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DerChirurg.70680477.eng.abstr
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DerChirurg.70680477.eng.abstr
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"This article reviews the molecular basis of cell adhesion and its possible implications in surgery . Adhesion of circulating cells to endothelial cells is mediated by a variety of celladhesion molecules . The first steps in the celladhesion cascade ( rolling , tethering ) are regulated by selectins ( P , E , L selectin ) . Stable adhesion and transmural migration predominantly involve integrins ( LFA-1, etc. ) and members of the immunoglobulin supergene family ( ICAM-1, etc. ) . The mechanisms of leucocyte-endothelial interaction are markedly similar in various organs under both physiological and pathophysiological conditions . However , it is likely that cell trafficing to specific tissues/organs ( e.g. , homing ) is regulated by additional organ-specific , topical adhesion molecules ( e . g . , MAdCAM-1). In surgery , cell adhesion molecules are involved in organ-transplantation pathology ( ischemia/reperfusion injury , rejection ) , inflammation ( e.g. , chronic inflammatory bowel diseases ) , tumor metastasis . Animal experiments with anti-adhesive substances show that blocking the leukocyte-endothelial interaction reduces the cellular inflammatory infiltrate and organ rejection . The transfer of experimental data into clinical practice requires further understanding of the regulators of cell adhesion ( cytokines , chemoattractant substances , etc. ) and the specificity of the process . Current experimental data suggest that early intervention in cell-adhesion mechanisms may offer innovative therapeutic strategies ."
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[] |
[] |
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] |
DerChirurg.70680488.eng.abstr
|
DerChirurg.70680488.eng.abstr
|
[
{
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"type": "abstract",
"text": [
"The aim of any abdominal wall reconstruction is maximal functional stability and adequate soft tissue coverage . The anatomy , elevation and clinical application of the myofascial tensor fasciae latae transposition flap and of the microvascular musculocutaneous latissimus dorsi free flap are presented . Repairing extensive fascial defects and recurrent hernias with the tensor fasciae latae transposition flap provides strong , dynamic , and functional reconstruction of fascial continuity to prevent a further recurrence . Adequate functional and aesthetic repair of a full-thickness abdominal wall defect can be optimally managed by the innervated microsurgical latissimus dorsi free flap ."
],
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[
0,
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]
}
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"id": "DerChirurg.70680488.eng.abstr-s4-t4",
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] |
[] |
[] |
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] |
DerChirurg.70680493.eng.abstr
|
DerChirurg.70680493.eng.abstr
|
[
{
"id": "DerChirurg.70680493.eng.abstr-passage-0",
"type": "abstract",
"text": [
"During total extraperitoneal dissection of inguinal hernias , an artificial preperitoneal cavity is created in the supravesical space by using a balloon dissector . During the operative procedure in vivo and while examining cadavers specially fixated according to the method developed by Thiel in 1992 , we investigated the position relative to the balloon the transversalis fascia could be found in and what happened to it during inflation of the balloon . In all cases , the fascia medial to the inferior epigastric arteries was adjacent to the peritoneum and lateral to the abdominal wall . We observed systematic tearing of the fascia along the lateral umbilical plica ( inferior epigastric artery ) . These results suggested that the transversalis fascia could be used only laterally for reinforcement of the dorsal wall of the inguinal canal and/or the support of a mesh used to cover the inguinal floor ."
],
"offsets": [
[
0,
911
]
]
}
] |
[
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"id": "DerChirurg.70680493.eng.abstr-s1-t2",
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{
"id": "DerChirurg.70680493.eng.abstr-s1-t3",
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{
"id": "DerChirurg.70680493.eng.abstr-s2-t6",
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"inflation"
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"id": "DerChirurg.70680493.eng.abstr-s2-t7",
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{
"id": "DerChirurg.70680493.eng.abstr-s3-t1",
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{
"id": "DerChirurg.70680493.eng.abstr-s3-t2",
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{
"id": "DerChirurg.70680493.eng.abstr-s3-t3",
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},
{
"id": "DerChirurg.70680493.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"epigastric arteries"
],
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"db_id": "C0282640"
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{
"id": "DerChirurg.70680493.eng.abstr-s3-t5",
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},
{
"id": "DerChirurg.70680493.eng.abstr-s4-t1",
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{
"id": "DerChirurg.70680493.eng.abstr-s4-t2",
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{
"id": "DerChirurg.70680493.eng.abstr-s4-t3",
"type": "umlsterm",
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}
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},
{
"id": "DerChirurg.70680493.eng.abstr-s4-t4",
"type": "umlsterm",
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DerChirurg.70680496.eng.abstr
|
DerChirurg.70680496.eng.abstr
|
[
{
"id": "DerChirurg.70680496.eng.abstr-passage-0",
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"In an experimental study , the biomechanical qualities of the combined Kirschner wire osteosynthesis ( KWO ) in the unstable Colles ' fracture were analyzed . This type of pin fixation is our preferred osteosynthesis in the treatment of unstable Colles ' fracture because it allows immediate functional therapy . It represents a modification of Kapandji's dynamic KWO , compensating for the insufficient volar stability by means of the conventional static KWO . Clinical experience according to the anatomical and functional results , was very encouraging suggesting that a clinical concept based on the biomechanical principles of combined KWO and its single components should be constituted . Simulation of the unstable Colles ' fracture was realized by dorsal wedge osteotomy of the distal end of the radius using cadaveric material . This fracture model was subsequently pinned using the different KWO types and tested by a standardized vector energy testing device regarding its stability in the four main loading directions . The combined KWO unifies the advantage of volar stability of the conventional KWO with the high dorsal stability of dynamic KWO . The main functional principle of dynamic KWO with regard to its axial stability consists in the repositioning of the dorsal bone fragmentation zone and hence the reconstitution of cortical load transmission . Besides its good stabilization , dynamic KWO also leads to optimal alignment of the distal metaphyseal fragment . Furthermore , the experiments yielded important information about technical aspects of the surgical procedure , which helps us to avoid anatomical and functional deficiencies . Based on these experimental findings , the surgical technique of combined KWO was standardized ."
],
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0,
1758
]
]
}
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] |
[] |
[] |
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DerChirurg.70680513.eng.abstr
|
DerChirurg.70680513.eng.abstr
|
[
{
"id": "DerChirurg.70680513.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A potential role of homozygous or heterozygous alpha-1-antitrypsin deficiency alleles Pi*Z or Pi*S in the pathogenesis of aortic aneurysms has been debated in recently published papers . Therefore , we have determined the alpha-1-antitrypsin phenotype in 103 patients with aortic aneurysms using isoelectric focusing . The vast majority of patients ( 92.2 % ) had one or more of the established risk factors : hypertension ( 65.0 % ) , lipometabolic dysfunction ( 34.9 % ) , smoking ( 65.0 % ) , hyperuricemia ( 16.5 % ) or diabetes mellitus ( 8.7 % ) . In our patients , the deficiency alleles Pi*Z and Pi*S were more frequent than in the general population of our region , but these differences did not reach statistical significance ( PiMS 6.7 versus 3.4 % , PiMZ 3.8 versus 2.5 % , PiSS 0,9 versus 0.2 % ) . Furthermore , the patients with heterozygous or homozygous antitrypsin deficiency had similar patterns of risk factors to those of the patients with normal phenotypes . In one patient we found a heterozygous PiMZ antitrypsin deficiency associated with Marfan's syndrome . These data do not support the results of recently published studies of fewer cases that suggest a higher prevalence of antitrypsin deficiency alleles in patients with aortic aneurysms . A heterozygous alpha-1-antitrypsin deficiency as a cause or predisposing factor for the development of aortic aneurysms appears to be of little or no importance ."
],
"offsets": [
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1432
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]
}
] |
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"id": "DerChirurg.70680513.eng.abstr-s1-t3",
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{
"id": "DerChirurg.70680513.eng.abstr-s2-t2",
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{
"id": "DerChirurg.70680513.eng.abstr-s2-t3",
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"id": "DerChirurg.70680513.eng.abstr-s3-t3",
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"id": "DerChirurg.70680513.eng.abstr-s3-t5",
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{
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{
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] |
DerChirurg.70680517.eng.abstr
|
DerChirurg.70680517.eng.abstr
|
[
{
"id": "DerChirurg.70680517.eng.abstr-passage-0",
"type": "abstract",
"text": [
"According to sonographic criteria , 55 patients underwent surgical treatment with mobilisation in a lower leg plaster or conservative treatment with early mobilisation in heel pad ( 3 cm ) shoes when an acute Achilles tendon rupture ( ATR ) was diagnosed . The follow-up period in 51 patients was 2.4 years ( operated group = 28 patients , conservative group = 23 patients ) with clinical examination and testing of isokinetic muscle strength in knee joint flexion . After surgical treatment , minor wound infections occurred in 10.6 % . Reruptures occurred in 13 % of the conservative group . Following conservative treatment , the rate of stress-related achillodynia was significantly higher ( P = 0.019 ) . In the operated group mean isokinetic muscle strength was 13.7 % lower than in the uninvolved leg and decreased significantly with non-operative treatment to 75.3 % ( P = 0.012 ) . We recommend surgical treatment of acute ATR . The indications for conservative treatment depend on the extent of the rupture ( measured by ultrasound in the equinus position ) , the desired level of daily activity and the patient's degree of compliance ."
],
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[
0,
1146
]
]
}
] |
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DerChirurg.70680525.eng.abstr
|
DerChirurg.70680525.eng.abstr
|
[
{
"id": "DerChirurg.70680525.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The endoscopic release of the carpal ligament gives the opportunity to treat the carpal tunnel syndrome in a comfortable and minimal invasive way . Between 1 October 1994 and 7 May 1995 , 46 patients who underwent endoscopic surgery on 55 hands were documented in a prospective study . The following results were taken from a questionnaire . There were not any complaints , or the complaints were so much diminished that complete division of the carpal ligament could be viewed as accomplished in 51 of 55 cases . There were continuing complaints in four cases , and after an additional check two patients were operated on again . The advantage of the endoscopic method is the inconspicuous scar and the reduced postoperative disablement . No complications have occurred ."
],
"offsets": [
[
0,
772
]
]
}
] |
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22
]
],
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}
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{
"id": "DerChirurg.70680525.eng.abstr-s1-t2",
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"carpal"
],
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36
]
],
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}
]
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{
"id": "DerChirurg.70680525.eng.abstr-s1-t3",
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],
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]
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{
"id": "DerChirurg.70680525.eng.abstr-s1-t4",
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],
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103
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191,
199
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"db_id": "C0030705"
}
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},
{
"id": "DerChirurg.70680525.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"surgery"
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[
225,
232
]
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"db_id": "C0038894"
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},
{
"id": "DerChirurg.70680525.eng.abstr-s2-t5",
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"text": [
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{
"id": "DerChirurg.70680525.eng.abstr-s2-t6",
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DerChirurg.70680531.eng.abstr
|
DerChirurg.70680531.eng.abstr
|
[
{
"id": "DerChirurg.70680531.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Translaryngeal tracheostomy is a new type of minimally invasive technique for bedside tracheostomy in intensive care patients . After percutaneous puncture of the trachea below the first tracheal ring , a conic tracheal cannula is fixed to an orally forwarded guide wire . The cannula is then pulled through in orthograde fashion set up , rotated and pushed forward caudally . Among the first 25 translaryngeal tracheostomies in 24 patients , only two complications appeared : one misplacement of the cannula and one infection of the stoma . During a median apnoea time of about 80 s an average PaCO2 increase of 8.0 +/- 6.8 mm Hg was documented ; hypoxias could not be seen . Translaryngeal tracheostomy seems to be an appropriate alternative to established tracheostomy methods ."
],
"offsets": [
[
0,
781
]
]
}
] |
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] |
[] |
[] |
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] |
DerChirurg.70680536.eng.abstr
|
DerChirurg.70680536.eng.abstr
|
[
{
"id": "DerChirurg.70680536.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report the case of a 64-year-old female with an intrahepatic aneurysm of the right hepatic artery . Initially uncharacteristic upper abdominal symptoms were followed by repeated upper gastrointestinal bleeding and , eventually , hemorrhagic shock . Finding the cause of severe hematemesis was challenging due to a previous Billroth-II gastric resection . Delayed diagnosis of hemobilia necessitated coeliacography , whereby an intrahepatic aneurysm of the right hepatic artery was found and , during the same session , superselective embolization was achieved . If the cause of upper abdominal complaints remains unknown after routine diagnostic measures and the origin of bleeding in the upper gastrointestinal tract cannot be identified , aneurysms of abdominal arteries should be considered . Hemobilia of unknown etiology should always be an indication for coeliacography . The superselective angiographic embolization of intrahepatic aneurysms is a promising form of treatment with low risk ."
],
"offsets": [
[
0,
1000
]
]
}
] |
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{
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}
] |
[] |
[] |
[
{
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"type": "associated_with",
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DerChirurg.70680540.eng.abstr
|
DerChirurg.70680540.eng.abstr
|
[
{
"id": "DerChirurg.70680540.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Gastric involvement of Hodgkin's disease is very rare and preoperative diagnosis is difficult . We report the case of a 50-year-old woman , who had an ulcerating tumor of the antrum , which was revealed as carcinoma by endoscopic biopsy . A gastrectomy with D2-lymph node dissection was performed . In the pathological specimen Hodgkin's disease was diagnosed because of microscopic detection of typical binucleated Reed-Sternberg cells . Although the patient refused additive chemotherapy , she is still disease-free after 12 months of follow-up ."
],
"offsets": [
[
0,
548
]
]
}
] |
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DerChirurg.70680543.eng.abstr
|
DerChirurg.70680543.eng.abstr
|
[
{
"id": "DerChirurg.70680543.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The therapy for spontaneous or artificial perforation of the esophagus remains a controversial matter . The following case report deals with the medical history of an artificial esophageal perforation after operative treatment of cervical disc disease . A 68-year-old male patient underwent a C4/C5 and C5/C6 discectomy with interbody fusion of C7-T1 vertebral body , according to Smith-Robinson . During this operation , a 3-cm-long lesion was made in the posterior wall of the esophagus , which was treated 24 h later with a primary suture . The clinical follow-up was complicated by mediastinitis with subsequent multiorgan failure . After recovery from this critical condition the patient complained of severe dysphagia , which was related to a persistent lesion in the posterior esophageal wall with endoscopically demonstrated dislocation of a screw . After removal of the screw , the lesion was covered by means of sternocleidomastoid myoplasty . Moderate postoperative dysphagia was successfully treated by bougienage ."
],
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[
0,
1027
]
]
}
] |
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[] |
[] |
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}
] |
DerChirurg.70680551.eng.abstr
|
DerChirurg.70680551.eng.abstr
|
[
{
"id": "DerChirurg.70680551.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Trauma , operative interventions , infection and other disturbances of homeostasis lead to a uniform reaction of the body , namely release and activation of hormones and cytokines . Profound alterations of substrate flow result , with mobilization of energy stores and degradation of structural and functional proteins of vital organs like the gut mucosa . Due to these reactions the energy demands of the organs are met and energy-consuming synthesis of substrates is indicated . Clinically , hypermetabolism , hyperglycemia , lipolysis and increased urea production with negative nitrogen balance can be observed . The metabolic reactivity is reached by an increased substrate cycling . To avoid negative consequences such as organ dysfunction , a rational situation-adapted substrate supply is warranted as well as reduction of catabolic stimuli and stimulation of anabolic factors . The metabolic care of the surgical patient is still a basic and important task ."
],
"offsets": [
[
0,
967
]
]
}
] |
[
{
"id": "DerChirurg.70680551.eng.abstr-s1-t1",
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"text": [
"Trauma"
],
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[
0,
6
]
],
"normalized": [
{
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"db_id": "C0021501"
},
{
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"db_id": "C0043251"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"infection"
],
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[
35,
44
]
],
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{
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"db_id": "C0021311"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"homeostasis"
],
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[
71,
82
]
],
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{
"db_name": "UMLS",
"db_id": "C0019868"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"lead"
],
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[
83,
87
]
],
"normalized": [
{
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"db_id": "C0023175"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"release"
],
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[
131,
138
]
],
"normalized": [
{
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"db_id": "C0541720"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"hormones"
],
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[
157,
165
]
],
"normalized": [
{
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"db_id": "C0019932"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"cytokines"
],
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[
170,
179
]
],
"normalized": [
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"db_id": "C0079189"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"mobilization"
],
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[
235,
247
]
],
"normalized": [
{
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"db_id": "C0300926"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"degradation"
],
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[
269,
280
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243125"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"proteins"
],
"offsets": [
[
310,
318
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0033684"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
348,
354
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"hyperglycemia"
],
"offsets": [
[
512,
525
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020456"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"lipolysis"
],
"offsets": [
[
528,
537
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023796"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"urea"
],
"offsets": [
[
552,
556
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041942"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"production"
],
"offsets": [
[
557,
567
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0033268"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"nitrogen"
],
"offsets": [
[
582,
590
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0028158"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s4-t6",
"type": "umlsterm",
"text": [
"balance"
],
"offsets": [
[
591,
598
]
],
"normalized": [
{
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"db_id": "C0014653"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"substrate cycling"
],
"offsets": [
[
669,
686
]
],
"normalized": [
{
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"db_id": "C0038591"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"dysfunction"
],
"offsets": [
[
734,
745
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0031847"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"supply"
],
"offsets": [
[
787,
793
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0243163"
},
{
"db_name": "UMLS",
"db_id": "C0038848"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"care"
],
"offsets": [
[
901,
905
]
],
"normalized": [
{
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"db_id": "C0150499"
}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"surgical"
],
"offsets": [
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913,
921
]
],
"normalized": [
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}
]
},
{
"id": "DerChirurg.70680551.eng.abstr-s7-t3",
"type": "umlsterm",
"text": [
"patient"
],
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[
922,
929
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
}
] |
[] |
[] |
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"type": "produces",
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{
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"id": "DerChirurg.70680551.eng.abstr-s1-r6-t7.1-t1.1",
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},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r7-t2.1-t1.1",
"type": "associated_with",
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{
"id": "DerChirurg.70680551.eng.abstr-s1-r8-t7.1-t2.1",
"type": "indicates",
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},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r9-t4.1-t3.1",
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},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r10-t3.1-t5.1",
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"normalized": []
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r11-t5.1-t3.1",
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"arg2_id": "DerChirurg.70680551.eng.abstr-s7-t3",
"normalized": []
},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r12-t1.1-t3.1",
"type": "evaluation_of",
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{
"id": "DerChirurg.70680551.eng.abstr-s1-r13-t5.1-t4.1",
"type": "interacts_with",
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},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r14-t7.1-t3.1",
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},
{
"id": "DerChirurg.70680551.eng.abstr-s1-r15-t4.1-t2.1",
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"arg1_id": "DerChirurg.70680551.eng.abstr-s4-t4",
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"normalized": []
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DerChirurg.70680559.eng.abstr
|
DerChirurg.70680559.eng.abstr
|
[
{
"id": "DerChirurg.70680559.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Short-bowel syndrome is a rare problem in surgical practice and its prognosis depends on the length of intestinal remnants and/or the presence of a jejunostomy . In adults long-term total parenteral nutrition ( TPN ) can be avoided if the remaining small bowel is longer than 60-100 cm . In all , 50-60 % of patients in the long-term follow-up are expected to be adequately nourished with oral feeding , 25 % with enteral and parenteral feeding and less than 20 % depend on long-term TPN alone . By using a modified diet ( glutamine , growth hormone ) , intestinal absorption and overall prognosis could even be enhanced . The introduction of home TPN by specialized centres has resulted in a remarkable improvement in quality of life ( > 80 % good ) . The main complications of long-term TPN are sepsis , thrombosis and metabolic disorders . Medical therapy of diarrhoea consists of H2-receptor antagonists ( hypergastrinaemia ) , loperamide and secretion inhibitors ( somatostatin ) . Several surgical procedures have been performed , either to decelerate intestinal transit or to increase the area of intestinal absorption with overall unsatisfactory results . However , in the presence of small-bowel dilatation , promising surgical results ( tapering , stricturoplasty , intestinal lengthening ) have been achieved . There may be advances ( immunosuppression ) in the future that will make intestinal transplantation a good option for some patients ; at present , the 1-year patient and graft survival in around 100 patients was 60 % and 40 % , respectively ."
