defects . There was a significant difference in IGHL substance lesion between acute ( group 1 ) and subacute ( group 2 ) cases ( P = 0.0485 ) as well as in IGHL scar formation ( P = 0.0052 ) . Group 2 also showed a statistical higher rate of labrum destruction ( P = 0.078 ) . Patients older than 32 years showed the highest percentage of partial and complete rotator cuff tears and rotator interval biceps pully lesions . To the best of our knowledge this is the first study which documents the arthroscopic intraarticular pathology in cases of FTASD , also taking into account patient age and time interval from injury . Although patient numbers were small , certain trends appear to emerge . Young patients with FTASD show high percentages of labrum and IGHL detachment , whereas substance defects in these structures were low . Persistent pain and apprehension after initial dislocation appears to be related to substance lesions of the labrum and of IGHL ( group 2 ) . As anticipated , more and marked rotator cuff lesions were found in patients > 32 than in patients = 32 years . An unexpectedly high rate of partial rotator cuff lesions ( 25% ) was detected in patients = 32 years ."
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] |
Arthroskopie.90120189.eng.abstr
|
Arthroskopie.90120189.eng.abstr
|
[
{
"id": "Arthroskopie.90120189.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The application of laser energy to joint capsular tissues resulted in the reduction of the joint capsule . Primary clinical results of combined laser-assisted capsular shrinkage ( LACS ) and multiple suture repair ( Caspari ) for arthroscopic stabilization procedure of anterior shoulder instability are presented . From July 1997 to October 1998 , 18 patients ( 2 female , 16 male ; mean age 27.9 years ; range 16-42 years ) with anterior instability and recurrent dislocations of the shoulder received a combined arthroscopic stabilization procedure . The operative technique involved the use of transglenoid sutures to repair the labrum and shift the capsule ( Caspari ) and LACS . Laser energy was applied using a Ho : YAG laser ( 10 W , 1 J , 10 pulses/s , total energy : 1500-2000 J ) . The patients were followed for an average of 9 months ( range 4-20 months ) . From June 1992 to Februrary 1996 , arthroscopic suture stabilization without laser shrinkage was performed on 17 patients ( 2 female , 15 male ; age 25.9 years/range 18-37 years ) . The average follow-up in this group was 4.5 years ( range 2-5 . 5 years ) , and we found 41.2% ( 7/17 ) recurrent dislocations . After combined arthroscopic procedure of multiple suture repair ( Caspari ) and LACS , a significantly ( chi-squared test , P = 0.05 ) lower recurrence rate was obtained . Only in one patient ( 5.6% , 1/18 ) did we find this failure . No complications occurred in either group . The combination of arthroscopic LACS and Caspari's technique of multiple suture repair in cases of posttraumatic anterior shoulder instability and recurrent dislocations is promising . Although , no long-term results are available , the method seems to be suitable for associating low recurrence rates with the advantages of arthroscopic surgery ."
],
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0,
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}
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Arthroskopie.90120194.eng.abstr
|
Arthroskopie.90120194.eng.abstr
|
[
{
"id": "Arthroskopie.90120194.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Bioabsorbable implants have been advocated for use in arthroscopic repair of unstable shoulders . These implants have been thought to be safe and to have few adverse effects . However , similar implants have been shown to cause nonspecific granulomatous reactions when implanted into bone or soft tissues in studies in both animals and human beings . This retrospective study reports the adverse effects of these implants in five patients who had arthroscopic repair of unstable shoulder . All patients reported increasing pain and loss of shoulder motion , following a symptom-free interval of an average of 2 weeks after insertion of these devices . Two of them required a further arthroscopic lavage and de-bridement to reduce the intracapsular synovitis . Granulomatous reactions were identified histologically in all cases . Three patients were treated conservatively . In all cases an open Bankart repair was required after recurrent dislocation within 1 year ."
],
"offsets": [
[
0,
967
]
]
}
] |
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86,
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] |
[] |
[] |
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}
] |
Arthroskopie.90120198.eng.abstr
|
Arthroskopie.90120198.eng.abstr
|
[
{
"id": "Arthroskopie.90120198.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Insufficiency after anterior cruciate ligament ( ACL ) reconstruction is a typical complication . Between 1 January 1992 and 31 December 1997 a total of 604 operations at the ACL were performed in the traumatology department of Nuremberg hospital . During the same period 48 \" transplant failures \" were treated . There were various reasons for the failure of the transplant , some of them technical , occurring during the operation or during aftercare . Another reason for a re-rupture of the transplant was by trauma . The different reasons for the failure of the transplant were analysed in our patient population . The 48 patients were classified into five groups depending on the primary operation and the means of treatment ( I = ACL sutures , II = artificial ligament , III = semitendinosus tendon , IV and V = ipsi- or contralateral bone-patellar-bone graft harvest after ACL reconstruction ) , so that the different ways of treatment were better comparable . Of the 48 patients 36 were followed up over an average of 2 1/2 years using the Lysholm scores and the OAK scores . The total score of the 36 patients was 81 points and can be valued as good using the evaluation scale of Lysholm and Gillquist . Using the OAK score we found an average of 71 to 81 points in the different groups ; results in the group with the ipsilateral bone-tendon-bone graft harvest after ACL reconstruction were the worst . The totalscore using the OAK score was 74 points and was considered \" moderate \" . The score results were discussed and compared with the current literature ."
],
"offsets": [
[
0,
1571
]
]
}
] |
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"ligament"
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] |
[] |
[] |
[
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{
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{
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{
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{
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] |
Arthroskopie.90120215.eng.abstr
|
Arthroskopie.90120215.eng.abstr
|
[
{
"id": "Arthroskopie.90120215.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Arthrofibrosis represents a severe complication of trauma and surgery around joints with loss of motion due to an excessive fibrotic response in the repair process . Patients with primary arthrofibrosis suffer from a general fibrotic healing response after injury or surgery , while patients with secondary arthrofibrosis exhibit loss of motion due to a local fibrotic healing response . Nonisometric positioning of cruciate ligament grafts , notch impingement or hardware problems may lead to secondary arthrofibrosis . In contrast , the etiology of primary arthrofibrosis is still unknown . There are alterations of the extracellular matrix with an increase in collagen type VI expression similar to other local or systemic fibrotic disorders . A chronic inflammatory process may play a crucial role in the mechanism of primary arthrofibrosis and may indicate an immune response . This immune response may activate inflammatory cells and stimulate resident cells to proliferate and to form extracellular matrix . We still do not know which stimuli trigger the fibrotic response . It may be reasonable to assume that primary arthrofibrosis is an independent disease while secondary arthrofibrosis represents a true complication of trauma and surgery around joints ."
],
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[
0,
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]
]
}
] |
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Arthroskopie.90120233.eng.abstr
|
Arthroskopie.90120233.eng.abstr
|
[
{
"id": "Arthroskopie.90120233.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In most cases total knee arthroplasty is a powerful tool in the treatment of final stage diseases of this joint . However , some patients complain of postoperative pain , swelling , and loss of range of motion . Noninvasive diagnosis often does not reveal an appropriate cause and is insufficient in terms of treatment . Magentic resonance imaging is not available for technical reasons . Thus , invasive procedures are required . In these cases arthroscopy has proved to be of value . The common causes of postoperative dysfunction are arthrofibrosis , impingement due to soft tissue , patellar instability , infection , loosening and wear , and breakdown of implants . The authors demonstrate and discuss diagnostic and therapeutic possibilities by arthroscopy in respect of the literature ."
],
"offsets": [
[
0,
793
]
]
}
] |
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Arthroskopie.90120246.eng.abstr
|
Arthroskopie.90120246.eng.abstr
|
[
{
"id": "Arthroskopie.90120246.eng.abstr-passage-0",
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"text": [
"Arthrofibrosis represents an important complication of anterior cruciate ligament surgery , resulting in postoperative pain and loss of motion . Various pre- , intra- , and postoperative measures have been shown to reduce the incidence of arthrofibrosis . Preoperative measures include the delay of surgery until the inflammatory phase after the initial trauma has been resolved , a physical therapy program and patient selection and counseling . Intraoperative measures focus on correct tunnel placement , aided by arthroscopic and radiological control for graft impingement and avoiding knee strain during final graft fixation . Postoperative measures include a brace-free rehabilitation program , with initial passive hyperextension and early range-of-motion exercises . Regular clinical examinations should be performed to detect loss of motion problems early and initiate appropriate treatment . In the authors ' experience arthrofibrosis can be prevented if these recommendations are followed ."
],
"offsets": [
[
0,
1000
]
]
}
] |
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] |
Arthroskopie.90120252.eng.abstr
|
Arthroskopie.90120252.eng.abstr
|
[
{
"id": "Arthroskopie.90120252.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Arthrofibrosis of the knee may be a localized or generalized condition . The localized forms are cylops tumors , hypertrophic cruciate grafts due to notch-impingement , and intra- or extraarticular adhaesions . These problems can usually be managed by limited , arthroscopic procedures . Generalized arthrofibrosis is caused by a diffuse inflammatory reaction of the knee with fibrosis of the anterior fat pad and the parapatellar retinaculae and contracture of the posterior capsule . Treatment should include open resection of the dense fibrotic tissue , replacing the fat pad and parts of the anterior retinaculae . In addition , open posterior capsulotomy allows for complete extension of the knee . A total of 115 cases have been treated by the authors , and the results of 53 are reported ."
],
"offsets": [
[
0,
796
]
]
}
] |
[
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],
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22,
26
]
],
"normalized": [
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}
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},
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"forms"
],
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87,
92
]
],
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}
]
},
{
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],
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104,
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]
],
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},
{
"id": "Arthroskopie.90120252.eng.abstr-s2-t3",
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],
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Arthroskopie.90120260.eng.abstr
|
Arthroskopie.90120260.eng.abstr
|
[
{
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"text": [
"Most reports in the literature on the timing of anterior cruciate ligament ( ACL ) reconstruction are retrospective . The majority of the authors propose delayed surgery of 4-6 weeks postinjury . In the present study , 45 consecutive ACL reconstructions performed within 2 weeks after injury are documented prospectively . The objective was to evaluate the rate of arthrofibrosis and to detect whether there is a difference between very early ( 3 days after injury ) and early ( 4-14 days after injury ) reconstructed knees . In group A ( \" very early \" ) , 88% of the patients were available for final clinical examination after a mean follow up of 12.6 months . In group B ( \" early \" ) , 90% of the patients were seen after a mean follow-up of 11.6 months . The overall ( n = 40 ) rate of arthrofibrosis was 7.5% ; for group A ( n = 22 ) the rate was 4.5% and for group B ( n = 18 ) 11% . There was no statistically significant difference between the groups comparing the following parameters : Duration of physical therapy and sick leave , manual Lachman testing , KT-1000 measurements , Lysholm score , and IKDC score . Although the difference was not statistically significant , the results regarding the activity level at follow-up are medically important : In group A , 77% of the patients had the same activity level compared to the preoperative status and 23% were less active . In group B , 61% showed the same activity level at follow-up and 39% a lower one . We conclude that in group A the late results in activity level are better and the incidence of arthrofibrosis is lower ( 4.5% ) than for the patients operated on between 4 and 14 days after injury ( arthrofibrosis rate 11% ) . We therefore suggest that early ACL surgery should be performed within 3 days after injury . In all other cases we recommend delayed ACL reconstruction after an interval of over 4-6 weeks , since the incidence of arthrofibrosis in group B was higher ( 11% ) than in the existing literature on delayed ACL reconstruction ."
],
"offsets": [
[
0,
2020
]
]
}
] |
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[] |
[] |
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Arthroskopie.90120268.eng.abstr
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Arthroskopie.90120268.eng.abstr
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"The development of minimally invasive and arthroscopic techniques as well as early rehabilitation has brought a significant increase in the functional outcome of joint mobility following knee surgery . Despite this fact , surgeons are still being confronted with an increasing number of knee operations in patients suffering from limited knee motion or arthrofibrosis . Several surgical techniques to improve knee mobility can be performed , depending on the amount and characteristics of immobility . Indications for arthoscopic or open surgery should be based on an algorhithm . The goal of this paper is to present this algorhithm and discuss the limitations of arthroscopic procedures . In seven patients with an average range of motion of 42.8 ° preoperatively , an open procedure had to be performed . The average range of motion intraoperatively was 115 ° and 97.8 ° at follow-up after 22.4 months ."
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},
{
"id": "Arthroskopie.90120268.eng.abstr-s7-r1-t1.1-t2.1",
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{
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}
] |
Arthroskopie.90120294.eng.abstr
|
Arthroskopie.90120294.eng.abstr
|
[
{
"id": "Arthroskopie.90120294.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The clinical application of cartilage repair procedures is currently being discussion . To define cartilage lesions with respect to localization , degree of cartilage damage , size , and etiology we retrospectively reviewed data from 4408 patients who had knee arthroscopies . Chondral lesions were divided into traumatic ( n = 572 , mean age 30.2 years ; 13.2-52.7 years ) and degenerative ( n = 976 , mean age 51.4 years ; 27.1-79.9 years ) lesions . All traumatic cartilage lesions were associated with isolated anterior cruciuate tear . The time interval between injury and arthroscopy was subdivided in patients with acute anterior cruciate ligament tear ( 6 weeks ) or with chronic joint instability ( > 6 weeks ) . Isolated degenerative cartilage lesions were subdivided in patients aged = 40 years and > 40 years . Patients with other associated lesions were excluded . Because we believe that patients with grade III cartilage lesions under the age of 40 years represent the ideal type of patient to receive cartilage or osteochondral transplantation , the data set was analyzed further to characterize these patients . In both groups ( traumatic and degenerative ) the medial femoral condyle and the medial tibial plateau were most affected . Grade III lesions increased in number and size in all compartments with age by about 2-3 . 5-fold . The medial tibial plateau showed a significantly higher alteration of about 13-fold in patients aged > 40 years . The two subgroups comprising acute and chronic anterior cruciate ligament tears did not demonstrate any statistically significant differences in any parameter . Potential candidates for cartilage grafting accounted for 82 patients ( 5.3% ) on the medial femoral condyle and for 33 patients ( 2.1% ) on the medial tibial plateau of all cartilage lesions ( n = 1548 in this data set . In conclusion , we found no relationship between time of surgery and degree of traumatic cartilage lesions after anterior cruciate ligament tear . The development of grade III cartilage lesions in patients older than 40 years was significantly higher on the medial tibia plateau than in the other compartments . That means that extrinsic factors have more influence on the cartilage damage than genetically determined factors . In respect to the observation that most of the patients achieve a total knee arthroplasty because of osteoarthritis on the medial compartment , all cartilage reconstructive procedures should be focused on the medial compartment ."
