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MundKieferGesichtschirurgie.0004s091.eng.abstr
MundKieferGesichtschirurgie.0004s091.eng.abstr
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MundKieferGesichtschirurgie.0004s103.eng.abstr
MundKieferGesichtschirurgie.0004s103.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s103.eng.abstr-passage-0", "type": "abstract", "text": [ "Functionally stable fixation via bicortical osteosynthesis on the one hand , and monocortical non-compression osteosynthesis on the other , are still two competing concepts in treating mandibular fractures . A survey of the literature shows that complicated fractures with severe dislocation of the fragments have the lowest rate of complications after functionally stable fixation , whereas non-complicated fractures without significant dislocation in the distal part of the mandible can be treated successfully via monocortical non-compressive osteosynthesis as well . It seems that pre- and intraoperative parameters can be helpful in describing the character of a mandibular fracture in order to give a differential indication between the two therapeutical concepts . The consideration of only seven parameters , as the mandibular fracture score does , provides many combinations of describing a fracture , so that former studies with their small number of patients make only a rather inaccurate differential indication possible . As long as there is no prospective multi-center study giving a guideline to classify mandibular fractures , the rigid internal fixation via functionally stable osteosynthesis should be preferred in all cases which are not \" clear , easy to handle \" fractures ." ], "offsets": [ [ 0, 1295 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s110.eng.abstr
MundKieferGesichtschirurgie.0004s110.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s110.eng.abstr-passage-0", "type": "abstract", "text": [ "Among mandibular fractures , those of the condylar neck hold a special position due to the exceptional anatomical situation . Computer assisted tomography and magnetic resonance tomography have improved diagnostic evaluation . Indication for surgical treatment is given in cases of severely displaced or dislocated fractures . In surgical management , the preauricular , submandibular , retromandibular , and oral approach have been established . For sufficient fixation of fragments , procedures rendering a functional stability , like osteosynthesis with lag screw or by miniplating , are required ." ], "offsets": [ [ 0, 601 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s126.eng.abstr
MundKieferGesichtschirurgie.0004s126.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-passage-0", "type": "abstract", "text": [ "The therapy for burn injuries has established a definable management : percentage of the body surface area burned and thickness are important for the method of treatment ( ambulant , on ward , intensive burn center ) . Open and close wound care with different bandages , in combination with primary surgery , has increased the probability of survival . A special problem is the aesthetics and function of the head and neck area . Hypertrophy and keloid scars may be disturbing , especially in children who have had a scald accident ( 41.2% of cases were children up to 5 years of age ) . The possibilities of correction are multiple : conservative therapy ( bandages , ointment treatment , physical therapy ) or surgical intervention with free skin transplantation or difficult flaps ( pedicle flap , free graft , expanded flap , and microvascular anastomosed flap ) . The aim of research is also to cover large defects with skin culture from small donor areas . It is necessary to establish maxillofacial and plastic surgery from the beginning of the treatment for aesthetic and functionally acceptable results ." ], "offsets": [ [ 0, 1113 ] ] } ]
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[]
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"MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-r4-t3.1-t1.1", "type": "uses", "arg1_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t3", "arg2_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-r6-t1.1-t2.2", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-r7-t2.2-t1.1", "type": "uses", "arg1_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s126.eng.abstr-s7-t1", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s134.eng.abstr
MundKieferGesichtschirurgie.0004s134.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s134.eng.abstr-passage-0", "type": "abstract", "text": [ "Gunshot wounds result in a great amount of tissue damage , relating almost always to fractures and defects of the skeleton . The damage varies in relation to the speed , size , shape , and striking angle of the projectile and to the disruption of hard tissue fragments , which multiply the tissue laceration acting as secondary missiles . The rules to be observed in treatment of gunshot wounds are based on experience which was gained during World War I and II . Most of the rules have proved to be a success and may be summarized as follows : approach from inside to outside , preservation of the anatomical relationships of the remaining bony tissues , and primary wound closure . On the other hand , considerable progress has been made concerning reconstruction and establishing a number of new methods in order to create better functional and esthetic results ." ], "offsets": [ [ 0, 866 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s142.eng.abstr
MundKieferGesichtschirurgie.0004s142.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s142.eng.abstr-passage-0", "type": "abstract", "text": [ "Surgery is still the primary therapeutic approach in treatment of tumors in the head and neck area , dating back to the early nineteenth century . More than 150 years ago , hemimaxillectomies and mandibular resections as well as hemiglossectomies were already performed by leading surgeons . The block principle we are now following dates back to Crile , who also established the principle of cervical lymph node dissection . Ablative oncologic surgery has always been closely linked with plastic and reconstructive surgery , rendering radical surgical interventions possible without disfiguring patients . The development of facial reconstructive surgery proceeded in stages , in the first instance as secondary reconstruction using tube pedicled flaps . The change to the concept of primary reconstruction occurred via arterialized skin flaps and myocutaneous flaps to the widely accepted and performed free tissue transfer . Free bone grafting , inaugurated earlier and still representing the majority of bone grafting , has been supplemented for certain reconstructive purposes by free vascularized bone transfer from various donor sites . Although the five-year-survival rate of carcinoma of the oral cavity has remained unchanged in the past 30 years , distinctive improvements in tumor surgery can be recorded . This is primarily based on improved diagnostics such as modern imaging techniques and the refinement of surgical techniques . The DOeSAK has worked out distinctive guidelines for effective ablative oncologic surgery . Surgical approaches offering wide exposure and carrying low morbidity play a decisive role in radical resections . For this reason , midfacial degloving offers an essential improvement for the resection of midface tumors , especially from an aesthetic point of view . Tumors situated deep behind the viscerocranium at the skull base can be clearly exposed either through a lateral approach following a temporary osteotomy of the mandibular ramus or a transmandibular , transmaxillar , or transfacial approach with minimal morbidity . Concerning the concept of neck dissection , radical techniques are more and more abandoned in favor of a more conservative procedure . Actual inquiries concerning present surgical procedures as to the surgical strategy in \" No-neck \" or marginal and segmental resection in mandibular adherent carcinomas demand scientific clarification ." ], "offsets": [ [ 0, 2408 ] ] } ]
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MundKieferGesichtschirurgie.0004s155.eng.abstr
MundKieferGesichtschirurgie.0004s155.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s155.eng.abstr-passage-0", "type": "abstract", "text": [ "Standard curative therapy in head and neck cancer , especially in oral cavity carcinoma , consists , so far , of surgery . Until today , chemotherapy using standard drugs has failed to be effective beyond controlling cancer manifestations and palliation of symptoms . The introduction of chemotherapy and radiotherapy as adjuvant treatment , however , may improve overall survival and curative options . A multicentric randomized trial , initiated by DOeSAK , has compared results after radical surgery alone with results of combined preoperative radio-chemotherapy followed by radical surgery . The life table analysis substantiated improved survival rates in the group of patients whose treatment included chemotherapy and radiation ." ], "offsets": [ [ 0, 736 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s160.eng.abstr
MundKieferGesichtschirurgie.0004s160.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-passage-0", "type": "abstract", "text": [ "Second primary tumors in initially cured patients remain the greatest challenge in therapy for oral squamous cell carcinomas . The concept of field cancerization is the most accepted hypothesis for the cellular and subcellular damages resulting in neoplastic transformation in the upper aerodigestive tract by risk factors such as chronic alcohol and tobacco abuse . Recent studies investigated several agents and regimens with benefit for chemoprevention of oral squamous cell carcinomas . In our review , the results of the most promising agents were studied . Despite discouraging results from recent intervention trials , studies in oral squamous cell carcinomas reported response rates up to 92% . In our investigation , two groups of patients were treated daily with 100 mg -tocopherol , 75 mg -carotene , and 1000 mg ascorbic acid per os . The first group consisted of 24 patients with leukoplakia of the oral cavity . The second group included 24 patients with premalignant lesions after R0-resection of primary oral squamous cell carcinoma . Biopsies were taken from both groups prior to therapy and after 12 weeks follow-up . Flow cytometry analyses were performed and nucleolar organizing regions ( NOR ) were examined . An overall histological response rate of nearly 98% was noticed . Additionally , the pretherapeutic regimen increased cell kinetic parameters , such as the S-phase portion , and the average number of NOR per cell nucleus decreased . These results indicate that the chosen combination has substantial activity in oral premalignant lesions . Nevertheless , basic research is required in investigating valid biomarkers for chemoprevention studies ." ], "offsets": [ [ 0, 1677 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0013146" } ] }, { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "neoplastic transformation" ], "offsets": [ [ 248, 273 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007621" } ] }, { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "risk factors" ], "offsets": [ [ 310, 322 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035648" } ] }, { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "chemoprevention" ], "offsets": [ [ 440, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282515" } ] }, { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 473, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.0004s160.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "carcinomas" 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[]
[]
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MundKieferGesichtschirurgie.0004s169.eng.abstr
MundKieferGesichtschirurgie.0004s169.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-passage-0", "type": "abstract", "text": [ "Basal cell carcinoma is the most frequent skin tumor in humans . It is mostly located in the face and its incidence is steadily rising . The tumor develops from basal , undifferentiated epithelial cells of the skin and its appendices and shows locally destroying growth , but generally without metastatic outspread typical of carcinomas of other origin . The tumor does not occur on the vermilion border of the lips and in the mucosa . Surgery is the most widespread and accepted treatment of basaliomas . It gives the possibility of histologic diagnosis of the whole specimen including margins of resection and allows immediate closure of the defect by means of plastic surgical methods . Regarding aesthetic and functional demands of the region , maxillofacial surgeons have the best prerequisites for this treatment . Recent research results clearly demonstrate the role of UVB light in the etiology , which is modified or promoted by genetic factors . Because of its typical malignant properties , such as progressive growth and infiltration , the term \" basalioma \" , which is mostly used in German , should be replaced by \" basal cell carcinoma \" as it is known in the international literature ." ], "offsets": [ [ 0, 1201 ] ] } ]
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"db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 197, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 210, 214 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "appendices" ], "offsets": [ [ 223, 233 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003617" }, { "db_name": "UMLS", "db_id": "C0496779" } ] }, { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 263, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s3-t6", 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[]
[]
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"location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s9-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s169.eng.abstr-s9-t4", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s187.eng.abstr
MundKieferGesichtschirurgie.0004s187.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s187.eng.abstr-passage-0", "type": "abstract", "text": [ "The clinical symptoms of odontogenic tumors are non-specific . On the roentgenographs one most often sees radiolucencies within the bone , sometimes in combination with scattered or diffuse radioopacities . Root resorptions may be another important feature . After a short historical introduction on the development of today's classification of odontogenic tumors ( WHO ) , each individual type of neoplasm is discussed briefly . Out of this , a therapeutic regime is developed that places each of the 22 entities into one of the following four groups : malignant , locally aggressive , tumors with recurrences , and non-recurrent ones ." ], "offsets": [ [ 0, 637 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s196.eng.abstr
MundKieferGesichtschirurgie.0004s196.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-passage-0", "type": "abstract", "text": [ "Within this chapter , tumors which produce bone matrix ( osteoid ) or other bone-forming tissues , like cartilage , connective tissue , and cementum or originate within the bone marrow are described . In addition , those lesions are mentioned which , according to the WHO , are typical for the jawbones and are therefore included within the 1992 WHO classification of odontogenic tumors . Vascular and epithelial tumors which may also be observed in the jaws are not described . All the lesions and tumors reported have in common a more or less similar clinical and radiological appearance . A precise diagnosis , therefore , can only be established by a sufficient biopsy which should be seen by a pathologist with experience in this field . In addition to clinical , radiological , and histological appearances , therapeutic necessities are described . The data from recent publications are taken into account . This presentation is based on the data collected within the reference registry of the German-Austrian-Swiss Study Group of Tumors of the Face and Jaws ( DOeSAK ) in Basel ." ], "offsets": [ [ 0, 1086 ] ] } ]
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"MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "cementum" ], "offsets": [ [ 140, 148 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011343" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 173, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "marrow" ], "offsets": [ [ 178, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376152" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "bone matrix" ], "offsets": [ [ 43, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005962" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "connective tissue" ], "offsets": [ [ 116, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009780" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "bone marrow" ], "offsets": [ [ 173, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005953" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "classification" ], "offsets": [ [ 350, 364 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008902" }, { "db_name": "UMLS", "db_id": "C0008903" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 380, 386 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "odontogenic tumors" ], "offsets": [ [ 368, 386 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028880" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 413, 419 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "jaws" ], "offsets": [ [ 454, 458 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "epithelial tumors" ], "offsets": [ [ 402, 419 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205853" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "All" ], "offsets": [ [ 479, 482 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023449" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 499, 505 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 602, 611 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "biopsy" ], "offsets": [ [ 666, 672 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 815, 826 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "publications" ], "offsets": [ [ 876, 888 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034036" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "registry" ], "offsets": [ [ 984, 992 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034975" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "Tumors" ], "offsets": [ [ 1037, 1043 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "Face" ], "offsets": [ [ 1051, 1055 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015450" } ] }, { "id": "MundKieferGesichtschirurgie.0004s196.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "Jaws" ], "offsets": [ [ 1060, 1064 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s216.eng.abstr
MundKieferGesichtschirurgie.0004s216.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-passage-0", "type": "abstract", "text": [ "The German-Swiss-Austrian Group on Maxillofacial Tumors ( DOeSAK ) has been performing observational studies in oral cancer . Since 1989 , approximately 1600 cases of tumor of the head and neck per years has been collected in a central tumor registry . The database consists of more than 16,000 patients from 71 clinics ; almost two-thirds are primary cases of squamous cell carcinoma . The data show great differences in patho-anatomical findings , therapy concepts , and five-year survival rates among the hospitals ." ], "offsets": [ [ 0, 519 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Tumors" ], "offsets": [ [ 49, 55 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "cancer" ], "offsets": [ [ 117, 123 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "oral cancer" ], "offsets": [ [ 112, 123 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153381" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 167, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 180, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 189, 193 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 236, 241 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "registry" ], "offsets": [ [ 242, 250 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034975" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "database" ], "offsets": [ [ 257, 265 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242356" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 295, 303 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 370, 374 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 375, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "squamous cell carcinoma" ], "offsets": [ [ 361, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "patho-anatomical" ], "offsets": [ [ 422, 438 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220784" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 439, 447 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 450, 457 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "survival" ], "offsets": [ [ 483, 491 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220921" }, { "db_name": "UMLS", "db_id": "C0038952" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "hospitals" ], "offsets": [ [ 508, 517 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019994" } ] }, { "id": "MundKieferGesichtschirurgie.0004s216.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "survival rates" ], "offsets": [ [ 483, 497 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038954" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s226.eng.abstr
MundKieferGesichtschirurgie.0004s226.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-passage-0", "type": "abstract", "text": [ "Distraction osteogenesis is established worldwide as a new surgical technique . The former rule , not to osteotomise before the end of bone growth , is no longer valid . Today , distraction starts as early as infancy as well as in childhood and adolescence . This new method allows the gain of bone in the distraction gap so that bone grafting can be avoided . Distraction is indicated in hemifacial microsomias , multiple syndromes with mandibular malformations , mandibular retrognathia , posttraumatic jaw deficiencies , craniofacial malformations , alveolar ridge resorptions , and alveolar ridge resections . Distraction surgery started in the mandible and was continued in the maxilla and the craniofacial region . Alveolar ridge distraction followed . After using extraoral devices , the development of internal applicable distractors followed . Today , bi- or tridirectional internal devices are already available . The whole treatment concept includes the orthodontist . Distraction planning before surgery is of great importance . The literature presently includes methods , indications , and case reports but only few results , which we compare with our experiences ." ], "offsets": [ [ 0, 1178 ] ] } ]
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"C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 140, 146 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "adolescence" ], "offsets": [ [ 245, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001578" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 268, 274 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 294, 298 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 330, 334 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "grafting" ], "offsets": [ [ 335, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040732" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "bone grafting" ], "offsets": [ [ 330, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005976" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "syndromes" ], "offsets": [ [ 423, 432 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "malformations" ], "offsets": [ [ 449, 462 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0243070" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "retrognathia" ], "offsets": [ [ 476, 488 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035353" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 505, 508 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "deficiencies" ], "offsets": [ [ 509, 521 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011155" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "malformations" ], "offsets": [ [ 537, 550 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0243070" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "alveolar ridge" ], "offsets": [ [ 553, 567 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0447411" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "alveolar ridge" ], "offsets": [ [ 586, 600 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0447411" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 626, 633 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 649, 657 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "maxilla" ], "offsets": [ [ 683, 690 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024947" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "Alveolar ridge" ], "offsets": [ [ 721, 735 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0447411" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "devices" ], "offsets": [ [ 781, 788 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 795, 806 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "devices" ], "offsets": [ [ 892, 899 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 934, 943 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "planning" ], "offsets": [ [ 992, 1000 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 1008, 1015 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 1045, 1055 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 1075, 1082 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s226.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "case reports" ], "offsets": [ [ 1103, 1115 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007320" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s237.eng.abstr
MundKieferGesichtschirurgie.0004s237.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s237.eng.abstr-passage-0", "type": "abstract", "text": [ "The article reviews the history of orthognathic surgery from the middle of the last century up to the present . Initially , mandibular osteotomies were only performed in cases of severe malformations . But during the last century a precise and standardized procedure for correction of the mandible was established . Multiple modifications allowed control of small fragments , functionally stable osteosynthesis , and finally a precise positioning of the condyle . In 1955 Obwegeser and Trauner introduced the sagittal split osteotomy by an intraoral approach . It was the final breakthrough for orthognathic surgery as a standard treatment for corrections of the mandible . Surgery of the maxilla dates back to the nineteenth century . B. von Langenbeck from Berlin is said to have performed the first Le Fort I osteotomy in 1859. After minor changes , Wassmund corrected a posttraumatic malocclusion by a Le Fort I osteotomy in 1927. But it was Axhausen who risked the total mobilization of the maxilla in 1934. By additional modifications and further refinements , Obwegeser paved the way for this approach to become a standard procedure in maxillofacial surgery . Tessier mobilized the whole midface by a Le Fort III osteotomy and showed new perspectives in the correction of severe malformations of the facial bones , creating the basis of modern craniofacial surgery . While the last 150 years were distinguished by the creation and standardization of surgical methods , the present focus lies on precise treatment planning and the consideration of functional aspects of the whole stomatognathic system . To date , 3D visualization by CT scans , stereolithographic models , and computer-aided treatment planning and simulation allow surgery of complex cases and accurate predictions of soft tissue changes ." ], "offsets": [ [ 0, 1812 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s249.eng.abstr
MundKieferGesichtschirurgie.0004s249.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-passage-0", "type": "abstract", "text": [ "Endosseous osseointegrated implants have become an integral part of the treatment scheme for the prosthetic reconstruction and rehabilitation of masticatory function following scientific studies of the reactions between implant and soft and hard tissues . Furthermore , implants offer good chances for prosthetic rehabilitation in the insufficient bone site , if the extremely atrophic jaw is to be reconstructed by grafting procedures with avascular and vascular grafts , by guided bone regeneration , by distraction osteogenesis , by bone substitutes and in the future by osteoinductive proteins in order to prepare the conditions for implant insertion . Those reconstruction procedures combined with implants become often necessary , if complicated hard and soft tissue defects of the skull have to be reconstructed to create the prerequisites for the stabilisation of epitheses or to insert implant-supported devices ." ], "offsets": [ [ 0, 922 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0005972" } ] }, { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-s2-t14", "type": "umlsterm", "text": [ "distraction osteogenesis" ], "offsets": [ [ 506, 530 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524975" } ] }, { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-s2-t15", "type": "umlsterm", "text": [ "bone substitutes" ], "offsets": [ [ 536, 552 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243003" } ] }, { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 678, 688 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "hard" ], "offsets": [ [ 752, 756 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018599" } ] }, { "id": "MundKieferGesichtschirurgie.0004s249.eng.abstr-s3-t3", 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[]
[]
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MundKieferGesichtschirurgie.0004s257.eng.abstr
MundKieferGesichtschirurgie.0004s257.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s257.eng.abstr-passage-0", "type": "abstract", "text": [ "This paper describes preprosthetic surgery from its historical beginnings to its present state-of-the-art status . Future perspectives of preprosthetic surgery are also outlined , excluding implants . In an enquiry of 250 German-speaking maxillofacial departments , 160 responded . Results showed that a surprising 30-50% of the institutions are still following guidelines for procedures which have been proven by scientific follow-up studies to be almost 100% unsuccessful ." ], "offsets": [ [ 0, 475 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s265.eng.abstr
MundKieferGesichtschirurgie.0004s265.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s265.eng.abstr-passage-0", "type": "abstract", "text": [ "The first publications in dentoalveolar surgery date back to the eighteenth century , while basic works in German-speaking areas appeared in the first half of the 20th century . Dentoalveolar surgical issues are still present within craniomaxillofacial surgery nowadays . Nomenclature has changed little while contents in certain areas shift away from surgical practical aspects towards biological-medical points of view . The new technologies of dentoalveolar surgery are being developed for maximal patient safety using minimal invasive methods . Other , traditionally non-surgical , dental subspecialities are taking over dentoalveolar surgical issues . Oral surgery remains a part of craniomaxillofacial surgery and should continue to get a major boost from it in the future ." ], "offsets": [ [ 0, 780 ] ] } ]
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[]
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MundKieferGesichtschirurgie.0004s270.eng.abstr
MundKieferGesichtschirurgie.0004s270.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s270.eng.abstr-passage-0", "type": "abstract", "text": [ "A vital X-ray imaging technique in oral and craniomaxillofacial surgery is the panoramic X-ray . Due to its variety of special projections , including imaging of the transversal level and low exposure to radiation , it is suitable for answering many clinical questions and for diagnostics of various findings . It has become possible to minimize the necessary doses by further development of technology and devices , as well as of X-ray films and by new detection systems , such as sensors or screens . In some clinical cases , the diagnostic deficiencies of conventional imaging techniques make computed tomography ( CT ) and magnetic resonance ( MR ) imaging indispensable . Although MR is particularly suitable for soft tissue imaging , it has also become helpful in finding cortical changes by shorter measuring times . In certain cases , e . g . , changes to bone metabolism , differentiated methods of nuclear medicine make image-aided analysis of function possible ." ], "offsets": [ [ 0, 973 ] ] } ]