],
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[
0,
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]
]
}
] |
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DerChirurg.70680583.eng.abstr
|
DerChirurg.70680583.eng.abstr
|
[
{
"id": "DerChirurg.70680583.eng.abstr-passage-0",
"type": "abstract",
"text": [
"There seem to be no gender-specific qualifications for surgery , yet the traditional role model keeps the number of women small . The patriarchal character of surgery has hardly changed whereas social organization , the role of men and women and the division of labor inside the family have all changed . This has opened surgery up for women during the last few decades to a certain degree ."
],
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0,
391
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}
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}
] |
[] |
[] |
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},
{
"id": "DerChirurg.70680583.eng.abstr-s2-r17-t1.1-t4.1",
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}
] |
DerChirurg.70680586.eng.abstr
|
DerChirurg.70680586.eng.abstr
|
[
{
"id": "DerChirurg.70680586.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The prevention of severe late postsplenectomy infection by vaccination and antibiotic prophylaxis is controversial . This paper reviews the literature and presents a protocol for postsplenectomy adults . Prophylaxis should be adapted to the underlying disease . Every patient has to be informed about the consequences of splenectomy . Depending on the underlying disease , vaccination is recommended against pneumococci , Hemophilus influenzae and Neisseria meningitidis . Long-term antibiotic prophylaxis is not advised in adults ."
],
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[
0,
532
]
]
}
] |
[
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"id": "DerChirurg.70680586.eng.abstr-s1-t4",
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[] |
[] |
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DerChirurg.70680591.eng.abstr
|
DerChirurg.70680591.eng.abstr
|
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{
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"text": [
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],
"offsets": [
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0,
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]
]
}
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] |
[] |
[] |
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},
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"id": "DerChirurg.70680591.eng.abstr-s7-r7-t3.1-t2.1",
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}
] |
DerChirurg.70680596.eng.abstr
|
DerChirurg.70680596.eng.abstr
|
[
{
"id": "DerChirurg.70680596.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In 50 lung cancers ( 25 small cell lung cancers , 17 squamous cell carcinomas , 8 adenocarcinomas ) pulmonary , mediastinal and cervical lymph node-metastases were analyzed . Lymph-node \" skipping \" was demonstrated in 46 % of the investigated tumors . In seven of these cases the lymph nodes were skipped , which showed complete hyalinization as a consequence of preexisting anthracosilicosis . In 5 other tumors additional lymph nodes with preserved structure were skipped by the metastatic process . Fibrosis of lymphatic tissue after tuberculosis or exposure to ionizing radiation were further reasons for lymph-node skipping . The skipping of intact lymph nodes can be explained by anatomically demonstrable intra- and perinodal short circuit connections . Apart from that , preexisting lymph node changes ( silicosis , fibrosis ) play an important part."
],
"offsets": [
[
0,
859
]
]
}
] |
[
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"id": "DerChirurg.70680596.eng.abstr-s1-t1",
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"text": [
"lung"
],
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6,
10
]
],
"normalized": [
{
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}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"cancers"
],
"offsets": [
[
11,
18
]
],
"normalized": [
{
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"db_id": "C0006826"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"cell"
],
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[
30,
34
]
],
"normalized": [
{
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"db_id": "C0007634"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"lung"
],
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[
35,
39
]
],
"normalized": [
{
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}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"cancers"
],
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[
40,
47
]
],
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"db_id": "C0006826"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"cell"
],
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[
62,
66
]
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"normalized": [
{
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"db_id": "C0007634"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"carcinomas"
],
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[
67,
77
]
],
"normalized": [
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"db_id": "C0007097"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"adenocarcinomas"
],
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[
82,
97
]
],
"normalized": [
{
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"db_id": "C0001418"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"lymph"
],
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[
137,
142
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024202"
}
]
},
{
"id": "DerChirurg.70680596.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"lung cancers"
],
"offsets": [
[
6,
18
]
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] |
DerChirurg.70680601.eng.abstr
|
DerChirurg.70680601.eng.abstr
|
[
{
"id": "DerChirurg.70680601.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A number of different mapping systems have been published for the lymph-node staging in lung cancer . The use of a reproducible map is an essential prerequisite for correct determination of the TNM status and comparing the surgical results . In order to evaluate the current status of lymph-node mapping and lymph-node dissection in Germany , we performed a mail survey involving 90 hospitals performing operations for lung cancer . Responses were obtained from 61 ( 67.7 % ) hospitals . Currently , the majority of the departments ( 43 % ) use the German staging system ( according to the Deutsche Gesellschaft fuer Thorax- , Herz- und Gefaesschirurgie/Pneumologie ) , 23 % lymph-node mapping according to Naruke , and 25 % an individual description of the resected lymph nodes . The number of resected lymph nodes is reported in 75 % of the departments , the quotient of involved/not involved lymph nodes in 33 % . Mediastinal lymph-node sampling guided by the intraoperative aspect of lymph nodes is performed in 59 % of the departments . A systematic mediastinal \" en-bloc \" resection is accomplished in 41 % . The results of this survey represent the current status of lymph-node mapping and lymphadenectomy in lung cancer in Germany and might be useful for the development of a uniform staging system ."
],
"offsets": [
[
0,
1308
]
]
}
] |
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],
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66,
76
]
],
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}
]
},
{
"id": "DerChirurg.70680601.eng.abstr-s1-t2",
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"lung"
],
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88,
92
]
],
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{
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}
]
},
{
"id": "DerChirurg.70680601.eng.abstr-s1-t3",
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"text": [
"cancer"
],
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93,
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]
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],
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]
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{
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"type": "umlsterm",
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285,
295
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"id": "DerChirurg.70680601.eng.abstr-s3-t2",
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DerChirurg.70680606.eng.abstr
|
DerChirurg.70680606.eng.abstr
|
[
{
"id": "DerChirurg.70680606.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Chest trauma cases benefit to a great degree from adequate , timely initiated and consistent prehospital treatment . However , prehospital determination and evaluation of blunt chest trauma is associated with a high degree of uncertainety . The purpose of our study was to examine and determine , in a collective of 255 trauma patients , the value of additional prehospital pulse oximetric monitoring regarding the optimization of the emergency physician's diagnosis and treatment of blunt chest trauma . We conclude from our findings that , in addition to the physical examination , with the application of pulse oximetry the prehospital diagnosis of lung contusion as well as the early detection of tension pneumothorax are more accurate . Therefore , the combination of physical examination and pulse oximetric monitoring is a requirement for the optimization of prehospital diagnosis and therapy in blunt chest trauma ."
],
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[
0,
923
]
]
}
] |
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DerChirurg.70680613.eng.abstr
|
DerChirurg.70680613.eng.abstr
|
[
{
"id": "DerChirurg.70680613.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A total of 140 patients underwent outpatient laparoscopic cholecystectomy in an outpatient clinic . Evaluation and follow-up of the patients were done prospectively . Population and preoperative data were comparable to published studies of patients operated on in hospitals . There were no serious intra- or postoperative complications . Postoperatively , patients needed less pain medication , were less tired and returned to work earlier than patients after clinical laparoscopic cholecystectomies . Outpatient laparoscopic cholecystectomy offers a good alternative to patients with moderate operative risks ( ASA 1-3 ) . It could reduce costs in the German health system and would be therefore highly cost effective ."
],
"offsets": [
[
0,
720
]
]
}
] |
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15,
23
]
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"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-t2",
"type": "umlsterm",
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"outpatient"
],
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34,
44
]
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"db_id": "C0029921"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"cholecystectomy"
],
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[
58,
73
]
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"db_id": "C0008320"
}
]
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{
"id": "DerChirurg.70680613.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"outpatient"
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80,
90
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"db_id": "C0029921"
}
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{
"id": "DerChirurg.70680613.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"outpatient clinic"
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80,
97
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"db_id": "C0002424"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"Evaluation"
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100,
110
]
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{
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"db_id": "C0220825"
}
]
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{
"id": "DerChirurg.70680613.eng.abstr-s2-t2",
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"patients"
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132,
140
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{
"id": "DerChirurg.70680613.eng.abstr-s3-t1",
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"text": [
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167,
177
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}
]
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{
"id": "DerChirurg.70680613.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"hospitals"
],
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264,
273
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"db_name": "UMLS",
"db_id": "C0019994"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"postoperative"
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308,
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"db_id": "C0032790"
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"id": "DerChirurg.70680613.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"complications"
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{
"id": "DerChirurg.70680613.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"postoperative complications"
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"pain"
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381
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"db_id": "C0030193"
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{
"id": "DerChirurg.70680613.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"medication"
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382,
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"id": "DerChirurg.70680613.eng.abstr-s5-t4",
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{
"id": "DerChirurg.70680613.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
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482,
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{
"id": "DerChirurg.70680613.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"Outpatient"
],
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[
502,
512
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{
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]
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"cholecystectomy"
],
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{
"id": "DerChirurg.70680613.eng.abstr-s6-t3",
"type": "umlsterm",
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"patients"
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571,
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}
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{
"id": "DerChirurg.70680613.eng.abstr-s6-t4",
"type": "umlsterm",
"text": [
"risks"
],
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[
604,
609
]
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{
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"db_id": "C0035647"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-t5",
"type": "umlsterm",
"text": [
"ASA"
],
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[
612,
615
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"db_id": "C0004057"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"costs"
],
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[
640,
645
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{
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"db_id": "C0010186"
},
{
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"db_id": "C0010181"
},
{
"db_name": "UMLS",
"db_id": "C0220812"
}
]
},
{
"id": "DerChirurg.70680613.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"health"
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[
660,
666
]
],
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{
"db_name": "UMLS",
"db_id": "C0018684"
}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680613.eng.abstr-s1-r1-t5.1-t3.1",
"type": "carries_out",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t5",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r2-t3.1-t1.1",
"type": "affects",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r3-t5.1-t1.1",
"type": "manages",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r4-t3.1-t4.1",
"type": "affects",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r5-t5.1-t4.1",
"type": "manages",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t5",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r6-t4.1-t3.1",
"type": "performs",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t4",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r7-t3.1-t2.1",
"type": "affects",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r8-t3.1-t5.1",
"type": "uses",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t3",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r9-t4.1-t5.1",
"type": "uses",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r10-t2.1-t5.1",
"type": "uses",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t5",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r11-t1.1-t5.1",
"type": "uses",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r12-t5.1-t2.1",
"type": "manages",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r13-t1.1-t3.1",
"type": "performs",
"arg1_id": "DerChirurg.70680613.eng.abstr-s7-t1",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s1-r14-t2.1-t3.1",
"type": "performs",
"arg1_id": "DerChirurg.70680613.eng.abstr-s7-t2",
"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s3-r1-t2.1-t3.1",
"type": "uses",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s3-r2-t3.1-t2.1",
"type": "manages",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r1-t5.1-t3.1",
"type": "uses",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r2-t4.1-t5.1",
"type": "performs",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t5",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r3-t5.1-t1.1",
"type": "affects",
"arg1_id": "DerChirurg.70680613.eng.abstr-s6-t5",
"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t1",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r4-t1.1-t5.1",
"type": "performs",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t5",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r5-t5.1-t4.1",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r6-t3.1-t2.1",
"type": "treats",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s5-r7-t5.1-t2.1",
"type": "treats",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r1-t4.1-t2.1",
"type": "evaluation_of",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r2-t1.1-t2.1",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r3-t2.1-t5.1",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r4-t2.1-t3.1",
"type": "affects",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s6-t3",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r5-t3.1-t2.1",
"type": "performs",
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"normalized": []
},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r6-t4.1-t2.1",
"type": "conceptual_part_of",
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},
{
"id": "DerChirurg.70680613.eng.abstr-s6-r7-t2.1-t1.1",
"type": "affects",
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"arg2_id": "DerChirurg.70680613.eng.abstr-s7-t1",
"normalized": []
}
] |
DerChirurg.70680618.eng.abstr
|
DerChirurg.70680618.eng.abstr
|
[
{
"id": "DerChirurg.70680618.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We combined a newly developed ambulatory fiberoptic system for detecting intragastric bilirubin ( Bilitec 2000 , Synectics Medical Inc. , Sweden ) with prolonged measurement of gastroduodenal motility in 10 healthy volunteers and 10 patients following BI resection . Circadian intragastric bilirubin exposure and the total number of tremendous changes of bilirubin absorption ( more than 20 % , over a period of at least 5 min ) were significantly increased in the BI-resected patients ( P 0.05 ) . In patients the interdigestive motility cycle ( IMC ) was characterized by the appearance of several types of abnormally propagated phase III activity fronts . Of the tremendous increases of bilirubin absorption in the patient group , 90.1 % were associated with abnormally propagated phase III activity fronts . In cases of increased duodenogastric reflux , the combination of ambulatory intragastric bilirubin measurement and long-term manometry seems to be feasible to assess motility and reflux simultaneously ."
],
"offsets": [
[
0,
1014
]
]
}
] |
[
{
"id": "DerChirurg.70680618.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"fiberoptic"
],
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[
41,
51
]
],
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{
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"db_id": "C0029144"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"bilirubin"
],
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[
86,
95
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005437"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"Sweden"
],
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[
138,
144
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038995"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"measurement"
],
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[
162,
173
]
],
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{
"db_name": "UMLS",
"db_id": "C0242485"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"volunteers"
],
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[
215,
225
]
],
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{
"db_name": "UMLS",
"db_id": "C0042960"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"patients"
],
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[
233,
241
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"bilirubin"
],
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[
290,
299
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005437"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"bilirubin"
],
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[
355,
364
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005437"
}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"absorption"
],
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}
]
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"id": "DerChirurg.70680618.eng.abstr-s2-t4",
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}
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]
],
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}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"bilirubin"
],
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690,
699
]
],
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{
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}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s4-t2",
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]
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{
"id": "DerChirurg.70680618.eng.abstr-s4-t3",
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"patient"
],
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[
718,
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]
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}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-t1",
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"bilirubin"
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901,
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}
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{
"id": "DerChirurg.70680618.eng.abstr-s5-t2",
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}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"manometry"
],
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]
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}
]
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"duodenogastric reflux"
],
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[
834,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013299"
}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680618.eng.abstr-s1-r1-t4.1-t6.1",
"type": "treats",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s1-t6",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r2-t4.1-t2.1",
"type": "measures",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r3-t3.1-t1.1",
"type": "issue_in",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r4-t6.1-t4.1",
"type": "performs",
"arg1_id": "DerChirurg.70680618.eng.abstr-s1-t6",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r5-t4.1-t1.1",
"type": "issue_in",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r6-t6.1-t4.1",
"type": "interacts_with",
"arg1_id": "DerChirurg.70680618.eng.abstr-s1-t6",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r7-t6.1-t1.1",
"type": "issue_in",
"arg1_id": "DerChirurg.70680618.eng.abstr-s1-t6",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r8-t4.1-t3.1",
"type": "measurement_of",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r9-t2.1-t1.1",
"type": "issue_in",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s1-r10-t4.1-t1.1",
"type": "method_of",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r1-t3.2-t3.1",
"type": "result_of",
"arg1_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r2-t1.1-t2.1",
"type": "interacts_with",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r3-t3.1-t3.2",
"type": "result_of",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"arg2_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r4-t1.1-t3.1",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r5-t3.2-t1.1",
"type": "produces",
"arg1_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r6-t2.1-t3.1",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r7-t1.1-t3.2",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"arg2_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r8-t2.1-t3.2",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r9-t2.1-t1.1",
"type": "interacts_with",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s2-r10-t3.2-t2.1",
"type": "produces",
"arg1_id": "DerChirurg.70680618.eng.abstr-s2-t3",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s4-r1-t1.1-t2.1",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r1-t4.1-t2.1",
"type": "associated_with",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r2-t2.1-t1.1",
"type": "measures",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r3-t2.1-t4.1",
"type": "associated_with",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r4-t2.1-t1.1",
"type": "analyzes",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t2",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r5-t4.1-t1.1",
"type": "produces",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "DerChirurg.70680618.eng.abstr-s5-r6-t1.1-t4.1",
"type": "affects",
"arg1_id": "DerChirurg.70680618.eng.abstr-s5-t1",
"arg2_id": "DerChirurg.70680618.eng.abstr-s5-t4",
"normalized": []
}
] |
DerChirurg.70680630.eng.abstr
|
DerChirurg.70680630.eng.abstr
|
[
{
"id": "DerChirurg.70680630.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Thirty-nine of 63 patients undergoing deep anterior rectal resection received a straight coloanal anastomosis ( CAA ) ; the remaining 24 patients additionally had a colon-j-pouch ( CPA ) constructed . After pouch-anal anastomosis , local septic complications occurred in 12.5 % of patients compared to 20.5 % after coloanal anastomosis . Stool frequency after pouch-anal anastomosis was 3.3 per 24 h compared to 5.2 per 24 h after straight anastomosis within the first year after ileostomy closure ( P = 0.053 ) . Continence was slightly better in the pouch group ( n . s. ) , and anal manometry showed a significant postoperative decrease only in resting pressure after straight coloanal anastomosis ( P 0.001 ) . This study supports the construction of a colon-j-pouch after deep rectal resection , as the pouch-anal anastomosis has fewer local septic complications and seems to improve functional outcome ."
