knowledgator/bio-NER-relations · Datasets at Hugging Face

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DerOpthalmologe.90960410.eng.abstr	DerOpthalmologe.90960410.eng.abstr	[ { "id": "DerOpthalmologe.90960410.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Incarceration of the iris is a potential complication following trabeculectomy in primary congenital glaucoma . Although this complication is mentioned in the literature , nothing is reported about the technique of surgical revision ." ], "offsets": [ [ 0, 247 ] ] } ]	[ { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "iris" ], "offsets": [ [ 34, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022077" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "complication" ], "offsets": [ [ 54, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "trabeculectomy" ], "offsets": [ [ 77, 91 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040574" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "congenital" ], "offsets": [ [ 103, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009678" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 114, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "congenital glaucoma" ], "offsets": [ [ 103, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020302" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "complication" ], "offsets": [ [ 139, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 172, 182 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 215, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 228, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "surgical revision" ], "offsets": [ [ 228, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035110" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r1-t4.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r2-t2.1-t6.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r3-t1.1-t6.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r4-t2.1-t6.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r5-t4.1-t2.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r6-t6.1-t4.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r7-t6.1-t2.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r8-t2.1-t4.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r9-t6.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r10-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r11-t2.1-t4.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r12-t2.1-t6.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r13-t4.1-t6.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r14-t1.1-t4.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-r15-t6.1-t2.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-r1-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-r2-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960410.eng.abstr-s2-t3", "normalized": [] } ]
DerOpthalmologe.90960421.eng.abstr	DerOpthalmologe.90960421.eng.abstr	[ { "id": "DerOpthalmologe.90960421.eng.abstr-passage-0", "type": "abstract", "text": [ "The follow-up of central scotomas and fixation - next to visual acuity - are important parameters for the evaluation of new therapies in AMD ." ], "offsets": [ [ 0, 142 ] ] } ]	[ { "id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "scotomas" ], "offsets": [ [ 25, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036454" } ] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "evaluation" ], "offsets": [ [ 106, 116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220825" } ] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "therapies" ], "offsets": [ [ 124, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "central scotomas" ], "offsets": [ [ 17, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0152191" } ] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "visual acuity" ], "offsets": [ [ 57, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042812" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r1-t4.1-t2.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r2-t1.1-t2.1", "type": "co-occurs_with", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r3-t2.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r4-t4.1-t1.1", "type": "co-occurs_with", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r5-t2.1-t1.1", "type": "treats", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r6-t1.1-t4.1", "type": "co-occurs_with", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r7-t3.1-t1.1", "type": "treats", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r8-t2.1-t1.1", "type": "co-occurs_with", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960421.eng.abstr-s1-r9-t1.1-t2.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960421.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960421.eng.abstr-s1-t2", "normalized": [] } ]
DerOpthalmologe.90960428.eng.abstr	DerOpthalmologe.90960428.eng.abstr	[ { "id": "DerOpthalmologe.90960428.eng.abstr-passage-0", "type": "abstract", "text": [ "The accuracy of the spectrometric measurement of the oxygen saturation in retinal vessels is limited by its signal-to-noise ratio . The aim of this study was to investigate the possibility of enhancement of the reflection signal by the use of polarized light ." ], "offsets": [ [ 0, 260 ] ] } ]	[ { "id": "DerOpthalmologe.90960428.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "measurement" ], "offsets": [ [ 34, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242485" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "oxygen" ], "offsets": [ [ 53, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030054" }, { "db_name": "UMLS", "db_id": "C0184633" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "retinal" ], "offsets": [ [ 74, 81 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "vessels" ], "offsets": [ [ 82, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005847" }, { "db_name": "UMLS", "db_id": "C0148346" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "retinal vessels" ], "offsets": [ [ 74, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035330" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 136, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 236, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 253, 258 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r1-t1.1-t2.2", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r2-t2.2-t4.2", "type": "uses", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r3-t4.1-t2.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r4-t1.1-t4.2", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r5-t4.1-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r6-t3.1-t1.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r7-t4.2-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r8-t4.2-t2.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r9-t1.1-t3.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r10-t3.1-t4.2", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r11-t1.1-t3.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r13-t4.2-t3.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r14-t1.1-t4.2", "type": "measures", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r15-t3.1-t4.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r16-t3.1-t4.2", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960428.eng.abstr-s1-r17-t4.2-t1.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960428.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960428.eng.abstr-s2-t1", "normalized": [] } ]
DerOpthalmologe.90960432.eng.abstr	DerOpthalmologe.90960432.eng.abstr	[ { "id": "DerOpthalmologe.90960432.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : To prevent surgically induced astigmatism following clear corneal cataract surgery ." ], "offsets": [ [ 0, 97 ] ] } ]	[ { "id": "DerOpthalmologe.90960432.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "astigmatism" ], "offsets": [ [ 43, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004106" } ] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 79, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 88, 95 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cataract surgery" ], "offsets": [ [ 79, 95 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007389" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r1-t3.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r2-t1.1-t3.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r3-t1.1-t3.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r5-t2.1-t3.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r7-t2.1-t3.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960432.eng.abstr-s1-r8-t3.2-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960432.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960432.eng.abstr-s1-t2", "normalized": [] } ]
DerOpthalmologe.90960437.eng.abstr	DerOpthalmologe.90960437.eng.abstr	[ { "id": "DerOpthalmologe.90960437.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : The first morphological changes in eyes with HIV infection are microvascular disease of the retina with cotton-wool spots and microaneurysms . The study was performed to find out if evidence of disturbances of ocular microcirculation can be established by non-invasive methods ." ], "offsets": [ [ 0, 288 ] ] } ]	[ { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "morphological" ], "offsets": [ [ 20, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543482" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 45, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "HIV" ], "offsets": [ [ 55, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019682" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 59, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 87, 94 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "retina" ], "offsets": [ [ 102, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035298" }, { "db_name": "UMLS", "db_id": "C0035309" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "spots" ], "offsets": [ [ 126, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015230" }, { "db_name": "UMLS", "db_id": "C0312414" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "HIV infection" ], "offsets": [ [ 55, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019693" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "microcirculation" ], "offsets": [ [ 227, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025962" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 279, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r1-t2.3-t4.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r2-t6.1-t2.2", "type": "part_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r3-t2.2-t7.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r4-t7.2-t4.1", "type": 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"type": "degree_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r45-t1.1-t2.2", "type": "part_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r46-t2.2-t5.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r47-t6.1-t7.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r48-t7.1-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r49-t1.1-t7.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r51-t7.1-t4.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r52-t2.2-t6.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r53-t7.2-t6.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r54-t2.3-t7.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-r1-t2.1-t1.1", "type": "measurement_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-r2-t1.1-t2.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] } ]
DerOpthalmologe.90960443.eng.abstr	DerOpthalmologe.90960443.eng.abstr	[ { "id": "DerOpthalmologe.90960443.eng.abstr-passage-0", "type": "abstract", "text": [ "Failures with external DCR have also been attributed to canalicular occlusion . Since 1976 we have documented all patients with surgical reconstruction of occluded canaliculi . The indication , different surgical methods of choice and functional prognosis were evaluated ." ], "offsets": [ [ 0, 272 ] ] } ]	[ { "id": "DerOpthalmologe.90960443.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "DCR" ], "offsets": [ [ 23, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010931" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 114, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 128, 136 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "surgical reconstruction" ], "offsets": [ [ 128, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524865" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 204, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 213, 220 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "choice" ], "offsets": [ [ 224, 230 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008300" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "prognosis" ], "offsets": [ [ 246, 255 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033325" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960443.eng.abstr-s2-r1-t1.1-t2.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-r2-t2.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-r1-t1.1-t2.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-r2-t2.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "normalized": [] } ]
DerOpthalmologe.90960448.eng.abstr	DerOpthalmologe.90960448.eng.abstr	[ { "id": "DerOpthalmologe.90960448.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : After treatment of anterior chamber fibrinous reactions by tissue plasminogen activator ( TPA ) , irreversible corneal opacifications ( calcium phosphate ) have been observed . To understand the mechanism of these opacifications an animal model was developed ." ], "offsets": [ [ 0, 273 ] ] } ]	[ { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 19, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 32, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 72, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "plasminogen" ], "offsets": [ [ 79, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032140" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "TPA" ], "offsets": [ [ 103, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076729" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "calcium" ], "offsets": [ [ 149, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006675" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "phosphate" ], "offsets": [ [ 157, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031603" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "After treatment" ], "offsets": [ [ 13, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001758" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "anterior chamber" ], "offsets": [ [ 32, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003151" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "plasminogen activator" ], "offsets": [ [ 79, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032144" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "calcium phosphate" ], "offsets": [ [ 149, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006711" }, { "db_name": "UMLS", "db_id": "C0006712" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "tissue plasminogen activator" ], "offsets": [ [ 72, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032143" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "animal" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003043" }, { "db_name": "UMLS", "db_id": "C0003062" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "animal model" ], "offsets": [ [ 245, 257 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0599779" } ] } ]	[]	[]	[ { "id": 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"arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t9", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r15-t4.1-t1.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r16-t10.1-t4.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t10", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r17-t3.1-t4.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r18-t1.1-t11.1", "type": "uses", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t11", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r19-t6.1-t4.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r20-t4.1-t12.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t12", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r21-t11.1-t6.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t11", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r22-t4.1-t7.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960448.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-r23-t1.1-t12.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960448.eng.abstr-s2-t1", "arg2_id": 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DerOpthalmologe.90960453.eng.abstr	DerOpthalmologe.90960453.eng.abstr	[ { "id": "DerOpthalmologe.90960453.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : The correction of low to moderate astigmatism is possible today by means of photoablation ( PRK ) , while the treatment of moderate and higher astigmatism still involves refractive keratotomy . Experience has shown that cataract surgery , using modern tunnel techniques with self-healing incisions , results in earlier stability in both the refractive outcome and wound healing . In this study , we attempted to combine the advantages of lamellar keratotomy with those of a pair-wise T-incision as arcuate lamellar keratotomy ( ALK ) ." ], "offsets": [ [ 0, 550 ] ] } ]	[ { "id": "DerOpthalmologe.90960453.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "astigmatism" ], "offsets": [ [ 49, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004106" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 125, 134 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "astigmatism" ], "offsets": [ [ 158, 169 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004106" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 235, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 244, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 274, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "wound" ], "offsets": [ [ 379, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021501" }, { "db_name": "UMLS", "db_id": "C0043250" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "cataract surgery" ], "offsets": [ [ 235, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007389" } ] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "wound healing" ], "offsets": [ [ 379, 392 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960453.eng.abstr-s1-r1-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960453.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960453.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s1-r2-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960453.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960453.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-r1-t1.1-t2.2", "type": "result_of", "arg1_id": "DerOpthalmologe.90960453.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960453.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-r2-t6.1-t2.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960453.eng.abstr-s2-t6", "arg2_id": "DerOpthalmologe.90960453.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960453.eng.abstr-s2-r3-t6.1-t4.2", "type": "result_of", 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DerOpthalmologe.90960470.eng.abstr	DerOpthalmologe.90960470.eng.abstr	[ { "id": "DerOpthalmologe.90960470.eng.abstr-passage-0", "type": "abstract", "text": [ "The presence of ophthalmological journals in the WWW is already very extensive . However , the online presence of these journals and publishing houses are qualitatively and quantitatively very different . Online publications offer many advantages in contrast to conventional publications , as for example low manufacture-expenses and speedy , place- and time-independent availability of information . We assume , that online publications will not replace printpublications , but represents a meaningful supplement of the previous offer of information ." ], "offsets": [ [ 0, 552 ] ] } ]	[ { "id": "DerOpthalmologe.90960470.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "journals" ], "offsets": [ [ 33, 41 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162443" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "WWW" ], "offsets": [ [ 49, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282111" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "journals" ], "offsets": [ [ 120, 128 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162443" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "publishing" ], "offsets": [ [ 133, 143 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034037" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "publications" ], "offsets": [ [ 212, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034036" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "contrast" ], "offsets": [ [ 250, 258 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0110625" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "publications" ], "offsets": [ [ 275, 287 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034036" } ] }, { "id": "DerOpthalmologe.90960470.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "publications" ], "offsets": [ [ 425, 437 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034036" } ] } ]	[]	[]	[]
DerOpthalmologe.90960489.eng.abstr	DerOpthalmologe.90960489.eng.abstr	[ { "id": "DerOpthalmologe.90960489.eng.abstr-passage-0", "type": "abstract", "text": [ "In recent years good results after treatment of different superficial corneal pathologies with the excimer laser 193 nm have been reported . Thiel-Behnke dystrophy is a hereditary form of anterior stromal dystrophy , a promising layer for successful phototherapeutic keratectomy ( PTK ) . This type of dystrophy was first described in 1967 in Kiel ." ], "offsets": [ [ 0, 349 ] ] } ]	[ { "id": "DerOpthalmologe.90960489.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 35, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "pathologies" ], "offsets": [ [ 78, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 107, 112 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "after treatment" ], "offsets": [ [ 29, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001758" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "form" ], "offsets": [ [ 180, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 188, 196 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "PTK" ], "offsets": [ [ 281, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033681" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960489.eng.abstr-s1-r1-t1.1-t4.1", "type": "isa", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-r2-t1.1-t3.1", "type": "uses", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-r3-t3.1-t1.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s1-r4-t4.1-t1.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s2-r1-t1.1-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960489.eng.abstr-s2-r2-t3.1-t1.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960489.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960489.eng.abstr-s2-t1", "normalized": [] } ]
DerOpthalmologe.90960494.eng.abstr	DerOpthalmologe.90960494.eng.abstr	[ { "id": "DerOpthalmologe.90960494.eng.abstr-passage-0", "type": "abstract", "text": [ "Lid-loading with precious metals , described by Illig in 1958 , has become increasingly important . Because of its good functional and cosmetic results this method is superior to tarsorrhaphy . Furthermore , lid-loading can be combined with additional surgical techniques to achieve more dynamic lid-closure . In a prospective study we examined the results after lid-loading and discuss postoperative changes of the cornea ." ], "offsets": [ [ 0, 424 ] ] } ]	[ { "id": "DerOpthalmologe.90960494.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "metals" ], "offsets": [ [ 26, 32 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025552" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "cosmetic" ], "offsets": [ [ 135, 143 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010164" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 157, 163 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 252, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 261, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 387, 400 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "cornea" ], "offsets": [ [ 416, 422 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010031" }, { "db_name": "UMLS", "db_id": "C0010034" } ] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "prospective study" ], "offsets": [ [ 315, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033522" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960494.eng.abstr-s4-r2-t3.1-t2.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960494.eng.abstr-s4-t3", "arg2_id": "DerOpthalmologe.90960494.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s4-r3-t2.2-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960494.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960494.eng.abstr-s4-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960494.eng.abstr-s4-r4-t3.1-t1.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960494.eng.abstr-s4-t3", "arg2_id": "DerOpthalmologe.90960494.eng.abstr-s4-t1", "normalized": [] } ]
DerOpthalmologe.90960498.eng.abstr	DerOpthalmologe.90960498.eng.abstr	[ { "id": "DerOpthalmologe.90960498.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Applanation tonometry in eyes with pathological corneae can often not be performed or delivers rather questionable results . We report on our 4-year experience with electronic intraocular needle tonometry ." ], "offsets": [ [ 0, 219 ] ] } ]	[ { "id": "DerOpthalmologe.90960498.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "tonometry" ], "offsets": [ [ 25, 34 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040420" } ] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 38, 42 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "corneae" ], "offsets": [ [ 61, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010031" }, { "db_name": "UMLS", "db_id": "C0010034" } ] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "electronic" ], "offsets": [ [ 178, 188 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013850" } ] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "needle" ], "offsets": [ [ 201, 207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027551" } ] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "tonometry" ], "offsets": [ [ 208, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040420" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r1-t3.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r2-t3.2-t2.3", "type": "affects", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r3-t2.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r5-t2.2-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r6-t2.1-t2.3", "type": "part_of", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r7-t2.2-t3.2", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r9-t3.2-t2.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r10-t2.1-t3.2", "type": "location_of", 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"id": "DerOpthalmologe.90960498.eng.abstr-s1-r15-t3.2-t2.2", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r16-t1.1-t3.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r17-t1.1-t2.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r19-t2.2-t3.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s1-r20-t2.3-t3.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s2-r1-t3.1-t2.1", "type": "uses", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960498.eng.abstr-s2-r2-t3.1-t1.1", "type": "uses", "arg1_id": "DerOpthalmologe.90960498.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960498.eng.abstr-s2-t1", "normalized": [] } ]
DerOpthalmologe.90960503.eng.abstr	DerOpthalmologe.90960503.eng.abstr	[ { "id": "DerOpthalmologe.90960503.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The incidence and course of intraoperative and postoperative complications of LASIK were investigated ." ], "offsets": [ [ 0, 116 ] ] } ]	[ { "id": "DerOpthalmologe.90960503.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "incidence" ], "offsets": [ [ 17, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220856" }, { "db_name": "UMLS", "db_id": "C0021149" } ] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 60, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 74, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "LASIK" ], "offsets": [ [ 91, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0752094" } ] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "postoperative complications" ], "offsets": [ [ 60, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032787" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960503.eng.abstr-s1-r1-t5.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960503.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960503.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-r2-t1.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960503.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960503.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960503.eng.abstr-s1-r3-t3.1-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960503.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960503.eng.abstr-s1-t5", "normalized": [] } ]
DerOpthalmologe.90960509.eng.abstr	DerOpthalmologe.90960509.eng.abstr	[ { "id": "DerOpthalmologe.90960509.eng.abstr-passage-0", "type": "abstract", "text": [ "The main advantage of the bilateral medial rectus faden operation ( posterior fixation suture ) for the treatment of essential infantile esotropia is the low occurrence of delayed consecutive exotropia . Nevertheless , this unwanted complication also occasionally occurs after a faden operation ." ], "offsets": [ [ 0, 296 ] ] } ]	[ { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "operation" ], "offsets": [ [ 56, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 68, 77 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 104, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "esotropia" ], "offsets": [ [ 137, 146 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014877" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "occurrence" ], "offsets": [ [ 158, 168 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243132" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "exotropia" ], "offsets": [ [ 192, 201 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015310" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "complication" ], "offsets": [ [ 233, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "faden" ], "offsets": [ [ 279, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015540" } ] }, { "id": "DerOpthalmologe.90960509.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "operation" ], "offsets": [ [ 285, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] } ]	[]	[]	[ { 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DerOpthalmologe.90960513.eng.abstr	DerOpthalmologe.90960513.eng.abstr	[ { "id": "DerOpthalmologe.90960513.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : In cases of esotropia combined with a high AC/A ratio , partly accommodative convergence excess or with nonaccommodative convergence excess , two methods of surgical therapy are possible : recession of the medial recti ( Parks ) and retroequatorial myopexy ( Cueppers ) . Our aim was to answer the question whether retroequatorial myopexy alone and in combination with bimedial recession are appropriate methods of reducing the strabismic angle at near and distant fixation to values under 10 PD and near-distance disparity to less than 10 PD to form the basis for single binocular vision without bifocals ." ], "offsets": [ [ 0, 617 ] ] } ]	[ { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "esotropia" ], "offsets": [ [ 22, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014877" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 156, 163 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 167, 175 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 176, 183 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "convergence excess" ], "offsets": [ [ 87, 105 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0271380" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "convergence excess" ], "offsets": [ [ 131, 149 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0271380" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 286, 289 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 414, 421 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "values" ], "offsets": [ [ 487, 493 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042295" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "near-distance" ], "offsets": [ [ 510, 523 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012751" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "single" ], "offsets": [ [ 575, 581 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087136" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 592, 598 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "binocular vision" ], "offsets": [ [ 582, 598 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042794" } ] } 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DerOpthalmologe.90960522.eng.abstr	DerOpthalmologe.90960522.eng.abstr	[ { "id": "DerOpthalmologe.90960522.eng.abstr-passage-0", "type": "abstract", "text": [ "Acute syphilitic posterior placoid chorioretinitis ( ASPPC ) has been described as a rare chorioretinal manifestation in patients with secondary syphilis . The fundus changes may simulate other chorioretinal disorders and thus delay an accurate diagnosis and initiation of appropriate pharmacological therapy ." ], "offsets": [ [ 0, 310 ] ] } ]	[ { "id": "DerOpthalmologe.90960522.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 17, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "chorioretinitis" ], "offsets": [ [ 35, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008513" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 121, 129 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 135, 144 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "syphilis" ], "offsets": [ [ 145, 153 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039128" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "disorders" ], "offsets": [ [ 208, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 245, 254 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 301, 308 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r1-t4.1-t3.1", "type": "occurs_in", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r2-t4.2-t3.1", "type": "occurs_in", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r3-t4.1-t2.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r4-t1.1-t4.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r5-t2.1-t3.1", "type": "occurs_in", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r7-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r9-t2.1-t4.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s1-r10-t1.1-t4.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-r1-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-r2-t2.1-t3.1", "type": "precedes", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-r3-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-r4-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960522.eng.abstr-s2-r5-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960522.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960522.eng.abstr-s2-t2", "normalized": [] } ]
DerOpthalmologe.90960529.eng.abstr	DerOpthalmologe.90960529.eng.abstr	[ { "id": "DerOpthalmologe.90960529.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Isolated trauma of the optic nerve usually occurs in association with blunt skull trauma involving fractures of the skull and optic canal , but rarely occurs from blunt ocular trauma ." ], "offsets": [ [ 0, 199 ] ] } ]	[ { "id": "DerOpthalmologe.90960529.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "trauma" ], "offsets": [ [ 24, 30 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021501" }, { "db_name": "UMLS", "db_id": "C0043251" } ] }, { "id": "DerOpthalmologe.90960529.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "optic" ], "offsets": [ [ 38, 43 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029144" } ] }, { "id": "DerOpthalmologe.90960529.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "nerve" ], "offsets": [ [ 44, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027769" } ] }, { "id": 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DerOpthalmologe.90960570.eng.abstr	DerOpthalmologe.90960570.eng.abstr	[ { "id": "DerOpthalmologe.90960570.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Research into the molecular and genetic basis of disease is continually expanding . How does the increasing knowledge about the genetic basis of eye diseases contribute to the development of new therapeutic strategies ?" ], "offsets": [ [ 0, 232 ] ] } ]	[ { "id": "DerOpthalmologe.90960570.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Research" ], "offsets": [ [ 13, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035168" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 62, 69 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 121, 130 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "eye" ], "offsets": [ [ 158, 161 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 162, 170 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 189, 200 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 208, 219 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "eye diseases" ], "offsets": [ [ 158, 170 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015397" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960570.eng.abstr-s1-r1-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960570.eng.abstr-s2-t2", "arg2_id": 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"type": "result_of", "arg1_id": "DerOpthalmologe.90960570.eng.abstr-s2-t6", "arg2_id": "DerOpthalmologe.90960570.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-r23-t4.1-t6.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960570.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960570.eng.abstr-s2-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960570.eng.abstr-s2-r25-t2.2-t6.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960570.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960570.eng.abstr-s2-t6", "normalized": [] } ]
DerOpthalmologe.90960578.eng.abstr	DerOpthalmologe.90960578.eng.abstr	[ { "id": "DerOpthalmologe.90960578.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Multifocal intraocular lenses ( MIOLs ) have been implanted with good results for several years . Because the light is distributed between two or more focuses , there is slight light reduction for every picture . Capsular fibrosis can cause additional reduction of the amount of light to the retina ." ], "offsets": [ [ 0, 315 ] ] } ]	[ { "id": "DerOpthalmologe.90960578.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "lenses" ], "offsets": [ [ 38, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023308" }, { "db_name": "UMLS", "db_id": "C0023317" }, { "db_name": "UMLS", "db_id": "C0023318" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "intraocular lenses" ], "offsets": [ [ 26, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023311" }, { "db_name": "UMLS", "db_id": "C0023319" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 125, 130 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 192, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "fibrosis" ], "offsets": [ [ 237, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016059" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 294, 299 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "retina" ], "offsets": [ [ 307, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035298" }, { "db_name": "UMLS", "db_id": "C0035309" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960578.eng.abstr-s1-r1-t2.1-t2.2", "type": "uses", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s1-r2-t2.2-t1.3", "type": "isa", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s1-t2", "arg2_id": 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"arg1_id": "DerOpthalmologe.90960578.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s1-r8-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s1-r9-t1.3-t1.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s3-r1-t3.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960578.eng.abstr-s3-r2-t1.1-t3.2", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960578.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960578.eng.abstr-s3-t3", "normalized": [] }, { "id": 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DerOpthalmologe.90960583.eng.abstr	DerOpthalmologe.90960583.eng.abstr	[ { "id": "DerOpthalmologe.90960583.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : In the present study we evaluated the influence of topical miotics on intraocular pressure and the blood-aqueous barrier after uncomplicated phacoemulsification and PC-IOL implantation ." ], "offsets": [ [ 0, 199 ] ] } ]	[ { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "miotics" ], "offsets": [ [ 72, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026207" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "pressure" ], "offsets": [ [ 95, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033095" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "blood-aqueous" ], "offsets": [ [ 112, 125 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "phacoemulsification" ], "offsets": [ [ 154, 173 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282545" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "implantation" ], "offsets": [ [ 185, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029976" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "intraocular pressure" ], "offsets": [ [ 83, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021888" } ] }, { "id": "DerOpthalmologe.90960583.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "blood-aqueous barrier" ], "offsets": [ [ 112, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282544" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960583.eng.abstr-s1-r1-t5.1-t6.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960583.eng.abstr-s1-t5", 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DerOpthalmologe.90960587.eng.abstr	DerOpthalmologe.90960587.eng.abstr	[ { "id": "DerOpthalmologe.90960587.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : In therapy-resistant fibrin reactions within the anterior chamber , especially following combined cataract and glaucoma surgery , injection of TPA is indicated . We report our results ." ], "offsets": [ [ 0, 198 ] ] } ]	[ { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "therapy-resistant" ], "offsets": [ [ 16, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "fibrin" ], "offsets": [ [ 34, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015982" }, { "db_name": "UMLS", "db_id": "C0060327" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 62, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 111, 119 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 124, 132 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 133, 140 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "injection" ], "offsets": [ [ 143, 152 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021485" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "TPA" ], "offsets": [ [ 156, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076729" } ] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "anterior chamber" ], "offsets": [ [ 62, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003151" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r1-t9.1-t4.1", "type": "location_of", "arg1_id": 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"DerOpthalmologe.90960587.eng.abstr-s1-t8", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r49-t5.1-t6.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r50-t5.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r51-t5.1-t6.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r52-t5.1-t8.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t8", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r53-t9.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t9", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "normalized": [] } ]
DerOpthalmologe.90960594.eng.abstr	DerOpthalmologe.90960594.eng.abstr	[ { "id": "DerOpthalmologe.90960594.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The recently described \" APC resistance \" caused by a mutant form of factor V ( factor V Leiden ) is the most frequent cause of hereditary thrombosis . This study was carried out to investigate the association between activated protein C resistance and central retinal vein occlusion ( CRVO ) . We evaluated the prevalence of APC resistance in patients with CRVO , patients with a history of deep-vein thrombosis , and a healthy control group ." ], "offsets": [ [ 0, 457 ] ] } ]	[ { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "APC" ], "offsets": [ [ 38, 41 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003315" }, { "db_name": "UMLS", "db_id": "C0162832" }, { "db_name": "UMLS", "db_id": "C0033036" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "form" ], "offsets": [ [ 74, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "cause" ], "offsets": [ [ 132, 137 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "thrombosis" ], "offsets": [ [ 152, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040053" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "APC resistance" ], "offsets": [ [ 38, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600433" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "factor V" ], "offsets": [ [ 82, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015498" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "factor V" ], "offsets": [ [ 93, 101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015498" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "factor V Leiden" ], "offsets": [ [ 93, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0380964" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "association" ], "offsets": [ [ 211, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004083" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "protein" ], "offsets": [ [ 241, 248 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "retinal" ], "offsets": [ [ 274, 281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "vein" ], "offsets": [ [ 282, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042449" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "protein C" ], "offsets": [ [ 241, 250 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033621" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "retinal vein" ], "offsets": [ [ 274, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035327" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "retinal vein occlusion" ], "offsets": [ [ 274, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035328" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 325, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "APC" ], "offsets": [ [ 339, 342 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003315" }, { "db_name": "UMLS", "db_id": "C0162832" }, { "db_name": "UMLS", "db_id": "C0033036" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 357, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 378, 386 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "history" ], "offsets": [ [ 394, 401 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019664" }, { "db_name": "UMLS", "db_id": "C0019665" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "deep-vein" ], "offsets": [ [ 405, 414 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042449" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "thrombosis" ], "offsets": [ [ 415, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040053" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 442, 449 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "APC resistance" ], "offsets": [ [ 339, 353 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600433" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t10", "type": "umlsterm", "text": [ "deep-vein thrombosis" ], "offsets": [ [ 405, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0149871" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t11", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 442, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960594.eng.abstr-s1-r1-t1.1-t6.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960594.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960594.eng.abstr-s3-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-r2-t6.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960594.eng.abstr-s3-t6", "arg2_id": "DerOpthalmologe.90960594.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-r3-t1.2-t6.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960594.eng.abstr-s3-t1", 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DerOpthalmologe.90960600.eng.abstr	DerOpthalmologe.90960600.eng.abstr	[ { "id": "DerOpthalmologe.90960600.eng.abstr-passage-0", "type": "abstract", "text": [ "In spite of the availability of cyclocryodestructive laser therapy there still appears to be an indication for cyclocryotherapy in different kinds of glaucoma ." ], "offsets": [ [ 0, 160 ] ] } ]	[ { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 53, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 59, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 150, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960600.eng.abstr-s1-r1-t1.1-t2.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960600.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960600.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960600.eng.abstr-s1-r2-t2.1-t1.1", "type": "uses", "arg1_id": "DerOpthalmologe.90960600.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960600.eng.abstr-s1-t1", "normalized": [] } ]
DerOpthalmologe.90960605.eng.abstr	DerOpthalmologe.90960605.eng.abstr	[ { "id": "DerOpthalmologe.90960605.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : If the surgeon cannot find the tendon of the superior oblique muscle in the right place , he has to change his operative plans intraoperatively . Different procedures are recommended : reinsertion of the superior oblique in the right place , recession of the inferior oblique muscle , and operations on the vertical muscles of the same or the yoke eye . No quantitative recommendations on the surgical amount are mentioned in the literature ." ], "offsets": [ [ 0, 457 ] ] } ]	[ { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 46, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "muscle" ], "offsets": [ [ 77, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 91, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "plans" ], "offsets": [ [ 136, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 171, 181 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "reinsertion" ], "offsets": [ [ 200, 211 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035139" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 243, 248 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "muscle" ], "offsets": [ [ 291, 297 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "operations" ], "offsets": [ [ 304, 314 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "muscles" ], "offsets": [ [ 331, 338 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "eye" ], "offsets": [ [ 363, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "recommendations" ], "offsets": [ [ 385, 400 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034866" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 408, 416 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 445, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960605.eng.abstr-s1-r1-t2.1-t4.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-r2-t1.1-t4.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-r3-t3.1-t4.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r1-t5.2-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r2-t3.1-t7.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "arg2_id": 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"DerOpthalmologe.90960605.eng.abstr-s2-r9-t7.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r10-t7.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r11-t3.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r12-t3.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r13-t7.1-t3.1", "type": "surrounds", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r14-t7.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r15-t1.1-t7.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r16-t7.1-t5.2", "type": "surrounds", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r17-t5.2-t7.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "normalized": [] }, { "id": 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"arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r26-t3.1-t5.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-r27-t5.1-t7.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-r1-t2.1-t1.1", "type": "isa", "arg1_id": "DerOpthalmologe.90960605.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "normalized": [] } ]
DerOpthalmologe.90960611.eng.abstr	DerOpthalmologe.90960611.eng.abstr	[ { "id": "DerOpthalmologe.90960611.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The rehabilitation of low vision patients is of increasing importance since the number of these patients has grown rapidly . We wanted to evaluate the actual spectrum of patients concerning age and diagnoses and the appropriate low vision aids ( LVA ) in 1 year ." ], "offsets": [ [ 0, 276 ] ] } ]	[ { "id": "DerOpthalmologe.90960611.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "rehabilitation" ], "offsets": [ [ 17, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034991" }, { "db_name": "UMLS", "db_id": "C0034992" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 39, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 46, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 109, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "low vision" ], "offsets": [ [ 35, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042798" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 183, 191 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "age" ], "offsets": [ [ 203, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "aids" ], "offsets": [ [ 252, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021588" }, { "db_name": "UMLS", "db_id": "C0001175" } ] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "low vision" ], "offsets": [ [ 241, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042798" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r1-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r2-t4.1-t1.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r3-t5.1-t1.2", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r4-t5.1-t4.1", "type": "occurs_in", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r5-t5.1-t3.1", "type": "occurs_in", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r6-t3.1-t1.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r7-t1.1-t4.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r8-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r9-t5.1-t1.2", "type": "result_of", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r10-t1.1-t1.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r11-t1.2-t5.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s1-r12-t1.1-t3.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960611.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960611.eng.abstr-s2-r1-t1.1-t4.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960611.eng.abstr-s2-t1", "arg2_id": 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DerOpthalmologe.90960640.eng.abstr	DerOpthalmologe.90960640.eng.abstr	[ { "id": "DerOpthalmologe.90960640.eng.abstr-passage-0", "type": "abstract", "text": [ "Backround : Although cataract surgery is highly developed today , there are still problems such as secondary cataract . In polishing the posterior capsule lens , epithelial cells often remain , causing secondary cataracts . Additionally , there are the problems of tissue heating and endothelial cell loss during phacoemulsification by ultrasound . This could be another field for improvement of cataract surgery by using the waterjet ." ], "offsets": [ [ 0, 436 ] ] } ]	[ { "id": "DerOpthalmologe.90960640.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 21, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 30, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 99, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 109, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "cataract surgery" ], "offsets": [ [ 21, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007389" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 137, 146 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "capsule" ], "offsets": [ [ 147, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006935" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "lens" ], "offsets": [ [ 155, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023308" }, { "db_name": "UMLS", "db_id": "C0023317" }, { "db_name": "UMLS", "db_id": "C0023318" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 173, 178 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 202, 211 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "cataracts" ], "offsets": [ [ 212, 221 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "epithelial cells" ], "offsets": [ [ 162, 178 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014597" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 265, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "heating" ], "offsets": [ [ 272, 279 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018851" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 296, 300 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "phacoemulsification" ], "offsets": [ [ 313, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282545" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "ultrasound" ], "offsets": [ [ 336, 346 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220934" }, { "db_name": "UMLS", "db_id": "C0041618" }, { "db_name": "UMLS", "db_id": "C0041621" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "cataract" ], "offsets": [ [ 396, 404 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007388" } ] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 405, 412 ] 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DerOpthalmologe.90960648.eng.abstr	DerOpthalmologe.90960648.eng.abstr	[ { "id": "DerOpthalmologe.90960648.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The transplantation of retinal pigment epithelial cells ( RPE ) in patients with age-related macular degeneration is discussed as a future therapy . A cornea bank can serve as a source for cells that can be isolated , cultivated , HLA-typed and cryopreserved for subsequent tissue-compatible transplantation ." ], "offsets": [ [ 0, 322 ] ] } ]	[ { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "transplantation" ], "offsets": [ [ 17, 32 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "retinal" ], "offsets": [ [ 36, 43 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "pigment" ], "offsets": [ [ 44, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031916" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 63, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 80, 88 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "future" ], "offsets": [ [ 145, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016884" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 152, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "retinal pigment" ], "offsets": [ [ 36, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035323" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "epithelial cells" ], "offsets": [ [ 52, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014597" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "macular degeneration" ], "offsets": [ [ 106, 126 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024437" }, { "db_name": "UMLS", "db_id": "C0242383" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "cornea" ], "offsets": [ [ 164, 170 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010031" }, { "db_name": "UMLS", "db_id": "C0010034" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 202, 207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "tissue-compatible" ], "offsets": [ [ 287, 304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "transplantation" ], "offsets": [ [ 305, 320 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960648.eng.abstr-s1-r1-t6.1-t10.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960648.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960648.eng.abstr-s1-t10", "normalized": [] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-r2-t3.1-t10.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960648.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960648.eng.abstr-s1-t10", "normalized": [] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-r3-t6.1-t3.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960648.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960648.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960648.eng.abstr-s1-r4-t4.1-t1.3", "type": "produces", "arg1_id": "DerOpthalmologe.90960648.eng.abstr-s2-t4", "arg2_id": 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DerOpthalmologe.90960653.eng.abstr	DerOpthalmologe.90960653.eng.abstr	[ { "id": "DerOpthalmologe.90960653.eng.abstr-passage-0", "type": "abstract", "text": [ "In incurable glaucoma the implantation of traditional drainage systems ( such as the Molteno implant ) usually leads to extreme hypotension in the eye in the first postoperative period . The Ahmed Glaucoma Valve presents an alternative method to avoid this problem ." ], "offsets": [ [ 0, 266 ] ] } ]	[ { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 13, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "implantation" ], "offsets": [ [ 26, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029976" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "drainage" ], "offsets": [ [ 54, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013103" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "hypotension" ], "offsets": [ [ 128, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020649" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "eye" ], "offsets": [ [ 147, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 164, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 178, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "Molteno implant" ], "offsets": [ [ 85, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0181899" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "postoperative period" ], "offsets": [ [ 164, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s2-t1", "type": "umlsterm", 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DerOpthalmologe.90960658.eng.abstr	DerOpthalmologe.90960658.eng.abstr	[ { "id": "DerOpthalmologe.90960658.eng.abstr-passage-0", "type": "abstract", "text": [ "Dacryocystorhinostomy is still the standard procedure complete stenosis of the nasolacrimal duct . New methods try to preserve the natural lacrimal pathway . Song implanted in 1995 a nasolacrimal polyurethane stent through the nasolacrimal duct . The results and complications of this new method are described in this prospective study ." ], "offsets": [ [ 0, 337 ] ] } ]	[ { "id": "DerOpthalmologe.90960658.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Dacryocystorhinostomy" ], "offsets": [ [ 0, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010931" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "standard" ], "offsets": [ [ 35, 43 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038137" }, { "db_name": "UMLS", "db_id": "C0175675" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 44, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "stenosis" ], "offsets": [ [ 63, 71 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009814" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "nasolacrimal duct" ], "offsets": [ [ 79, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027437" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 103, 110 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "polyurethane" ], "offsets": [ [ 196, 208 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032616" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "stent" ], "offsets": [ [ 209, 214 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038257" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "nasolacrimal duct" ], "offsets": [ [ 227, 244 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027437" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 263, 276 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 289, 295 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "prospective study" ], "offsets": [ [ 318, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033522" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r1-t2.1-t1.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r2-t2.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r3-t5.1-t2.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r4-t2.2-t1.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r5-t5.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r6-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r7-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s1-r8-t3.1-t1.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t3", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s3-r1-t3.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t3", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-r1-t2.2-t1.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-r2-t2.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960658.eng.abstr-s4-r3-t1.1-t2.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960658.eng.abstr-s4-t1", "arg2_id": "DerOpthalmologe.90960658.eng.abstr-s4-t2", "normalized": [] } ]