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MundKieferGesichtschirurgie.0004s286.eng.abstr
MundKieferGesichtschirurgie.0004s286.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-passage-0", "type": "abstract", "text": [ "While facial and craniofacial deformities and facial trauma comprise considerable amounts of bony surgery , the treatment of facial skin tumours requires essentially different approaches and skills of soft tissue surgery of the surface . Although the speciality of maxillofacial surgery developed during the World Wars in Europe , soft tissue reconstruction of the face has been greatly refined since then . A table of ten reconstructive principles is further elucidated in the text followed by 17 clinical examples , from the scalp to various areas of the face to the lips . As aesthetics play a dominant role in facial reconstruction , local flaps are the first choice , while pedicled flaps from the chest or microvascular free flaps are only considered for otherwise too-large defects . Only very few exceptions exist to this rule ." ], "offsets": [ [ 0, 836 ] ] } ]
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"MundKieferGesichtschirurgie.0004s286.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 132, 136 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "tumours" ], "offsets": [ [ 137, 144 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 206, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 213, 220 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "skin tumours" ], "offsets": [ [ 132, 144 ] ], "normalized": [ { 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"associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-r31-t7.1-t5.1", "type": "surrounds", "arg1_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t7", "arg2_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-r32-t1.1-t2.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s286.eng.abstr-s4-t2", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s306.eng.abstr
MundKieferGesichtschirurgie.0004s306.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-passage-0", "type": "abstract", "text": [ "After a short description of the history of eyelid reconstruction , the causes of defects are discussed . For the primary and secondary treatment of thermic injuries , a full-skin graft is recommended and the indication of combined skin-cartilage transplants is mentioned . For deep defects , numerous methods of eyelid reconstruction are available . The differentiated indication for manifold initial situations is discussed in detail . The most important techniques are described on the basis of various examples ." ], "offsets": [ [ 0, 516 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "history" ], "offsets": [ [ 33, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019664" }, { "db_name": "UMLS", "db_id": "C0019665" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "eyelid" ], "offsets": [ [ 44, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015426" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "causes" ], "offsets": [ [ 72, 78 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 82, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "secondary" ], "offsets": [ [ 126, 135 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" }, { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 136, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "injuries" ], "offsets": [ [ 157, 165 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175677" }, { "db_name": "UMLS", "db_id": "C0021501" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "graft" ], "offsets": [ [ 180, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "transplants" ], "offsets": [ [ 247, 258 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 283, 290 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 302, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "eyelid" ], "offsets": [ [ 313, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015426" } ] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 457, 467 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] } ]
[]
[]
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}, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r6-t4.2-t3.2", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r7-t4.2-t1.2", "type": "surrounds", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r8-t1.2-t3.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r9-t1.1-t4.2", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r10-t2.1-t3.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r11-t2.1-t1.2", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r12-t1.2-t1.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r13-t1.2-t4.2", "type": "developmental_form_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": 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"arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r18-t4.2-t1.2", "type": "developmental_form_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r19-t4.2-t1.2", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r20-t4.2-t2.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r21-t1.2-t3.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r22-t4.2-t1.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r23-t1.1-t3.2", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r24-t1.1-t1.2", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r25-t1.1-t2.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r26-t1.2-t2.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s3-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-r27-t1.2-t4.2", "type": "surrounds", "arg1_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s306.eng.abstr-s2-t4", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s314.eng.abstr
MundKieferGesichtschirurgie.0004s314.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s314.eng.abstr-passage-0", "type": "abstract", "text": [ "Skin grafting is one of the earliest described surgical procedures . In the age of microsurgery and free-tissue transfer , it remains a utilitarian means of achieving soft tissue reconstruction . Free skin grafts can be classified into three types : full-thickness skin grafts , split-thickness skin grafts , and composite grafts . The indications , techniques , donor site considerations , postoperative complications , and results of each type are reviewed . The full-thickness skin graft for facial and cervical reconstruction is usually harvested from the upper arm or postauricular region and is applied under a tie-over dressing . When comparing the functional and aesthetic results of full-thickness skin grafts and split-thickness skin grafts in terms of morbidity , skin elasticity , skin sensitivity , matching , and scar recurrence , full-thickness skin grafting seems to be the most adequate technique ." ], "offsets": [ [ 0, 915 ] ] } ]
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[]
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MundKieferGesichtschirurgie.0004s322.eng.abstr
MundKieferGesichtschirurgie.0004s322.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s322.eng.abstr-passage-0", "type": "abstract", "text": [ "Microvascular bone transplantation has become a routine procedure . The iliac crest , scapula , and fibula are the most common donor sites . These are used for reconstruction of tumor-related defects or after osteoradionecrosis . But additional indications have been developed as defects after trauma , extreme atrophy , or hemifacial microsomia . In the future , three-dimensional techniques will improve transplantation surgery and will enable the prefabrication of transplants ." ], "offsets": [ [ 0, 481 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s331.eng.abstr
MundKieferGesichtschirurgie.0004s331.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-passage-0", "type": "abstract", "text": [ "Micronervereconstruction of motor and sensitive nerves in the head and neck area today has an established range of indications . Surgical procedures of external and internal neurolyses , nerve coaptation and nerve transplantation techniques are well standardized . With microneurosurgery of motor nerves , satisfying or good results can be generally obtained . Success rates exceeding 50% following sensitive nerve reconstructions justify the performance of the procedures , more so because of the subjective improvements for the individual patient . Perspectives can be seen in further simplification of surgical methods of harvesting nerve grafts , e.g. , by development of minimally invasive , eventually endoscopically guided procedures . Allogenic nerve grafts may also be applied . Initial experiments with nerve distractions are encouraging . A better understanding of nerve lesions on cellular and molecular biological levels may improve our knowledge of posttraumatic regulatory procedures and may lead to future possibilities of nonsurgical treatment options for peripheral and central nerve lesions by guided regeneration ." ], "offsets": [ [ 0, 1134 ] ] } ]
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"MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-r34-t6.1-t8.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t8", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-r35-t5.1-t2.1", "type": "measurement_of", "arg1_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t5", "arg2_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-r36-t7.2-t4.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t7", "arg2_id": "MundKieferGesichtschirurgie.0004s331.eng.abstr-s8-t4", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s352.eng.abstr
MundKieferGesichtschirurgie.0004s352.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-passage-0", "type": "abstract", "text": [ "Pain therapy in the oral and maxillofacial region is still a problem . Before starting therapy , the genesis of pain has to be carefully clarified . The article presents the most important syndromes , aspects concerning diagnosis and differential diagnosis as well as therapeutic schemata ." ], "offsets": [ [ 0, 290 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Pain" ], "offsets": [ [ 0, 4 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030193" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 5, 12 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "Pain therapy" ], "offsets": [ [ 0, 12 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002766" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 87, 94 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "pain" ], "offsets": [ [ 112, 116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030193" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "syndromes" ], "offsets": [ [ 189, 198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 220, 229 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 247, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 268, 279 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "MundKieferGesichtschirurgie.0004s352.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "differential diagnosis" ], "offsets": [ [ 234, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220820" }, { "db_name": "UMLS", "db_id": "C0011906" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s356.eng.abstr
MundKieferGesichtschirurgie.0004s356.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-passage-0", "type": "abstract", "text": [ "Content of this paper is the current state of the art of robots in surgery and the ongoing work on the field of surgical robotics at the Clinic for Maxillofacial Surgery at the Charité . Robots in surgery allows the surgeon to transform the accuracy of the imaging systems directly during the intervention and to plan an intervention beforehand . In this paper firstly the state of the art is described . Subsequently the scientific work at the clinic is described in detail . The paper closes with a outlook for future applications of robotics systems in maxillofacial surgery ." ], "offsets": [ [ 0, 579 ] ] } ]
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[]
[]
[ { "id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-r1-t3.2-t7.2", "type": "method_of", "arg1_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-t3", "arg2_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-r2-t1.1-t7.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-r3-t1.1-t3.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s5-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-r4-t2.1-t7.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s5-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s356.eng.abstr-s1-t7", "normalized": [] }, { 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MundKieferGesichtschirurgie.0004s369.eng.abstr
MundKieferGesichtschirurgie.0004s369.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s369.eng.abstr-passage-0", "type": "abstract", "text": [ "The exponential increase of medical information creates a need for new methods in the visualization of medical imaging modalities for diagnosis and therapy . In this sense , visualization includes the display of medical image data and image-guided stereotaxic navigation as well as the advice of an expert . The Artma Virtual Patient System enables a remote expert to observe the surgical procedure via the Internet and interactively modify the interoperative visualization from the remote location . The expert in the remote location receives the planning data almost in real time over TCP/IP from a stereotaxic videoserver . In addition to live video streaming , stereotaxic navigation data are sent over the network as rigid body coordinates . The expert modifies the surgical simulation on the remote computer and the modified operating plan is sent back to the operating site . By teleconsulting , the composite images and overlapping graphics -instruments , target structures , landmarks , contour - can be seen in affiliated clinics with the possibility of interactive graphical assistance . With this image fusion technology the knowledge of a remote expert is included in virtual data structures and visualized by the overlay with live video data ( augmented reality ) in real time during surgery ." ], "offsets": [ [ 0, 1307 ] ] } ]
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[]
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"arg1_id": "MundKieferGesichtschirurgie.0004s369.eng.abstr-s8-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s369.eng.abstr-s8-t1", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s375.eng.abstr
MundKieferGesichtschirurgie.0004s375.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s375.eng.abstr-passage-0", "type": "abstract", "text": [ "Ultrasonography has gained acceptance in maxillofacial surgery as a first-choice diagnostic tool in soft tissue masses of the head and neck . To date , A-mode sonography of the maxillary sinus is only performed in children and pregnant women . However , B-mode sonography is primarily performed in the assessment of all cervical lymph nodes because of its superior sensitivity in comparison to CT and MR , as well as in diseases of the salivary glands , solid tumors , and monitoring of distraction osteogenesis of the mandible . With color-coded ultrasonography as a combination of B-mode and blood flow information , vessels of the head and neck area or of planned flaps can be examined in a noninvasive manner . This is especially important in secondary microsurgical reconstructions . Moreover , the blood flow in any soft tissue masses can be evaluated . In spite of all texture and image analysis techniques , positive and negative lymph nodes cannot be differentiated in a safe manner . Three-dimensional sonography , e . g . , panoramic pictures , and contrast enhancement are new technologies that will improve diagnostic accuracy of head and neck ultrasonography ." ], "offsets": [ [ 0, 1174 ] ] } ]
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MundKieferGesichtschirurgie.0004s401.eng.abstr
MundKieferGesichtschirurgie.0004s401.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s401.eng.abstr-passage-0", "type": "abstract", "text": [ "After more than 25 years of activity in the field of salivary gland surgery , especially parotid gland surgery , the following statements can be made . 1. Salivary gland diseases are extremely variable and their treatment requires vast clinical experience . 2. The judgement of salivary gland diseases requires highly competent pathologic assistance and a specialized laboratory in this respect . In the field of salivary gland pathology - like in many other specialized subdivisions in pathology - the need of a second opinion in order to increase the reliability of the original diagnosis has to be claimed once more . 3. A certain change has taken place in the diagnostic means . Modern techniques of visualization show a shift toward noninvasive sonography , but also toward computed tomography with or without contrast agents , and there is a steadily increasing shift toward magnetic resonance tomography as well . 4. The literature about salivary gland diseases and their therapy can no longer be overlooked and is unfortunately characterized by very different aspects of judgement , which in many cases hardly allow a comparative discussion of certain clinical and therapeutic questions . 5. Parotid gland surgery requires a clear concept concerning the different diseases , especially of the different oncologic entities . Surgical preparation of the facial nerve has to be mastered equally from the central and the peripheral course of the nerve ." ], "offsets": [ [ 0, 1457 ] ] } ]
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[]
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MundKieferGesichtschirurgie.0004s423.eng.abstr
MundKieferGesichtschirurgie.0004s423.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-passage-0", "type": "abstract", "text": [ "The potential of distraction osteogenesis in mandibular reconstruction has been limited by its questionable efficacy in previously irradiated bone . The possible osteogenetic effect of recombinant human basic fibroblast growth factor ( bFGF ) on lengthening of irradiated mandibles was investigated in beagle dogs . We studied nine adult dogs which underwent a full course of external beam radiation therapy ( 60 Gy/30 fractions ) . Six months after completion of radiotherapy , the molars were extracted bilaterally followed by bone lengthening of the mandible using an intraoral device . On postoperative day 3 and 7 we injected 10 µg bFGF into the osteotomy site of each right hemimandible . The left sides were used as controls . The time course in ossification of the distracted area was evaluated at 2 , 4 , and 6 weeks after completion of bone lengthening . The radiographs of the newly formed bone tissue were measured by digital image analysis . Corresponding to the radiographic findings , the histological examination of the removed jaws showed an earlier and more intensive bone formation in the treated side after 2 , 4 , and 6 weeks compared to the control side . We conclude that bFGF promotes the ossification of distracted mandibles after radiation therapy in dogs ." ], "offsets": [ [ 0, 1283 ] ] } ]
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"C0016030" } ] }, { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 220, 226 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "bFGF" ], "offsets": [ [ 236, 240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004805" } ] }, { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "mandibles" ], "offsets": [ [ 272, 281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "dogs" ], "offsets": [ [ 309, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012984" } ] }, { "id": "MundKieferGesichtschirurgie.0004s423.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "growth factor" ], "offsets": [ [ 220, 233 ] ], 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MundKieferGesichtschirurgie.0004s428.eng.abstr
MundKieferGesichtschirurgie.0004s428.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s428.eng.abstr-passage-0", "type": "abstract", "text": [ "In order to restore function and esthetics in mandibular hypoplasia , transplantation of osteochondral grafts and the distraction osteogenesis technique are used alternatively . In a retrospective study the indication , growth and complication rate of osteochondral graft and distraction osteogenesis cases in mandibular hypoplasia were compared . In total , 12 patients ( 4-14 years old ; 7 female , 5 male ) with different grades of mandibular hypoplasia received osteochondral grafts ( 7 costochondral , 5 iliac crest ; observation period 4-9 years ) . In 5 patients ( 10-12 years old ; 1 female , 4 male ) , distraction osteogenesis was performed ( observation period 10 months to 3 1/2 years ) . In the results , according to the literature , the range of growth after osteochondral grafting varied considerably , approximate normal growth was noticed in only two cases . On the other hand , all patients treated by distraction osteogenesis showed a stable increase of bone length as expected . After osteochondral grafts , adequate growth is to be expected in the minority of cases and it does not seem predictable in individual cases . Therefore , the indication for osteochondral grafts should be restricted to severe hypoplasia , where the local amount of bone does not allow the use of a distraction device , and to cases where support of the mandibula at the skull base is necessary . In all other cases of mandibular hypoplasia in children , distraction osteogenesis should be discussed as the primary option , even if in the long term a second surgical procedure should be necesssary ." ], "offsets": [ [ 0, 1598 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s432.eng.abstr
MundKieferGesichtschirurgie.0004s432.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s432.eng.abstr-passage-0", "type": "abstract", "text": [ "Vertical distraction osteogenesis ( VDO ) has been developed by our study group to move dentulous and edentulous segments of the alveolar process vertically with a device in microplate-design . Besides these techniques of vertical distraction of the atrophic alveolar crest some further modifications as Micro- and Macrodistraction are available . Microdistraction can be used in localised small defects of the alveolar crest with microplates and screws of 1.0 mm in diameter . In a pilotstudy we could treat 6 patients especially after traumatic bone loss of the alveolus . The lengths of the segments were 12.6 mm , the vertical distraction rate was 9.2 mm in average . Macrodistraction we call the distraction of the severely resorbed mandible in order to rebuild the vertical dimension of the weakened mandible . Vertical distraction osteogenesis of 13.6 mm was completed successfully in five patients with large segments of 119 mm lengths in average in a sandwich-technique . With a solid 2.3 basic plate a secure stability of the weakened mandible could be achieved . In contrast to bone transplantation an earlier mineralisation in the vertically distracted area could be seen by radiological examination and biopsy . We could insert dental implants in both pilot groups 3 months after distraction procedure . Main advantages of vertical distraction osteogenesis are : 1. No bone harvesting , 2. decreased resorption , 3. lower morbidity compared with conventional techniques , 4. lower infection rate and 5. feasibility to insert dental implants 3 months after distraction procedure , 6. gain of soft tissue ." ], "offsets": [ [ 0, 1617 ] ] } ]
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[]
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"MundKieferGesichtschirurgie.0004s432.eng.abstr-s11-r20-t2.1-t8.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.0004s432.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s432.eng.abstr-s11-t8", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s438.eng.abstr
MundKieferGesichtschirurgie.0004s438.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s438.eng.abstr-passage-0", "type": "abstract", "text": [ "Total or partial relapses after conventional surgical advancement of the maxilla following Le Fort I osteotomy in CLP patients are frequent and major complications . The aim of this investigation was to find out whether the technique of distraction osteogenesis in these patients shows more stability and whether maxillary distraction is able to replace conventional advancement . Maxillary distraction was performed in 12 patients . In two cases , a Delaire mask was used to bring the maxilla forward , ten patients were treated with the extraoral distraction device designed by Polley . In all patients , planned advancement of the maxilla could be achieved ; one partial relapse occurred . The results indicate that distraction osteogenesis offers the possibility of advancement of the maxilla with the required stability . The technique presents a major improvement which is achieved with a relatively minor surgical procedure ." ], "offsets": [ [ 0, 932 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s442.eng.abstr
MundKieferGesichtschirurgie.0004s442.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s442.eng.abstr-passage-0", "type": "abstract", "text": [ "Callus distraction in the treatment of severe midfacial hypoplasia/atrophy may offer new therapeutical possibilities . Between May 1998 and March 1999 , six patients underwent a subtotal Le Fort I-II osteotomy with subsequent distraction via a haloborne distractor ( RED ) . Five patients suffered from CLP , four patients were totally or almost edentulous in the upper jaw . Corrections of sagittal discrepancies were possible in all cases ( distraction 16-31 mm ) . No case of increased velopharyngeal insufficiency was seen . In one patient the halo had to be refixed . Three patients suffered from tension-like pain in the soft palate during distraction . Follow-up studies suggest the necessity for overcorrection of 20% in edentulous senior patients . Callus midfacial distraction is a promising new alternative to conventional orthognathic surgery in severe cases ." ], "offsets": [ [ 0, 872 ] ] } ]
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MundKieferGesichtschirurgie.0004s446.eng.abstr
MundKieferGesichtschirurgie.0004s446.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s446.eng.abstr-passage-0", "type": "abstract", "text": [ "Gradual callus distraction in the correction of hypoplastic areas in the viscerocranial skeleton is an established method due to its efficacy . Whereas functional and esthetical improvements can be seen easily , it is impossible to get the increase of the bony mass right using the distractor scale or by clinical investigation . Only in animal studies can volumetric and densitometric measurements be done directly . By permission of the local ethics commission , in a clinical study , CT data of 24 children ( 12 unilateral and bilateral hypoplasias each ) taken before and after mandibular distraction osteogenesis were used to get information on the amount of created bone and the grade of ossification of the callus at the time of the distractor removal . The CT data were prepared for computer evaluation using software which had been especially developed for this investigation . The quality of the investigation was influenced by disturbed data acquisition ( insufficient sedation , Gantry deviation , different axial cuts ) . Therefore , the estimation of the real increase of bone was not possible , but all in all an increase of the volume could be seen . Using a grey scale analysis , the grade of new bone ossification was over 90% at the time of distractor removal . In our opinion , these results argue against the use of CT scans for the validation of a mandibular distraction . The estimation of the volume is very imprecise , the grade of ossification of the new bone very constant ." ], "offsets": [ [ 0, 1501 ] ] } ]
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MundKieferGesichtschirurgie.0004s454.eng.abstr
MundKieferGesichtschirurgie.0004s454.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s454.eng.abstr-passage-0", "type": "abstract", "text": [ "The purpose of this study was to construct a vascularized bone graft using the osteoinductive bone morphogenetic protein ( rh-BMP-2), a polylactic acid matrix ( OPLA/HY ) , and a vascularized periosteal flap containing osteoprogenitor cells ectopically in the groin or orthotopically in a femoral defect . In the Lewis rat , periosteal flaps were harvested from the medial surface of the tibia vascularized by the saphenous artery and vein and were transferred to the groin on its vascularized pedicle . Alternatively , the periosteal flap along its pedicle was transferred between the thigh muscles to be wrapped around a femoral defect of 1 cm . The animals were divided into 10 groups ( 82 animals ) . In group 1 , the periosteal flap was left empty in the groin . Groups 2 and 3 consisted of the periosteal flap and 20 µg rh-BMP-2, but in group 3 the vascular pedicle was ligated proximally . In group 4 the flap was harvested without the periosteal layer and turned \" inside out \" . Groups 5 and 6 consisted of the periosteal flap and the matrix OPLA/HY +/- 20 µg rh-BMP-2. In the femoral defect model , bone formation was studied using the matrix OPLA/HY alone ( group 7 ) or combined with the vascularized periosteal flap ( group 8 ) , or in combination with OPLA/HY+BMP ( group 9 ) or OPLA/HY+BMP+the periosteal flap ( group 10 ) . The presence and density of new bone formation in the groin and femoral defect were evaluated radiologically and histologically at 4 and 8 weeks . Good bone formation in the groin chamber ( ectopic ) was demonstrated in the periosteal flap + OPLA/HY + BMP group . In the femoral defects , good bone formation ( orthotopic ) was seen in the OPLA/HY + BMP + the periosteal flap groups . However , with the presence of a vascularized periosteal flap , more bone formation along the rim of the defect was observed . This study of ectopic bone formation in the groin and orthotopic bone formation in the femoral defect demonstrates that optimal bone formation requires four factors : BMP , a biodegradable matrix , osteoprogenitor cells , and blood supply . Potentially in the future , this technique could be used to reconstruct a bony defect or a nonunion by covering the involved area with a vascularized periosteal flap and a suitable matrix combined with BMP . Alternatively , a vascularized bone graft could be prefabricated at a distant site and then transferred microsurgically into a defect ." ], "offsets": [ [ 0, 2436 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s459.eng.abstr
MundKieferGesichtschirurgie.0004s459.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s459.eng.abstr-passage-0", "type": "abstract", "text": [ "Autolyzed , antigen-extracted , allogenic ( AAA ) bone is an osteoinductive preparation of completely demineralized bone matrix . It has been clinically applied for years . In an experimental study in rabbits , we evaluated the influence of cortical bone and periosteum on the amount of bone formation following augmentation with AAA bone . Two implants of standardized size were placed on the femoral bone of rabbits . A cell-excluding PTFE membrane was wrapped circularly around the femur as well as the anterior implant shielding the implant from the surrounding periosteum . The posterior implant was exposed directly to the periosteum while being shielded from the cortical bone by the membrane . Thus , two compartments were created selectively , preventing contact between the periosteum or cortical bone and the implants . For each compartment the area and volume of the induced new bone were evaluated by computerized radiograph analysis and quantitative CT ( pQCT ) scans . Implantation of AAA bone led to new bone formation in both compartments . Contact of the periosteum and the implant led to an almost fourfold increase in bone volume . Although bone formation showed interindividual variations , the difference of both compartments was highly significant using the Student's t-test for paired samples ( P 0.0001 ) . The data show that periosteum is the primary source of new bone formation in augmentations with osteoinductive materials as it is rich in inducible progenitor cells and is well vascularized . In osseous augmentations with AAA bone , the periosteum should be preserved in order to achieve a close contact of the osteoinductive implant . Shielding from the periosteum , e.g. , by cell-excluding membranes , leads to significantly less bone formation following implantation of AAA bone and should therefore be avoided ." ], "offsets": [ [ 0, 1848 ] ] } ]
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[]