],
"offsets": [
[
0,
909
]
]
}
] |
[
{
"id": "DerChirurg.70680630.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
18,
26
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"anterior"
],
"offsets": [
[
43,
51
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032008"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
137,
145
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"complications"
],
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[
245,
258
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009566"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
281,
289
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"Stool"
],
"offsets": [
[
338,
343
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015733"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"frequency"
],
"offsets": [
[
344,
353
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0376249"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"ileostomy"
],
"offsets": [
[
480,
489
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020883"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"manometry"
],
"offsets": [
[
586,
595
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024751"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"postoperative"
],
"offsets": [
[
617,
630
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032790"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"pressure"
],
"offsets": [
[
656,
664
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0033095"
}
]
},
{
"id": "DerChirurg.70680630.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"complications"
],
"offsets": [
[
854,
867
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009566"
}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680630.eng.abstr-s5-r1-t1.1-t3.1",
"type": "measures",
"arg1_id": "DerChirurg.70680630.eng.abstr-s6-t1",
"arg2_id": "DerChirurg.70680630.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "DerChirurg.70680630.eng.abstr-s5-r2-t1.1-t2.1",
"type": "measures",
"arg1_id": "DerChirurg.70680630.eng.abstr-s6-t1",
"arg2_id": "DerChirurg.70680630.eng.abstr-s5-t2",
"normalized": []
}
] |
DerChirurg.70680638.eng.abstr
|
DerChirurg.70680638.eng.abstr
|
[
{
"id": "DerChirurg.70680638.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The tension band , performed with rigid cerclage wire , is known worldwide as a standard operation technique for the patella fracture as well as for all fractures gaping under strong muscular tensile forces . Eccentricity of power input and transformation of tension into pressure forces are its theoretical rationale . This is a contradiction to the knowledge of engineers . Its disadvantages are : tilting and rolling-out , steps and gaps in the cartilage surface and distraction . Rigid cerclage wire is not a tensile instrument . Corresponding to this , the results are only mediocre . Here we describe a static tension band principle , consisting of axial power input by 2 lateral cables . The very good and good X-ray and functional results amount to 78 % , far exceeding the rate with the conventional wire tension band ."
],
"offsets": [
[
0,
828
]
]
}
] |
[
{
"id": "DerChirurg.70680638.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"wire"
],
"offsets": [
[
49,
53
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005978"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"standard"
],
"offsets": [
[
80,
88
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038137"
},
{
"db_name": "UMLS",
"db_id": "C0175675"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"operation"
],
"offsets": [
[
89,
98
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0543467"
},
{
"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"technique"
],
"offsets": [
[
99,
108
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0025664"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"patella"
],
"offsets": [
[
117,
124
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030647"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"fracture"
],
"offsets": [
[
125,
133
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016658"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"fractures"
],
"offsets": [
[
153,
162
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0016658"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"power"
],
"offsets": [
[
225,
230
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032863"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"pressure"
],
"offsets": [
[
272,
280
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0033095"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"knowledge"
],
"offsets": [
[
351,
360
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0376554"
}
]
},
{
"id": "DerChirurg.70680638.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"engineers"
],
"offsets": [
[
364,
373
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0014279"
}
]
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] |
[] |
[] |
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}
] |
DerChirurg.70680643.eng.abstr
|
DerChirurg.70680643.eng.abstr
|
[
{
"id": "DerChirurg.70680643.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Failure to find the gallbladder at the usual or most common atypical sites during surgery for cholecystolithiasis is a rare but known problem . Although ultrasonography has 95 % sensitivity for the diagnosis of cholelithiasis , occasionally a small contracted gallbladder with stones and chronic cholecystitis will be difficult to visualize and can lead to erroneous interpretation . We report on the case of a patient presenting with abdominal colic and ultrasonographically confirmed cholecystolithiasis . During laparoscopic cholecystectomy , the gallbladder could not be detected . After laparoscopic staging followed by endoscopic retrograde cholangiopancreatography and abdominal computed tomography , agenesis of the gallbladder was confirmed . This method can be considered for diagnosis of gallbladder agenesis without the need for laparotomy and thorough exploration ."
],
"offsets": [
[
0,
878
]
]
}
] |
[
{
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31
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{
"id": "DerChirurg.70680643.eng.abstr-s1-t2",
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"surgery"
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{
"id": "DerChirurg.70680643.eng.abstr-s1-t3",
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],
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{
"id": "DerChirurg.70680643.eng.abstr-s2-t1",
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{
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{
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{
"id": "DerChirurg.70680643.eng.abstr-s2-t6",
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{
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{
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{
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{
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] |
[] |
[] |
[
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{
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},
{
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{
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{
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{
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DerChirurg.70680646.eng.abstr
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DerChirurg.70680646.eng.abstr
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[] |
[] |
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DerChirurg.70680654.eng.abstr
|
DerChirurg.70680654.eng.abstr
|
[
{
"id": "DerChirurg.70680654.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The aim of preoperative risk analysis is to reduce postoperative morbidity and mortality by identification of compromised organ function which can be improved by targeted preoperative measures and problem-oriented postoperative therapy . Ideally , therefore , preoperative risk assessment , influences the timing of the surgical procedure , the choice of the surgical approach , and the postoperative management . Identification of preexisting relevant disorders that may influence the postoperative course is an essential prerequisite of risk analysis . While preoperative risk analysis today gains in importance with the increasing extent of elective surgical procedures , preoperative risk evaluation still plays a minor role in the emergency situation when the given patient-dependent risk usually has to be accepted . Objective risk evaluation depends on the general and nutritional status , the pulmonary , cardio-vascular , hepatic , and renal function , and the cooperation of the patient . These factors , however , clearly have to be seen in relation to the type and extent of the planned surgical procedure . The selection of additional tests of organ function , exceeding the standard tests required prior to any surgical intervention , must be guided by the extent of the planned surgical procedure , the physiologic alterations associated with the surgical procedure , and the suspected underlying organ dysfunction . Generally accepted multifactorial classification systems to identify patients at risk for a wide spectrum of surgical procedures are currently not available . Using the model of esophagectomy in patients with esophageal cancer we could , however , demonstrate that a quantitative assessment of the peri- and postoperative risk based on preoperatively available physiologic parameters is possible and markedly reduces postoperative mortality when applied prospectively . The development and validation of similar risk-score systems for other surgical procedures should be considered ."
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DerChirurg.70680662.eng.abstr
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DerChirurg.70680662.eng.abstr
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"Despite improvements in operative and anesthesiological techniques , respiratory problems in surgical patients have been minimized but not eliminated . In addition to risks which are typical for the individual patient , the perioperative respiratory morbidity is affected by anesthesiological manipulations as well as the operation and the nature of the operation ( elective versus emergency ) . In this paper , after describing anesthesia-associated disturbances of the respiratory situation together with worsening due to the disease in patients with COLD , techniques and methods for therapy , prophylaxis , and prognostic assessment are delineated . Two examples are given for patients with respiratory problems ( abdomino-thoracic esophageal resection as a example of local trauma in patients with numerous preoperative risk factors and acute necrotizing pancreatitis to describe the sequelae of a toxic process ) . The essence of our discussion is that , prognostically , preoperative diagnosis is of reduced value . Only a synopsis of clinical findings together with spirometry and blood gas analysis appears to be relevant . Early mobilization in conjunction with excellent postoperative pain therapy is of utmost importance , which is equivalent to the almost routine placement of a patient controllable epidural analgesia technique . These concepts have shown in the two patient groups described that respiratory morbidity may be reduced significantly . Cooperation between surgeons and anesthesiologists , which is characterized by complete and mutually high competence on both sides , is essential for successfully managing patients at increased respiratory risk ."
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DerChirurg.70680670.eng.abstr
|
DerChirurg.70680670.eng.abstr
|
[
{
"id": "DerChirurg.70680670.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Patients under oral anticoagulation with coumarin derivatives have a variable perioperative thromboembolic risk which necessitates continuation of their thromboembolic prophylaxis during elective and emergency surgery . Because of their better handling unfractionated heparin and low-molecular-weight heparins are used most often for this purpose . The overlapping effect of coumarin and heparin therapy requires a close daily monitoring of the clotting inhibition ( partial thromboplastin time , thromboplastin time , thrombin time ) . In elective surgery coumarin therapy is interrupted 2-3 days preoperatively ; in emergency cases vitamin K or fresh frozen plasma have to be substituted . Patients under heparin therapy or prophylaxis are easier to handle , because the effect of heparin disappears in a few hours after stopping the treatment . In the immediate postoperative phase the heparin application is interrupted for 6 h because of increased bleeding risk . It is important to take into account additional risk factors like the underlying disease , disturbances of platelet function , liver diseases and renal insufficiency ."
],
"offsets": [
[
0,
1136
]
]
}
] |
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DerChirurg.70680675.eng.abstr
|
DerChirurg.70680675.eng.abstr
|
[
{
"id": "DerChirurg.70680675.eng.abstr-passage-0",
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"text": [
"Immunosuppressive therapy and its influence on perioperative pathophysiology present special challenges in the event of surgical intervention . Immunosuppressive agents alter the patient's response to surgical stress and infectious complications . The often masked signs , even in the case of severe infection , require a high index of suspicion to establish the diagnosis . This may result in a fatal delay of therapy . In addition , the immunosuppressed state increases the patient's susceptibility to infection and leads to an impairment of wound healing . Therefore , careful perioperative clinical monitoring of the patient and complete control of the immunosuppressive therapy are mandatory . Elective operations in immunosuppressed patients should be performed with special caution regarding the potential perioperative risks for the patient and the graft . On the other hand , if there is evidence of , for example , an acute abdominal event , a more aggressive approach is required to rapidly establish the diagnosis and institute appropriate therapy . From the surgical point of view , special emphasis should be placed on wound closure and on anastomotic sutures when operating on a patient receiving immunosuppressive therapy ."
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DerChirurg.70680689.eng.abstr
|
DerChirurg.70680689.eng.abstr
|
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"Low resection and intersphincteric extirpation of rectal cancer in the distal third of the rectum has become an accepted sphincter-saving method . From December 1990 to December 1994 , 42 patients ( 17 women and 25 men ) with a mean age of 67.2 years had a low resection or extirpation of the rectum at our institution . Eighteen patients received a transanal sutured anastomosis , 24 a stapler anastomosis . We had a lethality rate of 2.5 % and a anastomotic insufficiency rate of 14 % ."
],
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[
0,
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]
]
}
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] |
[] |
[] |
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DerChirurg.70680693.eng.abstr
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DerChirurg.70680693.eng.abstr
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"id": "DerChirurg.70680693.eng.abstr-passage-0",
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"During the past 7 years 45 patients have been operated upon using the Childs-Phillips method . Of those , 37 were subsequently examined for the study - 7 patients had died in the meantime . None of the deaths occurred as a direct result of transmesenteric small-bowel plication . An early recurrence of intestinal obstruction occurred in 4.4 % and a laparotomy was repeated . During the most recent examinations 86.5 % of those patients checked had ( virtually ) no complaints - 91.9 % based upon the Visick classification . A subtotal intestinal obstruction occurred during the period of the study in 8.1 % of cases , but could be conservatively treated . Up until the most recent examination there were still no instances of a late recurrence . Most intestinal obstruction recurrences are due to errors specific to the technique and are early recurrences . On the basis of our results , we are of the opinion that plication in the presence of existing peritonitis , as well as partial plication , is acceptable ."
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0,
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[] |
[] |
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DerChirurg.70680705.eng.abstr
|
DerChirurg.70680705.eng.abstr
|
[
{
"id": "DerChirurg.70680705.eng.abstr-passage-0",
"type": "abstract",
"text": [
"During the past 10 years ( 1987-1996 ) , 842 laparotomies were performed for pancreatic or periampullary neoplasms ; in 25 patients ( 2.9 % ) a neuroendocrine tumor was diagnosed . In 19 of these 25 patients ( 76 % ) a non-functioning endocrine tumor and in 6 patients ( 24 % ) a hormone-active tumor ( four insulinoma , one gastrinoma , one VIPoma ) was found . Of 19 non-functioning neuroendocrine tumors , 14 were malignant . The resection rate of these malignant tumors was 78.6 % ( 11 of 14 ; 3 resections were palliative ) ; in comparison , the resection rate of ductal pancreatic carcinoma in our hospital was 28.1 % . The probability of 5-year survival amounts to 73 % after surgical resection in malignant endocrine tumors and to 19 % in ductal pancreatic carcinoma ( including palliative resections ) . As it is not always clear whether non-functioning endocrine tumors are benign or malignant , oncological resection is recommended . Adjuvant chemotherapy seems not to be necessary ."
],
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[
0,
994
]
]
}
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] |
[] |
[] |
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] |
DerChirurg.70680710.eng.abstr
|
DerChirurg.70680710.eng.abstr
|
[
{
"id": "DerChirurg.70680710.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Juvenile polyposis was first described by Cronkhite and Canada in 1955. This disease is characterized by juvenile intestinal polyps and ectodermal abnormalities . The etiology of Cronkhite-Canada syndrome ( CCS ) , however , is still not well understood . Interestingly , among patients with CCS a significant correlation ( 16.5 % ) with intestinal carcinomas has been observed . Thus , malignant transformation and/or genetic predisposition may be involved in the initiation of the disease . In the following , epidemiology , symptoms , morphology and therapy of CCS are discussed . Our examinations are based on studies reported in the literature and on a case report of a female patient who developed a colon carcinoma 2 years after initial diagnosis of CCS ."
],
"offsets": [
[
0,
762
]
]
}
] |
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{
"id": "DerChirurg.70680710.eng.abstr-s1-t2",
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"Canada"
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{
"id": "DerChirurg.70680710.eng.abstr-s1-t4",
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"polyps"
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"id": "DerChirurg.70680710.eng.abstr-s2-t3",
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"id": "DerChirurg.70680710.eng.abstr-s4-t2",
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"id": "DerChirurg.70680710.eng.abstr-s4-t4",
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] |
DerChirurg.70680715.eng.abstr
|
DerChirurg.70680715.eng.abstr
|
[
{
"id": "DerChirurg.70680715.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A prospective randomized study was designed to determine the effect of postoperative water contact on tissue healing . A total of 121 patients undergoing open hernia repair was divided into two groups . The first group was permitted to shower postoperatively , allowing the wound to come into direct contact with the water , the second group was instructed to keep the incision dry . Water contact , wound healing and patient satisfaction were assessed . There was no difference in wound healing between the two groups and no manifest infection ."
],
"offsets": [
[
0,
546
]
]
}
] |
[
{
"id": "DerChirurg.70680715.eng.abstr-s1-t1",
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"postoperative"
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71,
84
]
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},
{
"id": "DerChirurg.70680715.eng.abstr-s1-t2",
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"water"
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85,
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s1-t3",
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"text": [
"tissue"
],
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102,
108
]
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]
},
{
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"text": [
"patients"
],
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134,
142
]
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s2-t2",
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"text": [
"open"
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154,
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"hernia"
],
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[
159,
165
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"db_id": "C0019270"
}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"repair"
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166,
172
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],
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}
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},
{
"id": "DerChirurg.70680715.eng.abstr-s3-t1",
"type": "umlsterm",
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"wound"
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s3-t2",
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"text": [
"direct"
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293,
299
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],
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{
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"db_id": "C0700157"
}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"water"
],
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[
317,
322
]
],
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{
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},
{
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"dry"
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378,
381
]
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"Water"
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384,
389
]
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t2",
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"wound"
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400,
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"patient"
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418,
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]
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t4",
"type": "umlsterm",
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"satisfaction"
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426,
438
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],
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t5",
"type": "umlsterm",
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"wound healing"
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400,
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},
{
"id": "DerChirurg.70680715.eng.abstr-s4-t6",
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418,
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},
{
"id": "DerChirurg.70680715.eng.abstr-s5-t1",
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"wound"
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482,
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{
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}
]
},
{
"id": "DerChirurg.70680715.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"infection"
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]
},
{
"id": "DerChirurg.70680715.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"wound healing"
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482,
495
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0043240"
}
]
}
] |
[] |
[] |
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{
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"id": "DerChirurg.70680715.eng.abstr-s4-r6-t1.2-t2.1",
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{
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{
"id": "DerChirurg.70680715.eng.abstr-s4-r8-t1.1-t2.2",
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{
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{
"id": "DerChirurg.70680715.eng.abstr-s4-r10-t1.1-t4.1",
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{
"id": "DerChirurg.70680715.eng.abstr-s5-r1-t1.1-t3.1",
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] |
DerChirurg.70680718.eng.abstr
|
DerChirurg.70680718.eng.abstr
|
[
{
"id": "DerChirurg.70680718.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The unreamed femoral nail ( UFN ) system , with its numerous proximal interlocking options , allows a minimal invasive surgical procedure for the treatment of nearly all femoral fracture patterns . Sixty-six fractures , 5 cases of osteolysis or pathologic fractures , 2 limb shortenings and 1 lengthening ( monorail technique ) and 3 cases of pseudarthrosis were stabilised with the UFN from July 1994 to December 1996. The fractures were analysed according to the AO classification . We found 31 polytrauma patients with an mean ISS of 21.8 and a mean PTS of 25.4. Most of the multiply injured patients ( n = 26 ) were stabilised with the UFN primarily . Follow-up of 44 patients ranged from 4 to 18 months postoperatively . According to our clinical and radiological score the results were excellent in 34 % of cases , good in 36.3 % , poor in 20.4 % and bad in 9 % . Average fracture healing time was about 9.8 weeks ."