DerOpthalmologe.90960663.eng.abstr	DerOpthalmologe.90960663.eng.abstr	[ { "id": "DerOpthalmologe.90960663.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Most germs causing postoperative endophthalmitis derive from the conjunctival bacterial normal flora . Postoperative endophthalmitis is often induced by staphylococcal germs . The application of polyvidone-iodine solution to the conjunctiva is one possibility to reduce potential endophthalmitis-causing bacteria . The aim of this study was to evaluate the effectiveness of 1 % polyvidone-iodine solution concerning the reduction of colonization with staphylococci in the course of intraocular surgery . This is to evaluate the effectiveness of 1 % polyvidone-iodine solution concerning coagulase-negative and positive staphylococci ." ], "offsets": [ [ 0, 647 ] ] } ]	[ { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 32, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "endophthalmitis" ], "offsets": [ [ 46, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014236" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "bacterial" ], "offsets": [ [ 91, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0521009" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Postoperative" ], "offsets": [ [ 116, 129 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "endophthalmitis" ], "offsets": [ [ 130, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014236" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 226, 234 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "conjunctiva" ], "offsets": [ [ 242, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009758" }, { "db_name": "UMLS", "db_id": "C0009759" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "bacteria" ], "offsets": [ [ 317, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004611" }, { "db_name": "UMLS", "db_id": "C0521009" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 332, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 409, 417 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "staphylococci" ], "offsets": [ [ 464, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038170" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 507, 514 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 580, 588 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "coagulase-negative" ], "offsets": [ [ 600, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009118" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "staphylococci" ], "offsets": [ [ 632, 645 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038170" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960663.eng.abstr-s3-r1-t2.1-t2.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-r2-t2.1-t3.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-r3-t2.2-t3.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-r4-t3.1-t2.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-r5-t1.1-t2.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-r1-t1.1-t4.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-r2-t3.1-t4.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-r3-t1.1-t3.1", "type": "indicates", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-r4-t3.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-r1-t1.1-t2.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-r2-t2.1-t1.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-r3-t3.1-t2.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "arg2_id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "normalized": [] } ]
DerOpthalmologe.90960668.eng.abstr	DerOpthalmologe.90960668.eng.abstr	[ { "id": "DerOpthalmologe.90960668.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Retinal laser coagulation ( LC ) of extrafoveal subretinal neovascularization ( SRN ) due to age-related macular degeneration ( AMD ) is the only sure therapy . Diagnostics , therapy and follow-up are presented in a case report ." ], "offsets": [ [ 0, 244 ] ] } ]	[ { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Retinal" ], "offsets": [ [ 15, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 23, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "coagulation" ], "offsets": [ [ 29, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "neovascularization" ], "offsets": [ [ 74, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027686" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 166, 173 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "laser coagulation" ], "offsets": [ [ 23, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086524" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "macular degeneration" ], "offsets": [ [ 120, 140 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024437" }, { "db_name": "UMLS", "db_id": "C0242383" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Diagnostics" ], "offsets": [ [ 176, 187 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 190, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "case report" ], "offsets": [ [ 231, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007320" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960668.eng.abstr-s1-r1-t2.1-t4.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960668.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960668.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-r2-t5.1-t7.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960668.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-r3-t7.1-t4.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960668.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-r4-t7.2-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "arg2_id": 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DerOpthalmologe.90960673.eng.abstr	DerOpthalmologe.90960673.eng.abstr	[ { "id": "DerOpthalmologe.90960673.eng.abstr-passage-0", "type": "abstract", "text": [ "Persistent defects of the ocular surface remain a therapeutic challenge , which often requires surgical intervention . Recently , transplantation of human amniotic membrane has been suggested for reconstruction of the corneal surface . We describe two techniques using cryo-preserved amniotic membrane . Transplantation of several layers of amniotic membrane can successfully restore deep corneal ulcers associated with persistent epithelial defects . When such defects are not associated with stromal ulcers , they might benefit from amniotic membrane grafts sutured to cover the entire corneal surface . Both methods may serve as valuable tools for ocular surface reconstruction , especially in the context of impaired epithelial function ." ], "offsets": [ [ 0, 742 ] ] } ]	[ { "id": "DerOpthalmologe.90960673.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 11, 18 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 50, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 95, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "transplantation" ], "offsets": [ [ 130, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 149, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 164, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "amniotic membrane" ], "offsets": [ [ 155, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002630" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 252, 262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 293, 301 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "amniotic membrane" ], "offsets": [ [ 284, 301 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002630" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Transplantation" ], "offsets": [ [ 304, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 350, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "ulcers" ], "offsets": [ [ 397, 403 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041582" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 442, 449 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "amniotic membrane" ], "offsets": [ [ 341, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002630" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "corneal ulcers" ], "offsets": [ [ 389, 403 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010043" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 462, 469 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "ulcers" ], "offsets": [ [ 502, 508 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041582" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 544, 552 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "amniotic membrane" ], "offsets": [ [ 535, 552 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002630" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 611, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 732, 740 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960673.eng.abstr-s2-r1-t4.1-t2.1", "type": "part_of", "arg1_id": "DerOpthalmologe.90960673.eng.abstr-s5-t4", "arg2_id": "DerOpthalmologe.90960673.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s2-r2-t1.3-t1.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960673.eng.abstr-s4-t1", "arg2_id": 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DerOpthalmologe.90960698.eng.abstr	DerOpthalmologe.90960698.eng.abstr	[ { "id": "DerOpthalmologe.90960698.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Leber's hereditary optic neuropathy is associated with point mutations in the mitochondrial DNA ( mtDNA ) that appear to be pathogenetic for this disease . These mutations affect nucleotide positions 3460 , 11778 and 14484. Does the clinical course of LHON differ between men , women and children ?" ], "offsets": [ [ 0, 311 ] ] } ]	[ { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "optic" ], "offsets": [ [ 32, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029144" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 74, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "DNA" ], "offsets": [ [ 105, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012854" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "mtDNA" ], "offsets": [ [ 111, 116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012929" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 159, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "optic neuropathy" ], "offsets": [ [ 32, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029132" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "point mutations" ], "offsets": [ [ 68, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162735" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "mitochondrial DNA" ], "offsets": [ [ 91, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012929" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 175, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "nucleotide" ], "offsets": [ [ 192, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028630" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "men" ], "offsets": [ [ 285, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025266" }, { "db_name": "UMLS", "db_id": "C0024554" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "women" ], "offsets": [ [ 291, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 301, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960698.eng.abstr-s1-r1-t2.1-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960698.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960698.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-r2-t5.1-t2.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960698.eng.abstr-s2-t5", "arg2_id": 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We present a placebo-controlled study in which we focused on the short and long-term effects of topical dipivefrine 0.1 % on the microcirculation of the retina and optic nerve head ." ], "offsets": [ [ 0, 475 ] ] } ]	[ { "id": "DerOpthalmologe.90960706.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "antiglaucomatous" ], "offsets": [ [ 22, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003209" }, { "db_name": "UMLS", "db_id": "C0003204" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "drugs" ], "offsets": [ [ 39, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 59, 64 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Blood" ], "offsets": [ [ 72, 77 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 90, 98 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "uvea" ], "offsets": [ [ 99, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042160" }, { "db_name": "UMLS", "db_id": "C0042161" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 124, 132 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "medication" ], "offsets": [ [ 133, 143 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 170, 180 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "measurement" ], "offsets": [ [ 187, 198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242485" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "microcirculation" ], "offsets": [ [ 202, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025962" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 226, 235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 255, 263 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "medication" ], "offsets": [ [ 264, 274 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "dipivefrine" ], "offsets": [ [ 397, 408 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0058415" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "microcirculation" ], "offsets": [ [ 422, 438 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025962" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "retina" ], "offsets": [ [ 446, 452 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035298" }, { "db_name": "UMLS", "db_id": "C0035309" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "optic" ], "offsets": [ [ 457, 462 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029144" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "nerve" ], "offsets": [ [ 463, 468 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027769" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 469, 473 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "long-term effects" ], "offsets": [ [ 368, 385 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023983" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "optic nerve" ], "offsets": [ [ 457, 468 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0346323" }, { "db_name": "UMLS", "db_id": "C0029130" }, { "db_name": "UMLS", "db_id": "C0029132" } ] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "optic nerve head" ], "offsets": [ [ 457, 473 ] ], "normalized": [ { 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"DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r72-t5.1-t3.1", "type": "adjacent_to", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r73-t3.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r74-t1.1-t8.3", "type": "diagnoses", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r75-t8.3-t7.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r76-t7.1-t5.1", "type": "adjacent_to", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r77-t7.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r78-t3.2-t7.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r79-t7.1-t1.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r80-t9.1-t7.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r81-t1.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r82-t1.1-t5.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r84-t8.3-t7.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r85-t3.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r87-t3.2-t7.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r88-t5.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r89-t1.1-t8.3", "type": "affects", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r90-t9.1-t5.1", "type": "adjacent_to", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r91-t9.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r92-t5.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r93-t1.1-t3.2", "type": "diagnoses", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "normalized": [] } ]
DerOpthalmologe.90960711.eng.abstr	DerOpthalmologe.90960711.eng.abstr	[ { "id": "DerOpthalmologe.90960711.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Data on mesopic vision after LASIK are not available to date . We therefore evaluated mesopic vision in myopic eyes before and after LASIK ." ], "offsets": [ [ 0, 153 ] ] } ]	[ { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 29, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "LASIK" ], "offsets": [ [ 42, 47 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0752094" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "date" ], "offsets": [ [ 69, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011008" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 107, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 124, 128 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "LASIK" ], "offsets": [ [ 146, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0752094" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960711.eng.abstr-s1-r1-t1.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-r2-t2.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-r3-t3.1-t1.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r1-t1.1-t2.2", "type": "result_of", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r2-t1.1-t2.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r3-t2.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r7-t1.1-t2.3", "type": "affects", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r9-t2.2-t1.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-r11-t2.2-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "normalized": [] } ]
DerOpthalmologe.90960724.eng.abstr	DerOpthalmologe.90960724.eng.abstr	[ { "id": "DerOpthalmologe.90960724.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Orbitotomies have special place in ophthalmic surgery because of the anatomical structures involved and the variety of perioperative problems . We performed a retrospective analysis of orbitotomies carried out in our department in order to give us some more detailed information about the frequency and extent of the various intra- and postoperative problems of orbital surgery ." ], "offsets": [ [ 0, 392 ] ] } ]	[ { "id": "DerOpthalmologe.90960724.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 59, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anatomical" ], "offsets": [ [ 82, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "retrospective" ], "offsets": [ [ 172, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 186, 194 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 302, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 349, 362 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 383, 390 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960724.eng.abstr-s1-r1-t1.2-t1.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s1-r2-t2.1-t1.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r1-t2.1-t3.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r3-t2.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r4-t2.1-t1.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r5-t2.1-t5.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r6-t3.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r7-t1.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] } ]
DerOpthalmologe.90960728.eng.abstr	DerOpthalmologe.90960728.eng.abstr	[ { "id": "DerOpthalmologe.90960728.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : Retrospective study concerning the value of conjunctival biopsy in the diagnosis of sarcoidosis ." ], "offsets": [ [ 0, 107 ] ] } ]	[ { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Retrospective" ], "offsets": [ [ 10, 23 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "value" ], "offsets": [ [ 45, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042295" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "biopsy" ], "offsets": [ [ 67, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 81, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "sarcoidosis" ], "offsets": [ [ 94, 105 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036202" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "Retrospective study" ], "offsets": [ [ 10, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960728.eng.abstr-s1-r1-t2.1-t4.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960728.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960728.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-r2-t4.2-t2.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960728.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960728.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-r3-t2.1-t3.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960728.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960728.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-r5-t4.2-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960728.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960728.eng.abstr-s1-t3", "normalized": [] } ]
DerOpthalmologe.90960731.eng.abstr	DerOpthalmologe.90960731.eng.abstr	[ { "id": "DerOpthalmologe.90960731.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Rarely , an additional Brown's syndrome develops spontaneously in cases of posttraumatic bilateral superior oblique palsy . Surgical measures are controversial and problematic ." ], "offsets": [ [ 0, 190 ] ] } ]	[ { "id": "DerOpthalmologe.90960731.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Brown's" ], "offsets": [ [ 36, 43 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0605770" } ] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 44, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "palsy" ], "offsets": [ [ 129, 134 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030440" } ] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "superior oblique palsy" ], "offsets": [ [ 112, 134 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0152176" } ] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Surgical" ], "offsets": [ [ 137, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "measures" ], "offsets": [ [ 146, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079809" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960731.eng.abstr-s1-r1-t1.1-t4.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960731.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960731.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960731.eng.abstr-s1-r2-t1.1-t3.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960731.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960731.eng.abstr-s1-t3", "normalized": [] } ]
DerOpthalmologe.90960736.eng.abstr	DerOpthalmologe.90960736.eng.abstr	[ { "id": "DerOpthalmologe.90960736.eng.abstr-passage-0", "type": "abstract", "text": [ "There is no generally accepted therapy for patients with central retinal vein occlusion . Only few of the therapeutic strategies in use demonstrated their effectiveness in studies with large patient populations , others have the disadvantage of unacceptable side effects . The aim of the immediate therapy is the improvement of blood perfusion . Prognostically relevant factors like the activity of components of the blood coagulation system , rheology characteristics and predisposing vascular disease risk factors have to be considered . A risk adapted management includes the immediate anticoagulation with heparin . Haemodilution , fibrinolytic therapy and hyperbaric oxygen therapy represent other therapeutic strategies . The efficacy of new promising therapies has to be thoroughly evaluated in studies with large stratified patient populations ." ], "offsets": [ [ 0, 853 ] ] } ]	[ { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 31, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 43, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "retinal" ], "offsets": [ [ 65, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "vein" ], "offsets": [ [ 73, 77 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042449" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "retinal vein" ], "offsets": [ [ 65, 77 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035327" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "retinal vein occlusion" ], "offsets": [ [ 65, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035328" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 106, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 132, 135 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 191, 198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "populations" ], "offsets": [ [ 199, 210 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032659" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "side effects" ], "offsets": [ [ 258, 270 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001688" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 277, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 298, 305 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 328, 333 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "perfusion" ], "offsets": [ [ 334, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031001" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 417, 422 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "coagulation" ], "offsets": [ [ 423, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "rheology" ], "offsets": [ [ 444, 452 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035423" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 495, 502 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 503, 507 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "blood coagulation" ], "offsets": [ [ 417, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005778" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "vascular disease" ], "offsets": [ [ 486, 502 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042373" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "risk factors" ], "offsets": [ [ 503, 515 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035648" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 542, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "anticoagulation" ], "offsets": [ [ 589, 604 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003209" }, { "db_name": "UMLS", "db_id": "C0003204" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "anticoagulation" ], "offsets": [ [ 589, 604 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "heparin" ], "offsets": [ [ 610, 617 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019134" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Haemodilution" ], "offsets": [ [ 620, 633 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019009" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 649, 656 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "oxygen" ], "offsets": [ [ 672, 678 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030054" }, { "db_name": "UMLS", "db_id": "C0184633" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 679, 686 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 703, 714 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "fibrinolytic therapy" ], "offsets": [ [ 636, 656 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040044" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s6-t7", "type": "umlsterm", "text": [ "oxygen therapy" 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DerOpthalmologe.90960741.eng.abstr	DerOpthalmologe.90960741.eng.abstr	[ { "id": "DerOpthalmologe.90960741.eng.abstr-passage-0", "type": "abstract", "text": [ "Problem : The Internet is not structured hierarchically and therefore it distinguishes from today's common knowledge sources . The rapidly growing number of medical websites offers comprehensive but not easy to find information resources and continuing education opportunities for ophthalmologists ." ], "offsets": [ [ 0, 299 ] ] } ]	[ { "id": "DerOpthalmologe.90960741.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Internet" ], "offsets": [ [ 14, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282111" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "today's" ], "offsets": [ [ 92, 99 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0605770" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 107, 116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "knowledge sources" ], "offsets": [ [ 107, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022757" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "resources" ], "offsets": [ [ 228, 237 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035201" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "education" ], "offsets": [ [ 253, 262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013621" }, { "db_name": "UMLS", "db_id": "C0013622" } ] }, { "id": "DerOpthalmologe.90960741.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "continuing education" ], "offsets": [ [ 242, 262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013626" } ] } ]	[]	[]	[]
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The fact that so far there are no reports about this specific disease in the German literature signifies a lack in the diagnosis of thromboembolic diseases ." ], "offsets": [ [ 0, 591 ] ] } ]	[ { "id": "DerOpthalmologe.90960777.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Objective" ], "offsets": [ [ 0, 9 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018017" } ] }, { "id": "DerOpthalmologe.90960777.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anticoagulatory" ], "offsets": [ [ 35, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003209" }, { "db_name": "UMLS", "db_id": "C0003204" } ] }, { "id": "DerOpthalmologe.90960777.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "protein" ], "offsets": [ [ 71, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOpthalmologe.90960777.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "APC" ], "offsets": [ [ 83, 86 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003315" }, { "db_name": 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DerOpthalmologe.90960786.eng.abstr	DerOpthalmologe.90960786.eng.abstr	[ { "id": "DerOpthalmologe.90960786.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age ." ], "offsets": [ [ 0, 385 ] ] } ]	[ { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "cryotherapy" ], "offsets": [ [ 59, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010412" }, { "db_name": "UMLS", "db_id": "C0010408" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "morphological" ], "offsets": [ [ 113, 126 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543482" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 153, 157 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "retinopathy" ], "offsets": [ [ 173, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035309" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "prematurity" ], "offsets": [ [ 188, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0270079" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "retinopathy of prematurity" ], "offsets": [ [ 173, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035344" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 244, 248 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "cryocoagulation" ], "offsets": [ [ 279, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "hospital" ], "offsets": [ [ 302, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019994" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "age" ], "offsets": [ [ 380, 383 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "visual acuity" ], "offsets": [ [ 224, 237 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042812" } ] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "gestational age" ], "offsets": [ [ 368, 383 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017504" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960786.eng.abstr-s1-r2-t3.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960786.eng.abstr-s1-t3", "arg2_id": 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DerOpthalmologe.90960792.eng.abstr	DerOpthalmologe.90960792.eng.abstr	[ { "id": "DerOpthalmologe.90960792.eng.abstr-passage-0", "type": "abstract", "text": [ "Efficacy and complications of intravitreally injected tissue plasminogen activator ( rt-PA ) and sulfahexafluoride gas ( SF6) in submacular hemorrhage are demonstrated ." ], "offsets": [ [ 0, 169 ] ] } ]	[ { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 13, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 54, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "plasminogen" ], "offsets": [ [ 61, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032140" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "gas" ], "offsets": [ [ 115, 118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017110" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "hemorrhage" ], "offsets": [ [ 140, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019080" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "plasminogen activator" ], "offsets": [ [ 61, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032144" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "tissue plasminogen activator" ], "offsets": [ [ 54, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032143" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r1-t3.1-t4.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "normalized": [] }, { "id": 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"DerOpthalmologe.90960792.eng.abstr-s1-r25-t5.1-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r26-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r27-t4.1-t3.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r28-t7.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r29-t3.1-t1.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", 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"DerOpthalmologe.90960792.eng.abstr-s1-r34-t3.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r35-t3.1-t6.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r36-t4.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "normalized": [] } ]
DerOpthalmologe.90960797.eng.abstr	DerOpthalmologe.90960797.eng.abstr	[ { "id": "DerOpthalmologe.90960797.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Confocal indocyanin green angiography ( ICGA ) offers detailed two-dimensional imaging of choroidal pathologies . However , the spatial extension of lesions is not reproduced . We developed a novel method for three-dimensional documentation of choroidal vascular abnormalities ." ], "offsets": [ [ 0, 291 ] ] } ]	[ { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "angiography" ], "offsets": [ [ 39, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002978" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "imaging" ], "offsets": [ [ 92, 99 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "pathologies" ], "offsets": [ [ 113, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 211, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 240, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "abnormalities" ], "offsets": [ [ 276, 289 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0000769" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960797.eng.abstr-s1-r1-t1.1-t3.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-r2-t2.1-t3.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-r1-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-r2-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "normalized": [] } ]
DerOpthalmologe.90960813.eng.abstr	DerOpthalmologe.90960813.eng.abstr	[ { "id": "DerOpthalmologe.90960813.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : To assess patient reliability and compliance , most perimeters check for false-positive and -negative answers . In this study the results of catch trials were obtained with video campimetry with respect to age-related changes and differences for tests using increment and decrement stimuli ." ], "offsets": [ [ 0, 301 ] ] } ]	[ { "id": "DerOpthalmologe.90960813.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 20, 27 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "compliance" ], "offsets": [ [ 44, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030680" }, { "db_name": "UMLS", "db_id": "C0009563" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "campimetry" ], "offsets": [ [ 189, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006810" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tests" ], "offsets": [ [ 256, 261 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960813.eng.abstr-s1-r1-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s1-r2-t1.1-t2.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-r1-t1.1-t2.1", "type": "analyzes", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "normalized": [] } ]
DerOpthalmologe.90960822.eng.abstr	DerOpthalmologe.90960822.eng.abstr	[ { "id": "DerOpthalmologe.90960822.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The aim of this study was to analyze risk factors , therapeutic strategies , and functional and anatomic results of eyes with severe suprachoroidal hemorrhage ." ], "offsets": [ [ 0, 173 ] ] } ]	[ { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 17, 20 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 50, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 65, 76 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "anatomic" ], "offsets": [ [ 109, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 129, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "hemorrhage" ], "offsets": [ [ 161, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019080" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "risk factors" ], "offsets": [ [ 50, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035648" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r1-t5.2-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r2-t1.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r3-t1.1-t5.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r4-t4.1-t3.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r6-t3.1-t5.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r8-t1.1-t5.2", "type": "indicates", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r9-t1.1-t4.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r10-t5.2-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r11-t1.1-t3.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r12-t4.1-t5.3", "type": "part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r13-t4.1-t5.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r14-t4.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r15-t7.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r16-t4.1-t5.2", "type": "part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] } ]
DerOpthalmologe.90960829.eng.abstr	DerOpthalmologe.90960829.eng.abstr	[ { "id": "DerOpthalmologe.90960829.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The purpose of this study was to evaluate the course of CMV retinitis after initiation of highly active antiretroviral therapy ( HAART ) and discontinuation of systemic anti-CMV maintenance therapy ." ], "offsets": [ [ 0, 212 ] ] } ]	[ { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "CMV" ], "offsets": [ [ 69, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010825" }, { "db_name": "UMLS", "db_id": "C0285131" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "retinitis" ], "offsets": [ [ 73, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035333" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 132, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "HAART" ], "offsets": [ [ 142, 147 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0887947" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "maintenance" ], "offsets": [ [ 191, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024501" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 203, 210 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "CMV retinitis" ], "offsets": [ [ 69, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206178" } ] } ]	[]	[]	[ { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r1-t6.1-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r2-t1.2-t6.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r4-t1.2-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r5-t5.1-t6.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r6-t6.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r7-t6.1-t1.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r8-t1.2-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r9-t1.1-t6.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r10-t5.1-t1.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-r11-t6.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "normalized": [] } ]
DerOrthopaede.00290002.eng.abstr	DerOrthopaede.00290002.eng.abstr	[ { "id": "DerOrthopaede.00290002.eng.abstr-passage-0", "type": "abstract", "text": [ "The percutaneous epiphysiodesis is recommended as a save and reliable technique . We have performed 21 distal femoral , 17 proximal tibial and 3 proximal fibular percutaneous epiphyseodeses on 25 patients . On 11 patients the epiphysiodesis was caused by an average leg length discrepancy of 2,7 cm ( 1-4 cm ) . 13 patients had angular deformity near the knee joint in frontal plane ( 6 valgus and 7 varus deformities ) . One patient suffered from a combined deformity with 3,5 cm shortened leg and varus deviation of 10 ° . The average deformity angle of the knee was 7,4 ° ( 4 °-16 ° ) . 9 patients have reached maturity . On 3 patients the deformity could be corrected incompetely with residual deformity of 3 ° , 4 ° and 6 ° as a direct result of late referral . On 1 patient an imminent over-correction could be avoided by hemiepiphysiodesis of the residual epiphysis . Till the present follow up the other patients have been corrected as calculated preoperatively . No complications like epiphysiolysis , infection , stiff knee or angular deformities occurred . We prefer the percutaneous epiphysiodesis as a save and minimal invasiv technique instead of the open Phemister-technique to tread leg length discrepancy and angular deformities of the knee in frontal plane ." ], "offsets": [ [ 0, 1276 ] ] } ]	[ { "id": "DerOrthopaede.00290002.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 70, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 196, 204 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 213, 221 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "leg" ], "offsets": [ [ 266, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023216" } ] }, { "id": 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DerOrthopaede.00290009.eng.abstr	DerOrthopaede.00290009.eng.abstr	[ { "id": "DerOrthopaede.00290009.eng.abstr-passage-0", "type": "abstract", "text": [ "Skeletal deformities do occur after conservative or operative fracture treatment , as a consequence of congenital growth disturbance and as sequlae after posttraumatic and haematogenous osteomyelitis . In postinfectious deformities the course of the bone and soft tissue infection plays a decisive role when choosing the appropriate operative technique . Even in non active situations with a closed soft tissues envelope and no draining sinus persistence of germs within the bone has to be anticipated . The biological quality of the bone and the soft tissue envelope is often reduced because of local changes and as a result of multiple local revisions . Consequently wide areas of scar tissue and sclerotic bone are often encountered . The apex of the deformity is in most cases identical with the focus of the active or non active infection . The correction of the deformity at the apex can therefore only be accomplished if the infectious bone is also resected . If a correction is not possible at the apex of the deformity , translation at the osteotomy site is necessary to achieve a correct mechanical axis . The later rather complex operative procedure necessitates intensive preoperative planning and an extensive experience with deformity corrections by external fixators ." ], "offsets": [ [ 0, 1283 ] ] } ]	[ { "id": "DerOrthopaede.00290009.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 9, 20 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "fracture" ], "offsets": [ [ 62, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 71, 80 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "congenital" ], "offsets": [ [ 103, 113 ] ], "normalized": [ { 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] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 271, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "role" ], "offsets": [ [ 298, 302 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035820" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 343, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "soft tissue infection" ], "offsets": [ [ 259, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0149778" } ] }, { "id": "DerOrthopaede.00290009.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tissues" ], "offsets": [ [ 404, 411 ] ], "normalized": [ { "db_name": "UMLS", "db_id": 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DerOrthopaede.00290039.eng.abstr	DerOrthopaede.00290039.eng.abstr	[ { "id": "DerOrthopaede.00290039.eng.abstr-passage-0", "type": "abstract", "text": [ "The hexapod is a construction that has been subjected to a great deal of investigation in robotics for use in three-dimensional positioning . One use of it is for positioning of the cockpit in flight simulators . Application of the hexapod principle in the external fixator makes it possible to realize prescribed movements of bone fragments with a simple and stable design . The precise setting of the system requires software that has been developed and optimized for clinical use . Translations , axis corrections and rotations are possible individually and also in combinations for correction of complex deformities . The system has advantages , especially in the case of rotations around the longitudinal axis of the bone and in the realization of translation movements . Because the centres of rotation are taken into account by the mathematical calculations , the planning of corrections is simplified . The hexapod system is described , and its clinical application is presented with reference to case reports ." ], "offsets": [ [ 0, 1019 ] ] } ]	[ { "id": "DerOrthopaede.00290039.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "robotics" ], "offsets": [ [ 90, 98 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035785" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 103, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 146, 149 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "movements" ], "offsets": [ [ 314, 323 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026649" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 327, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "external fixator" ], "offsets": [ [ 257, 273 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079321" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "software" ], "offsets": [ [ 419, 427 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037585" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 479, 482 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Translations" ], "offsets": [ [ 485, 497 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040712" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "axis" ], "offsets": [ [ 500, 504 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004457" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "rotations" ], "offsets": [ [ 521, 530 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 608, 619 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "rotations" ], "offsets": [ [ 676, 685 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "axis" ], "offsets": [ [ 710, 714 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004457" } ] }, { "id": "DerOrthopaede.00290039.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 722, 726 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": 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DerOrthopaede.00290047.eng.abstr	DerOrthopaede.00290047.eng.abstr	[ { "id": "DerOrthopaede.00290047.eng.abstr-passage-0", "type": "abstract", "text": [ "The introduction of joints in unilateral fixators enables these for multiple deformity corrections . Lengthening and shortening is achieved by changing the length of the fixator telescope . Axial corrections are performed by additive or subtractive techniques using uniplanar joints or by angulation procedures . Translation is done by direct movements of the bone fragments or by metaphyseal \" double angulation \" . Derotation preferably is done as an acute procedure or in the \" ring part \" of a hybrid frame . Unilateral fixators are used to correct and temporarily stabilize until the correction is held by the nintramedullary nail ." ], "offsets": [ [ 0, 637 ] ] } ]	[ { "id": "DerOrthopaede.00290047.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "joints" ], "offsets": [ [ 20, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 77, 86 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 249, 259 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "joints" ], "offsets": [ [ 276, 282 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 300, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Translation" ], "offsets": [ [ 313, 324 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040712" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "direct" ], "offsets": [ [ 336, 342 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700157" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "movements" ], "offsets": [ [ 343, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026649" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 360, 364 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 459, 468 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "hybrid" ], "offsets": [ [ 498, 504 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020205" } ] }, { "id": "DerOrthopaede.00290047.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "nail" ], "offsets": [ [ 631, 635 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027342" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290047.eng.abstr-s1-r1-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290047.eng.abstr-s6-t1", "arg2_id": "DerOrthopaede.00290047.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290047.eng.abstr-s3-r1-t3.1-t1.1", "type": "measurement_of", "arg1_id": "DerOrthopaede.00290047.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290047.eng.abstr-s6-t1", "normalized": [] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-r1-t2.1-t4.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290047.eng.abstr-s5-t2", "arg2_id": "DerOrthopaede.00290047.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290047.eng.abstr-s4-r2-t4.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290047.eng.abstr-s4-t4", "arg2_id": "DerOrthopaede.00290047.eng.abstr-s5-t2", "normalized": [] } ]
DerOrthopaede.00290054.eng.abstr	DerOrthopaede.00290054.eng.abstr	[ { "id": "DerOrthopaede.00290054.eng.abstr-passage-0", "type": "abstract", "text": [ "Congenital tibial pseudarthrosis ( CTP ) remains one of the most challenging problems in paediatric orthopaedic surgery . With the abandonment of older grafting techniques in favor of vascularized fibular transplants or the Ilizarov method the final outcome has improved and made the prognosis for patients less cumbersome . Using the latter technique in 10 patients , a success rate of 90 % could be reached . Nevertheless , although solid healing occurs in most of the patients nowadays , this is often at the cost of multiple operations before a definite well united , equalized and normally aligned limb can be obtained ." ], "offsets": [ [ 0, 625 ] ] } ]	[ { "id": "DerOrthopaede.00290054.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Congenital" ], "offsets": [ [ 0, 10 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009678" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "pseudarthrosis" ], "offsets": [ [ 18, 32 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033785" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "CTP" ], "offsets": [ [ 35, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010734" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 112, 119 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "older" ], "offsets": [ [ 146, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "grafting" ], "offsets": [ [ 152, 160 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 161, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "transplants" ], "offsets": [ [ 205, 216 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 233, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "prognosis" ], "offsets": [ [ 284, 293 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033325" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 298, 306 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "Ilizarov method" ], "offsets": [ [ 224, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282514" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 342, 351 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 358, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 471, 479 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "cost" ], "offsets": [ [ 512, 516 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010186" }, { "db_name": "UMLS", "db_id": "C0010181" }, { "db_name": "UMLS", "db_id": "C0220812" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "operations" ], "offsets": [ [ 529, 539 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "limb" ], "offsets": [ [ 603, 607 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015385" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290054.eng.abstr-s1-r1-t1.1-t4.1", "type": "issue_in", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-r2-t3.1-t4.1", "type": "issue_in", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-r3-t3.1-t1.1", "type": "affects", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-r4-t1.1-t3.1", "type": "produces", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s1-r5-t4.2-t4.1", "type": "issue_in", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t4", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r1-t7.1-t2.2", "type": "uses", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r2-t2.2-t8.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t8", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r3-t7.1-t3.1", "type": "uses", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r4-t1.1-t5.2", "type": "isa", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r5-t7.1-t5.2", "type": "performs", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r6-t7.1-t4.2", "type": "uses", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r7-t4.2-t1.1", "type": "property_of", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t4", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r8-t2.2-t1.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r9-t2.2-t1.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r10-t8.1-t7.1", "type": "affects", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t8", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r11-t7.1-t1.1", "type": "performs", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r12-t7.1-t8.1", "type": "performs", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t8", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r13-t7.1-t5.2", "type": "uses", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r14-t8.1-t5.2", "type": "isa", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s2-t8", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s2-r15-t1.1-t7.1", "type": "affects", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s2-t7", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-r1-t3.2-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-r2-t1.1-t2.1", "type": "performs", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOrthopaede.00290054.eng.abstr-s4-r3-t2.1-t1.1", "type": "affects", "arg1_id": "DerOrthopaede.00290054.eng.abstr-s4-t2", "arg2_id": "DerOrthopaede.00290054.eng.abstr-s4-t1", "normalized": [] } ]
DerOrthopaede.00290058.eng.abstr	DerOrthopaede.00290058.eng.abstr	[ { "id": "DerOrthopaede.00290058.eng.abstr-passage-0", "type": "abstract", "text": [ "Nine patients with achondroplasia and one patient with Apert syndrome underwent the surgical lengthening of both humerus and simultaneous correction of both associated bone deformity . An unilateral external fixator was applied to the lateral aspect of the humerus with four half-pins and percutaneous predrilling osteotomy was performed at the apex of flexion deformity of the bone . During the waiting period before distraction , the flexion deformity of the distal humerus was corrected using an additional external fixator . Slow gradual distraction was subsequently carried out at a rate of 0.25 mm every 6 hours . The average lengthening was 8 cm ( range 7.5 to 9 cm ) , the overall treatment time 312 days ( range 192 to 406 days ) , and the average healing index 39.0 days/cm . The average correction of the elbow flexion deformity was 20 degrees . We believe this treatment is useful to improve the function of the arms and the activity of daily living for the patients with bilateral short humeri ." ], "offsets": [ [ 0, 1008 ] ] } ]	[ { "id": "DerOrthopaede.00290058.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 5, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "achondroplasia" ], "offsets": [ [ 19, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001080" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 42, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 61, 69 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t5", "type": 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DerOrthopaede.00290068.eng.abstr	DerOrthopaede.00290068.eng.abstr	[ { "id": "DerOrthopaede.00290068.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of this study was to compare the initial stiffness of two techniques for posterior interbody lumbar fusion ( PLIF ) by a finite element approach . Thus a finite element model of a human L3/4 spinal segment was generated . Stiffness of the intact model was tested under compression ( 600 N ) , torsion ( 25 Nm ) and shearing forces ( 250 N ) without preload . The results were compared to the stiffness following simulation of PLIF with two BAK-Cages and PLIF with two Harms-Cages and additional posterior screw-rod-osteosynthesis . PLIF with two BAK-Cages resulted in a loss of stiffness in compression , torsion and shearing . PLIF with two Harms-Cages and posterior osteosynthesis resulted in an increase of stiffness in compression , torsion and shearing ." ], "offsets": [ [ 0, 771 ] ] } ]	[ { "id": "DerOrthopaede.00290068.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 70, 80 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 85, 94 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "element" ], "offsets": [ [ 140, 147 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013879" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "element" ], "offsets": [ [ 173, 180 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013879" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 192, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "torsion" ], "offsets": [ [ 305, 312 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040480" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 507, 516 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "torsion" ], "offsets": [ [ 617, 624 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040480" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 670, 679 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290068.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "torsion" ], "offsets": [ [ 749, 756 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040480" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290068.eng.abstr-s6-r1-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290068.eng.abstr-s6-t1", "arg2_id": "DerOrthopaede.00290068.eng.abstr-s6-t2", "normalized": [] } ]