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MundKieferGesichtschirurgie.0004s474.eng.abstr
MundKieferGesichtschirurgie.0004s474.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s474.eng.abstr-passage-0", "type": "abstract", "text": [ "The aim of the present study was to test polylactic acid material as a controlled release carrier for polypeptide growth factors . Basic fibroblast growth factor ( bFGF ) was incorporated into DL polylactic acid ( PLA ) pellets under hyperbaric CO2 pressure in two different ways . ( 1 ) Lyophilized bFGF was crushed and mixed with PLA granules , filled into cylindric moulds of 5 x 3 mm , and submitted to hyperbaric CO2 pressure . ( 2 ) Lyophilized bFGF was reconstituted in phosphate buffer , mixed with PLA granules , and relyophilized . In vitro assessment of bFGF release from the PLA implants by immunoassay showed that loading of PLA with crushed lyophilized bFGF resulted in a rapid and high release , while loading by solubilized bFGF and relyophilization led to a low and more regular release of the polypeptide growth factor ." ], "offsets": [ [ 0, 838 ] ] } ]
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{ "id": "MundKieferGesichtschirurgie.0004s474.eng.abstr-s5-t10", "type": "umlsterm", "text": [ "polypeptide" ], "offsets": [ [ 811, 822 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030956" } ] }, { "id": "MundKieferGesichtschirurgie.0004s474.eng.abstr-s5-t11", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 823, 829 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.0004s474.eng.abstr-s5-t12", "type": "umlsterm", "text": [ "In vitro" ], "offsets": [ [ 542, 550 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021135" } ] }, { "id": "MundKieferGesichtschirurgie.0004s474.eng.abstr-s5-t13", "type": "umlsterm", "text": [ "growth factor" ], "offsets": [ [ 823, 836 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018284" } ] } ]
[]
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MundKieferGesichtschirurgie.0004s479.eng.abstr
MundKieferGesichtschirurgie.0004s479.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s479.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : The temporomandibular joint is a place of motion where release of proinflammatory cytokines like interleukin-1 ( IL-1) induces cartilage destruction via production of nitric oxide ( NO ) . The purpose of this study was to evaluate the effects of continuous passive motion in the form of cyclic stretch on the synthesis of inducible nitric oxide synthase ( iNOS ) . Methods : Articular chondrocytes were harvested from rabbit cartilage slices and cultured in F12 medium supplemented with 10% fetal calf serum . Subsequently , cells ( 105/ml per well ) were transferred to Flexercell plates , grown to 90% confluency , and subjected to one of the following regimens : ( 1 ) no mechanical strain ( 10 Hz , 20% elongation rate ) ; ( 2 ) rhIL-1 ( 1 ng/ml ) ; ( 3 ) mechanical strain ; ( 4 ) mechanical strain and rhIL-1. The cells were exposed to cyclic stretch for 24 h . Thereafter , cells were trypsinized and centrifuged on microscope slides in a cytospin centrifuge . The presence of iNOS was determined by indirect immunoperoxidase staining using polyclonal rabbit anti-iNOS as primary antibodies , and goat anti-rabbit IgG conjugated with horseradish peroxidase ( HRP ) as secondary antibodies . Diaminobenzidine was used as substrate for HRP . Total NO production was spectrophotometrically measured in the supernatants of cultures using Greiss reaction . All experiments were done in triplicates and the statistical significance was analyzed by Student's t-test . Results : Cells with treatment 1 and 3 did not exhibit presence of iNOS . IL-1-treated cells in group 2 exhibited intense peroxidase staining . Cells in group 4 exposed to IL-1 and mechanical stress showed staining with considerably less intensity . Control cells treated with normal rabbit IgG as a primary antibody did not exhibit peroxidase staining . The data were further confirmed by measurement of statistically significant differences of NO levels in supernatants assessed in the four different treatment groups . Conclusion : Our findings suggest that continuous passive motion exerts anti-inflammatory effects on chondrocytes , downregulating the quantity of iNOS -positive cells . Since NO acts as an intracellular , transcellular , and cytotoxic molecule , it has a basic importance for proper post-traumatic and postoperative TMJ function as well as the course and therapy of inflammatory TMJ diseases ." ], "offsets": [ [ 0, 2394 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s485.eng.abstr
MundKieferGesichtschirurgie.0004s485.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-passage-0", "type": "abstract", "text": [ "With increasing age of an organism , the osseous regenerative potential is reduced . In osteoblast-like cell cultures , cells of older donors that would not proliferate under standard conditions start to proliferate and express a differentiated phenotype when supplemented with the supernatant of fetal osteoblast-like cultures . The aim of this study was an evaluation of the fetal supernatant actions in vivo . Rat calvaria-derived osteoblasts of fetal and 21-day-old donors were isolated enzymatically and cultured . Their osteoblastic phenotype was confirmed by the expression of typical osteoblast synthesis products . The supernatant of the cultures of each age group was collected and pooled . The supernatant was purified by HPLC and concentrated approximately ten times . Additionally , several age-dependent differences within the purified protein fractions were documented by MALDI . After resuspension , the purified supernatant proteins were transferred on a collagen carrier and implanted into critical size defects of the calvaria of adult Wistar rats . In a control group , the collagen carriers were implanted containing isotonic salt solution . After 2 , 4 , and 8 weeks , a radiographic and histologic analysis of the regeneration process was performed which revealed differences in the progress of mineralization . The methods used in this study might help to identify age-dependent differences regarding the osteoblastic synthesis of osteoanabolic peptides and their impact on the regeneration of osseous defects ." ], "offsets": [ [ 0, 1535 ] ] } ]
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] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 1221, 1229 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s11-t3", "type": "umlsterm", "text": [ "regeneration" ], "offsets": [ [ 1237, 1249 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034963" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 1339, 1346 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "peptides" ], "offsets": [ [ 1469, 1477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030956" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "regeneration" ], "offsets": [ [ 1502, 1514 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034963" } ] }, { "id": "MundKieferGesichtschirurgie.0004s485.eng.abstr-s12-t4", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 1526, 1533 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s490.eng.abstr
MundKieferGesichtschirurgie.0004s490.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s490.eng.abstr-passage-0", "type": "abstract", "text": [ "The utilization of in vitro angiogenesis in tissue engineering might be useful in order to establish an artificial vascular network . However , it remains unclear how far the in vitro preformation of vascular structures may contribute to the perfusion of larger artificial tissue aggregates regarding the improvement of oxygenation and nutrition . In an in vitro study , we developed a model of a vascularized tissue . Stromal cells of a target tissue , e.g. , adipose tissue or bone tissue , were expanded in vitro and seeded onto microcarriers or microparticles . Densely covered microcarriers were brought into a fibrin matrix together with endothelial cells . In order to demonstrate the formation and stabilization of capillary-like structures , UEA-I labeled specimens were evaluated using laser scanning microscopy and digital image analysis . The stabilization of capillary-like structures was better with stromal cells from bone marrow than from adipose tissue . In one of the culture aggregates , the total length of capillary-like structures increased after 6 weeks of cultivation to up to 140 mm/mm3. Additional tests were performed utilizing hyperbaric oxygenation . In the oxygenation group , a significant increase in the length of capillary-like structures was found . The method implies the option of coculturing different tissue elements and of an in vitro preformation of vascularized tissues ." ], "offsets": [ [ 0, 1413 ] ] } ]
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[]
[]
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"normalized": [] } ]
MundKieferGesichtschirurgie.0004s496.eng.abstr
MundKieferGesichtschirurgie.0004s496.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s496.eng.abstr-passage-0", "type": "abstract", "text": [ "This study was performed to demonstrate a protected bone regeneration method using macroporous resorbable sheets for the treatment of extended lower and upper jaw defects . By applying mechanical protection of bony defects with , e.g. membranes or titanium mesh , soft tissue prolapse as well as pressure on bone transplants which contributes to partial resorption can be avoided . The use of a pressure-resistant , resorbable , macroporous sheet combines the advantage of protected bone regeneration and complete resorption of the implanted sheet . The macroporous structure facilitates capillary ingrowth from the surrounding soft tissue . The sheet is made of 70 : 30 Poly ( L-co-DL ) -lactate with thermoplastic character and can be used as a container for autologous spongiosa or other osteoinductive and -conductive bone graft substitutes . In a pilot study , seven patients with lower jaw defects resulting from large cysts or tumor resections , some affecting the continuity of the mandible , were treated with this method . Following a protocol , X-rays were obtained to document the bony regeneration . The positive experience with this pilot study encouraged a multicenter project involving five university hospitals and 50 patients . The application of resorbable sheets in combination with transplantation of mersilized autologous spongiosa is currently being investigated . In future studies , fillings of sheets with osteoconductive and -inductive materials are planned ." ], "offsets": [ [ 0, 1486 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.0004s501.eng.abstr
MundKieferGesichtschirurgie.0004s501.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-passage-0", "type": "abstract", "text": [ "The aim of the following study was to develop an osteoporotic model by means of ovariectomy . Bone mineral density of the upper and lower jaw was measured by dual energy X-ray absorptiometry ( DPX ) before and after ovariectomy . Histomorphometric measurements were done by a microtomography system . Bone mineral density decreased significantly after ovariectomy in the upper and lower jaw ." ], "offsets": [ [ 0, 392 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 4, 7 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "ovariectomy" ], "offsets": [ [ 80, 91 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029936" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Bone" ], "offsets": [ [ 94, 98 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "mineral" ], "offsets": [ [ 99, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026162" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 138, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "X-ray" ], "offsets": [ [ 170, 175 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043299" }, { "db_name": "UMLS", "db_id": "C0043309" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "ovariectomy" ], "offsets": [ [ 216, 227 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029936" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "lower jaw" ], "offsets": [ [ 132, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "Bone mineral density" ], "offsets": [ [ 94, 114 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005938" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "measurements" ], "offsets": [ [ 248, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242485" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Bone" ], "offsets": [ [ 301, 305 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "mineral" ], "offsets": [ [ 306, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026162" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "ovariectomy" ], "offsets": [ [ 352, 363 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029936" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 387, 390 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "lower jaw" ], "offsets": [ [ 381, 390 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.0004s501.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "Bone mineral density" ], "offsets": [ [ 301, 321 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005938" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.0004s504.eng.abstr
MundKieferGesichtschirurgie.0004s504.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-passage-0", "type": "abstract", "text": [ "Computer-assisted prefabricated skull implants of pure titanium as a bone replacement material have been used in 22 departments since 1994. Our experience with 104 implants includes clinical aspects ( indication ; tissue quality ; surgical technique ; patient guidance ) , but also geometric and material-specific parameters ( acquisition , transfer , and evaluation of CT data ; construction ; manufacturing ; cleaning ; postoperative use of radiologic techniques ) . While the clinical aspects are responsibly defined by the respective surgeon , the geometric and material-specific parameters of individual implants have to comply with the laws on medical products . Therefore , the prospective documentation for each implant includes : helical CT acquisition parameters ; geometric data of the computer-based skull model and implant ; the cleaning procedure ; and the individual marking . Medically specified pure titanium is processed by milling only so that neither purity nor structure is impaired . A specially developed milling technique guarantees the fabrication of all constructed elements down to fine details of 50 µm. Considering the necessary radiologic follow-up of defects after tumor surgery , all patients in our hospital undergo postoperative MRI examination , partly with preoperative documentation as an intraindividual control . Such comprehensive documentation and quality assurance is essential for techniques of prefabricated bone substitution . Hand in hand with scientific research and clinical application , these formal criteria have to be elaborated and fulfilled for the respective techniques . The successful determination of specifically adapted MRI sequences goes even one step further : spin-echo sequences minimize inhomogeneities of the magnetic field induced by the titanium implants and enable accurate postoperative documentation and diagnostics especially in the follow-up after tumor surgery ." ], "offsets": [ [ 0, 1936 ] ] } ]
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"MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 240, 249 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 252, 259 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "transfer" ], "offsets": [ [ 341, 349 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040671" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "evaluation" ], "offsets": [ [ 356, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220825" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 422, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 436, 439 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 454, 464 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s1-t13", "type": "umlsterm", "text": [ "bone replacement material" ], "offsets": [ [ 69, 94 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243003" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "implants" ], "offsets": [ [ 609, 617 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013183" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "laws" ], "offsets": [ [ 642, 646 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220866" }, { "db_name": "UMLS", "db_id": "C0023150" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 697, 710 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "computer-based" ], "offsets": [ [ 797, 811 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009622" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "skull" ], "offsets": [ [ 812, 817 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037303" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 851, 860 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "titanium" ], "offsets": [ [ 917, 925 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040302" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "technique" ], "offsets": [ [ 1036, 1045 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "elements" ], "offsets": [ [ 1092, 1100 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013879" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 1182, 1189 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 1196, 1201 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 1202, 1209 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1216, 1224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "hospital" ], "offsets": [ [ 1232, 1240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019994" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 1249, 1262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t9", "type": "umlsterm", "text": [ "MRI" ], "offsets": [ [ 1263, 1266 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024485" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t10", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 1306, 1319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s5-t11", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 1342, 1349 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 1371, 1384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 1424, 1434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 1452, 1456 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "Hand" ], "offsets": [ [ 1472, 1476 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018563" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "hand" ], "offsets": [ [ 1480, 1484 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018563" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "research" ], "offsets": [ [ 1501, 1509 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035168" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "criteria" ], "offsets": [ [ 1550, 1558 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243161" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 1614, 1624 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "determination" ], "offsets": [ [ 1642, 1655 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "MRI" ], "offsets": [ [ 1680, 1683 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024485" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "magnetic" ], "offsets": [ [ 1775, 1783 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024488" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "titanium" ], "offsets": [ [ 1805, 1813 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040302" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 1843, 1856 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t6", "type": "umlsterm", "text": [ "documentation" ], "offsets": [ [ 1857, 1870 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012972" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t7", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 1921, 1926 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t8", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 1927, 1934 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] } ]
[]
[]
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"arg1_id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.0004s504.eng.abstr-s8-t3", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s509.eng.abstr
MundKieferGesichtschirurgie.0004s509.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-passage-0", "type": "abstract", "text": [ "In the quest for bioinert adaptable alloplastic materials , TCP ceramics have gained a new application in craniofacial bone substitutes . Therefore , a histomorphological , intraindividual , comparative study was conducted on seven adult Goettingen miniature pigs ( GMP ) to analyze the difference of the degradation and remodelling processes of -TCP and -TCP in critical size defects of the proximal tibiae . In addition , primary insertion of dental implants followed to study osseous integration . The critical size defects , which were created in the proximal tibiae in GMPs , were filled on the left side with -TCP and on the right side with -TCP . Two GMPs were used as control group . After 4-68 weeks of investigation , the GMPs were sacrificed by narcosis . The histological investigation showed that these ceramics have an osteoconductive effect . It was noted that ossification proceeds centripetally . It could be demonstrated that the degradation of the materials follows a hydrolytical process and that the intratrabecular integrated ceramic remnants follow a dynamic remodelling process . Within 68 weeks after implantation , 90% of the TCP granulae were degraded . Macrophages were found in the marrow space , containing microparticles of TCP , especially after -TCP implantation . In conclusion , defined degradation of these ceramics allows early functional bone regeneration with an additional undisturbed biofunctional unisotrop orientation of new trabeculae . Furthermore , dental implants should be inserted 5-6 months after TCP implantation ." ], "offsets": [ [ 0, 1565 ] ] } ]
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"id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "pigs" ], "offsets": [ [ 259, 263 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039005" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "GMP" ], "offsets": [ [ 266, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0520462" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "degradation" ], "offsets": [ [ 305, 316 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243125" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 377, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "comparative study" ], "offsets": [ [ 191, 208 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009491" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "dental implants" ], "offsets": [ [ 445, 460 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011373" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 519, 526 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 631, 636 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 676, 683 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 676, 689 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "ceramics" ], "offsets": [ [ 816, 824 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007742" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "degradation" ], "offsets": [ [ 948, 959 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243125" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "ceramic" ], "offsets": [ [ 1048, 1055 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007742" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "implantation" ], "offsets": [ [ 1126, 1138 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029976" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "TCP" ], "offsets": [ [ 1152, 1155 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041120" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "Macrophages" ], "offsets": [ [ 1181, 1192 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024432" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "marrow" ], "offsets": [ [ 1211, 1217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376152" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s11-t3", "type": "umlsterm", "text": [ "TCP" ], "offsets": [ [ 1255, 1258 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041120" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s11-t4", "type": "umlsterm", "text": [ "implantation" ], "offsets": [ [ 1283, 1295 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029976" } ] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "degradation" ], "offsets": [ [ 1322, 1333 ] ], 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[]
[]
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}, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-r1-t1.1-t3.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-r2-t2.1-t3.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-r3-t1.1-t2.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t1", "arg2_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-r4-t2.1-t1.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t2", "arg2_id": "MundKieferGesichtschirurgie.0004s509.eng.abstr-s13-t1", "normalized": [] } ]
MundKieferGesichtschirurgie.0004s522.eng.abstr
MundKieferGesichtschirurgie.0004s522.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.0004s522.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduction : The purpose of this study was to investigate the influence of different compositions of resorbable porous glass ceramics on their performance in calvarial defects . Material and Methods : Full-thickness defects ( 8.1 mm diameter ) were made in the calvaria of 75 adult Sprague-Dawley rats . Pellets of porous glass ceramics were inserted press-fit into 60 defects . Four different materials were implanted into each of 15 animals : ( 1 ) glass ceramic with a high relation of calcium to phosphate containing silicate ; ( 2 ) glass ceramic with a high relation of calcium to phosphate without silicate ; ( 3 ) glass ceramic with a low relation of calcium to phosphate without silicate ; and ( 4 ) glass ceramic with a low relation of calcium to phosphate containing silicate . Five implants of each group were evaluated by fluorescence microscopy and light microscopy after 6 , 13 , and 26 weeks . Results : Those glass ceramics with a high relation of calcium to phosphate showed formation of new bone entering the defect from the margins as soon as 6 weeks postoperatively . After 26 weeks , the formation of new bone reached the center of the defect . In the other glass ceramics , the formation of unmineralized osteoid was visible entering the defect from the margins . No mineralization was seen 26 weeks postoperatively . There was no significant difference between glass ceramics containing silicate and those free of silicate . Conclusions : Bioresorbable glass ceramics may be of benefit in the treatment of osseous defects without functional loading ." ], "offsets": [ [ 0, 1576 ] ] } ]
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MundKieferGesichtschirurgie.80020005.eng.abstr
MundKieferGesichtschirurgie.80020005.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-passage-0", "type": "abstract", "text": [ "There is a varying frequency of oral clefts between different ethnic groups and several European regions : however , global investigations on the incidence of oral clefts over longer periods in Germany do not exist , because there has been no continuous system of registering malformations . Such a registration system has been in existence in Magdeburg , with a population of about 1.5 million and a yearly birth rate of about 8000 children , since 1980. A very high rate of oral clefts was found in Magdeburg , mainly a cleft lip with or without a cleft palate , which is a prevalence of 18.5 per 10 000 births . Twenty-two percent of all children with oral clefts had additional malformations . At a rate of about 10% , heart defects were most frequently combined with oral clefts . A significant prevalence increase was recorded in 1988 and 1989. Exogenous influences are being considered as a joint cause for this increase because of the prevalence peaks of neural tube defects from 1987 to 1989." ], "offsets": [ [ 0, 1001 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0243070" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "ethnic groups" ], "offsets": [ [ 62, 75 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015031" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "population" ], "offsets": [ [ 363, 373 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032659" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "birth" ], "offsets": [ [ 408, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005615" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 433, 441 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "lip" ], "offsets": [ [ 528, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153340" }, { "db_name": "UMLS", "db_id": "C0023759" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "palate" ], "offsets": [ [ 556, 562 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700374" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 576, 586 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "births" ], "offsets": [ [ 606, 612 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005615" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "birth rate" ], "offsets": [ [ 408, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005608" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "cleft lip" ], "offsets": [ [ 522, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008924" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "cleft palate" ], "offsets": [ [ 550, 562 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008925" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 641, 649 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "malformations" ], "offsets": [ [ 682, 695 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0243070" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "heart" ], "offsets": [ [ 723, 728 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018787" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 729, 736 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "heart defects" ], "offsets": [ [ 723, 736 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018798" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 800, 810 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "joint" ], "offsets": [ [ 898, 903 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022417" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "cause" ], "offsets": [ [ 904, 909 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 943, 953 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 975, 982 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "MundKieferGesichtschirurgie.80020005.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "neural tube defects" ], "offsets": [ [ 963, 982 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027794" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020011.eng.abstr
MundKieferGesichtschirurgie.80020011.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020011.eng.abstr-passage-0", "type": "abstract", "text": [ "Multimodal therapy of oral squamous cell carcinomas today is based on surgery , radiotherapy and chemotherapy . Despite the combination of all three therapeutic options , there is still a large number of treatment failures and therefore major questions remain . Recent investigations suggest that mutations of the p53 tumor supressor gene may account for some of the therapeutic failures . Inactivation of the gene may be an important determinant of the efficiacy of today's multimodal therapy protocols . In 90 patients with squamous cell carcinomas of the oral cavity biopsy specimens were taken before and after preoperative radiochemotherapy . From all patients , biopsy and resection material was available for immunohistochemical analysis of p53. After radiation treatment , 51 patients ( 57% ) showed a complete response ; 39 patients ( 43% ) only showed a partial response or did not respond at all . Among the responders , 82% of the pretherapeutic tumors were p53 positive , whereas among the nonresponders only 56% of the pretherapeutic tumors were p53 positive . The majority of the residual tumors were also p53 negative according to immunohistology after radiation treatment . In our study , detection of p53 protein by immunohistochemistry seemed to be connected with a more radiosensitive reaction of the tumors . Nevertheless , successful strategies for radiation therapy may need to take into account the tissue of origin and the status of p53 in the tumor ." ], "offsets": [ [ 0, 1476 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020014.eng.abstr