],
"offsets": [
[
0,
2507
]
]
}
] |
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},
{
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},
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},
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}
] |
Arthroskopie.90120299.eng.abstr
|
Arthroskopie.90120299.eng.abstr
|
[
{
"id": "Arthroskopie.90120299.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In the treatment of anterior cruciate ligament reconstruction , bone-patellar-tendon-bone allograft has been developed to a standard . Fixation of the graft with interference screws in the femur and/or with staple in the tibia are usual . ALL-PRESS-FIT fixation makes an implant-free acl-reconstruction possible . The bone-patellar-tendon-bone allograft is harvested with oversized bone blocks . The \" Bone-Compactor \" is used for modelling the oversized boneblocks for press-fit-fixation in femur und tibia . Implantation can be managed in either an arthroscopic or open procedure . The proximal boneblock is implanted with a sagittal alignment of the tendon . While rotating the distal block 90 ° to medial , a recontruction of anteromedial und posterolateral fascicle is possible . Tension can be controlled after step-by-step fixation proximal and distally with a distalisation of the tibial block at the end . The prominent tibial block will be pressed in on corticalis-niveau with the \" Reconcillation-Hit \" . A femoral or tibial \" Doubleblock-Fixation \" allows a better anatomical reconstruction ."
],
"offsets": [
[
0,
1104
]
]
}
] |
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{
"id": "Arthroskopie.90120299.eng.abstr-s1-t2",
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"anterior"
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20,
28
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"ligament"
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38,
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"standard"
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20,
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"graft"
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"id": "Arthroskopie.90120299.eng.abstr-s2-t3",
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189,
194
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}
]
},
{
"id": "Arthroskopie.90120299.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"tibia"
],
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221,
226
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}
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"femur"
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492,
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{
"id": "Arthroskopie.90120299.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"tibia"
],
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502,
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"id": "Arthroskopie.90120299.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"Implantation"
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510,
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{
"id": "Arthroskopie.90120299.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"open"
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567,
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"id": "Arthroskopie.90120299.eng.abstr-s6-t3",
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"procedure"
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]
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{
"id": "Arthroskopie.90120299.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"tendon"
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653,
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}
]
},
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"id": "Arthroskopie.90120299.eng.abstr-s9-t1",
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"distalisation"
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868,
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}
]
},
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"id": "Arthroskopie.90120299.eng.abstr-s11-t1",
"type": "umlsterm",
"text": [
"anatomical"
],
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1077,
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"db_id": "C0220784"
}
]
}
] |
[] |
[] |
[
{
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"type": "location_of",
"arg1_id": "Arthroskopie.90120299.eng.abstr-s6-t3",
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"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s1-r2-t4.1-t1.1",
"type": "location_of",
"arg1_id": "Arthroskopie.90120299.eng.abstr-s2-t4",
"arg2_id": "Arthroskopie.90120299.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s1-r3-t4.1-t1.1",
"type": "evaluation_of",
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},
{
"id": "Arthroskopie.90120299.eng.abstr-s1-r5-t3.1-t4.1",
"type": "developmental_form_of",
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},
{
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},
{
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},
{
"id": "Arthroskopie.90120299.eng.abstr-s1-r9-t4.1-t3.1",
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},
{
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"type": "surrounds",
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"arg2_id": "Arthroskopie.90120299.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s1-r11-t3.1-t1.1",
"type": "developmental_form_of",
"arg1_id": "Arthroskopie.90120299.eng.abstr-s6-t3",
"arg2_id": "Arthroskopie.90120299.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s2-r1-t1.1-t3.1",
"type": "developmental_form_of",
"arg1_id": "Arthroskopie.90120299.eng.abstr-s11-t1",
"arg2_id": "Arthroskopie.90120299.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s2-r2-t3.1-t1.1",
"type": "surrounds",
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},
{
"id": "Arthroskopie.90120299.eng.abstr-s2-r3-t1.1-t4.1",
"type": "developmental_form_of",
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"arg2_id": "Arthroskopie.90120299.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s2-r4-t4.1-t1.1",
"type": "surrounds",
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},
{
"id": "Arthroskopie.90120299.eng.abstr-s6-r1-t2.1-t1.1",
"type": "result_of",
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"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s6-r2-t3.1-t1.1",
"type": "measurement_of",
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"normalized": []
},
{
"id": "Arthroskopie.90120299.eng.abstr-s6-r3-t1.1-t2.1",
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"arg2_id": "Arthroskopie.90120299.eng.abstr-s6-t2",
"normalized": []
}
] |
Arthroskopie.90120305.eng.abstr
|
Arthroskopie.90120305.eng.abstr
|
[
{
"id": "Arthroskopie.90120305.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In recent years ACL reconsruction with the midpatellar tendon has been being called into question more and more because of high morbidity at the harvest site and problems with fixation near the joint . The \" wiper effect \" or \" bungee-effect \" may be mentioned as an example . In this paper , ACL reconstruction using the hamstrings is presented , which , in contrast to fixation with the Endobutton , has a very high pull out strength and also tibial fixation near the joint with a biodegradable interference screw . This surgical method has been carefully developed and is technically sophisticated . The technique can be used mainly in younger women with small patellae , athletically inactive persons with a high level of instability , all patients with parapatellar problems or pain , and patients whose occupation involves kneeling . The short-term results are excellent ; long-term results with this new method are not yet available . This method should be seen as an alternative to ACL reconstruction with the midpatellar tendon and , in our view , the security of fixation is at least as good as with the Endobutton ."
],
"offsets": [
[
0,
1126
]
]
}
] |
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"morbidity"
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}
]
},
{
"id": "Arthroskopie.90120305.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"joint"
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194,
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{
"id": "Arthroskopie.90120305.eng.abstr-s3-t2",
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"contrast"
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{
"id": "Arthroskopie.90120305.eng.abstr-s3-t3",
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"joint"
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},
{
"id": "Arthroskopie.90120305.eng.abstr-s3-t4",
"type": "umlsterm",
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"screw"
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"surgical"
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"method"
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}
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},
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"technique"
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}
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},
{
"id": "Arthroskopie.90120305.eng.abstr-s5-t2",
"type": "umlsterm",
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"women"
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},
{
"id": "Arthroskopie.90120305.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"patellae"
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},
{
"id": "Arthroskopie.90120305.eng.abstr-s5-t4",
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{
"id": "Arthroskopie.90120305.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"parapatellar"
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"db_id": "C0030563"
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},
{
"id": "Arthroskopie.90120305.eng.abstr-s5-t7",
"type": "umlsterm",
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"pain"
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] |
[] |
[] |
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] |
Arthroskopie.90120313.eng.abstr
|
Arthroskopie.90120313.eng.abstr
|
[
{
"id": "Arthroskopie.90120313.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Since 1993 , 30 patients with acute intraarticular distal radius fractures have been treated under arthroscopic assistance . In 12 patients ( 40% ) concomitant lesions of the intrinsic scapholunate ligaments were diagnosed . According to Geissler we found grade I-tear in one patient , grade II in three , grade III in six and grade IV in two patients . The eight individuals with grade III-and IV-lesions additionally revealed marked instablity intraoperatively . Therefore , operative stabilization was subsequently performed by temporary scapholunate and scaphocapitate arthrodesis . Seven patients out of this group ( 87.5% ) were followed up clinically and radiologically 3 years postoperatively , on average . Clinical examination included range of motion tests and a subjective questionnaire concerning pain and working ability . Objective grip strength was measured using a Jamar tester and compared to the contralateral wrist . Radiological evaluation consisted of the posteroanterior and lateral view as well as stress views in radial and ulnar deviation . Data were evaluated by the Jakim and Cooney scoring system as well as the demerit point system by Gartland and Werley as modified by Sarmiento et al. According to Gartland , 100% of our patients showed an excellent result ; these rates were 86% using the Jakim score and 60% using the Cooney scoring system . According to the subjective questionnaire all of the patients revealed an excellent or good result ."
],
"offsets": [
[
0,
1476
]
]
}
] |
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] |
[] |
[] |
[
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] |
Arthroskopie.90120318.eng.abstr
|
Arthroskopie.90120318.eng.abstr
|
[
{
"id": "Arthroskopie.90120318.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Displacement of the discus articularis with and without repositioning represents a common pathological alteration of the temporomandibular joint ( tmj ) . The primary clinical symptoms are pain and reduced jaw movement . Particularly in cases of long-term complaints , conservative treatment methods such as splint and physiotherapy often do not produce the desired results . For these patients , arthroscopy combined with lysis and lavage is the treatment of choice for diagnostic as well as therapeutic purposes . In our department we performed this surgery on a total of 23 patients with discus displacement . With this low-risk procedure we achieved a definite improvement in symptoms in 20 patients ; 11 of those patients were eventually complaint-free . Additionally , we can report a general improvement in opening the mouth . Except for a slight postoperative soft-tissue swelling , no complications developed . Thus , we can conclude that arthroscopic lysis and lavage , a low-risk and minimally invasive procedure , should be preferred to open arthrotomy in the primary treatment of tmj-displacements ."
],
"offsets": [
[
0,
1112
]
]
}
] |
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] |
[] |
[] |
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] |
Bundesgesundheitsblatt.00430011.eng.abstr
|
Bundesgesundheitsblatt.00430011.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430011.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The laboratory surveillance of measles in Germany contributes to an objective estimation of the situation . Compared to data of the pre-vaccination era , the incidence of measles has been reduced , while a shift in age towards the group of 15-year-olds is observed . Germany will have considerable difficulties to reach the aim of eradicating measles in the European region by the year 2007. Apart from the fact that systematic surveillance is lacking , the immunity gaps in small children represent a particularly weak spot . In order to effectively control measles , high vaccination rates of at least 90% are necessary by the end of the second year of life . In addition , laboratory surveillance has to be included to measure successful vaccination . Main focusses are the laboratory confirmation of suspected measles cases , seroprevalence studies of population immunity as well as the control of the circulation of measles viruses . The Working Group Measles ( \" Arbeitsgemeinschaft Masern \" - AGM ) as well as the amended law on infection prevention are important instruments to make measurable progress towards measles eradication also in Germany . We report on the activities of the National Reference Centre for Measles , Mumps and Rubella since 1991. The German data are compared to those of selected other European countries ."
],
"offsets": [
[
0,
1338
]
]
}
] |
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"measles"
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31,
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{
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Bundesgesundheitsblatt.00430022.eng.abstr
|
Bundesgesundheitsblatt.00430022.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430022.eng.abstr-passage-0",
"type": "abstract",
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434
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] |
[] |
[] |
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Bundesgesundheitsblatt.00430033.eng.abstr
|
Bundesgesundheitsblatt.00430033.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430033.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recently , there has been intensive research on the use of electromagnetic waves and high pressure for the treatment of food with the aim of minimal processing . The methodological approach is , on the one hand , to achieve a rapid heating of the product by avoiding high temperature gradients which is possible e.g. by using microwaves under appropiate conditions . On the other hand , attempts are made to use so-called non-thermal effects which can be obtained e.g. by using high electric fields pulses or high hydrostatic pressure . It is obvious that the stage of development of the respective procedures is different and that further information is needed conserning safety of the treated food , in particular of that treated with non-thermal procedures . Moreover , the mechanisms of action requires further elucidation ."
],
"offsets": [
[
0,
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]
}
] |
[
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[] |
[] |
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Bundesgesundheitsblatt.00430131.eng.abstr
|
Bundesgesundheitsblatt.00430131.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430131.eng.abstr-passage-0",
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"text": [
"The German drug market offers thymus preparations , among other agents , for treatment of rheumatic diseases . The published data on thymus products are based on case reports , on studies with inadequate and partly ethically questionable design and on investigations that were too short and comprised too few patients to allow scientific valid conclusions . Therefore , reflecting the current status of scientific knowledge , and in consideration of the risks possibly associated with the use of thymus preparations for treatment of rheumatic diseases ( e.g. rheumatoid arthritis ) , there is no medical substantiation for a recommendation of this therapy ."
],
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0,
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}
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[] |
[] |
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Bundesgesundheitsblatt.00430190.eng.abstr
|
Bundesgesundheitsblatt.00430190.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430190.eng.abstr-passage-0",
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"The assessment of health related quality of life is increasingly accepted in medicine . Health related quality of life can be viewed as self-report relating to psychological , social , physical and every day life components of well-being and function as perceived by the person . To measure health related quality of life several assessment instruments have been developed and psychometrically tested , are available internationally . One of those instruments is the originally American SF-36 which assesses with 36 items eigth dimensions of subjective health as well as two summary scores ( a short form with 12 items , the SF-12, exists , too ) . The instrument was translated into several languages , psychometrically tested and normed in more than ten countries , also in Germany . Translating and psychometric testing of the German SF-36 complied with the international guidelines ( IQOLA-Group ) . In several healthy and ill population excellent psychometric properties concerning reliability , validity and sensitivity were found . In the meantime international work with the SF-36 has proceeded , also in Germany the instrument is frequently used . Currently a health economical derivate of the SF-36, the SF-6D, originally developed in England , as well as computerized applications , computer adaptive testing and evaluation of the item relevance in comparison to other health related quality of life instruments are being performed . The SF-36 is one of the most prominent instrument to assess health related quality of life , even though it has been criticised for focussing on functional conceptualizations of quality of life . The coming years will show which role the SF-36 plays in comparison to other instruments in assessing health related quality of life in medicine ."
],
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0,
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Bundesgesundheitsblatt.00430198.eng.abstr
|
Bundesgesundheitsblatt.00430198.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430198.eng.abstr-passage-0",
"type": "abstract",
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"While health-related quality of life of adults is increasingly researched , the quality of life of healthy and chronically ill children and adolescents has only recently been addressed . The present paper analyses published articles on children's health-related quality of life , identified from medical and psychological sources according to focus and methodology in research . The review shows that empirical work is short and describes available instruments for the assessment of quality of life in children . Increased research activities are necessary to include quality of life assessment of children in prevention , public health , treatment evaluation and rehabilitation ."