DerOrthopaede.00290080.eng.abstr	DerOrthopaede.00290080.eng.abstr	[ { "id": "DerOrthopaede.00290080.eng.abstr-passage-0", "type": "abstract", "text": [ "As all living cell systems , human chondrocytes are provided with a membrane potential . For its origin the existence of ion channels at the cell membrane is an essential prerequisite . In non-human chondrocytes , different ion channels could already be identified . A connection between the potassium channel activity and the proliferation has been detected in different human cell systems . Whereas , the proof of a connection between ion channel activity of human chondrocytes and the proliferation has yet to be established . In this study the concentration-dependent influence of the ion channel modulators tetraethylammonium ( TEA ) , 4-amino-pyridin ( 4-AP ) , 4 ' , 4 ' diisothiocyanato-stilbene-2,2 ' disulfonic acid ( DIDS ) , 4-acetamido-4 ' isothiocyano-2,2 ' disulfonic acid stilbene ( SITS ) and verapamil on the membrane potential and the proliferation of human chondrocytes was investigated using flow cytometry . The results show an effect of the used ion channel modulators causing a change of the membrane potential of human chondrocytes . The decrease of the membrane potential by 18 % was measured with 0.25 mmol/l verapamil meaning the maximal measurable effect compared with a control group . When measuring DNA distribution , it became apparent that the human chondrocytes are diploid cells with a very low proliferation tendency . These results allow the conclusion of an influence of ion channel modulators on chondrocyte proliferation ." ], "offsets": [ [ 0, 1463 ] ] } ]	[ { "id": "DerOrthopaede.00290080.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 14, 18 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 29, 34 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 35, 47 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 68, 76 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "membrane potential" ], "offsets": [ [ 68, 86 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025251" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "origin" ], "offsets": [ [ 97, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079946" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "ion" ], "offsets": [ [ 121, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 141, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 146, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "ion channels" ], "offsets": [ [ 121, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022009" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "the cell" ], "offsets": [ [ 137, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "cell membrane" ], "offsets": [ [ 141, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007603" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "non-human" ], "offsets": [ [ 189, 198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 199, 211 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "ion" ], "offsets": [ [ 224, 227 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "ion channels" ], "offsets": [ [ 224, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022009" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "potassium" ], "offsets": [ [ 292, 301 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032821" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 372, 377 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 378, 382 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "potassium channel" ], "offsets": [ [ 292, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032824" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "ion" ], "offsets": [ [ 437, 440 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 461, 466 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 467, 479 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "ion channel" ], "offsets": [ [ 437, 448 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022009" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "concentration-dependent" ], "offsets": [ [ 548, 571 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086045" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "ion" ], "offsets": [ [ 589, 592 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "tetraethylammonium" ], "offsets": [ [ 612, 630 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076252" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "TEA" ], "offsets": [ [ 633, 636 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039400" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "acid" ], "offsets": [ [ 721, 725 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "DIDS" ], "offsets": [ [ 728, 732 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0057911" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t7", "type": "umlsterm", "text": [ "acid" ], "offsets": [ [ 783, 787 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t8", "type": "umlsterm", "text": [ "stilbene" ], "offsets": [ [ 788, 796 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038333" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t9", "type": "umlsterm", "text": [ "verapamil" ], "offsets": [ [ 810, 819 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042523" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t10", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 827, 835 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t11", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 871, 876 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t12", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 877, 889 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t13", "type": "umlsterm", "text": [ "ion channel" ], "offsets": [ [ 589, 600 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022009" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t14", "type": "umlsterm", "text": [ "membrane potential" ], "offsets": [ [ 827, 845 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025251" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s6-t15", "type": "umlsterm", "text": [ "flow cytometry" ], "offsets": [ [ 913, 927 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016263" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "ion" ], "offsets": [ [ 969, 972 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 1016, 1024 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 1038, 1043 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 1044, 1056 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "ion channel" ], "offsets": [ [ 969, 980 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022009" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s7-t6", "type": "umlsterm", "text": [ "membrane potential" ], "offsets": [ [ 1016, 1034 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025251" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "membrane" ], "offsets": [ [ 1079, 1087 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "verapamil" ], "offsets": [ [ 1136, 1145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042523" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 1200, 1207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "membrane potential" ], "offsets": [ [ 1079, 1097 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025251" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 1200, 1213 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "DNA" ], "offsets": [ [ 1231, 1234 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012854" } ] }, { "id": "DerOrthopaede.00290080.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "distribution" ], "offsets": [ [ 1235, 1247 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0520511" } ] }, { "id": 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DerOrthopaede.00290085.eng.abstr	DerOrthopaede.00290085.eng.abstr	[ { "id": "DerOrthopaede.00290085.eng.abstr-passage-0", "type": "abstract", "text": [ "The cell activity of human bone derived cell cultures was studied after mechanical stimulation by cyclic strain at a magnitude occurring in physiologically loaded bone tissue . Monolayers of subconfluently grown human bone derived cells were stretched in rectangular silicone dishes with cyclic uniaxial movement along their longitudinal axes . Strain was applied over two days for 30 min per day with a frequency of 1 Hz and a strain magnitude of 1000 µstrain. Cyclic stretching of the cells resulted in an increased proliferation ( 10-48 % ) and carboxyterminal collagen type I propeptide release ( 7-49 % ) of human cancellous bone derived osteoblasts while alkaline phosphatase activity and osteocalcin release were significantly reduced by 9-25 % and 5-32 % respectively . These results demonstrate that cyclic strain at physiologic magnitude leads to an increase of osteoblast activities related to matrix production while those activities which are characteristic for the differentiated osteoblast and relevant for matrix mineralization are decreased ." ], "offsets": [ [ 0, 1059 ] ] } ]	[ { "id": "DerOrthopaede.00290085.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 4, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 21, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 27, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 40, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "cultures" ], "offsets": [ [ 45, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220814" }, { "db_name": "UMLS", "db_id": "C0010453" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "strain" ], "offsets": [ [ 105, 111 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080194" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 163, 167 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 168, 174 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "The cell" ], "offsets": [ [ 0, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "cell cultures" ], "offsets": [ [ 40, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007585" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 212, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 218, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 231, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "silicone" ], "offsets": [ [ 267, 275 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037114" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "movement" ], "offsets": [ [ 304, 312 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026649" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "axes" ], "offsets": [ [ 338, 342 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004457" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Strain" ], "offsets": [ [ 345, 351 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080194" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 404, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "strain" ], "offsets": [ [ 428, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080194" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 487, 492 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 564, 572 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "release" ], "offsets": [ [ 591, 598 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 613, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 630, 634 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "osteoblasts" ], "offsets": [ [ 643, 654 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029418" } ] }, { 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DerOrthopaede.00290100.eng.abstr	DerOrthopaede.00290100.eng.abstr	[ { "id": "DerOrthopaede.00290100.eng.abstr-passage-0", "type": "abstract", "text": [ "Successful and cartilage-specific cultivation of chondrocytes requires a stable phenotype during the in vitro culture period . This is based on a differentiated extracellular matrix synthesis . The alginate system as a three-dimensional support is a useful system to culture chondrocytes and to analyze the biochemical processes in this system . Talar cartilage from the talocrural joints of 40 different donors were obtained through the Regional Organ Bank of Illinois within 24 hours of death . In 65 % of the tissues the cartilage was classified as being undamaged . In these studies we were interested in the results of short-term culture over 14 days . Cell proliferation , total collagen content and total proteoglycan content were measured in the different matrix compartments and were visualized by histology and immunohistochemistry . Already after 7 days in culture the adult human chondroctes looked intact and formed a stable and cell-associated cartilage-specific extracellular matrix in the presence of 10 % calf serum . This could be also demonstrated in the presence of IGF-I . With regards to the collagen content IGF-I at a concentration of 50 ng/ml seemed to induce an equal effect to 10 % serum ; with regards to the proteoglycan content IGF-I at a concentration of 20 ng/ml was equivalent . These encouraging preliminery results may lead to a new approach in tissue engineering for chondrocyte transplantation in combination with their extracellular matrix ." ], "offsets": [ [ 0, 1479 ] ] } ]	[ { "id": "DerOrthopaede.00290100.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "cartilage-specific" ], "offsets": [ [ 15, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290100.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 49, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290100.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "culture" ], "offsets": [ [ 110, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220814" }, { "db_name": "UMLS", "db_id": "C0010453" } ] }, { "id": "DerOrthopaede.00290100.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 118, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] 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DerOrthopaede.00290107.eng.abstr	DerOrthopaede.00290107.eng.abstr	[ { "id": "DerOrthopaede.00290107.eng.abstr-passage-0", "type": "abstract", "text": [ "Bone metabolism is influenced by systemic and local acting hormons . Bone morphogenetic proteins ( BMPs ) as representatives of the latter substances are known to have the ability for ectopic bone formation . Within this study , we investigated the influence of different growth factors on the proliferation- and differentiation rate of osteoblast-like cells . For that purpose , human osteoblast-like cells ( HPOC ) were incubated in the presence of either recombinant BMP-4 of the genome of xenopus laevis ( rxBMP-4), recombinant human BMP 2 ( rhBMP-2), transforming growth factor-ss ( TGF-ss ) or basic fibroblast growth factor ( rh-bFGF ) in two different concentrations each ( 10 ng/ml and 50 ng/ml ) . Cell proliferation was measured within a MTT [ 3- ( 4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromid ] assay , the amount of cell differentiation by the activity of alcaline phosphatase . Rx-BMP-4 induced a differentiation of HPOC to almost the same extent as rhBMP-2, whereas the addition of rh-bFGF , applied at the same concentration , failed to have any influence on cell differentiation . However , rh-bFGF provoked an increase in cell proliferation when compared with unstimulated HPOC , while rhBMP-2 and rxBMP-4 showed no effect on proliferation . TGF-ss influenced bone proliferation as well as differenciation significantly . The equipotent effect of recombinant human BMP-2 and recombinant BMP-4 obtained from Xenopus laevis with regard to differentiation and proliferation of human primary osteoblast-like cells originates either in the fact that target cells have receptors for BMP 2 as well as BMP 4 , or that both BMP's link to the same receptor with almost the same affinity ." ], "offsets": [ [ 0, 1708 ] ] } ]	[ { "id": "DerOrthopaede.00290107.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Bone" ], "offsets": [ [ 0, 4 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "metabolism" ], "offsets": [ [ 5, 15 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025519" }, { "db_name": "UMLS", "db_id": "C0025520" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Bone" ], "offsets": [ [ 69, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "proteins" ], "offsets": [ [ 88, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "ability" ], "offsets": [ [ 172, 179 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085732" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "ectopic" ], "offsets": [ [ 184, 191 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015374" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 192, 196 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "bone formation" ], "offsets": [ [ 192, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005939" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "Bone morphogenetic proteins" ], "offsets": [ [ 69, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0053932" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 272, 278 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "osteoblast-like" ], "offsets": [ [ 337, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029418" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 353, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "growth factors" ], "offsets": [ [ 272, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018284" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s4-t1", "type": 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DerOrthopaede.00290112.eng.abstr	DerOrthopaede.00290112.eng.abstr	[ { "id": "DerOrthopaede.00290112.eng.abstr-passage-0", "type": "abstract", "text": [ "The transplantation of chondrogenic cells in a supportive carrier structure proved to be a promising alternative for the treatment of cartilage defects . In the study presented we focused on the transplantation of allogeneic chondrocytes in a biodegradable polymer scaffold ( PGLA/Polydioxanon ) in articular cartilage defects in a rabbit defect model . Isolated allogeneic chondrocytes embedded in a PGLA polymer scaffold were transplanted into osteochondrogenic defects of the patellar groove and compared with empty defects and transplants of polymer scaffolds without cells . The histological and histochemical analysis was performed after 4 and 12 weeks . The transplant integration and the architecture of the newly formed cartilage were evaluated with a semiquantitative score . After 4 weeks the development of a hyaline-like cartilage tissue of the cell-polymer-transplants was observed , after 12 weeks the defects were nearly completely filled with hyaline-like cartilage . The biodegradation of the polymer construct did not affect the histological structure of the transplant area . Defects of the groups with empty defect and polymer transplants without cells revealed no or insufficient healing indices . The study demonstrated that biodegradable polymers served as suitable carriers for the chondrocyte transplantation , which is due to the in-vitro establishment of a semi-solid cartilage transplant and the resulting effective transplant fixation into the defect . In-vivo the polymer cell transplants seem to provide a supportive microenvironment for the development of hyaline cartilage . The controlled release of morphogenic factors or bioactive molecules and the use of pluripotent mesenchymal progenitor cells opens new perspectives for the optimization of cartilage repair procedures ." ], "offsets": [ [ 0, 1810 ] ] } ]	[ { "id": "DerOrthopaede.00290112.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "transplantation" ], "offsets": [ [ 4, 19 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOrthopaede.00290112.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 36, 41 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290112.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "carrier" ], "offsets": [ [ 58, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007293" }, { "db_name": "UMLS", "db_id": "C0007294" } ] }, { "id": "DerOrthopaede.00290112.eng.abstr-s1-t4", "type": "umlsterm", 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DerOrthopaede.00290120.eng.abstr	DerOrthopaede.00290120.eng.abstr	[ { "id": "DerOrthopaede.00290120.eng.abstr-passage-0", "type": "abstract", "text": [ "Current methods for articular cartilage repair are unpredictable with respect to clinical success . In the present study , we investigated the ability of cells from articular cartilage , perichondrium , and costochondral resting zone to form new cartilage when loaded onto biodegradable scaffolds and implanted into calf muscle pouches of nu/nu mice . Prior in vitro studies showed that platelet derived growth factor-BB ( PDGF-BB ) , but not transforming growth factor beta-1 ( TGF-1), basic fibroblast growth factor , or bone morphogenetic protein-2 promoted proliferation and extracellular matrix sulfation of resting zone chondrocytes without causing the cells to exhibit a hypertrophic chondrocyte phenotype . TGF-1 has also been shown to stimulate chondrogenesis by multipotent chondroprogenitor cells like those in the perichondrium . In addition , PDGF-BB has been shown to modulate chondrogensis by resting zone cells implanted in poly ( D , L-lactide-co-glycolide ) ( PLG ) scaffolds . In the present study we examined whether the cartilage formation is dependent on state of chondrocyte maturation and whether the pretreatment of chondrocytes with growth factors has an influence on the cartilage formation . Scaffolds were manufactured from 80 % PLG with a 75:25 lactide : glycolide ratio and 20 % modified PLG with a 50:50 lactide : glycolide ratio ( PLG-H scaffolds ) . For each experimental group , four nude mice received two identical implants , one in each calf muscle resulting in an N = 8 implants : PLG-H scaffolds alone ; PLG-H scaffolds with cells derived from either the femoral articular cartilage , costochondral periochondrium , or costochondral resting zone cartilage of 125 g male Sprague-Dawley rats ; PLG-H scaffolds with either articular chondrocytes or resting zone chondrocytes that were pretreated with 37,5 ng/ml rhPDGF-BB for 4 h or 24 h before implantation , or with perichondrial cells treated with PDGF-BB plus 0,22 ng/ml rhTGF-1 for 4 h and 24 h . At 4 or 8 weeks after implantation , samples were harvested and analyzed histomorphometrically for new cartilage formed , area of residual implant and area of fibrous connective tissue . Only resting zone cells showed the ability to form new cartilage at a heterotopic site in this study . There was no neocartilage found in nude mice with implants loaded with either articular chondrocytes or perichondrial cells . Pretreatment of resting zone chondrocytes for 4 h prior to implantation significantly increased the amount of newly formed cartilage after 8 weeks and suppressed chondrocyte hypertrophy . The amount of fibrous connective tissue around implants containing either articular chondrocytes or perichondrial cells decreased with time , whereas the amount of fibrous connective tissue around implants containing resting zone chondrocytes pretreated with PDGF-BB was increased . The results showed that resting zone cells can be successfully incorporated into biodegradable porous PLG scaffolds and can induce new cartilage formation in a non-weight-bearing site . Articular chondrocytes as well as perichondrial cells did not have the capacity for neochondrogenesis when implanted heterotopically in this model ." ], "offsets": [ [ 0, 3210 ] ] } ]	[ { "id": "DerOrthopaede.00290120.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 8, 15 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290120.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 30, 39 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290120.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 40, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290120.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 20, 39 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": 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DerOrthopaede.00290129.eng.abstr	DerOrthopaede.00290129.eng.abstr	[ { "id": "DerOrthopaede.00290129.eng.abstr-passage-0", "type": "abstract", "text": [ "Different methods are available for the treatment of osseous defects . In recent years the use of autologous bone was established as the golden standard . However , significant disadvantages are limited availability of the bone graft and its harvest implies additional morbidity for the patient . Alternatives to the use of autologous bone , as allogeneic bone from bone banks or biomaterials like hydroxyapatite are therefore of special interest . However , the currently available methods have severe disadvantages ; allogenic bone carries a high risk of transmitting infectious diseases , most biomaterials show an unsatisfying osseous integration as well as prolonged healing with disability for the patient . Therefore , the aim has to be the development of a biomaterial that is as close as possible to human bone . In this in vitro study the natural bone mineral Bio-Oss/Orthos was used as a matrix for human osteoblast - like cells isolated from bone marrow of healthy patients . Even after three months the cell showed typical osteblast-like behaviour . Histologic evaluation demonstrated the ability of Bio-Oss/Orthos to guide cell growth within its matrix structure and therefore mimics in vivo situation of the healthy bone . The results show that culturing human osteoblast-like cells under standardised conditions is possible and that the combination of human osteoblast-like cell with an appropriate matrix may have the potential for a new treatment option of osseous defects ." ], "offsets": [ [ 0, 1492 ] ] } ]	[ { "id": "DerOrthopaede.00290129.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 10, 17 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290129.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 40, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290129.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 61, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerOrthopaede.00290129.eng.abstr-s2-t1", "type": 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DerOrthopaede.00290145.eng.abstr	DerOrthopaede.00290145.eng.abstr	[ { "id": "DerOrthopaede.00290145.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of our study was to examine the potential of autologous perichondrial tissue to form meniscal replacements . Eighteen mature sheep were used . In 12 animals a complete meniscal resection was performed ; replacement was formed using strips of autologous perichondrial tissue explanted from the lower rib ; six animals with a complete meniscal resection but without any replacement served as controls . In all animals restriction from weight-bearing was achieved by means of transsection and partial achilles-tendon resection . Six animals each , 4 of group T and 2 of group C , were sacrificed after 3 , 6 , and 12 months . Perichondrial grafts and the underlying articular cartilage were removed and investigated by gross macroscopic examination , by means of light and scanning electron microscopy , polarized light examination , and biomechanical tests evaluating the failure stress and tensile modulus . In all transplanted animals a new perichondrial meniscus developed . After 3 months the transplants resembled in size and thickness normal menisci , while in the control animals only small rims of spontaneously grown tissue were detectable . Microscopically , the perichondrial menisci exhibited similarity to normal collagen fiber orientation and cellular characteristics , but , in their central region , areas of calcification disturbed the regular tissue differentiation . In contrast , spontaneously grown tissue in control animals lacked normal fiber orientation and cellularity . Scanning electron-microscopy of perichondrial menisci revealed surface characteristics similar to normal sheep menisci without fissures and lacerations , while the control specimens exhibited such defects . The femoral and tibial cartilage being in contact with the new menisci showed normal surface characteristics apart from one animal with slight surface irregularities . Control animals showed surficial lesions after 3 months , and the extent increased from 6 to 12 months postoperatively . Exemplary microangiographies of the newly grown tissue exhibited a less intense vascularisation after three months when compared to normal menisci with an improving tendency after 6 and 12 months . Biomechanically , values of the failure stress as well as of the tensile modulus of perichondrial menisci were significantly lower than those of normal contralateral menisci . But , spontaneously regenerated tissue in meniscectomized animals exhibited even smaller values also with significant differences towards original menisci . There were no significant differences in values of newly grown perichondrial menisci and spontaneously grown tissue ." ], "offsets": [ [ 0, 2650 ] ] } ]	[ { "id": "DerOrthopaede.00290145.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 82, 88 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290145.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "sheep" ], "offsets": [ [ 137, 142 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036945" } ] }, { "id": "DerOrthopaede.00290145.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "animals" ], "offsets": [ [ 161, 168 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003043" }, { "db_name": "UMLS", "db_id": "C0003062" } ] }, { "id": "DerOrthopaede.00290145.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 279, 285 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290145.eng.abstr-s3-t3", "type": 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DerOrthopaede.00290151.eng.abstr	DerOrthopaede.00290151.eng.abstr	[ { "id": "DerOrthopaede.00290151.eng.abstr-passage-0", "type": "abstract", "text": [ "Hyaline cartilage is thought to be unable to regenerate . All efforts so far - including autologous chondrocyte cell transplantation - to reconstruct cartilage defects in joints have not been totally convincing . However , mesenchymal cells are able to differentiate into chondrocytes under mechanical pressure conditions . In this study , an open porous resorbable two-layer \" bioimplant \" was constructed in which mechanical pressure was exerted onto mesenchymal cells when migrated into the open porous structure of the bioimplant . Differentiation of the cells into chondrocytes was thus induced . The bioimplants were implanted into the medial condyles of nine rabbits and left in place for eight or twelve weeks , respectively . In seven of these cases , cartilage formation was found , in contrary to the controls in which only connective tissue and bone had grown into the empty holes . The new bioimplants have proven their effectiveness in cartilage defect repair and might evolve in the future as a new alternative treatment of full thickness defects of joint surfaces ." ], "offsets": [ [ 0, 1081 ] ] } ]	[ { "id": "DerOrthopaede.00290151.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Hyaline" ], "offsets": [ [ 0, 7 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020191" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 8, 17 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "All" ], "offsets": [ [ 58, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023449" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "efforts" ], "offsets": [ [ 62, 69 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015264" } ] }, { "id": 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"db_id": "C0243067" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "joints" ], "offsets": [ [ 171, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "cell transplantation" ], "offsets": [ [ 112, 132 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206153" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 235, 240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 272, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290151.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "pressure" ], "offsets": [ [ 302, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033095" } ] }, { "id": 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DerOrthopaede.00290158.eng.abstr	DerOrthopaede.00290158.eng.abstr	[ { "id": "DerOrthopaede.00290158.eng.abstr-passage-0", "type": "abstract", "text": [ "Successful transplantation of autologous chondrocytes for repair of articular cartilage defects requires an undisturbed matrix-synthesis of the transplanted cells . This , in turn , is dependent on the composition of the synovial fluid ( SF ) of the respective joint . We addressed the question whether analysis of a patient's SF can predict the rate of matrix-synthesis of articular cartilage exposed to this SF in vitro . SF was obtained from 115 patients with disorders of the knee , including gonarthrosis ( n = 44 ) , meniscal tears ( n = 10 ) , rheumatoid arthritis ( n = 53 ) , and reactive arthritides ( n = 8 ) . In the SF , the following parameters were determined : Interleukin-1, IL-6, IL-8, IL-1-RA, TNF , Insulin-like growth-factor I ( IGF-I ) , IGF-II , IGF-binding protein-2 ( IGFBP-2), IGFBP-3 as well as total proteinase activity and total collagenase activity . To assess the effect of SF on the matrix synthesis of articular chondrocytes , bovine cartilage was incubated in the presence of SF , and the rate of proteoglycan synthesis subsequently determined . In some cases , a monoclonal antibody directed against IGF-I was added . SF from patients with OA or trauma , respectively , stimulated PG-synthesis of bovine cartilage more markedly than did SF from patients with rheumatic arthritides . On the average , 60 percent of the SF-induced increase of cartilage matrix synthesis could be titrated out by an anti-IGF-I-AB . The best predictor for the SF-effects on PG-synthesis of exposed cartilage was the proportion of free IGF-I ( r = 0.573 , p 0.001 , Spearman rank correlation ) followed by the SF-concentrations of IGF-I ( with a positive sign ) , IGFBP-3, IL-1, and TNF ( all with a negative sign ) . According to our data , IGF-I is the most important anabolic factor in human SF with respect to cartilage PG-synthesis . The proportion of free IGF-I seems to be of special importance in this regard . Low SF-levels of free IGF-I could be identified as a possible risk-factor for a sub-optimal protoeglycan synthesis of chondrocytes exposed to this synovial milieu ." ], "offsets": [ [ 0, 2096 ] ] } ]	[ { "id": "DerOrthopaede.00290158.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "transplantation" ], "offsets": [ [ 11, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029216" }, { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "chondrocytes" ], "offsets": [ [ 41, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0225369" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 58, 64 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 78, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 88, 95 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 157, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 68, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 261, 266 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "synovial fluid" ], "offsets": [ [ 221, 235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039097" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 384, 393 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 374, 393 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "in vitro" ], "offsets": [ [ 413, 421 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021135" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 449, 457 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s4-t2", "type": 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], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s8-t6", "type": "umlsterm", "text": [ "arthritides" ], "offsets": [ [ 1304, 1315 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003864" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s8-t7", "type": "umlsterm", "text": [ "rheumatic arthritides" ], "offsets": [ [ 1294, 1315 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003873" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 1376, 1385 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 1512, 1521 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "IGF-I" ], "offsets": [ [ 1549, 1554 ] ], "normalized": [ { "db_name": 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"DerOrthopaede.00290158.eng.abstr-s13-t3", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-r9-t1.1-t2.1", "type": "produces", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t2", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-r10-t4.1-t3.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s10-t4", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t3", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-r11-t3.1-t1.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t3", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s10-r12-t2.1-t4.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t2", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s10-t4", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s11-r1-t2.1-t1.1", "type": "produces", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t2", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s11-r2-t1.1-t2.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t2", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s13-r1-t1.1-t3.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t3", "normalized": [] }, { "id": "DerOrthopaede.00290158.eng.abstr-s13-r2-t3.1-t1.1", "type": "produces", "arg1_id": "DerOrthopaede.00290158.eng.abstr-s13-t3", "arg2_id": "DerOrthopaede.00290158.eng.abstr-s13-t1", "normalized": [] } ]
DerOrthopaede.00290174.eng.abstr	DerOrthopaede.00290174.eng.abstr	[ { "id": "DerOrthopaede.00290174.eng.abstr-passage-0", "type": "abstract", "text": [ "The load limit of a tendon is expressed by the not linear force/lenghtening behavior . It is determined by the interrelation between load and load-bearing capacity . The load of a tendon results from exogenous , endogenous and temporal factors . The property factors and the aging influence the load-bearing capacity of a tendon . Partial ruptures show necrosis , calcification and fiber swelling . The attachment area shows a mineralization of the cartilage zone , a loss of the collagen fibrils and calcifications . The tendon ruptur knows extrinsic and intrinsic causes . Primary are micro and macrovascular tendon alterations , usually favour the rupture of tendons ." ], "offsets": [ [ 0, 671 ] ] } ]	[ { "id": "DerOrthopaede.00290174.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 20, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "behavior" ], "offsets": [ [ 76, 84 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004927" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 180, 186 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 322, 328 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "ruptures" ], "offsets": [ [ 339, 347 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "necrosis" ], "offsets": [ [ 353, 361 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027540" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "calcification" ], "offsets": [ [ 364, 377 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006660" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 449, 458 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 480, 488 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "calcifications" ], "offsets": [ [ 501, 515 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006660" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 522, 528 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "causes" ], "offsets": [ [ 566, 572 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 611, 617 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "rupture" ], "offsets": [ [ 651, 658 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290174.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "tendons" ], "offsets": [ [ 662, 669 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290174.eng.abstr-s5-r1-t2.1-t1.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t2", "arg2_id": "DerOrthopaede.00290174.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-r2-t2.1-t3.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t2", "arg2_id": "DerOrthopaede.00290174.eng.abstr-s8-t3", "normalized": [] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-r3-t1.1-t2.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t1", "arg2_id": "DerOrthopaede.00290174.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-r4-t1.1-t3.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t1", "arg2_id": "DerOrthopaede.00290174.eng.abstr-s8-t3", "normalized": [] }, { "id": "DerOrthopaede.00290174.eng.abstr-s5-r5-t3.1-t1.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t3", "arg2_id": 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"DerOrthopaede.00290174.eng.abstr-s8-r4-t3.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290174.eng.abstr-s8-t3", "arg2_id": "DerOrthopaede.00290174.eng.abstr-s8-t2", "normalized": [] } ]
DerOrthopaede.00290182.eng.abstr	DerOrthopaede.00290182.eng.abstr	[ { "id": "DerOrthopaede.00290182.eng.abstr-passage-0", "type": "abstract", "text": [ "This review describes structure , function and healing of tendinous tissue and discusses new biologically based treatment options to modulate tendon healing . The repair process after tendon rupture results in a morphologically different and biomechanically inferior structure compared to a normal tendon . The collagen fibril diameters are decreased months after the traumatic lesion and show also different phenotypes . We know that cytokines and growth factors are key components for normal tissue development and regulate wound healing processes . Some growth factors have been detected to influence tenocytes by promoting cell proliferation and matrix synthesis . Application of the adequate growth factors at certain periods during the repair process might improve the healing result after tendon rupture . However , most of these growth factors are proteins which are rapidly metabolized by the organism . Transfer of growth factor genes into tenocytes might eliminate this problem by a continuous local release of growth factors at the healing site ." ], "offsets": [ [ 0, 1058 ] ] } ]	[ { "id": "DerOrthopaede.00290182.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "review" ], "offsets": [ [ 5, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282443" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 34, 42 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 68, 74 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 112, 121 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 142, 148 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 163, 169 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 184, 190 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "rupture" ], "offsets": [ [ 191, 198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 298, 304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 311, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "phenotypes" ], "offsets": [ [ 409, 419 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031437" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "cytokines" ], "offsets": [ [ 435, 444 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079189" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 449, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 494, 500 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 501, 512 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "wound" ], "offsets": [ [ 526, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021501" }, { "db_name": "UMLS", "db_id": "C0043250" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "growth factors" ], "offsets": [ [ 449, 463 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018284" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "wound healing" ], "offsets": [ [ 526, 539 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 557, 563 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": 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DerOrthopaede.00290188.eng.abstr	DerOrthopaede.00290188.eng.abstr	[ { "id": "DerOrthopaede.00290188.eng.abstr-passage-0", "type": "abstract", "text": [ "Tendon sutures belong to the bases of surgical activity . Particularly in the last decades these sutures experienced a substantial upswing by the introduction of new techniques and materials . Target is to reestablish the tendon function . In order to achieve this target , it requires knowledge of tendon healing . An outline of suture materials , in particular specific suture techniques as well as the subsequent treatment is given . With different localizations of the tendon lesions one deals ." ], "offsets": [ [ 0, 499 ] ] } ]	[ { "id": "DerOrthopaede.00290188.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Tendon" ], "offsets": [ [ 0, 6 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "sutures" ], "offsets": [ [ 7, 14 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038969" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 38, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "sutures" ], "offsets": [ [ 97, 104 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038969" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 166, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 222, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 229, 237 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 286, 295 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 299, 305 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 379, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 416, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "suture techniques" ], "offsets": [ [ 372, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038968" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 473, 479 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290188.eng.abstr-s3-r1-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290188.eng.abstr-s6-t1", "arg2_id": "DerOrthopaede.00290188.eng.abstr-s5-t2", "normalized": [] } ]
DerOrthopaede.00290196.eng.abstr	DerOrthopaede.00290196.eng.abstr	[ { "id": "DerOrthopaede.00290196.eng.abstr-passage-0", "type": "abstract", "text": [ "Since the life span of our society is increasing and the expectation of high functional demands is growing more and more older people take part in sports activities emphasises the necessity of early diagnosis of rotator cuff lesions and their correct treatment . The goal of any diagnostic means should be a proper treatment of rotator cuff lesions according to the detected pathology . New arthroscopic techniques to surgically reconstruct rotator cuff tears have brought the operative repair techniques another step further . In cases of large and complex cuff tears the surgeon can individually select an adequate reconstruction procedure which includes anatomical- , partial- , tendon-transfer and muscle-transfer repairs . In cases of irreparable tears with cuff-tear arthropathy and consecutive superior migration of the humeral head hemiarthroplasty or the inverse deltoid prosthesis have to be considered . Based on clinical , radiological and arthroscopic findings we developed algorithms that will lead to the best suited procedure for a given lesion ." ], "offsets": [ [ 0, 1062 ] ] } ]	[ { "id": "DerOrthopaede.00290196.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "life" ], "offsets": [ [ 10, 14 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376558" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "society" ], "offsets": [ [ 27, 34 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037455" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "older" ], "offsets": [ [ 121, 126 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "people" ], "offsets": [ [ 127, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027361" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "sports" ], "offsets": [ [ 147, 153 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038039" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 199, 208 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 251, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "sports activities" ], "offsets": [ [ 147, 164 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038039" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "rotator cuff" ], "offsets": [ [ 212, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085515" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "goal" ], "offsets": [ [ 267, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018017" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "diagnostic" ], "offsets": [ [ 279, 289 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 315, 324 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "pathology" ], "offsets": [ [ 375, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "rotator cuff" ], "offsets": [ [ 328, 340 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085515" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 404, 414 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tears" ], "offsets": [ [ 454, 459 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043246" }, { "db_name": "UMLS", "db_id": "C0035955" }, { "db_name": "UMLS", "db_id": "C0039409" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 487, 493 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 494, 504 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "rotator cuff" ], "offsets": [ [ 441, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085515" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "tears" ], "offsets": [ [ 563, 568 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043246" }, { "db_name": "UMLS", "db_id": "C0035955" }, { "db_name": "UMLS", "db_id": "C0039409" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 632, 641 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "anatomical-" ], "offsets": [ [ 657, 668 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "tendon-transfer" ], "offsets": [ [ 682, 697 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "tendon-transfer" ], "offsets": [ [ 682, 697 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040671" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "muscle-transfer" ], "offsets": [ [ 702, 717 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "muscle-transfer" ], "offsets": [ [ 702, 717 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040671" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "repairs" ], "offsets": [ [ 718, 725 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "tears" ], "offsets": [ [ 752, 757 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043246" }, { "db_name": "UMLS", "db_id": "C0035955" }, { "db_name": "UMLS", "db_id": "C0039409" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "arthropathy" ], "offsets": [ [ 773, 784 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022408" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "migration" ], "offsets": [ [ 810, 819 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600210" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 835, 839 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "prosthesis" ], "offsets": [ [ 880, 890 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0525024" }, { "db_name": "UMLS", "db_id": "C0175649" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 965, 973 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "algorithms" ], "offsets": [ [ 987, 997 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002045" } ] }, { "id": "DerOrthopaede.00290196.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 1032, 1041 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290196.eng.abstr-s1-r1-t2.1-t6.2", "type": "carries_out", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t2", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r2-t9.1-t6.2", "type": "location_of", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s1-t9", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r3-t3.1-t5.1", "type": "performs", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t3", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s5-t5", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r4-t6.1-t6.2", "type": "precedes", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r5-t2.1-t7.1", "type": "carries_out", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t2", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r6-t9.1-t7.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s1-t9", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r7-t6.1-t7.1", "type": "precedes", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r8-t3.1-t6.1", "type": "performs", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t3", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r9-t2.1-t6.1", "type": "carries_out", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t2", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r10-t9.1-t6.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s1-t9", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s4-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r11-t3.1-t6.2", "type": "performs", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s6-t3", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOrthopaede.00290196.eng.abstr-s1-r12-t9.1-t3.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290196.eng.abstr-s1-t9", "arg2_id": "DerOrthopaede.00290196.eng.abstr-s6-t3", "normalized": [] }, { "id": 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DerOrthopaede.00290209.eng.abstr	DerOrthopaede.00290209.eng.abstr	[ { "id": "DerOrthopaede.00290209.eng.abstr-passage-0", "type": "abstract", "text": [ "Ruptures of the long head of the M. biceps humeri are commonly caused by degenerative changes within the tendon . They are associated with pathologies of the subacromial space . The loss of power regarding elbow flexion and supination amounts to 8 to 21 % after conservative treatment . Refixation offers a small but evident improvement of flexion and supination power . Especially endurance is improved . The number of cases with remaining light or marked weakness is reduced by more than 50 % . Deformity by the slipped muscle can be corrected effectively . Function of the glenohumeral joint can only be improved if associated subacromial problems are identified and treated simultaneously . As complications are uncommon surgery should be recommended to young and active patients and should at least be offered to less active patients . Ruptures of the distal tendon are less common . Thirteen patients were re-examined after operative repair for distal biceps tendon avulsion and 277 reported cases were reviewed . After conservative management ( n = 20 ) the power of flexion will remain reduced by 30 %-40 % , that of supination by more than 50 % . The loss of flexion power , as well as the deformity can be diminished by attachment of the distal biceps to the brachialis muscle ( n = 22 ) . The anatomic reinsertion ( n = 248 ) additionally reduces the loss of supination power to 0 %-25 % , but bears a higher risk of complications . Using the ' double-incision technique ' ( n = 105 of 248 ) does not decrease the risk of nerval lesions but increases the incidence of radioulnar synostosis . The use of suture anchors provides a nice way of fixation of the tendon but does not facilitate the approach to the tuberosity . The distal biceps tendon rupture should be treated operatively . The adequate method of repair is to be determined individually ." ], "offsets": [ [ 0, 1861 ] ] } ]	[ { "id": "DerOrthopaede.00290209.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Ruptures" ], "offsets": [ [ 0, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290209.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 21, 25 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290209.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "humeri" ], "offsets": [ [ 43, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020164" } ] }, { "id": "DerOrthopaede.00290209.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 105, 111 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290209.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "pathologies" ], "offsets": [ [ 139, 150 ] ], "normalized": [ { "db_name": "UMLS", 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DerOrthopaede.00290216.eng.abstr	DerOrthopaede.00290216.eng.abstr	[ { "id": "DerOrthopaede.00290216.eng.abstr-passage-0", "type": "abstract", "text": [ "Injuries of the flexor tendon are usually open injuries . In most cases primary treatment is therefore seldom performed by orthopaedic surgeons . This is different for injuries of the extensor tendon . Three quarters of injuries of the extensor tendon are closed injuries . Therefore we do go into primary and secondary reconstruction of the flexor tendon , but focus on primary and secondary reconstruction of the extensor tendon in the most common zones ( 1 , Th I , 3 , Th III ) ." ], "offsets": [ [ 0, 483 ] ] } ]	[ { "id": "DerOrthopaede.00290216.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Injuries" ], "offsets": [ [ 0, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "flexor" ], "offsets": [ [ 16, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175090" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 23, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "open" ], "offsets": [ [ 42, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0266061" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 47, 55 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 80, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 168, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 193, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 220, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 263, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 310, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "flexor" ], "offsets": [ [ 342, 348 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175090" } ] }, { "id": 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DerOrthopaede.00290235.eng.abstr	DerOrthopaede.00290235.eng.abstr	[ { "id": "DerOrthopaede.00290235.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of acute of Achilles tendon rupture experienced a dynamic development in the last ten years . Decisive for this development was the application of MRI and above all the ultrasonography in the diagnostics of the pathological changes and injuries of tendons . The question of ruptue morphology as well as different courses of healing could be now evaluated objectively . These advances led consequently to new modalities in treatment concepts and rehabilitation protocols . The decisive input for improvements of the outcome results and particularly the shortening of the rehabilitation period came with introduction of the early functional treatment in contrast to immobilizing plaster treatment . In a prospective randomized study ( 1987-1989 ) at the Trauma Dept . of the Hannover Medical School could show no statistical differences comparing functional non-operative with functional operative therapy with a special therapy boot ( Variostabil/Adidas ) . The crucial criteria for therapy selection results from the sonografically measured position of the tendon stumps in plantar flexion ( 20 ° ) . With complete adaptation of the tendons ' ends surgical treatment does not achieve better results than non-operative functional treatment in term of tendon healing and functional outcome . Regarding the current therapeutic standards each method has is advantages and disadvantages . Both , the operative and non-operative functional treatment enable a stable tendon healing with a low risk of rerupture ( 1-2 % ) . Meanwhile there is consensus for early functional aftertreatment of the operated Achilles ' tendons . There seems to be a trend towards non-operative functional treatment in cases of adaquate sonografical findings , or to minimal invasive surgical techniques ." ], "offsets": [ [ 0, 1790 ] ] } ]	[ { "id": "DerOrthopaede.00290235.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 4, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290235.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 35, 41 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290235.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "rupture" ], "offsets": [ [ 42, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290235.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 72, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", 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DerOrthopaede.00290251.eng.abstr	DerOrthopaede.00290251.eng.abstr	[ { "id": "DerOrthopaede.00290251.eng.abstr-passage-0", "type": "abstract", "text": [ "Complete traumatic rupture of the tibialis posterior tendon is absolutely rare . From the scarce case reports in the medical literature a extreme pronation-abduction or pronation-external rotation mechanism according to the Lauge-Hansen classification can be presumed , leading to a malleolar fracture because of forced pronation , external rotation and dorsiflexion of the foot . With primary suture the prognosis is favorable . Traumatic dislocations , mostly with luxatio pedis sub talo , are treated by atraumatic reduction and refixation of the retinaculum . Again , the prognosis is favorable . Incomplete traumatic rupture of the tibialis posterior tendon with development of posttraumatic pes plano valgus , according to case reports and our own experience result from severe pronation-external rotation-soft tissue injuries as well as with pronation-abduction or pronation-external rotation-type ankle fractures . In these cases no macroscopic rupture of the tendon is evident , however occult interstitial microruptures can occur because of excessive stretching , which can be determined histologically . If conservative measures fail , a modified Evans osteotomy to lenghten the lateral foot column is indicated . Degenerative complete and incomplete ruptures of the tibialis posterior tendon are predominantly seen in women more than 42 years old . Staging of this entity can be achieved with clinical tests ( muscular force , external rotation ) , ultrasound , weight-bearing x-rays , CT and MRT . According to the degree of decompensation of tendon function , treatment consists of augmentation , modified Evans procedure or triple arthrodesis of the hindfoot ." ], "offsets": [ [ 0, 1675 ] ] } ]	[ { "id": "DerOrthopaede.00290251.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "rupture" ], "offsets": [ [ 19, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290251.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 43, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290251.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 53, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290251.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "traumatic rupture" ], "offsets": [ [ 9, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290251.eng.abstr-s2-t1", 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DerOrthopaede.00290274.eng.abstr	DerOrthopaede.00290274.eng.abstr	[ { "id": "DerOrthopaede.00290274.eng.abstr-passage-0", "type": "abstract", "text": [ "Fracture care in a geriatric population should lead to a mobilisation with full weight bearing as soon as possible after the accident . Osteoporosis and associated preexisting disease influences the kind of fracture care as well as the social situation . A retrospective analysis of 888 consecutive patients from 1994 to 1998 showed that the fracture risk for a second independent bony lesion was 5,2 % in this population with a mean age of 83,4 years ( 75y-97,2 y ) . 946 fractures were treated operatively with a overall reoperation rate of 10 % . 3,1 % were soft tissue revisions due to infection , 2,0 % were because of implant failure in connection with a deep infection and 5,2 % of the reoperation were indicated because of implant failure alone . Distribution of complications showed the advantage of closed , indirect reduction and intramedullary devices and primary hemiarthroplasty in femoral and humeral head fractures ." ], "offsets": [ [ 0, 932 ] ] } ]	[ { "id": "DerOrthopaede.00290274.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Fracture" ], "offsets": [ [ 0, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290274.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "care" ], "offsets": [ [ 9, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0150499" } ] }, { "id": "DerOrthopaede.00290274.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "geriatric" ], "offsets": [ [ 19, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0017469" } ] }, { "id": "DerOrthopaede.00290274.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "population" ], "offsets": [ [ 29, 39 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032659" } ] }, { 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DerOrthopaede.00290281.eng.abstr	DerOrthopaede.00290281.eng.abstr	[ { "id": "DerOrthopaede.00290281.eng.abstr-passage-0", "type": "abstract", "text": [ "Any medical procedure must be legally authorized by the patient , giving informed consent . This prerequisite is based on the right to self determination . Otherwise a medical procedure is considered as physical injury . Thus , the way , how a specific procedure is performed , predominantly depends on the patient's will . The attending physician's duty is to find out this will , which is especially important when old patients and patients incapable of giving valid consent are involved . Before the procedure the physician has to have a confidential talk with the patient . He has to point out the best treatment possible considering the individual circumstances of the patient's life . The physician has to find out , weather the patient is competent to refuse or consent to treatement . Furthermore the consultation is an opportunity to diminish the patient's fear and to increase his confidence . The main problem treating old patients is that they often lack the mental ability for appreciation of the nature of the situation . One has to differentiate between the physiological mental decay and dementia or psychiatric diseases . In these cases a third party consent is necessary ." ], "offsets": [ [ 0, 1190 ] ] } ]	[ { "id": "DerOrthopaede.00290281.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 12, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290281.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 56, 63 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290281.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 126, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerOrthopaede.00290281.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "self" ], "offsets": [ [ 135, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036588" } ] }, { "id": "DerOrthopaede.00290281.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "determination" ], "offsets": [ [ 140, 153 ] ], 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DerOrthopaede.00290288.eng.abstr	DerOrthopaede.00290288.eng.abstr	[ { "id": "DerOrthopaede.00290288.eng.abstr-passage-0", "type": "abstract", "text": [ "Femoral neck fractures are frequent fractures of the elderly . They can be treated by the use of dynamic hip screws , lag screws , bipolar hemiprotheses or total hip replacement . The results are markedly influenced by the timing of the operation and the choice of the implant . Using the Garden classification of femoral neck fracture we demonstrate a different therapeutic approach according to Garden stadium I-IV ." ], "offsets": [ [ 0, 418 ] ] } ]	[ { "id": "DerOrthopaede.00290288.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 8, 12 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 13, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 36, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "elderly" ], "offsets": [ [ 53, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "Femoral neck fractures" ], "offsets": [ [ 0, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015806" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 90, 93 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 105, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 109, 115 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 122, 128 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 162, 165 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "hip replacement" ], "offsets": [ [ 162, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0392806" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "total hip replacement" ], "offsets": [ [ 156, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040508" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "operation" ], "offsets": [ [ 237, 246 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "choice" ], "offsets": [ [ 255, 261 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008300" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "classification" ], "offsets": [ [ 296, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008902" }, { "db_name": "UMLS", "db_id": "C0008903" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 322, 326 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "fracture" ], "offsets": [ [ 327, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 363, 374 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOrthopaede.00290288.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "femoral neck fracture" ], "offsets": [ [ 314, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015806" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290288.eng.abstr-s1-r1-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290288.eng.abstr-s4-t1", "arg2_id": 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DerOrthopaede.00290294.eng.abstr	DerOrthopaede.00290294.eng.abstr	[ { "id": "DerOrthopaede.00290294.eng.abstr-passage-0", "type": "abstract", "text": [ "Trochanteric fractures frequently occur in elder patients with severe osteopenia . These fractures are highly unstable . Conservative treatment is not indicated because of the long period of immobilisation until fracture healing is achieved . Simple fractures ( A1) can be succesfully fixed by either plate-hip screw systems like Dynamic Hip Screw ( DHS ) or nail-hip screw systems ( Gamma-Nail , Proximal Femur Nail , Classic Nail ) . As a result of biomechanical and clinical trials the intramedullary implants should be prefered for fixation of more comminuted fractures ( Type A2.2, A3.3) and subtrochanteric fractures . For ipsilateral femoral shaft and trochanteric fractures long nail-hip screw-systems are recommended like the long PFN or the long Gamma nail . In about 90 % of the patients with trochanteric fractures postoperative weight bearing can be achieved by internal fixation if gliding systems are applied . Intraoperative and postoperative complications however occur more frequently after the implantation of Gamma-Nail than after application of a DHS . Other implants like Ender Nails , 130 ° angled plate or twisted plate are not further recommended ." ], "offsets": [ [ 0, 1173 ] ] } ]	[ { "id": "DerOrthopaede.00290294.