MundKieferGesichtschirurgie.80020014.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020014.eng.abstr-passage-0", "type": "abstract", "text": [ "So-called \" glossitis granulomatosa \" , described in 1952 by H. Schuermann as a peculiar manifestation of Melkersson-Rosenthal syndrome ( MRS ) , is little known in oral medicine due to the paucity of cases published so far . During the past 25 years the author has observed eight definite cases of glossitis granulomatosa and confirmed its close connections with MRS . The recurrent inflammation tends to change into persisting macroglossia with considerable functional and sensory oral disturbances . The clinical diagnosis , histologically supported by biopsy , can definitely be established , yet the outcome of the mostly chronic macroglossitis ( with danger of later tongue carcinoma ) may be very doubtful . Knowledge of Schuermann's glossitis , a member of the group of etiologically unclarified lingual inflammations , is important for physicians involved in oral medicine because of its therapeutic and prognostic implications ." ], "offsets": [ [ 0, 938 ] ] } ]
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"MundKieferGesichtschirurgie.80020014.eng.abstr-s5-t3", "arg2_id": "MundKieferGesichtschirurgie.80020014.eng.abstr-s5-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020014.eng.abstr-s5-r29-t3.1-t5.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020014.eng.abstr-s5-t3", "arg2_id": "MundKieferGesichtschirurgie.80020014.eng.abstr-s5-t5", "normalized": [] } ]
MundKieferGesichtschirurgie.80020020.eng.abstr
MundKieferGesichtschirurgie.80020020.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020020.eng.abstr-passage-0", "type": "abstract", "text": [ "The implantologic rehabilitation of patients after ablative oral tumour surgery and defect reconstruction is carried out generally without strict assessment of the successfulness of the outcome . Therefore 210 dental implants inserted in 58 tumour patients were subjected to regular follow-up examinations for 5 years . The Bone-Lock osseointegrated implant system ( Howmedica Leibinger , Freiburg ) was used exclusively . The plaque index ( Silness and Loee ) , the sulcus bleeding index ( Loee ) , the pocket probing depth , the width of the passive peri-implant tissue , implant mobility by means of the Periotest method and bone resorption according to X-ray findings were ascertained . At 60-70% of measurement points a passive peri-implant tissue was created . After the beginning of loading , specific adaptation phenomena of tumour patients could be detected . Despite constant plaque accumulation ( mean 1.79 ) , the bleeding disposition diminished from maximal 1.83 to 0.71. Corresponding to this finding the pocket probing depths decreased from 5.75 mm to 4.57 mm . The implant mobility ( Periotest method : mean 2.25 , range -3 to +8 . 5 ) showed a decrease in the first 2 years , then the values increased . The mobility depends on the kind of supraconstruction . Ball attachments have the lowest and implant-supported bridges have the highest values . Peri-implant bone resorption showed 1.43 mm as a mean value of all measurements and had a horizontal component of 73-84% . In accordance with this the vertical bone loss was small . After an increase during the first 2 years both values reached a steady state around 2.5 mm . The success rate for all 210 inserted implants is 83.2% . For implants in place for over 365 days the success rate is 93% . Prosthetic restoration in tumour patients can be achieved with osseointegrated dental implants according to the acknowledged international standards ." ], "offsets": [ [ 0, 1916 ] ] } ]
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} ]
[]
[]
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MundKieferGesichtschirurgie.80020026.eng.abstr
MundKieferGesichtschirurgie.80020026.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020026.eng.abstr-passage-0", "type": "abstract", "text": [ "The median palatine suture has long been regarded as having the greatest resistance to dilatation of the maxilla . In 1984 Glassman [ 3 ] presented a conservative-surgical method of division of the palatineal suture in which only the lateral and anterior support of the maxilla is debilitated surgically . An orthodontic apparatus cemented in place preoperatively is already used intraoperatively for dilatation of the maxilla . In the period from 1991 to 1997 , 16 patients with a leptomaxilla and various dysnathic findings have been operated on at our clinic by the method described by Glassman [ 3 ] . Sometimes the maxilla was dilated intraoperatively using the apparatus cemented in place by the method of Derichsweiler and dilatation was continued postoperatively until the described result was achieved . After successful dilatation of the maxilla and a stabilizing phase , a mono- or bimaxillary operation was performed . The use of this method led to the desired result in 15 patients . Dilatation of the maxilla was objectivized by determining the pre- and postoperative width of the anterior and posterior dental arch using models and X-ray of the occlusal overlay of the maxilla . In one patient who was operated on at the age of 38 years , a fracture of the alveolar process of the maxilla occurred unilaterally due to the completed ossification of the median palatine suture . The method of surgically aided dilatation of the maxilla at the level of Le Fort I plane is suitable for patients up to the age of 30. In older patients , the median palatine suture should be transsected as well ." ], "offsets": [ [ 0, 1605 ] ] } ]
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MundKieferGesichtschirurgie.80020030.eng.abstr
MundKieferGesichtschirurgie.80020030.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-passage-0", "type": "abstract", "text": [ "Mutations of the p53 gene are the most commonly observed genetic alterations in malignant tumors and are often associated with a loss of the tumor suppressor function of the p53 protein . We have analyzed specimens of head and neck squamous cell carcinomas ( HNSCC ) from 110 patients for p53 gene mutations and 92 of them additionally for human papillomavirus ( HPV ) infection in order to evaluate the prognostic significance of these factors by comparison with clinical follow-up data . Using the method of polymerase chain reaction ( PCR ) / temperature gradient gel electrophoresis ( TGGE ) , mutations within the exons 5 to 8 of the p53 gene were found in 48 tumors ( 44% ) . Sequencing revealed missense mutations in most cases ( 15/20 ) . Frequency of p53 gene mutations was not related to the tumor stage , the grade of differentiation , the presence of lymph node metastases , or the smoking history of the patients . With the help of a highly sensitive PCR/hybridization assay , an infection with the high-risk HPV types 16 and 18 could be detected in 39/92 tumor specimens ( 42% ) . Follow-up data were obtained from 99 patients with a range of 2- 112 months . No correlation of overall survival on the presence of p53 gene mutations or HPV infection could be observed . The absence of statistically significant correlations between p53 gene mutations and progressive disease , however , does not exclude its putative relevance in early phases of tumor development ." ], "offsets": [ [ 0, 1478 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Mutations" ], "offsets": [ [ 0, 9 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 21, 25 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "malignant" ], "offsets": [ [ 80, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 90, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 141, 146 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "function" ], "offsets": [ [ 158, 166 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031843" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "protein" ], "offsets": [ [ 178, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 17, 25 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "genetic alterations" ], "offsets": [ [ 57, 76 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017384" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "malignant tumors" ], "offsets": [ [ 80, 96 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "tumor suppressor" ], "offsets": [ [ 141, 157 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079427" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "p53 protein" ], "offsets": [ [ 174, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080055" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 218, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 227, 231 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 241, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 246, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 276, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 293, 297 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 298, 307 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 340, 345 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "papillomavirus" ], "offsets": [ [ 346, 360 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030358" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "HPV" ], "offsets": [ [ 363, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021344" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 369, 378 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t12", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 289, 297 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s2-t13", "type": "umlsterm", "text": [ "human papillomavirus" ], "offsets": [ [ 340, 360 ] ], "normalized": 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"MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "gel" ], "offsets": [ [ 567, 570 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017243" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "electrophoresis" ], "offsets": [ [ 571, 586 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013855" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 598, 607 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "exons" ], "offsets": [ [ 619, 624 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015295" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 643, 647 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 665, 671 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t10", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 639, 647 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s3-t11", "type": "umlsterm", "text": [ "polymerase chain reaction" ], "offsets": [ [ 510, 535 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032520" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 711, 720 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "missense mutations" ], "offsets": [ [ 702, 720 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0599155" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Frequency" ], "offsets": [ [ 747, 756 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 764, 768 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 769, 778 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 802, 807 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "stage" ], "offsets": [ [ 808, 813 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 863, 868 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "metastases" ], "offsets": [ [ 874, 884 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "smoking" ], "offsets": [ [ 894, 901 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037369" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t9", "type": "umlsterm", "text": [ "history" ], "offsets": [ [ 902, 909 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019664" }, { "db_name": "UMLS", "db_id": "C0019665" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t10", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 917, 925 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t11", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 760, 768 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s5-t12", "type": "umlsterm", "text": [ "lymph node" ], "offsets": [ [ 863, 873 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "assay" ], "offsets": [ [ 982, 987 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243073" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 993, 1002 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "HPV" ], "offsets": [ [ 1022, 1025 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021344" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 1069, 1074 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1132, 1140 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "overall" ], "offsets": [ [ 1191, 1198 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282416" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "survival" ], "offsets": [ [ 1199, 1207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220921" }, { "db_name": "UMLS", "db_id": "C0038952" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 1231, 1235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 1236, 1245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "HPV" ], "offsets": [ [ 1249, 1252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021344" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t6", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 1253, 1262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s8-t7", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 1227, 1235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 1349, 1353 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "mutations" ], "offsets": [ [ 1354, 1363 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026882" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t3", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 1380, 1387 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 1459, 1464 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t5", "type": "umlsterm", "text": [ "development" ], "offsets": [ [ 1465, 1476 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243107" }, { "db_name": "UMLS", "db_id": "C0020119" } ] }, { "id": "MundKieferGesichtschirurgie.80020030.eng.abstr-s9-t6", "type": "umlsterm", "text": [ "p53 gene" ], "offsets": [ [ 1345, 1353 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079419" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020035.eng.abstr
MundKieferGesichtschirurgie.80020035.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-passage-0", "type": "abstract", "text": [ "A rare case of well-differentiated syringomatous carcinoma of the nose , at first histologically misdiagnosed as morpheiform basal cell carcinoma , presented as an ulcerated nasal mass . Recurrence of the the tumor and repeated histological examination of tissue specimens led to revision of the primary diagnosis . The histological features of the two entities are compared . The clinician should be aware that knowledge of the biological behavior of this tumor is sparse ( based on less than 100 cases ) and that the tumor possesses some features of malignancy , requiring a very careful and close follow-up ." ], "offsets": [ [ 0, 611 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "syringomatous" ], "offsets": [ [ 35, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206673" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 49, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "nose" ], "offsets": [ [ 66, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028429" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 131, 135 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 136, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "basal cell carcinoma" ], "offsets": [ [ 125, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007117" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Recurrence" ], "offsets": [ [ 187, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034897" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 209, 214 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 256, 262 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 304, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 412, 421 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "behavior" ], "offsets": [ [ 440, 448 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004927" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 457, 462 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 519, 524 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020035.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "malignancy" ], "offsets": [ [ 552, 562 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020042.eng.abstr
MundKieferGesichtschirurgie.80020042.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-passage-0", "type": "abstract", "text": [ "Leiomyosarcomas in the mandible are extremely rare . The cases of a 40-year-old woman with a leiomyosarcoma in the mandible is reported . Diagnostic and therapeutic problems are discussed ." ], "offsets": [ [ 0, 189 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Leiomyosarcomas" ], "offsets": [ [ 0, 15 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023269" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 23, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "woman" ], "offsets": [ [ 80, 85 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "leiomyosarcoma" ], "offsets": [ [ 93, 107 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023269" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 115, 123 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Diagnostic" ], "offsets": [ [ 138, 148 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020042.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 153, 164 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] } ]
[]
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MundKieferGesichtschirurgie.80020044.eng.abstr
MundKieferGesichtschirurgie.80020044.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-passage-0", "type": "abstract", "text": [ "Odontogenic fibromyxomas are extremely rare , benign odontogenic tumours , found preferentially in the second and third decades of life . They have a preference for the mandible . The present case report describes a 25-year-old patient with an odontogenic fibromyxoma in the lower jaw . Differential diagnosis , histology and therapy of this neoplasm are described ." ], "offsets": [ [ 0, 366 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "fibromyxomas" ], "offsets": [ [ 12, 24 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205766" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "tumours" ], "offsets": [ [ 65, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "life" ], "offsets": [ [ 131, 135 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376558" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "odontogenic tumours" ], "offsets": [ [ 53, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028880" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 169, 177 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 228, 235 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "fibromyxoma" ], "offsets": [ [ 256, 267 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205766" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 281, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "case report" ], "offsets": [ [ 192, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007320" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "lower jaw" ], "offsets": [ [ 275, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 300, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "histology" ], "offsets": [ [ 312, 321 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019638" }, { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 326, 333 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "neoplasm" ], "offsets": [ [ 342, 350 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" }, { "db_name": "UMLS", "db_id": "C0036210" } ] }, { "id": "MundKieferGesichtschirurgie.80020044.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "Differential diagnosis" ], "offsets": [ [ 287, 309 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220820" }, { "db_name": "UMLS", "db_id": "C0011906" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020058.eng.abstr
MundKieferGesichtschirurgie.80020058.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020058.eng.abstr-passage-0", "type": "abstract", "text": [ "Squamous cell cancer of the oral cavity mainly occurs in older patients or in patients with alcohol or nicotine abuse . Younger patients are seldom involved . The case of a 27-year-old woman with a squamous cell cancer of the right cheek will be presented . Without any risk factors , an immune defect resulting in chronic Candida infection of the oral cavity seems to be responsible for the carcinogenesis ." ], "offsets": [ [ 0, 408 ] ] } ]
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[]
[]
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"arg2_id": "MundKieferGesichtschirurgie.80020058.eng.abstr-s4-t4", "normalized": [] } ]
MundKieferGesichtschirurgie.80020062.eng.abstr
MundKieferGesichtschirurgie.80020062.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020062.eng.abstr-passage-0", "type": "abstract", "text": [ "Diagnostic pitfalls exist when benign salivary gland diseases are mistakenly classified as malignant , with consequences for treatment and prognosis . Examples are necrotizing sialometaplasia , metaplastic Warthin tumour and sclerosing polycystic sialadenopathy . The proper diagnosis is of eminent importance to distinguish cases of primary tumours that have developed in salivary glands or their lymph nodes from cases of extraglandular tumours with metastases in these glands or their nodes . In these cases clinical data and additional immunocytochemical methods are necessary to clarify the exact diagnosis , especially when the primary salivary gland tumours have a structure largely identical to the metastases ( e.g. squamous cell carcinoma ) . Nasopharyngeal or cervical chordomas can be mistaken for pleomorphic adenoma or mucinous adenocarcinoma . The initial stage of malignant MALT lymphomas in association with Sjoegren's syndrome demands identification of clonal rearrangement for therapeutic implication . The diagnostic criteria for proper classification are analysed in detail ." ], "offsets": [ [ 0, 1096 ] ] } ]
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[]
[]
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"MundKieferGesichtschirurgie.80020062.eng.abstr-s6-r42-t8.1-t9.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020062.eng.abstr-s6-t8", "arg2_id": "MundKieferGesichtschirurgie.80020062.eng.abstr-s6-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020062.eng.abstr-s6-r43-t1.1-t2.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020062.eng.abstr-s7-t1", "arg2_id": "MundKieferGesichtschirurgie.80020062.eng.abstr-s7-t2", "normalized": [] } ]
MundKieferGesichtschirurgie.80020070.eng.abstr
MundKieferGesichtschirurgie.80020070.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-passage-0", "type": "abstract", "text": [ "The crucial factor deciding the success of cardiopulmonary resuscitation is a sufficient oxygen supply . At about 4 min after cardiac arrest , cerebral death results because of hypoxia , and cardiopulmonary resuscitation has to be started regardless of the pathogenesis of the cardiac arrest . The purpose of the study was to assess the application of guidelines for cardiopulmonary resuscitation by participants at a dental surgery congress ( n = 96 ) and to evaluate previous knowledge in cardiopulmonary resuscitation and knowledge after instruction . The present study was based on the standards and guidelines for cardiopulmonary resuscitation issued by the American Heart Association . The group was divided into four groups of doctors experienced or inexperienced in clinical emergencies or with dummies . For the study the Skillmeter-Resusci-Anne ( Laerdal , Stavanger , Norway ) was used , which has automatic data recording . After analysis of the individual errors , the success of new instruction was assessed . Good previous knowledge was registered , particularly with respect to checking respiration and hyperextension of the head ( 67.7% ) , primary insufflation ( 93.8% ) , closed-chest cardiac massage ( 99% ) and correct compression rate ( 68.4% ) . The participants demonstrated post-instruction improvement in all subdivisions except in the group without practice on dummies ( primary insufflation : from 94.4 to 88.9% ; correct order of checking consciousness and respiration , primary insufflation , the carotid pulse and closed-chest cardiac massage : from 22.2 to 5.6% ) . Good results with marked improvements in the second passage were achieved in checking consciousness and the carotid pulse , closed-chest cardiac massage and correct implementation of compression . The participants were , however , found to be in need of further education and training in diagnostics and certain cardiopulmonary resuscitation measures . Knowledge should be improved concerning recognition of the emergency ( 42.7% ) , checking the carotid pulse ( 22.9% ) , the correct order of primary insufflation and closed-chest cardiac massage ( 9.4% ) , correct implementation of compression ( 21.8% ) and ventilation ( 36.4% ) , and the correct ratio of compression and ventilation ( 21.9% ) . Regular courses should be targeted at these specific aspects ." ], "offsets": [ [ 0, 2360 ] ] } ]
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[ "death" ], "offsets": [ [ 152, 157 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011065" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "hypoxia" ], "offsets": [ [ 177, 184 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242184" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "resuscitation" ], "offsets": [ [ 207, 220 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035273" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "pathogenesis" ], "offsets": [ [ 257, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543483" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "cardiac arrest" ], "offsets": [ [ 126, 140 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018790" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "cerebral death" ], "offsets": [ [ 143, 157 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006110" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "cardiopulmonary resuscitation" ], "offsets": [ [ 191, 220 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007203" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "cardiac arrest" ], "offsets": [ [ 277, 291 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018790" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "guidelines" ], "offsets": [ [ 352, 362 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220845" }, { "db_name": "UMLS", "db_id": "C0162791" }, { "db_name": "UMLS", "db_id": "C0282423" } ] }, { "id": "MundKieferGesichtschirurgie.80020070.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "resuscitation" ], "offsets": [ [ 383, 396 ] ], 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[]
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MundKieferGesichtschirurgie.80020078.eng.abstr
MundKieferGesichtschirurgie.80020078.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-passage-0", "type": "abstract", "text": [ "Purpose : Alcohol and nicotine abuse play a major role in the etiology of oral squamous cell carcinomas . In the present study , we investigated the number of patients with oral/oropharyngeal carcinomas who regularly consume alcohol and nicotine and what type of specific treatment should be prescribed for the addiction . Patients and Method : A total of 105 patients ( 90 men , 15 women ) with oral/oropharyngeal squamous cell carcinomas were studied based on catamnestic data as well as a special questionnaire designed to assess drinking and smoking habits ( 40 g alcohol/day for men and 20 g alcohol/day for women was taken as the standard measure for those considered at risk for alcoholism ) . For smokers , the number of packs smoked per year was determined and compared to clinical data ( i.e. , tumor size , location ) and laboratory data ( -GT ) . Particular attention was given to the addiction behavior before and after tumor therapy ( recorded at least 1 year after successful tumor treatment ) . Results : At the time of diagnosis , 83.1% regularly drank alcohol ( 71.9% reported drinking over 40 g/ 20 g of alcohol per day ) . Another 17.9% stopped drinking after therapy . Of the alcoholics 59.8% had been exposed to a daily consumption level above the threshold amount for more than 20 years . Some 70% of the patients reported that they exclusively drank beer . Tobacco consumption came from cigarette smoking 92.7% and 89.7% reported that they smoked before therapy - after therapy only 37.8% smoked . Carcinomas of the floor of the mouth indicated a prevalence toward alcohol and nicotine abuse . Of the patients with a T3 and T4 carcinoma 84% had daily alcohol consumption levels over the threshold value stated above . None of the 105 patients underwent specific alcohol treatment therapy . Conclusion : In light of the high prevalence of carcinomas of the oral cavity in patients with alcohol and nicotine addiction , mandatory withdrawal therapy should be offered in the form of postoperative treatment to prevent recurrence or the development of second primary tumors , as well as to improve the quality of life and encourage social rehabilitation . Before further treatment , for example , with retinoids , a successful withdrawal treatment should be completed ." ], "offsets": [ [ 0, 2289 ] ] } ]
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"UMLS", "db_id": "C0007463" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 88, 92 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 93, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "squamous cell carcinomas" ], "offsets": [ [ 79, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 159, 167 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 192, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "alcohol" ], "offsets": [ [ 225, 232 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001975" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "nicotine" ], "offsets": [ [ 237, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028040" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 272, 281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 323, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020078.eng.abstr-s3-t2", "type": "umlsterm", 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[]
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MundKieferGesichtschirurgie.80020085.eng.abstr
MundKieferGesichtschirurgie.80020085.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-passage-0", "type": "abstract", "text": [ "Objective : The volume of literature on radiation-induced caries is still inconsistent as regards the state of the art . Our histotomographic studies have shown direct radiogenic effects on the dentoenamel junction ( atrophy of the odontoblast processes ) . Whether there are direct effects of radiation on dental enamel is not yet known . Material and Method : Sound teeth ( group 1 , n = 10 ) were compared either with enamel specimens after high dose in vitro radiation ( 500- 2500 Gy ; group 2 ; n = 10 ) and after experimental enoral in situ irradiation ( 60 Gy ; group 3 ; n = 20 ) , or with teeth from patients after cancer radiotherapy ( 36 Gy ; group 4 ; n = 20 ) and with teeth which had obviously decayed due to cancer radiotherapy ( 60 Gy ; group 5 ; n = 20 ) . Vestibular enamel surfaces of the teeth were exposed to identical in vitro demineralizations ( lactic acid gel ; pH = 5.0 ) . Each of the samples was prospectively studied histologically by confocal laser scanning microscopy ( CLSM ) after 90 , 180 and 270 min of acid interaction . Data were interpreted micromorphometrically ( width of the demineralized area ) and micromorphologically . Results : The width of the demineralized area varies between the two in vivo irradiated groups of specimens ( group 4 : P 0.01 ; group 5 : P 0.001 ) and the high dose in vitro irradiated teeth ( P 0.01 ) and is significantly different from the sound controls . The histological image of the demineralization in subsurface areas in the teeth of radiotherapy patients is characterized by a total loss of the prismatic structure ( homogeneously , amorphous substance ) . Conclusions : Direct radiogenic effects at the dentoenamel junction have been described earlier . The additional information offered by this study is that there are significant micromorphometric differences in the demineralizing behaviour of irradiated enamel . Obviously , enamel is less resistant to acid attack after irradiation ." ], "offsets": [ [ 0, 1965 ] ] } ]