],
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0,
680
]
]
}
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] |
[] |
[] |
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] |
Bundesgesundheitsblatt.00430210.eng.abstr
|
Bundesgesundheitsblatt.00430210.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430210.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Within the framework of the National Health Interview and Examination Survey 1998 the Short Form Questionnaire SF-36 has been applied to measure the health related quality of life ( HRQOL ) . This opened more opportunities than simply creating a new normative sample for the German adult population . Thus , the very complex interdependence between morbidity , satisfaction , risk factors , health related behaviours , social status , age and sex on the one side and the subjective assessment of health related quality of life on the other hand may be investigated . First results of the Survey data are presented which open the discussion of the possibilities and limits of the SF-36 instrument for measuring health related quality of life at the population level ."
],
"offsets": [
[
0,
766
]
]
}
] |
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36
]
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],
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]
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Bundesgesundheitsblatt.00430328.eng.abstr
|
Bundesgesundheitsblatt.00430328.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430328.eng.abstr-passage-0",
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"text": [
"In the way risk issues in environmental and health protection politics are handeled , a great discrepancy is obvious between scientifically based , well established quantitative risk assessment procedures on one side and the perception of risk in the society on the other . One reason for this is the insufficient participation of relevant concerned societal groups in all procedures of risk assessment and standard setting in the health related environmental protection . Based on five postulates , the acceptable risk as a theoretical basis for regulations in health and environmental protection will be developed . Starting point of the determination of an acceptable risk is a public discourse about the way the society is willing to handle risk issues . All relevant concerned groups within the society should have a fair chance of participation . Risk assessment and standard setting only get their democratic authorisation by fair participation ."
],
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0,
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[] |
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Bundesgesundheitsblatt.00430336.eng.abstr
|
Bundesgesundheitsblatt.00430336.eng.abstr
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[
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"An almost bewildering number of widely differing methods and techniques , often not validated , are being applied often inappropriately in the field of environmental medicine to answer questions regarding exposure assessment , diagnosis , treatment , counselling and prevention . Therefore quality control within the field of environmental medicine is quite problematic . A primary goal of the newly formed RKI-Commission \" Methods and Quality Assurance in Environmental Medicine \" is to form a panel of experts in the field , who evaluate the situation and generate consensus documents containing respective recommendations . By this the commission will contribute to standardization and agreement on appropriate methods , procedures and their correct application in the practice of environmental medicine . Hopefully it will also achieve a stronger , more consistent use of evidence-based-medicine and improve the quality of the structure , processes and results of research and practice in this field . The committee will initially deal with the issue of clinical environmental medicine , because here the largest problems in quality assurance are seen . In this context the commission work look at the problem areas of environmental-medical outpatient units and environmental clinics . The work of the commission will be supported by the newly formed Documentation and Evaluation Center for Methods in Environmental Medicine ( Zentrale Erfassungs- und Bewertungsstelle fuer umweltmedizinische Methoden , ZEBUM ) at the Robert Koch Institute ."
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Bundesgesundheitsblatt.00430343.eng.abstr
|
Bundesgesundheitsblatt.00430343.eng.abstr
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],
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[] |
[] |
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Bundesgesundheitsblatt.00430346.eng.abstr
|
Bundesgesundheitsblatt.00430346.eng.abstr
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"The area \" Environment and Health \" is characterized by interdisciplinary features and , consequently , an intense need for communication . In addition it has to be considered that sometimes there are difficulties in terms of information search . A comparison of national problem solving strategies concerning electronic network activities within this area led to the development project for a European information and communication platform . By this electronic platform the international exchange of experiences , coordination of activities , harmonization efforts and an optimization of qualification possibilities for environmental health professionals will become easier ."
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Bundesgesundheitsblatt.00430360.eng.abstr
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Bundesgesundheitsblatt.00430360.eng.abstr
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Bundesgesundheitsblatt.00430400.eng.abstr
|
Bundesgesundheitsblatt.00430400.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430400.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The results of the German National Health Interview and Examination Survey 1998 confirm allergies as widespread diseases in Germany . In total 40 to 43 % of the adult population have or have had an allergic disease . The morbidity was assessed using a self-administered questionnaire and a personal interview performed by a physician . The agreement between questionnaire and interview data is greater than 90 % for allergic rhinitis , food allergy and urticaria and about 80 % for contact dermatitis and asthma . The results of both assessment methods showed remarkable differences between East and West Germany . Using the interview data 17 % of the West but only 11 % of the East German adults have/had e.g. an allergic rhinitis . Comparable differences exist for contact dermatitis . Many people with allergies suffer or have suffered from several allergies . Frequent patterns of combination are food allergy/allergic rhinitis and asthma/allergic rhinitis . In comparison with former studies we observed an increase of 70 % in the prevalence of allergic rhinitis between 1990/92 and 1998. The relative increase is higher in East than in West . The time trend in prevalence of asthma could only be calculated for the West German population . The results show a remarkable increase here , too ."
],
"offsets": [
[
0,
1297
]
]
}
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Bundesgesundheitsblatt.00430415.eng.abstr
|
Bundesgesundheitsblatt.00430415.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430415.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The data of the National Health Interview and Examination Survey provides information about the prevalence of cardiovascular risk factors in the population living in Germany . The survey consists of a health oriented questionnaire and an examination of 7124 persons from a representative sample of the 18 to 79 year-old population . Even using strict criteria for each risk factor in order to avoid overestimating the number of subjects at risk , the results show an alarmingly high dissemination of risk factors among the population . Thus one third of the 18 to 79 year-old men and women got cholesterol levels > = 250 mg/100 ml . Obesity , i . e . a body mass index > = 30 kg/m2 is prevalent in one of five persons . More than half of the overweight , over 50-year-old women , show an abdominal fat distribution , which is an additional factor to the risks in question . 18% of the men and women show a \" moderate \" to \" severe \" hypertension ( as defined by the WHO criterias ) . More than 20% of the 20 to 49 year-old men are heavy smokers with a daily consumption of > = 20 cigarettes a day . Only one third of all 18 to 79 years old do not have any of the risk factors , as there are daily smoking , hypercholesterolemia , obesity and hypertension ( the last terms defined as mentioned above ) . About 40% show one factor , ca. 20% two factors . There is a strong dependence between the distribution of the risk factors and the socio-economic level . For women , an increase of the total risk has been shown over the last years ."
],
"offsets": [
[
0,
1536
]
]
}
] |
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] |
[] |
[] |
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{
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] |
Bundesgesundheitsblatt.00430424.eng.abstr
|
Bundesgesundheitsblatt.00430424.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430424.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Pain is a widely occurring disturbance of well-being and has serious consequences for the quality of life of patients suffering from acute or chronic pain . Thus , pain makes high demands on the health system . For the first time in the Federal Republic of Germany the National Health Interview and Examination Survey allows to make representative statements concerning the prevalence of pain , its intensity , frequency , duration and localisation . Furthermore , the results enable to differentiate according to age , gender , and social classes . The SF-36, used as an instrument to measure health related quality of life , has been employed to demonstrate the overwhelming significance of pain for the well-being of the population . In this publication the connection between certain disease syndromes like migraine and arthrosis and the prevalence of different qualities of pain is investigated . Additional more complex evaluation of the epidemiological data on pain are in preparation ."
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"arg1_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-t7",
"arg2_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-r6-t7.1-t4.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-t7",
"arg2_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-r7-t1.1-t4.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s7-t1",
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{
"id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-r8-t7.1-t3.1",
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"arg2_id": "Bundesgesundheitsblatt.00430424.eng.abstr-s6-t3",
"normalized": []
}
] |
Bundesgesundheitsblatt.00430432.eng.abstr
|
Bundesgesundheitsblatt.00430432.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-passage-0",
"type": "abstract",
"text": [
"More than 2/3 of German adults are using seeing aids . Individuals who are wearing eyeglasses are consulting their opthalmic practitioner about every 3rd year while persons with contact lenses see their practitioner every 2nd year . Almost only people under age 40 are buying contact lenses . The market for spectacles is very large for consumers older than 45 years since hypermetropia is mainly corrected with eyeglasses in this age group . The prevalence of hard of hearing is 8% for adults and is increasing with age , but only 2,5% of the study population are equipped with hearing aids . The distribution between males and females is 59% vs. 41% for hard of hearing . 12,4% of the interviewed persons report a handicap . There are regional and gender-specific differences . The proportion of handicapped person raises with increasing age and counts of diseases ."
],
"offsets": [
[
0,
868
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"adults"
],
"offsets": [
[
24,
30
]
],
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{
"db_name": "UMLS",
"db_id": "C0001675"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"aids"
],
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[
48,
52
]
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"db_name": "UMLS",
"db_id": "C0021588"
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"eyeglasses"
],
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[
83,
93
]
],
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{
"db_name": "UMLS",
"db_id": "C0015421"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"persons"
],
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[
165,
172
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027361"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"lenses"
],
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[
186,
192
]
],
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{
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"db_id": "C0023308"
},
{
"db_name": "UMLS",
"db_id": "C0023317"
},
{
"db_name": "UMLS",
"db_id": "C0023318"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"contact lenses"
],
"offsets": [
[
178,
192
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009836"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"people"
],
"offsets": [
[
245,
251
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027361"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"age"
],
"offsets": [
[
258,
261
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001792"
},
{
"db_name": "UMLS",
"db_id": "C0001811"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"lenses"
],
"offsets": [
[
284,
290
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023308"
},
{
"db_name": "UMLS",
"db_id": "C0023317"
},
{
"db_name": "UMLS",
"db_id": "C0023318"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"contact lenses"
],
"offsets": [
[
276,
290
]
],
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{
"db_name": "UMLS",
"db_id": "C0009836"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"market"
],
"offsets": [
[
297,
303
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024826"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"spectacles"
],
"offsets": [
[
308,
318
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015421"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"older"
],
"offsets": [
[
347,
352
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0331059"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"hypermetropia"
],
"offsets": [
[
373,
386
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020490"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"eyeglasses"
],
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412,
422
]
],
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t6",
"type": "umlsterm",
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"age"
],
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431,
434
]
],
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"db_name": "UMLS",
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},
{
"db_name": "UMLS",
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s4-t7",
"type": "umlsterm",
"text": [
"age group"
],
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431,
440
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027362"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"prevalence"
],
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[
447,
457
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220900"
},
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"db_name": "UMLS",
"db_id": "C0033105"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"hard"
],
"offsets": [
[
461,
465
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018599"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"hearing"
],
"offsets": [
[
469,
476
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018767"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"adults"
],
"offsets": [
[
487,
493
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"age"
],
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517,
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},
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"population"
],
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550,
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]
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"db_name": "UMLS",
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t7",
"type": "umlsterm",
"text": [
"hearing"
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},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t8",
"type": "umlsterm",
"text": [
"aids"
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t9",
"type": "umlsterm",
"text": [
"hearing aids"
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579,
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s5-t10",
"type": "umlsterm",
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"hard of hearing"
],
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461,
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"distribution"
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"db_name": "UMLS",
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"males"
],
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]
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"db_name": "UMLS",
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t3",
"type": "umlsterm",
"text": [
"females"
],
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629,
636
]
],
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"db_name": "UMLS",
"db_id": "C0086287"
},
{
"db_name": "UMLS",
"db_id": "C0015780"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t4",
"type": "umlsterm",
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"hard"
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656,
660
]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t5",
"type": "umlsterm",
"text": [
"hearing"
],
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664,
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]
],
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s6-t6",
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"text": [
"hard of hearing"
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656,
671
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],
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"persons"
],
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699,
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]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s9-t1",
"type": "umlsterm",
"text": [
"handicapped"
],
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{
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"person"
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{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s9-t3",
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}
]
},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s9-t4",
"type": "umlsterm",
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"diseases"
],
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858,
866
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
}
] |
[] |
[] |
[
{
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{
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{
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{
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{
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{
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},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-r10-t3.3-t3.1",
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},
{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s2-r11-t4.1-t3.3",
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{
"id": "Bundesgesundheitsblatt.00430432.eng.abstr-s3-r1-t4.1-t3.1",
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{
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"arg2_id": "Bundesgesundheitsblatt.00430432.eng.abstr-s9-t2",
"normalized": []
},
{
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}
] |
Bundesgesundheitsblatt.00430443.eng.abstr
|
Bundesgesundheitsblatt.00430443.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430443.eng.abstr-passage-0",
"type": "abstract",
"text": [
"To improve the insufficient vaccination rates of the general population in Germany , general practitioners play an important role as mediators . In actual practice , doctor's receptionists often have to control the certificates of vaccination and advise the patients . Therefore , in the offices for public health in Trier and Wittlich training courses were held . At the beginning the knowledge of the 102 participants was measured by a questionnaire . Results show that even those doctor's receptionists , who were very interested in vaccinations , had insufficient knowledge and to some part alarmingly few vaccinations themselves , especially to protect them against Influenza and Hepatitis B."
],
"offsets": [
[
0,
697
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.00430443.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"vaccination"
],
"offsets": [
[
28,
39
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042196"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430443.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"population"
],
"offsets": [
[
61,
71
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032659"
}
]
},
{
"id": "Bundesgesundheitsblatt.00430443.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"Germany"
],
"offsets": [
[
75,
82
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0017480"
}
]
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[] |
[] |
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Bundesgesundheitsblatt.00430449.eng.abstr
|
Bundesgesundheitsblatt.00430449.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430449.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Data for HIV infection on transmission probabilities per contact are of widely differing quality . Estimates of infection probabilities after sexual exposures are the most problematic , even though sexual exposure is the most frequent transmission risk . Extrapolations of data from discordant couple cohort studies and from US seroincidence studies may be seriously biased . Infectivity of and susceptibility to HIV may be influenced by concomitant STDs , antiretroviral therapy , alloimmunization and/or subinfectious virus exposures and thus may show a wide range of inter- and intraindividual variability . Differences in factors influencing transmission probability of HIV most likely outweigh differences in sexual behaviour in explaining the differences in epidemic spread of HIV ."