],
"offsets": [
[
0,
921
]
]
}
] |
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"text": [
"surgical"
],
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119,
127
]
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"db_id": "C0038895"
}
]
},
{
"id": "DerChirurg.70680718.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"procedure"
],
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128,
137
]
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"db_id": "C0184661"
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}
]
},
{
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"treatment"
],
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146,
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]
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{
"id": "DerChirurg.70680718.eng.abstr-s1-t4",
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"fracture"
],
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178,
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"surgical procedure"
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]
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"db_id": "C0543467"
}
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},
{
"id": "DerChirurg.70680718.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"femoral fracture"
],
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170,
186
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"fractures"
],
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208,
217
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},
{
"id": "DerChirurg.70680718.eng.abstr-s2-t2",
"type": "umlsterm",
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"osteolysis"
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231,
241
]
],
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"db_id": "C0029435"
}
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},
{
"id": "DerChirurg.70680718.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"pathologic"
],
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[
245,
255
]
],
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{
"db_name": "UMLS",
"db_id": "C0205469"
}
]
},
{
"id": "DerChirurg.70680718.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"fractures"
],
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256,
265
]
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}
]
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"id": "DerChirurg.70680718.eng.abstr-s2-t5",
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"limb"
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270,
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"technique"
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}
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},
{
"id": "DerChirurg.70680718.eng.abstr-s2-t7",
"type": "umlsterm",
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"pseudarthrosis"
],
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]
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"db_id": "C0033785"
}
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"fractures"
],
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{
"id": "DerChirurg.70680718.eng.abstr-s2-t9",
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"classification"
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]
},
{
"id": "DerChirurg.70680718.eng.abstr-s2-t10",
"type": "umlsterm",
"text": [
"pathologic fractures"
],
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245,
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"id": "DerChirurg.70680718.eng.abstr-s3-t1",
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{
"id": "DerChirurg.70680718.eng.abstr-s6-t3",
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"db_id": "C0162542"
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]
}
] |
[] |
[] |
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DerChirurg.70680727.eng.abstr
|
DerChirurg.70680727.eng.abstr
|
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{
"id": "DerChirurg.70680727.eng.abstr-passage-0",
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"After a latency period of 20 years , in a 39-year-old Austrian citizen of Chinese origin , a surgically removed rectal carcinoma , as well as the neighboring chronic inflammatory rectal mucosa with various degrees of dysplasia and one positive neighboring lymph node , showed helminthiasis in the histopathological examination , convincing us of a link between carcinoma and chronic helminthiasis . Whereas the etiological context between chronic infection by Schistosoma haematobium and endemic frequent urinary bladder carcinoma is considered a matter of fact , whether of not the incidence of intestinal carcinoma is increased in connection with chronic intestinal schistosomiasis is controversial . The etiological and pathogenetic link between helminthiasis and carcinoma should be considered in the same way as for other related inflammatory large-bowel diseases . In the sequence chronic inflammation - severe dysplasia , the formation of carcinoma could possibly occur . Besides a survey of trematodes parasitology and pathology , the link between rectal carcinoma and Schistosomiasis japonicum is pointed out by means of appropriate literature investigations ."
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0,
1169
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]
}
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] |
[] |
[] |
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"id": "DerChirurg.70680727.eng.abstr-s5-r35-t5.1-t7.1",
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] |
DerChirurg.70680732.eng.abstr
|
DerChirurg.70680732.eng.abstr
|
[
{
"id": "DerChirurg.70680732.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The primitive neuroectodermal tumor is a rare soft tissue neoplasm occurring in children and young adults . It derives from a carcinogeneic alteration of pluripotent neural crest cells , caused by a balanced reciprocal translocation t ( 11 ; 22 ) ( q24;q12). Treatment of this undifferentiated , extremely malignant small cell tumor is carried out in compliance with the soft tissue trail ( CWS ) from the German Society of Pediatric Oncology . Biopsy-proven diagnosis is followed by primary chemotherapy , which in 95 % of cases leads to remission , allowing excision of the remainder of the tumor without mutilation and avoidance of intraoperative tumor cell dissemination . After excision , irradiation of the tumor site and two further sequences of chemotherapy are performed . If PNETs of the paravertebral region cause symptoms of paralysis and immediate surgery is required , postoperative chemotherapy , a second-look operation and irradiation are mandatory . Between 1986 and 1994 , in cooperation with our pediatric and radiotherapy colleagues , we treated ten patients . In four patients ( median age , 14 years ) the PNET originated from the chest wall , in six patients from the paravertebral and retroperitoneal region . Five patients died after 20 months on average , while the remaining five patients are in full remission after 31 , 46 , 50 , 51 and 91 months , respectively ."
],
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0,
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]
}
] |
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] |
[] |
[] |
[
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{
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{
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}
] |
DerChirurg.70680742.eng.abstr
|
DerChirurg.70680742.eng.abstr
|
[
{
"id": "DerChirurg.70680742.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Here , we present the so-called \" Vollmer retractor \" , which can be fixed on to the operating table . It allows an optimal transference of the traction force on to the border of the wound , both in upper and lower abdominal interventions . In this way , as shown by our recent experience , we gain an optimal view of the subdiaphragmatic area and into the small pelvis ."
],
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0,
371
]
]
}
] |
[
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"id": "DerChirurg.70680742.eng.abstr-s2-t1",
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124,
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"db_id": "C0040678"
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{
"id": "DerChirurg.70680742.eng.abstr-s2-t2",
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},
{
"id": "DerChirurg.70680742.eng.abstr-s2-t3",
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{
"id": "DerChirurg.70680742.eng.abstr-s3-t1",
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{
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"db_id": "C0030797"
}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680742.eng.abstr-s2-r1-t3.2-t1.1",
"type": "result_of",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r2-t2.1-t3.2",
"type": "associated_with",
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"arg2_id": "DerChirurg.70680742.eng.abstr-s2-t3",
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},
{
"id": "DerChirurg.70680742.eng.abstr-s2-r3-t1.1-t3.1",
"type": "result_of",
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"arg2_id": "DerChirurg.70680742.eng.abstr-s2-t3",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r4-t3.1-t2.1",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r5-t2.1-t3.1",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r6-t1.1-t3.2",
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},
{
"id": "DerChirurg.70680742.eng.abstr-s2-r7-t3.1-t1.1",
"type": "result_of",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r8-t2.1-t1.1",
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{
"id": "DerChirurg.70680742.eng.abstr-s2-r9-t3.2-t2.1",
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"arg2_id": "DerChirurg.70680742.eng.abstr-s2-t2",
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}
] |
DerChirurg.70680744.eng.abstr
|
DerChirurg.70680744.eng.abstr
|
[
{
"id": "DerChirurg.70680744.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Because of the rare incidence of splenic abscesses and bleeding , only a few cases are described in the literature on percutaneous drainage of splenic abscesses . We report on eight cases ( three male , five female , average age 74.1 +/- 10.76 years ) of percutaneous , sonographically controlled catheter drainage of large splenic abscesses . Results : Percutaneous , sonographically controlled drainage of splenic abscesses was feasible in all eight cases in the last 5 years ( trocar technique , drain : 12-16 F , abscess contents 70-750 ml ) . In seven of eight cases , therapy with percutaneous , sonographically controlled drainage of the splenic abscess and rinsing of the abscess cavity over several days was successful . In two cases , however , a recurrent abscess had to be drained repeatedly with sonographic control , and this was successful . In one case a colitis-related fistula prevented successful drainage of an infected subcapsular splenic hematoma . The following splenectomy , however , proved the infected hematoma to be completely drained . In this study there were no complications like bleeding , injury of pleura or colon . The advantages of percutaneous drainage are : the spleen is not removed ; conservative therapy is beneficial , particularly in multimorbid patients with a high surgical risk ; there is no transmission of bacterias ; the method is safe and effective ."
],
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[
0,
1401
]
]
}
] |
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"id": "DerChirurg.70680744.eng.abstr-s1-t2",
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"id": "DerChirurg.70680744.eng.abstr-s1-t3",
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"id": "DerChirurg.70680744.eng.abstr-s2-t1",
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{
"id": "DerChirurg.70680744.eng.abstr-s2-t2",
"type": "umlsterm",
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"id": "DerChirurg.70680744.eng.abstr-s2-t3",
"type": "umlsterm",
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"id": "DerChirurg.70680744.eng.abstr-s2-t4",
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"id": "DerChirurg.70680744.eng.abstr-s3-t2",
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"id": "DerChirurg.70680744.eng.abstr-s3-t3",
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"id": "DerChirurg.70680744.eng.abstr-s3-t4",
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"id": "DerChirurg.70680744.eng.abstr-s3-t5",
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"id": "DerChirurg.70680744.eng.abstr-s5-t2",
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"id": "DerChirurg.70680744.eng.abstr-s6-t1",
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"id": "DerChirurg.70680744.eng.abstr-s6-t2",
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"id": "DerChirurg.70680744.eng.abstr-s6-t4",
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"id": "DerChirurg.70680744.eng.abstr-s8-t3",
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"id": "DerChirurg.70680744.eng.abstr-s8-t4",
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"id": "DerChirurg.70680744.eng.abstr-s9-t2",
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{
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]
}
] |
[] |
[] |
[
{
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"arg1_id": "DerChirurg.70680744.eng.abstr-s9-t4",
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{
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{
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{
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"type": "conceptual_part_of",
"arg1_id": "DerChirurg.70680744.eng.abstr-s9-t1",
"arg2_id": "DerChirurg.70680744.eng.abstr-s9-t4",
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{
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"type": "associated_with",
"arg1_id": "DerChirurg.70680744.eng.abstr-s9-t5",
"arg2_id": "DerChirurg.70680744.eng.abstr-s9-t4",
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{
"id": "DerChirurg.70680744.eng.abstr-s2-r1-t4.1-t6.1",
"type": "treats",
"arg1_id": "DerChirurg.70680744.eng.abstr-s9-t4",
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DerChirurg.70680753.eng.abstr
|
DerChirurg.70680753.eng.abstr
|
[
{
"id": "DerChirurg.70680753.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Cardiac complications remain an important cause of perioperative morbidity and mortality with noncardiac surgery , despite improvement in surgical techniques and anaesthetic management . Therefore preoperative cardiovascular risk assessment plays a pivotal role in management of patients prior to noncardiac surgery . Thorough history-taking and careful examination are essential to consider further diagnostic steps in order to predict the patient's individual perioperative cardiac risk as accurately as possible . Besides elaboration of medical therapy , cardiac catherization and even balloon angioplasty or bypass surgery must be considered if indicated by preoperative cardiac testing ."
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0,
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}
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] |
[] |
[] |
[
{
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},
{
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},
{
"id": "DerChirurg.70680753.eng.abstr-s2-r4-t3.1-t4.1",
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},
{
"id": "DerChirurg.70680753.eng.abstr-s2-r6-t2.1-t1.1",
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{
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{
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{
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{
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},
{
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},
{
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"arg2_id": "DerChirurg.70680753.eng.abstr-s4-t3",
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}
] |
DerChirurg.70680770.eng.abstr
|
DerChirurg.70680770.eng.abstr
|
[
{
"id": "DerChirurg.70680770.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The classification of renal insufficiency into stages of full compensation , compensated and decompensated retention and terminal renal failure is of importance if patients with impaired renal function are to undergo elective and emergency surgery . Furthermore , it should be established whether the renal disease is stable or progressive . Preoperatively , particular attention should be paid to problems of fluid and electrolyte homoeostasis as well as to acid-base balance . Many drugs should be avoided altogether in patients with kidney disease ."
],
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0,
552
]
]
}
] |
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DerChirurg.70680775.eng.abstr
|
DerChirurg.70680775.eng.abstr
|
[
{
"id": "DerChirurg.70680775.eng.abstr-passage-0",
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"text": [
"A high-risk patient is a challenge to the anaesthesiologist . If surgical intervention is indicated the perioperative anaesthesiological management has to be carefully adapted to the requirements of the patient . If the patient is classified a high-risk at the preoperative anaesthesiological assessment , the therapeutic management has to aim at optimizing the patient's preoperative physical status . Intraoperatively , the minimal monitoring standards have to be extended by addition of specific non-invasive or invasive monitoring techniques to observe the intraoperative cardiovascular or pulmonary function according to the patient's preoperative disease . There are no recommendations about the choice of the anaesthesia techniques ; the decision for general or regional anaesthesia depends on the site of operation and is guided by the individual experience of the anaesthesiologist . During the postoperative period each high-risk patient has to be observed in the intensive care unit to continue intraoperative monitoring and therapy . Patients at risk of postoperative myocardial ischaemia or infarction should be closely monitored for 3-5 days postoperatively . The perioperative risk of morbidity and mortality associated with elective surgical procedures has to be evaluated for each patient and the risk-benefit analysis discussed in a interdisciplinary dialogue involving the surgeon , the patient and the patient's family ."
],
"offsets": [
[
0,
1440
]
]
}
] |
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] |
[] |
[] |
[
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},
{
"id": "DerChirurg.70680775.eng.abstr-s3-r5-t2.1-t3.1",
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{
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},
{
"id": "DerChirurg.70680775.eng.abstr-s8-r48-t11.1-t2.1",
"type": "uses",
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},
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"id": "DerChirurg.70680775.eng.abstr-s8-r49-t9.1-t14.1",
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}
] |
DerChirurg.70680784.eng.abstr
|
DerChirurg.70680784.eng.abstr
|
[
{
"id": "DerChirurg.70680784.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Disturbances in calcium and bone metabolism after gastrectomy have long been recognized . It has been suggested that due to impaired calcium absorption after gastrectomy , serum calcium is decreased , being counterregulated by parathyroid hormone release and 1,25-(OH)2-vitamin D formation . Both parathyroid hormone and 1,25-(OH)2-vitamin D are known to release calcium from bone , resulting in bone mass loss and increased fracture risk in some of the gastrectomized patients . No therapy is currently generally agreed on , although supplementation of vitamin D and calcium has been suggested repeatedly . A review on the current understanding of calcium and bone metabolism after gastrectomy is given ."
],
"offsets": [
[
0,
705
]
]
}
] |
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"calcium"
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]
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}
]
},
{
"id": "DerChirurg.70680784.eng.abstr-s1-t2",
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"bone"
],
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]
],
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{
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}
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},
{
"id": "DerChirurg.70680784.eng.abstr-s1-t3",
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"metabolism"
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}
]
},
{
"id": "DerChirurg.70680784.eng.abstr-s1-t4",
"type": "umlsterm",
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"gastrectomy"
],
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50,
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},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t1",
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"calcium"
],
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]
},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"absorption"
],
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]
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]
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{
"id": "DerChirurg.70680784.eng.abstr-s2-t3",
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"gastrectomy"
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{
"id": "DerChirurg.70680784.eng.abstr-s2-t4",
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"calcium"
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}
]
},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t5",
"type": "umlsterm",
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"parathyroid"
],
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227,
238
]
],
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"db_id": "C0030517"
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}
]
},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t6",
"type": "umlsterm",
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"parathyroid"
],
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227,
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},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t7",
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"parathyroid"
],
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}
]
},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t8",
"type": "umlsterm",
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"hormone"
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}
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},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t9",
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"text": [
"release"
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},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t10",
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"text": [
"serum calcium"
],
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]
},
{
"id": "DerChirurg.70680784.eng.abstr-s2-t11",
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"parathyroid hormone"
],
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227,
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],
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},
{
"id": "DerChirurg.70680784.eng.abstr-s3-t1",
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"parathyroid"
],
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},
{
"id": "DerChirurg.70680784.eng.abstr-s3-t2",
"type": "umlsterm",
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"parathyroid"
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},
{
"id": "DerChirurg.70680784.eng.abstr-s3-t3",
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"id": "DerChirurg.70680784.eng.abstr-s3-t4",
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"id": "DerChirurg.70680784.eng.abstr-s3-t5",
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"id": "DerChirurg.70680784.eng.abstr-s3-t6",
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},
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"id": "DerChirurg.70680784.eng.abstr-s3-t7",
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},
{
"id": "DerChirurg.70680784.eng.abstr-s3-t8",
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"fracture"
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}
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},
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"id": "DerChirurg.70680784.eng.abstr-s4-t5",
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"id": "DerChirurg.70680784.eng.abstr-s5-t4",
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}
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"id": "DerChirurg.70680784.eng.abstr-s5-t5",
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]
},
{
"id": "DerChirurg.70680784.eng.abstr-s5-t6",
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"text": [
"gastrectomy"
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],
"normalized": [
{
"db_name": "UMLS",
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}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680784.eng.abstr-s1-r1-t3.2-t2.1",
"type": "affects",
"arg1_id": "DerChirurg.70680784.eng.abstr-s3-t3",
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{
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"normalized": []
},
{
"id": "DerChirurg.70680784.eng.abstr-s1-r3-t2.1-t3.2",
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{
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"type": "disrupts",
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DerChirurg.70680789.eng.abstr
|
DerChirurg.70680789.eng.abstr
|
[
{
"id": "DerChirurg.70680789.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Germline mutations of the RET proto-oncogene localized on chromosome 10q11.2 are the underlying cause of hereditary medullary thyroid carcinoma . In MEN 2A and FMTC , mutations can be found in exons 10 , 11 , 13 or 14. MEN 2B is characterized by a specific mutation in exon 16. In a significant number of sporadic MTC somatic mutations in codon 918 ( exon 16 ) are detectable . Some rare sporadic MTC present somatic mutations in codons 611 , 634 , 768 and 883. Recently , deletion-insertion of the RET proto-oncogene in exon 11 and a deletion in exon 10 has been found . RET proto-oncogene mutations are not only responsible for the development of the familial MTC , but may also play an important role in the pathogenesis of sporadic MTC . However , the prognostic relevance of these somatic events is still unclear ."