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 13, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "elder" ], "offsets": [ [ 43, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 49, 57 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "osteopenia" ], "offsets": [ [ 70, 80 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029453" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "Trochanteric fractures" ], "offsets": [ [ 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} ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "Hip" ], "offsets": [ [ 338, 341 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "nail-hip" ], "offsets": [ [ 359, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027342" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "nail-hip" ], "offsets": [ [ 359, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "screw" ], "offsets": [ [ 368, 373 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t9", "type": "umlsterm", "text": [ "Gamma-Nail" ], "offsets": [ [ 384, 394 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027342" } ] }, { "id": "DerOrthopaede.00290294.eng.abstr-s4-t10", "type": 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DerOrthopaede.00290302.eng.abstr	DerOrthopaede.00290302.eng.abstr	[ { "id": "DerOrthopaede.00290302.eng.abstr-passage-0", "type": "abstract", "text": [ "Spinal injuries referring to banal falls are common injuries in elderly persons . Up to 55 years of age spinal fractures are more frequent in men while its opposite in older persons . There are two typical lesions : odontoid fracture in the upper cervical spine and compression fracture in thoracolumbar spine . Odontoid fracture is the most frequent lesion in cervical spine in the elderly . This is caused by trabecular structure of dens axis and spine's stiffness in old age . Instable fractures in extension type II are most common . In many cases the instability of the lesion is hidden and can be first seen in functional examination controlled by x-ray . Conservative treatment is efficient in stable lesions type III while there is a high risk for pseudarthrosis in treatment of instable lesions in elderly with Halo Fixateur e . g . We think that the best operation for these fractures is the anterior screw fixation . If this is not sufficient because of low bone mass or early dislocation of the screws a dorsal fusion C1/C2 with transarticular screwing e . g . should be done . Because of rare symptoms thoracolumbar fractures in osteoporosis are hidden frequently . In many cases it's not easy to distinguish acute lesions from healed fractures or tumor lesions . Neurological deficit is rare . Therefore there are just few compression fractures ( A type ) that have to be treated operatively . Instable lesions type B and C must be operated as well in the elderly as in the young . Because of low bone mass in elderly the dorsal instrumentation should include more than just the two injured segments . An even more adequate stabilisation is done with an additional vertebral replacement ." ], "offsets": [ [ 0, 1702 ] ] } ]	[ { "id": "DerOrthopaede.00290302.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 7, 15 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290302.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 52, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290302.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "elderly" ], "offsets": [ [ 64, 71 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" } ] }, { "id": "DerOrthopaede.00290302.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "persons" ], "offsets": [ [ 72, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027361" } ] }, { "id": "DerOrthopaede.00290302.eng.abstr-s1-t5", 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DerOrthopaede.00290318.eng.abstr	DerOrthopaede.00290318.eng.abstr	[ { "id": "DerOrthopaede.00290318.eng.abstr-passage-0", "type": "abstract", "text": [ "Every 15th case of a bone fracture in patients aged more than 65 years concerns the distal radius in Germany . This means the second rank of all geriatric fractures following fractures of the hip . According to the approved and increased apply of operative stabilisation there are arising more and more reports upon poor results of nonsurgical treatment . Especially in older patients the main reason for the discontented outcome of conservative management is osteoporosis , which is an affirmative circumstance for the genesis of fracture but also for secondary malaligment of comminuted thin cortical walls and crushed porotic cancellous bone . The rational of this perception is either filling artificial bonelike tissue - avoiding the need of harvest cancellous bone graft from a second surgical site - into the resultant cavity following reduction , or supplementary transstyloidal or intrafocal K-wiring until remodeling is obtained within an average of 10 weeks . Both arrangements should be secured in addition with a transarticular external fixation . According to a literature review and our own experiences of 92 follow up cases of distal radius fractures in patients who were older than 65 years this procedure seems to be superior at present for A-2, A-3 and most cases of type-C fractures of the distal radius , despite the disadvantage of joint immobilisation for about 5 weeks . Type B-fractures , however , should be provided better with an internal fixation . Sudeck's algodystrophia is the mostly serious complication of the distal radius fracture and its treatment in older patients . Recognising punctually neurovegetative stimulated patients , treat them cautiously and coming in on their special situation is usually the best way to reduce this risk . To pay attention to the topography of the nerves during the application of the pins and to act at the first signs of complications immediately is also very important . We examined 92 patients who were older than 65 years with a fracture of the distal end of the radius in a follow up study . In this group we treated 62 distal radius fractures of the type A and C of the AO classification with an transarticular external fixateur and with supplementary measures if necessary . Additionally we filled the bone cavity with an artificial bone graft ( Endobon ) following closed reduction in 32 cases , 12 times a complementary K-wiring was added and in 8 cases the external fixateur was combined with both . Sudeck's disease appeared in 1.1 % of all cases . In 5 cases we recorded complications with an obligation to treatment as well . Lesion of the superficial branch of the radial nerve were noted in 2 cases ( 2,1 % ) , as far as we extended the surgical approach for the pin application . Technical problems from the site of the external fixateur appeared in 3 cases , two of them could be attributed to an infirmity of the fixateurs ball joints which is now eliminated by the producer . 4 patients with a type-B fracture was provided by plating , additionally 4 patients with a type-C fracture because of non-compliance . The external fixateur is an essential part of a differentiated treatment with reference to the several types of distal radius fractures in older patients ." ], "offsets": [ [ 0, 3255 ] ] } ]	[ { "id": "DerOrthopaede.00290318.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 21, 25 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290318.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "fracture" ], "offsets": [ [ 26, 34 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290318.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 38, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290318.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "radius" ], "offsets": [ [ 91, 97 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034627" } ] }, { "id": "DerOrthopaede.00290318.eng.abstr-s1-t5", "type": "umlsterm", 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DerOrthopaede.00290327.eng.abstr	DerOrthopaede.00290327.eng.abstr	[ { "id": "DerOrthopaede.00290327.eng.abstr-passage-0", "type": "abstract", "text": [ "In contrast to distal humeral fractures , humeral head fractures represent a common injury to the old patient . For both fracture localizations osteoporosis and multi-morbidity are of significant importance . The classification for humeral head fractures in one- , two- , three- and four-part fractures is generally accepted . Valgus impacted head fractures as well as head-splitting fractures are considered a seperate entity . In none or minimally displaced fractures good functional results are achieved by conservative means . Although numerous therapeutical procdure are offered in the treatment of displaced fractures of the proximal humerus the result are often disappointing . Generally , minimal invasive surgical procedures should be preferred . However , in dislocated multi-part fractures a primary humeral head replacement is often the treatment of choice . In patients with mutifarious morbidity a conservative treatment is always to be included into the therapeutical considerations . Distal fractures of the humerus are classified into extraarticular , intraarticular unicondylar and intraarticular bicondylar fractures . The therapeutical recommendations , also in the elderly , is relatively homogenous : primary open reduction and internal fixation ( ORIF ) should be carried out aiming for an early postoperative functional treatment . Depending from soft tissue conditions and accompanying injuries the functional results are often good or moderate and are generally comparable to those of younger patients . Following a correct indication for surgical intervention the main priority for both distal and proximal humeral fractures is an early definitive surgical treatment ." ], "offsets": [ [ 0, 1695 ] ] } ]	[ { "id": "DerOrthopaede.00290327.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "contrast" ], "offsets": [ [ 3, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0110625" } ] }, { "id": "DerOrthopaede.00290327.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 30, 39 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290327.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 50, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290327.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 55, 64 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290327.eng.abstr-s1-t5", "type": 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Intravascular coagulation with fibrin thrombosis begins in the capillaries and sinusoids of the intraosseous microcirculation , and residual venous thrombosis is more likely to occur if there is coexistent hypofibrinolysis ." ], "offsets": [ [ 0, 593 ] ] } ]	[ { "id": "DerOrthopaede.00290370.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "fractures" ], "offsets": [ [ 8, 17 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290370.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "dislocations" ], "offsets": [ [ 25, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012691" } ] }, { "id": "DerOrthopaede.00290370.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 53, 57 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290370.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "injury" ], "offsets": [ [ 86, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { 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DerOrthopaede.00290389.eng.abstr	DerOrthopaede.00290389.eng.abstr	[ { "id": "DerOrthopaede.00290389.eng.abstr-passage-0", "type": "abstract", "text": [ "The pathomorphologies of non-traumatic femoral head osteonecroses ( ON ) are usually similar , despite various known pathogenetic factors . The size and position of the subchondral bone and marrow segment , becoming necrotic after the ischemic event ( s ) , and the kind of repair processes determine the time course and thus the fate of this hip joint disease ." ], "offsets": [ [ 0, 362 ] ] } ]	[ { "id": "DerOrthopaede.00290389.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 47, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "osteonecroses" ], "offsets": [ [ 52, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 39, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 181, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "marrow" ], "offsets": [ [ 190, 196 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376152" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "ischemic" ], "offsets": [ [ 235, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022116" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 274, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "time" ], "offsets": [ [ 305, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040223" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 343, 346 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 347, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 353, 360 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "hip joint" ], "offsets": [ [ 343, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019558" } ] }, { "id": "DerOrthopaede.00290389.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "joint disease" ], "offsets": [ [ 347, 360 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022408" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290389.eng.abstr-s1-r1-t1.1-t3.1", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290389.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290389.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOrthopaede.00290389.eng.abstr-s1-r2-t1.1-t2.1", "type": "location_of", "arg1_id": 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DerOrthopaede.00290403.eng.abstr	DerOrthopaede.00290403.eng.abstr	[ { "id": "DerOrthopaede.00290403.eng.abstr-passage-0", "type": "abstract", "text": [ "The natural course of Osteonecrosis ( ON ) of the femoral head has yet not been evaluated sufficiently . Especially in the early forms of the disease ( ARCO 0 to II ) without collapse of the femoral head , useful information on the natural course could only be collected since the routine use of MR-imaging . The unspecific findings in ARCO stage I with negative radiographs are potential reversible . The \" point of no return \" already lies in the irreversible ARCO stage II in almost all cases . Prognosis for further progression for both early stages depends primarily on the extension and location of the lesion . Only the rare , small to medium sized lesions in the medial or central location may have a good prognostic course over a period of more than five years . The much more common large sized and lateral located lesions will have a probability of about 80 % to progress to femoral head collapse within two years ." ], "offsets": [ [ 0, 926 ] ] } ]	[ { "id": "DerOrthopaede.00290403.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Osteonecrosis" ], "offsets": [ [ 22, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" }, { "db_name": "UMLS", "db_id": "C0027543" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 58, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 50, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "forms" ], "offsets": [ [ 129, 134 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 142, 149 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 199, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 289, 292 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 191, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 324, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "radiographs" ], "offsets": [ [ 363, 374 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043299" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "stage" ], "offsets": [ [ 467, 472 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Prognosis" ], "offsets": [ [ 498, 507 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033325" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "stages" ], "offsets": [ [ 547, 553 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 739, 745 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "probability" ], "offsets": [ [ 845, 856 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033204" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 894, 898 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290403.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 886, 898 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290403.eng.abstr-s1-r1-t3.1-t1.2", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290403.eng.abstr-s7-t3", "arg2_id": "DerOrthopaede.00290403.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOrthopaede.00290403.eng.abstr-s1-r2-t1.2-t1.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290403.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290403.eng.abstr-s7-t1", "normalized": [] }, { "id": "DerOrthopaede.00290403.eng.abstr-s1-r3-t3.1-t1.2", "type": "location_of", "arg1_id": "DerOrthopaede.00290403.eng.abstr-s7-t3", "arg2_id": 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DerOrthopaede.00290411.eng.abstr	DerOrthopaede.00290411.eng.abstr	[ { "id": "DerOrthopaede.00290411.eng.abstr-passage-0", "type": "abstract", "text": [ "There is still controversy whether transient osteoporosis of the hip joint represents a distinct self-limiting disease , or reflects only an early , reversible subtype of non-traumatic osteonecrosis ( ON ) . Transient osteoporosis has several synonyms : algodystrophy of the hip ; transient marrow oedema ; or bone marrow oedema syndrome - BMOES . Clinical presentation of BMOES shows mechanical hip joint pain , ON risk factors , and a diffuse bone marrow oedema in MR imaging . Histomorphological changes resemble early ON , but with diffuse sufficient repair in BMOES and focal and insufficient repair only at the border of the necrotic lesion in ON . Therefore the clinical course and outcome are significant different , with restitution occurring in BMOES , while progressive destruction of the joint takes place in ON . So far , the preferred treatment strategies are protected weight bearing for BMOES , but operative treatment for ON . In a prospective study of patients with BMOES , the clinical , radiographic , and MRI course of 43 hip joints after core decompression treatment were investigated . All patients showed immediate relief of pain after surgery and the average duration of symptoms with conservative treatment could be dramatically reduced by core decompression from 6 months down to 2 months . There were no perioperative complications . Based on our experience with over 100 BMOES patients , we are convinced that this syndrome represents not a distinct disease but an early reversible subtype of non-traumatic ON . Due to the excellent clinical results of core decompression , we recommend this operative therapeutical concept in patients with painful BMOES ." ], "offsets": [ [ 0, 1685 ] ] } ]	[ { "id": "DerOrthopaede.00290411.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "transient" ], "offsets": [ [ 35, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040704" } ] }, { "id": "DerOrthopaede.00290411.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "osteoporosis" ], "offsets": [ [ 45, 57 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029456" } ] }, { "id": "DerOrthopaede.00290411.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 65, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290411.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 69, 74 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290411.eng.abstr-s1-t5", "type": "umlsterm", "text": [ 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DerOrthopaede.00290420.eng.abstr	DerOrthopaede.00290420.eng.abstr	[ { "id": "DerOrthopaede.00290420.eng.abstr-passage-0", "type": "abstract", "text": [ "Core decompression of the necrotic area for treatment of idiopathic osteonecrosis of the femoral head was developed and published by Ficat and Arlet in 1962 within the scope of their \" Functional exploration of bone \" . The mode of action is attributed to a reduction of the intramedullary pressure in the bony compartment of the femoral head . The possibilities of repair and bone regeneration following core decompression are still discussed controversially . Core decompression is a common but not generally accepted procedure in the treatment of idiopathic osteonecrosis of the femoral head . After first publications of positive mid- and long-term effects , some subsequent studies judged it as an ineffective and high-risk method . Analysis of the literature shows that the effectiveness of core decompression depends on the stage of osteonecrosis at the time of surgical intervention . Prognosis is influenced by the extent and location of the necrotic area , the presence and amount of head depression , and continued risk factors - mainly corticoid medication . The best prognosis can be given for patients with a small , medial-centrally located necrosis without head depression ." ], "offsets": [ [ 0, 1190 ] ] } ]	[ { "id": "DerOrthopaede.00290420.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 44, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290420.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 68, 81 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290420.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 97, 101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290420.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 211, 215 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290420.eng.abstr-s1-t5", "type": 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DerOrthopaede.00290430.eng.abstr	DerOrthopaede.00290430.eng.abstr	[ { "id": "DerOrthopaede.00290430.eng.abstr-passage-0", "type": "abstract", "text": [ "The importance of osteotomies in treatment of osteonecrosis of the femoral head has decreased . However , with proper selection of the patient , osteotomies are still useful for small stage III or IV lesions in patients younger than 45 years , and with no ongoing causes for progressive osteonecrosis such as the use of high doses of corticosteroids , chemotherapy , and chronic alcoholism . For preservation of natural hip joint function , the necrotic segment is moved away from the load-transmitting area of the acetabulum , and weight-bearing forces are redistributed to articular cartilage that is supported by healthy bone . In addition to radiographic evaluation , MRI is most accurate for imaging of the stage , localization , and extent of osteonecrosis in planning and selecting osteotomy ." ], "offsets": [ [ 0, 800 ] ] } ]	[ { "id": "DerOrthopaede.00290430.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "osteotomies" ], "offsets": [ [ 18, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029468" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 33, 42 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 46, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 75, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 67, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "selection" ], "offsets": [ [ 118, 127 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036576" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 135, 142 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "osteotomies" ], "offsets": [ [ 145, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029468" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "stage" ], "offsets": [ [ 184, 189 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 211, 219 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "causes" ], "offsets": [ [ 264, 270 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 287, 300 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 313, 316 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "corticosteroids" ], "offsets": [ [ 334, 349 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001617" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "chemotherapy" ], "offsets": [ [ 352, 364 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013216" }, { "db_name": "UMLS", "db_id": "C0013217" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "alcoholism" ], "offsets": [ [ 379, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001973" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s2-t12", "type": "umlsterm", "text": [ "chronic alcoholism" ], "offsets": [ [ 371, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001973" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 420, 423 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 424, 429 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 430, 438 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "acetabulum" ], "offsets": [ [ 515, 525 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000962" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 585, 594 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 624, 628 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "hip joint" ], "offsets": [ [ 420, 429 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019558" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 575, 594 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "evaluation" ], "offsets": [ [ 659, 669 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220825" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "MRI" ], "offsets": [ [ 672, 675 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024485" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "imaging" ], "offsets": [ [ 697, 704 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "stage" ], "offsets": [ [ 712, 717 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 749, 762 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290430.eng.abstr-s4-t6", 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DerOrthopaede.00290442.eng.abstr	DerOrthopaede.00290442.eng.abstr	[ { "id": "DerOrthopaede.00290442.eng.abstr-passage-0", "type": "abstract", "text": [ "Osteonecrosis of the femoral head remains a devastating disease for young patients . As the normal process of bone formation , bone destruction , and fracture healing becomes more clearly understood , molecular agents - including cytokines , bone morphogenetic proteins , and angiogenic factors - will be identified as potential therapeutic agents for the treatment of osteonecrosis . As the pathology of osteonecrosis and repair of osteonecrotic lesions becomes clear , the potential combination of these molecular factors to influence the outcome of the disease in its repair process should become evident ." ], "offsets": [ [ 0, 609 ] ] } ]	[ { "id": "DerOrthopaede.00290442.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Osteonecrosis" ], "offsets": [ [ 0, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" }, { "db_name": "UMLS", "db_id": "C0027543" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 29, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 56, 63 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 74, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 21, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 110, 114 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 127, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "fracture" ], "offsets": [ [ 150, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "cytokines" ], "offsets": [ [ 230, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079189" } ] }, { "id": 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"DerOrthopaede.00290442.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "bone formation" ], "offsets": [ [ 110, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005939" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "angiogenic factors" ], "offsets": [ [ 276, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002976" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t12", "type": "umlsterm", "text": [ "bone morphogenetic proteins" ], "offsets": [ [ 242, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0053932" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "pathology" ], "offsets": [ [ 392, 401 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 405, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": 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DerOrthopaede.00290449.eng.abstr	DerOrthopaede.00290449.eng.abstr	[ { "id": "DerOrthopaede.00290449.eng.abstr-passage-0", "type": "abstract", "text": [ "In literature , the results of hip arthroplasty in patients with avascular osteonecrosis of the femoral head vary . The main reason may be the nonhomogeneous patient groups concerning etiology of the femoral head necrosis ( FHN ) . Analyzing the results of hip endoprosthesis in relation to the etiology of FHN leads to the assumption that steroid-induced FHN and FHN with underlying systemic bone diseases ( renal osteodystrophy , sickle-cell hemoglobinopathy ) have the highest loosening rates . Diseases with immunosuppressive medication and sickle-cell hemoglobinopathy have the highest risk of joint infection . Therefore etiology plays an important role in the long-term results of hip endoprostheses in FHN . Modern cement techniques of the second generation and new non-cemented total hip endoprostheses seem to have better results than older prostheses and cement techniques . We followed-up 52 non-cemented thrust plate prostheses in 45 patients with FHN , prospectively , for at least 2 years ( 3.7 +/- 1.6 years ) . The revision rate was 9.6 % ( two aseptic loosenings in one patient with renal osteodystrophy and one patient with alcohol abuse , as well as three late infections in one patient with alcohol abuse and two patients with renal osteodystrophy ) . Additionally , five prostheses showed radiologic lines of a minimum of 2 mm . Future studies with longer follow-up are needed to find out whether these prosthetic designs with proximal fixation of the femoral component preserving the diaphysial bone have advantages in young FHN patients ." ], "offsets": [ [ 0, 1562 ] ] } ]	[ { "id": "DerOrthopaede.00290449.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 3, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerOrthopaede.00290449.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 31, 34 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290449.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "arthroplasty" ], "offsets": [ [ 35, 47 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003893" } ] }, { "id": "DerOrthopaede.00290449.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 51, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": 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DerOrthopaede.00290457.eng.abstr	DerOrthopaede.00290457.eng.abstr	[ { "id": "DerOrthopaede.00290457.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of osteonecrosis of the femoral head involves a continuum based on a radiographic spectrum of disease . Core decompression or pharmacological agents can be utilized for the earliest small or medium-sized pre-collapsed lesions . For these types of lesions , osteotomy has been tried by various authors with moderate success . For small or medium lesions that are post-collapse , various bone grafting procedures have been used . This approach should be tempered with a look at the articular cartilage if this is damaged or the lesion is large . Limited femoral resurfacing can be used for hips that do not have acetabular involvement . If there is acetabular involvement , total hip replacement remains the treatment of choice ." ], "offsets": [ [ 0, 741 ] ] } ]	[ { "id": "DerOrthopaede.00290457.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 4, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 17, 30 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 46, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 108, 115 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 38, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "osteotomy" ], "offsets": [ [ 271, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029468" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 400, 404 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "grafting" ], "offsets": [ [ 405, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 414, 424 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "bone grafting" ], "offsets": [ [ 400, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005976" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "cartilage" ], "offsets": [ [ 504, 513 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007301" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 494, 513 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "hips" ], "offsets": [ [ 602, 606 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 692, 695 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 720, 729 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "choice" ], "offsets": [ [ 733, 739 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008300" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "hip replacement" ], "offsets": [ [ 692, 707 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0392806" } ] }, { "id": "DerOrthopaede.00290457.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "total hip replacement" ], "offsets": [ [ 686, 707 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040508" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290457.eng.abstr-s1-r1-t4.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290457.eng.abstr-s7-t4", "arg2_id": "DerOrthopaede.00290457.eng.abstr-s7-t1", "normalized": [] }, { "id": "DerOrthopaede.00290457.eng.abstr-s1-r2-t3.1-t5.1", "type": 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DerOrthopaede.00290490.eng.abstr	DerOrthopaede.00290490.eng.abstr	[ { "id": "DerOrthopaede.00290490.eng.abstr-passage-0", "type": "abstract", "text": [ "It is generally accepted that the progression of an idiopathic scoliotic deformity with a Cobb angle of between 25 ° and 40 ° can be stopped by brace treatment alone provided that the generally acknowledged criteria for the treatment concerning skeletal growth of the individual are respected ." ], "offsets": [ [ 0, 294 ] ] } ]	[ { "id": "DerOrthopaede.00290490.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 73, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 150, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "criteria" ], "offsets": [ [ 207, 215 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243161" } ] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 224, 233 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 254, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290490.eng.abstr-s1-r1-t3.1-t4.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r2-t2.1-t4.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r3-t3.1-t2.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r4-t2.1-t1.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r5-t1.1-t4.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r6-t1.1-t2.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOrthopaede.00290490.eng.abstr-s1-r7-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290490.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290490.eng.abstr-s1-t2", "normalized": [] } ]
DerOrthopaede.00290500.eng.abstr	DerOrthopaede.00290500.eng.abstr	[ { "id": "DerOrthopaede.00290500.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of idiopathic scoliosis over 40 ° ( Cobb ) during the growth period is under discussion concerning the indication for conservative or surgical treatment . Curve progression depends on the degree of the frontal and sagittal deformity , vertebral rotation , rigidity of the curve , the skeletal age , the age and sex of the patient , the familial frequency of scoliosis and the location of the curve . In scoliosis over 40 ° progression is fast and the possibilities for successful conservative brace treatment are reduced during the growth period . Progression occurs more frequently in thoracic and double major scolioses , especially in young patients ( Risser sign 0 and 1 ) ." ], "offsets": [ [ 0, 692 ] ] } ]	[ { "id": "DerOrthopaede.00290500.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 4, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 28, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 68, 74 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 75, 81 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 148, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 157, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "surgical treatment" ], "offsets": [ [ 148, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 237, 246 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "rotation" ], "offsets": [ [ 259, 267 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "rigidity" ], "offsets": [ [ 270, 278 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026837" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "age" ], "offsets": [ [ 307, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "age" ], "offsets": [ [ 317, 320 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "sex" ], "offsets": [ [ 325, 328 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079399" }, { "db_name": "UMLS", "db_id": "C0009253" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 336, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 359, 368 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 372, 381 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 417, 426 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 513, 522 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 546, 552 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 553, 559 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "scolioses" ], "offsets": [ [ 626, 635 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 658, 666 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "sign" ], "offsets": [ [ 676, 680 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220912" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290500.eng.abstr-s1-r1-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290500.eng.abstr-s4-t1", 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DerOrthopaede.00290507.eng.abstr	DerOrthopaede.00290507.eng.abstr	[ { "id": "DerOrthopaede.00290507.eng.abstr-passage-0", "type": "abstract", "text": [ "Scoliosis is a complex deformity of the spine with an abnormal shape in all different planes . Purpose of the study is to describe different biomechanical aspects of the operative treatment on the basis of own experimental results and of a review of the literature . The corrective loads , the resistance of the curvature , principles of different implants , the stability of the instrumented spine and problems of implant fixation are discussed . Corrective loads are divided in forces of distraction , compression , translation and rotation . Distraction is more beneficial for severe curvatures ( > 50 ° ) , while transverse load is ideal for milder deformities ( 50 ° ) . Compression is only efficient when applied segmental and anterior . Resistance increases with increasing of the curvature due to the deformation of vertebral bodies . Release is possible anteriorly by open technique or endoscopically and posteriorly by concave thoracoplasty . Principles of different implants are shown : Harrington- ( distraction ) , Luque- ( translation ) , VDS- ( compression , rotation ) , CD- ( combined loading - posterior ) and Kaneda-System ( combined loading - anterior ) . It is possible to perform a primary stable fusion of the spine anterior and posterior . The stability provided by three anterior devices ( VDS , TSRH , CDH ) has been studied in an in-vitro model . TSRH was found to be significantly ( p 0.05 ) higher in stiffness in flexion/extension and torsion than VDS . In bending there was no statistical difference . In all tests CDH was significantly more stable than VDS . In flexion/extension it proved higher in stiffness than TSRH , no statistical difference was observed in bending and rotation . Bone density plays a crucial role in implantfixation , this is more important anterior than posterior . Pedicular screws are superior in their fixational strength than lamina hooks and screws in the vertebral body ." ], "offsets": [ [ 0, 1934 ] ] } ]	[ { "id": "DerOrthopaede.00290507.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Scoliosis" ], "offsets": [ [ 0, 9 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 23, 32 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 40, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 180, 189 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": 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"text": [ "rotation" ], "offsets": [ [ 534, 542 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 653, 664 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 733, 741 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "Release" ], "offsets": [ [ 843, 850 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "open" ], "offsets": [ [ 877, 881 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0266061" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "technique" 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"DerOrthopaede.00290507.eng.abstr-s16-t2", "type": "umlsterm", "text": [ "role" ], "offsets": [ [ 1748, 1752 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035820" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t3", "type": "umlsterm", "text": [ "implantfixation" ], "offsets": [ [ 1756, 1771 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021533" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t4", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 1797, 1805 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t5", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 1811, 1820 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t6", "type": "umlsterm", "text": [ "Bone density" ], "offsets": [ [ 1719, 1731 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005938" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 1833, 1839 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "type": "umlsterm", "text": [ "lamina" ], "offsets": [ [ 1887, 1893 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0064635" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 1904, 1910 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290507.eng.abstr-s1-r1-t2.1-t1.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s1-r2-t1.1-t2.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s1-r3-t3.1-t1.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s1-r4-t3.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-r1-t1.1-t2.1", "type": "affects", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-r2-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-r3-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-r1-t3.1-t5.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s16-t5", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-r2-t3.1-t4.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s16-t4", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-r3-t6.1-t3.1", "type": "measurement_of", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s16-t6", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "normalized": [] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-r4-t3.1-t1.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "arg2_id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "normalized": [] } ]
DerOrthopaede.00290518.eng.abstr	DerOrthopaede.00290518.eng.abstr	[ { "id": "DerOrthopaede.00290518.eng.abstr-passage-0", "type": "abstract", "text": [ "The therapy of neuromuscular scolioses has to be tailored to the needs of the individual patient ; there are no universally valid schemes of treatment . Detailed knowledge of neuromuscular diseases and their course is essential ." ], "offsets": [ [ 0, 229 ] ] } ]	[ { "id": "DerOrthopaede.00290518.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 4, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "scolioses" ], "offsets": [ [ 29, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "needs" ], "offsets": [ [ 65, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027552" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 89, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 141, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 162, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 189, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "neuromuscular diseases" ], "offsets": [ [ 175, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027868" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290518.eng.abstr-s1-r1-t1.1-t3.1", "type": "occurs_in", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r2-t3.1-t5.1", "type": "performs", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r3-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r4-t5.1-t3.1", "type": "affects", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r5-t3.1-t5.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r6-t3.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r7-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s1-t5", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r8-t3.1-t1.1", "type": "performs", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290518.eng.abstr-s1-r9-t1.1-t3.1", "type": "affects", "arg1_id": "DerOrthopaede.00290518.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290518.eng.abstr-s2-t3", "normalized": [] } ]
DerOrthopaede.00290524.eng.abstr	DerOrthopaede.00290524.eng.abstr	[ { "id": "DerOrthopaede.00290524.eng.abstr-passage-0", "type": "abstract", "text": [ "Spine deformities are a frequent symptom of neurofibromatosis Recklinghausen . Especially NF1 shows next to numerous alterations in the skeleton in some cases massive scoliosis and kyphosis . There are different theories for the development of the spine deformities , one of them is that specific alterations of the vertebra are caused by an elevated intraspinal pressure on the osteoporotic bone . A classification from a clinical point of view discriminates 3 types of severity . Type 1 shows instead of the in x-rays inconspicuous findings neurofibromatosistypical alterations in other diagnostic procedures ( e . g . MRI ) . Extreme variations like short curved scoliokyphosis with massive destruction and severe spine imbalance are described as type 3. Operative treatment is dependent on the severity of the deformity . Intraspinal tumors have to be removed . Because of the elevated neurological risk the proceeding has to be very careful , sometimes there is a temporary Halo-extension necessary . Anterior substance defects are filled with bone or cages . The posterior instrumentation ( in most of the cases a 2-rod-stabilization) is performed by transpedicular screws . Frequently there is a concave chest wall plastic ( CTP ) indicated . To prevent neurological complications early surgical procedure is sometimes necessary . Complications can be reduced by careful proceeding , exact preoperative diagnostic and classification . But next to operative experience a qualified anaesthesiological and intensive care units are absolutely necessary ." ], "offsets": [ [ 0, 1557 ] ] } ]	[ { "id": "DerOrthopaede.00290524.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Spine" ], "offsets": [ [ 0, 5 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 6, 17 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "symptom" ], "offsets": [ [ 33, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "neurofibromatosis" ], "offsets": [ [ 44, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162678" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "NF1" ], "offsets": [ [ 90, 93 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085113" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "skeleton" ], "offsets": [ [ 136, 144 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037253" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 167, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "kyphosis" ], "offsets": [ [ 181, 189 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022821" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 229, 240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 248, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 254, 265 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "vertebra" ], "offsets": [ [ 316, 324 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0549207" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "pressure" ], "offsets": [ [ 363, 371 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033095" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 392, 396 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290524.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "classification" ], 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DerOrthopaede.00290535.eng.abstr	DerOrthopaede.00290535.eng.abstr	[ { "id": "DerOrthopaede.00290535.eng.abstr-passage-0", "type": "abstract", "text": [ "We report on three years of experience with a new method of a simultaneous endoscopically assisted anterior release in the prone position , combined with transpedicular posterior scoliosis correction and fixation . In 60 cases this simultaneous approach yielded substantial advantages . True derotation of the apex - even in the thoracic spine - is achieved ." ], "offsets": [ [ 0, 359 ] ] } ]	[ { "id": "DerOrthopaede.00290535.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 50, 56 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 99, 107 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "release" ], "offsets": [ [ 108, 115 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 169, 178 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 179, 188 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "prone position" ], "offsets": [ [ 123, 137 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033422" } ] }, { "id": "DerOrthopaede.00290535.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 338, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290535.eng.abstr-s1-r1-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s3-t1", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-r2-t1.2-t5.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-r3-t3.1-t5.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-r4-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-r5-t1.2-t3.1", "type": "produces", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOrthopaede.00290535.eng.abstr-s1-r6-t3.1-t5.1", "type": "causes", "arg1_id": "DerOrthopaede.00290535.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290535.eng.abstr-s1-t5", "normalized": [] } ]
DerOrthopaede.00290543.eng.abstr	DerOrthopaede.00290543.eng.abstr	[ { "id": "DerOrthopaede.00290543.eng.abstr-passage-0", "type": "abstract", "text": [ "The age of standardized instrumented scoliosis correction and stabilization began with Harrington instrumentation ( HI ) . With HI , satisfactory long-term correction of the frontal plane averaged approximately 50 % , but without notable derotational capabilities . The distraction of the concavity leads to reduction of the sagittal contour of the spine ( flat back ) , which is biomechanically disadvantageous . The newer multisegmentally attached implant systems avoid this disadvantage . The first prototypes of these systems were Luque- ( SSI ) and Cotrel-Dubousset instrumentation . Ideal indications for posterior instrumented curve correction are structural idiopathic double major curves and flexible single curves . However , even with these newer doublerod systems derotation is low , because derotation is , without any doubt , related to anterior release and thus decoupling of the segments by means of disc resection ." ], "offsets": [ [ 0, 932 ] ] } ]	[ { "id": "DerOrthopaede.00290543.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "age" ], "offsets": [ [ 4, 7 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 37, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "instrumentation" ], "offsets": [ [ 98, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021632" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "contour" ], "offsets": [ [ 334, 341 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0302821" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 349, 354 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "instrumentation" ], "offsets": [ [ 571, 586 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021632" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 611, 620 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "single" ], "offsets": [ [ 710, 716 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087136" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "doublerod" ], "offsets": [ [ 758, 767 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206427" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 851, 859 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "release" ], "offsets": [ [ 860, 867 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290543.eng.abstr-s1-r1-t1.2-t1.1", "type": "produces", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-r2-t2.1-t1.1", "type": "occurs_in", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-r3-t3.1-t1.2", "type": "measurement_of", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t3", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-r4-t1.2-t2.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s1-r5-t2.1-t1.2", "type": "result_of", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-r1-t2.1-t3.1", "type": "produces", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t3", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-r2-t2.1-t1.1", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-r3-t1.1-t3.1", "type": "produces", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t3", "normalized": [] }, { "id": "DerOrthopaede.00290543.eng.abstr-s7-r4-t1.1-t2.1", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290543.eng.abstr-s7-t1", "arg2_id": "DerOrthopaede.00290543.eng.abstr-s7-t2", "normalized": [] } ]
DerOrthopaede.00290563.eng.abstr	DerOrthopaede.00290563.eng.abstr	[ { "id": "DerOrthopaede.00290563.eng.abstr-passage-0", "type": "abstract", "text": [ "Halm-Zielke Instrumentation ( HZI ) was developed to eliminate the disadvantage of ventral derotation spondylodesis ( VDS ) - Zielke in terms of lack of primary stability and in order to simplify sagittal plane control . Within a prospective clinical trial started in 1993 , we have studied whether HZI fulfills these demands ." ], "offsets": [ [ 0, 327 ] ] } ]	[ { "id": "DerOrthopaede.00290563.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Instrumentation" ], "offsets": [ [ 12, 27 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021632" } ] }, { "id": "DerOrthopaede.00290563.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "spondylodesis" ], "offsets": [ [ 102, 115 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600339" } ] }, { "id": "DerOrthopaede.00290563.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 211, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "DerOrthopaede.00290563.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "clinical trial" ], "offsets": [ [ 242, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008976" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290563.eng.abstr-s1-r1-t1.1-t2.1", "type": "conceptual_part_of", "arg1_id": "DerOrthopaede.00290563.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290563.eng.abstr-s1-t2", "normalized": [] } ]
DerOrthopaede.00290571.eng.abstr	DerOrthopaede.00290571.eng.abstr	[ { "id": "DerOrthopaede.00290571.eng.abstr-passage-0", "type": "abstract", "text": [ "A number of different procedures are used for the surgical treatment of King II scoliosis . One reason for the controversial discussion in this context is that the term King II scoliosis is usually inadequate , because there are partly marked clinical and radiological differences in this type of curvature ." ], "offsets": [ [ 0, 308 ] ] } ]	[ { "id": "DerOrthopaede.00290571.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 22, 32 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 50, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 59, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 80, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "surgical treatment" ], "offsets": [ [ 50, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" } ] }, { "id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "scoliosis" ], "offsets": [ [ 177, 186 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036439" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290571.eng.abstr-s1-r1-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-r2-t1.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-r3-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s1-t5", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-r4-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-r5-t1.1-t5.1", "type": "conceptual_part_of", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290571.eng.abstr-s1-r6-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290571.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290571.eng.abstr-s2-t1", "normalized": [] } ]
DerOrthopaede.00290605.eng.abstr	DerOrthopaede.00290605.eng.abstr	[ { "id": "DerOrthopaede.00290605.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of the present study was to increase the free range of motion in conventional trust-plate prosthesis design and to optimize the trust-plate contact as well as the osteointegration area below the trust-plate ." ], "offsets": [ [ 0, 220 ] ] } ]	[ { "id": "DerOrthopaede.00290605.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "motion" ], "offsets": [ [ 67, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026597" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "trust-plate" ], "offsets": [ [ 90, 101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005971" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "prosthesis" ], "offsets": [ [ 102, 112 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0525024" }, { "db_name": "UMLS", "db_id": "C0175649" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "trust-plate" ], "offsets": [ [ 140, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005971" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "trust-plate" ], "offsets": [ [ 207, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005971" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "prosthesis design" ], "offsets": [ [ 102, 119 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033585" } ] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "range of motion" ], "offsets": [ [ 58, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080078" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290605.eng.abstr-s1-r1-t7.1-t1.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t7", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r3-t3.1-t6.1", "type": "isa", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r4-t1.1-t7.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t1", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r5-t3.1-t7.1", "type": "affects", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r6-t3.1-t5.1", "type": "uses", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r7-t6.1-t7.1", "type": "affects", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t6", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOrthopaede.00290605.eng.abstr-s1-r8-t3.1-t2.1", "type": "uses", "arg1_id": "DerOrthopaede.00290605.eng.abstr-s1-t3", "arg2_id": "DerOrthopaede.00290605.eng.abstr-s1-t2", "normalized": [] } ]
DerOrthopaede.00290614.eng.abstr	DerOrthopaede.00290614.eng.abstr	[ { "id": "DerOrthopaede.00290614.eng.abstr-passage-0", "type": "abstract", "text": [ "Modern approaches in knee endoprosthetics using computer-assisted navigation systems are based on matching procedures which refer to osseous anatomical landmarks . However , surface replacement techniques require a correct position of the implants in relation to the bone , as well as an optimal postoperative interaction of the ligaments and the surface design of the endoprosthesis . Functional aspects are of elementary importance ." ], "offsets": [ [ 0, 435 ] ] } ]	[ { "id": "DerOrthopaede.00290614.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "knee" ], "offsets": [ [ 21, 25 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022742" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 107, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "anatomical" ], "offsets": [ [ 141, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 194, 204 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 267, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 296, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "interaction" ], "offsets": [ [ 310, 321 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037420" } ] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "ligaments" ], "offsets": [ [ 329, 338 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023685" }, { "db_name": "UMLS", "db_id": "C0023686" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290614.eng.abstr-s1-r1-t2.1-t1.1", "type": "measurement_of", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t2", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r1-t4.1-t1.1", "type": "developmental_form_of", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r2-t4.1-t5.2", "type": "developmental_form_of", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r3-t2.1-t4.1", "type": "surrounds", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t2", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r4-t4.1-t2.1", "type": "developmental_form_of", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r5-t5.2-t4.1", "type": "surrounds", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t5", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOrthopaede.00290614.eng.abstr-s2-r6-t1.1-t4.1", "type": "surrounds", "arg1_id": "DerOrthopaede.00290614.eng.abstr-s2-t1", "arg2_id": "DerOrthopaede.00290614.eng.abstr-s2-t4", "normalized": [] } ]
DerOrthopaede.00290627.eng.abstr	DerOrthopaede.00290627.eng.abstr	[ { "id": "DerOrthopaede.00290627.eng.abstr-passage-0", "type": "abstract", "text": [ "Using CT-based 3D-data of human femora , it is possible to simulate the THR very realistically by a newly developed fit program . The evaluation of OP simulations of different prostheses systems on more than 200 femora showed that a large number of hip joints can only be reconstructed unsatisfactorily by standard stems regarding intramedullary fit and joint geometry . This could be minimized by optimized off-the-shelf prostheses , but there is still a remainder that can only be satisfactorily reconstructed by customized devices . The decision of choosing a standard or custom device for each individual case can be made by the same fit program using CT-data of the femur . Planning with conventional X-rays only shows major restrictions ." ], "offsets": [ [ 0, 744 ] ] } ]	[ { "id": "DerOrthopaede.00290627.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 26, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "femora" ], "offsets": [ [ 32, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015811" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "fit" ], "offsets": [ [ 116, 119 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036572" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "program" ], "offsets": [ [ 120, 127 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376691" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "evaluation" ], "offsets": [ [ 134, 144 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220825" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "prostheses" ], "offsets": [ [ 176, 186 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0525024" }, { "db_name": "UMLS", "db_id": "C0175649" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "femora" ], "offsets": [ [ 212, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015811" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "hip" ], "offsets": [ [ 249, 252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019552" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "joints" ], "offsets": [ [ 253, 259 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "standard" ], "offsets": [ [ 306, 314 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038137" }, { "db_name": "UMLS", "db_id": "C0175675" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "fit" ], "offsets": [ [ 346, 349 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036572" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 354, 359 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "hip joints" ], "offsets": [ [ 249, 259 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019558" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "prostheses" ], "offsets": [ [ 422, 432 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0525024" }, { "db_name": "UMLS", "db_id": "C0175649" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "devices" ], "offsets": [ [ 526, 533 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "standard" ], "offsets": [ [ 563, 571 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038137" }, { "db_name": "UMLS", "db_id": "C0175675" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "custom" ], "offsets": [ [ 575, 581 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162343" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "device" ], "offsets": [ [ 582, 588 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "fit" ], "offsets": [ [ 638, 641 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036572" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "program" ], "offsets": [ [ 642, 649 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376691" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "femur" ], "offsets": [ [ 671, 676 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015811" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Planning" ], "offsets": [ [ 679, 687 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "X-rays" ], "offsets": [ [ 706, 712 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043309" } ] } ]	[]	[]	[ { "id": "DerOrthopaede.00290627.eng.abstr-s2-r1-t6.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t6", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-r2-t2.2-t9.1", "type": "interconnects", "arg1_id": 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"DerOrthopaede.00290627.eng.abstr-s2-r21-t6.2-t1.1", "type": "evaluation_of", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s2-t6", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-r22-t2.2-t4.1", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s3-t2", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-r23-t5.1-t4.1", "type": "adjacent_to", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t5", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s2-r24-t9.1-t1.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s2-t9", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s3-r1-t1.2-t2.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s3-r2-t1.1-t1.2", "type": "uses", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s3-r3-t1.1-t2.1", "type": "uses", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-r1-t3.2-t2.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-r2-t1.2-t1.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-r3-t1.2-t2.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-r4-t1.1-t2.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t2", "normalized": [] }, { "id": "DerOrthopaede.00290627.eng.abstr-s4-r5-t3.2-t1.1", "type": "isa", "arg1_id": "DerOrthopaede.00290627.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290627.eng.abstr-s5-t1", "normalized": [] } ]