],
"offsets": [
[
0,
788
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]
}
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{
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] |
[] |
[] |
[
{
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Bundesgesundheitsblatt.00430839.eng.abstr
|
Bundesgesundheitsblatt.00430839.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430839.eng.abstr-passage-0",
"type": "abstract",
"text": [
"With the institution of the Protection against infection Act , case definitions will be officially introduced for the routine transmission of notifiable infectious diseases from local health departments to state and national health institutions in Germany for the first time . Case definitions link the disease entity with a defined description of the disease . The abstraction thereby required leads to the creation of nosological entities . The case definitions , which were developed by the Robert Koch Institute ( RKI ) according to the Protection against infection Act , enable the local health departments to assess and categorise reported cases , deaths and laboratory reports of pathogens according to uniform criteria prior to transmission to the RKI via the state health institutions . The quality of surveillance data will be significantly improved , as each reported case/infection will fulfil defined criteria , thereby enabling unclear cases/diagnoses to be separated from those that are confirmed ."
],
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[
0,
1013
]
]
}
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] |
[] |
[] |
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{
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{
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{
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{
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{
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{
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}
] |
Bundesgesundheitsblatt.00430870.eng.abstr
|
Bundesgesundheitsblatt.00430870.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430870.eng.abstr-passage-0",
"type": "abstract",
"text": [
"With the new Protection against infection Act , the system of notifiable diseases in Germany will have a new basis . In the future , certain diseases will be reportable by physicians and laboratory confirmed results for certain pathogens will be reportable by laboratories . The law clearly lays out which information has to be passed along with the report by the reporting physician or laboratory . It also states which parts of this information can be transmitted further on by the local health departments . Particularly for reports of suspected diseases or for laboratory results , not all the information which the health department should transmit will be available with the first report . Thus , the local health departments have to conduct own investigations . The local health departments have the task to join the report of a disease and a laboratory result concerning one person and transmit it as a single case . In order to facilitate this task of putting together all transmittable data , surveillance case definitions were developed and a defined data entry program will be provided . The data will be transmitted via the respective State authority to the Robert Koch-Institut ."
],
"offsets": [
[
0,
1193
]
]
}
] |
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] |
[] |
[] |
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Bundesgesundheitsblatt.00430875.eng.abstr
|
Bundesgesundheitsblatt.00430875.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430875.eng.abstr-passage-0",
"type": "abstract",
"text": [
"According to the former notification procedures , most notifiable infectious diseases ( with the exception of HIV ) were reported to the local health authorities . With the institution of the new Protection against infection Act ( IPA ) the diagnosis of a number of infectious pathogens will be reported anonymous directly to the Robert Koch Institute ( RKI ) . These mandatory notifications refer to the diagnosis of Treponema pallidum , HIV , Echinococcus sp . , Plasmodium sp . , Rubellavirus ( only connatal infections ) and Toxoplasma gondii ( only connatal infections ) . The head of the facility conducting the diagnostic test ( laboratory ) is responsible for the carrying out of the notification . In order to obtain all information required in the notification , the physician , who is sending in the material for testing , is required by law , to support the person responsible for carrying out of the notification by supplying the necessary data . First , the laboratory fills out the notification form with all the available information and sends the original to the RKI . Then , together with the test results , a copy of the notification is sent to the physician who initiated the diagnostic test . The physician completes any missing data in the form and sends this copy to the RKI . By doing so the physician has fulfilled his obligation to support the notification process . This new reporting system will yield better data about infectious pathogens that do not require direct intervention by the local health authorities . In order to obtain reliable data , it is important that all physicians support the notification process ."
],
"offsets": [
[
0,
1648
]
]
}
] |
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Bundesgesundheitsblatt.00430882.eng.abstr
|
Bundesgesundheitsblatt.00430882.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430882.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Important prerequisites for the successful implementation of vaccination programs exist in Germany . However , vaccination coverage is not sufficient neither in children nor in adults . The new Protection against infection Act will improve both the surveillance of the morbidity due to vaccine preventable diseases and the surveillance of vaccination coverage and it's improvement . The new law also underscores the responsibility of the public health service for the information of the population about the benefits of vaccination programs ."
],
"offsets": [
[
0,
542
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] |
[] |
[] |
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}
] |
Bundesgesundheitsblatt.00430887.eng.abstr
|
Bundesgesundheitsblatt.00430887.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430887.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Hospitals and clinics for ambulant surgery shall identify and register certain officially defined nosocomial infections ( Surveillance ) as well as the isolation of bacteria with special and important antimicrobial resistancies ( § 23 Abs. 1 IfSG = Infection Prevention Act ) . The nosocomial infections to be recorded , i . e device associated infections and postsurgical woundinfections , have been selected on the basis of national and international experiences with the surveillance of nosocomial infections . Important antimicrobial resistancies have been determined according to both the prevalence of the bacteria in nosocomial settings as well as their clinical and epidemiological importance . Most of the relevant data may be provided by the clinical microbiology laboratory but shall be collected , listed and discussed by the staff of wards or surgery clinics . Both types of documentation shall be used to identify and eradicate problems in hygiene management and to stop further distribution of difficult to treat bacteria like MRSA . They are part of the quality assurance management according to § 137 SGB V."
],
"offsets": [
[
0,
1124
]
]
}
] |
[
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0,
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{
"id": "Bundesgesundheitsblatt.00430887.eng.abstr-s1-t2",
"type": "umlsterm",
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"surgery"
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Bundesgesundheitsblatt.00430891.eng.abstr
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Bundesgesundheitsblatt.00430891.eng.abstr
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[
{
"id": "Bundesgesundheitsblatt.00430891.eng.abstr-passage-0",
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"text": [
"Patients infected with viral haemorrhagic fevers ( VHF ) , pneumonic plague or zoonotic orthopoxvirus infections usually require intensive care and a special isolation . Contact persons must be traced and monitored . Last year our working group published a concept for the management and control of these life-threatening highly contagious diseases . Now the principles of our plan have been accepted . The development of guidelines for rapid reaction to those communicable diseases is an important task for all EU Member States . In Germany microbiological diagnosis is performed by a diagnostic centre ( Biosafety-Level BSL4) and supported by a corresponding confirmation laboratory . At present four high security infectious disease units for patient care ( HSIU ) are available in Munich , Leipzig , Hamburg and Berlin . Another one located in Frankfurt will be functional by 2001. In addition to the HSIU a corresponding number of centres of competence shall be established in order to support and advise the hospitals initially treating the patients as well as the local public health officer . The risk categorisation for contact persons , which has been developed by our working group , has proved to be very useful in practice . Ambulances should be used for transfer of patients to the HSIU . So-called transport-isolators are not suitable for patients who are seriously ill. Air-based transport without using an isolator is a problem , since no decontamination procedure exists . As soon as the last HSIU in the Rhine Main area is working the centres of competence will be established . This will provide competent health care for VHF-patients and a convincing management for these kinds of threats to public health everywhere in Germany ."
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Bundesgesundheitsblatt.00430900.eng.abstr
|
Bundesgesundheitsblatt.00430900.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430900.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Germany's new Protection against infection Act ( Infektionsschutzgesetz ) will take effect on January 1 , 2001. It will result in an increase of notifications on reportable infections . Counties and states have to adjust the infrastructure of their reportable disease notification systems to meet the demands of the new legislation . An increased demand for human resources at the non-medical staff level is anticipated . Continuing education programs for medical and non-medical staff at public health offices are mandatory . Physicians in private practice , hospitals and diagnostic laboratories and leaders of nursing homes are target groups for special information . A timely review and epidemiological evaluation of all notifications forwarded by county health offices has to be performed at the state level . This is a prerogative for immediate response in case of non-localized increases in reported disease incidence . The author advocates the development of an epidemiological rapid reaction scheme ( epidemiological fire brigade ) in which public health physicians at the county , state , and federal level cooperate in a gradual response to outbreak situations according to actual demand ."
],
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[
0,
1200
]
]
}
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[] |
[] |
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] |
Bundesgesundheitsblatt.00430905.eng.abstr
|
Bundesgesundheitsblatt.00430905.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.00430905.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The IfSG will facilitate notifications for medical practitioners and doctors in hospitals , laboratories and institutes of pathology . According to the IfSG doctors treating patients have to consider only 18 instead of 40 notifiable communicable diseases whose majority will be acute viral hepatitis , measles and tuberculosis . Doctors in laboratories have to consider as new notifiable pathogens only adenovirus in conjunctival smears , measles virus and Legionella sp . In the local health offices the handling of case definitions , collection of more variables per case and electronic data-processing has to be learned . These new tools are indispensable to achieve better quality of data in order to reach better descriptive epidemiology and targeted interventions . Last but not least notifying doctors themselves and public health institutions will derive benefit from this . Doctors will accept their obligation to notify communicable diseases only if they receive timely and regularly qualified and interesting feedback ."
],
"offsets": [
[
0,
1030
]
]
}
] |
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] |
[] |
[] |
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}
] |
Bundesgesundheitsblatt.0043s009.eng.abstr
|
Bundesgesundheitsblatt.0043s009.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-passage-0",
"type": "abstract",
"text": [
"HIV remains infectious at room temperature for about six to twelve hours under sterile conditions , the time is shorter in the presence of bacteria and when clotting occurs . HIV infectivity is easily destroyed by disinfectants . The human infectious dose of HIV is around 100 to 1000 particles , dependent on the virus and the site of entry into the host . After inoculation new HIV is produced after 24 hours , and HIV has spread over the whole organism by the end of one or two weeks . HIV infection may be detected after four to twelve weeks by antibody assays , and after eleven days by nucleic acid based assays . Anti-HIV production might be slowed down under initial therapy ."
],
"offsets": [
[
0,
684
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"HIV"
],
"offsets": [
[
0,
3
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019682"
}
]
},
{
"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"temperature"
],
"offsets": [
[
31,
42
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039476"
},
{
"db_name": "UMLS",
"db_id": "C0005903"
}
]
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[] |
[] |
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"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s5-r23-t4.1-t8.1",
"type": "interacts_with",
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"arg2_id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s5-t8",
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},
{
"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s6-r1-t1.1-t2.1",
"type": "conceptual_part_of",
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"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s6-r2-t2.1-t1.1",
"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s6-t2",
"arg2_id": "Bundesgesundheitsblatt.0043s009.eng.abstr-s6-t1",
"normalized": []
}
] |
Bundesgesundheitsblatt.0043s013.eng.abstr
|
Bundesgesundheitsblatt.0043s013.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The risk of occupational infection with HIV is subjectively often overestimated . This is in contrast to the fact , that other viral infections are more frequent and contagious . In medical services Hepatitis B is now the most frequent occupational viral infection . Prevention of infection is the most important measure . The \" Unfallverhuetungs-Vorschriften \" of the \" Berufsgenossenschaft \" are giving advices how to work in medical services to prevent infections . Another important issue are vaccinations . There is a clear recommendation for hepatitis B vaccination in health care workers . After contamination of unvaccinated health care workers with suspicious materials for hepatitis B an active and passive immunisation is demanded . For the case of hepatitis C there does not exist medical post-exposure-prophylaxis . The early intervention with Interferon after establishing the diagnosis of acute hepatitis C seems to have a high efficacy ."
],
"offsets": [
[
0,
953
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-t1",
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"risk"
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4,
8
]
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-t2",
"type": "umlsterm",
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"infection"
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34
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}
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"HIV"
],
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[
40,
43
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{
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}
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"risk of"
],
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[
4,
11
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],
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}
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"contrast"
],
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[
93,
101
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],
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{
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"viral"
],
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[
127,
132
]
],
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}
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-t3",
"type": "umlsterm",
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"infections"
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]
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"viral infections"
],
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127,
143
]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"Hepatitis"
],
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[
199,
208
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"viral"
],
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[
249,
254
]
],
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{
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s3-t3",
"type": "umlsterm",
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"infection"
],
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[
255,
264
]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"Hepatitis B"
],
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[
199,
210
]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s3-t5",
"type": "umlsterm",
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"viral infection"
],
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249,
264
]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"Prevention"
],
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[
267,
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]
],
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{
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"db_id": "C0687732"
}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s4-t2",
"type": "umlsterm",
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"infection"
],
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281,
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]
],
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"measure"
],
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s5-t1",
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"infections"
],
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]
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}
]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s6-t1",
"type": "umlsterm",
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"vaccinations"
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]
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t1",
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t2",
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"text": [
"hepatitis"
],
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548,
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]
],
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]
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t3",
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t4",
"type": "umlsterm",
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"health"
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{
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"care"
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t6",
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"workers"
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],
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}
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t7",
"type": "umlsterm",
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]
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-t9",
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"health care workers"
],
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"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t2",
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t3",
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]
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t4",
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t5",
"type": "umlsterm",
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"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t6",
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]
},
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633,
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]
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},
{
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"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s9-t3",
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],
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
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},
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"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t4",
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{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t5",
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],
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019196"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-r1-t3.1-t2.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s1-r2-t2.1-t3.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t2",
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"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-r1-t1.1-t4.1",
"type": "diagnoses",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t1",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t4",
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s2-r2-t1.1-t4.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t1",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s4-r1-t3.1-t1.1",
"type": "conceptual_part_of",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r1-t8.1-t5.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t8",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t5",
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},
{
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"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t6",
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},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r3-t8.1-t3.1",
"type": "performs",
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"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r4-t3.1-t8.1",
"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r5-t5.1-t1.1",
"type": "isa",
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"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r6-t1.1-t8.1",
"type": "occurs_in",
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"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s8-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r7-t5.1-t3.1",
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"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s7-r8-t5.1-t1.1",
"type": "conceptually_related_to",
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"arg2_id": "Bundesgesundheitsblatt.0043s013.eng.abstr-s10-t1",
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},
{
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Bundesgesundheitsblatt.0043s018.eng.abstr
|
Bundesgesundheitsblatt.0043s018.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s018.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In 1998 recommendations for postexposure prophylaxis after occupational and nonoccupational HIV exposure of the Deutsch-Oesterreichische AIDS-Gesellschaften were developed and published . The recommendations describe the risks of HIV-transmission and the indications of postexposure prophylaxis after occupational , sexual and injection drug use HIV exposure . In general , the use of two reverse transcriptase inhibitors ( normally AZT and 3TC ) and one protease inhibitor ( indinavir or nelfinavir ) are recommended . In consideration of individual circumstances other drugs also could be given . The antiretroviral drugs should be taken as soon as possible following exposure . Good efficacy can be expected when drugs are taken within 2 hours after HIV-exposure . During pregnancy , protease inhibitors should not be given . The official recommendations of the Deutsch-Oesterreichische AIDS-Gesellschaften are illustrated and discussed ."