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] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "atrophy" ], "offsets": [ [ 217, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004255" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "odontoblast" ], "offsets": [ [ 232, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028875" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "direct" ], "offsets": [ [ 276, 282 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700157" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "radiation" ], "offsets": [ [ 294, 303 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0851346" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "enamel" ], "offsets": [ [ 314, 320 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011350" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "dental enamel" ], "offsets": [ [ 307, 320 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011350" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "effects of radiation" ], "offsets": [ [ 283, 303 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034525" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Method" ], "offsets": [ [ 353, 359 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "Sound" ], "offsets": [ [ 362, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037709" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "teeth" ], "offsets": [ [ 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"db_id": "C0021135" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "lactic acid" ], "offsets": [ [ 869, 880 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0064582" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 973, 978 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "microscopy" ], "offsets": [ [ 988, 998 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026018" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "acid" ], "offsets": [ [ 1038, 1042 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "MundKieferGesichtschirurgie.80020085.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "interaction" ], "offsets": [ [ 1043, 1054 ] ], "normalized": [ { 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[]
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MundKieferGesichtschirurgie.80020091.eng.abstr
MundKieferGesichtschirurgie.80020091.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020091.eng.abstr-passage-0", "type": "abstract", "text": [ "Anatomic , life-like , three-dimensional models have a definite place in cranio-maxillofacial surgery . Our experience with 541 computer tomographic ( CT ) -based three-dimensional ( 3D ) -models for diagnostic purposes , preoperative planning and model operations in our department was gained using stereolithographic and milled models . The question of which production method is preferable is a matter of controversy in the literature . Both methods are based on CT and magnetic resonance imaging data , but the differences in production give rise to specific advantages and disadvantages . For comparison we scanned two measurement models , fabricated milled and stereolithographic models , and analyzed the differences concerning accuracy and shape of specific structures . The scan distance ( feed ) is the limiting factor for the accuracy for both methods . Milled models show the highest precision in the plane of CT scanning - the more oblique the measurements became to this plane , the greater the decrease in accuracy . Hollows and undercuts can only be produced by splitting the model . Stereolithographic models show higher deviations with randomly distributed errors . The mean deviation was 0.81 mm on stereolithography and 0.54 mm on milled models . The accuracy of both methods is sufficient for clinical use . In routine cases the milling method seems to be superior because of shorter production time and lower costs . In special cases , where hollows and fine structures play a major role , stereolithography is the method of choice ." ], "offsets": [ [ 0, 1555 ] ] } ]
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"MundKieferGesichtschirurgie.80020091.eng.abstr-s13-t1", "arg2_id": "MundKieferGesichtschirurgie.80020091.eng.abstr-s13-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020091.eng.abstr-s13-r6-t2.2-t1.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020091.eng.abstr-s13-t2", "arg2_id": "MundKieferGesichtschirurgie.80020091.eng.abstr-s13-t1", "normalized": [] } ]
MundKieferGesichtschirurgie.80020101.eng.abstr
MundKieferGesichtschirurgie.80020101.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020101.eng.abstr-passage-0", "type": "abstract", "text": [ "An unusual case of nonhealing necrotizing gingivostomatitis in a 66-year-old man is described . Microscopic examination of biopsy material showed an infiltrate of Langerhans cells . Merely oral lesions of Langerhans cell granulomatosis - especially in an old person - occur very seldom ." ], "offsets": [ [ 0, 287 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020118.eng.abstr
MundKieferGesichtschirurgie.80020118.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020118.eng.abstr-passage-0", "type": "abstract", "text": [ "Aim : To investigate the distribution of Laminin in experimental microvascular surgery . Material and methods : Autografts ( 4 mm ) of the left common carotid artery in 20 Wistar rats were harvested after 4 weeks . The specimens were investigated immunohistochemically for the demonstration and distribution of Laminin . Results : The demonstration and distribution pattern of Laminin was a function of the accuracy of each single suture . In the intima , the organisation and amount of Laminin was directed to the lumen and dependent from the distance and vitality of the vessel segments ' cells . The media had in its axis direction the lowest reparative potency to regenerate the continuity break . The adventitia formed a thick cuff around the anastomosis , which was circularly grown through with Laminin-positive vasa vasorum . The marked myointimal hyperplasia in the area around the anastomosis and in the entire autograft was constituted of Laminin-positive extracellular matrix . Conclusions : Our results support the demand for a careful and atraumatic suture technique in microvascular surgery ." ], "offsets": [ [ 0, 1107 ] ] } ]
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[]
[]
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"MundKieferGesichtschirurgie.80020118.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s8-r7-t1.1-t3.1", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t1", "arg2_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s8-r8-t1.1-t2.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t1", "arg2_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-r1-t2.2-t1.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t2", "arg2_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-r2-t2.2-t1.1", "type": "method_of", "arg1_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t2", "arg2_id": "MundKieferGesichtschirurgie.80020118.eng.abstr-s9-t1", "normalized": [] } ]
MundKieferGesichtschirurgie.80020122.eng.abstr
MundKieferGesichtschirurgie.80020122.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020122.eng.abstr-passage-0", "type": "abstract", "text": [ "In this publication , Nager syndrome was analyzed in the literature and six patients from our clinic were evaluated in relation to symptoms , etiology and pathogenesis . The diseases to be considered when making a differential diagnostis are pointed out . Clarification of the etiology is still pending . Molecular genetic research in these patients is possibly the key for new findings . A case report illustrates the results of interdisciplinary treatment by the surgeon and orthodontist . Possibilities and problems in relation to therapy are demonstrated ." ], "offsets": [ [ 0, 560 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020131.eng.abstr
MundKieferGesichtschirurgie.80020131.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020131.eng.abstr-passage-0", "type": "abstract", "text": [ "One of the most severe early side effects of radiation in head and neck cancer patients is mucositis . Inflammation of the oral mucose may lead to an extreme subjective burden , restricting the patients ' well-being and even leading to an interruption of radiotherapy . The aim of our prospective study was to investigate the pathological alterations of the oral mucosa during irradiation . Therefore , samples from head and neck cancer patients were taken before radiation and a 30-G and a 60-G radiation dose . Pathogenetic alterations were determined by immunohistochemical staining of various cell surface molecules known to be involved in the pathogenesis of inflammation . Staining was performed with antibodies against ICAM 1 , VCAM 1 , ELAM , 25F9, 27E10, and RM3-1. Our study demonstrates the expression rates of the various surface molecules during inflammation . Expression of RM3-1 and ICAM 1 showed a steep increase during the time of radiation , whereas expression of ELAM reached a low constant value . Therefore , we conclude that distinct cell surface molecules demonstrate a characteristic time-dependent expression during radiation . Better insight into the pathogenesis of radiation-induced mucositis may help to develop a pathological classification of mucositis and to improve therapeutic strategies ." ], "offsets": [ [ 0, 1323 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020136.eng.abstr
MundKieferGesichtschirurgie.80020136.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-passage-0", "type": "abstract", "text": [ "The standard drill size for most osteosynthesis screws is about 75% of the screw's external diameter . When screws are inserted in thick cortical bone , a small pilot hole size can result in high torsional stress , leading to screw fracturing . The aim of this study was to enlarge the drill size up to a critical pilot hole size , exceeding of which leads to a rapid decrease of the screw's holding power . Titanium screws of diameter 1.5 and 2 mm were inserted in discs of PVC , wood and porcine mandibular bone with different thickness between 2 to 4 mm , using pilot hole sizes of 66- 95% of the screw's external diameter . The maximum torque was recorded and pull-out tests were performed . Ten trials were conducted for each screw-pilot hole size-material combination , yielding a total of 1560 tests . A multiphase regression analysis was performed to calculate the critical pilot hole size ( CPHS ) . In torque measurements , the CPHS of microscrews were between 83% and 85% of screw outer diameter ( SOD ) and the CPHS of miniscrews were between 80% and 90% of SOD . In pull-out analysis the CPHS of microscrews were between 83% and 89% of SOD and the CPHS of miniscrews were between 79% and 91% of SOD . The CPHS was thus found to be around 85% of the screw's external diameter . Up to this critical point the pilot hole size may be increased without affecting the holding power of the screws ." ], "offsets": [ [ 0, 1404 ] ] } ]
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"UMLS", "db_id": "C0005975" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 146, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "stress" ], "offsets": [ [ 206, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038435" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 249, 252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "drill" ], "offsets": [ [ 286, 291 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0324815" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "screw's" ], "offsets": [ [ 384, 391 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0605770" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "power" ], "offsets": [ [ 400, 405 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032863" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Titanium" ], "offsets": [ [ 408, 416 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040302" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 417, 423 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "PVC" ], "offsets": [ [ 475, 478 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0151636" }, { "db_name": "UMLS", "db_id": "C0032624" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "wood" ], "offsets": [ [ 481, 485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043217" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "porcine" ], "offsets": [ [ 490, 497 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039005" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 509, 513 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "screw's" ], "offsets": [ [ 600, 607 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0605770" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "torque" ], "offsets": [ [ 640, 646 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376590" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "tests" ], "offsets": [ [ 673, 678 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "tests" ], "offsets": [ [ 801, 806 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "regression" ], "offsets": [ [ 822, 832 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034979" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 833, 841 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "regression analysis" ], "offsets": [ [ 822, 841 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034980" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "torque" ], "offsets": [ [ 912, 918 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376590" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "measurements" ], "offsets": [ [ 919, 931 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242485" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "screw" ], "offsets": [ [ 986, 991 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "SOD" ], "offsets": [ [ 1009, 1012 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038838" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "SOD" ], "offsets": [ [ 1070, 1073 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038838" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 1088, 1096 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "SOD" ], "offsets": [ [ 1149, 1152 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038838" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "type": "umlsterm", "text": [ "SOD" ], "offsets": [ [ 1208, 1211 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038838" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "screw's" ], "offsets": [ [ 1262, 1269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0605770" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "power" ], "offsets": [ [ 1383, 1388 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032863" } ] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "screws" ], "offsets": [ [ 1396, 1402 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005975" } ] } ]
[]
[]
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}, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r2-t1.1-t7.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r3-t6.1-t3.2", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t6", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r4-t7.1-t3.2", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r5-t1.1-t3.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r6-t1.1-t3.2", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r7-t6.1-t7.1", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t6", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r8-t3.2-t3.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r9-t4.1-t3.1", "type": "causes", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r10-t6.1-t5.1", "type": "part_of", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t6", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r11-t3.2-t1.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r12-t7.1-t1.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r13-t6.1-t3.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t6", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r14-t3.1-t5.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r15-t7.1-t3.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r16-t7.1-t4.1", "type": "isa", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r17-t3.2-t4.1", "type": "isa", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r18-t2.1-t3.1", "type": "treats", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-r19-t3.2-t7.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s4-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-r1-t2.1-t1.1", "type": "measurement_of", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-r2-t2.1-t1.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s7-r3-t2.1-t1.1", "type": "assesses_effect_of", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-r1-t4.1-t5.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-r2-t2.1-t4.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-r3-t5.1-t4.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-r4-t2.1-t5.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s8-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-r1-t3.1-t1.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-r2-t1.1-t3.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-r3-t1.1-t3.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-r4-t1.1-t3.1", "type": "analyzes", "arg1_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020136.eng.abstr-s9-t3", "normalized": [] } ]
MundKieferGesichtschirurgie.80020141.eng.abstr
MundKieferGesichtschirurgie.80020141.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-passage-0", "type": "abstract", "text": [ "Objectives : Fixation ( formalin ) , decalcification ( sections ) or mechanical treatment ( grinding ) all bear the risk of artifacts occurring during hard-tissue histology . Because studies on the etiology of pathological changes mostly focus on subclinical lesions , artifacts can simulate early changes or even be superimposed on existing changes . The objective of this study was to determine how artifacts can be reduced . Material and methods : In confocal laser scanning microscopy ( CLSM ) a focused laser beam scans the surface of the specimens and penetrates into the tissue . The intensity of the remitted light is recorded . The confocal effect is due to an extremely small aperture ( pinhole ) , excluding light from out-of-focus planes of the sample . By stepwise movement of the object table , a tomographic series of tomographic images is obtained . Sound cortical bone samples of the lower jaw ( n = 20 ) were studied by light microscopy and by CLSM , visualizing identical areas of a ground sectioned sample after H & E staining . Additionally , embedded and fresh blocks of tissue of the same bone sample were studied histotomographically in the CLSM . Results : ( 1 ) Light microscopic micromorphology of cortical bone can be visualized adequately in the CLSM ; ( 2 ) many structures that can be visualized by light microscopy only after special staining ( e.g. , osteozyte processes ) can be visualized by the CLSM using sample blocks without pretreatment . Conclusion : ( 1 ) Nondestructive subsurface histotomography by CLSM totally excludes mechanical artifacts ; ( 2 ) physicochemical artifacts can be handled more easily because fresh samples can be studied ; ( 3 ) pseudo-three-dimensional imaging allows histological interpretation of the tissue that is equivalent to macroscopic tomographic techniques ( CT , MRT ) ." ], "offsets": [ [ 0, 1845 ] ] } ]
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"db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "artifacts" ], "offsets": [ [ 124, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085089" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "hard-tissue" ], "offsets": [ [ 151, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018599" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "hard-tissue" ], "offsets": [ [ 151, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "histology" ], "offsets": [ [ 163, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019638" }, { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "risk of" ], "offsets": [ [ 116, 123 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "etiology" ], "offsets": [ [ 198, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" }, { "db_name": "UMLS", "db_id": "C0007463" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "artifacts" ], "offsets": [ [ 269, 278 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085089" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "objective" ], "offsets": [ [ 356, 365 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018017" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "artifacts" ], "offsets": [ [ 401, 410 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085089" } ] }, { "id": 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"UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "laser scanning microscopy" ], "offsets": [ [ 463, 488 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600396" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 617, 622 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 719, 724 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "movement" ], "offsets": [ [ 778, 786 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026649" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "Sound" ], "offsets": [ [ 866, 871 ] ], "normalized": [ 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"db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 1093, 1099 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 1112, 1116 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "Light" ], "offsets": [ [ 1188, 1193 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "micromorphology" ], "offsets": [ [ 1206, 1221 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543482" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s10-t3", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 1234, 1238 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s10-t4", "type": "umlsterm", "text": [ "light" ], "offsets": [ [ 1330, 1335 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023693" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s10-t5", "type": "umlsterm", "text": [ "microscopy" ], "offsets": [ [ 1336, 1346 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026018" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "artifacts" ], "offsets": [ [ 1576, 1585 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085089" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "artifacts" ], "offsets": [ [ 1610, 1619 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085089" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "type": "umlsterm", "text": [ "imaging" ], "offsets": [ [ 1717, 1724 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t4", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 1767, 1773 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t5", "type": "umlsterm", "text": [ "techniques" ], "offsets": [ [ 1820, 1830 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025664" } ] } ]
[]
[]
[ { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r1-t8.1-t2.1", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r2-t9.2-t3.1", "type": "evaluation_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r3-t9.2-t3.1", "type": "conceptual_part_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r4-t5.1-t9.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t5", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r5-t8.1-t3.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r6-t6.1-t9.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r7-t7.1-t3.1", "type": "evaluation_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t7", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r8-t8.1-t3.1", "type": "part_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r9-t7.1-t9.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t7", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r10-t8.1-t9.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r11-t2.1-t8.1", "type": "disrupts", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t8", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r12-t1.1-t9.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t1", "arg2_id": 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"arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-t9", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s1-r18-t5.1-t3.1", "type": "conceptual_part_of", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t5", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s4-r1-t3.1-t1.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t3", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s4-r2-t6.1-t1.1", "type": "measures", "arg1_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020141.eng.abstr-s8-r1-t5.1-t1.1", "type": "assesses_effect_of", "arg1_id": 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MundKieferGesichtschirurgie.80020146.eng.abstr
MundKieferGesichtschirurgie.80020146.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-passage-0", "type": "abstract", "text": [ "Children with craniofacial malformations are at special risk for the development of peripheral airway obstruction . The problems are magnified in patients with retroposition or hypoplasia of the mandible . In these cases , the base of the tongue is posteriorly displaced , hereby decreasing the airway diameter . By application of distraction osteogenesis the mandible can be lengthened to move the base of the tongue forward and open the airway . Three female patients aged between 7 , 11 , and 15 months suffering from peripheral airway obstruction caused by mandibular hypoplasia were treated by gradual distraction . All of them had a gastrostomy or a nasogastral tube in place , respectively , due to severe nutrition problems . In the youngest patient tracheostomy was performed shortly after birth and was already planned in the 15-month-old child , who had received a permanent nasopharyngeal tube . The 11-month-old child suffered from severe refractory sleep apnea . Exercises in oral feeding were possible in the youngest patient after 10 days of distraction . In the oldest one , the airway tube was removed on the six day of distraction and , thus , tracheotomy was successfully avoided . In the 11-month-old child apneic events a rapidly decreased . Our experience suggests that distraction osteogenesis after careful preoperative evaluation can be successfully performed for the treatment of peripheral airway obstruction in patients with selected craniofacial anomalies ." ], "offsets": [ [ 0, 1487 ] ] } ]
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obstruction" ], "offsets": [ [ 95, 113 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001883" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 146, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "hypoplasia" ], "offsets": [ [ 177, 187 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543481" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 195, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tongue" ], "offsets": [ [ 239, 245 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153349" }, { "db_name": "UMLS", "db_id": "C0040408" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "osteogenesis" ], "offsets": [ [ 343, 355 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029433" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 360, 368 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "tongue" ], "offsets": [ [ 411, 417 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153349" }, { "db_name": "UMLS", "db_id": "C0040408" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "distraction osteogenesis" ], "offsets": [ [ 331, 355 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524975" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 454, 460 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 461, 469 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "hypoplasia" ], "offsets": [ [ 572, 582 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543481" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "airway obstruction" ], "offsets": [ [ 532, 550 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001883" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "All" ], "offsets": [ [ 621, 624 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023449" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "gastrostomy" ], "offsets": [ [ 639, 650 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017196" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "nutrition" ], "offsets": [ [ 713, 722 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0392209" }, { "db_name": "UMLS", "db_id": "C0028707" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 750, 757 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "tracheostomy" ], "offsets": [ [ 758, 770 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040590" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "birth" ], "offsets": [ [ 799, 804 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005615" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "child" ], "offsets": [ [ 849, 854 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "child" ], "offsets": [ [ 925, 930 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "sleep" ], "offsets": [ [ 963, 968 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037313" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "apnea" ], "offsets": [ [ 969, 974 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003578" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "sleep apnea" ], "offsets": [ [ 963, 974 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037315" } ] }, { "id": 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"C0029433" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "evaluation" ], "offsets": [ [ 1345, 1355 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220825" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 1394, 1403 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1440, 1448 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t5", "type": "umlsterm", "text": [ "anomalies" ], "offsets": [ [ 1476, 1485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000769" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t6", "type": "umlsterm", "text": [ "distraction osteogenesis" ], "offsets": [ [ 1293, 1317 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524975" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t7", "type": "umlsterm", "text": [ "airway obstruction" ], "offsets": [ [ 1418, 1436 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001883" } ] }, { "id": "MundKieferGesichtschirurgie.80020146.eng.abstr-s12-t8", "type": "umlsterm", "text": [ "craniofacial anomalies" ], "offsets": [ [ 1463, 1485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376634" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020153.eng.abstr