],
"offsets": [
[
0,
819
]
]
}
] |
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] |
[] |
[] |
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DerChirurg.70680794.eng.abstr
|
DerChirurg.70680794.eng.abstr
|
[
{
"id": "DerChirurg.70680794.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The aim of this study was to access the importance of the laparoscopic colorectal resection . Of 131 patients 80 were operated on laparoscopically . The conversion rate was 14 % ( 13/93 ) . A total of 47 patients suffered from cancer . Curative resection was performed in 41 patients ( 87 % ) . For comparison , 48 patients who underwent open resection were used . The complication rate was lower after laparoscopy and no reoperation was performed . Patients recovered quicker and their first oral food intake and bowel movement were earlier . Hospital stay was shorter ( 15.3 vs. 8.1 days ) , and pain at rest and in motion was significantly reduced . Equal numbers of mesenteric lymph nodes were retrieved ; adequate margins of resection could be obtained and the length of resected bowel did not differ . No port metastases were observed . Reduced morbidity , reduced hospital stay , reduced abdominal pain , quicker reconvalescence , and reduced overall health care costs are strong arguments in favor of laparoscopic colectomy ."
],
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0,
1033
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]
}
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[] |
[] |
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DerChirurg.70680806.eng.abstr
|
DerChirurg.70680806.eng.abstr
|
[
{
"id": "DerChirurg.70680806.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In comparison to conventional operating technique endoscopic surgery reveals numerous advantages , particular rapid mobilisation and earlier discharge from observation . For a effective utilization of these advantages , it is desirable to have a efficient postoperative analgesic scheme , wich can be continued into the period after discharge from hospital . In a randomised , prospective double-blind study we investigated the analgesic efficacy of dipyrone in 40 patients , scheduled for endoscopic abdominal surgery ( mainly endoscopic cholecystectomy ) . Patients received before induction of anesthesia either dipyrone ( 1 g/100 ml NaCl i . v. ) or placebo ( 100 ml NaCl i . v. ) . These infusions were repeated 6 h and 12 h after first application . After surgery all patients were allowed to self-administer buprenorphine intravenously from a PCA-pump ( Bolus 30 µg, lockout 5 min in the recovery room , 30 min on the ward ) . Every hour for the first 6 h and after 24 h , cumulated doses of buprenorphine , pain scores ( 0-10 ) , pulse , blood pressure and side effects were recorded . Dipyrone-treated patients had significantly less pain immediately after surgery and used a significantly lower cumulated dose of buprenorphine ( -67 % ; 90 µg vs. 270 µg buprenorphine ) in the first 24 h after surgery ."
],
"offsets": [
[
0,
1313
]
]
}
] |
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DerChirurg.70680811.eng.abstr
|
DerChirurg.70680811.eng.abstr
|
[
{
"id": "DerChirurg.70680811.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Surgical treatment of diffuse peritonitis is applied very variably . There is no question that source control is the most important treatment principle , but the role of additional treatment concepts such as continuous postoperative peritoneal lavage remains controversial . In a prospective survey ( 1993-1996 ) we analyzed the need for additional treatment concepts in our patient material . In 186 patients with diffuse peritonitis we applied the concept of source control and extensive ( 20-30 l ) intraoperative lavage . Additional treatment principles such as continuous postoperative peritoneal lavage ( n = 17 ) or staged lavage ( n = 5 ) were applied only \" on demand \" , namely in 20 patients ( 11 % ) . In 166 patients ( 89 % ) source control of diffuse peritonitis was possible . The mean severity of peritonitis ( n = 186 ) was 28.5 ( range 16-43 ) using the Mannheim Peritonitis Index . The primary cause of peritonitis in our patients was perforation or leakage in the lower GI tract ( 52 % ) . The hospital mortality rate was 12 % in the whole group , and the postoperative morbidity rate was 34 % . We conclude that nowadays , using high-quality intensive care as well as modern antiinfective treatment , only a few patients ( ca. 10 % ) need additional therapy measures such as postoperative lavage . Surgical source control in combination with intraoperative lavage is sufficient in most of the patients with diffuse peritonitis ."
],
"offsets": [
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1449
]
]
}
] |
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{
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DerChirurg.70680816.eng.abstr
|
DerChirurg.70680816.eng.abstr
|
[
{
"id": "DerChirurg.70680816.eng.abstr-passage-0",
"type": "abstract",
"text": [
"For 1 year all patients in the Department of General Surgery who were transferred to the intensive care unit ( n = 237 ) were prospectively studied as to the development of hyponatremia . Relevant hyponatremia developed in 6.3 % of the patients . The lowest sodium concentration observed was 121 mmol/l , the mean duration was 1.2 days . In general , hyponatremia is related to hypovolemia and diuretics are often involved . In no patient were there any clinical consequences ."
],
"offsets": [
[
0,
477
]
]
}
] |
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23
]
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},
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},
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103
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},
{
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"hyponatremia"
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197,
209
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],
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{
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"db_id": "C0020625"
}
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},
{
"id": "DerChirurg.70680816.eng.abstr-s2-t2",
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"patients"
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236,
244
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},
{
"id": "DerChirurg.70680816.eng.abstr-s3-t1",
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"text": [
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258,
264
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{
"id": "DerChirurg.70680816.eng.abstr-s3-t2",
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},
{
"id": "DerChirurg.70680816.eng.abstr-s4-t1",
"type": "umlsterm",
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],
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351,
363
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],
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},
{
"id": "DerChirurg.70680816.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
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],
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389
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],
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"db_id": "C0546884"
}
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},
{
"id": "DerChirurg.70680816.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
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],
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403
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"normalized": [
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[] |
[] |
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] |
DerChirurg.70680821.eng.abstr
|
DerChirurg.70680821.eng.abstr
|
[
{
"id": "DerChirurg.70680821.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We present a case of primary plasmocytoma of the left upper bronchus . Occlusion led to atelectasis of the left upper lobe and subsequent poststenotic pneumonia . Therapy consisted of local excision of the bronchus and postoperative radiotherapy . This type of lung-conserving therapy in a case of primary plasmocytoma has not been described before ."
],
"offsets": [
[
0,
350
]
]
}
] |
[
{
"id": "DerChirurg.70680821.eng.abstr-s1-t1",
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"text": [
"plasmocytoma"
],
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[
29,
41
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032131"
}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"bronchus"
],
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[
60,
68
]
],
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{
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"db_id": "C0006255"
}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s2-t1",
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"text": [
"atelectasis"
],
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[
88,
99
]
],
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{
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"db_id": "C0004144"
}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"pneumonia"
],
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[
151,
160
]
],
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{
"db_name": "UMLS",
"db_id": "C0032285"
}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"Therapy"
],
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[
163,
170
]
],
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{
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"db_id": "C0087111"
},
{
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}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"bronchus"
],
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[
206,
214
]
],
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{
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"db_id": "C0006255"
}
]
},
{
"id": "DerChirurg.70680821.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"postoperative"
],
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[
219,
232
]
],
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[] |
[] |
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DerChirurg.70680829.eng.abstr
|
DerChirurg.70680829.eng.abstr
|
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"id": "DerChirurg.70680829.eng.abstr-passage-0",
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"Acute compartmental syndrome ( CS ) is a surgical emergency . Different conditions in which high non-physiological pressure appears within a closed fascial space reduce the necessary blood perfusion . CS is caused by trauma , burns , bleeding in patients with coagulopathies , arterial injuries , nephrotic syndrome or unusual physical exercise with secondary compartmental swelling . When decompression occurs too late , permanent loss of function and limb contracture may result . In the following paper we report on a case of four-compartmental syndrome in the lower legs of a patient with drug intoxication . After cannabis consumption , the patient fell asleep sitting cross-legged . During our first examination several hours later , the signs of compartmental syndrome with spontaneous pain , turgid swelling and paresis were present . Bilateral skin incision technique was used to gain entrance into the four compartments in both lower legs . Immediately after the operation , the patient showed crush syndrome with high serum creatine kinase activity 140.501 U/l and acute renal failure caused by rhabdomyolysis . Within 2 weeks of haemofiltration and dialysis , a full recovery to a normal serum creatinine level of 0,7 mg/dl was achieved . After emergency treatment and rehabilitation , the patient showed neither vascular nor neural defects ."
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DerChirurg.70680832.eng.abstr
|
DerChirurg.70680832.eng.abstr
|
[
{
"id": "DerChirurg.70680832.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Hydatid disease is caused by the parasitic tapeworm Echinococcus . The larval stage of this parasite can thrive in many parts of the body , most frequently in the liver . Primary bone location is very rare , accounting for less than 2 % of all hydatid lesions . We report on a case of left-sided extended pelvic infestation . The destruction of the hip joint , os pubis , large parts of the ileum and the femoral head made pelvic resection and prosthetic replacement necessary . Recurrence of a hydatid cyst 5 years later in the left groin originating from the proximal femur was treated with second femoral resection and new total hip replacement . Because of instability , the primarily inserted polyacetal pelvic replacement had to be exchanged for a custom-made device fabricated with the aid of computer-aided design ( CAD ) techniques . This surgical procedure was combined with chemotherapy ( mebendazole ) . The necessity of radical resection in osseus hydatid disease is discussed ."
],
"offsets": [
[
0,
991
]
]
}
] |
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DerChirurg.70680837.eng.abstr
|
DerChirurg.70680837.eng.abstr
|
[
{
"id": "DerChirurg.70680837.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Currently laparoscopic surgery is limited by several factors . One of them is the precise handling of optics . Up to now , in our hospital 52 laparoscopic operations have been done with a voice - controlled robot arm to handle the optics in gallbladder , stomach , large bowel and hernia operations . The visual field is determined by the surgeon . In all cases handling of the robot arm was precise and the voice response exact and without technical problems . Twenty-nine operations were done by one operator as \" solo surgeries \" . In 20 further cases there was one assistant . A robot arm can be used successfully without problems by any laparoscopic surgeon in any operating theater ."
],
"offsets": [
[
0,
689
]
]
}
] |
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},
{
"id": "DerChirurg.70680837.eng.abstr-s3-t7",
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"id": "DerChirurg.70680837.eng.abstr-s3-t8",
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{
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] |
[] |
[] |
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DerChirurg.70680840.eng.abstr
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"Max Broedel ( 1870-1941 ) , from Leipzig , Germany , is often referred to in the USA as the father of modern medical illustration and mentioned in the same breath as Leonardo da Vinci or Andreas Vesal . After a classical formal art education in Leipzig he worked in Carl Ludwig's laboratory of physiology and anatomy , where he came in contact with American physicians . In 1894 , the anatomist F. P. Mall convinced him to work for the recently inaugurated Johns Hopkins School of Medicine in Baltimore , where he collaborated with world-famous surgeons such as H. A. Kelly , W. S. Halsted , and H. Cushing . His illustrations were characterized by meticulous observation , both realistic and explanatory intention , technical superiority , and artistic merit . In 1911 he established the first \" Department of Art as applied to Medicine \" . Here , he proved to be an innovative artist , a creative scientist , and an inspiring and skillful instructor . By the time of Broedel's retirement in 1939 , 160 students had graduated as medical illustrators . His pupils spread his principles and style throughout the USA and Canada , and several similar academic programs for medical illustration have been founded in these countries ."
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DerChirurg.70680865.eng.abstr
|
DerChirurg.70680865.eng.abstr
|
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"Intraductal and intraparenchymal hypertension represent the rationale for surgical drainage procedures in the treatment of chronic pancreatitis . \" Simple \" drainage procedures such as longitudinal pancreaticojejunostomy according to Partington-Rochelle have to be distinguished from \" extended \" drainage operations , e . g . the combination of longitudinal pancreaticojejunostomy with limited local excision of the pancreatic head . This \" extended \" drainage procedure according to Frey is just as effective as resective procedures in terms of persistent pain relief and definitive management of pancreatitis-associated complications of adjacent organs , i . e . distal common bile duct and duodenal stenosis . This operation also addresses an inflammatory mass in the pancreatic head . In contrast to \" simple \" drainage procedures the Frey operation allows reliable exclusion of pancreatic carcinoma . With low perioperative morbidity and zero mortality the Frey procedure significantly improves quality of life and leads to social and occupational rehabilitation ."
],
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DerChirurg.70680874.eng.abstr
|
DerChirurg.70680874.eng.abstr
|
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{
"id": "DerChirurg.70680874.eng.abstr-passage-0",
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"In patients with chronic pancreatitis the inflammatory process in the pancreatic head is frequently the pacemaker of the disease . In these cases an inflammatory tumor develops which leads to local complications in half of the patients . Duodenum-preserving pancreatic head resection , contrary to procedures used in the past , offers the possibility to preserve stomach , duodenum , biliary tree , and the insulin secretory capacity . Duodenum-preserving pancreatic head resection is a subtotal resection of the pancreatic head . In a series of 380 patients the hospital mortality rate was 0.8 % , the frequency of reoperation 5.3 % , and the median hospitalisation time 13.9 days . The early postoperative glucose metabolism was deteriorated in 2 % and improved in 9 % of cases . After a median follow-up time of 6 years , 88 % of the patients were completely painfree or suffered pain rarely . Sixty-three percent were gainfully employed ; the late mortality was 8.9 % . Only 10 % of the patients had further bouts of pancreatitis . The decisive advantage of duodenum-preserving pancreatic head resection over Kausch-Whipple resection is preservation of the endocrine pancreatic function and of neighbouring organs ."
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[] |
[] |
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DerChirurg.70680881.eng.abstr
|
DerChirurg.70680881.eng.abstr
|
[
{
"id": "DerChirurg.70680881.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Pancreatic pseudocysts occur as a complication in the natural course of acute or chronic pancreatitis , with a spontaneous resolution rate of 40 % to 60 % . The incidence of pseudocysts in the course of chronic pancreatitis amounts to 60 % . Pseudocysts have to be differentiated from neoplastic or congenital pancreatic cystic lesions . Careful diagnostic work-up including ERCP and CT scanning is mandatory in the management of pancreatic pseudocysts . The indication for treatment depends on the development of symptoms or complications . Pain is present in up to 90 % of all patients , and the rate of complications varies between 2 % and 55 % . Pancreatic pseudocysts are usually an epiphenomenon of chronic pancreatitis . Pancreatic resection therefore represents a causative treatment . New percutaneous and endoscopic techniques for draining pseudocysts are challenging the previous hegemony of the surgeon . However , so far no prospectively collected data are available comparing the results of interventional and surgical drainage procedures . Therefore , in most symptomatic cases surgery is considered the treatment of choice ."
],
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[
0,
1140
]
]
}
] |
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[] |
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DerChirurg.70680892.eng.abstr
|
DerChirurg.70680892.eng.abstr
|
[
{
"id": "DerChirurg.70680892.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A prospective , controlled , randomized trial was conducted in 275 patients with symptomatic gall stone disease , whose history , laboratory data or sonographical findings did not suggest common bile duct stones . Of these patients , 137 did not undergo intraoperative fluoroscopic cholangiography ( IOC ) , but in the remaining 138 patients IOC was attempted . In 111 cases ( 80.4 % ) the biliary system was sufficiently visualized . In 3 patients ( 2.7 % ) calculi in the cystic or common bile duct were diagnosed , which would have been overlooked without IOC . IOC was false-positive in one case . One year after the operation the patients were asked to return for a follow-up examination . Three patients in the group without IOC had had symptomatic passage of a stone , and one had a common bile duct stone removed by endoscopic papillotomy . A retained stone was discussed as etiology for a pancreatitis in a fifth patient in this group . No patient sustained long-term sequelae from the retained common bile duct stones . None of the patients in the IOC group had evidence of cholangiolithiasis at follow-up . There was no difference between the study groups concerning the incidence of post-operative complications . The operations with IOC lasted significantly longer ( 92 +/- 31 min vs 77 +/- 28 min ) . According to our data and those published earlier , the additional financial and logistic expenditure associated with routine IOC is not justified . Patients with the preoperative suspicion of a common bile duct stone should have endoscopic bile duct clearance ( ERCP and EPT ) prior to cholecystectomy ."
],
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]
}
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DerChirurg.70680898.eng.abstr
|
DerChirurg.70680898.eng.abstr
|
[
{
"id": "DerChirurg.70680898.eng.abstr-passage-0",
"type": "abstract",
"text": [
"An often unrecognized but potentially fatal complication , mostly seen in posttraumatic patients under intensive care , is reactive acute cholecystitis . On account of the high specificity of ultrasound diagnosis in the biliary system we decided to examine the ultrasound criteria for early detection of posttraumatic cholecystitis . Ultrasound of the abdomen was performed prospectively , seven times on different days , in each of 40 artificially respirated patients under intensive care conditions over a period of 12 months . The results show that artificial respiration , parenteral feeding and previous trauma can lead to tardive ( 28/40 ) wallthickening or to a three-layered wall of the gallbladder ( 9/40 ) . In 22.5 % of patients ( 9/40 ) we found the sonographic signs of acute cholecystitis . In correlation with the clinical signs , cholecystectomy was indicated in only two patients . The preoperative ultrasonographic findings and clinical signs of 23 patients with the diagnosis of acute reactive cholecystitis were analysed retrospectively . We found good correlation between sonographic and clinical signs of acute cholecystitis in 21 of these 23 patients . Our study shows that the morphological correlate of a thickened three-layered gallbladder wall can occur in the context of systemic alterations , even if there is no underlying cholecystitis . The diagnosis of acute reactive cholecystitis and the indication for cholecystectomy should be based on the synopsis of pathologic and clinical findings ."