],
"offsets": [
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0,
941
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}
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] |
[] |
[] |
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{
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"type": "affects",
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Bundesgesundheitsblatt.0043s026.eng.abstr
|
Bundesgesundheitsblatt.0043s026.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s026.eng.abstr-passage-0",
"type": "abstract",
"text": [
"It is not clear whether public health insurance will cover post exposure prophylaxis ( PEP ) , whereby the question of costs being covered by private health insurance companies is not taken into consideration here . Regulations concerning prevention ( § 20 SGB V ) , precautionary medical services ( § 23 SGB V ) and health examination ( § 25 SBG V ) offer no legal basis for cost coverage . PEP is patient care in the sense of § 27 SGB V. However , this particular treatment has not yet been adapted into public health insurance financial guidelines because the federal committees have not yet made appropriate recommendations . This should be achieved soon , in order to eliminate legal ambiguities in this area . The principles of the so called \" new methods of examination and treatment \" legal construct may support cost coverage liability . On the whole , however , German-Austrian recommendations concerning indication and use of PEP must be formulated more concretely and unambiguously . If a doctor , in the case of an indication according to the German-Austrian recommendations , does not prescribe PEP , this would probably not be malpractice , because there are still many scientific questions to be answered ."
],
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Bundesgesundheitsblatt.0043s037.eng.abstr
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Bundesgesundheitsblatt.0043s045.eng.abstr
|
Bundesgesundheitsblatt.0043s045.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s045.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In June 1998 the German and Austrian AIDS Clinical Societies issued guidelines on HIV Post-Exposure Prophylaxis ( PEP ) . They provided a standard for consultation and treatment process , including advice on how to proceed in cases of non-nosocomial exposure to HIV . The guidelines were published in scientific and community media . This study aims to asses the impact of national guidelines on demand for and practice of non-nosocomial Post-Exposure Prophylaxis ( NN-PEP ) in Germany . Specialised HIV-practitioners ( n=80), clinics ( n=100) and health services including AIDS service organizations ( n=170) were evaluated regarding demand for and practice of NN-PEP in their institutions during the previous twelve month period . This analysis is based on 100 structured questionnaires . In addition 29 clinical emergency departments and 10 ambulatory emergency services were contacted . They were asked to provide consultation to a man with risk factors that compose an indication for treatment under the current guidelines . One year after establishment of a coherent guideline for NN-PEP in Germany , consultation and treatment practices are well established . 68 institutions provided consultation in 531 cases and a treatment recommendation was given in 143 cases . 75 men and 14 women were treated . Ten of them reported needle-sharing as their exposure risk ( 8 men/2 women ) . In 90.2% treatment was administered within 24 hours of the risk event . Treatment consists of triple-combination therapy ( ten different standards in 40 institutions ) . Viral load measurements ( PCR , bDNA ) are used to assess viral replication . There are different levels of qualification and accessibility , reflecting a specialisation of services . Consultation and treatment are heavily clustered ( e.g. two institutions account for 55.2% of all treatment cases ) . The cost of treatment is 1500,- til 2800,- DM ( 750-1400 Euro ) per case . Specialisation is also found in the qualitative analysis of the interviews . Out of 33 telephone contacts 8 yield a consultation in line with current guidelines . The interviews reveal high barriers to NN-PEP during weekend hours ( Fri 6 p.m. to Sun 12 p.m. ) through ambulatory emergency services . The demand for consultation and treatment in Germany remains to be low in more than 100 institutions . The specialisation of services provides a basis for data collection and evaluation of the cost-effectiveness of NN-PEP . The process of qualification through guidelines does not appear to have been completed . The different practices of treatment and the low use of treatment in the i.v. drug-using population need to be further investigated ."
],
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0,
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}
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] |
Bundesgesundheitsblatt.0043s054.eng.abstr
|
Bundesgesundheitsblatt.0043s054.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.0043s054.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A study is presented where after educative counselling HIV-negative partners of HIV-positive people are provided with an emergency pack of postexposure prophylaxis ( PEP ) medication . This enables them to start a post exposure prophylaxis immediately in a case of HIV exposure and helps to avoid delays until a physician with experience in HIV care can be consulted . The study is aimed to investigate how often HIV exposures occur in serodiscordant couples , whether the availability of PEP increases risk behaviour , whether the individual participants are able to distinguish PEP-justifying exposures from those with a lower risk of transmission , and whether an emergency pack is adequate to enable timely initiation of PEP . 13 participants were recruited so far . Of these , 5 couples were aware of the HIV-serodiscordance at the time the relationship started , while the other 8 found out about the HIV infection of one partner while the relationship was already going on for some time . The first group had a median number of 35 sexual contacts within the last three months prior to the start of the study , whereas the second group had a median number of 3,5 sexual contacts . In the course of the observation which included a cumulative time of 56 patient months , three HIV exposures occured . In two cases PEP was initiated within less than an hour , in one case no medication was taken . Whether the number of risk contacts increases in these couples as a consequence of the availability of PEP medication remains to be seen . The current data support the assumption that an emergency pack is a reasonable and feasible intervention for HIV-serodiscordant couples ."
],
"offsets": [
[
0,
1678
]
]
}
] |
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"prophylaxis"
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"PEP"
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}
] |
[] |
[] |
[
{
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{
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},
{
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{
"id": "Bundesgesundheitsblatt.0043s054.eng.abstr-s3-r1-t9.1-t2.1",
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},
{
"id": "Bundesgesundheitsblatt.0043s054.eng.abstr-s3-r2-t4.1-t5.1",
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{
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"type": "interacts_with",
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},
{
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Bundesgesundheitsblatt.90420095.eng.abstr
|
Bundesgesundheitsblatt.90420095.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420095.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The purpose of the Transfusion Law , which came into force on 7 July 1998 , is to ensure the supply with safe blood products , to reinforce the confidence in the blood transfusion system , and to support self sufficiency with blood and plasma . In order to reach this goal , the law regulates the essential reqirements for the adequate collection of blood and blood constituents , as well for safe usage of blood products . Moreover it lays down rules for look-back procedures , prescribes the collection of data on the epidemiology in donor populations , creates a legal basis for the advisory group ' Arbeitskreis Blut ' , and fosters the self sufficiency with blood and plasma by several prescriptions ."
],
"offsets": [
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0,
706
]
]
}
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[] |
[] |
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}
] |
Bundesgesundheitsblatt.90420105.eng.abstr
|
Bundesgesundheitsblatt.90420105.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420105.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In principle , haematopoietic stem cell preparations offer a paramount array of clinical opportunities and future perspectives . They are the basis for stem cell transplantation , e.g. for rescue of haematopoiesis after high dose cytotoxic therapy , for treatment of immunologic deficiencies and congenital metabolic disorders , and , in the future , a vehicle for gene therapy . Stem cells may be obtained from bone marrow , peripheral blood , or umbilical cord blood . This article provides an overview of the biology of stem cells , procedures for their collection , the legal basis for the manufacture of stem cell preparations , and essential requirements for their marketing authorisation . According to German legislation , stem cell preparations are medicinal products necessitating a marketing authorisation , if they are not produced for a certain ill person , but manufactured beforehand and banked until needed ."
],
"offsets": [
[
0,
924
]
]
}
] |
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}
] |
Bundesgesundheitsblatt.90420113.eng.abstr
|
Bundesgesundheitsblatt.90420113.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420113.eng.abstr-passage-0",
"type": "abstract",
"text": [
"New therapeutic approaches in surgery , transplantation , and cancer therapy make likely that the need for blood and blood components will continue . The development of artificial oxygen carriers for clinical use appears to be desirable , to overcome several problems encountered with human blood and blood products : the risk of transmission of infectious diseases ( which , however is very low meanwhile ) , the need for determination of blood groups and the use of compatible blood , the limited availability of blood donations , and the precautions necessary to store the liable blood components for a limited time . Native stroma free haemoglobin cannot be used as blood substitute . Different approaches to solve the problem of breakdown into dimers of stroma free haemoglobin after injection into circulation have been used . Modification of the haemoglobin-molecule has to be performed , either by crosslinking or conjugation , or by enclosure in encapsulated particles . Several preclinical and clinical trials have been carried out showing different results relating to their indication , efficacy and side effects compared to native blood products . Further investigations will be necessary to develop suitable artificial haemoglobins and to demonstrate their therapeutic value ; so far , the classical donated blood is far from being superseded by artificial blood substitutes ."
],
"offsets": [
[
0,
1390
]
]
}
] |
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] |
Bundesgesundheitsblatt.90420118.eng.abstr
|
Bundesgesundheitsblatt.90420118.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-passage-0",
"type": "abstract",
"text": [
"According to the experience of the German organisations for blood and plasma donation it is very important to increase the willingness to donate blood or plasma by repeated information and motivation campaigns , especially because donations are voluntarily . The campaign called \" Blood and Plasma Donation . Each drop helps \" was initiated as a cooperative campaign of all organisations involved in blood and plasma donation . The goals of the campaign are to give the public insights to the necessity and urgency of blood donation for the intended self-sufficiency , especially for plasma and to gain new donators for the future ."
],
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0,
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"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s4-t5",
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] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r1-t3.1-t4.1",
"type": "surrounds",
"arg1_id": "Bundesgesundheitsblatt.90420118.eng.abstr-s4-t3",
"arg2_id": "Bundesgesundheitsblatt.90420118.eng.abstr-s4-t4",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r2-t3.1-t2.1",
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"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r3-t5.1-t3.2",
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{
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r5-t5.1-t1.2",
"type": "produces",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r6-t1.1-t3.2",
"type": "surrounds",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r7-t1.1-t1.2",
"type": "surrounds",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r8-t5.1-t2.1",
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{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r9-t3.1-t5.1",
"type": "location_of",
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{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r10-t1.1-t4.1",
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"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r11-t1.1-t2.1",
"type": "surrounds",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r12-t1.1-t5.1",
"type": "location_of",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r13-t3.1-t3.2",
"type": "surrounds",
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"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s1-r14-t3.1-t1.2",
"type": "surrounds",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s2-r1-t1.1-t1.2",
"type": "surrounds",
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"arg2_id": "Bundesgesundheitsblatt.90420118.eng.abstr-s3-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s2-r2-t1.1-t2.1",
"type": "surrounds",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s3-r1-t1.1-t1.2",
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},
{
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s3-r3-t1.1-t3.1",
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},
{
"id": "Bundesgesundheitsblatt.90420118.eng.abstr-s4-r2-t2.1-t3.1",
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}
] |
Bundesgesundheitsblatt.90420121.eng.abstr
|
Bundesgesundheitsblatt.90420121.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420121.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Red cells , platelet concentrates and fresh frozen plasma of a single donation contain leucocytes , causing a lot of side effects . Modern filtration- and apheresis-techniques lead to a reduction of residual leucocyte counts of 1x106 per unit . The best method to achieve controlled and validated conditions is the blood bank performed standardised prestorage-filtration . This is an effective method , to prevent cytokine-mediated and leucocyte-mediated febrile nonhaemolytic transfusion reactions ( FNHTR ) , to prevent a primary immunisation to leucocyte- and histocompatibility-antigens , to avoid transmission of viral infections by blood transfusion , e.g. Cytomegalovirus ( CMV ) and to exclude in special cases bacterial septicaemia . In addition , there are references to reduce the postoperative infections , the rate of recurrence of a tumor and the postoperative complications in patients undergoing cardiac surgery . The use of leucocyte-depleted blood components for special indications is meanwhile established . Some European countries have made a decision for a general filtration of all blood components containing leucocytes . The authors recommend the general leucocyte-depletion of blood components considering the German medical law ( AMG ) and cost/benefit ratio ."
],
"offsets": [
[
0,
1287
]
]
}
] |
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{
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{
"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s1-t2",
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{
"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s1-t3",
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"fresh frozen plasma"
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s2-t1",
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s2-t3",
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"leucocyte counts"
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{
"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s3-t3",
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s3-t4",
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s4-t2",
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s4-t3",
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"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s4-t4",
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{
"id": "Bundesgesundheitsblatt.90420121.eng.abstr-s4-t5",
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[] |
[] |
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] |
Bundesgesundheitsblatt.90420132.eng.abstr
|
Bundesgesundheitsblatt.90420132.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420132.eng.abstr-passage-0",
"type": "abstract",
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"Since the publication of a case of Syphilis transmission by blood transfusion in 1915 the discussion about transfusion-associated bacterial infection is ongoing . For some time , virus infections through blood and blood products have been highlighted . However , in the last years the attention required has been drawn to the problem of transmission of bacteria . In this publication the present situation concerning the contamination rates through blood components and the frequency of transfusion-associated microbial infections is outlined . The bacteria involved are discussed . Furthermore , the state of the art for prevention and diagnosis as well as the methods for inactivation of bacteria are assessed ."
],
"offsets": [
[
0,
713
]
]
}
] |
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] |
[] |
[] |
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] |
Bundesgesundheitsblatt.90420150.eng.abstr
|
Bundesgesundheitsblatt.90420150.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420150.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In contrast to the regulations in other European countries , blood components for transfusion are defined by the German Drug Law as medicinal products , for which a national marketing authorisation is required . In the case of blood components , i.e. concentrates prepared from individual donations , official batch release testing , as it is in place for plasma products , is not practicable . Thus during the licensing process the Paul-Ehrlich-Institute has to focus on compliance with the state of the art regarding donor selection and testing , as well as on the assessment of quality by means of testing random samples . The current practice of quality control and the available tests and their value are critically reviewed . There is still a need for development of meaningful and feasible test methods , research in this field is a task also of our group . Moreover , the Paul-Ehrlich-Institute is permanently involved in discussions in relevant national and European expert groups and official bodies with the aim of further improvements of quality and safety of blood components ."
],
"offsets": [
[
0,
1090
]
]
}
] |
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"id": "Bundesgesundheitsblatt.90420150.eng.abstr-s1-t3",
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Bundesgesundheitsblatt.90420187.eng.abstr
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Bundesgesundheitsblatt.90420187.eng.abstr
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[
{
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"The term \" Ecstasy \" includes a group of different methylenedioxyamphetamines which produce hallucinogenic activity , stimulation and the so-called ' entactogenic ' effects . - \" Entactogen \" is usually translated as \" producing a touching within \" or \" creating an internal contact \" and refers to the special psychotropic effect of this substances . Entactogens have been reported to make users aware of previously unconscious feelings and experiences . The \" entactogenic \" effect is the most typical of the psychedelic effects n 3,4-methylenedioxyamphetamine ( MDMA ) . MDMA induces euphoria and acts stimulating , but the most common effect of MDMA is a heightened sense of \" closeness \" with other people . The negative effects , especially depression and a general sense of anxiety , may endure after the acute phase of ecstasy . Ecstasy is not a novel substance . However , the rapid spread connected with the arising techno-scene and the increasing prevalence of ecstasy-use world-wide is unprecedented ."