DerOpthalmologe.90960410.eng.abstr

[ { "id": "DerOpthalmologe.90960410.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Incarceration of the iris is a potential complication following trabeculectomy in primary congenital glaucoma . Although this complication is mentioned in the literature , nothing is reported about the technique of surgical revision ." ], "offsets": [ [ 0, 247 ] ] } ]

[ { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "iris" ], "offsets": [ [ 34, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022077" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "complication" ], "offsets": [ [ 54, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "trabeculectomy" ], "offsets": [ [ 77, 91 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040574" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "congenital" ], "offsets": [ [ 103, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009678" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 114, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "congenital glaucoma" ], "offsets": [ [ 103, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020302" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "complication" ], "offsets": [ [ 139, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 172, 182 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 215, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 228, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960410.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "surgical revision" ], "offsets": [ [ 228, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035110" } ] } ]

[]

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DerOpthalmologe.90960421.eng.abstr

[ { "id": "DerOpthalmologe.90960421.eng.abstr-passage-0", "type": "abstract", "text": [ "The follow-up of central scotomas and fixation - next to visual acuity - are important parameters for the evaluation of new therapies in AMD ." ], "offsets": [ [ 0, 142 ] ] } ]

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[]

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DerOpthalmologe.90960428.eng.abstr

[ { "id": "DerOpthalmologe.90960428.eng.abstr-passage-0", "type": "abstract", "text": [ "The accuracy of the spectrometric measurement of the oxygen saturation in retinal vessels is limited by its signal-to-noise ratio . The aim of this study was to investigate the possibility of enhancement of the reflection signal by the use of polarized light ." ], "offsets": [ [ 0, 260 ] ] } ]

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[]

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DerOpthalmologe.90960432.eng.abstr

[ { "id": "DerOpthalmologe.90960432.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : To prevent surgically induced astigmatism following clear corneal cataract surgery ." ], "offsets": [ [ 0, 97 ] ] } ]

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[]

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DerOpthalmologe.90960437.eng.abstr

[ { "id": "DerOpthalmologe.90960437.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : The first morphological changes in eyes with HIV infection are microvascular disease of the retina with cotton-wool spots and microaneurysms . The study was performed to find out if evidence of disturbances of ocular microcirculation can be established by non-invasive methods ." ], "offsets": [ [ 0, 288 ] ] } ]

[ { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "morphological" ], "offsets": [ [ 20, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543482" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 45, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "HIV" ], "offsets": [ [ 55, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019682" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 59, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 87, 94 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "retina" ], "offsets": [ [ 102, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035298" }, { "db_name": "UMLS", "db_id": "C0035309" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "spots" ], "offsets": [ [ 126, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015230" }, { "db_name": "UMLS", "db_id": "C0312414" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "HIV infection" ], "offsets": [ [ 55, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019693" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "microcirculation" ], "offsets": [ [ 227, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025962" } ] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 279, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] } ]

[]

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"arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r22-t6.1-t2.3", "type": "part_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r23-t7.2-t2.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r24-t1.1-t6.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r25-t2.2-t2.3", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r26-t2.3-t6.2", 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"normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r31-t2.2-t7.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r33-t2.2-t4.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r34-t7.2-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r35-t2.2-t5.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r36-t7.2-t4.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r37-t2.2-t7.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r38-t6.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r39-t7.2-t2.3", "type": "affects", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r40-t7.2-t6.2", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r41-t6.1-t4.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r42-t1.1-t2.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r43-t2.3-t7.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r44-t2.2-t6.2", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r45-t1.1-t2.2", "type": "part_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": 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"associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r52-t2.2-t6.2", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r53-t7.2-t6.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s1-r54-t2.3-t7.1", "type": "causes", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s1-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-r1-t2.1-t1.1", "type": "measurement_of", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960437.eng.abstr-s2-r2-t1.1-t2.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960437.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960437.eng.abstr-s2-t2", "normalized": [] } ]

DerOpthalmologe.90960443.eng.abstr

[ { "id": "DerOpthalmologe.90960443.eng.abstr-passage-0", "type": "abstract", "text": [ "Failures with external DCR have also been attributed to canalicular occlusion . Since 1976 we have documented all patients with surgical reconstruction of occluded canaliculi . The indication , different surgical methods of choice and functional prognosis were evaluated ." ], "offsets": [ [ 0, 272 ] ] } ]

[ { "id": "DerOpthalmologe.90960443.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "DCR" ], "offsets": [ [ 23, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010931" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 114, 122 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 128, 136 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "surgical reconstruction" ], "offsets": [ [ 128, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524865" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 204, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 213, 220 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "choice" ], "offsets": [ [ 224, 230 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008300" } ] }, { "id": "DerOpthalmologe.90960443.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "prognosis" ], "offsets": [ [ 246, 255 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033325" } ] } ]

[]

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DerOpthalmologe.90960448.eng.abstr

[ { "id": "DerOpthalmologe.90960448.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : After treatment of anterior chamber fibrinous reactions by tissue plasminogen activator ( TPA ) , irreversible corneal opacifications ( calcium phosphate ) have been observed . To understand the mechanism of these opacifications an animal model was developed ." ], "offsets": [ [ 0, 273 ] ] } ]

[ { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 19, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 32, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 72, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "plasminogen" ], "offsets": [ [ 79, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032140" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "TPA" ], "offsets": [ [ 103, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076729" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "calcium" ], "offsets": [ [ 149, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006675" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "phosphate" ], "offsets": [ [ 157, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031603" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "After treatment" ], "offsets": [ [ 13, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001758" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "anterior chamber" ], "offsets": [ [ 32, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003151" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "plasminogen activator" ], "offsets": [ [ 79, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032144" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "calcium phosphate" ], "offsets": [ [ 149, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006711" }, { "db_name": "UMLS", "db_id": "C0006712" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "tissue plasminogen activator" ], "offsets": [ [ 72, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032143" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "animal" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003043" }, { "db_name": "UMLS", "db_id": "C0003062" } ] }, { "id": "DerOpthalmologe.90960448.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "animal model" ], "offsets": [ [ 245, 257 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0599779" } ] } ]

[]

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DerOpthalmologe.90960453.eng.abstr

[ { "id": "DerOpthalmologe.90960453.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : The correction of low to moderate astigmatism is possible today by means of photoablation ( PRK ) , while the treatment of moderate and higher astigmatism still involves refractive keratotomy . Experience has shown that cataract surgery , using modern tunnel techniques with self-healing incisions , results in earlier stability in both the refractive outcome and wound healing . In this study , we attempted to combine the advantages of lamellar keratotomy with those of a pair-wise T-incision as arcuate lamellar keratotomy ( ALK ) ." ], "offsets": [ [ 0, 550 ] ] } ]

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[]

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DerOpthalmologe.90960470.eng.abstr

[ { "id": "DerOpthalmologe.90960470.eng.abstr-passage-0", "type": "abstract", "text": [ "The presence of ophthalmological journals in the WWW is already very extensive . However , the online presence of these journals and publishing houses are qualitatively and quantitatively very different . Online publications offer many advantages in contrast to conventional publications , as for example low manufacture-expenses and speedy , place- and time-independent availability of information . We assume , that online publications will not replace printpublications , but represents a meaningful supplement of the previous offer of information ." ], "offsets": [ [ 0, 552 ] ] } ]

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DerOpthalmologe.90960489.eng.abstr

[ { "id": "DerOpthalmologe.90960489.eng.abstr-passage-0", "type": "abstract", "text": [ "In recent years good results after treatment of different superficial corneal pathologies with the excimer laser 193 nm have been reported . Thiel-Behnke dystrophy is a hereditary form of anterior stromal dystrophy , a promising layer for successful phototherapeutic keratectomy ( PTK ) . This type of dystrophy was first described in 1967 in Kiel ." ], "offsets": [ [ 0, 349 ] ] } ]

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DerOpthalmologe.90960494.eng.abstr

[ { "id": "DerOpthalmologe.90960494.eng.abstr-passage-0", "type": "abstract", "text": [ "Lid-loading with precious metals , described by Illig in 1958 , has become increasingly important . Because of its good functional and cosmetic results this method is superior to tarsorrhaphy . Furthermore , lid-loading can be combined with additional surgical techniques to achieve more dynamic lid-closure . In a prospective study we examined the results after lid-loading and discuss postoperative changes of the cornea ." ], "offsets": [ [ 0, 424 ] ] } ]