MundKieferGesichtschirurgie.80020153.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-passage-0", "type": "abstract", "text": [ "Cranial and cervical chordomas can spread by para- or retropharyngeal extension up to the region of the salivary glands or the jaw and may simulate a tumor of the salivary glands or jaw . In occasional cases , because the tumors often expand slowly , months or years may pass between the first clinical symptoms and diagnosis . Diagnostic problems exist in differentiating these chordomas from pleomorphic adenoma , mucinous carcinoma , or chondrosarcoma . Ten relevant observations of typical cranial and cervical chordomas ( Salivary Gland Register Hamburg 1965-1996 ) were analyzed more closely by pathohistological and immunohistochemical means . The exact diagnosis is based upon the evidence of blown-up , bubble-like ( \" physaliform \" ) cells which contain mucus drops in a vacuolized cytoplasm and are surrounded by extensive areas of mucoid mucus . The pattern of immunohistochemistry is characterized by the multifold expression of cytokeratin , vimentin , and EMA . The differential diagnosis is discussed with reference to further types of chordoma ( chondroid chordoma , dedifferentiated chordoma with spindle cell sarcomatous transformation ) , chondrosarcoma , pleomorphic adenoma , and mucus-producing carcinoma ." ], "offsets": [ [ 0, 1229 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "chordomas" ], "offsets": [ [ 21, 30 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "para-" ], "offsets": [ [ 45, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030563" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 127, 130 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 150, 155 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 182, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "salivary glands" ], "offsets": [ [ 104, 119 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036098" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "salivary glands" ], "offsets": [ [ 163, 178 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036098" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 222, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "symptoms" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 316, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Diagnostic" ], "offsets": [ [ 328, 338 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "chordomas" ], "offsets": [ [ 379, 388 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "adenoma" ], "offsets": [ [ 406, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001430" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 425, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "chondrosarcoma" ], "offsets": [ [ 440, 454 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008479" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "pleomorphic adenoma" ], "offsets": [ [ 394, 413 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026277" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "mucinous carcinoma" ], "offsets": [ [ 416, 434 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007130" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "observations" ], "offsets": [ [ 470, 482 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0302523" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "chordomas" ], "offsets": [ [ 515, 524 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "Register" ], "offsets": [ [ 542, 550 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600375" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "Salivary Gland" ], "offsets": [ [ 527, 541 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036098" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "exact" ], "offsets": [ [ 655, 660 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0059927" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 661, 670 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 744, 749 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "mucus" ], "offsets": [ [ 764, 769 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026727" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "cytoplasm" ], "offsets": [ [ 792, 801 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010834" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "mucus" ], "offsets": [ [ 850, 855 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026727" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "immunohistochemistry" ], "offsets": [ [ 873, 893 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021044" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "cytokeratin" ], "offsets": [ [ 942, 953 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010803" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "vimentin" ], "offsets": [ [ 956, 964 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042666" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 994, 1003 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "chordoma" ], "offsets": [ [ 1052, 1060 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "chordoma" ], "offsets": [ [ 1073, 1081 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "chordoma" ], "offsets": [ [ 1101, 1109 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008487" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 1123, 1127 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t6", "type": "umlsterm", "text": [ "chondrosarcoma" ], "offsets": [ [ 1159, 1173 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008479" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t7", "type": "umlsterm", "text": [ "adenoma" ], "offsets": [ [ 1188, 1195 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001430" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t8", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 1218, 1227 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t9", "type": "umlsterm", "text": [ "differential diagnosis" ], "offsets": [ [ 981, 1003 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220820" }, { "db_name": "UMLS", "db_id": "C0011906" } ] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t10", "type": "umlsterm", "text": [ "pleomorphic adenoma" ], "offsets": [ [ 1176, 1195 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026277" } ] } ]
[]
[]
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"MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t5", "arg2_id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t6", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-r22-t9.1-t10.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t9", "arg2_id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t10", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-r23-t1.1-t10.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t1", "arg2_id": "MundKieferGesichtschirurgie.80020153.eng.abstr-s7-t10", "normalized": [] } ]
MundKieferGesichtschirurgie.80020163.eng.abstr
MundKieferGesichtschirurgie.80020163.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020163.eng.abstr-passage-0", "type": "abstract", "text": [ "Malignant epithelioid schwannoma is a very rare disease originating from the Schwann cells . It is a subtype of malignant schwannoma . The limbs are the main location of this entity . In our case study , the inferior alveolar nerve was involved in the mandible . The prognosis for patients with this disease is poor , because metastasis occurs in more than 50% . Clinical and histological features and treatment in a 42-year-old man are discussed in detail . In addition , a short review of the literature and treatment recommendations are given ." ], "offsets": [ [ 0, 547 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020172.eng.abstr
MundKieferGesichtschirurgie.80020172.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-passage-0", "type": "abstract", "text": [ "Malignant lymphomas , hematological malignancies , sarcomas , occult head and neck primaries , Merkel cell carcinomas and malignant melanomas are among the tumors that are rarely seen in the head and neck region . Almost 20% of patients with acute leukemia initially present with symptoms of the oral cavity ( ulcerations , gingival hypertrophy , etc. ) . If a malignant lymphoma is suspected , the lymph node should be removed in toto to ascertain diagnosis . Furthermore , in order to make sure that the immunohistological work-up or electron microscopic analysis is adequate , the pathologist should be informed prior to extirpation of the suspicious lymph node . The same diagnostic procedure is indicated for metastases from undifferentiated or small cell cancer of an unknown primary . Metastatic squamous cell or undifferentiated carcinoma to a solitary cervical lymph node from an unknown primary can be cured by multimodal therapy ( extirpation , radical neck dissection and adjuvant radiation ) in 30% of the cases . Following polychemotherapy , long-term survival may also be achieved in disseminated stages of undifferentiated carcinoma or poorly differentiated adenocarcinoma in an occult primary . When osteosarcoma of the jaw is suspected , core biopsy has to be planned carefully : in order to prevent tumor seeding , the needle track has to be excised during definitive surgery . Most authors propose ( neo- ) adjuvant chemotherapy ( or chemoradiation ) for head and neck osteosarcoma , especially when additional risk factors , i.e. a large primary or poorly differentiated sarcoma , are present . Patients with positive margins should receive adjuvant radiotherapy in soft tissue sarcoma . Local control of angiosarcoma is possible exclusively by radiation . Adjuvant radiation is also indicated in Merkel cell carcinoma . Because this tumor spreads in a \" cascade \" fashion , elective node dissection may also provide a chance for cure . Excision with wide margins is the principal therapeutic step in malignant melanoma . Due to the anatomic localization , adequate resection may not be possible in mucosal melanoma of the head and neck . When regional lymph nodes are involved , radical lymph node dissection and adjuvant radiation have to be added to the therapeutic concept . There is an emerging role for adjuvant interferon alpha in intermediate and high-risk melanoma ." ], "offsets": [ [ 0, 2396 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Malignant" ], "offsets": [ [ 0, 9 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "lymphomas" ], "offsets": [ [ 10, 19 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024299" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "malignancies" ], "offsets": [ [ 36, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "sarcomas" ], "offsets": [ [ 51, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036210" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 69, 73 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 78, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 102, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 107, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "malignant" ], "offsets": [ [ 122, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "melanomas" ], "offsets": [ [ 132, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025202" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 156, 162 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "head" ], "offsets": [ [ 191, 195 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018670" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t13", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 200, 204 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t14", "type": "umlsterm", "text": [ "Malignant lymphomas" ], "offsets": [ [ 0, 19 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024299" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t15", "type": "umlsterm", "text": [ "hematological malignancies" ], "offsets": [ [ 22, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376545" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t16", "type": "umlsterm", "text": [ "Merkel cell" ], "offsets": [ [ 95, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205832" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t17", "type": "umlsterm", "text": [ "malignant melanomas" ], "offsets": [ [ 122, 141 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025202" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s1-t18", "type": "umlsterm", "text": [ "Merkel cell carcinomas" ], "offsets": [ [ 95, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007129" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 228, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "leukemia" ], "offsets": [ [ 248, 256 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023418" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "symptoms" ], "offsets": [ [ 280, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "ulcerations" ], "offsets": [ [ 310, 321 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041582" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "hypertrophy" ], "offsets": [ [ 333, 344 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020564" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "oral cavity" ], "offsets": [ [ 296, 307 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0226896" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "gingival hypertrophy" ], "offsets": [ [ 324, 344 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017567" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "malignant" ], "offsets": [ [ 361, 370 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "lymphoma" ], "offsets": [ [ 371, 379 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024299" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 399, 404 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "toto" ], "offsets": [ [ 431, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0169567" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 449, 458 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "malignant lymphoma" ], "offsets": [ [ 361, 379 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024299" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "lymph node" ], "offsets": [ [ 399, 409 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "electron" ], "offsets": [ [ 536, 544 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013852" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 557, 565 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 654, 659 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "lymph node" ], "offsets": [ [ 654, 664 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "diagnostic" ], "offsets": [ [ 676, 686 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 687, 696 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "metastases" ], "offsets": [ [ 714, 724 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 756, 760 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "cancer" ], "offsets": [ [ 761, 767 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Metastatic" ], "offsets": [ [ 792, 802 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 812, 816 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 837, 846 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 870, 875 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 932, 939 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 964, 968 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t7", "type": "umlsterm", "text": [ "dissection" ], "offsets": [ [ 969, 979 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012737" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t8", "type": "umlsterm", "text": [ "adjuvant" ], "offsets": [ [ 984, 992 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001551" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t9", "type": "umlsterm", "text": [ "radiation" ], "offsets": [ [ 993, 1002 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0851346" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t10", "type": "umlsterm", "text": [ "undifferentiated carcinoma" ], "offsets": [ [ 820, 846 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205698" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t11", "type": "umlsterm", "text": [ "lymph node" ], "offsets": [ [ 870, 880 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s6-t12", "type": "umlsterm", "text": [ "radical neck dissection" ], "offsets": [ [ 956, 979 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034542" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "polychemotherapy" ], "offsets": [ [ 1037, 1053 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013218" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "survival" ], "offsets": [ [ 1066, 1074 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220921" }, { "db_name": "UMLS", "db_id": "C0038952" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "stages" ], "offsets": [ [ 1112, 1118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027646" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 1139, 1148 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "adenocarcinoma" ], "offsets": [ [ 1174, 1188 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001418" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s7-t6", "type": "umlsterm", "text": [ "undifferentiated carcinoma" ], "offsets": [ [ 1122, 1148 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205698" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "osteosarcoma" ], "offsets": [ [ 1217, 1229 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029463" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "jaw" ], "offsets": [ [ 1237, 1240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022359" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "biopsy" ], "offsets": [ [ 1261, 1267 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 1318, 1323 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "needle" ], "offsets": [ [ 1338, 1344 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027551" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t6", "type": "umlsterm", "text": [ "track" ], "offsets": [ [ 1345, 1350 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040594" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s8-t7", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 1387, 1394 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "adjuvant" ], "offsets": [ [ 1427, 1435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001551" } ] }, { "id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s9-t2", 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"interacts_with", "arg1_id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s17-t4", "arg2_id": "MundKieferGesichtschirurgie.80020172.eng.abstr-s17-t3", "normalized": [] } ]
MundKieferGesichtschirurgie.80020181.eng.abstr
MundKieferGesichtschirurgie.80020181.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-passage-0", "type": "abstract", "text": [ "Objective : The lack of sensitivity and specificity of conventional imaging techniques based on morphological critera is responsible for considerable limitations in the staging and surveillance of oral cancer . Therefore , this study investigates the contribution of [ F18]-2-fluordesoxyglucose ( FDG ) positron emission tomography ( PET ) to tumor management with special regard to lymph-node involvement and therapeutic monitoring after radiotherapy . Design : Prospective observational study . Patients : Twenty-one patients with advanced oral cancer , predominantly T3/T4. Intervention : FDG-PET scans before and after preoperative radio ( chemo ) therapy . Standardized uptake values ( SUV ) were determined for the tumor site and lymph-node areas . PET scans were correlated to histological findings after ablative tumor surgery . Results : FDG-PET yielded superior sensitivity and specificity for tumor and lymph-node assessment . The effect of radiotherapy was reflected by the metabolic activity of the tumor , which shows a close correlation between the decrease of FDG uptake and histologic tumor regression . PET detected distant metastases and simultaneous tumors . Conclusion : FDG-PET is a challenging imaging technique with the potential to improve staging procedures for oral cancer . In the monitoring of metabolic activity of the tumor in the course of radio ( chemo ) therapy , FDG-PET allows objective measurement of the treatment response ." ], "offsets": [ [ 0, 1462 ] ] } ]
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}, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "morphological" ], "offsets": [ [ 96, 109 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543482" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "surveillance" ], "offsets": [ [ 181, 193 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220920" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "cancer" ], "offsets": [ [ 202, 208 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "imaging techniques" ], "offsets": [ [ 68, 86 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079595" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "oral cancer" ], "offsets": [ [ 197, 208 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153381" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "sensitivity and specificity" ], "offsets": [ [ 24, 51 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036668" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "positron" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032744" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "tomography" ], "offsets": [ [ 321, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040395" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "PET" ], "offsets": [ [ 334, 337 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031268" }, { "db_name": "UMLS", "db_id": "C0032743" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 343, 348 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "lymph-node" ], "offsets": [ [ 383, 393 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 410, 421 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "radiotherapy" ], "offsets": [ [ 439, 451 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034618" }, { "db_name": "UMLS", "db_id": "C0034619" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "positron emission tomography" ], "offsets": [ [ 303, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032743" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 497, 505 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 519, 527 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "cancer" ], "offsets": [ [ 547, 553 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "radio" ], "offsets": [ [ 636, 641 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034546" } ] }, { "id": "MundKieferGesichtschirurgie.80020181.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 652, 659 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": 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[]
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MundKieferGesichtschirurgie.80020188.eng.abstr
MundKieferGesichtschirurgie.80020188.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020188.eng.abstr-passage-0", "type": "abstract", "text": [ "Absorbed radiation doses delivered by computed tomography and panoramic radiography were measured in 16 anatomic sites using a head and neck phantom and thermoluminescent dosimetry . The recommended kilovoltage and scan time for dental scanning was reduced step by step , rating the quality of the low-dose scans . A reduction of up to 76% could be achieved without loss of diagnostic accuracy . Measured absorbed radiation dose ranges from 0.30 mGy ( thyroid ) to 29 mGy ( skin ) at 187,5 mAs and 1.0 mm-slices ( 25 mm scanning distance for maxilla , 30 mm for mandible ) . After reduction to 45 mAs , 0.07 mGy ( thyroid ) to 6.9 mGy ( skin ) was measured . Distance measurements on human jaw specimens were compared with corresponding CT image measurements . Average deviation was 0.1- 0.3 mm . A dose reduction of 75% had no effect on the results . However , the doses of CT-scans reduced by 76% exceed by an average factor of 10 the doses of conventional panoramic radiography . Therefore , CT should be reserved for the planning of complex implant treatment in the direct vicinity of the maxillar sinus and nerves and for multiple implant insertion ." ], "offsets": [ [ 0, 1155 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020202.eng.abstr
MundKieferGesichtschirurgie.80020202.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020202.eng.abstr-passage-0", "type": "abstract", "text": [ "Injuries of the nasoethmoid-orbital ( NEO ) region are associated with midfacial fractures or fractures of the frontobase in over 90% of all cases . In up to 70% fractures of the skull base run through the roof of the ethmoidal bone or the lamina cribrosa . There are different surgical approaches for the treatment of these complex fractures . Between 1990 and 1997 50 patients with midfacial fractures in association with NEO fractures were treated in the Klinik fuer Mund- , Kiefer- und Gesichtschirurgie , Kantonsspital Luzern , Switzerland . Of these , 25 had suffered midfacial fractures combined with fractures of the nasoethmoid-orbital and frontobasal region and were treated via a transcranial approach . The other 25 patients with midfacial and NEO fractures without involvement of the frontobasis were managed by subcranial incisions . A total of 47 patients were followed up for up to 4 years . The results were reevaluated retrospectively . There was no case of secondary liquorrhea , intracranial or ethmoidal infection . Our therapeutic concept of transcranial and subcranial management of NEO fractures in combination with frontobasal and midfacial fractures is demonstrated ." ], "offsets": [ [ 0, 1193 ] ] } ]
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MundKieferGesichtschirurgie.80020209.eng.abstr
MundKieferGesichtschirurgie.80020209.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-passage-0", "type": "abstract", "text": [ "The case of a 30-year-old patient is reported who presented with a right-sided amaurosis fugax and a simultaneous frontobasal fracture that had occurred after a fall . By CT angiography and MRI angiography obstruction of the ophthalmic artery following a dissection of the internal carotid artery with ascending thrombosis could be demonstrated . There was a lack of further neurological deficits because of sufficient perfusion of the cerebral arteries by the arterial circle of the cerebrum . Among the etiological variety of types of post-traumatic amaurosis , this rare cause should be taken into consideration in the etiology , diagnosis and therapy , if appropriate ." ], "offsets": [ [ 0, 673 ] ] } ]
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"C0002978" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "MRI" ], "offsets": [ [ 190, 193 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024485" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "angiography" ], "offsets": [ [ 194, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002978" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "artery" ], "offsets": [ [ 236, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003842" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "dissection" ], "offsets": [ [ 255, 265 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012737" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "artery" ], "offsets": [ [ 290, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003842" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "thrombosis" ], "offsets": [ [ 312, 322 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040053" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "MRI angiography" ], "offsets": [ [ 190, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243032" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "ophthalmic artery" ], "offsets": [ [ 225, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029078" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "carotid artery" ], "offsets": [ [ 282, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162859" }, { "db_name": "UMLS", "db_id": "C0007272" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "internal carotid artery" ], "offsets": [ [ 273, 296 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007276" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "perfusion" ], "offsets": [ [ 419, 428 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031001" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "arteries" ], "offsets": [ [ 445, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003842" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cerebrum" ], "offsets": [ [ 484, 492 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242202" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "cerebral arteries" ], "offsets": [ [ 436, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007770" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "amaurosis" ], "offsets": [ [ 552, 561 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376288" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "cause" ], "offsets": [ [ 574, 579 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "etiology" ], "offsets": [ [ 622, 630 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" }, { "db_name": "UMLS", "db_id": "C0007463" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 633, 642 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "MundKieferGesichtschirurgie.80020209.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 647, 654 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020213.eng.abstr
MundKieferGesichtschirurgie.80020213.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-passage-0", "type": "abstract", "text": [ "Two cases of unicystic ameloblastoma in the mandible of young children are described . Conservative surgery is justified in children due to the lower risk of recurrence compared to cases of solid ameloblastoma and the risk of growth disturbance after radical surgery . However , long-term follow-up is necessary ." ], "offsets": [ [ 0, 313 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "unicystic" ], "offsets": [ [ 13, 22 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0278076" }, { "db_name": "UMLS", "db_id": "C0063382" }, { "db_name": "UMLS", "db_id": "C0040188" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "ameloblastoma" ], "offsets": [ [ 23, 36 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002448" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 44, 52 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 62, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 100, 107 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 124, 132 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 150, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "recurrence" ], "offsets": [ [ 158, 168 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034897" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "ameloblastoma" ], "offsets": [ [ 196, 209 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002448" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "risk" ], "offsets": [ [ 218, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 226, 232 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 259, 266 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "risk of" ], "offsets": [ [ 150, 157 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "risk of" ], "offsets": [ [ 218, 225 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035647" } ] } ]
[]
[]
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[] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-r6-t1.2-t4.1", "type": "occurs_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-r7-t2.1-t4.1", "type": "occurs_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t2", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-r9-t1.2-t2.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s1-r10-t1.2-t2.1", "type": "diagnoses", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t2", "normalized": [] }, 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[] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r1-t4.1-t5.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r2-t4.1-t7.2", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r3-t4.1-t1.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r4-t5.1-t7.2", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r5-t5.1-t1.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r6-t5.1-t1.2", "type": "occurs_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r7-t5.1-t4.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t5", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r9-t7.1-t1.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "normalized": [] }, { "id": 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"MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r14-t7.1-t1.2", "type": "produces", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-r15-t1.2-t7.2", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t1", "arg2_id": "MundKieferGesichtschirurgie.80020213.eng.abstr-s2-t7", "normalized": [] } ]
MundKieferGesichtschirurgie.80020216.eng.abstr
MundKieferGesichtschirurgie.80020216.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020216.eng.abstr-passage-0", "type": "abstract", "text": [ "We report the case of a 77 year old woman with a giant proliferating trichilemmal cyst of the scalp and a central squamous-cell carcinoma . Six months after radical tumor-excision and dissection of the locoregionary lymph nodes the patient developed retroclavicular lymph node metastases . The tumor develops from cells of the hair matrix and tends to recur after excision ; in rare cases malignant transformation may occur . We suggest radical excision and complete histological examination of the tumor . In cases of malignancy , lymph node-dissection is sometimes necessary . In these cases close postoperative follow-up of the patient is mandatory ." ], "offsets": [ [ 0, 653 ] ] } ]
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"MundKieferGesichtschirurgie.80020216.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "squamous-cell" ], "offsets": [ [ 114, 127 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020216.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 128, 137 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020216.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "trichilemmal cyst" ], "offsets": [ [ 69, 86 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086809" } ] }, { "id": "MundKieferGesichtschirurgie.80020216.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "tumor-excision" ], "offsets": [ [ 165, 179 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020216.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "dissection" ], "offsets": [ [ 184, 194 ] ], "normalized": [ { "db_name": "UMLS", "db_id": 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[]