],
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"db_id": "C0115471"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"prevalence"
],
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[
958,
968
]
],
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"db_name": "UMLS",
"db_id": "C0220900"
},
{
"db_name": "UMLS",
"db_id": "C0033105"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s3-r2-t1.1-t2.1",
"type": "evaluation_of",
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"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s4-r1-t1.1-t2.1",
"type": "interacts_with",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s4-r2-t2.1-t1.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r1-t1.1-t2.1",
"type": "affects",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r2-t1.1-t2.1",
"type": "treats",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r3-t3.1-t2.1",
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"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t3",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r4-t3.1-t1.1",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r5-t3.1-t2.1",
"type": "treats",
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{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s5-r6-t1.1-t3.1",
"type": "interacts_with",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t3",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r1-t3.1-t1.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t3",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r2-t3.1-t1.1",
"type": "diagnoses",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t3",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
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{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r3-t3.1-t2.1",
"type": "affects",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r4-t2.1-t1.1",
"type": "result_of",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r5-t3.1-t2.1",
"type": "treats",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r6-t2.1-t1.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r7-t1.1-t2.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s8-t1",
"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
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},
{
"id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-r8-t1.1-t2.1",
"type": "associated_with",
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"arg2_id": "Bundesgesundheitsblatt.90420187.eng.abstr-s6-t2",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420196.eng.abstr
|
Bundesgesundheitsblatt.90420196.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-passage-0",
"type": "abstract",
"text": [
"To assess the epidemiological situation of salmonellosis in Germany a total of 1608 strains of salmonella sampled in a sentinel-study were isolated and typed . The results on occurrence , distribution , types and antbiotic resistance of salmonella were compared with both the strains forwarded to the National Reference Center ( NRC ) for Salmonellosis for typing from all regions of Germany and the strains notified according to the duty of notification in the five new Laender ( federal countries ) and Berlin ."
],
"offsets": [
[
0,
513
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"salmonellosis"
],
"offsets": [
[
43,
56
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036117"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"Germany"
],
"offsets": [
[
60,
67
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0017480"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"strains"
],
"offsets": [
[
84,
91
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0080194"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"salmonella"
],
"offsets": [
[
95,
105
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036117"
},
{
"db_name": "UMLS",
"db_id": "C0036111"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"sentinel-study"
],
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[
119,
133
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0056838"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"occurrence"
],
"offsets": [
[
175,
185
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243132"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"distribution"
],
"offsets": [
[
188,
200
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0520511"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"antbiotic"
],
"offsets": [
[
213,
222
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003455"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"salmonella"
],
"offsets": [
[
237,
247
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036117"
},
{
"db_name": "UMLS",
"db_id": "C0036111"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"strains"
],
"offsets": [
[
276,
283
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0080194"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"National"
],
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[
301,
309
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015737"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t7",
"type": "umlsterm",
"text": [
"Salmonellosis"
],
"offsets": [
[
339,
352
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036110"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t8",
"type": "umlsterm",
"text": [
"Germany"
],
"offsets": [
[
384,
391
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0017480"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"type": "umlsterm",
"text": [
"strains"
],
"offsets": [
[
400,
407
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0080194"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t10",
"type": "umlsterm",
"text": [
"Berlin"
],
"offsets": [
[
505,
511
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005125"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r1-t5.1-t3.1",
"type": "treats",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r2-t1.1-t3.1",
"type": "result_of",
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},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r3-t4.2-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r4-t5.1-t1.1",
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"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r5-t2.1-t3.1",
"type": "associated_with",
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"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
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},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r6-t2.1-t1.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t2",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r7-t5.1-t1.1",
"type": "diagnoses",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r8-t4.2-t3.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r9-t1.1-t4.2",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r10-t5.1-t3.1",
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"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r11-t5.1-t3.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r12-t3.1-t2.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r13-t5.1-t3.1",
"type": "complicates",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r14-t3.1-t4.2",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r15-t5.1-t3.1",
"type": "diagnoses",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r16-t3.1-t1.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t3",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s1-r17-t1.1-t2.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r1-t1.1-t8.1",
"type": "measurement_of",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r2-t4.1-t5.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r3-t4.1-t1.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"normalized": []
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r5-t4.1-t9.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"normalized": []
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r6-t8.1-t5.1",
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"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"normalized": []
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r7-t1.1-t4.2",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r8-t8.1-t4.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t8",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r9-t1.1-t5.1",
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"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
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{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r10-t4.2-t5.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r11-t5.1-t4.2",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r12-t9.1-t5.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r13-t4.1-t9.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r14-t9.1-t4.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r15-t4.1-t8.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r17-t4.2-t1.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r18-t4.1-t5.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r19-t5.1-t1.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t5",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r20-t1.1-t4.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r21-t8.1-t9.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t8",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-r22-t1.1-t9.1",
"type": "measurement_of",
"arg1_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t1",
"arg2_id": "Bundesgesundheitsblatt.90420196.eng.abstr-s2-t9",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420212.eng.abstr
|
Bundesgesundheitsblatt.90420212.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-passage-0",
"type": "abstract",
"text": [
"According to the EU Regulation on Novel Foods and Novel Food Ingredients , novel foods have to be as safe for the consumer as comparable conventional products . In order to ensure this , they are subjected to a health evaluation , which is performed on a case- by-case basis according to the principle of substantial equivalence , before they are placed on the market . For this purpose , information concerning toxicity , allergenicity and nutritional aspects is needed and in the individual case the requirements depend on the nature of the food as well as on the potential exposure to the consumer ."
],
"offsets": [
[
0,
602
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Regulation"
],
"offsets": [
[
20,
30
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0034982"
},
{
"db_name": "UMLS",
"db_id": "C0220905"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"Foods"
],
"offsets": [
[
40,
45
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016452"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"Food"
],
"offsets": [
[
56,
60
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016452"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"foods"
],
"offsets": [
[
81,
86
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016452"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"health"
],
"offsets": [
[
211,
217
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018684"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"evaluation"
],
"offsets": [
[
218,
228
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220825"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"market"
],
"offsets": [
[
361,
367
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024826"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"toxicity"
],
"offsets": [
[
412,
420
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0600688"
},
{
"db_name": "UMLS",
"db_id": "C0040539"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"nature"
],
"offsets": [
[
529,
535
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0349590"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"food"
],
"offsets": [
[
543,
547
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016452"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s2-r1-t2.1-t3.1",
"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t2",
"arg2_id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-r2-t3.1-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t3",
"arg2_id": "Bundesgesundheitsblatt.90420212.eng.abstr-s3-t1",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420219.eng.abstr
|
Bundesgesundheitsblatt.90420219.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The increasing importance of Lyme-Borreliosis in Saxony was the reason to perform this study with the intention to get information about the infection rate of ticks with Borrelia burgdorferi sensu lato . The infection rate was determined by PCR and testing slide-fixed ticks by immunofluorescence . For this analysis 3234 ticks from Saxony and neighbouring regions were collected and investigated . 252 of 1378 ticks checked by immunofluorescence were positive ( 18,3% ) , 440 of 1856 ticks examined by PCR were infected ( 23,7% ) . 50 ticks with multiple infection by several genospecies of Borrelia burgdorferi were found . The importance of these findings and possible conclusions are discussed ."
],
"offsets": [
[
0,
699
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"intention"
],
"offsets": [
[
102,
111
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0162425"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
141,
150
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"Borrelia"
],
"offsets": [
[
170,
178
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006033"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"Borrelia burgdorferi"
],
"offsets": [
[
170,
190
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006034"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
208,
217
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"PCR"
],
"offsets": [
[
241,
244
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032520"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"testing"
],
"offsets": [
[
249,
256
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039593"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"immunofluorescence"
],
"offsets": [
[
278,
296
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0079603"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"analysis"
],
"offsets": [
[
308,
316
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0002778"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"immunofluorescence"
],
"offsets": [
[
428,
446
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0079603"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"PCR"
],
"offsets": [
[
503,
506
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032520"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
556,
565
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"Borrelia"
],
"offsets": [
[
592,
600
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006033"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"Borrelia burgdorferi"
],
"offsets": [
[
592,
612
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006034"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"findings"
],
"offsets": [
[
650,
658
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-r1-t3.1-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-r2-t4.1-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-r3-t1.1-t4.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s1-r4-t1.1-t3.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r1-t2.1-t1.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r2-t4.1-t1.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t4",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r3-t1.1-t4.1",
"type": "result_of",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r4-t1.1-t3.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r5-t1.1-t2.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r6-t2.1-t3.1",
"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s2-r7-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-r1-t1.1-t2.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-r2-t2.1-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t2",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-r3-t3.1-t1.1",
"type": "causes",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-r4-t1.1-t3.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s6-t1",
"arg2_id": "Bundesgesundheitsblatt.90420219.eng.abstr-s5-t3",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420327.eng.abstr
|
Bundesgesundheitsblatt.90420327.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420327.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The public perception of the importance of environmental factors for carcinogenesis was investigated in a representative sample of Austrians ( n=2073) who in 1995 were > =15 years of age . Results show that about 60% of the respondents attribute great importance to environmental pollution as a cause for cancer development . Only smoking ranks higher . Approximately 56% of the respondents rate toxic agents in the workplace to be of great importance . In the case of pesticide residues this is true for 50% and in the case of passive smoking for 44% . High voltage power lines , ' earth rays ' and ' water veins ' are rated to be of great importance by about 25% of the respondents . The ratings of women and men do not differ except for the last two esoteric factors , with women giving more importance to them . The survey shows that the role of environmental factors in cancer development is overestimated . A better information of the public about the various cancer risks seems to be necessary . It should be based on the recommendations concerning risk communication , risk didactics and risk comparisons ."
],
"offsets": [
[
0,
1114
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420327.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"perception"
],
"offsets": [
[
11,
21
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030971"
}
]
},
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Bundesgesundheitsblatt.90420377.eng.abstr
|
Bundesgesundheitsblatt.90420377.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420377.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Travel medicine in Germany is getting more important , but also more complex in view of increasing worldwide tourism , the unbroken keenness of Germans to travel , new vaccines , changed travel habits and the altered epidemiological situation of several infectious agents . Qualified health information requires extensive specialized knowledge and up-to-date , differentiated information about travel destinations . The quality of the manifold counselling services varies considerably , and it is often difficult for the traveller seeking medical advice to make judgements about the quality of counselling . Possible solutions for the improvement of quality and transparancy in this field are seen - amongst others - in the further development of quality standards , the certification and publication of qualified information and in a closer cooperation between travel agencies , pharmacies and physicians ."
],
"offsets": [
[
0,
907
]
]
}
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[] |
[] |
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] |
Bundesgesundheitsblatt.90420381.eng.abstr
|
Bundesgesundheitsblatt.90420381.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420381.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Persons who cross international boundaries are at increased risk of contracting infectious diseases . An analysis of the reported communicable diseases in Germany shows : A large number of cases of typhoid fever , paratyphoid fever , shigella infections , trichinellosis and brucellosis notified during the last years in Germany originated from foreign countries . Intervention measures are necessary , above all , with regard to gastrointestinal infections and vaccine-preventable diseases ."
],
"offsets": [
[
0,
492
]
]
}
] |
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"Persons"
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0,
7
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{
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{
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"infectious diseases"
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"id": "Bundesgesundheitsblatt.90420381.eng.abstr-s2-t1",
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{
"id": "Bundesgesundheitsblatt.90420381.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"fever"
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{
"id": "Bundesgesundheitsblatt.90420381.eng.abstr-s2-t6",
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{
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}
] |
[] |
[] |
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Bundesgesundheitsblatt.90420389.eng.abstr
|
Bundesgesundheitsblatt.90420389.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420389.eng.abstr-passage-0",
"type": "abstract",
"text": [
"At present , the importation into Germany of life-threatening and highly contagious diseases such as pneumonic plague and Ebola is unlikely , but cannot be ruled out . In spite of the extreme rarity of these diseases , guidelines are necessary to prevent the spread of these agents in case of their importation . In Germany , marked regional differences exist with respect to the development of emergency regulations and the availability of specialized centers for diagnostics and therapy . A federal framework is missing . A concept is presented here in which the capacity to respond is substantially augmented with limited additional cost through inter-regional cooperation using existing infrastructure and federally standardized procedures ."
],
"offsets": [
[
0,
745
]
]
}
] |
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"id": "Bundesgesundheitsblatt.90420389.eng.abstr-s3-t3",
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}
] |
[] |
[] |
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Bundesgesundheitsblatt.90420408.eng.abstr
|
Bundesgesundheitsblatt.90420408.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420408.eng.abstr-passage-0",
"type": "abstract",
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"Considering its frequency and fatality rate dengue fever repesents the most important tropical virus infection . Several millions of infected people including thousands of German tourists are recorded annually . Due to the increase of insect populations and intercontinental travelling the four dengue serotypes nowadays can be found worldwide . Sequential dengue fever infections have been reported to occur with increasing severity . Secondary infections , which are also found in tourists , may be associated with hemorrhagic fever and may be life- threatening , especially in children . During primary infection , a laboratory diagnosis can be made by detecting both IgM- and IgG-antibodies . The serotype involved can be identified by PCR . Dengue fever-like symptoms can also be caused by a variety of parasitic or virus infections . Although a specific therapy is not available , intravenous infusions may be of vital importance during dengue hemorrhagic fever ."
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[] |
[] |
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Bundesgesundheitsblatt.90420412.eng.abstr
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Bundesgesundheitsblatt.90420412.eng.abstr
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Bundesgesundheitsblatt.90420471.eng.abstr
|
Bundesgesundheitsblatt.90420471.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420471.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In a retrospective study examination- and spermiogram-data were collected from 3821 men . The data came from the vicinity of the andrological department of the Leipzig university-clinic . It should be examined , whether first-examined patients without anamnestic or abnormal clinical findings did show a deterioration of the sperm-quality within the examination-years 1985 to 1996. Furtheron information should be collected concerning a possible dependence of the spermiogram data from the year of birth . Within the group of the 25 to 34 year old men ( n=1650) in the time frame from 1985 until 1996 the absolute sperm count of 195 millions changed to 138 millions , the sperm concentration of 79,7 was reduced to 52,6 Mio/ml and the fraction of morphological normal sperm was diminished from 64,6% to 59,6% ( all results with p 0,001 ) . With increasing birth-year sperm count as well as sperm concentration decreased . The causes for the observed decrease remain unresolved ."