],
"offsets": [
[
0,
1523
]
]
}
] |
[
{
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"text": [
"complication"
],
"offsets": [
[
44,
56
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009566"
}
]
},
{
"id": "DerChirurg.70680898.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"patients"
],
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[
88,
96
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680898.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"care"
],
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[
113,
117
]
],
"normalized": [
{
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"db_id": "C0150499"
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},
{
"id": "DerChirurg.70680898.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"cholecystitis"
],
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[
138,
151
]
],
"normalized": [
{
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"db_id": "C0008325"
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},
{
"id": "DerChirurg.70680898.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"intensive care"
],
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]
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"normalized": [
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DerChirurg.70680906.eng.abstr
|
DerChirurg.70680906.eng.abstr
|
[
{
"id": "DerChirurg.70680906.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Cervical leakage , occuring on average in 20-50 % of the patients , is one of the major causes of morbidity following oesophagectomy for cancer . We report on a new technique of gastroplasty , namely fundus rotation gastroplasty which was used in 53 patients . There were 49 patients with oesophageal cancer and 4 with benign lesions . Hospital mortality was 5.7 % ( 3/53 ) and the leakage rate 7.5 % ( 4/53 ) . The advantages of fundus rotation gastroplasty over conventional gastroplasty are the better blood supply and the greater length of the gastric tube . Controlled clinical trials will be necessary to confirm the advantages of fundus rotation gastroplasty versus conventional gastroplasty ."
],
"offsets": [
[
0,
700
]
]
}
] |
[
{
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{
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"causes"
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"id": "DerChirurg.70680906.eng.abstr-s1-t3",
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"morbidity"
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}
]
},
{
"id": "DerChirurg.70680906.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"oesophagectomy"
],
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118,
132
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"id": "DerChirurg.70680906.eng.abstr-s1-t5",
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"cancer"
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"id": "DerChirurg.70680906.eng.abstr-s2-t1",
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"technique"
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{
"id": "DerChirurg.70680906.eng.abstr-s2-t2",
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"gastroplasty"
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{
"id": "DerChirurg.70680906.eng.abstr-s2-t4",
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"gastroplasty"
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216,
228
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"id": "DerChirurg.70680906.eng.abstr-s2-t5",
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"id": "DerChirurg.70680906.eng.abstr-s3-t2",
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"id": "DerChirurg.70680906.eng.abstr-s4-t2",
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"id": "DerChirurg.70680906.eng.abstr-s4-t3",
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}
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{
"id": "DerChirurg.70680906.eng.abstr-s5-t5",
"type": "umlsterm",
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"supply"
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]
},
{
"id": "DerChirurg.70680906.eng.abstr-s5-t6",
"type": "umlsterm",
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"blood supply"
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"id": "DerChirurg.70680906.eng.abstr-s6-t4",
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{
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"db_id": "C0009933"
}
]
}
] |
[] |
[] |
[
{
"id": "DerChirurg.70680906.eng.abstr-s1-r1-t4.1-t5.1",
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},
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},
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},
{
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"type": "conceptual_part_of",
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},
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{
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{
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},
{
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},
{
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},
{
"id": "DerChirurg.70680906.eng.abstr-s3-r1-t2.1-t4.1",
"type": "degree_of",
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},
{
"id": "DerChirurg.70680906.eng.abstr-s3-r2-t2.1-t3.1",
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},
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},
{
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},
{
"id": "DerChirurg.70680906.eng.abstr-s5-r2-t4.1-t6.1",
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},
{
"id": "DerChirurg.70680906.eng.abstr-s5-r3-t4.2-t4.1",
"type": "derivative_of",
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},
{
"id": "DerChirurg.70680906.eng.abstr-s5-r4-t4.1-t3.1",
"type": "location_of",
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{
"id": "DerChirurg.70680906.eng.abstr-s5-r5-t2.1-t5.2",
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{
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},
{
"id": "DerChirurg.70680906.eng.abstr-s5-r10-t4.1-t2.1",
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},
{
"id": "DerChirurg.70680906.eng.abstr-s5-r11-t3.1-t6.1",
"type": "affects",
"arg1_id": "DerChirurg.70680906.eng.abstr-s6-t3",
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"normalized": []
}
] |
DerChirurg.70680910.eng.abstr
|
DerChirurg.70680910.eng.abstr
|
[
{
"id": "DerChirurg.70680910.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In a prospective randomized study on 50 patients undergoing laparoscopic surgery , the safety and feasibility of open access laparoscopy was analyzed and compared to the closed Veress needle technique . Open access laparoscopic surgery was performed in half the time needed for the Veress needle technique with equal safety and without complications or technical disadvantages . Furthermore , open access offers economical advantages , as disposable trocars are no longer needed . Therefore the open access technique is recommended as the standard for laparoscopic operations ."
],
"offsets": [
[
0,
577
]
]
}
] |
[
{
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]
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"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70680910.eng.abstr-s1-t2",
"type": "umlsterm",
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"surgery"
],
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"db_id": "C0038894"
},
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"db_id": "C0038895"
}
]
},
{
"id": "DerChirurg.70680910.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"safety"
],
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[
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]
],
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"db_id": "C0036043"
}
]
},
{
"id": "DerChirurg.70680910.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"open"
],
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[
113,
117
]
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{
"db_name": "UMLS",
"db_id": "C0266061"
}
]
},
{
"id": "DerChirurg.70680910.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"laparoscopy"
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"db_id": "C0031150"
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{
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[] |
[] |
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] |
DerChirurg.70680914.eng.abstr
|
DerChirurg.70680914.eng.abstr
|
[
{
"id": "DerChirurg.70680914.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Following isolated limb perfusion ( ILP ) with TNF and melphalan the damage to muscle tissue and its systemic consequences in terms of myoglobinemia and myoglobinuria as well as the activation of the cytokine cascade were investigated . We measured the compartmental pressure of the limb during and after perfusion and determined the serum changes of myoglobin , creatine kinase ( CK ) , interleukin ( IL ) -6 , IL-1, s-IL-2-receptor, TNF-receptor , and ICAM-1 levels . The compartmental pressure rose significantly during ILP and decreased after reperfusion . Following its course , the decision whether to perform a fasciotomy or not can be more reliably made . Serum myoglobin levels exceeded 200 times normal values and the increase occurred significantly earlier than that of CK , thus enabling judgement of the risk of renal failure ( crush kidney syndrome ) . The elevation of serum IL-1 and IL-6 values correlated with the frequency of cardiopulmonary problems ( hyperdynamic shock ) and facilitated countermaneuvers . Our data , although obtained from ILP with TNF , could be used to monitor toxicity also when other drug regimens are administered ."
],
"offsets": [
[
0,
1158
]
]
}
] |
[
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"limb"
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19,
23
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{
"id": "DerChirurg.70680914.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"perfusion"
],
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[] |
[] |
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DerChirurg.70680929.eng.abstr
|
DerChirurg.70680929.eng.abstr
|
[
{
"id": "DerChirurg.70680929.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Mediastinitis caused by infection with Clostridium perfringens and spontaneous rupture of the esophagus are both life threatening conditions . The combination of these two entities led to septic multiorgan failure in a 38-year-old woman . The patient was treated successfully by esophagectomy and postoperative lavage through a partially open abdomen . The lack of information regarding emesis , the leading symptom of Boerhaave's syndrome , caused delayed diagnosis : the triad of emesis , severe epigastric pain and emphysema of the skin was not established until 30 h after the onset of symptoms ."
],
"offsets": [
[
0,
600
]
]
}
] |
[
{
"id": "DerChirurg.70680929.eng.abstr-s1-t1",
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"Mediastinitis"
],
"offsets": [
[
0,
13
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0025064"
}
]
},
{
"id": "DerChirurg.70680929.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
24,
33
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "DerChirurg.70680929.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"Clostridium"
],
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[
39,
50
]
],
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] |
DerChirurg.70680932.eng.abstr
|
DerChirurg.70680932.eng.abstr
|
[
{
"id": "DerChirurg.70680932.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In the present case of a granular cell tumor an abdomino-thoracal resection of the esophagus was performed in a 41-year-old patient after preoperative diagnosis had suggested esophageal cancer . Granular cell tumors ( Abrikossoff's tumor ) of the esophagus are rather rare tumors of neuroectodermal benign histogenesis . Diagnosis can be obtained by endoscopic and histological study and immunohistochemical forceps biopsy . Because of the peculiar histological feature of the tumor , it can be mistaken for an squamous cell carcinoma ."
],
"offsets": [
[
0,
536
]
]
}
] |
[
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],
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34,
38
]
],
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}
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},
{
"id": "DerChirurg.70680932.eng.abstr-s1-t2",
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],
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44
]
],
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},
{
"id": "DerChirurg.70680932.eng.abstr-s1-t3",
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],
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]
},
{
"id": "DerChirurg.70680932.eng.abstr-s1-t4",
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[] |
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] |
DerChirurg.70680936.eng.abstr
|
DerChirurg.70680936.eng.abstr
|
[
{
"id": "DerChirurg.70680936.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report on a patient who suffered chylothorax 2 months after she had undergone internal fixation of a fracture of her 12th thoracic vertebral body . The pleural effusion was treated by insertion of a chest tube . The chylothorax was managed conservatively . The patient received protein-rich nutrition supplemented with medium-chain triglycerides . As the volume of chylous fluid drained from the pleura had not decreased after 2 weeks , the patient received total parenteral nutrition without any oral intake of calories . Chest X-rays documented the disappearance of the chylothorax . Reexpansion of the lungs was noted , and the costophrenic sinuses could be clearly visualised ."
],
"offsets": [
[
0,
684
]
]
}
] |
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{
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DerChirurg.70680941.eng.abstr
|
DerChirurg.70680941.eng.abstr
|
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],
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0,
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}
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DerChirurg.70680959.eng.abstr
|
DerChirurg.70680959.eng.abstr
|
[
{
"id": "DerChirurg.70680959.eng.abstr-passage-0",
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"text": [
"The tension-free hernioplasty project began in 1984 at the Lichtenstein Hernia Institute . The method consists of complete reinforcement of the inguinal floor with a large sheet of mesh , with adequate mesh tissue interface beyond the boundary of the inguinal floor , and creation of a new internal ring made of prosthesis . The preliminary report on this operation was published in 1989 , with no recurrence at that point in time . Shortly after submission of the report , several recurrences were encountered . Based on the lesson learned from those recurrences , the operation was slightly modified and reported in 1991. Since then , the Lichtenstein technique has gained world-wide popularity . Outcome measures identical to ours and other authors have been achieved by even those surgeons who have no special interest or expertise in herniology . The purpose of this article is to report the current state of the open tension-free hernioplasty for the repair of primary and recurrent inguinal hernias ."
],
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0,
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]
]
}
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[] |
[] |
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DerChirurg.70680965.eng.abstr
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DerChirurg.70680965.eng.abstr
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DerChirurg.70680977.eng.abstr
|
DerChirurg.70680977.eng.abstr
|
[
{
"id": "DerChirurg.70680977.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The value of the minimal invasive approach for treating groin hernias is not yet well defined . The standard treatment for primary hernia repair in Europe is an open approach ( i.e. Shouldice ) without mesh implantation . A mesh may be used to repair a so-called complicated hernia with a complete myopectineal defect , as well as for recurrent and bilateral hernias . These hernias can well be treated laparoscopically despite the fact that the approach is difficult and that there is an increase of direct costs . Whether or not a transabdominal ( TAPP ) or preperitoneal ( TEP ) endoscopic approach is used depends on the type of hernia , the risk to the patient , and the surgeon's experience . Morbidity and long-term follow-up are identical for both techniques ( TAPP and TEP ) . The advantages for TAPP repair are that the technique is simpler , with a large working space and good diagnostic tools ."
],
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[
0,
907
]
]
}
] |
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[] |
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] |
DerChirurg.70680989.eng.abstr
|
DerChirurg.70680989.eng.abstr
|
[
{
"id": "DerChirurg.70680989.eng.abstr-passage-0",
"type": "abstract",
"text": [
"On 1 January 1996 , the implementation of the new recompense system , the Bundespflegesatzverordnung ( BPflV ) , at the Medical University Halle replaced the former German hospital financing system based on clinic-dependent individual prices . This was the beginning of a new price-performance system of the German hospital market . Since then , for all surgical procedures ( catalogue § 301 SGB V ICPM 5061-5064 ) for benign and malignent thyroid diseases a detailed cost analysis has been performed . Our personnel and material inputs were documented on-line in the operating theatre on a special designed cost-analysis record . The cost analysis was based on 14 cases of lobectomy ( average operative costs DM 1886.82 ) , and 20 each of bilateral subtotal thyroidectomy ( average DM 1970.48 ) , unilateral subtotal thyroidectomy with contralateral lobectomy ( average DM 2164.26 ) and total thyroidectomy ( average DM 2396.70 ) respectively . In 12 cases the costs of total thyroidectomy with cervical and transthoracal lymphadenectomy have been analyzed ( average DM 4664.48 ) ."
],
"offsets": [
[
0,
1082
]
]
}
] |
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DerChirurg.70681004.eng.abstr
|
DerChirurg.70681004.eng.abstr
|
[
{
"id": "DerChirurg.70681004.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Today , orthotopic liver transplantation is the treatment of choice for the end-stage of various liver diseases , and a 1-year survival rate of 80 % and a 5-year survival rate of 70 % in elective patients without tumor are reported in international surveys . The liver transplant programme of the Inselspital in Bern is small compared with international centres , which may raise questions about the results and the justification for such a programme . Over a period of 66 months , 62 liver transplantations were performed in 60 patients at the Inselspital . The hospital mortality was 3.3 % , and the 2.5-year overall survival rate was 92 % for elective cases without tumor . After a median follow-up of 30 months , 68 % of all patients were re-integrated in housework or full- or part-time in their profession , and 83 % were independent from the help of others . We conclude that a small liver transplant programme based only on routine resources can achieve results comparable to the international standards ."
],
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}
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] |
DerChirurg.70681011.eng.abstr
|
DerChirurg.70681011.eng.abstr
|
[
{
"id": "DerChirurg.70681011.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Familial amyloid polyneuropathy ( FAP ) is a rare indication for liver transplantation . The excised liver of the FAP patient can be transplanted into a selected patient . In the following report , sequential liver transplantation is described where a 34-year-old female FAP patient received a cadaver donor liver . The excised native liver was transplanted to a 60-year-old male patient suffering from hepatocellular carcinoma in cirrhosis due to hepatitis C."
],
"offsets": [
[
0,
460
]
]
}
] |
[
{
"id": "DerChirurg.70681011.eng.abstr-s1-t1",
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"text": [
"amyloid"
],
"offsets": [
[
9,
16
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0002716"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"polyneuropathy"
],
"offsets": [
[
17,
31
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0152025"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"liver"
],
"offsets": [
[
65,
70
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0345904"
},
{
"db_name": "UMLS",
"db_id": "C0023884"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"transplantation"
],
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[
71,
86
]
],
"normalized": [
{
"db_name": "UMLS",
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},
{
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{
"db_name": "UMLS",
"db_id": "C0040733"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t5",
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"text": [
"amyloid polyneuropathy"
],
"offsets": [
[
9,
31
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0206247"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t6",
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"text": [
"liver transplantation"
],
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[
65,
86
]
],
"normalized": [
{
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}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
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],
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[
0,
31
]
],
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{
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"db_id": "C0206246"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s2-t1",
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"text": [
"liver"
],
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[
101,
106
]
],
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{
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"db_id": "C0345904"
},
{
"db_name": "UMLS",
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}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"patient"
],
"offsets": [
[
118,
125
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"patient"
],
"offsets": [
[
162,
169
]
],
"normalized": [
{
"db_name": "UMLS",
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}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"liver"
],
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[
209,
214
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0345904"
},
{
"db_name": "UMLS",
"db_id": "C0023884"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"transplantation"
],
"offsets": [
[
215,
230
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0029216"
},
{
"db_name": "UMLS",
"db_id": "C0040732"
},
{
"db_name": "UMLS",
"db_id": "C0040733"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"female"
],
"offsets": [
[
264,
270
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0086287"
},
{
"db_name": "UMLS",
"db_id": "C0015780"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"patient"
],
"offsets": [
[
275,
282
]
],
"normalized": [
{
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"db_id": "C0030705"
}
]
},
{
"id": "DerChirurg.70681011.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
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] |
DerChirurg.70681014.eng.abstr
|
DerChirurg.70681014.eng.abstr
|
[
{
"id": "DerChirurg.70681014.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Residual tumor ( R1) was proven at the proximal bronchial resection margin in 88 ( 3.6 % ) of 2464 cases of lung cancer following lung resection and standard lymph node dissection . Postoperative complications ( 8 % ) were : fistula of the bronchial suture line ( n = 7 ) , bleeding ( n = 2 ) and heart luxation ( n = 1 ) . The in-hospital mortality was 16.6 % . Causes of death were : bronchial fistula ( n = 7 ) , erosion of the pulmonary artery ( n = 4 ) , respiratory failure ( n = 1 ) , and empyema ( n = 1 ) . Forty-three patients received postoperative radiation therapy . Median survival of all patients following incomplete resection was 16 months , compared to 37 months following complete resection ( P 0.001 ) . Length of survival was independent of tumor stage , histology , site of infiltration and postoperative radiation . In conclusion , in resection for lung cancer clear margins should be verified by intraoperative frozen section . In the case of residual tumor at the bronchial resection margin , wider resection is mandatory in stage I and II if the patient meets the functional criteria . Even in stage III a and III b prognosis is significantly better after complete resection than R1-resection; the difference , however , is smaller than in lower stages ."
],
"offsets": [
[
0,
1280
]
]
}
] |
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{
"id": "DerChirurg.70681014.eng.abstr-s1-t9",
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] |
DerChirurg.70681020.eng.abstr
|
DerChirurg.70681020.eng.abstr
|
[
{
"id": "DerChirurg.70681020.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Pulmonary sequestrations have no communication with the bronchial tree . Therefore they are usually airless . However , in the presence of a fistula to the esophagus or the stomach , they might contain air or could even be emphysematic . Such a case in a newborn is presented . This very rare anomaly is frequently named \" communicating bronchopulmonary foregut malformation \" . This malformation has to be included in the differential diagnosis of multicystic lung diseases . Diagnosis can be made preoperatively by esophagography and Doppler sonography ."