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MundKieferGesichtschirurgie.80020238.eng.abstr
MundKieferGesichtschirurgie.80020238.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-passage-0", "type": "abstract", "text": [ "It is still a matter of controversy whether anastomosis of the sensory nerves is necessary in free transplants of microvascular reanastomosed myocutaneous latissimus dorsi flaps in the oral cavity and oropharynx . Some surgeons perform this routinely because they expect fewer complications in skin with a sensory nerve supply . We clinically examined 30 patients in order to assess the sensory innervation of the transplant tissue . All patients received free transplants of microvascular reanastomosed latissimus dorsi flaps during a tumor operation in the oral cavity . Sensation was determined clinically according to pain , temperature , pressure , two point discrimination and vibration . In most patients sensation in the Latissimus dorsi flap does not return . These findings suggest that reinnervation in the myocutaneous latissimus dorsi flap mostly does not occur , indicating that there is a need for anastomosis of a sensory nerve during transplant surgery with a myocutaneous latissimus dorsi flap to reinnervate it ." ], "offsets": [ [ 0, 1031 ] ] } ]
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], "offsets": [ [ 185, 196 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0226896" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 277, 290 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 294, 298 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "nerve" ], "offsets": [ [ 314, 319 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027769" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "supply" ], "offsets": [ [ 320, 326 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243163" }, { "db_name": "UMLS", "db_id": "C0038848" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "nerve supply" ], "offsets": [ [ 314, 326 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021516" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 355, 363 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "innervation" ], "offsets": [ [ 395, 406 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021516" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "transplant" ], "offsets": [ [ 414, 424 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 425, 431 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "transplant tissue" ], "offsets": [ [ 414, 431 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0302296" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "All" ], "offsets": [ [ 434, 437 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023449" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 438, 446 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "transplants" ], "offsets": [ [ 461, 472 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "flaps" ], "offsets": [ [ 521, 526 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038925" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 536, 541 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "operation" ], "offsets": [ [ 542, 551 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "oral cavity" ], "offsets": [ [ 559, 570 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0226896" } ] }, { "id": "MundKieferGesichtschirurgie.80020238.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Sensation" ], "offsets": [ [ 573, 582 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036658" } ] }, { "id": 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MundKieferGesichtschirurgie.80020242.eng.abstr
MundKieferGesichtschirurgie.80020242.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020242.eng.abstr-passage-0", "type": "abstract", "text": [ "Formation of metastases was observed in 246 cases ( 27.8% ) out of a group of 884 patients with melanoma of the head and neck region treated in the years 1967-1991 . In the group of patients with metastases , regional metastases were found in the cervical lymph nodes in 136 cases ( 55.3% ) . In 74 patients ( 30.1% ) the first metastasis was a distant metastasis , i.e. , the tumor had spread by hematogenic dissemination . In 53 patients ( 21.5% ) the first metastasis was located in the parotid gland . Evaluation of the clinical data of the patients led to interesting results regarding prognosis following the different types of surgical treatment . The 5-year survival rates were established by means of multivariant analysis using the Cox model , taking into account sex and tumor thickness : Following radical tumor removal , including neck dissection and parotidectomy , the 5-year survival rate amounted to 61.8% . If the parotid gland was not removed and only tumor and cervical lymph nodes were resected , 66.2% of the patients were still alive 5 years following surgery . The difference between these two groups was statistically not significant ( P = 0.07 ) . In those cases where only the primary tumor was removed , the 5-year survival rate was 85.8% and thus significantly better than in the two other groups ( P = 0.0001 ) . Two conclusions can be drawn : In metastasizing melanoma of the head and neck the parotid glands are affected in 20% of the cases and thus more frequently than expected . The retrospective analysis of groups of patients differing with regard to the prognosis of their disease cannot be used to provide information on which therapy is the best . This is particularly true for the question whether or not the parotid gland should be removed in addition to a neck dissection . It will be necessary to perform a prospective randomized study in order to find answers to these questions . Such a study could be performed within DOeSAK ( Deutsch-Oesterreich-Schweizerischer Arbeitskreis fuer Tumoren im Mund-Kiefer-Gesichtsbereich = German , Austrian , Swiss Working Group on Tumors in the Maxillo-Facial Region ) in cooperation with different hospitals ." ], "offsets": [ [ 0, 2191 ] ] } ]
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"normalized": [] } ]
MundKieferGesichtschirurgie.80020250.eng.abstr
MundKieferGesichtschirurgie.80020250.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-passage-0", "type": "abstract", "text": [ "Tumour growth is directly related to the multiplication of tumour cell numbers which can be caused , firstly , by increased proliferation and , secondly , by prolongation of the life span of tumour cells . The aim was the quantification of the increase and decrease ( apoptosis ) in cell numbers in relation to the cytological grading of oral squamous epithelial cell carcinoma . Proof of apoptosis-specific fragmentation of DNA ( double-strand breaks ) by the TUNEL method ( TdT-mediated dUTP nick end labelling ) and of proliferative activity by the monoclonal antibody MIB 1 was found in 41 oral squamous epithelial carcinomas of different grading . With progression of the cytological grading , an increase of proliferative activity and a decrease of apoptotic activity occurs . The apoptosis rates were 13.5% for G1 carcinomas , 8.5% for G2 carcinomas and 6.1% for G3 carcinomas . The results confirm that during progression to higher malignant cellular phenotypes of oral squamous carcinoma , increased proliferative activity as well as reduced apoptosis rates contribute substantially to the multiplication of tumour cell numbers and show that during progression a loss of control of programmed cell death ( apoptosis ) occurs . However , the high standard deviations of apoptosis rates within the different grades disprove an individual prognostic significance ." ], "offsets": [ [ 0, 1370 ] ] } ]
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"db_id": "C0376558" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "tumour" ], "offsets": [ [ 191, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 198, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 210, 213 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "apoptosis" ], "offsets": [ [ 268, 277 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162638" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 283, 287 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 363, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 368, 377 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "epithelial cell" ], "offsets": [ [ 352, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014597" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "apoptosis-specific" ], "offsets": [ [ 389, 407 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0078040" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "apoptosis-specific" ], "offsets": [ [ 389, 407 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005745" }, { "db_name": "UMLS", "db_id": "C0033377" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "DNA" ], "offsets": [ [ 425, 428 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012854" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "TUNEL" ], "offsets": [ [ 461, 466 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0600528" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 467, 473 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "antibody" ], "offsets": [ [ 563, 571 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003241" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 619, 629 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "monoclonal antibody" ], "offsets": [ [ 552, 571 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003250" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "apoptotic" ], "offsets": [ [ 755, 764 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0078040" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "apoptosis" ], "offsets": [ [ 787, 796 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162638" } ] }, { "id": "MundKieferGesichtschirurgie.80020250.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 821, 831 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": 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[]
[]
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MundKieferGesichtschirurgie.80020256.eng.abstr
MundKieferGesichtschirurgie.80020256.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020256.eng.abstr-passage-0", "type": "abstract", "text": [ "Because tumour cell invasion is a three-dimensional process involving tumour cells as well as stromal cells , tumour invasion models should include equivalents of both compartments in a spatially defined organisation . Aims : Evaluation of differentiation and invasive potential in relation to basement membrane ( BM ) formation of new human oral squamous cell carcinoma ( OSCC ) cell lines under the influence of fibromatosis fibroblasts in a 3D co-culture system ( collagen type I/fibroblast-containing matrix ) . Material and methods : OSCC cell lines were established and cultured on collagen type I matrix with and without the inclusion of fibro-/myofibroblasts derived from nodular palmar fibromatosis ) . Evaluation of invasion was done by conventional H & E staining after paraffin embedding ; immunohistochemistry was performed for cytokeratins ( MNF 116 ) , involucrin ( Sy5), vimentin ( V9), collagen type IV ( CIV22), laminin ( 1-chain , 4C7), and Ki-67 ( MIB1); and electron microscopy followed . Results : The OSCC cell lines PE/CA-PJ15, PE/CA-PJ34, PE/CA-PJ41 were invasive exclusively on gels containing fibroblasts with stratification of the multilayerd OSCC cell coat and polarised expression of cytokeratin and involucrin . There was no evidence for BM , either by immunohistochemistry or by electron microscopy , although OSCC are immunohistochemically positive for collagen type IV and laminin in the 2D cell culture . There were no differences in proliferative activity of the gels with and without fibroblasts . Conclusions : Carcinoma cell invasion depends on the presence of fibroblasts in the gel indicating the important role of tumor stromal fibro-/myofibroblasts during carcinomic invasion . The absence of a BM does not , per se , imply an invasive tumour growth . Moreover , stratification and terminanl differentiation of epithelial tumour cells occur independently of a structural BM ." ], "offsets": [ [ 0, 1918 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020261.eng.abstr
MundKieferGesichtschirurgie.80020261.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-passage-0", "type": "abstract", "text": [ "A possible correlation between the thermal effects of the weather and the frequency of odontogenic soft-tissue infections was investigated with special regard to the so-called felt temperature ( gT ) . Clinical data of 2111 patients of the years 1992-1996 in whom an incision was made because of an odontogenic soft-tissue infection were evaluated retrospectively and correlated to meteorological data for Aachen , collected or calculated by the \" Deutsche Wetterdienst \" . In order to describe the thermal exchange between the human organism and the surroundings in a satisfactory way , the gT was chosen . The gT is a complexly calculated meteorological parameter which allows physiologically adequate estimation of the thermic surroundings of humans ." ], "offsets": [ [ 0, 754 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "weather" ], "offsets": [ [ 58, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043085" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 74, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "infections" ], "offsets": [ [ 111, 121 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "temperature" ], "offsets": [ [ 181, 192 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039476" }, { "db_name": "UMLS", "db_id": "C0005903" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 224, 232 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 323, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 528, 533 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "organism" ], "offsets": [ [ 534, 542 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029235" } ] }, { "id": "MundKieferGesichtschirurgie.80020261.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "humans" ], "offsets": [ [ 746, 752 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020270.eng.abstr
MundKieferGesichtschirurgie.80020270.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-passage-0", "type": "abstract", "text": [ "One case of a newly described , rare odontogenic tumor is reported . A literature review of 19 cases lends support to the odontogenic origin and metastatic capability , both regionally and distantly , of the clear cell odontogenic tumor . We conclude that this tumor is malignant , with a tendency to recur locally after surgery . It requires an aggressive surgical approach and should be referred to as a clear cell odontogenic carcinoma . In our patient we saw a clear cell odontogenic carcinoma and a squamous cell carcinoma , both with regional lymph node metastasis . The histological differentiation of this type of tumor from other clear cell tumors is difficult ." ], "offsets": [ [ 0, 671 ] ] } ]
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}, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "metastatic" ], "offsets": [ [ 145, 155 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036525" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 214, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 231, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "literature review" ], "offsets": [ [ 71, 88 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0282441" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "odontogenic tumor" ], "offsets": [ [ 219, 236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": 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"normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 429, 438 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 448, 455 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 471, 475 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 488, 497 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 513, 517 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 518, 527 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 549, 554 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "metastasis" ], "offsets": [ [ 560, 570 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "lymph node" ], "offsets": [ [ 549, 559 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s5-t9", "type": "umlsterm", "text": [ "squamous cell carcinoma" ], "offsets": [ [ 504, 527 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 622, 627 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 645, 649 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020270.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "tumors" ], "offsets": [ [ 650, 656 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.80020275.eng.abstr
MundKieferGesichtschirurgie.80020275.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020275.eng.abstr-passage-0", "type": "abstract", "text": [ "Basal cell adenocarcinoma was first introduced as an entity in the second edition of the WHO's \" Histologic Typing of Salivary Gland Tumours \" in 1991. This tumor was first described in 1990 by Ellis and Wiskovitch from the Armed Forces Institute of Pathology ( AFIP ) . Basal cell adenocarcinoma accounts for about 2.9% of all salivary gland malignancies . More than 90% of the tumors are situated in the parotid gland . Intraoral manifestations are known from case reports only . Tumors of the palate have been mentioned in three cases . Histologically this tumor can be easily confused with basal cell adenoma and the solid basaloid subtype of adenoid cystic carcinoma . The case presented here is a middle-aged white woman with a basal cell adenocarcinoma of the palate . Therapy consisted of surgical extirpation with three-dimensional safety margins and histologically proven clear resection margins . Knowledge at this point indicates that basal cell adenocarcinoma has a rather high probability of local recurrence ( up to 50% ) and a mostly lymphogenous metastatic potential for as long as 10 years after removal of the primary tumor . Ten year survival is around 75% ." ], "offsets": [ [ 0, 1178 ] ] } ]
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MundKieferGesichtschirurgie.80020279.eng.abstr
MundKieferGesichtschirurgie.80020279.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-passage-0", "type": "abstract", "text": [ "A 63-year-old man is presented in whom a tenosynovial giant-cell tumor destroyed the right temporomandibular joint and fossa and showed extensive intracranial growth . Because of uncharacteristic complaints , a symptomatic treatment was performed elsewhere . The lesion was finally resected under endotracheal anesthesia . After 20 months free of recurrence the patient's outcome is very satisfying . Differential diagnosis and therapy are discussed ." ], "offsets": [ [ 0, 451 ] ] } ]
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[]
[]
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"normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r14-t3.1-t7.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t3", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r16-t1.2-t7.1", "type": "measurement_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r17-t7.2-t3.1", "type": "surrounds", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t3", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r18-t5.1-t1.2", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t5", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r19-t4.1-t7.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t4", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r20-t3.1-t5.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t3", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r21-t5.1-t7.1", "type": "location_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t5", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-r22-t7.1-t4.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t7", 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"MundKieferGesichtschirurgie.80020279.eng.abstr-s1-t4", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-r2-t1.1-t2.1", "type": "precedes", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-r3-t1.2-t2.1", "type": "precedes", "arg1_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t1", "arg2_id": "MundKieferGesichtschirurgie.80020279.eng.abstr-s5-t2", "normalized": [] } ]
MundKieferGesichtschirurgie.80020309.eng.abstr
MundKieferGesichtschirurgie.80020309.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020309.eng.abstr-passage-0", "type": "abstract", "text": [ "Johann Friedrich Dieffenbach ( 1792-1847 ) is generally known as the founder of modern plastic surgery . One focus of his work , apart from the physiology of transplantation and operative techniques , was reconstructive oral and maxillofacial surgery . This special aspect of plastic surgery as well as Dieffenbach's biography is presented in this historic article ." ], "offsets": [ [ 0, 366 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.80020316.eng.abstr
MundKieferGesichtschirurgie.80020316.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-passage-0", "type": "abstract", "text": [ "Recent studies have shown that acute infections , especially of the respiratory tract , are an important risk factor for cerebral ischemia . Additionally we know that chronic dental infections may be a risk for myocardial infarction and artherosclerosis . However , the connection between stroke and dental infections has hardly been examined so far . Therefore we performed a case-control study using a standardized questionaire and examination . We investigated 66 patients consecutive to a acute cerebral ischemia/stroke and 60 age- and sex-matched nonstroke neurological patients as a control group . Dental status was determined by a so called total dental index ( TDI ) which reflects primarily caries , periodontitis , periapical lesions , devital and missing teeth as well as by a panoramic index ( PI ) . Specifically , older patients with cerebrovascular ischemia tended to have a significantly worse dental status and had more severe periodontitis and periapical lesions than control subjects . A predefined poor dental status was associated with cerebrovascular ischemia independent from other vascular risk factors and social status . In conclusion , poor dental health , mainly resulting from chronic dental infections , may be associated with an increased risk for cerebrovascular ischemia . The results must now be verified in larger studies . As chronic dental infections are a common and also easily treatable factor , their identification as a risk factor for stroke would be quite important in the field of preventive medicine ." ], "offsets": [ [ 0, 1548 ] ] } ]
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"arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r22-t2.1-t1.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r23-t4.1-t6.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t4", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t6", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r24-t2.1-t5.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t5", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r25-t4.1-t2.1", "type": "result_of", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t4", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r26-t1.1-t8.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t8", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r27-t6.2-t4.1", "type": "diagnoses", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t6", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-r28-t3.1-t5.1", "type": "issue_in", "arg1_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t3", "arg2_id": "MundKieferGesichtschirurgie.80020316.eng.abstr-s11-t5", "normalized": [] } ]
MundKieferGesichtschirurgie.80020320.eng.abstr
MundKieferGesichtschirurgie.80020320.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-passage-0", "type": "abstract", "text": [ "The regeneration of the oral mucosa is zinc- and vitamin A-pathway dependent . Hyperkeratoses , a disturbed immune system and a higher incidence of oral malignancies have been reported in cases of deficiency . In this study , blood samples were taken from 97 patients with oral lichen planus , oral leukoplakia , oral squamous cell carcinoma ( OSCC ) , and a control group . Besides routine blood analysis , serum levels of zinc ( Zn ) , vitamin A ( Vit A ) and retinol binding protein ( RBP ) were identified . Mean values in lichen ruber planus were Zn 784 µg/l, RBP 5.26 mg/dl and Vit A 656 ng/ml ; in leukoplakia Zn 696 µg/l, RBP 5.30 mg/dl and Vit A 652 ng/ml ; and in OSCC Zn 659 µg/l, RBP 5.00 mg/dl and Vit A 617 ng/ml . Patients with lichen ruber planus showed no statistically significant differences , whereas in leukoplakia patients there were statistically lower values for Zn compared to the control group and the lichen ruber planus group ( P 0.05 ) . Patients with oral malignancies showed lower serum levels for Zn , RBP and Vit A. Compared with the control group and the lichen ruber planus group , differences of the serum Zn levels proved to be statistically significant ( P 0.01 ) . In patients with oral leukoplakia and patients with oral carcinoma and Zn deficiency , a substitutional therapy should be considered ." ], "offsets": [ [ 0, 1338 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "regeneration" ], "offsets": [ [ 4, 16 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034963" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "mucosa" ], "offsets": [ [ 29, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026724" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "zinc-" ], "offsets": [ [ 39, 44 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043481" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "vitamin" ], "offsets": [ [ 49, 56 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042890" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "oral mucosa" ], "offsets": [ [ 24, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026639" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "incidence" ], "offsets": [ [ 135, 144 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220856" }, { "db_name": "UMLS", "db_id": "C0021149" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "malignancies" ], "offsets": [ [ 153, 165 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "deficiency" ], "offsets": [ [ 197, 207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011155" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "immune system" ], "offsets": [ [ 108, 121 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020962" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 226, 231 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 259, 267 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 278, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "planus" ], "offsets": [ [ 285, 291 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 299, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 327, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 332, 341 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 359, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "lichen planus" ], "offsets": [ [ 278, 291 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t10", "type": "umlsterm", "text": [ "oral leukoplakia" ], "offsets": [ [ 294, 310 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023532" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t11", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 359, 372 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t12", "type": "umlsterm", "text": [ "oral lichen planus" ], "offsets": [ [ 273, 291 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0206139" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s3-t13", "type": "umlsterm", "text": [ "squamous cell carcinoma" ], "offsets": [ [ 318, 341 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 391, 396 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "analysis" ], "offsets": [ [ 397, 405 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002778" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "zinc" ], "offsets": [ [ 424, 428 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043481" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "vitamin" ], "offsets": [ [ 438, 445 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042890" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "retinol" ], "offsets": [ [ 462, 469 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042839" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "binding" ], "offsets": [ [ 470, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243122" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "protein" ], "offsets": [ [ 478, 485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033684" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "RBP" ], "offsets": [ [ 488, 491 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035342" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t9", "type": "umlsterm", "text": [ "vitamin A" ], "offsets": [ [ 438, 447 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042839" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t10", "type": "umlsterm", "text": [ "binding protein" ], "offsets": [ [ 470, 485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242210" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s4-t11", "type": "umlsterm", "text": [ "retinol binding protein" ], "offsets": [ [ 462, 485 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035342" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "values" ], "offsets": [ [ 517, 523 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042295" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 527, 533 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "planus" ], "offsets": [ [ 540, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "RBP" ], "offsets": [ [ 565, 568 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035342" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 605, 616 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "RBP" ], "offsets": [ [ 630, 633 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035342" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "RBP" ], "offsets": [ [ 692, 695 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035342" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "ruber planus" ], "offsets": [ [ 534, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s5-t9", "type": "umlsterm", "text": [ "lichen ruber planus" ], "offsets": [ [ 527, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 729, 737 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 743, 749 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "planus" ], "offsets": [ [ 756, 762 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 824, 835 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 836, 844 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "values" ], "offsets": [ [ 876, 882 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042295" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t7", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 906, 913 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t8", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 928, 934 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t9", "type": "umlsterm", "text": [ "planus" ], "offsets": [ [ 941, 947 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032074" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t10", "type": "umlsterm", "text": [ "ruber planus" ], "offsets": [ [ 750, 762 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t11", "type": "umlsterm", "text": [ "control group" ], "offsets": [ [ 906, 919 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009932" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t12", "type": "umlsterm", "text": [ "ruber planus" ], "offsets": [ [ 935, 947 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t13", "type": "umlsterm", "text": [ "lichen ruber planus" ], "offsets": [ [ 743, 762 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s6-t14", "type": "umlsterm", "text": [ "lichen ruber planus" ], "offsets": [ [ 928, 947 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023646" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 967, 975 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "malignancies" ], "offsets": [ [ 986, 998 ] ], 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[]
[]