],
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[
0,
978
]
]
}
] |
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325,
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] |
[] |
[] |
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{
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] |
Bundesgesundheitsblatt.90420499.eng.abstr
|
Bundesgesundheitsblatt.90420499.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-passage-0",
"type": "abstract",
"text": [
"This report focusses on the emergence and spread of S. aureus with special clinical and epidemiological significance . Results from typing MRSA originating from different clinical sources in all Germany reveal that there is a continuing interhospital dissemination of definite epidemic strains and also a spread of the mecA gene to clonal groups of S. aureus which have been until now sensitive . These newly emerging MRSA are still sensitive to a number of other antibiotics . This results in less broad resistance phenotypes of currently disseminated MRSA . Worth mentioning with regard to diagnostics are also three clinical cases of staphylococcal toxic shock syndrome caused by S. aureus possessing secC and not tst ."
],
"offsets": [
[
0,
722
]
]
}
] |
[
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"S. aureus"
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52,
61
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{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s2-t1",
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"text": [
"Germany"
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195,
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{
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"epidemic"
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277,
285
]
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"db_id": "C0014499"
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}
]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s2-t3",
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"text": [
"strains"
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[
286,
293
]
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{
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"db_id": "C0080194"
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]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s2-t4",
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"text": [
"gene"
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324,
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]
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{
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"db_id": "C0017337"
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{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s2-t5",
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"S. aureus"
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349,
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]
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]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"antibiotics"
],
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464,
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]
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},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"phenotypes"
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"db_name": "UMLS",
"db_id": "C0031437"
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{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"toxic"
],
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[
652,
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]
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"db_id": "C0600688"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"shock"
],
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[
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]
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]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t3",
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{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t4",
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"toxic shock"
],
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652,
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]
],
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{
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"db_id": "C0600327"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t5",
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"S. aureus"
],
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683,
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]
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},
{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s5-t6",
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"toxic shock syndrome"
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652,
672
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0600327"
}
]
}
] |
[] |
[] |
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{
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{
"id": "Bundesgesundheitsblatt.90420499.eng.abstr-s2-r9-t2.1-t5.1",
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"normalized": []
}
] |
Bundesgesundheitsblatt.90420507.eng.abstr
|
Bundesgesundheitsblatt.90420507.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Do hepatitis C virus ( HCV ) infected food handlers represent a risk for the consumer ? Epidemiological data on HCV transmission in our opinion do not provide a basis for excluding HCV positive individuals from working as food handlers in general . Such restrictions seem to be justified only if HCV infected employees might infect their colleagues while performing occupational activities that are associated with a high risk of contracting percutaneous injuries and overt bleeding ."
],
"offsets": [
[
0,
484
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t1",
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"hepatitis"
],
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[
3,
12
]
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]
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t2",
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"virus"
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15,
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]
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t3",
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"HCV"
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t4",
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"food"
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38,
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t5",
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"risk"
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64,
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]
},
{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t6",
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"hepatitis C"
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[
3,
14
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s1-t7",
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"hepatitis C virus"
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[
3,
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],
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"db_id": "C0220847"
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{
"db_name": "UMLS",
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]
},
{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s2-t1",
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"HCV"
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[
112,
115
]
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]
},
{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s2-t2",
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"transmission"
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[
116,
128
]
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s2-t3",
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"HCV"
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181,
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s2-t4",
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"food"
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"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s3-t1",
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"HCV"
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296,
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s3-t2",
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"text": [
"employees"
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[
309,
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]
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s3-t3",
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"risk"
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422,
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s3-t4",
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"injuries"
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{
"id": "Bundesgesundheitsblatt.90420507.eng.abstr-s3-t5",
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"risk of"
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]
}
] |
[] |
[] |
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] |
Bundesgesundheitsblatt.90420548.eng.abstr
|
Bundesgesundheitsblatt.90420548.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A report is given on the infection of pregnant women with Toxoplasma and on the laboratory diagnosis on mother , fetus and newborn . The next chapters deal with the consequences for the child and its chemotherapy . Prevention and problems of mother care are discussed in detail , as well as the infection as a notifiable one ."
],
"offsets": [
[
0,
326
]
]
}
] |
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t1",
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"infection"
],
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[
25,
34
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"db_id": "C0021311"
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t2",
"type": "umlsterm",
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"women"
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t3",
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"Toxoplasma"
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58,
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t4",
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"laboratory"
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t5",
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"diagnosis"
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"mother"
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"fetus"
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t8",
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"newborn"
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t9",
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"pregnant women"
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38,
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{
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"db_id": "C0033011"
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s1-t10",
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"laboratory diagnosis"
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{
"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s2-t1",
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"child"
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s2-t2",
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s3-t1",
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s3-t2",
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s3-t3",
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"id": "Bundesgesundheitsblatt.90420548.eng.abstr-s3-t4",
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}
] |
[] |
[] |
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Bundesgesundheitsblatt.90420553.eng.abstr
|
Bundesgesundheitsblatt.90420553.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The proportion of women among people with HIV infection and AIDS in Germany is considerably smaller than the proportion of men . The differential extent of the HIV epidemic in women in developed and developing countries is caused by certain social , cultural and economic conditions . During the course of the HIV epidemic in Germany the proportion of females among the infected persons has increased slowly , but steadily and has reached 20% by now . Also the transmission risks have changed . In the beginning of the epidemic the majority of women with HIV infection were IDU ( intravenous drug users ) , since the nineties the majority has been infected by heterosexual intercourse . Despite the increase of HIV infected females the number of perinatally infected children has been decreasing in the last five years . This is because a combination of antiretroviral prophylactic therapy with primary cesarean section as the mode of delivery has been established as the standard procedure in Germany . With this procedure the transmission risk from mother to children declined to below 2% . Because these measures can only be used , if the HIV status of the pregnant women is known , HIV antibody testing with adequate counselling should be offered to all pregnant women ."
],
"offsets": [
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0,
1274
]
]
}
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"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s8-r4-t1.1-t2.1",
"type": "isa",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s8-r5-t4.1-t5.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s8-r6-t5.1-t1.2",
"type": "uses",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s8-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s8-r7-t4.1-t1.1",
"type": "uses",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r1-t5.1-t8.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r2-t8.1-t4.1",
"type": "associated_with",
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"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r3-t8.1-t6.1",
"type": "performs",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r4-t8.1-t1.1",
"type": "associated_with",
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"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
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},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r5-t6.1-t5.1",
"type": "measures",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r6-t8.1-t5.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r7-t6.1-t8.1",
"type": "interacts_with",
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"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r8-t4.1-t8.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r9-t10.1-t6.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t10",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r10-t8.1-t3.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r11-t3.1-t10.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t3",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t10",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r12-t3.1-t6.1",
"type": "performs",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t3",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
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},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r13-t4.1-t5.1",
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"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
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{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r14-t10.1-t6.1",
"type": "performs",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t10",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r15-t5.1-t4.1",
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"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t4",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r16-t8.1-t6.1",
"type": "interacts_with",
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"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r17-t5.1-t1.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r18-t6.1-t1.1",
"type": "measures",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r19-t1.1-t8.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r20-t3.1-t8.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t3",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r21-t6.1-t8.1",
"type": "measures",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t8",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r22-t1.1-t5.1",
"type": "associated_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t1",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t5",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r23-t6.1-t10.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t6",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t10",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-r24-t10.1-t3.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t10",
"arg2_id": "Bundesgesundheitsblatt.90420553.eng.abstr-s9-t3",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420562.eng.abstr
|
Bundesgesundheitsblatt.90420562.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Children of mothers chronically infected with hepatitis-C-virus ( HCV ) during pregnancy and delivery were prospectively followed . 90 children born to 85 infected mothers were included in our study ; nine of the mothers were known to be co-infected with HIV-1. These 90 children were first tested within 60 days after birth and followed for at least three months . Three of the 90 children became infected perinatally with HCV as shown by persistence of antibodies after 2 years of life and a positive result in the RT-PCR . One of these 3 children has evidence of ongoing hepatitis as shown by slightly elevated alanine aminotransferase values , but is otherwise clinically well , likewise the other 2 infected children . 54 of the 87 uninfected children were followed until they lost maternal antibodies after an average of one year ."
],
"offsets": [
[
0,
837
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Children"
],
"offsets": [
[
0,
8
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"mothers"
],
"offsets": [
[
12,
19
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026591"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"HCV"
],
"offsets": [
[
66,
69
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220847"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"pregnancy"
],
"offsets": [
[
79,
88
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032961"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"delivery"
],
"offsets": [
[
93,
101
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011209"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"Children of"
],
"offsets": [
[
0,
11
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
135,
143
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"mothers"
],
"offsets": [
[
164,
171
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026591"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"mothers"
],
"offsets": [
[
213,
220
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026591"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
271,
279
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"birth"
],
"offsets": [
[
319,
324
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005615"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
382,
390
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"HCV"
],
"offsets": [
[
424,
427
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220847"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"antibodies"
],
"offsets": [
[
455,
465
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003241"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"life"
],
"offsets": [
[
483,
487
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0376558"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"RT-PCR"
],
"offsets": [
[
517,
523
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0599161"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
541,
549
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"hepatitis"
],
"offsets": [
[
574,
583
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019158"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"alanine"
],
"offsets": [
[
614,
621
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001898"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"aminotransferase"
],
"offsets": [
[
622,
638
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0002594"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"values"
],
"offsets": [
[
639,
645
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042295"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t6",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
713,
721
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t7",
"type": "umlsterm",
"text": [
"alanine aminotransferase"
],
"offsets": [
[
614,
638
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001899"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"children"
],
"offsets": [
[
748,
756
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"antibodies"
],
"offsets": [
[
796,
806
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003241"
}
]
}
] |
[] |
[] |
[
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r1-t2.1-t6.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t2",
"arg2_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t6",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r2-t1.1-t2.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t1",
"arg2_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r3-t5.1-t3.1",
"type": "affects",
"arg1_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t5",
"arg2_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r4-t6.1-t2.1",
"type": "interacts_with",
"arg1_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t6",
"arg2_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r5-t3.1-t1.1",
"type": "produces",
"arg1_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s4-t3",
"arg2_id": "Bundesgesundheitsblatt.90420562.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420562.eng.abstr-s1-r6-t1.1-t5.1",
"type": "performs",
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Bundesgesundheitsblatt.90420569.eng.abstr
|
Bundesgesundheitsblatt.90420569.eng.abstr
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[
{
"id": "Bundesgesundheitsblatt.90420569.eng.abstr-passage-0",
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[] |
[] |
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Bundesgesundheitsblatt.90420631.eng.abstr
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Bundesgesundheitsblatt.90420631.eng.abstr
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[
{
"id": "Bundesgesundheitsblatt.90420631.eng.abstr-passage-0",
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"K+ Channels and Cardiotoxicity of Drugs : Implications for Drug Toxicity Assessment - The time required for repolarization of the ventricles can be measured as the QT interval of the ECG and is determined primarily by activation of the delayed rectifier K+ current ( IK ) , which consists of a rapid component ( IKr ) and a slow component ( IKs ) . Drugs that block cardiac IKr prolong the cardiac action potential ( AP ) . Prolonged repolarization is detected as a longer QT interval on the ECG . During prolonged APs , increased inward currents induce early afterdepolarizations , which increase the risk of Torsades de pointes ( TdP ) cardiac arrhythmias . TdP arrhythmia is characterized by an apparent twisting of the electrical axis around the isoelectric line . It has a rate of 150 to 250 beats/min and it can occasionally degenerate into ventricular fibrillation that may be fatal . The incidence of drug-induced TdP arrhythmias is highest among class IA and class III antiarrhythmic agents . However , under certain clinical conditions , also several non-cardiovascular medicinal products induce QT interval prolongations in the ECG or TdP arrhythmias . Since all drugs known to cause TdP block IKr , an early evaluation of possible effects on APs of cardiac myocytes expressing IKr channels during the developmental phases of novel drugs seems to be recommended . If in-vitro electrophysiological studies show the new active substance to induce AP prolongation and/or K+ channel blockade in appropriate models and at relevant concentrations , either further development of the new active substance may not be justified or the risk factors predisposing to TdP arrhythmias should be taken into account in further clinical studies ."
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Bundesgesundheitsblatt.90420643.eng.abstr
|
Bundesgesundheitsblatt.90420643.eng.abstr
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[
{
"id": "Bundesgesundheitsblatt.90420643.eng.abstr-passage-0",
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"The microscopic examination of Giemsa-stained blood films for the diagnosis of malaria is a highly sensitive technique . However , the expertise required is a major disadvantage . Recently , methods not dependent on microscopy have become commercially available . The use of an antigen-capture assay for the detection of histidine-rich protein 2 , an antigen specific for Plasmodium falciparum , forms the basis of the ParaSight-F ( Becton Dickinson ) and the ICT Malaria Pf test ( ICT Diagnostics ) . Parasite lactate dehydrogenase is the basis of another immunographic dipstick assay developed by Flow Inc. These currently available assays have been evaluated in a number of trials giving sensitivities and specificities of 90-100% . A decreased sensitivity is found in cases with low parasitemia . However , false-negative results have also been reported in patients with high parasite densities ."