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DerOpthalmologe.90960498.eng.abstr

[ { "id": "DerOpthalmologe.90960498.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Applanation tonometry in eyes with pathological corneae can often not be performed or delivers rather questionable results . We report on our 4-year experience with electronic intraocular needle tonometry ." ], "offsets": [ [ 0, 219 ] ] } ]

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[]

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DerOpthalmologe.90960503.eng.abstr

[ { "id": "DerOpthalmologe.90960503.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The incidence and course of intraoperative and postoperative complications of LASIK were investigated ." ], "offsets": [ [ 0, 116 ] ] } ]

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[]

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DerOpthalmologe.90960509.eng.abstr

[ { "id": "DerOpthalmologe.90960509.eng.abstr-passage-0", "type": "abstract", "text": [ "The main advantage of the bilateral medial rectus faden operation ( posterior fixation suture ) for the treatment of essential infantile esotropia is the low occurrence of delayed consecutive exotropia . Nevertheless , this unwanted complication also occasionally occurs after a faden operation ." ], "offsets": [ [ 0, 296 ] ] } ]

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[]

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DerOpthalmologe.90960513.eng.abstr

[ { "id": "DerOpthalmologe.90960513.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : In cases of esotropia combined with a high AC/A ratio , partly accommodative convergence excess or with nonaccommodative convergence excess , two methods of surgical therapy are possible : recession of the medial recti ( Parks ) and retroequatorial myopexy ( Cueppers ) . Our aim was to answer the question whether retroequatorial myopexy alone and in combination with bimedial recession are appropriate methods of reducing the strabismic angle at near and distant fixation to values under 10 PD and near-distance disparity to less than 10 PD to form the basis for single binocular vision without bifocals ." ], "offsets": [ [ 0, 617 ] ] } ]

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[]

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"DerOpthalmologe.90960513.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960513.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960513.eng.abstr-s2-r17-t1.1-t7.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960513.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960513.eng.abstr-s2-t7", "normalized": [] } ]

DerOpthalmologe.90960522.eng.abstr

[ { "id": "DerOpthalmologe.90960522.eng.abstr-passage-0", "type": "abstract", "text": [ "Acute syphilitic posterior placoid chorioretinitis ( ASPPC ) has been described as a rare chorioretinal manifestation in patients with secondary syphilis . The fundus changes may simulate other chorioretinal disorders and thus delay an accurate diagnosis and initiation of appropriate pharmacological therapy ." ], "offsets": [ [ 0, 310 ] ] } ]

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[]

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DerOpthalmologe.90960529.eng.abstr

[ { "id": "DerOpthalmologe.90960529.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Isolated trauma of the optic nerve usually occurs in association with blunt skull trauma involving fractures of the skull and optic canal , but rarely occurs from blunt ocular trauma ." ], "offsets": [ [ 0, 199 ] ] } ]

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[]

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DerOpthalmologe.90960570.eng.abstr

[ { "id": "DerOpthalmologe.90960570.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Research into the molecular and genetic basis of disease is continually expanding . How does the increasing knowledge about the genetic basis of eye diseases contribute to the development of new therapeutic strategies ?" ], "offsets": [ [ 0, 232 ] ] } ]

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[]

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DerOpthalmologe.90960578.eng.abstr

[ { "id": "DerOpthalmologe.90960578.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Multifocal intraocular lenses ( MIOLs ) have been implanted with good results for several years . Because the light is distributed between two or more focuses , there is slight light reduction for every picture . Capsular fibrosis can cause additional reduction of the amount of light to the retina ." ], "offsets": [ [ 0, 315 ] ] } ]

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[]

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DerOpthalmologe.90960583.eng.abstr

[ { "id": "DerOpthalmologe.90960583.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : In the present study we evaluated the influence of topical miotics on intraocular pressure and the blood-aqueous barrier after uncomplicated phacoemulsification and PC-IOL implantation ." ], "offsets": [ [ 0, 199 ] ] } ]

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[]

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DerOpthalmologe.90960587.eng.abstr

[ { "id": "DerOpthalmologe.90960587.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : In therapy-resistant fibrin reactions within the anterior chamber , especially following combined cataract and glaucoma surgery , injection of TPA is indicated . We report our results ." ], "offsets": [ [ 0, 198 ] ] } ]

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[]

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"DerOpthalmologe.90960587.eng.abstr-s1-r48-t8.1-t5.1", "type": "indicates", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t8", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r49-t5.1-t6.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r50-t5.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r51-t5.1-t6.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r52-t5.1-t8.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t8", "normalized": [] }, { "id": "DerOpthalmologe.90960587.eng.abstr-s1-r53-t9.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960587.eng.abstr-s1-t9", "arg2_id": "DerOpthalmologe.90960587.eng.abstr-s1-t5", "normalized": [] } ]

DerOpthalmologe.90960594.eng.abstr

[ { "id": "DerOpthalmologe.90960594.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The recently described \" APC resistance \" caused by a mutant form of factor V ( factor V Leiden ) is the most frequent cause of hereditary thrombosis . This study was carried out to investigate the association between activated protein C resistance and central retinal vein occlusion ( CRVO ) . We evaluated the prevalence of APC resistance in patients with CRVO , patients with a history of deep-vein thrombosis , and a healthy control group ." ], "offsets": [ [ 0, 457 ] ] } ]

[ { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "APC" ], "offsets": [ [ 38, 41 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003315" }, { "db_name": "UMLS", "db_id": "C0162832" }, { "db_name": "UMLS", "db_id": "C0033036" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "form" ], "offsets": [ [ 74, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "cause" ], "offsets": [ [ 132, 137 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "thrombosis" ], "offsets": [ [ 152, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040053" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "APC resistance" ], "offsets": [ [ 38, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600433" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "factor V" ], "offsets": [ [ 82, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015498" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "factor V" ], "offsets": [ [ 93, 101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015498" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "factor V Leiden" ], "offsets": [ [ 93, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0380964" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "association" ], "offsets": [ [ 211, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004083" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "protein" ], "offsets": [ [ 241, 248 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "retinal" ], "offsets": [ [ 274, 281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "vein" ], "offsets": [ [ 282, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042449" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "protein C" ], "offsets": [ [ 241, 250 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033621" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "retinal vein" ], "offsets": [ [ 274, 286 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035327" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "retinal vein occlusion" ], "offsets": [ [ 274, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035328" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 325, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "APC" ], "offsets": [ [ 339, 342 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003315" }, { "db_name": "UMLS", "db_id": "C0162832" }, { "db_name": "UMLS", "db_id": "C0033036" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 357, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 378, 386 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "history" ], "offsets": [ [ 394, 401 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019664" }, { "db_name": "UMLS", "db_id": "C0019665" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "deep-vein" ], "offsets": [ [ 405, 414 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042449" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "thrombosis" ], "offsets": [ [ 415, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040053" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 442, 449 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "APC resistance" ], "offsets": [ [ 339, 353 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600433" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t10", "type": "umlsterm", "text": [ "deep-vein thrombosis" ], "offsets": [ [ 405, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0149871" } ] }, { "id": "DerOpthalmologe.90960594.eng.abstr-s3-t11", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 442, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] } ]

[]

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DerOpthalmologe.90960600.eng.abstr

[ { "id": "DerOpthalmologe.90960600.eng.abstr-passage-0", "type": "abstract", "text": [ "In spite of the availability of cyclocryodestructive laser therapy there still appears to be an indication for cyclocryotherapy in different kinds of glaucoma ." ], "offsets": [ [ 0, 160 ] ] } ]

[ { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 53, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 59, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960600.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 150, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] } ]

[]

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DerOpthalmologe.90960605.eng.abstr

[ { "id": "DerOpthalmologe.90960605.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : If the surgeon cannot find the tendon of the superior oblique muscle in the right place , he has to change his operative plans intraoperatively . Different procedures are recommended : reinsertion of the superior oblique in the right place , recession of the inferior oblique muscle , and operations on the vertical muscles of the same or the yoke eye . No quantitative recommendations on the surgical amount are mentioned in the literature ." ], "offsets": [ [ 0, 457 ] ] } ]

[ { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 46, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "muscle" ], "offsets": [ [ 77, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 91, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "plans" ], "offsets": [ [ 136, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 171, 181 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "reinsertion" ], "offsets": [ [ 200, 211 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035139" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 243, 248 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "muscle" ], "offsets": [ [ 291, 297 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "operations" ], "offsets": [ [ 304, 314 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "muscles" ], "offsets": [ [ 331, 338 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026845" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "eye" ], "offsets": [ [ 363, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "recommendations" ], "offsets": [ [ 385, 400 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034866" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 408, 416 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960605.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 445, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] } ]

[]

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DerOpthalmologe.90960611.eng.abstr

[ { "id": "DerOpthalmologe.90960611.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The rehabilitation of low vision patients is of increasing importance since the number of these patients has grown rapidly . We wanted to evaluate the actual spectrum of patients concerning age and diagnoses and the appropriate low vision aids ( LVA ) in 1 year ." ], "offsets": [ [ 0, 276 ] ] } ]

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[]

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DerOpthalmologe.90960640.eng.abstr

[ { "id": "DerOpthalmologe.90960640.eng.abstr-passage-0", "type": "abstract", "text": [ "Backround : Although cataract surgery is highly developed today , there are still problems such as secondary cataract . In polishing the posterior capsule lens , epithelial cells often remain , causing secondary cataracts . Additionally , there are the problems of tissue heating and endothelial cell loss during phacoemulsification by ultrasound . This could be another field for improvement of cataract surgery by using the waterjet ." ], "offsets": [ [ 0, 436 ] ] } ]

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[]

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"DerOpthalmologe.90960640.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s4-r3-t2.2-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960640.eng.abstr-s4-t2", "arg2_id": "DerOpthalmologe.90960640.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960640.eng.abstr-s4-r5-t1.1-t2.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960640.eng.abstr-s4-t1", "arg2_id": "DerOpthalmologe.90960640.eng.abstr-s4-t2", "normalized": [] } ]

DerOpthalmologe.90960648.eng.abstr

[ { "id": "DerOpthalmologe.90960648.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The transplantation of retinal pigment epithelial cells ( RPE ) in patients with age-related macular degeneration is discussed as a future therapy . A cornea bank can serve as a source for cells that can be isolated , cultivated , HLA-typed and cryopreserved for subsequent tissue-compatible transplantation ." ], "offsets": [ [ 0, 322 ] ] } ]

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[]

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"DerOpthalmologe.90960648.eng.abstr-s2-r20-t2.1-t1.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960648.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960648.eng.abstr-s2-t1", "normalized": [] } ]

DerOpthalmologe.90960653.eng.abstr

[ { "id": "DerOpthalmologe.90960653.eng.abstr-passage-0", "type": "abstract", "text": [ "In incurable glaucoma the implantation of traditional drainage systems ( such as the Molteno implant ) usually leads to extreme hypotension in the eye in the first postoperative period . The Ahmed Glaucoma Valve presents an alternative method to avoid this problem ." ], "offsets": [ [ 0, 266 ] ] } ]

[ { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "glaucoma" ], "offsets": [ [ 13, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "implantation" ], "offsets": [ [ 26, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029976" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "drainage" ], "offsets": [ [ 54, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013103" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "hypotension" ], "offsets": [ [ 128, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020649" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "eye" ], "offsets": [ [ 147, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 164, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 178, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "Molteno implant" ], "offsets": [ [ 85, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0181899" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "postoperative period" ], "offsets": [ [ 164, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Glaucoma" ], "offsets": [ [ 197, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017601" } ] }, { "id": "DerOpthalmologe.90960653.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 236, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] } ]

[]

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DerOpthalmologe.90960658.eng.abstr

[ { "id": "DerOpthalmologe.90960658.eng.abstr-passage-0", "type": "abstract", "text": [ "Dacryocystorhinostomy is still the standard procedure complete stenosis of the nasolacrimal duct . New methods try to preserve the natural lacrimal pathway . Song implanted in 1995 a nasolacrimal polyurethane stent through the nasolacrimal duct . The results and complications of this new method are described in this prospective study ." ], "offsets": [ [ 0, 337 ] ] } ]

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[]

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DerOpthalmologe.90960663.eng.abstr

[ { "id": "DerOpthalmologe.90960663.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Most germs causing postoperative endophthalmitis derive from the conjunctival bacterial normal flora . Postoperative endophthalmitis is often induced by staphylococcal germs . The application of polyvidone-iodine solution to the conjunctiva is one possibility to reduce potential endophthalmitis-causing bacteria . The aim of this study was to evaluate the effectiveness of 1 % polyvidone-iodine solution concerning the reduction of colonization with staphylococci in the course of intraocular surgery . This is to evaluate the effectiveness of 1 % polyvidone-iodine solution concerning coagulase-negative and positive staphylococci ." ], "offsets": [ [ 0, 647 ] ] } ]

[ { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 32, 45 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "endophthalmitis" ], "offsets": [ [ 46, 61 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014236" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "bacterial" ], "offsets": [ [ 91, 100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0521009" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Postoperative" ], "offsets": [ [ 116, 129 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "endophthalmitis" ], "offsets": [ [ 130, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014236" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 226, 234 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "conjunctiva" ], "offsets": [ [ 242, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009758" }, { "db_name": "UMLS", "db_id": "C0009759" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "bacteria" ], "offsets": [ [ 317, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004611" }, { "db_name": "UMLS", "db_id": "C0521009" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 332, 335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 409, 417 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "staphylococci" ], "offsets": [ [ 464, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038170" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 507, 514 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 580, 588 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "coagulase-negative" ], "offsets": [ [ 600, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009118" } ] }, { "id": "DerOpthalmologe.90960663.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "staphylococci" ], "offsets": [ [ 632, 645 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038170" } ] } ]

[]

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DerOpthalmologe.90960668.eng.abstr

[ { "id": "DerOpthalmologe.90960668.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : Retinal laser coagulation ( LC ) of extrafoveal subretinal neovascularization ( SRN ) due to age-related macular degeneration ( AMD ) is the only sure therapy . Diagnostics , therapy and follow-up are presented in a case report ." ], "offsets": [ [ 0, 244 ] ] } ]

[ { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Retinal" ], "offsets": [ [ 15, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035331" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 23, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "coagulation" ], "offsets": [ [ 29, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "neovascularization" ], "offsets": [ [ 74, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027686" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 166, 173 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "laser coagulation" ], "offsets": [ [ 23, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086524" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "macular degeneration" ], "offsets": [ [ 120, 140 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024437" }, { "db_name": "UMLS", "db_id": "C0242383" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Diagnostics" ], "offsets": [ [ 176, 187 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 190, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960668.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "case report" ], "offsets": [ [ 231, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007320" } ] } ]

[]

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"arg2_id": "DerOpthalmologe.90960668.eng.abstr-s1-t7", "normalized": [] } ]

DerOpthalmologe.90960673.eng.abstr

[ { "id": "DerOpthalmologe.90960673.eng.abstr-passage-0", "type": "abstract", "text": [ "Persistent defects of the ocular surface remain a therapeutic challenge , which often requires surgical intervention . Recently , transplantation of human amniotic membrane has been suggested for reconstruction of the corneal surface . We describe two techniques using cryo-preserved amniotic membrane . Transplantation of several layers of amniotic membrane can successfully restore deep corneal ulcers associated with persistent epithelial defects . When such defects are not associated with stromal ulcers , they might benefit from amniotic membrane grafts sutured to cover the entire corneal surface . Both methods may serve as valuable tools for ocular surface reconstruction , especially in the context of impaired epithelial function ." ], "offsets": [ [ 0, 742 ] ] } ]

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[]

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"DerOpthalmologe.90960673.eng.abstr-s5-t4", "arg2_id": "DerOpthalmologe.90960673.eng.abstr-s6-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s6-r1-t1.1-t2.1", "type": "measurement_of", "arg1_id": "DerOpthalmologe.90960673.eng.abstr-s6-t1", "arg2_id": "DerOpthalmologe.90960673.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960673.eng.abstr-s6-r2-t2.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960673.eng.abstr-s6-t2", "arg2_id": "DerOpthalmologe.90960673.eng.abstr-s6-t1", "normalized": [] } ]

DerOpthalmologe.90960698.eng.abstr

[ { "id": "DerOpthalmologe.90960698.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Leber's hereditary optic neuropathy is associated with point mutations in the mitochondrial DNA ( mtDNA ) that appear to be pathogenetic for this disease . These mutations affect nucleotide positions 3460 , 11778 and 14484. Does the clinical course of LHON differ between men , women and children ?" ], "offsets": [ [ 0, 311 ] ] } ]

[ { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "optic" ], "offsets": [ [ 32, 37 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029144" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 74, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "DNA" ], "offsets": [ [ 105, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012854" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "mtDNA" ], "offsets": [ [ 111, 116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012929" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 159, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "optic neuropathy" ], "offsets": [ [ 32, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029132" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "point mutations" ], "offsets": [ [ 68, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162735" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "mitochondrial DNA" ], "offsets": [ [ 91, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012929" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 175, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "nucleotide" ], "offsets": [ [ 192, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028630" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "men" ], "offsets": [ [ 285, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025266" }, { "db_name": "UMLS", "db_id": "C0024554" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "women" ], "offsets": [ [ 291, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerOpthalmologe.90960698.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 301, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] } ]

[]

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"DerOpthalmologe.90960698.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960698.eng.abstr-s2-t3", "normalized": [] } ]

DerOpthalmologe.90960706.eng.abstr

[ { "id": "DerOpthalmologe.90960706.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : Most of the antiglaucomatous drugs affect ocular blood flow . Blood flow of the anterior uvea under the effect of glaucoma medication has been described in the literature , but measurement of microcirculation at the posterior pole correlated to glaucoma medication is rarely found . We present a placebo-controlled study in which we focused on the short and long-term effects of topical dipivefrine 0.1 % on the microcirculation of the retina and optic nerve head ." ], "offsets": [ [ 0, 475 ] ] } ]

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[]

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"normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r82-t1.1-t5.1", "type": "result_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r84-t8.3-t7.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r85-t3.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r87-t3.2-t7.1", "type": "degree_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r88-t5.1-t1.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r89-t1.1-t8.3", "type": "affects", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t8", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r90-t9.1-t5.1", "type": "adjacent_to", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r91-t9.1-t5.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t9", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r92-t5.1-t1.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t5", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960706.eng.abstr-s3-r93-t1.1-t3.2", "type": "diagnoses", "arg1_id": "DerOpthalmologe.90960706.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960706.eng.abstr-s3-t3", "normalized": [] } ]

DerOpthalmologe.90960711.eng.abstr

[ { "id": "DerOpthalmologe.90960711.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Data on mesopic vision after LASIK are not available to date . We therefore evaluated mesopic vision in myopic eyes before and after LASIK ." ], "offsets": [ [ 0, 153 ] ] } ]

[ { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 29, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "LASIK" ], "offsets": [ [ 42, 47 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0752094" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "date" ], "offsets": [ [ 69, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011008" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "vision" ], "offsets": [ [ 107, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042789" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 124, 128 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960711.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "LASIK" ], "offsets": [ [ 146, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0752094" } ] } ]

[]

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DerOpthalmologe.90960724.eng.abstr

[ { "id": "DerOpthalmologe.90960724.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Orbitotomies have special place in ophthalmic surgery because of the anatomical structures involved and the variety of perioperative problems . We performed a retrospective analysis of orbitotomies carried out in our department in order to give us some more detailed information about the frequency and extent of the various intra- and postoperative problems of orbital surgery ." ], "offsets": [ [ 0, 392 ] ] } ]

[ { "id": "DerOpthalmologe.90960724.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 59, 66 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "anatomical" ], "offsets": [ [ 82, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "retrospective" ], "offsets": [ [ 172, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 186, 194 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 302, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 349, 362 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 383, 390 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] } ]

[]

[ { "id": "DerOpthalmologe.90960724.eng.abstr-s1-r1-t1.2-t1.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s1-r2-t2.1-t1.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r1-t2.1-t3.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r3-t2.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r4-t2.1-t1.1", "type": "measures", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r5-t2.1-t5.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r6-t3.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t3", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960724.eng.abstr-s2-r7-t1.1-t5.1", "type": "issue_in", "arg1_id": "DerOpthalmologe.90960724.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960724.eng.abstr-s2-t5", "normalized": [] } ]

DerOpthalmologe.90960728.eng.abstr

[ { "id": "DerOpthalmologe.90960728.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : Retrospective study concerning the value of conjunctival biopsy in the diagnosis of sarcoidosis ." ], "offsets": [ [ 0, 107 ] ] } ]

[ { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Retrospective" ], "offsets": [ [ 10, 23 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "value" ], "offsets": [ [ 45, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042295" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "biopsy" ], "offsets": [ [ 67, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 81, 90 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "sarcoidosis" ], "offsets": [ [ 94, 105 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036202" } ] }, { "id": "DerOpthalmologe.90960728.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "Retrospective study" ], "offsets": [ [ 10, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035363" } ] } ]

[]

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DerOpthalmologe.90960731.eng.abstr

[ { "id": "DerOpthalmologe.90960731.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Rarely , an additional Brown's syndrome develops spontaneously in cases of posttraumatic bilateral superior oblique palsy . Surgical measures are controversial and problematic ." ], "offsets": [ [ 0, 190 ] ] } ]

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[]

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DerOpthalmologe.90960736.eng.abstr

[ { "id": "DerOpthalmologe.90960736.eng.abstr-passage-0", "type": "abstract", "text": [ "There is no generally accepted therapy for patients with central retinal vein occlusion . Only few of the therapeutic strategies in use demonstrated their effectiveness in studies with large patient populations , others have the disadvantage of unacceptable side effects . The aim of the immediate therapy is the improvement of blood perfusion . Prognostically relevant factors like the activity of components of the blood coagulation system , rheology characteristics and predisposing vascular disease risk factors have to be considered . A risk adapted management includes the immediate anticoagulation with heparin . Haemodilution , fibrinolytic therapy and hyperbaric oxygen therapy represent other therapeutic strategies . The efficacy of new promising therapies has to be thoroughly evaluated in studies with large stratified patient populations ." ], "offsets": [ [ 0, 853 ] ] } ]

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"db_id": "C0031001" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 417, 422 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "coagulation" ], "offsets": [ [ 423, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005790" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "rheology" ], "offsets": [ [ 444, 452 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035423" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 495, 502 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 503, 507 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "blood coagulation" ], "offsets": [ [ 417, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005778" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "vascular disease" ], "offsets": [ [ 486, 502 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042373" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "risk factors" ], "offsets": [ [ 503, 515 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035648" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 542, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "anticoagulation" ], "offsets": [ [ 589, 604 ] ], "normalized": [ { "db_name": 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"type": "umlsterm", "text": [ "hyperbaric oxygen therapy" ], "offsets": [ [ 661, 686 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020431" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "therapies" ], "offsets": [ [ 758, 767 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 832, 839 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960736.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "populations" ], "offsets": [ [ 840, 851 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032659" } ] } ]

[]

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DerOpthalmologe.90960741.eng.abstr

[ { "id": "DerOpthalmologe.90960741.eng.abstr-passage-0", "type": "abstract", "text": [ "Problem : The Internet is not structured hierarchically and therefore it distinguishes from today's common knowledge sources . The rapidly growing number of medical websites offers comprehensive but not easy to find information resources and continuing education opportunities for ophthalmologists ." ], "offsets": [ [ 0, 299 ] ] } ]

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[]

DerOpthalmologe.90960777.eng.abstr

[ { "id": "DerOpthalmologe.90960777.eng.abstr-passage-0", "type": "abstract", "text": [ "Objective : Resistance against the anticoagulatory effect of activated protein C ( APC ) is the most common genetic risk factor for venous thromboembolism . In the industrialized nations , the prevalence is 4-7 % of heterozygous symptom carriers and 0.04 % individuals with homozygous defect . The hereditary form is conditioned by a single-point mutation in factor V gene , whose molecular characterization became available in 1994. The fact that so far there are no reports about this specific disease in the German literature signifies a lack in the diagnosis of thromboembolic diseases ." ], "offsets": [ [ 0, 591 ] ] } ]

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[]

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DerOpthalmologe.90960786.eng.abstr

[ { "id": "DerOpthalmologe.90960786.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age ." ], "offsets": [ [ 0, 385 ] ] } ]

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[]

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"arg2_id": "DerOpthalmologe.90960786.eng.abstr-s2-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960786.eng.abstr-s2-r43-t4.2-t6.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960786.eng.abstr-s2-t4", "arg2_id": "DerOpthalmologe.90960786.eng.abstr-s2-t6", "normalized": [] } ]

DerOpthalmologe.90960792.eng.abstr

[ { "id": "DerOpthalmologe.90960792.eng.abstr-passage-0", "type": "abstract", "text": [ "Efficacy and complications of intravitreally injected tissue plasminogen activator ( rt-PA ) and sulfahexafluoride gas ( SF6) in submacular hemorrhage are demonstrated ." ], "offsets": [ [ 0, 169 ] ] } ]

[ { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 13, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 54, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "plasminogen" ], "offsets": [ [ 61, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032140" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "gas" ], "offsets": [ [ 115, 118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017110" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "hemorrhage" ], "offsets": [ [ 140, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019080" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "plasminogen activator" ], "offsets": [ [ 61, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032144" } ] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "tissue plasminogen activator" ], "offsets": [ [ 54, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032143" } ] } ]

[]

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"DerOpthalmologe.90960792.eng.abstr-s1-r24-t6.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r25-t5.1-t3.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r26-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r27-t4.1-t3.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r28-t7.1-t1.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r29-t3.1-t1.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r30-t6.1-t7.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r31-t7.1-t1.1", "type": "diagnoses", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r32-t1.1-t7.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r33-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r34-t3.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r35-t3.1-t6.1", "type": "interacts_with", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerOpthalmologe.90960792.eng.abstr-s1-r36-t4.1-t5.1", "type": "affects", "arg1_id": "DerOpthalmologe.90960792.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960792.eng.abstr-s1-t5", "normalized": [] } ]

DerOpthalmologe.90960797.eng.abstr

[ { "id": "DerOpthalmologe.90960797.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : Confocal indocyanin green angiography ( ICGA ) offers detailed two-dimensional imaging of choroidal pathologies . However , the spatial extension of lesions is not reproduced . We developed a novel method for three-dimensional documentation of choroidal vascular abnormalities ." ], "offsets": [ [ 0, 291 ] ] } ]

[ { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "angiography" ], "offsets": [ [ 39, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002978" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "imaging" ], "offsets": [ [ 92, 99 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "pathologies" ], "offsets": [ [ 113, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 211, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 240, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "abnormalities" ], "offsets": [ [ 276, 289 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0000769" } ] } ]

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[ { "id": "DerOpthalmologe.90960797.eng.abstr-s1-r1-t1.1-t3.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s1-r2-t2.1-t3.1", "type": "method_of", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t2", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-r1-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960797.eng.abstr-s3-r2-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960797.eng.abstr-s3-t3", "arg2_id": "DerOpthalmologe.90960797.eng.abstr-s3-t1", "normalized": [] } ]

DerOpthalmologe.90960813.eng.abstr

[ { "id": "DerOpthalmologe.90960813.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : To assess patient reliability and compliance , most perimeters check for false-positive and -negative answers . In this study the results of catch trials were obtained with video campimetry with respect to age-related changes and differences for tests using increment and decrement stimuli ." ], "offsets": [ [ 0, 301 ] ] } ]

[ { "id": "DerOpthalmologe.90960813.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 20, 27 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "compliance" ], "offsets": [ [ 44, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030680" }, { "db_name": "UMLS", "db_id": "C0009563" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "campimetry" ], "offsets": [ [ 189, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006810" } ] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tests" ], "offsets": [ [ 256, 261 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] } ]

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[ { "id": "DerOpthalmologe.90960813.eng.abstr-s1-r1-t2.1-t1.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s1-r2-t1.1-t2.1", "type": "performs", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "normalized": [] }, { "id": "DerOpthalmologe.90960813.eng.abstr-s2-r1-t1.1-t2.1", "type": "analyzes", "arg1_id": "DerOpthalmologe.90960813.eng.abstr-s2-t1", "arg2_id": "DerOpthalmologe.90960813.eng.abstr-s2-t2", "normalized": [] } ]

DerOpthalmologe.90960822.eng.abstr

[ { "id": "DerOpthalmologe.90960822.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The aim of this study was to analyze risk factors , therapeutic strategies , and functional and anatomic results of eyes with severe suprachoroidal hemorrhage ." ], "offsets": [ [ 0, 173 ] ] } ]

[ { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 17, 20 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 50, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 65, 76 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "anatomic" ], "offsets": [ [ 109, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "eyes" ], "offsets": [ [ 129, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015392" }, { "db_name": "UMLS", "db_id": "C0496836" }, { "db_name": "UMLS", "db_id": "C0023924" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "hemorrhage" ], "offsets": [ [ 161, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019080" } ] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "risk factors" ], "offsets": [ [ 50, 62 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035648" } ] } ]

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[ { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r1-t5.2-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r2-t1.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r3-t1.1-t5.2", "type": "affects", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r4-t4.1-t3.1", "type": "location_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r6-t3.1-t5.2", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r8-t1.1-t5.2", "type": "indicates", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r9-t1.1-t4.1", "type": "disrupts", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r10-t5.2-t3.1", "type": "associated_with", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r11-t1.1-t3.1", "type": "evaluation_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r12-t4.1-t5.3", "type": "part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r13-t4.1-t5.2", "type": "location_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r14-t4.1-t1.1", "type": "produces", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r15-t7.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t7", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerOpthalmologe.90960822.eng.abstr-s1-r16-t4.1-t5.2", "type": "part_of", "arg1_id": "DerOpthalmologe.90960822.eng.abstr-s1-t4", "arg2_id": "DerOpthalmologe.90960822.eng.abstr-s1-t5", "normalized": [] } ]

DerOpthalmologe.90960829.eng.abstr

[ { "id": "DerOpthalmologe.90960829.eng.abstr-passage-0", "type": "abstract", "text": [ "Background : The purpose of this study was to evaluate the course of CMV retinitis after initiation of highly active antiretroviral therapy ( HAART ) and discontinuation of systemic anti-CMV maintenance therapy ." ], "offsets": [ [ 0, 212 ] ] } ]

[ { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "CMV" ], "offsets": [ [ 69, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010825" }, { "db_name": "UMLS", "db_id": "C0285131" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "retinitis" ], "offsets": [ [ 73, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035333" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 132, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "HAART" ], "offsets": [ [ 142, 147 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0887947" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "maintenance" ], "offsets": [ [ 191, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024501" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 203, 210 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOpthalmologe.90960829.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "CMV retinitis" ], "offsets": [ [ 69, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206178" } ] } ]

[]

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DerOrthopaede.00290002.eng.abstr

[ { "id": "DerOrthopaede.00290002.eng.abstr-passage-0", "type": "abstract", "text": [ "The percutaneous epiphysiodesis is recommended as a save and reliable technique . We have performed 21 distal femoral , 17 proximal tibial and 3 proximal fibular percutaneous epiphyseodeses on 25 patients . On 11 patients the epiphysiodesis was caused by an average leg length discrepancy of 2,7 cm ( 1-4 cm ) . 13 patients had angular deformity near the knee joint in frontal plane ( 6 valgus and 7 varus deformities ) . One patient suffered from a combined deformity with 3,5 cm shortened leg and varus deviation of 10 ° . The average deformity angle of the knee was 7,4 ° ( 4 °-16 ° ) . 9 patients have reached maturity . On 3 patients the deformity could be corrected incompetely with residual deformity of 3 ° , 4 ° and 6 ° as a direct result of late referral . On 1 patient an imminent over-correction could be avoided by hemiepiphysiodesis of the residual epiphysis . Till the present follow up the other patients have been corrected as calculated preoperatively . No complications like epiphysiolysis , infection , stiff knee or angular deformities occurred . We prefer the percutaneous epiphysiodesis as a save and minimal invasiv technique instead of the open Phemister-technique to tread leg length discrepancy and angular deformities of the knee in frontal plane ." ], "offsets": [ [ 0, 1276 ] ] } ]

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"type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 315, 323 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 336, 345 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "knee" ], "offsets": [ [ 355, 359 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022742" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 360, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 406, 417 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "knee joint" ], "offsets": [ [ 355, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022745" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 426, 433 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 459, 468 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "leg" ], "offsets": [ [ 491, 494 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023216" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 537, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "knee" ], "offsets": [ [ 560, 564 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022742" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 592, 600 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 630, 638 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 643, 652 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 698, 707 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "direct" ], "offsets": [ [ 734, 740 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700157" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "referral" ], "offsets": [ [ 756, 764 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034927" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 772, 779 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "epiphysis" ], "offsets": [ [ 863, 872 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031939" }, { "db_name": "UMLS", "db_id": "C0014570" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 912, 920 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 975, 988 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "epiphysiolysis" ], "offsets": [ [ 994, 1008 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014571" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s11-t3", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 1011, 1020 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s11-t4", "type": "umlsterm", "text": [ "knee" ], "offsets": [ [ 1029, 1033 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022742" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s11-t5", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 1045, 1056 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 1140, 1149 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "open" ], "offsets": [ [ 1165, 1169 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0266061" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "leg" ], "offsets": [ [ 1199, 1202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023216" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-t4", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 1234, 1245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-t5", "type": "umlsterm", "text": [ "knee" ], "offsets": [ [ 1253, 1257 ] ], "normalized": [ { "db_name": "UMLS", 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[]

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"DerOrthopaede.00290002.eng.abstr-s12-t4", "normalized": [] }, { "id": "DerOrthopaede.00290002.eng.abstr-s12-r17-t5.1-t6.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290002.eng.abstr-s12-t5", "arg2_id": "DerOrthopaede.00290002.eng.abstr-s12-t6", "normalized": [] } ]

DerOrthopaede.00290009.eng.abstr

[ { "id": "DerOrthopaede.00290009.eng.abstr-passage-0", "type": "abstract", "text": [ "Skeletal deformities do occur after conservative or operative fracture treatment , as a consequence of congenital growth disturbance and as sequlae after posttraumatic and haematogenous osteomyelitis . In postinfectious deformities the course of the bone and soft tissue infection plays a decisive role when choosing the appropriate operative technique . Even in non active situations with a closed soft tissues envelope and no draining sinus persistence of germs within the bone has to be anticipated . The biological quality of the bone and the soft tissue envelope is often reduced because of local changes and as a result of multiple local revisions . Consequently wide areas of scar tissue and sclerotic bone are often encountered . The apex of the deformity is in most cases identical with the focus of the active or non active infection . The correction of the deformity at the apex can therefore only be accomplished if the infectious bone is also resected . If a correction is not possible at the apex of the deformity , translation at the osteotomy site is necessary to achieve a correct mechanical axis . The later rather complex operative procedure necessitates intensive preoperative planning and an extensive experience with deformity corrections by external fixators ." ], "offsets": [ [ 0, 1283 ] ] } ]

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[]

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DerOrthopaede.00290039.eng.abstr