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"MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t4", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-r22-t5.1-t1.1", "type": "occurs_in", "arg1_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t5", "arg2_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-r23-t6.1-t2.1", "type": "associated_with", "arg1_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t6", "arg2_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-r24-t2.1-t3.1", "type": "occurs_in", "arg1_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t2", "arg2_id": "MundKieferGesichtschirurgie.80020320.eng.abstr-s8-t3", "normalized": [] } ]
MundKieferGesichtschirurgie.80020326.eng.abstr
MundKieferGesichtschirurgie.80020326.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-passage-0", "type": "abstract", "text": [ "Objective : The Uppsala-definition of leukoplakia has recently redefined oral leukoplakia . Based on this definition , the aim of our study was to reevaluate the prevalence of oral leukoplakia in patients with histologically proven primary oral cancer . Design : A total of 101 inpatients in four tumor centers in Berlin were interviewed and clinically examined just prior to surgery of an oral squamous cell carcinoma ( OSCC ) . Results : The prevalence of leukoplakia immediately adjacent to the carcinoma was 15.8% . Additional leukoplakias without relation to the carcinoma were found in 4% of the patients . There were no significant differences in age- or sex-distribution , history of tobacco habits or diet between patients with or without leukoplakia . T1 carcinomas were found in 62.5% of patients with , and 24.4% of patients without associated leukoplakia , whereas a balanced distribution was found for the pre-operative staging of the tumor . Conclusions : The prevalence of oral leukoplakia in patients with OSCC was low , compared to retrospective studies . The presence or absence of leukoplakia indicated no influence on the prognosis of the tumor , except of tumor size . The results emphasize that most OSCC develop from healthy appearing oral mucosa ." ], "offsets": [ [ 0, 1272 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Objective" ], "offsets": [ [ 0, 9 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018017" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 38, 49 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 78, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "oral leukoplakia" ], "offsets": [ [ 73, 89 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023532" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "aim" ], "offsets": [ [ 123, 126 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0108800" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "prevalence" ], "offsets": [ [ 162, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220900" }, { "db_name": "UMLS", "db_id": "C0033105" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "leukoplakia" ], "offsets": [ [ 181, 192 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023531" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 196, 204 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "proven" ], "offsets": [ [ 225, 231 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700164" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "cancer" ], "offsets": [ [ 245, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "oral leukoplakia" ], "offsets": [ [ 176, 192 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023532" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "oral cancer" ], "offsets": [ [ 240, 251 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0153381" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "inpatients" ], "offsets": [ [ 278, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021562" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tumor" ], "offsets": [ [ 297, 302 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "Berlin" ], "offsets": [ [ 314, 320 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005125" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 376, 383 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 404, 408 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 409, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "squamous cell carcinoma" ], "offsets": [ [ 395, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "MundKieferGesichtschirurgie.80020326.eng.abstr-s4-t1", 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[]
[]
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MundKieferGesichtschirurgie.80020331.eng.abstr
MundKieferGesichtschirurgie.80020331.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-passage-0", "type": "abstract", "text": [ "Up to now the clinical follow-up in mandibular callus distraction was supported by radiologic methods , although low-mineralized structures are only insufficiently described by X-rays . Mandibular callus distraction was performed on 14 patients suffering from uni- or bilateral mandibular hypoplasia , using either intra- or extraoral devices . The clinical follow-up was supplemented by standardized sonographic investigations . With the exception of postoperative pin placement control , which was done by using X-rays , all interesting items of treatment could be visualized by sonography . We found a reliable correlation between sonographically measured distances and distances measured on the device . Due to early detection of complications , a premature ossification was detected in one case and an infection was diagnosed in another , using ultrasound . Sonography proved to enhance the possibilities of monitoring in mandibular callus distraction treatment and can be recommended in clinical routine ." ], "offsets": [ [ 0, 1011 ] ] } ]
[ { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "callus" ], "offsets": [ [ 47, 53 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376154" }, { "db_name": "UMLS", "db_id": "C0006767" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "methods" ], "offsets": [ [ 94, 101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "X-rays" ], "offsets": [ [ 177, 183 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043309" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "callus" ], "offsets": [ [ 197, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376154" }, { "db_name": "UMLS", "db_id": "C0006767" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 236, 244 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "hypoplasia" ], "offsets": [ [ 289, 299 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543481" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "devices" ], "offsets": [ [ 335, 342 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 452, 465 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "pin" ], "offsets": [ [ 466, 469 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175718" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "control" ], "offsets": [ [ 480, 487 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243148" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "X-rays" ], "offsets": [ [ 514, 520 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043309" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 548, 557 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "sonography" ], "offsets": [ [ 581, 591 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041618" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "distances" ], "offsets": [ [ 659, 668 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012751" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "distances" ], "offsets": [ [ 673, 682 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012751" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "device" ], "offsets": [ [ 699, 705 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0699733" }, { "db_name": "UMLS", "db_id": "C0220819" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "complications" ], "offsets": [ [ 734, 747 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009566" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 807, 816 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "ultrasound" ], "offsets": [ [ 850, 860 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220934" }, { "db_name": "UMLS", "db_id": "C0041618" }, { "db_name": "UMLS", "db_id": "C0041621" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "callus" ], "offsets": [ [ 938, 944 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376154" }, { "db_name": "UMLS", "db_id": "C0006767" } ] }, { "id": "MundKieferGesichtschirurgie.80020331.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 957, 966 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.8002s008.eng.abstr
MundKieferGesichtschirurgie.8002s008.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s008.eng.abstr-passage-0", "type": "abstract", "text": [ "On 27 June 1899 Rudolf Virchow ( 1821-1902 ) inaugurated the Museum of Pathology at the Charité Hospital . The collection comprised 23 500 pathologic-anatomical specimens . Most of the collection was destroyed in World War II . About 2000 samples were saved . Meanwhile the stock has increased to about 9000 objects . The development , contents and structure of the famous Virchow Collection are described with special reference to craniofacial deformities ." ], "offsets": [ [ 0, 458 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.8002s016.eng.abstr
MundKieferGesichtschirurgie.8002s016.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s016.eng.abstr-passage-0", "type": "abstract", "text": [ "Median craniofacial clefts are classified as median facian cleft deformities and are characterized by clefts of the nose involving the skull base . They can be accompanied by hypertelorism and/or encephaloceles . From a total of 22 of our patients with median deformities , three encephaloceles and two severe median nasal clefts with hypertelorism were considered in 2-to-8-year-olds. Two children with severe brain deformities died before the commencement of therapy . The remaining median deformities were corrected as soon as possible , whereby exclusively soft-tissue surgery was performed during the first year of life and in no case later than school admittance . Final corrections on the nasal skeleton were made after the age of 12. No growth disturbances of the middle face or jaw occurred subsequent to craniotomies and corrections of hypertelorism . Plate osteosynthesis has proven to be the most reliable method of stabilization ; we removed the osteosynthetic material in all cases . The multiplicity of possible deformities requires that procedures be tailored to the individual case ." ], "offsets": [ [ 0, 1100 ] ] } ]
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MundKieferGesichtschirurgie.8002s020.eng.abstr
MundKieferGesichtschirurgie.8002s020.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s020.eng.abstr-passage-0", "type": "abstract", "text": [ "The standardised operational techniques of fronto-orbital osteotomy and the various modifications used today make it possible to perform extensive surgery for the treatment of craniofacial malformations and advanced tumours in this region , while also allowing for a good extra- and intracranial view . Osteotomies and resections in areas of the skull base that are normally hard to reach have been considerably facilitated and the operational risk has been lowered . Our aim is to achieve a further reduction of the operational risks and of the post-surgical morbidity rate through the use of techniques of computer-assisted surgery . Especially in the area of the complex anatomy of the skull base , use of the systems for the purpose of orientation and realisation of operational planning as well as for the control of how radical a tumour resection needs to be , have proved quite successful . Meanwhile , we have acquired experience in more than 100 clinical applications of mechanical and optoelectronical navigation systems . However , it is not possible to make changes to the presurgical data . Also , the flexibility of the system is still somewhat limited . By introducing a new referencing system , the flexibility and possible applications of navigation have been increased . The current possibilities and indications for the use of intraoperative navigation are discussed ." ], "offsets": [ [ 0, 1387 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.8002s029.eng.abstr
MundKieferGesichtschirurgie.8002s029.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s029.eng.abstr-passage-0", "type": "abstract", "text": [ "The development of frontal sinuses following bilateral fronto-orbital advancement is a topic of controversial discussion in the literature . In a retrospective study on 33 patients ( 15 girls and 18 boys ) the development of the frontal sinus was examined radiologically . Only patients with a minimum age of 6 years and with at least 1 year of postoperative follow-up were included . The radiological reference for the frontal sinus development consisted of pneumatisation at or above the level of the supraorbital rims , as projected in postero-anterior cephalograms . According to these criteria a frontal sinus development was seen in 72.7% of our patients . There was no statistically proven correlation between sinus development and the sex of the patient , age at surgery or the amount of advancement . With the exception of severe cases of Crouzon's disease we usually expect normal development of the frontal sinus following bilateral fronto-orbital correction ." ], "offsets": [ [ 0, 971 ] ] } ]
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[]
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MundKieferGesichtschirurgie.8002s032.eng.abstr
MundKieferGesichtschirurgie.8002s032.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-passage-0", "type": "abstract", "text": [ "Autolyzed , antigen-extracted , allogeneic bone ( AAA bone ) is prepared from cortical bones of human organ donors . AAA bone possesses osteoinductive properties as it delivers BMPs from its bone matrix . Within a prospective study , 37 cranial defects were reconstructed using AAA bone implants over a period of more than 7 years . The patients were followed-up at standardized intervals . Roentgenographic assessments and bone scintigraphies revealed osseous integration and remodelling of the AAA bone implants . In one quarter of the cases re-entry was performed 10 to 18 months after the cranioplasty ( removal of osteosynthesis material , recurrence of tumor ) . All nine AAA bone reconstructions showed bleeding surfaces and bony integrations . A bone biopsy was taken from the center of one of these AAA bone implants and this showed new bone formation originating from the surface of the implant . In one case an AAA bone implant was lost due to infection . This is noteworthy as in approximately one third of the cases the bone implants were in direct contact with the frontal sinus . The clinical results clearly emphasize the therapeutical benefit of AAA bone for cranioplasties . Large AAA bone chips from human skull bones facilitate the reconstruction of the skull's convexity , especially when sterolithography-based operation planning is performed ." ], "offsets": [ [ 0, 1366 ] ] } ]
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1203, 1207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "human" ], "offsets": [ [ 1219, 1224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020114" } ] }, { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "skull" ], "offsets": [ [ 1225, 1230 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037303" } ] }, { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-s12-t4", "type": "umlsterm", "text": [ "bones" ], "offsets": [ [ 1231, 1236 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-s12-t5", "type": "umlsterm", "text": [ "skull's" ], "offsets": [ [ 1274, 1281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037303" } ] }, { "id": "MundKieferGesichtschirurgie.8002s032.eng.abstr-s12-t6", "type": "umlsterm", "text": [ "skull's" ], 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[]
[]
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MundKieferGesichtschirurgie.8002s037.eng.abstr
MundKieferGesichtschirurgie.8002s037.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-passage-0", "type": "abstract", "text": [ "A new stoechiometric mixture of 27% dicalcium-phosphate ( DCPA ) and 73% tetra-calcium-phosphate ( TTCP ) can be prepared with water intraoperatively to a paste that subsequently sets to a structurally stabile implant composed of hydroxyapatite ( HA ) . Primary setting time is about 20 min ; pH during setting ranges from 6.5 to 8.5. There is no relevant curing heat or expansion or contraction . Compressive strength is about 50 MPa , tensile strength about 8 MPa . Over a period of about 4 h in physiological milieu , the cement converts to hydroxyapatite . This product is no longer redissolvable in normal body fluid . This cement can be used for non-load-bearing applications especially in craniofacial bone surgery . Cranial defects due to tumour or trauma as well as deficits in the facial skeleton may be reconstructed using this new biomaterial . In nine of ten patients we used the hydroxyapatite cement successfully for reconstructions in the craniofacial area . Fluid control of the operation field and implant site is extremely important and sometimes difficult to achieve . Further applications could be all non-load-bearing augmentations such as filling of blocked paranasal sinuses , of dentoalveolar cysts and defects following dental apectomy or fixation of implanted hearing-aid electrodes . The perspectives for the hydroxyapatite cement include its application as a carrier for osteogenic protein preparations , especially because of its isothermic reaction and intrinsic osteoconductive characteristics ." ], "offsets": [ [ 0, 1527 ] ] } ]
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"UMLS", "db_id": "C0020311" }, { "db_name": "UMLS", "db_id": "C0043047" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "paste" ], "offsets": [ [ 155, 160 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030634" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "hydroxyapatite" ], "offsets": [ [ 230, 244 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020326" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "time" ], "offsets": [ [ 270, 274 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040223" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "heat" ], "offsets": [ [ 363, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018843" }, { "db_name": "UMLS", "db_id": "C0018837" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Compressive strength" ], "offsets": [ [ 398, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376507" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tensile strength" ], "offsets": [ [ 437, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039526" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "period" ], "offsets": [ [ 475, 481 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025344" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "hydroxyapatite" ], "offsets": [ [ 544, 558 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020326" } ] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "body fluid" ], "offsets": [ [ 611, 621 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005889" } ] }, { "id": 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[]
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"MundKieferGesichtschirurgie.8002s037.eng.abstr-s10-r35-t8.1-t2.1", "type": "degree_of", "arg1_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s10-t8", "arg2_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-r1-t2.2-t1.1", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t2", "arg2_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t1", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-r2-t1.1-t2.1", "type": "affects", "arg1_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t2", "normalized": [] }, { "id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-r5-t1.1-t2.2", "type": "interacts_with", "arg1_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t1", "arg2_id": "MundKieferGesichtschirurgie.8002s037.eng.abstr-s11-t2", "normalized": [] } ]
MundKieferGesichtschirurgie.8002s041.eng.abstr
MundKieferGesichtschirurgie.8002s041.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s041.eng.abstr-passage-0", "type": "abstract", "text": [ "In 12 patients with craniosynostosis the influence of early fronto-orbital advancement on the growth of the frontal sinus and supraorbital region was examined . A follow-up examination at the age of 8 years showed a lack of pneumatisation of about 50% . However , there was no correlation between this score and the external contour . The frontal sinus has no dominant influence on the growth of the supraorbital region . In 9 out 12 of cases the very early operation time did not lead to disturbances of growth . A further follow-up examination of the patients after termination of growth at the age of 16 is planned ." ], "offsets": [ [ 0, 619 ] ] } ]
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[]
[]
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MundKieferGesichtschirurgie.8002s044.eng.abstr
MundKieferGesichtschirurgie.8002s044.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s044.eng.abstr-passage-0", "type": "abstract", "text": [ "A retrospective and partly prospective study was conducted to analyse both clinically and cephalometrically the craniofacial growth pattern of patients with isolated and syndrome-related premature craniosynostosis after standardized fronto-orbital and midface advancement . The file data of 293 children with fronto-orbital advancement were evaluated over an average period of 4.4 years . In addition , lateral teleradiographies of 117 patients from this group were cephalometrically analysed . Moreover , late results of 36 children and 8 adults with midface-advancement with an average follow-up period of 4.5 years were assessed . In contrast to linear craniectomy and so-called lateral canthal advancement , in only 8.2% of cases ( 24 out of 293 patients ) were relapses requiring reoperation found in this study after fronto-orbital advancement . The evaluations indicate that with simple forms of craniosynostosis such as trigonocephaly and plagiocephaly predominantly very good or good growth can be observed . Cephalometric evaluation confirmed the limited potential of growth in the area of the anterior skull base and in the midface in the presence of syndrome-related faciocraniosynostoses . In such cases the cephalometrically confirmed maxillary hypoplasia , which increases in severity in the following order of syndromes `Saethre-Chotzen-Crouzon-Apert-Pfeiffer', could be influenced only to a limited degree by fronto-orbital advancement . For this reason midface advancement is of secondary importance in children with very severe anomalies . In the present evaluation , a high rate of relapse of midfacial hypoplasia was to be found in children and adolescents after this operation in accordance with other references . Therefore , the indication for Le Fort III osteotomy in the growth period should be limited ." ], "offsets": [ [ 0, 1830 ] ] } ]
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[]
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MundKieferGesichtschirurgie.8002s049.eng.abstr
MundKieferGesichtschirurgie.8002s049.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-passage-0", "type": "abstract", "text": [ "Craniofacial development may be potentially implicated after vault corrections in cases of craniosynostosis . The aim of this prospective study was the investigation of the surgical effect on calvaria growth , correlating the percentiles of a group of patients before and after craniosynostosis correction in relation to the normal percentiles of growth . The patient population consisted of 71 children ; the postoperative follow-up time in 57 patients was more than 12 months . Of the children followed up , 36 were male and 21 female . Thirty-six cases involved untreated non-syndromic craniosynostosis ; the remaining 21 were syndrome cases . The patient ages ranged from 16 to 27 months . In 11 cases correction of an occipital craniosynostosis was carried out . The fronto-occipital circumference was registered in accordance with Prader's percentile table . The operative method included a fronto-parietal craniotomy , the temporary removal and shaping of the fronto-orbital band and a vault cranioplasty . During follow-up 13 patients treated with fronto-orbital advancement in cases of isolated craniosynostosis remained in the registered percentile curve . In 13 patients a change to a lower percentile curve was confirmed ; 1 patient changed to a higher curve . In cases of syndromic craniosynostosis 10 patients remained in the post-operatively registered percentile curve ; 8 patients changed to a lower and 1 patient to a higher percentile curve . No growth restriction of the reshaped calvaria after surgical correction of craniosynostosis was observed . No significant difference was found in the potential calvaria growth between syndromic and isolated craniosynostosis ." ], "offsets": [ [ 0, 1688 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0205950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 201, 207 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 252, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 278, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 347, 353 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "prospective study" ], "offsets": [ [ 126, 143 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033522" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 360, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "population" ], "offsets": [ [ 368, 378 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032659" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 395, 403 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "postoperative" ], "offsets": [ [ 410, 423 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032790" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "time" ], "offsets": [ [ 434, 438 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040223" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 445, 453 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 487, 495 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "male" ], "offsets": [ [ 518, 522 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024554" }, { "db_name": "UMLS", "db_id": "C0086582" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 530, 536 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 589, 605 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 630, 638 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 651, 658 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "ages" ], "offsets": [ [ 659, 663 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001792" }, { "db_name": "UMLS", "db_id": "C0001811" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 733, 749 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 879, 885 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "craniotomy" ], "offsets": [ [ 913, 923 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010280" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1034, 1042 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 1104, 1120 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1173, 1181 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 1237, 1244 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s12-t1", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 1295, 1311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s12-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1315, 1323 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s12-t3", "type": "umlsterm", "text": [ "patients" ], 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"MundKieferGesichtschirurgie.8002s049.eng.abstr-s13-t4", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 1538, 1554 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s14-t1", "type": "umlsterm", "text": [ "calvaria" ], "offsets": [ [ 1623, 1631 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s14-t2", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 1632, 1638 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.8002s049.eng.abstr-s14-t3", "type": "umlsterm", "text": [ "craniosynostosis" ], "offsets": [ [ 1670, 1686 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010278" } ] } ]
[]
[]
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MundKieferGesichtschirurgie.8002s052.eng.abstr
MundKieferGesichtschirurgie.8002s052.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-passage-0", "type": "abstract", "text": [ "The treatment of syndromic hypoplasias of the midfacial complex , for example in Crouzon patients , is necessary at an early stage for functional and aesthetic reasons . If midfacial advancement is done by the traditional technique using bone grafts , it has often been seen that the normal occlusion originally achieved changes in an Angle class III , because the mandible grows regularly but not the midface . This problem could probably be solved if midfacial advancement is done by the gradual callus-distraction procedure . The local osteogenesis involves the possibility that there is normal growth of the midfacial complex even if the operation is performed in young children . Based on experience in mandibular bone lengthening , this new method was used in a 10-year-old Crouzon patient . As successful lengthening of the midface needs a stable device and a reliable base , a new midfacial distractor was designed using the principle of the halo-frame . With an advancement of about 22 mm the midfacial position was normalized and a regular overbite was achieved . In a case report the new technique is shown and the results are demonstrated and discussed . Despite this encouraging early result a long-term follow-up is not yet possible ." ], "offsets": [ [ 0, 1248 ] ] } ]
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"db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 238, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "grafts" ], "offsets": [ [ 243, 249 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "mandible" ], "offsets": [ [ 365, 373 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024687" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "bone grafts" ], "offsets": [ [ 238, 249 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005976" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "Angle class III" ], "offsets": [ [ 335, 350 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024639" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "callus-distraction" ], "offsets": [ [ 498, 516 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376154" }, { "db_name": "UMLS", "db_id": "C0006767" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "procedure" ], "offsets": [ [ 517, 526 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "osteogenesis" ], "offsets": [ [ 539, 551 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029433" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 598, 604 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "operation" ], "offsets": [ [ 642, 651 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543467" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "children" ], "offsets": [ [ 674, 682 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008059" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "bone" ], "offsets": [ [ 719, 723 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0262950" } ] }, { "id": "MundKieferGesichtschirurgie.8002s052.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "method" ], "offsets": [ [ 747, 753 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025663" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": 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[]
[]
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MundKieferGesichtschirurgie.8002s063.eng.abstr
MundKieferGesichtschirurgie.8002s063.eng.abstr
[ { "id": "MundKieferGesichtschirurgie.8002s063.eng.abstr-passage-0", "type": "abstract", "text": [ "The coronal incision is a versatile approach to midface or skull base fractures . It allows the open reduction of complex fracture sites and facilitates canthopexy , marginotomy or calvarian bone harvesting . By this method , primary treatment can be optimised and the rate of secondary corrective surgery can be reduced . All trauma patients who underwent this kind of intervention were re-examined to check functional and aesthetic results . The complication rate was low and the advantages of these techniques are evident , so that it is suggested that the indication for this operative approach should be extended ." ], "offsets": [ [ 0, 619 ] ] } ]
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[]
[]
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