],
"offsets": [
[
0,
556
]
]
}
] |
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{
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] |
DerChirurg.70681023.eng.abstr
|
DerChirurg.70681023.eng.abstr
|
[
{
"id": "DerChirurg.70681023.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In 386 patients with rectal carcinoma of UICC stage I-III operated on between 1 January 1985 and 31 December 1995 we investigated the influence of the number of dissected lymph nodes on tumor stage and local recurrence retrospectively . We found a significant correlation between the number of lymph nodes dissected and the number of detected lymph node metastases . Following this result we found an increase in UICC stage III ( P = 0.013 ) and pTx pN2 tumors ( P = 0.000 ) in correlation with the number of dissected lymph nodes . Significantly lower rates of local recurrence were found only in UICC stage I and UICC stage II . Overall and in a multivariate analysis the number of dissected lymph nodes had no influence on local recurrence . It was shown that lower local recurrence rates in UICC stage I and II did not depend on therapeutic benefit but on stage migration because of more exact tumor staging . The influence of other surgical factors , especially total mesorectal excision , remains to be discussed ."
],
"offsets": [
[
0,
1020
]
]
}
] |
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DerChirurg.70681029.eng.abstr
|
DerChirurg.70681029.eng.abstr
|
[
{
"id": "DerChirurg.70681029.eng.abstr-passage-0",
"type": "abstract",
"text": [
"From 1994 to March 1997 , 12 patients with 15 drug-related abscesses of the groin were treated at the Surgical Department of Luebeck Medical University . Besides laboratory , serological and microbiological examinations , the standard diagnostic investigation consisted of sonography or duplex sonography . If indicated , the diagnosis was extended to include , for example , clarification of the retroperitoneum by CT . The most common accompanying disease was deep femoral vein thrombosis . Substitution was planned individually . After surgical débridement and perioperative administration of a beta-lactam-protected acylaminopenicillin , open wound treatment was successfully carried out in 13 cases ; secondary closure was performed four times in cases of good compliance . One abscess led to necrotising of the femoral artery ; saphenous vein was interposed because of erosion bleeding and formation of aneurysm . In a second case , the bifurcation was reconstructed with saphenous vein after external resection of an infected false aneurysm and early occlusion . Both defects were covered by rotation of sartorius muscle and mesh graft . On the basis of the treatment concept , a rapid and successful intervention was possible ; complications such as sepsis , amputation or withdrawal delirium did not occur . Resistance against the antibiotic was not observed . In the case of infected aneurysm , we prefer the autogenous saphenous vein graft followed by rotation of sartorius muscle and mesh graft . Ligation or excision leads to high rates of claudication or amputation ; extended reconstructions are threatened by insufficient compliance of the patients ; the use of synthetic grafts is endangered by further bacteraemia or infections ."
],
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[
0,
1747
]
]
}
] |
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[] |
[] |
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] |
DerChirurg.70681035.eng.abstr
|
DerChirurg.70681035.eng.abstr
|
[
{
"id": "DerChirurg.70681035.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A 68-year-old woman suffering from severe upper gastrointestinal bleeding underwent an urgent laparotomy . A necrotizing cholecystitis was found . The source of the bleeding was the eroded cystic artery . Perforation of a giant gallstone led to a fistula into the duodenum . The gallstone was removed from the distal jejunum . The patient's postoperative course was uneventful . Later on a choledochal stenosis had to be treated by stenting . One year after the procedure the patient is alive and well ."
],
"offsets": [
[
0,
503
]
]
}
] |
[
{
"id": "DerChirurg.70681035.eng.abstr-s1-t1",
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"woman"
],
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14,
19
]
],
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}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s1-t2",
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"laparotomy"
],
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94,
104
]
],
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}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s1-t3",
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"gastrointestinal bleeding"
],
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[
48,
73
]
],
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"db_id": "C0017181"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s2-t1",
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"cholecystitis"
],
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[
121,
134
]
],
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{
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"db_id": "C0008325"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s3-t1",
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"text": [
"artery"
],
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196,
202
]
],
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"db_id": "C0003842"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"giant"
],
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[
222,
227
]
],
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{
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"db_id": "C0017547"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"gallstone"
],
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[
228,
237
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0242216"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"fistula"
],
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247,
254
]
],
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}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s4-t4",
"type": "umlsterm",
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"duodenum"
],
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[
264,
272
]
],
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"db_id": "C0013303"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"gallstone"
],
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[
279,
288
]
],
"normalized": [
{
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"db_id": "C0242216"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"jejunum"
],
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[
317,
324
]
],
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]
},
{
"id": "DerChirurg.70681035.eng.abstr-s6-t1",
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],
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341,
354
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],
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}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"stenosis"
],
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402,
410
]
],
"normalized": [
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"db_id": "C0009814"
}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"procedure"
],
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462,
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]
],
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},
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}
]
},
{
"id": "DerChirurg.70681035.eng.abstr-s8-t2",
"type": "umlsterm",
"text": [
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],
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[
476,
483
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
}
] |
[] |
[] |
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{
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{
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{
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},
{
"id": "DerChirurg.70681035.eng.abstr-s4-r9-t1.1-t2.1",
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},
{
"id": "DerChirurg.70681035.eng.abstr-s4-r10-t4.1-t2.1",
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}
] |
DerChirurg.70681053.eng.abstr
|
DerChirurg.70681053.eng.abstr
|
[
{
"id": "DerChirurg.70681053.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Trauma is the leading cause of death for people up to 40 years of age in Germany . Most of the patients were injured in traffic accidents where special injury patterns could be detected : head injuries in bicycle and pedestrian accidents , lower extremity injuries in motorcycle accidents , and chest and pelvis injuries in car accidents . After falls from a height , the most common injuries were fractures of the thoracic and lumbar spine . The treatment of polytrauma patients requires high health care resources and demands sophisticated medical support . It is estimated that every trauma patient costs daily approximately DM 4,700 . It is not only the acute medical care that burdens our social system , but also the long period of rehabilitation and reintegration . The number of preventable trauma deaths can be significantly reduced in special trauma centers , and the high costs could be damaging for smaller hospitals . A plea is made for more preventive meausures and legislative changes to reduce the number of traffic accidents . The medical care of trauma patients should be in special trauma centers ."
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DerChirurg.70681066.eng.abstr
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DerChirurg.70681066.eng.abstr
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[
{
"id": "DerChirurg.70681066.eng.abstr-passage-0",
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"Immunologial complications frequently occur during the clinical course in patients with multiple injuries . The increased release of pro-inflammatory mediators during the immunological response to trauma may lead to the systemic inflammatory response syndrome ( SIRS ) and furthermore , to multisystem organ failure ( MOF ) , which is associated with a mortality of up to 80% . The development of multiple organ failure following major trauma is associated with remote organ failure , the dysfunction of organs which were not initially affected by the traum . This manuscript reviews recent data in experimental trauma research and offers a more detailed evaluation of the immunological findings in trauma patients . In particular , the role of pro- and anti-inflammatory cytokines in the development or SIRS , MOF and ROF is discussed . Despite the enormous progress in clinical immunology and the available data on trauma-induced immune dysfunction , a large number of questions still remain to be answered before the immunological alterations following severe trauma can be beneficially influenced by immunomodulatory therapeutic efforts ."
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DerChirurg.70681071.eng.abstr
|
DerChirurg.70681071.eng.abstr
|
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"The diagnostic strategies in multiple trauma aim at rapid identification of life-threatening injuries , recognition of serious organ lesions , and evaluation of the systemic trauma impact , as well as the resulting host reaction . Besides improvements in the structure and organization , major innovations in imaging techniques have significantly improved and accelerated evaluation of the patient with multiple injuries in the emergency room . Systematic diagnostic work-up , integrated multidisciplinary approach , and defined algorithms for traumatic key symptoms represent the hallmarks of successful emergency room management . In particular , diagnostic work-up of injured body cavities using sonography and helical computed tomography are evaluated ."
],
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0,
757
]
]
}
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[] |
[] |
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] |
DerChirurg.70681076.eng.abstr
|
DerChirurg.70681076.eng.abstr
|
[
{
"id": "DerChirurg.70681076.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Thirty-eight patients with 40 fractures of the thoracic spine and the thoracolumbar junction were treated by a minimally invasive procedure , which includes partial corporectomy , the interposition of a tricortical bone graft and anterior stabilization by plate spondylodesis under thoracosopic control . For 36 patients the operation was successfully performed in a complete thoracoscopic way ; in 2 patients conversion to an open technique was necessary . Two postoperative complications such as a reversible lesion of the thoracodorsalis nerve and a transient irritation of nerve root L1 on the approach side were encountered . Postoperative control by X-ray and CT scan showed correct positioning of the bone graft , as well as the fixation device in all patients . Our experience with this minimally invasive stabilizing procedure for injuries of the thoracic spine and the thoracolumbar junction demonstrated the feasibility of the method . Compared to the open method the benefit of minimally invasive surgery included postoperative pain reduction , shorter hospitalization , early recovery of function and reduced mobidity of the operative approach ."
],
"offsets": [
[
0,
1158
]
]
}
] |
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},
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],
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DerChirurg.70681085.eng.abstr
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DerChirurg.70681085.eng.abstr
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"id": "DerChirurg.70681085.eng.abstr-passage-0",
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"Arthroscopic and open surgery have to be combined for successful surgical therapy of the shoulder joint . A surgeon performing open surgery alone or just using arthroscopic measures cannot cover the full spectrum of modern shoulder surgery . Isolated diagnostic arthroscopy is rarely indicated . Far more common , diagnostic arthroscopy is combined with an operative procedure both to confirm preoperative assessment of pathology and to uncover associated lesions . The results of arthroscopic stabilization of chronic anterior post-traumatic dislocations fail to compare with the high success rates of open procedures . Better patient selection will probably be the key to improving results . In cases of acute traumatic first-time dislocation in young , highly athletic people , arthroscopic repair of the isolated Bankart-Perthes lesion offers the attractive advantage of anatomic reconstruction with minimal soft-tissue dissection . Further indications for arthroscopic measurements of pathologies of the glenohumeral joint are synovectomy in rheumatoid arthritis , capsulotomy in frozen shoulder and tenodesis for lesions of the long head of the biceps . Arthroscopic subacromial decompression according to Ellman is the procedure performed most often and most successfully in the shoulder joint and has overcome the classic Neer open acromioplasty . For smaller tears of the supraspinatus tendon , arthroscopic acromioplasty can be combined with an all arthroscopic suture repair or with mini-open repair . Larger tears of the rotator cuff are still the domain for open reconstructive procedures . In associated or isolated AC joint arthritis , an arthroscopic Mumford procedure can be performed . For chronic calcific tendinitis , isolated arthroscopic excision of the calcium deposit is of great value . Additionally , acromioplasty is needed for true mechanical obstruction of the subacromial space ."
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DerChirurg.70681093.eng.abstr
|
DerChirurg.70681093.eng.abstr
|
[
{
"id": "DerChirurg.70681093.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The treatment of knee joint injuries has seen marked development in the last few years . The surgical trauma of intra-articular fracture reconstruction has been reduced significantly . Retrograde nailing , percutaneous plating and specific exposures to distal femur and proximal tibia fractures have been established . Percutaneous osteosynthesis controlled by arthroscopy or fluoroscopy is widely used for B-fractures of the tibial plateau . Injectable bone mineral cement adds to reduced trauma of surgical treatment of these fractures . In all knee ligament procedures , arthroscopy is obligatory for diagnosting and conducting meniscus surgery . Ligament reconstruction should be performed either arthroscopically or by a limited arthrotomy , the results being comparable at present ."
],
"offsets": [
[
0,
788
]
]
}
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DerChirurg.70681106.eng.abstr
|
DerChirurg.70681106.eng.abstr
|
[
{
"id": "DerChirurg.70681106.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Carpal tunnel syndrome is one of the most common nerve compression syndromes . Nocturnal paresthesia and pain are early symptoms , and hypesthesia and thenar atrophy are late symptoms . These days endoscopic and open operation techniques are available . Minimal trauma after endoscopic release allows early return to work . The endoscopic technique should be performed by experienced surgeons to avoid severe complications ."
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] |
[] |
[] |
[
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}
] |
DerChirurg.70681112.eng.abstr
|
DerChirurg.70681112.eng.abstr
|
[
{
"id": "DerChirurg.70681112.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Phospholipase A2 ( PLA2) is a group of secretory as well as intracellular enzymes that release phopsholipides as an early step in inflammation and play a physiologic role in digestion . In humans , the group of secretory , low-molecular-weight PLA2 ( sPLA2) is differentiated from the cytosolic , high-molecular-weight PLA2 ( cPLA2). The two known cPLA2 mediate the intracellular response to inflammation by releasing arachidonic acid from membrane phospholipids . Secretory pancreatic PLA2 ( sPLA2-I) is a digestive zymogen secreted from pancreatic acinar cells in its inactive form . Activated by trypsin in the duodenum , it is an important digestive enzyme . In acute pancreatitis , circulating sPLA2-I indicates pancreatic injury but is mostly inactive . Synovial-type secretory PLA2 ( sPLA2-II), first isolated from synovial fluid of arthritis patients , is increased in inflammation , after surgery or trauma , and in various inflammatory diseases . Unlike sPLA2-I, its catalytic activity is held responsible for mediating the systemic inflammatory reaction and its complications by regulating the synthesis of prostaglandins , leukotrienes and platelet activating factor . Clinically , sPLA2-II offers new possibilities as an early marker for severe inflammation and predicting systemic complications in severely ill patients ."
],
"offsets": [
[
0,
1335
]
]
}
] |
[
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},
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"id": "DerChirurg.70681112.eng.abstr-s2-t6",
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] |
DerChirurg.70681119.eng.abstr
|
DerChirurg.70681119.eng.abstr
|
[
{
"id": "DerChirurg.70681119.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The retrospective results of carbon prostheses for knee ligament reconstruction in 120 patients , as established by questionnaire , are reported at 10 +/- 2 years follow-up . Eighty patients could also be reviewed clinically . Some 60 % of the patients showed good subjective function at reduced activity level . Complications were seen in 72.5 % of the patients with rupture of the carbon prosthesis and in 68 % of those with synovitis . X-ray showed osteoarthritis in up to 59 % of the patients . Carbon prostheses for collateral ligament reconstruction ( 85 % medial , 5.8 % lateral ) were successful in 75 % of cases . Activity and time seem to be less responsible for failure of the carbon prostheses than the features of growing in . Destruction of the knee joint over time is due to reactive synovitis and catabolic enzyme reaction and correlates with joint effusion and pain . If these problems appear , ( arthroscopic ) resection of the synovia is indicated to interrupt the circulus vitiosus ."
],
"offsets": [
[
0,
1003
]
]
}
] |
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},
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"id": "DerChirurg.70681119.eng.abstr-s1-t2",
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"text": [
"carbon"
],
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]
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},
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],
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],
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[] |
[] |
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DerChirurg.70681137.eng.abstr
|
DerChirurg.70681137.eng.abstr
|
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{
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"The following experimental study was conducted to develop biocompatible methods of osteosynthesis in fractures of the distal radius and to evaluate their stability . A model of dorsal wedge osteotomy in the distal radial metaphysis was used to develop the surgical technique and to test the stability of the alternative methods of osteosynthesis . The concept for this model was based on commercially available materials which were either biodegradable or osteoconductive . Four different forms of biocompatible osteosynthesis were compared to combined Kirschner wire osteosynthesis ( KWO ) , our preferred method of treatment of unstable Colles fracture . Biocompatible osteosynthesis was achieved with an invasivity and stability comparable to that of KWO . In conclusion , injection osteosynthesis exceeded the other biocompatible methods of osteosynthesis in all respects . Regarding the recent developments in injectable materials for osteosynthesis it offers the best perspective for clinical application ."
],
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0,
1012
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}
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] |
[] |
[] |
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DerChirurg.70681146.eng.abstr
|
DerChirurg.70681146.eng.abstr
|
[
{
"id": "DerChirurg.70681146.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The gold standard in the operative treatment of chronic insufficiency of the lateral ligaments of the ankle joint is replacement with a tendon ( tenodesis ) . The disadvantage of this method is limitation of movement . The results of the replacement of ligaments with a periosteal flap are similiar to the results after tenodesis , but the rate of complications is significant lower . We investigated the histological changes in periosteal flaps in patients . We saw an alignment of the collagenous fibers in the periosteal flap 8-12 weeks after the operation . The results are statistically significant . The conclusion is that the periosteal flap in the replacement of ligaments changes into a ligamentlike structure ."