],
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[] |
[] |
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Bundesgesundheitsblatt.90420650.eng.abstr
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Bundesgesundheitsblatt.90420650.eng.abstr
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[] |
[] |
Bundesgesundheitsblatt.90420657.eng.abstr
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Bundesgesundheitsblatt.90420657.eng.abstr
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"In 1996 , several employees of the French governmental organization for Blood Collection and Transfusions ( CNTS ) have been condemned by ordinary courts . They were found guilty in the affair on HIV-infected blood transfusions . Over 3800 persons , mostly hemophiliacs , have been infected in France and suffer from HIV disease . Many of them died already . The public in France urgently demanded the condemnation of the persons who were politically responsible for the time delay that postponed the introduction of HIV-tests for blood donations in France . Such a test was available from the american company ABBOTT in the early 1985 , but the french authorities preferred to wait for the HIV-Test from Pasteur-Diagnostics . A special court , the \" Court de Justice de la République \" , authorized to judge on members of the governement , has been created by the French Parliament on Nov. 23 , 1993. Six years later , the three politicians , the former Prime Minister Laurent Fabius , the minister for Social Affairs , Mme Georgina Dufoix , and her undersecretary of state for health , Mr. Edmond Hervé , have been accused of involuntary homicide . March , 9 , 1999 , after five weeks of deliberations and statements , the CJR rendered his sentence : The former Prime Minister Laurent Fabius and the Minister G. Dufoix were discharged , but the secretary of state for health , Edmond Hervé , has been declared guilty . However , also Mr. Hervé could leave the court room as a free person , because the President of the Court , Mr. Christian Le Gunehec , didn ' t want to pronounce a judgement against him , as Mr. Hervé had to suffer from almost 15 years of public critics and attacks before he was found guilty . The hemophiliacs and other AIDS-patients as well as their families protested loudly against this judgement . They plan to file charges against the three ministers through a common court to hold them responsible ."
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[] |
[] |
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] |
Bundesgesundheitsblatt.90420683.eng.abstr
|
Bundesgesundheitsblatt.90420683.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420683.eng.abstr-passage-0",
"type": "abstract",
"text": [
"From a global viewpoint , tuberculosis is one of the most important infectious diseases of our time . The situation in Germany , as in most comparable industrialized nations , is stable . The declining trend of previous years continued in 1997 , when 11,163 people developed active tuberculosis - an incidence of 13.6/100,000. However , the tuberculosis problem cannot be restricted to one country , and Germany is particularly affected by trends in Eastern Europe and in the former Soviet countries . These countries experienced a marked increase of tuberculosis cases and resistant strains during recent years , a tendency which can only be countered by fast , well-aimed and efficient action in the affected areas . The industrialized nations in particular should consider financial and logistic contributions as their duty . Crucial for control of the tuberculosis situation within each country are registration and close observation of epidemiological trends , identification of high-risk groups , and continuation of established tuberculosis control measures ."
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Bundesgesundheitsblatt.90420706.eng.abstr
|
Bundesgesundheitsblatt.90420706.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420706.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Tuberculosis is , on a global level , still one of the most important infectious diseases . Effective control of tuberculosis could probably be achieved by a combination of chemotherapy and vaccination . Although a vaccine ( BCG ) is available , it cannot prevent the development of tuberculosis of the lungs in adults as the most frequent disease manif- estation . The development of a new vaccine against tuberculosis therefore remains a primary goal . Because the immune defense against M. tuberculosis depends on different T-cell subpopulations , the optimal combination has to be stimulated to achieve protection . Because one third of the world population is already infected with M. tubercolosis , possibly two vaccines are needed : one therapeutic vaccine to fight an already estab- lished infection and a preventive vaccine . Currently different vaccine candidates are under development . It is still to early to predict , which may be successful ."
],
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0,
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] |
[] |
[] |
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Bundesgesundheitsblatt.90420713.eng.abstr
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Bundesgesundheitsblatt.90420713.eng.abstr
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}
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Bundesgesundheitsblatt.90420717.eng.abstr
|
Bundesgesundheitsblatt.90420717.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420717.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The methodology of transformation assays in in vitro carcinogenesis has been continuously improved to make them routinely applicable . In most of the recently employed transformation assays colony counting was performed under a stereo microscope . We have investigated the application of a computerized image analysing system to determine transformed colonies after in vitro cultivation of epithelial canine kidney cells . Special intention was imposed on the calibration of the system . First results show that determination of number and surface of transformed colonies in soft agar were rapidly available . In addition a high level of reproducibility and a thereby enhanced reliability could be achieved . The implementation of such a computerized image analysis in routine performance of transformation assays would enhance its robustness and applicability and minimize the bias due to evaluation under the stereo microscope to an important extent . It may also be used for similar purpos ( e.g. cytogenetic tests ) ."
],
"offsets": [
[
0,
1021
]
]
}
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401,
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"id": "Bundesgesundheitsblatt.90420717.eng.abstr-s3-t2",
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"id": "Bundesgesundheitsblatt.90420717.eng.abstr-s4-t2",
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] |
[] |
[] |
[
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{
"id": "Bundesgesundheitsblatt.90420717.eng.abstr-s3-r3-t2.1-t1.1",
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{
"id": "Bundesgesundheitsblatt.90420717.eng.abstr-s3-r4-t3.1-t2.1",
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"id": "Bundesgesundheitsblatt.90420717.eng.abstr-s8-r1-t2.1-t1.1",
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Bundesgesundheitsblatt.90420722.eng.abstr
|
Bundesgesundheitsblatt.90420722.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In various laboratories the microbiological quality from water of 124 showers for eyes was investigated . Only 17.8% of the watersamples showed bacterial counts 100 CFU/ml . Over 104 CFU/ml were found in 39,5% . The optical assessment of the water revealed that only 49,2% watersamples were rated as \" clear \" , whereas 20,2% showed high turbidity and intense precipitates . This study shows that such eye showers are problematic from the infectiological standpoint . Therefore it is proposed to use water from the water tap instead of showers for eyes ."
],
"offsets": [
[
0,
554
]
]
}
] |
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11,
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s1-t2",
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]
},
{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s1-t4",
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"text": [
"eyes"
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[
82,
86
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"db_name": "UMLS",
"db_id": "C0015392"
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{
"db_name": "UMLS",
"db_id": "C0023924"
}
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s2-t1",
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124,
136
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124,
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s2-t3",
"type": "umlsterm",
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"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s2-t4",
"type": "umlsterm",
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"bacterial counts"
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144,
160
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{
"db_name": "UMLS",
"db_id": "C0004618"
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s4-t1",
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"assessment"
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s4-t2",
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{
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{
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273,
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"eye"
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402,
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"db_name": "UMLS",
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{
"id": "Bundesgesundheitsblatt.90420722.eng.abstr-s6-t1",
"type": "umlsterm",
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Bundesgesundheitsblatt.90420758.eng.abstr
|
Bundesgesundheitsblatt.90420758.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420758.eng.abstr-passage-0",
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"Despite wide-spread immunisation programs epidemic influenza continues to cause ten thousands of deaths worldwide , every year , especially in the high risk groups of elderly or immunocompromised persons . At present , amantadine and rimantadine are the only approved agents available for prophylactic and therapeutic use , yet , the deployment of these substances is problematic : neither of the two drugs is effective against influenza B , their use is accompanied by rapid development of viral resistance , and they show many adverse effects . In contrast , zanamivir and GS4071/GS4104 are rationally developed influenza-specific neuraminidase inhibitors , proving prophylactic and therapeutic efficacy against influenza A and B , as well in vitro as in animal models , and in experimental human studies . Zanamivir and GS4071/GS4104 are well tolerated without adverse reactions after topic and oral administration , respectively . Resistant viral strains have been found in cell culture in the presence of both drugs , but the frequency of resistance emergence during clinical use is unclear . To date , the biggest recognizable disadvantage of neuraminidase inhibitors and Amantadin/Rimantadin alike is that they need to be given within 30-48 h after onset of symptoms , but seeking medical attention at this stage of infection does not seem to be realistic in medical practice . As neuraminidase inhibitors up to now could mainly be assessed by experimental data , specifically performed clinical trials will have to prove the positive influence of these drugs on the morbidity , course of infection , and mortality of high risk persons when administered for prophylaxis as well as for therapy ."
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Bundesgesundheitsblatt.90420763.eng.abstr
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"id": "Bundesgesundheitsblatt.90420763.eng.abstr-s4-r22-t2.2-t1.1",
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"id": "Bundesgesundheitsblatt.90420763.eng.abstr-s4-r23-t2.2-t1.1",
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"normalized": []
}
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Bundesgesundheitsblatt.90420769.eng.abstr
|
Bundesgesundheitsblatt.90420769.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420769.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The occurrence of a new influenza virus subtype in 1997 in Hongkong caused only minor outbreaks due to the swift and determined actions of the institutions involved . However , this incident again made it clear that an influenza pandemic is still a pending threat . As a result the WHO presented a pandemic preparedness plan which is to facilitate the global measures taken to fight an imminent or ongoing pandemic . Strong efforts of influenza surveillance and the coordination of worldwide measures are essential to this plan . Furthermore the WHO suggested the developement and introduction of similar national preparedness plans ."
],
"offsets": [
[
0,
634
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420769.eng.abstr-s1-t1",
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"occurrence"
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14
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{
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{
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"outbreaks"
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}
]
}
] |
[] |
[] |
[
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},
{
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{
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{
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{
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{
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},
{
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{
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{
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},
{
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{
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},
{
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},
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},
{
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},
{
"id": "Bundesgesundheitsblatt.90420769.eng.abstr-s4-r10-t3.1-t6.1",
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},
{
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},
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{
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{
"id": "Bundesgesundheitsblatt.90420769.eng.abstr-s4-r14-t2.2-t1.1",
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},
{
"id": "Bundesgesundheitsblatt.90420769.eng.abstr-s4-r15-t5.1-t1.1",
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"arg2_id": "Bundesgesundheitsblatt.90420769.eng.abstr-s4-t4",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420776.eng.abstr
|
Bundesgesundheitsblatt.90420776.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Herpes simplex virus type 1 ( HSV-1) and type 2 ( HSV-2) are the most frequent infections cause of genital ulcerations . Although genital infections by HSV-1 are increasing HSV-2 is dominant in recurrent infections . This study was conducted on a panel of sera collected anonymously in 1996 and 1997 from blood donors ( 1979 samples ) and hospital patients ( 3079 samples ) without risk factors for herpesvirus infections such as STD , other infectious diseases and immunosuppression . Serum samples were tested with ELISAs using monoclonal antibody-selected native gG1 and gG2 as antigens and an immunoblot using type-specific recombinant glycoproteins . Equivocal results were confirmed with an in-house Western blot ."
],
"offsets": [
[
0,
720
]
]
}
] |
[
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Herpes"
],
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[
0,
6
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019369"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"simplex"
],
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[
7,
14
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0142328"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"virus"
],
"offsets": [
[
15,
20
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042776"
},
{
"db_name": "UMLS",
"db_id": "C0521026"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"infections"
],
"offsets": [
[
79,
89
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"cause"
],
"offsets": [
[
90,
95
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015127"
}
]
},
{
"id": "Bundesgesundheitsblatt.90420776.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"ulcerations"
],
"offsets": [
[
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Bundesgesundheitsblatt.90420827.eng.abstr
|
Bundesgesundheitsblatt.90420827.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420827.eng.abstr-passage-0",
"type": "abstract",
"text": [
"ICD-10 is to be implemented for morbidity coding in Germany soon . The electronic versions of ICD-10 are introduced . For everyday work with the classification and for epidemiological research further tools are provided by DIMDI : ICD-10 meta files , ICD conversion tables , ICD-10 thesaurus of diagnostic terms . All files are available free of charge via the INTERNET ."
],
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[
0,
371
]
]
}
] |
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{
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]
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"Germany"
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] |
[] |
[] |
[
{
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"type": "measurement_of",
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{
"id": "Bundesgesundheitsblatt.90420827.eng.abstr-s3-r3-t2.2-t4.1",
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"arg2_id": "Bundesgesundheitsblatt.90420827.eng.abstr-s3-t4",
"normalized": []
}
] |
Bundesgesundheitsblatt.90420834.eng.abstr
|
Bundesgesundheitsblatt.90420834.eng.abstr
|
[
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The variability of genes coding for xenobiotic metabolizing enzymes is an important reason for individual variations in susceptibilities towards chemical toxicants . In environmental and occupational medicine , polymorphisms of different isoforms of cytochrome P450, of N-acetyl-transferase ( NAT2) and of glutathione transferase ( GSTT1, GSTM1) are now of importance . In particular , the cytochrome P450 isoenzyme CYP2E1 is a key enzyme of the oxidative metabolism of highly relevant industrial chemicals as it metabolizes alkenes as well as aromatic and halogenated hydrocarbons . The influence of N-acetyltransferase 2 ( NAT2) on the carcinogenic effect of aromatic amines upon the urothelium has been well established ; the N-oxidation of aromatic amines leading to toxic and carcinogenic intermediates is higher in \" slow \" compared to \" rapid \" acetylators . In general , it is now evident that polymorphisms of xenobiotic metabolizing enzymes may have a decisive role in modulating the effects of toxicants on humans . Further progress in this field is to be expected , and calls for intensive discussion of both the preventiv and sociopolitical aspects ."
],
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0,
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]
}
] |
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"text": [
"enzymes"
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]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s1-t4",
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"variations"
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106,
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]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s1-t5",
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s2-t1",
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]
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"db_id": "C0597298"
}
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}
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},
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s2-t5",
"type": "umlsterm",
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"glutathione"
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}
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s2-t6",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s2-t7",
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],
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}
]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s2-t8",
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],
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]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t1",
"type": "umlsterm",
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"cytochrome"
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},
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t2",
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]
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]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t6",
"type": "umlsterm",
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},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t7",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t8",
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},
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t9",
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},
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},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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]
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t5",
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],
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]
}
] |
[] |
[] |
[
{
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"type": "issue_in",
"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
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},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s1-r3-t1.1-t2.1",
"type": "produces",
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{
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"type": "interacts_with",
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{
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s1-r7-t5.1-t3.2",
"type": "result_of",
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},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s1-r8-t2.1-t1.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-r12-t5.2-t4.2",
"type": "issue_in",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t4",
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"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-r14-t1.1-t2.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-r15-t1.1-t9.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s3-t9",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s4-r1-t2.1-t3.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s4-r2-t3.1-t4.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s4-r3-t4.1-t2.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s4-r4-t2.1-t1.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s4-r5-t2.1-t4.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r1-t5.1-t3.2",
"type": "exhibits",
"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t5",
"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r2-t2.1-t3.2",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r3-t3.1-t2.1",
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"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r4-t2.1-t3.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r5-t1.1-t3.1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r6-t1.1-t3.2",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r7-t2.1-t1.1",
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"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r8-t3.1-t1.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t1",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r9-t1.1-t2.1",
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"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t2",
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{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r11-t5.1-t3.2",
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"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t5",
"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-r12-t1.1-t5.1",
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"arg1_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t1",
"arg2_id": "Bundesgesundheitsblatt.90420834.eng.abstr-s5-t5",
"normalized": []
}
] |
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