[ { "id": "DerOrthopaede.00290039.eng.abstr-passage-0", "type": "abstract", "text": [ "The hexapod is a construction that has been subjected to a great deal of investigation in robotics for use in three-dimensional positioning . One use of it is for positioning of the cockpit in flight simulators . Application of the hexapod principle in the external fixator makes it possible to realize prescribed movements of bone fragments with a simple and stable design . The precise setting of the system requires software that has been developed and optimized for clinical use . Translations , axis corrections and rotations are possible individually and also in combinations for correction of complex deformities . The system has advantages , especially in the case of rotations around the longitudinal axis of the bone and in the realization of translation movements . Because the centres of rotation are taken into account by the mathematical calculations , the planning of corrections is simplified . The hexapod system is described , and its clinical application is presented with reference to case reports ." ], "offsets": [ [ 0, 1019 ] ] } ]

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DerOrthopaede.00290047.eng.abstr

[ { "id": "DerOrthopaede.00290047.eng.abstr-passage-0", "type": "abstract", "text": [ "The introduction of joints in unilateral fixators enables these for multiple deformity corrections . Lengthening and shortening is achieved by changing the length of the fixator telescope . Axial corrections are performed by additive or subtractive techniques using uniplanar joints or by angulation procedures . Translation is done by direct movements of the bone fragments or by metaphyseal \" double angulation \" . Derotation preferably is done as an acute procedure or in the \" ring part \" of a hybrid frame . Unilateral fixators are used to correct and temporarily stabilize until the correction is held by the nintramedullary nail ." ], "offsets": [ [ 0, 637 ] ] } ]

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[]

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DerOrthopaede.00290054.eng.abstr

[ { "id": "DerOrthopaede.00290054.eng.abstr-passage-0", "type": "abstract", "text": [ "Congenital tibial pseudarthrosis ( CTP ) remains one of the most challenging problems in paediatric orthopaedic surgery . With the abandonment of older grafting techniques in favor of vascularized fibular transplants or the Ilizarov method the final outcome has improved and made the prognosis for patients less cumbersome . Using the latter technique in 10 patients , a success rate of 90 % could be reached . Nevertheless , although solid healing occurs in most of the patients nowadays , this is often at the cost of multiple operations before a definite well united , equalized and normally aligned limb can be obtained ." ], "offsets": [ [ 0, 625 ] ] } ]

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[]

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DerOrthopaede.00290058.eng.abstr

[ { "id": "DerOrthopaede.00290058.eng.abstr-passage-0", "type": "abstract", "text": [ "Nine patients with achondroplasia and one patient with Apert syndrome underwent the surgical lengthening of both humerus and simultaneous correction of both associated bone deformity . An unilateral external fixator was applied to the lateral aspect of the humerus with four half-pins and percutaneous predrilling osteotomy was performed at the apex of flexion deformity of the bone . During the waiting period before distraction , the flexion deformity of the distal humerus was corrected using an additional external fixator . Slow gradual distraction was subsequently carried out at a rate of 0.25 mm every 6 hours . The average lengthening was 8 cm ( range 7.5 to 9 cm ) , the overall treatment time 312 days ( range 192 to 406 days ) , and the average healing index 39.0 days/cm . The average correction of the elbow flexion deformity was 20 degrees . We believe this treatment is useful to improve the function of the arms and the activity of daily living for the patients with bilateral short humeri ." ], "offsets": [ [ 0, 1008 ] ] } ]

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"text": [ "humerus" ], "offsets": [ [ 113, 120 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020164" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 168, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 173, 182 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "Apert syndrome" ], "offsets": [ [ 55, 69 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0685204" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "humerus" ], "offsets": [ [ 257, 264 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020164" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "osteotomy" ], "offsets": [ [ 314, 323 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029468" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 361, 370 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 378, 382 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "external fixator" ], "offsets": [ [ 199, 215 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079321" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 404, 410 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 444, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "humerus" ], "offsets": [ [ 468, 475 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020164" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "external fixator" ], "offsets": [ [ 510, 526 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079321" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "overall" ], "offsets": [ [ 681, 688 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282416" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 689, 698 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "time" ], "offsets": [ [ 699, 703 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040223" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "index" ], "offsets": [ [ 765, 770 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021200" }, { "db_name": "UMLS", "db_id": "C0918012" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "elbow" ], "offsets": [ [ 816, 821 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013769" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "deformity" ], "offsets": [ [ 830, 839 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 873, 882 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 908, 916 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "arms" ], "offsets": [ [ 924, 928 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003792" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 970, 978 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290058.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "humeri" ], "offsets": [ [ 1000, 1006 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020164" } ] } ]

[]

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DerOrthopaede.00290068.eng.abstr

[ { "id": "DerOrthopaede.00290068.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of this study was to compare the initial stiffness of two techniques for posterior interbody lumbar fusion ( PLIF ) by a finite element approach . Thus a finite element model of a human L3/4 spinal segment was generated . Stiffness of the intact model was tested under compression ( 600 N ) , torsion ( 25 Nm ) and shearing forces ( 250 N ) without preload . The results were compared to the stiffness following simulation of PLIF with two BAK-Cages and PLIF with two Harms-Cages and additional posterior screw-rod-osteosynthesis . PLIF with two BAK-Cages resulted in a loss of stiffness in compression , torsion and shearing . PLIF with two Harms-Cages and posterior osteosynthesis resulted in an increase of stiffness in compression , torsion and shearing ." ], "offsets": [ [ 0, 771 ] ] } ]

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[]

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DerOrthopaede.00290080.eng.abstr

[ { "id": "DerOrthopaede.00290080.eng.abstr-passage-0", "type": "abstract", "text": [ "As all living cell systems , human chondrocytes are provided with a membrane potential . For its origin the existence of ion channels at the cell membrane is an essential prerequisite . In non-human chondrocytes , different ion channels could already be identified . A connection between the potassium channel activity and the proliferation has been detected in different human cell systems . Whereas , the proof of a connection between ion channel activity of human chondrocytes and the proliferation has yet to be established . In this study the concentration-dependent influence of the ion channel modulators tetraethylammonium ( TEA ) , 4-amino-pyridin ( 4-AP ) , 4 ' , 4 ' diisothiocyanato-stilbene-2,2 ' disulfonic acid ( DIDS ) , 4-acetamido-4 ' isothiocyano-2,2 ' disulfonic acid stilbene ( SITS ) and verapamil on the membrane potential and the proliferation of human chondrocytes was investigated using flow cytometry . The results show an effect of the used ion channel modulators causing a change of the membrane potential of human chondrocytes . The decrease of the membrane potential by 18 % was measured with 0.25 mmol/l verapamil meaning the maximal measurable effect compared with a control group . When measuring DNA distribution , it became apparent that the human chondrocytes are diploid cells with a very low proliferation tendency . These results allow the conclusion of an influence of ion channel modulators on chondrocyte proliferation ." ], "offsets": [ [ 0, 1463 ] ] } ]

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[]

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"DerOrthopaede.00290080.eng.abstr-s9-r7-t5.1-t2.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290080.eng.abstr-s9-t5", "arg2_id": "DerOrthopaede.00290080.eng.abstr-s10-t2", "normalized": [] }, { "id": "DerOrthopaede.00290080.eng.abstr-s10-r1-t2.1-t3.1", "type": "produces", "arg1_id": "DerOrthopaede.00290080.eng.abstr-s10-t2", "arg2_id": "DerOrthopaede.00290080.eng.abstr-s10-t3", "normalized": [] }, { "id": "DerOrthopaede.00290080.eng.abstr-s10-r2-t3.1-t1.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290080.eng.abstr-s10-t3", "arg2_id": "DerOrthopaede.00290080.eng.abstr-s10-t1", "normalized": [] }, { "id": "DerOrthopaede.00290080.eng.abstr-s10-r3-t1.1-t3.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290080.eng.abstr-s10-t1", "arg2_id": "DerOrthopaede.00290080.eng.abstr-s10-t3", "normalized": [] }, { "id": "DerOrthopaede.00290080.eng.abstr-s10-r4-t3.1-t2.1", "type": "disrupts", "arg1_id": "DerOrthopaede.00290080.eng.abstr-s10-t3", "arg2_id": "DerOrthopaede.00290080.eng.abstr-s10-t2", "normalized": [] } ]

DerOrthopaede.00290085.eng.abstr

[ { "id": "DerOrthopaede.00290085.eng.abstr-passage-0", "type": "abstract", "text": [ "The cell activity of human bone derived cell cultures was studied after mechanical stimulation by cyclic strain at a magnitude occurring in physiologically loaded bone tissue . Monolayers of subconfluently grown human bone derived cells were stretched in rectangular silicone dishes with cyclic uniaxial movement along their longitudinal axes . Strain was applied over two days for 30 min per day with a frequency of 1 Hz and a strain magnitude of 1000 µstrain. Cyclic stretching of the cells resulted in an increased proliferation ( 10-48 % ) and carboxyterminal collagen type I propeptide release ( 7-49 % ) of human cancellous bone derived osteoblasts while alkaline phosphatase activity and osteocalcin release were significantly reduced by 9-25 % and 5-32 % respectively . These results demonstrate that cyclic strain at physiologic magnitude leads to an increase of osteoblast activities related to matrix production while those activities which are characteristic for the differentiated osteoblast and relevant for matrix mineralization are decreased ." ], "offsets": [ [ 0, 1059 ] ] } ]

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"DerOrthopaede.00290085.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "release" ], "offsets": [ [ 591, 598 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 613, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 630, 634 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "osteoblasts" ], "offsets": [ [ 643, 654 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029418" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t10", "type": "umlsterm", "text": [ "phosphatase" ], "offsets": [ [ 670, 681 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031678" } ] }, { "id": "DerOrthopaede.00290085.eng.abstr-s3-t11", "type": "umlsterm", 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[]

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"DerOrthopaede.00290085.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290085.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290085.eng.abstr-s4-r4-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290085.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290085.eng.abstr-s4-t3", "normalized": [] } ]

DerOrthopaede.00290100.eng.abstr

[ { "id": "DerOrthopaede.00290100.eng.abstr-passage-0", "type": "abstract", "text": [ "Successful and cartilage-specific cultivation of chondrocytes requires a stable phenotype during the in vitro culture period . This is based on a differentiated extracellular matrix synthesis . The alginate system as a three-dimensional support is a useful system to culture chondrocytes and to analyze the biochemical processes in this system . Talar cartilage from the talocrural joints of 40 different donors were obtained through the Regional Organ Bank of Illinois within 24 hours of death . In 65 % of the tissues the cartilage was classified as being undamaged . In these studies we were interested in the results of short-term culture over 14 days . Cell proliferation , total collagen content and total proteoglycan content were measured in the different matrix compartments and were visualized by histology and immunohistochemistry . Already after 7 days in culture the adult human chondroctes looked intact and formed a stable and cell-associated cartilage-specific extracellular matrix in the presence of 10 % calf serum . This could be also demonstrated in the presence of IGF-I . With regards to the collagen content IGF-I at a concentration of 50 ng/ml seemed to induce an equal effect to 10 % serum ; with regards to the proteoglycan content IGF-I at a concentration of 20 ng/ml was equivalent . These encouraging preliminery results may lead to a new approach in tissue engineering for chondrocyte transplantation in combination with their extracellular matrix ." ], "offsets": [ [ 0, 1479 ] ] } ]

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[]

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DerOrthopaede.00290107.eng.abstr

[ { "id": "DerOrthopaede.00290107.eng.abstr-passage-0", "type": "abstract", "text": [ "Bone metabolism is influenced by systemic and local acting hormons . Bone morphogenetic proteins ( BMPs ) as representatives of the latter substances are known to have the ability for ectopic bone formation . Within this study , we investigated the influence of different growth factors on the proliferation- and differentiation rate of osteoblast-like cells . For that purpose , human osteoblast-like cells ( HPOC ) were incubated in the presence of either recombinant BMP-4 of the genome of xenopus laevis ( rxBMP-4), recombinant human BMP 2 ( rhBMP-2), transforming growth factor-ss ( TGF-ss ) or basic fibroblast growth factor ( rh-bFGF ) in two different concentrations each ( 10 ng/ml and 50 ng/ml ) . Cell proliferation was measured within a MTT [ 3- ( 4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromid ] assay , the amount of cell differentiation by the activity of alcaline phosphatase . Rx-BMP-4 induced a differentiation of HPOC to almost the same extent as rhBMP-2, whereas the addition of rh-bFGF , applied at the same concentration , failed to have any influence on cell differentiation . However , rh-bFGF provoked an increase in cell proliferation when compared with unstimulated HPOC , while rhBMP-2 and rxBMP-4 showed no effect on proliferation . TGF-ss influenced bone proliferation as well as differenciation significantly . The equipotent effect of recombinant human BMP-2 and recombinant BMP-4 obtained from Xenopus laevis with regard to differentiation and proliferation of human primary osteoblast-like cells originates either in the fact that target cells have receptors for BMP 2 as well as BMP 4 , or that both BMP's link to the same receptor with almost the same affinity ." ], "offsets": [ [ 0, 1708 ] ] } ]

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"db_id": "C0527443" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t3", "type": "umlsterm", "text": [ "BMP-4" ], "offsets": [ [ 1417, 1422 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0530979" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t4", "type": "umlsterm", "text": [ "Xenopus" ], "offsets": [ [ 1437, 1444 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043342" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t5", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 1504, 1509 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t6", "type": "umlsterm", "text": [ "osteoblast-like" ], "offsets": [ [ 1518, 1533 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029418" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t7", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 1534, 1539 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t8", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 1582, 1587 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t9", "type": "umlsterm", "text": [ "BMP" ], "offsets": [ [ 1607, 1610 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0053932" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t10", "type": "umlsterm", "text": [ "BMP" ], "offsets": [ [ 1624, 1627 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0053932" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t11", "type": "umlsterm", "text": [ "link" ], "offsets": [ [ 1651, 1655 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0208973" } ] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-t12", "type": "umlsterm", "text": [ "Xenopus laevis" ], "offsets": [ [ 1437, 1451 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043343" } ] } ]

[]

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"DerOrthopaede.00290107.eng.abstr-s9-t8", "arg2_id": "DerOrthopaede.00290107.eng.abstr-s9-t11", "normalized": [] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-r30-t7.1-t1.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290107.eng.abstr-s9-t7", "arg2_id": "DerOrthopaede.00290107.eng.abstr-s9-t1", "normalized": [] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-r31-t8.1-t10.1", "type": "produces", "arg1_id": "DerOrthopaede.00290107.eng.abstr-s9-t8", "arg2_id": "DerOrthopaede.00290107.eng.abstr-s9-t10", "normalized": [] }, { "id": "DerOrthopaede.00290107.eng.abstr-s9-r32-t8.1-t1.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290107.eng.abstr-s9-t8", "arg2_id": "DerOrthopaede.00290107.eng.abstr-s9-t1", "normalized": [] } ]

DerOrthopaede.00290112.eng.abstr

[ { "id": "DerOrthopaede.00290112.eng.abstr-passage-0", "type": "abstract", "text": [ "The transplantation of chondrogenic cells in a supportive carrier structure proved to be a promising alternative for the treatment of cartilage defects . In the study presented we focused on the transplantation of allogeneic chondrocytes in a biodegradable polymer scaffold ( PGLA/Polydioxanon ) in articular cartilage defects in a rabbit defect model . Isolated allogeneic chondrocytes embedded in a PGLA polymer scaffold were transplanted into osteochondrogenic defects of the patellar groove and compared with empty defects and transplants of polymer scaffolds without cells . The histological and histochemical analysis was performed after 4 and 12 weeks . The transplant integration and the architecture of the newly formed cartilage were evaluated with a semiquantitative score . After 4 weeks the development of a hyaline-like cartilage tissue of the cell-polymer-transplants was observed , after 12 weeks the defects were nearly completely filled with hyaline-like cartilage . The biodegradation of the polymer construct did not affect the histological structure of the transplant area . Defects of the groups with empty defect and polymer transplants without cells revealed no or insufficient healing indices . The study demonstrated that biodegradable polymers served as suitable carriers for the chondrocyte transplantation , which is due to the in-vitro establishment of a semi-solid cartilage transplant and the resulting effective transplant fixation into the defect . In-vivo the polymer cell transplants seem to provide a supportive microenvironment for the development of hyaline cartilage . The controlled release of morphogenic factors or bioactive molecules and the use of pluripotent mesenchymal progenitor cells opens new perspectives for the optimization of cartilage repair procedures ." ], "offsets": [ [ 0, 1810 ] ] } ]

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[]

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DerOrthopaede.00290120.eng.abstr

[ { "id": "DerOrthopaede.00290120.eng.abstr-passage-0", "type": "abstract", "text": [ "Current methods for articular cartilage repair are unpredictable with respect to clinical success . In the present study , we investigated the ability of cells from articular cartilage , perichondrium , and costochondral resting zone to form new cartilage when loaded onto biodegradable scaffolds and implanted into calf muscle pouches of nu/nu mice . Prior in vitro studies showed that platelet derived growth factor-BB ( PDGF-BB ) , but not transforming growth factor beta-1 ( TGF-1), basic fibroblast growth factor , or bone morphogenetic protein-2 promoted proliferation and extracellular matrix sulfation of resting zone chondrocytes without causing the cells to exhibit a hypertrophic chondrocyte phenotype . TGF-1 has also been shown to stimulate chondrogenesis by multipotent chondroprogenitor cells like those in the perichondrium . In addition , PDGF-BB has been shown to modulate chondrogensis by resting zone cells implanted in poly ( D , L-lactide-co-glycolide ) ( PLG ) scaffolds . In the present study we examined whether the cartilage formation is dependent on state of chondrocyte maturation and whether the pretreatment of chondrocytes with growth factors has an influence on the cartilage formation . Scaffolds were manufactured from 80 % PLG with a 75:25 lactide : glycolide ratio and 20 % modified PLG with a 50:50 lactide : glycolide ratio ( PLG-H scaffolds ) . For each experimental group , four nude mice received two identical implants , one in each calf muscle resulting in an N = 8 implants : PLG-H scaffolds alone ; PLG-H scaffolds with cells derived from either the femoral articular cartilage , costochondral periochondrium , or costochondral resting zone cartilage of 125 g male Sprague-Dawley rats ; PLG-H scaffolds with either articular chondrocytes or resting zone chondrocytes that were pretreated with 37,5 ng/ml rhPDGF-BB for 4 h or 24 h before implantation , or with perichondrial cells treated with PDGF-BB plus 0,22 ng/ml rhTGF-1 for 4 h and 24 h . At 4 or 8 weeks after implantation , samples were harvested and analyzed histomorphometrically for new cartilage formed , area of residual implant and area of fibrous connective tissue . Only resting zone cells showed the ability to form new cartilage at a heterotopic site in this study . There was no neocartilage found in nude mice with implants loaded with either articular chondrocytes or perichondrial cells . Pretreatment of resting zone chondrocytes for 4 h prior to implantation significantly increased the amount of newly formed cartilage after 8 weeks and suppressed chondrocyte hypertrophy . The amount of fibrous connective tissue around implants containing either articular chondrocytes or perichondrial cells decreased with time , whereas the amount of fibrous connective tissue around implants containing resting zone chondrocytes pretreated with PDGF-BB was increased . The results showed that resting zone cells can be successfully incorporated into biodegradable porous PLG scaffolds and can induce new cartilage formation in a non-weight-bearing site . Articular chondrocytes as well as perichondrial cells did not have the capacity for neochondrogenesis when implanted heterotopically in this model ." ], "offsets": [ [ 0, 3210 ] ] } ]

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[]

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DerOrthopaede.00290129.eng.abstr

[ { "id": "DerOrthopaede.00290129.eng.abstr-passage-0", "type": "abstract", "text": [ "Different methods are available for the treatment of osseous defects . In recent years the use of autologous bone was established as the golden standard . However , significant disadvantages are limited availability of the bone graft and its harvest implies additional morbidity for the patient . Alternatives to the use of autologous bone , as allogeneic bone from bone banks or biomaterials like hydroxyapatite are therefore of special interest . However , the currently available methods have severe disadvantages ; allogenic bone carries a high risk of transmitting infectious diseases , most biomaterials show an unsatisfying osseous integration as well as prolonged healing with disability for the patient . Therefore , the aim has to be the development of a biomaterial that is as close as possible to human bone . In this in vitro study the natural bone mineral Bio-Oss/Orthos was used as a matrix for human osteoblast - like cells isolated from bone marrow of healthy patients . Even after three months the cell showed typical osteblast-like behaviour . Histologic evaluation demonstrated the ability of Bio-Oss/Orthos to guide cell growth within its matrix structure and therefore mimics in vivo situation of the healthy bone . The results show that culturing human osteoblast-like cells under standardised conditions is possible and that the combination of human osteoblast-like cell with an appropriate matrix may have the potential for a new treatment option of osseous defects ." ], "offsets": [ [ 0, 1492 ] ] } ]

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DerOrthopaede.00290145.eng.abstr

[ { "id": "DerOrthopaede.00290145.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of our study was to examine the potential of autologous perichondrial tissue to form meniscal replacements . Eighteen mature sheep were used . In 12 animals a complete meniscal resection was performed ; replacement was formed using strips of autologous perichondrial tissue explanted from the lower rib ; six animals with a complete meniscal resection but without any replacement served as controls . In all animals restriction from weight-bearing was achieved by means of transsection and partial achilles-tendon resection . Six animals each , 4 of group T and 2 of group C , were sacrificed after 3 , 6 , and 12 months . Perichondrial grafts and the underlying articular cartilage were removed and investigated by gross macroscopic examination , by means of light and scanning electron microscopy , polarized light examination , and biomechanical tests evaluating the failure stress and tensile modulus . In all transplanted animals a new perichondrial meniscus developed . After 3 months the transplants resembled in size and thickness normal menisci , while in the control animals only small rims of spontaneously grown tissue were detectable . Microscopically , the perichondrial menisci exhibited similarity to normal collagen fiber orientation and cellular characteristics , but , in their central region , areas of calcification disturbed the regular tissue differentiation . In contrast , spontaneously grown tissue in control animals lacked normal fiber orientation and cellularity . Scanning electron-microscopy of perichondrial menisci revealed surface characteristics similar to normal sheep menisci without fissures and lacerations , while the control specimens exhibited such defects . The femoral and tibial cartilage being in contact with the new menisci showed normal surface characteristics apart from one animal with slight surface irregularities . Control animals showed surficial lesions after 3 months , and the extent increased from 6 to 12 months postoperatively . Exemplary microangiographies of the newly grown tissue exhibited a less intense vascularisation after three months when compared to normal menisci with an improving tendency after 6 and 12 months . Biomechanically , values of the failure stress as well as of the tensile modulus of perichondrial menisci were significantly lower than those of normal contralateral menisci . But , spontaneously regenerated tissue in meniscectomized animals exhibited even smaller values also with significant differences towards original menisci . There were no significant differences in values of newly grown perichondrial menisci and spontaneously grown tissue ." ], "offsets": [ [ 0, 2650 ] ] } ]

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"DerOrthopaede.00290145.eng.abstr-s11-t4", "normalized": [] }, { "id": "DerOrthopaede.00290145.eng.abstr-s11-r9-t5.1-t2.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290145.eng.abstr-s11-t5", "arg2_id": "DerOrthopaede.00290145.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290145.eng.abstr-s11-r10-t5.1-t4.1", "type": "result_of", "arg1_id": "DerOrthopaede.00290145.eng.abstr-s11-t5", "arg2_id": "DerOrthopaede.00290145.eng.abstr-s11-t4", "normalized": [] }, { "id": "DerOrthopaede.00290145.eng.abstr-s12-r1-t1.1-t2.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290145.eng.abstr-s17-t1", "arg2_id": "DerOrthopaede.00290145.eng.abstr-s17-t2", "normalized": [] }, { "id": "DerOrthopaede.00290145.eng.abstr-s16-r1-t1.1-t2.1", "type": "part_of", "arg1_id": "DerOrthopaede.00290145.eng.abstr-s17-t1", "arg2_id": "DerOrthopaede.00290145.eng.abstr-s17-t2", "normalized": [] } ]

DerOrthopaede.00290151.eng.abstr

[ { "id": "DerOrthopaede.00290151.eng.abstr-passage-0", "type": "abstract", "text": [ "Hyaline cartilage is thought to be unable to regenerate . All efforts so far - including autologous chondrocyte cell transplantation - to reconstruct cartilage defects in joints have not been totally convincing . However , mesenchymal cells are able to differentiate into chondrocytes under mechanical pressure conditions . In this study , an open porous resorbable two-layer \" bioimplant \" was constructed in which mechanical pressure was exerted onto mesenchymal cells when migrated into the open porous structure of the bioimplant . Differentiation of the cells into chondrocytes was thus induced . The bioimplants were implanted into the medial condyles of nine rabbits and left in place for eight or twelve weeks , respectively . In seven of these cases , cartilage formation was found , in contrary to the controls in which only connective tissue and bone had grown into the empty holes . The new bioimplants have proven their effectiveness in cartilage defect repair and might evolve in the future as a new alternative treatment of full thickness defects of joint surfaces ." ], "offsets": [ [ 0, 1081 ] ] } ]

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[]

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DerOrthopaede.00290158.eng.abstr

[ { "id": "DerOrthopaede.00290158.eng.abstr-passage-0", "type": "abstract", "text": [ "Successful transplantation of autologous chondrocytes for repair of articular cartilage defects requires an undisturbed matrix-synthesis of the transplanted cells . This , in turn , is dependent on the composition of the synovial fluid ( SF ) of the respective joint . We addressed the question whether analysis of a patient's SF can predict the rate of matrix-synthesis of articular cartilage exposed to this SF in vitro . SF was obtained from 115 patients with disorders of the knee , including gonarthrosis ( n = 44 ) , meniscal tears ( n = 10 ) , rheumatoid arthritis ( n = 53 ) , and reactive arthritides ( n = 8 ) . In the SF , the following parameters were determined : Interleukin-1, IL-6, IL-8, IL-1-RA, TNF , Insulin-like growth-factor I ( IGF-I ) , IGF-II , IGF-binding protein-2 ( IGFBP-2), IGFBP-3 as well as total proteinase activity and total collagenase activity . To assess the effect of SF on the matrix synthesis of articular chondrocytes , bovine cartilage was incubated in the presence of SF , and the rate of proteoglycan synthesis subsequently determined . In some cases , a monoclonal antibody directed against IGF-I was added . SF from patients with OA or trauma , respectively , stimulated PG-synthesis of bovine cartilage more markedly than did SF from patients with rheumatic arthritides . On the average , 60 percent of the SF-induced increase of cartilage matrix synthesis could be titrated out by an anti-IGF-I-AB . The best predictor for the SF-effects on PG-synthesis of exposed cartilage was the proportion of free IGF-I ( r = 0.573 , p 0.001 , Spearman rank correlation ) followed by the SF-concentrations of IGF-I ( with a positive sign ) , IGFBP-3, IL-1, and TNF ( all with a negative sign ) . According to our data , IGF-I is the most important anabolic factor in human SF with respect to cartilage PG-synthesis . The proportion of free IGF-I seems to be of special importance in this regard . Low SF-levels of free IGF-I could be identified as a possible risk-factor for a sub-optimal protoeglycan synthesis of chondrocytes exposed to this synovial milieu ." ], "offsets": [ [ 0, 2096 ] ] } ]

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"db_id": "C0243067" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 157, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "articular cartilage" ], "offsets": [ [ 68, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007303" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 261, 266 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "synovial fluid" ], "offsets": [ [ 221, 235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039097" } ] }, { "id": "DerOrthopaede.00290158.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": 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[]

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DerOrthopaede.00290174.eng.abstr

[ { "id": "DerOrthopaede.00290174.eng.abstr-passage-0", "type": "abstract", "text": [ "The load limit of a tendon is expressed by the not linear force/lenghtening behavior . It is determined by the interrelation between load and load-bearing capacity . The load of a tendon results from exogenous , endogenous and temporal factors . The property factors and the aging influence the load-bearing capacity of a tendon . Partial ruptures show necrosis , calcification and fiber swelling . The attachment area shows a mineralization of the cartilage zone , a loss of the collagen fibrils and calcifications . The tendon ruptur knows extrinsic and intrinsic causes . Primary are micro and macrovascular tendon alterations , usually favour the rupture of tendons ." ], "offsets": [ [ 0, 671 ] ] } ]

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[]

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DerOrthopaede.00290182.eng.abstr

[ { "id": "DerOrthopaede.00290182.eng.abstr-passage-0", "type": "abstract", "text": [ "This review describes structure , function and healing of tendinous tissue and discusses new biologically based treatment options to modulate tendon healing . The repair process after tendon rupture results in a morphologically different and biomechanically inferior structure compared to a normal tendon . The collagen fibril diameters are decreased months after the traumatic lesion and show also different phenotypes . We know that cytokines and growth factors are key components for normal tissue development and regulate wound healing processes . Some growth factors have been detected to influence tenocytes by promoting cell proliferation and matrix synthesis . Application of the adequate growth factors at certain periods during the repair process might improve the healing result after tendon rupture . However , most of these growth factors are proteins which are rapidly metabolized by the organism . Transfer of growth factor genes into tenocytes might eliminate this problem by a continuous local release of growth factors at the healing site ." ], "offsets": [ [ 0, 1058 ] ] } ]

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"phenotypes" ], "offsets": [ [ 409, 419 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031437" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "cytokines" ], "offsets": [ [ 435, 444 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079189" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 449, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 494, 500 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 501, 512 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s4-t5", 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"DerOrthopaede.00290182.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "growth factors" ], "offsets": [ [ 557, 571 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018284" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 697, 703 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "periods" ], "offsets": [ [ 723, 730 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 742, 748 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 796, 802 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "rupture" ], "offsets": [ [ 803, 810 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035955" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "growth factors" ], "offsets": [ [ 697, 711 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018284" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 837, 843 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "proteins" ], "offsets": [ [ 856, 864 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOrthopaede.00290182.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "organism" ], "offsets": [ [ 902, 910 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029235" } ] }, { "id": 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[]

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DerOrthopaede.00290188.eng.abstr

[ { "id": "DerOrthopaede.00290188.eng.abstr-passage-0", "type": "abstract", "text": [ "Tendon sutures belong to the bases of surgical activity . Particularly in the last decades these sutures experienced a substantial upswing by the introduction of new techniques and materials . Target is to reestablish the tendon function . In order to achieve this target , it requires knowledge of tendon healing . An outline of suture materials , in particular specific suture techniques as well as the subsequent treatment is given . With different localizations of the tendon lesions one deals ." ], "offsets": [ [ 0, 499 ] ] } ]

[ { "id": "DerOrthopaede.00290188.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Tendon" ], "offsets": [ [ 0, 6 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "sutures" ], "offsets": [ [ 7, 14 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038969" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "surgical" ], "offsets": [ [ 38, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "sutures" ], "offsets": [ [ 97, 104 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038969" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 166, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 222, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 229, 237 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 286, 295 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 299, 305 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 379, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 416, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "suture techniques" ], "offsets": [ [ 372, 389 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038968" } ] }, { "id": "DerOrthopaede.00290188.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 473, 479 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] } ]

[]

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DerOrthopaede.00290196.eng.abstr

[ { "id": "DerOrthopaede.00290196.eng.abstr-passage-0", "type": "abstract", "text": [ "Since the life span of our society is increasing and the expectation of high functional demands is growing more and more older people take part in sports activities emphasises the necessity of early diagnosis of rotator cuff lesions and their correct treatment . The goal of any diagnostic means should be a proper treatment of rotator cuff lesions according to the detected pathology . New arthroscopic techniques to surgically reconstruct rotator cuff tears have brought the operative repair techniques another step further . In cases of large and complex cuff tears the surgeon can individually select an adequate reconstruction procedure which includes anatomical- , partial- , tendon-transfer and muscle-transfer repairs . In cases of irreparable tears with cuff-tear arthropathy and consecutive superior migration of the humeral head hemiarthroplasty or the inverse deltoid prosthesis have to be considered . Based on clinical , radiological and arthroscopic findings we developed algorithms that will lead to the best suited procedure for a given lesion ." ], "offsets": [ [ 0, 1062 ] ] } ]

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[]

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DerOrthopaede.00290209.eng.abstr

[ { "id": "DerOrthopaede.00290209.eng.abstr-passage-0", "type": "abstract", "text": [ "Ruptures of the long head of the M. biceps humeri are commonly caused by degenerative changes within the tendon . They are associated with pathologies of the subacromial space . The loss of power regarding elbow flexion and supination amounts to 8 to 21 % after conservative treatment . Refixation offers a small but evident improvement of flexion and supination power . Especially endurance is improved . The number of cases with remaining light or marked weakness is reduced by more than 50 % . Deformity by the slipped muscle can be corrected effectively . Function of the glenohumeral joint can only be improved if associated subacromial problems are identified and treated simultaneously . As complications are uncommon surgery should be recommended to young and active patients and should at least be offered to less active patients . Ruptures of the distal tendon are less common . Thirteen patients were re-examined after operative repair for distal biceps tendon avulsion and 277 reported cases were reviewed . After conservative management ( n = 20 ) the power of flexion will remain reduced by 30 %-40 % , that of supination by more than 50 % . The loss of flexion power , as well as the deformity can be diminished by attachment of the distal biceps to the brachialis muscle ( n = 22 ) . The anatomic reinsertion ( n = 248 ) additionally reduces the loss of supination power to 0 %-25 % , but bears a higher risk of complications . Using the ' double-incision technique ' ( n = 105 of 248 ) does not decrease the risk of nerval lesions but increases the incidence of radioulnar synostosis . The use of suture anchors provides a nice way of fixation of the tendon but does not facilitate the approach to the tuberosity . The distal biceps tendon rupture should be treated operatively . The adequate method of repair is to be determined individually ." ], "offsets": [ [ 0, 1861 ] ] } ]

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[]

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"DerOrthopaede.00290209.eng.abstr-s18-t1", "normalized": [] }, { "id": "DerOrthopaede.00290209.eng.abstr-s17-r2-t1.1-t2.1", "type": "location_of", "arg1_id": "DerOrthopaede.00290209.eng.abstr-s18-t1", "arg2_id": "DerOrthopaede.00290209.eng.abstr-s18-t2", "normalized": [] } ]

DerOrthopaede.00290216.eng.abstr

[ { "id": "DerOrthopaede.00290216.eng.abstr-passage-0", "type": "abstract", "text": [ "Injuries of the flexor tendon are usually open injuries . In most cases primary treatment is therefore seldom performed by orthopaedic surgeons . This is different for injuries of the extensor tendon . Three quarters of injuries of the extensor tendon are closed injuries . Therefore we do go into primary and secondary reconstruction of the flexor tendon , but focus on primary and secondary reconstruction of the extensor tendon in the most common zones ( 1 , Th I , 3 , Th III ) ." ], "offsets": [ [ 0, 483 ] ] } ]

[ { "id": "DerOrthopaede.00290216.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Injuries" ], "offsets": [ [ 0, 8 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "flexor" ], "offsets": [ [ 16, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175090" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 23, 29 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "open" ], "offsets": [ [ 42, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0266061" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 47, 55 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 80, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 168, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 193, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 220, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 263, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 310, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "flexor" ], "offsets": [ [ 342, 348 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175090" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 349, 355 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 383, 392 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "DerOrthopaede.00290216.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "tendon" ], "offsets": [ [ 424, 430 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039508" } ] } ]