],
"offsets": [
[
0,
720
]
]
}
] |
[
{
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"gold"
],
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4,
8
]
],
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}
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"type": "umlsterm",
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"standard"
],
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17
]
],
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"db_id": "C0038137"
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"db_id": "C0175675"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t3",
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"treatment"
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[
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],
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"db_id": "C0087111"
},
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"db_id": "C0039798"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"ligaments"
],
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[
85,
94
]
],
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{
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}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"ankle"
],
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[
102,
107
]
],
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{
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"db_id": "C0003086"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"joint"
],
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[
108,
113
]
],
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{
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"db_id": "C0022417"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t7",
"type": "umlsterm",
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"tendon"
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]
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]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t8",
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"text": [
"tenodesis"
],
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145,
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}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t9",
"type": "umlsterm",
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"tenodesis"
],
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[
145,
154
]
],
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"db_id": "C0284292"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t10",
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"tenodesis"
],
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145,
154
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},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t11",
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"lateral ligaments"
],
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"db_id": "C0242592"
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]
},
{
"id": "DerChirurg.70681146.eng.abstr-s1-t12",
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"ankle joint"
],
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],
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}
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},
{
"id": "DerChirurg.70681146.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"method"
],
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],
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"db_id": "C0025663"
},
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"db_id": "C0025664"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"movement"
],
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208,
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]
],
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"db_id": "C0026649"
}
]
},
{
"id": "DerChirurg.70681146.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"ligaments"
],
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]
},
{
"id": "DerChirurg.70681146.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"flap"
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{
"id": "DerChirurg.70681146.eng.abstr-s3-t3",
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},
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"id": "DerChirurg.70681146.eng.abstr-s3-t4",
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"tenodesis"
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},
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"id": "DerChirurg.70681146.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"complications"
],
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{
"id": "DerChirurg.70681146.eng.abstr-s4-t1",
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"flaps"
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"patients"
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{
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}
] |
[] |
[] |
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DerChirurg.70681150.eng.abstr
|
DerChirurg.70681150.eng.abstr
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"There is no consensus regarding the clinical significance of conventional two-dimensional ultrasound in the diagnosis of meniscal tears of the knee . Three-dimensional ultrasound spatially reconstructs a transparent image of subsequent ultrasound scans . In an experimental study of 96 menisci , radial and oblique tears were detected more often by three-dimensional ultrasound . In a clinical study of 60 menisci the two- and three-dimensional ultrasound reached a sensitivity of 92 % and 100 % , a specificity of 83 % and 88 % , a positive predictive value of 58 % and 67 % , and a negative predictive value of 98 % and 100 % , respectively . Altogether , there was no statistically significant difference between both methods . The high negative predictive value , however , shows that the three-dimensional ultrasound may be a clinically relevant examination for special questions in the diagnostics of meniscal tears ."
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[] |
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] |
DerChirurg.70681156.eng.abstr
|
DerChirurg.70681156.eng.abstr
|
[
{
"id": "DerChirurg.70681156.eng.abstr-passage-0",
"type": "abstract",
"text": [
"This study investigated to what extent quality of life four years or more after the fracture is determined by initial staging ( Gustilo subclassification , time from injury to arrival at hospital ) , by the therapeutic course ( length of hospital stay , number of operations ) , by complications ( amputation , infection ) and by demographic factors ( gender , age ) . A total of 197 patients after type III open tibial shaft fractures ( type IIIA 70 , type IIIB 85 , type IIIC 42 ) from nine centers volunteered to participate in this study . During patients ' follow-up appointments ( mean duration of follow-up 50 months ) , therapeutic course , pre-surgical staging and demographic data were recorded by the surgeon . Patients were asked to rate quality of life on the Nottingham Health Profile and on a visual analogue scale . Multiple regression analysis ( stepwise ) identified two predictors for reducing overall quality of life ( F-test : P = 0.007 ) : number of operations ( adjusted beta : -0 . 21 ) and age ( adjusted beta : -0 . 17 ) . Other factors showed no significant relationship with overall quality of life or with subscales of the Nottingham Health Profile . These findings indicate a dilemma between two therapeutic goals : good functional outcome , which often requires repeated operations , and quality of life , which suffers under prolonged surgical treatment ."
],
"offsets": [
[
0,
1387
]
]
}
] |
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DerChirurg.70681163.eng.abstr
|
DerChirurg.70681163.eng.abstr
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{
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"The concept of emergency free tissue transfer for severe extremity injuries represents a cutting-edge technology . We discuss our very positive results with this technique . The conceptual reasons for these favorable results , compared with conventional approaches , are also discussed . An initial , radical debridement is the most important part of the operation . This is then followed by osteosynthesis . The correct type of free tissue transfer is chosen according to the requirements of the soft tissue defect . Qualitatively better results with earlier definitive rehabilitation were achieved with free tissue transfer performed during the acute stage of limb wound treatment . The follow-up period ranged from 3 months to 8 years . We experienced neither flap loss , osteomyelitis , nor severe wound infection . Using the modern concept of emergency free tissue transfer , we reduced the rate of flap loss and associated morbidity while achieving a functionally improved reconstruction ."
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[] |
[] |
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] |
DerChirurg.70681170.eng.abstr
|
DerChirurg.70681170.eng.abstr
|
[
{
"id": "DerChirurg.70681170.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Vascular diseases and/or sequelae of various systemic diseases are frequently associated with therapy-resistant soft tissue lesions in the lower extremity . Neurovascular pedicled island flaps without the need for the sacrifice of major vessels offer the possibility to save the lower limb from amputation . The long pedicle allows for a wide , tension-free arc of rotation . Major studies of clinical applications at the critical lower extremity have not been reported yet . 14 patients with chronical ulcerations in problematic areas ( e . g . ankle , tibia ) underwent definitive reconstruction using this flap . Complications were mostly observed at the donor site . In one patient major amputation was neccessary due to the development of sepsis . In all other cases adequate coverage and limb salvage was achieved . Excellent padding , variable size and the modest nature of the flap enlarges the variety of plastic-reconstructive procedures in the lower extremity ."
],
"offsets": [
[
0,
972
]
]
}
] |
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] |
DerChirurg.70681175.eng.abstr
|
DerChirurg.70681175.eng.abstr
|
[
{
"id": "DerChirurg.70681175.eng.abstr-passage-0",
"type": "abstract",
"text": [
"This prospective study served as a quality control of a revision concept for case of post-traumatic infection following open reduction and internal fixation in fracture treatment . It is based on clinical and microbiological criteria and has two aims : ( 1 ) eradication of the infection and avoidance of development of chronic osteitis ; ( 2 ) maintenance of internal fixation , if possible . Thirty-four patients were recruited in this study . Surgical revisions were performed according to a consistant concept ( débridement , irrigation , local chemotherapy , drainage ) in defined time intervals ( 2 days ) . The operation site had to be bacteriologically clean after four revisions . Otherwise , the implant had to be removed . Both aims were reached in 11 cases : management of infection with maintenance of internal fixation . In 23 cases the implant material had to be removed . Nevertheless the infection was eliminated in all these patients without exception . The following risk factors for mandatory implant removal were evaluated : diabetes , arteriosclerosis , alcoholism , nicotine . This revision concept helps in the management of acute postoperative osteitis following ORIF in fracture treatment and in avoiding the development of chronic osteitis ."
],
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0,
1268
]
]
}
] |
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DerChirurg.70681181.eng.abstr
|
DerChirurg.70681181.eng.abstr
|
[
{
"id": "DerChirurg.70681181.eng.abstr-passage-0",
"type": "abstract",
"text": [
"When infection of implants is suspected , optimal management requires accurate confirmation or exclusion of infection . However , in spite of demonstrative clinical signs cultures of smears or chemical parameters of inflammation frequently are ambiguous . Scintigraphy with indium-labeled white blood cells ( WBC ) has been reported to be sensitive and specific in the diagnosis of low-grade sepsis of the musculoskeletal system . Twenty-eight patients with possible infection were prospectively studied . Infection was suspected in 19 cases with total hip joint prosthesis , 14 cases with knee joint prosthesis and 1 case with shoulder joint prosthesis . All of them underwent scanning with indium-111-labeled WBC and subsequently underwent surgery . At surgery infections were determined by means of culture or histologic results . When correlated with culture and histologic results sensitivity of 111-indium-WBC imaging was 89 % , with a specifity of 67 % and a predictive accuracy of 77 % . In patients with rheumatoid arthritis , however , predictive accuracy of 111-indium-labeled WBC imaging was higher than with standard diagnostic methods . The difference was statistically significant ( P 0.05 , 2-test ) . In the patients examined as a whole , predictive accuracy of 111-indium-labeled WBC imaging does not differ from that of standard diagnostic methods . That is why expensive and time-consuming 111-indium-WBC imaging is not justified generally in diagnosis of infection of implants . 111-Indium-WBC imaging is well suited to supplement standard diagnostic methods in patients with rheumatoid arthritis ."
],
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DerChirurg.70681187.eng.abstr
|
DerChirurg.70681187.eng.abstr
|
[
{
"id": "DerChirurg.70681187.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Scaphocapitate fracture syndrome ( SCFS ) as part of perilunar distorsion injuries ( PL , PLF ) in the human wrist is still remarkably rare . The diagnosis is determined by careful physical and radiological examinations , including conventional radiographs . Computed tomography can be helpful in detecting such lesions . In our opinion , the high risk of post-traumatic arthrosis because of carpal instability in a osteoligamental injury requires operative reconstruction in nearly all cases . We report the possibility of operative treatment in a case of scaphocapitate fracture syndrome ( Fenton ) by implantation of 2-mm mini-bone screws , while the use of K-wires or Herbert bone screws has been described in former articles ."
],
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[
0,
731
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]
}
] |
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] |
[] |
[] |
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DerChirurg.70681217.eng.abstr
|
DerChirurg.70681217.eng.abstr
|
[
{
"id": "DerChirurg.70681217.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background : Considering the high recurrence rate after conventional inguinal hernia repair , the totally preperitoneal endoscopic inguinal hernia repair has been used . Methods : The present experience of the authors embraces 1085 patients with a total of 1717 inguinal hernias , including 200 recurrences . The operative technique is described with emphasis on pitfalls and tricks . Results : Analysis of the data concerning the first 403 patients with 1 year complete follow-up reveals a mean ( SEM ) operating time of 42 ( 1.2 ) min for unilateral and 58 ( 1.0 ) min for bilateral hernia repair . Mean ( SEM ) postoperative hospital stay was 2 ( 0.04 ) days . Complication rates during and after operation were 0.3 % and 3.3 % respectively . The morbidity rate at 1 month after operation was 3.5 % . The recurrence rate was 0.3 % at 1-year follow-up . Conclusion : Totally preperitoneal endoscopic inguinal hernia repair is safe and reproducible for any type of primary or recurrent inguinal hernia , even in patients with previous subumbilical surgery or severe systemic disease . Careful follow-up is mandatory to assess the late recurrence rate ."
],
"offsets": [
[
0,
1153
]
]
}
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[] |
[] |
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DerChirurg.70681225.eng.abstr
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"Quality assurance is a concept intended to ensure the quality of a surgical therapy on a defined level . But what is \" quality \" in surgical therapy ? Quality can be described in a lot of different ways . Quality has something to do with taste , especially with individual preferences . The testing of the quality of wine is a good example . Even though this is quite difficult , it can still be done and has been done for hundreds of years . In surgery we are still at the beginning . Discussions regarding the definition of quality , the best method of quality assurance and , not least , who is responsibility for its measurement are well-known obstacles on the path to improvement . Quality has basically little to do with research . It is not a matter of finding the right technique , but of ensuring that the right technique , when found , is correctly used . Defined quality standards will allow this . Quality standards in inguinal hernia surgery are : outstanding comfort directly before and after the therapy , few or no side effects troubling the patient , most of all no disastrous side effects , disaster , low rate of relapse and , in our times , decent economy . The question : \" Is the target to be oriented on the average or must the standard be brought nearer the best performance ? \" has to be answered . Surgery and average performance do not match ; surgical performance cannot be oriented on the average . The next question is : \" Which methods are suitable for this ? \" . The \" tracer method \" is one method , one aspect within quality assurance methods in general . It is designed for obtaining information on the quality of a clinic/department . The obtained data on complication rates , for example ( 10 % ) , and their striking points should above all give insight into the complete department , i . e . , on complication rates of a surgical department in general . The same counts for infection rates or striking points . The essential question remains : \" Who should carry it out ? \" Bureaucrats lacking expertise will buy it . The principle of autonomy , \" expertise connected to competence \" has to be kept when answering the question of who should do it and how . The tracer method , using hernia surgery as a tracer , is not necessarily suitable as a measure of the quality of inguinal hernia surgery . Even though it supplies - as a side effect - information about inguinal hernia surgery , like complication rates ( 10 % ) and relapse operations ( 10 % ) , as well as the varying anaesthetic procedures , or the use for changes in therapeutic procedures , the tracer method is not suitable to sufficiently inform about the quality of inguinal hernia surgery in particular . A further essential aspect when analysing quality assurance - showing up clearly at the moment - is the fact , that \" another \" control will develop if this inactivity remains . In this case the \" controllers \" will certainly not be the surgeons . The nightmare vision of bureaucrats ( insurance companies or other parties ) as controllers is in sight . This would be the same situation as if Michael Schumacher's Ferrari were checked by clerks and not by engineers ."
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DerChirurg.70681235.eng.abstr
|
DerChirurg.70681235.eng.abstr
|
[
{
"id": "DerChirurg.70681235.eng.abstr-passage-0",
"type": "abstract",
"text": [
"From 3 years ' experience with nearly 100 transinguinal preperitoneal mesh prosthesis ( TIPP ) repairs for recurrent inguinal hernia the indication , anesthesia , modification of the technique , and results are reported . After intraoperative classification of the hernia , the TIPP repair is indicated especially in large defects of the posterior wall ( L/M III ) . The procedure is easily performed under local anesthesia . During 52 local TIPP repairs , conversion of anesthesia was never necessary . Important technical details include the requirement for a sufficient size of mesh ( 10 cm x 15 cm ) and a certain caudal and cranial fixation of the prosthesis using at least three interrupted stitches for each . Apart from an increased number of seromas ( 12 % ) in the early postoperative period , the results of the TIPP are comparable with those obtained after Shouldice repair for recurrent hernia . The rate of hematomas , infections , and testicular complications range between 1 % and 3 % . Considering the negative case selection of only large recurrent hernias , the TIPP repair reveals a favourably low 1-year recurrence rate of 1 % ."
],
"offsets": [
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]
}
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[] |
[] |
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DerChirurg.70681241.eng.abstr
|
DerChirurg.70681241.eng.abstr
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[
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"The incidence of local relapse after complete ( R0) resection of solid tumors is largely determined by the skill of the surgeon , whereas metastatic relapse in distant organs is caused by pre- or perioperative systemic dissemination of tumor cells . The presence of individual disseminated tumor cells - e . g . , in bone marrow as indicator organ - can be detected by sensitive immunocytochemical and molecular methods and is increasingly considered as a clinically relevant prognostic indicator . In contrast to solid metastases , isolated micrometastatic tumor cells are appropriate targets for intravenously applied anti-cancer therapeutics because they are easily accessible to macromolecules and immunologic effector cells . The majority of these tumor cells appear to be nonproliferating ( i . e . , in the G0 phase of the cell cycle ) , which may explain the failure of adjuvant chemotherapy . Adjuvant therapeutic strategies aimed at quiescent tumor cells are therefore of increasing interest . This therapeutic rationale has been tested and confirmed in a randomized clinical trial using antibody 17-1A in patients with non-metastatic colorectal carcinoma ( UICC stage III ) . The antibody therapy kills also quiescent tumor cells ( \" dormant cells \" ) and is independent from a potential chemotherapy resistance of the tumor cells . As treatment for minimal residual cancer , the clinical use of antibody therapy could be envisaged in conjunction with chemotherapy , applied either in parallel or sequentially . The aim of this review is to present and discuss the current state of research in the field of diagnosis and therapy of minimal residual cancer ."
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] |
DerChirurg.70681251.eng.abstr
|
DerChirurg.70681251.eng.abstr
|
[
{
"id": "DerChirurg.70681251.eng.abstr-passage-0",
"type": "abstract",
"text": [
"It is generally accepted that most inguinal hernias should be operated electively . This study presents a risk calculation challenging this view . Three strategies are presented : prophylactic indication on principle ( A ) , elective operation in every second case ( B ) , and operation in case of strangulation only ( C ) . On the basis of available epidemiological data it is calculated that , for the male German population aged 65 years and over 69 954 ( A ) , 36 292 ( B ) , and 2630 ( C ) inguinal hernia repairs would be necessary annually ; 167 ( A ) , 145 ( B ) and 123 ( C ) perioperative deaths would occur , connected with 1702 ( A ) , 1373 ( B ) and 1048 ( C ) years of life lost , respectively . Thus , operation of every inguinal hernia would result in a ( small ) reduction of life expectancy . These data provide evidence that in elderly patients the indication for operative treatment of inguinal hernias should depend upon symptoms and suffering . There is no reason to operate on asymptomatic patients because of a presumed risk of strangulation ."
],
"offsets": [
[
0,
1067
]
]
}
] |
[
{
"id": "DerChirurg.70681251.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"hernias"
],
"offsets": [
[
44,
51
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019270"
}
]
},
{
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] |
DerChirurg.70681258.eng.abstr
|
DerChirurg.70681258.eng.abstr
|
[
{
"id": "DerChirurg.70681258.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The objective of our trial was to evaluate the significance and usefulness of sentinel lymphadenectomy ( SLNE ) for the staging of regional lymph nodes in breast cancer patients . The study presented illustrates the method and our results . As has been documentated for melanoma , the first lymph node [ sentinel node ( SLN ) ] to receive lymphatic drainage from a primary tumor is the expected first site of lymph-node metastasis . The database presented includes 12 patients with operable breast cancer and clinically negative lymph nodes . In 11 cases the described method was applicable . In only one case was there no correlation between the histology of the SLN and the axillary specimen . Three SLN were tumor-positive . Successful completion of examination of a large number of patients with a long follow-up has the potential of reducing the number of axillary dissections and of significantly reducing morbidity in the majority of breast cancer patients ."
],
"offsets": [
[
0,
965
]
]
}
] |
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] |
[] |
[] |
[
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{
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"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t7",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r7-t2.1-t4.2",
"type": "affects",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r8-t4.1-t5.1",
"type": "location_of",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t5",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r9-t2.1-t1.1",
"type": "affects",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t1",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r10-t4.2-t3.1",
"type": "uses",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t3",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r11-t2.1-t4.2",
"type": "associated_with",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r12-t4.2-t2.1",
"type": "performs",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r13-t4.1-t2.1",
"type": "location_of",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t4",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r14-t1.1-t2.1",
"type": "performs",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t1",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t2",
"normalized": []
},
{
"id": "DerChirurg.70681258.eng.abstr-s8-r16-t3.1-t1.1",
"type": "property_of",
"arg1_id": "DerChirurg.70681258.eng.abstr-s8-t3",
"arg2_id": "DerChirurg.70681258.eng.abstr-s8-t1",
"normalized": []
}
] |
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