[]

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DerOrthopaede.00290235.eng.abstr

[ { "id": "DerOrthopaede.00290235.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of acute of Achilles tendon rupture experienced a dynamic development in the last ten years . Decisive for this development was the application of MRI and above all the ultrasonography in the diagnostics of the pathological changes and injuries of tendons . The question of ruptue morphology as well as different courses of healing could be now evaluated objectively . These advances led consequently to new modalities in treatment concepts and rehabilitation protocols . The decisive input for improvements of the outcome results and particularly the shortening of the rehabilitation period came with introduction of the early functional treatment in contrast to immobilizing plaster treatment . In a prospective randomized study ( 1987-1989 ) at the Trauma Dept . of the Hannover Medical School could show no statistical differences comparing functional non-operative with functional operative therapy with a special therapy boot ( Variostabil/Adidas ) . The crucial criteria for therapy selection results from the sonografically measured position of the tendon stumps in plantar flexion ( 20 ° ) . With complete adaptation of the tendons ' ends surgical treatment does not achieve better results than non-operative functional treatment in term of tendon healing and functional outcome . Regarding the current therapeutic standards each method has is advantages and disadvantages . Both , the operative and non-operative functional treatment enable a stable tendon healing with a low risk of rerupture ( 1-2 % ) . Meanwhile there is consensus for early functional aftertreatment of the operated Achilles ' tendons . There seems to be a trend towards non-operative functional treatment in cases of adaquate sonografical findings , or to minimal invasive surgical techniques ." ], "offsets": [ [ 0, 1790 ] ] } ]

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[]

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DerOrthopaede.00290251.eng.abstr

[ { "id": "DerOrthopaede.00290251.eng.abstr-passage-0", "type": "abstract", "text": [ "Complete traumatic rupture of the tibialis posterior tendon is absolutely rare . From the scarce case reports in the medical literature a extreme pronation-abduction or pronation-external rotation mechanism according to the Lauge-Hansen classification can be presumed , leading to a malleolar fracture because of forced pronation , external rotation and dorsiflexion of the foot . With primary suture the prognosis is favorable . Traumatic dislocations , mostly with luxatio pedis sub talo , are treated by atraumatic reduction and refixation of the retinaculum . Again , the prognosis is favorable . Incomplete traumatic rupture of the tibialis posterior tendon with development of posttraumatic pes plano valgus , according to case reports and our own experience result from severe pronation-external rotation-soft tissue injuries as well as with pronation-abduction or pronation-external rotation-type ankle fractures . In these cases no macroscopic rupture of the tendon is evident , however occult interstitial microruptures can occur because of excessive stretching , which can be determined histologically . If conservative measures fail , a modified Evans osteotomy to lenghten the lateral foot column is indicated . Degenerative complete and incomplete ruptures of the tibialis posterior tendon are predominantly seen in women more than 42 years old . Staging of this entity can be achieved with clinical tests ( muscular force , external rotation ) , ultrasound , weight-bearing x-rays , CT and MRT . According to the degree of decompensation of tendon function , treatment consists of augmentation , modified Evans procedure or triple arthrodesis of the hindfoot ." ], "offsets": [ [ 0, 1675 ] ] } ]

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[]

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DerOrthopaede.00290274.eng.abstr

[ { "id": "DerOrthopaede.00290274.eng.abstr-passage-0", "type": "abstract", "text": [ "Fracture care in a geriatric population should lead to a mobilisation with full weight bearing as soon as possible after the accident . Osteoporosis and associated preexisting disease influences the kind of fracture care as well as the social situation . A retrospective analysis of 888 consecutive patients from 1994 to 1998 showed that the fracture risk for a second independent bony lesion was 5,2 % in this population with a mean age of 83,4 years ( 75y-97,2 y ) . 946 fractures were treated operatively with a overall reoperation rate of 10 % . 3,1 % were soft tissue revisions due to infection , 2,0 % were because of implant failure in connection with a deep infection and 5,2 % of the reoperation were indicated because of implant failure alone . Distribution of complications showed the advantage of closed , indirect reduction and intramedullary devices and primary hemiarthroplasty in femoral and humeral head fractures ." ], "offsets": [ [ 0, 932 ] ] } ]

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[]

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DerOrthopaede.00290281.eng.abstr

[ { "id": "DerOrthopaede.00290281.eng.abstr-passage-0", "type": "abstract", "text": [ "Any medical procedure must be legally authorized by the patient , giving informed consent . This prerequisite is based on the right to self determination . Otherwise a medical procedure is considered as physical injury . Thus , the way , how a specific procedure is performed , predominantly depends on the patient's will . The attending physician's duty is to find out this will , which is especially important when old patients and patients incapable of giving valid consent are involved . Before the procedure the physician has to have a confidential talk with the patient . He has to point out the best treatment possible considering the individual circumstances of the patient's life . The physician has to find out , weather the patient is competent to refuse or consent to treatement . Furthermore the consultation is an opportunity to diminish the patient's fear and to increase his confidence . The main problem treating old patients is that they often lack the mental ability for appreciation of the nature of the situation . One has to differentiate between the physiological mental decay and dementia or psychiatric diseases . In these cases a third party consent is necessary ." ], "offsets": [ [ 0, 1190 ] ] } ]

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[]

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DerOrthopaede.00290288.eng.abstr

[ { "id": "DerOrthopaede.00290288.eng.abstr-passage-0", "type": "abstract", "text": [ "Femoral neck fractures are frequent fractures of the elderly . They can be treated by the use of dynamic hip screws , lag screws , bipolar hemiprotheses or total hip replacement . The results are markedly influenced by the timing of the operation and the choice of the implant . Using the Garden classification of femoral neck fracture we demonstrate a different therapeutic approach according to Garden stadium I-IV ." ], "offsets": [ [ 0, 418 ] ] } ]

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[]

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DerOrthopaede.00290294.eng.abstr

[ { "id": "DerOrthopaede.00290294.eng.abstr-passage-0", "type": "abstract", "text": [ "Trochanteric fractures frequently occur in elder patients with severe osteopenia . These fractures are highly unstable . Conservative treatment is not indicated because of the long period of immobilisation until fracture healing is achieved . Simple fractures ( A1) can be succesfully fixed by either plate-hip screw systems like Dynamic Hip Screw ( DHS ) or nail-hip screw systems ( Gamma-Nail , Proximal Femur Nail , Classic Nail ) . As a result of biomechanical and clinical trials the intramedullary implants should be prefered for fixation of more comminuted fractures ( Type A2.2, A3.3) and subtrochanteric fractures . For ipsilateral femoral shaft and trochanteric fractures long nail-hip screw-systems are recommended like the long PFN or the long Gamma nail . In about 90 % of the patients with trochanteric fractures postoperative weight bearing can be achieved by internal fixation if gliding systems are applied . Intraoperative and postoperative complications however occur more frequently after the implantation of Gamma-Nail than after application of a DHS . Other implants like Ender Nails , 130 ° angled plate or twisted plate are not further recommended ." ], "offsets": [ [ 0, 1173 ] ] } ]

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[]

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DerOrthopaede.00290302.eng.abstr

[ { "id": "DerOrthopaede.00290302.eng.abstr-passage-0", "type": "abstract", "text": [ "Spinal injuries referring to banal falls are common injuries in elderly persons . Up to 55 years of age spinal fractures are more frequent in men while its opposite in older persons . There are two typical lesions : odontoid fracture in the upper cervical spine and compression fracture in thoracolumbar spine . Odontoid fracture is the most frequent lesion in cervical spine in the elderly . This is caused by trabecular structure of dens axis and spine's stiffness in old age . Instable fractures in extension type II are most common . In many cases the instability of the lesion is hidden and can be first seen in functional examination controlled by x-ray . Conservative treatment is efficient in stable lesions type III while there is a high risk for pseudarthrosis in treatment of instable lesions in elderly with Halo Fixateur e . g . We think that the best operation for these fractures is the anterior screw fixation . If this is not sufficient because of low bone mass or early dislocation of the screws a dorsal fusion C1/C2 with transarticular screwing e . g . should be done . Because of rare symptoms thoracolumbar fractures in osteoporosis are hidden frequently . In many cases it's not easy to distinguish acute lesions from healed fractures or tumor lesions . Neurological deficit is rare . Therefore there are just few compression fractures ( A type ) that have to be treated operatively . Instable lesions type B and C must be operated as well in the elderly as in the young . Because of low bone mass in elderly the dorsal instrumentation should include more than just the two injured segments . An even more adequate stabilisation is done with an additional vertebral replacement ." ], "offsets": [ [ 0, 1702 ] ] } ]

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[]

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DerOrthopaede.00290318.eng.abstr

[ { "id": "DerOrthopaede.00290318.eng.abstr-passage-0", "type": "abstract", "text": [ "Every 15th case of a bone fracture in patients aged more than 65 years concerns the distal radius in Germany . This means the second rank of all geriatric fractures following fractures of the hip . According to the approved and increased apply of operative stabilisation there are arising more and more reports upon poor results of nonsurgical treatment . Especially in older patients the main reason for the discontented outcome of conservative management is osteoporosis , which is an affirmative circumstance for the genesis of fracture but also for secondary malaligment of comminuted thin cortical walls and crushed porotic cancellous bone . The rational of this perception is either filling artificial bonelike tissue - avoiding the need of harvest cancellous bone graft from a second surgical site - into the resultant cavity following reduction , or supplementary transstyloidal or intrafocal K-wiring until remodeling is obtained within an average of 10 weeks . Both arrangements should be secured in addition with a transarticular external fixation . According to a literature review and our own experiences of 92 follow up cases of distal radius fractures in patients who were older than 65 years this procedure seems to be superior at present for A-2, A-3 and most cases of type-C fractures of the distal radius , despite the disadvantage of joint immobilisation for about 5 weeks . Type B-fractures , however , should be provided better with an internal fixation . Sudeck's algodystrophia is the mostly serious complication of the distal radius fracture and its treatment in older patients . Recognising punctually neurovegetative stimulated patients , treat them cautiously and coming in on their special situation is usually the best way to reduce this risk . To pay attention to the topography of the nerves during the application of the pins and to act at the first signs of complications immediately is also very important . We examined 92 patients who were older than 65 years with a fracture of the distal end of the radius in a follow up study . In this group we treated 62 distal radius fractures of the type A and C of the AO classification with an transarticular external fixateur and with supplementary measures if necessary . Additionally we filled the bone cavity with an artificial bone graft ( Endobon ) following closed reduction in 32 cases , 12 times a complementary K-wiring was added and in 8 cases the external fixateur was combined with both . Sudeck's disease appeared in 1.1 % of all cases . In 5 cases we recorded complications with an obligation to treatment as well . Lesion of the superficial branch of the radial nerve were noted in 2 cases ( 2,1 % ) , as far as we extended the surgical approach for the pin application . Technical problems from the site of the external fixateur appeared in 3 cases , two of them could be attributed to an infirmity of the fixateurs ball joints which is now eliminated by the producer . 4 patients with a type-B fracture was provided by plating , additionally 4 patients with a type-C fracture because of non-compliance . The external fixateur is an essential part of a differentiated treatment with reference to the several types of distal radius fractures in older patients ." ], "offsets": [ [ 0, 3255 ] ] } ]

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[]

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DerOrthopaede.00290327.eng.abstr

[ { "id": "DerOrthopaede.00290327.eng.abstr-passage-0", "type": "abstract", "text": [ "In contrast to distal humeral fractures , humeral head fractures represent a common injury to the old patient . For both fracture localizations osteoporosis and multi-morbidity are of significant importance . The classification for humeral head fractures in one- , two- , three- and four-part fractures is generally accepted . Valgus impacted head fractures as well as head-splitting fractures are considered a seperate entity . In none or minimally displaced fractures good functional results are achieved by conservative means . Although numerous therapeutical procdure are offered in the treatment of displaced fractures of the proximal humerus the result are often disappointing . Generally , minimal invasive surgical procedures should be preferred . However , in dislocated multi-part fractures a primary humeral head replacement is often the treatment of choice . In patients with mutifarious morbidity a conservative treatment is always to be included into the therapeutical considerations . Distal fractures of the humerus are classified into extraarticular , intraarticular unicondylar and intraarticular bicondylar fractures . The therapeutical recommendations , also in the elderly , is relatively homogenous : primary open reduction and internal fixation ( ORIF ) should be carried out aiming for an early postoperative functional treatment . Depending from soft tissue conditions and accompanying injuries the functional results are often good or moderate and are generally comparable to those of younger patients . Following a correct indication for surgical intervention the main priority for both distal and proximal humeral fractures is an early definitive surgical treatment ." ], "offsets": [ [ 0, 1695 ] ] } ]

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[]

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DerOrthopaede.00290370.eng.abstr

[ { "id": "DerOrthopaede.00290370.eng.abstr-passage-0", "type": "abstract", "text": [ "Certain fractures and/or dislocations of the femoral head are known to cause arterial injury and result in post-traumatic osteonecrosis . However , the more complex etiology of non-traumatic osteonecrosis is multifactorial and includes chemotherapy , radiotherapy , thermal injuries , and especially coagulopathies , which are now commonly observed in these patients . Intravascular coagulation with fibrin thrombosis begins in the capillaries and sinusoids of the intraosseous microcirculation , and residual venous thrombosis is more likely to occur if there is coexistent hypofibrinolysis ." ], "offsets": [ [ 0, 593 ] ] } ]

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[]

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DerOrthopaede.00290389.eng.abstr

[ { "id": "DerOrthopaede.00290389.eng.abstr-passage-0", "type": "abstract", "text": [ "The pathomorphologies of non-traumatic femoral head osteonecroses ( ON ) are usually similar , despite various known pathogenetic factors . The size and position of the subchondral bone and marrow segment , becoming necrotic after the ischemic event ( s ) , and the kind of repair processes determine the time course and thus the fate of this hip joint disease ." ], "offsets": [ [ 0, 362 ] ] } ]

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[]

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DerOrthopaede.00290403.eng.abstr

[ { "id": "DerOrthopaede.00290403.eng.abstr-passage-0", "type": "abstract", "text": [ "The natural course of Osteonecrosis ( ON ) of the femoral head has yet not been evaluated sufficiently . Especially in the early forms of the disease ( ARCO 0 to II ) without collapse of the femoral head , useful information on the natural course could only be collected since the routine use of MR-imaging . The unspecific findings in ARCO stage I with negative radiographs are potential reversible . The \" point of no return \" already lies in the irreversible ARCO stage II in almost all cases . Prognosis for further progression for both early stages depends primarily on the extension and location of the lesion . Only the rare , small to medium sized lesions in the medial or central location may have a good prognostic course over a period of more than five years . The much more common large sized and lateral located lesions will have a probability of about 80 % to progress to femoral head collapse within two years ." ], "offsets": [ [ 0, 926 ] ] } ]

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[]

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DerOrthopaede.00290411.eng.abstr

[ { "id": "DerOrthopaede.00290411.eng.abstr-passage-0", "type": "abstract", "text": [ "There is still controversy whether transient osteoporosis of the hip joint represents a distinct self-limiting disease , or reflects only an early , reversible subtype of non-traumatic osteonecrosis ( ON ) . Transient osteoporosis has several synonyms : algodystrophy of the hip ; transient marrow oedema ; or bone marrow oedema syndrome - BMOES . Clinical presentation of BMOES shows mechanical hip joint pain , ON risk factors , and a diffuse bone marrow oedema in MR imaging . Histomorphological changes resemble early ON , but with diffuse sufficient repair in BMOES and focal and insufficient repair only at the border of the necrotic lesion in ON . Therefore the clinical course and outcome are significant different , with restitution occurring in BMOES , while progressive destruction of the joint takes place in ON . So far , the preferred treatment strategies are protected weight bearing for BMOES , but operative treatment for ON . In a prospective study of patients with BMOES , the clinical , radiographic , and MRI course of 43 hip joints after core decompression treatment were investigated . All patients showed immediate relief of pain after surgery and the average duration of symptoms with conservative treatment could be dramatically reduced by core decompression from 6 months down to 2 months . There were no perioperative complications . Based on our experience with over 100 BMOES patients , we are convinced that this syndrome represents not a distinct disease but an early reversible subtype of non-traumatic ON . Due to the excellent clinical results of core decompression , we recommend this operative therapeutical concept in patients with painful BMOES ." ], "offsets": [ [ 0, 1685 ] ] } ]

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DerOrthopaede.00290420.eng.abstr

[ { "id": "DerOrthopaede.00290420.eng.abstr-passage-0", "type": "abstract", "text": [ "Core decompression of the necrotic area for treatment of idiopathic osteonecrosis of the femoral head was developed and published by Ficat and Arlet in 1962 within the scope of their \" Functional exploration of bone \" . The mode of action is attributed to a reduction of the intramedullary pressure in the bony compartment of the femoral head . The possibilities of repair and bone regeneration following core decompression are still discussed controversially . Core decompression is a common but not generally accepted procedure in the treatment of idiopathic osteonecrosis of the femoral head . After first publications of positive mid- and long-term effects , some subsequent studies judged it as an ineffective and high-risk method . Analysis of the literature shows that the effectiveness of core decompression depends on the stage of osteonecrosis at the time of surgical intervention . Prognosis is influenced by the extent and location of the necrotic area , the presence and amount of head depression , and continued risk factors - mainly corticoid medication . The best prognosis can be given for patients with a small , medial-centrally located necrosis without head depression ." ], "offsets": [ [ 0, 1190 ] ] } ]

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[]

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"DerOrthopaede.00290420.eng.abstr-s8-r11-t5.1-t2.1", "type": "occurs_in", "arg1_id": "DerOrthopaede.00290420.eng.abstr-s8-t5", "arg2_id": "DerOrthopaede.00290420.eng.abstr-s8-t2", "normalized": [] } ]

DerOrthopaede.00290430.eng.abstr

[ { "id": "DerOrthopaede.00290430.eng.abstr-passage-0", "type": "abstract", "text": [ "The importance of osteotomies in treatment of osteonecrosis of the femoral head has decreased . However , with proper selection of the patient , osteotomies are still useful for small stage III or IV lesions in patients younger than 45 years , and with no ongoing causes for progressive osteonecrosis such as the use of high doses of corticosteroids , chemotherapy , and chronic alcoholism . For preservation of natural hip joint function , the necrotic segment is moved away from the load-transmitting area of the acetabulum , and weight-bearing forces are redistributed to articular cartilage that is supported by healthy bone . In addition to radiographic evaluation , MRI is most accurate for imaging of the stage , localization , and extent of osteonecrosis in planning and selecting osteotomy ." ], "offsets": [ [ 0, 800 ] ] } ]

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[]

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DerOrthopaede.00290442.eng.abstr

[ { "id": "DerOrthopaede.00290442.eng.abstr-passage-0", "type": "abstract", "text": [ "Osteonecrosis of the femoral head remains a devastating disease for young patients . As the normal process of bone formation , bone destruction , and fracture healing becomes more clearly understood , molecular agents - including cytokines , bone morphogenetic proteins , and angiogenic factors - will be identified as potential therapeutic agents for the treatment of osteonecrosis . As the pathology of osteonecrosis and repair of osteonecrotic lesions becomes clear , the potential combination of these molecular factors to influence the outcome of the disease in its repair process should become evident ." ], "offsets": [ [ 0, 609 ] ] } ]

[ { "id": "DerOrthopaede.00290442.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Osteonecrosis" ], "offsets": [ [ 0, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" }, { "db_name": "UMLS", "db_id": "C0027543" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 29, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 56, 63 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 74, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "femoral head" ], "offsets": [ [ 21, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015813" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 110, 114 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 127, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "fracture" ], "offsets": [ [ 150, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016658" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "cytokines" ], "offsets": [ [ 230, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079189" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 242, 246 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "proteins" ], "offsets": [ [ 261, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 329, 340 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 356, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 369, 382 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "bone formation" ], "offsets": [ [ 110, 124 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005939" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "angiogenic factors" ], "offsets": [ [ 276, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002976" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s2-t12", "type": "umlsterm", "text": [ "bone morphogenetic proteins" ], "offsets": [ [ 242, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0053932" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "pathology" ], "offsets": [ [ 392, 401 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205469" }, { "db_name": "UMLS", "db_id": "C0030664" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "osteonecrosis" ], "offsets": [ [ 405, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029445" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 423, 429 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 556, 563 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerOrthopaede.00290442.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "repair" ], "offsets": [ [ 571, 577 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043240" } ] } ]

[]

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DerOrthopaede.00290449.eng.abstr

[ { "id": "DerOrthopaede.00290449.eng.abstr-passage-0", "type": "abstract", "text": [ "In literature , the results of hip arthroplasty in patients with avascular osteonecrosis of the femoral head vary . The main reason may be the nonhomogeneous patient groups concerning etiology of the femoral head necrosis ( FHN ) . Analyzing the results of hip endoprosthesis in relation to the etiology of FHN leads to the assumption that steroid-induced FHN and FHN with underlying systemic bone diseases ( renal osteodystrophy , sickle-cell hemoglobinopathy ) have the highest loosening rates . Diseases with immunosuppressive medication and sickle-cell hemoglobinopathy have the highest risk of joint infection . Therefore etiology plays an important role in the long-term results of hip endoprostheses in FHN . Modern cement techniques of the second generation and new non-cemented total hip endoprostheses seem to have better results than older prostheses and cement techniques . We followed-up 52 non-cemented thrust plate prostheses in 45 patients with FHN , prospectively , for at least 2 years ( 3.7 +/- 1.6 years ) . The revision rate was 9.6 % ( two aseptic loosenings in one patient with renal osteodystrophy and one patient with alcohol abuse , as well as three late infections in one patient with alcohol abuse and two patients with renal osteodystrophy ) . Additionally , five prostheses showed radiologic lines of a minimum of 2 mm . Future studies with longer follow-up are needed to find out whether these prosthetic designs with proximal fixation of the femoral component preserving the diaphysial bone have advantages in young FHN patients ." ], "offsets": [ [ 0, 1562 ] ] } ]

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DerOrthopaede.00290457.eng.abstr

[ { "id": "DerOrthopaede.00290457.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of osteonecrosis of the femoral head involves a continuum based on a radiographic spectrum of disease . Core decompression or pharmacological agents can be utilized for the earliest small or medium-sized pre-collapsed lesions . For these types of lesions , osteotomy has been tried by various authors with moderate success . For small or medium lesions that are post-collapse , various bone grafting procedures have been used . This approach should be tempered with a look at the articular cartilage if this is damaged or the lesion is large . Limited femoral resurfacing can be used for hips that do not have acetabular involvement . If there is acetabular involvement , total hip replacement remains the treatment of choice ." ], "offsets": [ [ 0, 741 ] ] } ]

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[]

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DerOrthopaede.00290490.eng.abstr

[ { "id": "DerOrthopaede.00290490.eng.abstr-passage-0", "type": "abstract", "text": [ "It is generally accepted that the progression of an idiopathic scoliotic deformity with a Cobb angle of between 25 ° and 40 ° can be stopped by brace treatment alone provided that the generally acknowledged criteria for the treatment concerning skeletal growth of the individual are respected ." ], "offsets": [ [ 0, 294 ] ] } ]

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[]

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DerOrthopaede.00290500.eng.abstr

[ { "id": "DerOrthopaede.00290500.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of idiopathic scoliosis over 40 ° ( Cobb ) during the growth period is under discussion concerning the indication for conservative or surgical treatment . Curve progression depends on the degree of the frontal and sagittal deformity , vertebral rotation , rigidity of the curve , the skeletal age , the age and sex of the patient , the familial frequency of scoliosis and the location of the curve . In scoliosis over 40 ° progression is fast and the possibilities for successful conservative brace treatment are reduced during the growth period . Progression occurs more frequently in thoracic and double major scolioses , especially in young patients ( Risser sign 0 and 1 ) ." ], "offsets": [ [ 0, 692 ] ] } ]

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"DerOrthopaede.00290500.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-r1-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290500.eng.abstr-s4-t3", "arg2_id": "DerOrthopaede.00290500.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-r2-t1.1-t2.1", "type": "occurs_in", "arg1_id": "DerOrthopaede.00290500.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290500.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerOrthopaede.00290500.eng.abstr-s4-r3-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290500.eng.abstr-s4-t1", "arg2_id": "DerOrthopaede.00290500.eng.abstr-s4-t3", "normalized": [] } ]

DerOrthopaede.00290507.eng.abstr

[ { "id": "DerOrthopaede.00290507.eng.abstr-passage-0", "type": "abstract", "text": [ "Scoliosis is a complex deformity of the spine with an abnormal shape in all different planes . Purpose of the study is to describe different biomechanical aspects of the operative treatment on the basis of own experimental results and of a review of the literature . The corrective loads , the resistance of the curvature , principles of different implants , the stability of the instrumented spine and problems of implant fixation are discussed . Corrective loads are divided in forces of distraction , compression , translation and rotation . Distraction is more beneficial for severe curvatures ( > 50 ° ) , while transverse load is ideal for milder deformities ( 50 ° ) . Compression is only efficient when applied segmental and anterior . Resistance increases with increasing of the curvature due to the deformation of vertebral bodies . Release is possible anteriorly by open technique or endoscopically and posteriorly by concave thoracoplasty . Principles of different implants are shown : Harrington- ( distraction ) , Luque- ( translation ) , VDS- ( compression , rotation ) , CD- ( combined loading - posterior ) and Kaneda-System ( combined loading - anterior ) . It is possible to perform a primary stable fusion of the spine anterior and posterior . The stability provided by three anterior devices ( VDS , TSRH , CDH ) has been studied in an in-vitro model . TSRH was found to be significantly ( p 0.05 ) higher in stiffness in flexion/extension and torsion than VDS . In bending there was no statistical difference . In all tests CDH was significantly more stable than VDS . In flexion/extension it proved higher in stiffness than TSRH , no statistical difference was observed in bending and rotation . Bone density plays a crucial role in implantfixation , this is more important anterior than posterior . Pedicular screws are superior in their fixational strength than lamina hooks and screws in the vertebral body ." ], "offsets": [ [ 0, 1934 ] ] } ]

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"C0282443" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 254, 264 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "implants" ], "offsets": [ [ 348, 356 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013183" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 393, 398 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "translation" ], "offsets": [ [ 518, 529 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040712" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "rotation" ], "offsets": [ [ 534, 542 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "deformities" ], "offsets": [ [ 653, 664 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220818" }, { "db_name": "UMLS", "db_id": "C0000768" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 733, 741 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "Release" ], "offsets": [ [ 843, 850 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0541720" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "open" ], "offsets": [ [ 877, 881 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0266061" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 882, 891 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": 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"umlsterm", "text": [ "anterior" ], "offsets": [ [ 1163, 1171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "spine" ], "offsets": [ [ 1233, 1238 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037949" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 1239, 1247 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s10-t3", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 1252, 1261 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 1296, 1304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "devices" ], "offsets": [ [ 1305, 1312 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "torsion" ], "offsets": [ [ 1465, 1472 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040480" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s14-t1", "type": "umlsterm", "text": [ "tests" ], "offsets": [ [ 1540, 1545 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s15-t1", "type": "umlsterm", "text": [ "rotation" ], "offsets": [ [ 1708, 1716 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035868" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t1", "type": "umlsterm", "text": [ "Bone" ], "offsets": [ [ 1719, 1723 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t2", "type": "umlsterm", "text": [ "role" ], "offsets": [ [ 1748, 1752 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035820" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t3", "type": "umlsterm", "text": [ "implantfixation" ], "offsets": [ [ 1756, 1771 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021533" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t4", "type": "umlsterm", "text": [ "anterior" ], "offsets": [ [ 1797, 1805 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032008" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t5", "type": "umlsterm", "text": [ "posterior" ], "offsets": [ [ 1811, 1820 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032009" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s16-t6", "type": "umlsterm", "text": [ "Bone density" ], "offsets": [ [ 1719, 1731 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005938" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t1", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 1833, 1839 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t2", "type": "umlsterm", "text": [ "lamina" ], "offsets": [ [ 1887, 1893 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0064635" } ] }, { "id": "DerOrthopaede.00290507.eng.abstr-s17-t3", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 1904, 1910 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] } ]

[]

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DerOrthopaede.00290518.eng.abstr

[ { "id": "DerOrthopaede.00290518.eng.abstr-passage-0", "type": "abstract", "text": [ "The therapy of neuromuscular scolioses has to be tailored to the needs of the individual patient ; there are no universally valid schemes of treatment . Detailed knowledge of neuromuscular diseases and their course is essential ." ], "offsets": [ [ 0, 229 ] ] } ]

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[]

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DerOrthopaede.00290524.eng.abstr

[ { "id": "DerOrthopaede.00290524.eng.abstr-passage-0", "type": "abstract", "text": [ "Spine deformities are a frequent symptom of neurofibromatosis Recklinghausen . Especially NF1 shows next to numerous alterations in the skeleton in some cases massive scoliosis and kyphosis . There are different theories for the development of the spine deformities , one of them is that specific alterations of the vertebra are caused by an elevated intraspinal pressure on the osteoporotic bone . A classification from a clinical point of view discriminates 3 types of severity . Type 1 shows instead of the in x-rays inconspicuous findings neurofibromatosistypical alterations in other diagnostic procedures ( e . g . MRI ) . Extreme variations like short curved scoliokyphosis with massive destruction and severe spine imbalance are described as type 3. Operative treatment is dependent on the severity of the deformity . Intraspinal tumors have to be removed . Because of the elevated neurological risk the proceeding has to be very careful , sometimes there is a temporary Halo-extension necessary . Anterior substance defects are filled with bone or cages . The posterior instrumentation ( in most of the cases a 2-rod-stabilization) is performed by transpedicular screws . Frequently there is a concave chest wall plastic ( CTP ) indicated . To prevent neurological complications early surgical procedure is sometimes necessary . Complications can be reduced by careful proceeding , exact preoperative diagnostic and classification . But next to operative experience a qualified anaesthesiological and intensive care units are absolutely necessary ." ], "offsets": [ [ 0, 1557 ] ] } ]

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[]

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"DerOrthopaede.00290524.eng.abstr-s16-t3", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t1", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s8-r8-t4.1-t3.1", "type": "associated_with", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s15-t4", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t3", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s13-r1-t2.1-t3.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s16-t2", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t3", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s13-r2-t3.1-t2.1", "type": "interacts_with", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s16-t3", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t2", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s14-r1-t3.1-t1.1", "type": "conceptual_part_of", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s16-t3", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t1", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s15-r1-t2.1-t1.1", "type": "affects", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s16-t2", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t1", "normalized": [] }, { "id": "DerOrthopaede.00290524.eng.abstr-s16-r1-t3.1-t1.1", "type": "carries_out", "arg1_id": "DerOrthopaede.00290524.eng.abstr-s16-t3", "arg2_id": "DerOrthopaede.00290524.eng.abstr-s16-t1", "normalized": [] } ]

DerOrthopaede.00290535.eng.abstr

[ { "id": "DerOrthopaede.00290535.eng.abstr-passage-0", "type": "abstract", "text": [ "We report on three years of experience with a new method of a simultaneous endoscopically assisted anterior release in the prone position , combined with transpedicular posterior scoliosis correction and fixation . In 60 cases this simultaneous approach yielded substantial advantages . True derotation of the apex - even in the thoracic spine - is achieved ." ], "offsets": [ [ 0, 359 ] ] } ]

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[]

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DerOrthopaede.00290543.eng.abstr

[ { "id": "DerOrthopaede.00290543.eng.abstr-passage-0", "type": "abstract", "text": [ "The age of standardized instrumented scoliosis correction and stabilization began with Harrington instrumentation ( HI ) . With HI , satisfactory long-term correction of the frontal plane averaged approximately 50 % , but without notable derotational capabilities . The distraction of the concavity leads to reduction of the sagittal contour of the spine ( flat back ) , which is biomechanically disadvantageous . The newer multisegmentally attached implant systems avoid this disadvantage . The first prototypes of these systems were Luque- ( SSI ) and Cotrel-Dubousset instrumentation . Ideal indications for posterior instrumented curve correction are structural idiopathic double major curves and flexible single curves . However , even with these newer doublerod systems derotation is low , because derotation is , without any doubt , related to anterior release and thus decoupling of the segments by means of disc resection ." ], "offsets": [ [ 0, 932 ] ] } ]

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[]

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DerOrthopaede.00290563.eng.abstr

[ { "id": "DerOrthopaede.00290563.eng.abstr-passage-0", "type": "abstract", "text": [ "Halm-Zielke Instrumentation ( HZI ) was developed to eliminate the disadvantage of ventral derotation spondylodesis ( VDS ) - Zielke in terms of lack of primary stability and in order to simplify sagittal plane control . Within a prospective clinical trial started in 1993 , we have studied whether HZI fulfills these demands ." ], "offsets": [ [ 0, 327 ] ] } ]

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[]

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DerOrthopaede.00290571.eng.abstr

[ { "id": "DerOrthopaede.00290571.eng.abstr-passage-0", "type": "abstract", "text": [ "A number of different procedures are used for the surgical treatment of King II scoliosis . One reason for the controversial discussion in this context is that the term King II scoliosis is usually inadequate , because there are partly marked clinical and radiological differences in this type of curvature ." ], "offsets": [ [ 0, 308 ] ] } ]

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[]

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DerOrthopaede.00290605.eng.abstr

[ { "id": "DerOrthopaede.00290605.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of the present study was to increase the free range of motion in conventional trust-plate prosthesis design and to optimize the trust-plate contact as well as the osteointegration area below the trust-plate ." ], "offsets": [ [ 0, 220 ] ] } ]

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[]

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DerOrthopaede.00290614.eng.abstr

[ { "id": "DerOrthopaede.00290614.eng.abstr-passage-0", "type": "abstract", "text": [ "Modern approaches in knee endoprosthetics using computer-assisted navigation systems are based on matching procedures which refer to osseous anatomical landmarks . However , surface replacement techniques require a correct position of the implants in relation to the bone , as well as an optimal postoperative interaction of the ligaments and the surface design of the endoprosthesis . Functional aspects are of elementary importance ." ], "offsets": [ [ 0, 435 ] ] } ]

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[]

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DerOrthopaede.00290627.eng.abstr

[ { "id": "DerOrthopaede.00290627.eng.abstr-passage-0", "type": "abstract", "text": [ "Using CT-based 3D-data of human femora , it is possible to simulate the THR very realistically by a newly developed fit program . The evaluation of OP simulations of different prostheses systems on more than 200 femora showed that a large number of hip joints can only be reconstructed unsatisfactorily by standard stems regarding intramedullary fit and joint geometry . This could be minimized by optimized off-the-shelf prostheses , but there is still a remainder that can only be satisfactorily reconstructed by customized devices . The decision of choosing a standard or custom device for each individual case can be made by the same fit program using CT-data of the femur . Planning with conventional X-rays only shows major restrictions ." ], "offsets": [ [ 0, 744 ] ] } ]

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[]

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