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ORP1L regulates dynein clustering on endolysosmal membranes in response to cholesterol levels
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cell biology
|
Quantifying the dynamics of viral recombination during free virus and cell-to-cell transmission in HIV-1 infection
|
evolutionary biology
|
Blocking the Rac1-TRPC5 pathway protects human podocytes
|
cell biology
|
Different combinations of insect Na,K-ATPase α- and β-subunit paralogs enable fine tuning of toxin resistance and enzyme kinetics
|
evolutionary biology
|
Genetics of phosphorus use efficiency in a MAGIC wheat population grown in the field
|
plant biology
|
Neural vulnerability and hurricane-related media are associated with post-traumatic stress in youth
|
neuroscience
|
Evolution of Single Gyroid Photonic Crystals in Bird Feathers
|
evolutionary biology
|
Learning Distance-Dependent Motif Interactions: An Explicitly Interpretable Neural Model of Genomic Events
|
bioinformatics
|
Chance, contingency, and necessity in the experimental evolution of ancestral proteins
|
evolutionary biology
|
Protein Phosphatase 1 in association with Bud14 inhibits mitotic exit in Saccharomyces cerevisiae
|
cell biology
|
Rest is Required to Learn an Appetitively-Reinforced Operant Task in Drosophila
|
neuroscience
|
Organisation of afferents along the anterior-posterior and medial-lateral axes of the rat OFC
|
neuroscience
|
The subcellular architecture of the xyl gene expression flow of the TOL catabolic plasmid of Pseudomonas putida mt-2
|
microbiology
|
Natural selection and the advantage of recombination
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evolutionary biology
|
Full-length de novo protein structure determination from cryo-EM maps using deep learning
|
bioinformatics
|
Using Neutralization Landscapes to enumerate Antibody Behavior and Decompose Antibody Mixtures
|
immunology
|
Natural enemies have inconsistent impacts on the coexistence of competing species
|
ecology
|
Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts
|
bioengineering
|
Identifying seaweeds species of Chlorophyta, Phaeophyta and Rhodophyta using DNA barcodes
|
plant biology
|
Cellxgene VIP unleashes full power of interactive visualization and integrative analysis of scRNA-seq, spatial transcriptomics, and multiome data
|
bioinformatics
|
Real-time single-cell characterizationof the eukaryotic transcription cyclereveals correlations between RNAinitiation, elongation, and cleavage
|
biophysics
|
Imaging transmembrane dynamics of biomolecules at live cell plasma membranes using quenchers in extracellular environment
|
biophysics
|
Capitalizing on paradoxical activation of the MAPK pathway for treatment of Imatinib-resistant mast cell leukemia and chronic myelogenous leukemia
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cancer biology
|
Head-Direction Coding in the Hippocampal Formation of Birds
|
neuroscience
|
DARPP-32 Distinguishes a Subset of Adult-Born Neurons in Zebra Finch HVC
|
neuroscience
|
A Population Receptive Field Model of the Magnetoencephalography Response
|
neuroscience
|
Serotonergic Effects on Interoception
|
neuroscience
|
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
|
neuroscience
|
Polygenic Scores for Plasticity: A New Tool for Studying Gene-Environment Interplay
|
genetics
|
Anatomy, transcription dynamics and evolution of wheat ribosomal RNA loci deciphered by a multi-omics approach
|
genomics
|
Multi-regional module-based signal transmission in the mouse visual cortex
|
neuroscience
|
cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space
|
neuroscience
|
RetroCHMP3 Blocks Budding of Enveloped Viruses Without Blocking Cytokinesis
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immunology
|
A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV
|
evolutionary biology
|
Subfunctionalisation of paralogous genes and evolution of differential codon usage preferences: the showcase of polypyrimidine tract binding proteins
|
evolutionary biology
|
Feedback from retinal ganglion cells to the inner retina
|
neuroscience
|
A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage
|
cell biology
|
DNA methylation signatures of duplicate gene evolution in angiosperms
|
plant biology
|
Transcriptional kinetic synergy: a complex landscape revealed by integrating modelling and synthetic biology
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systems biology
|
AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation
|
biochemistry
|
Sex change in aquarium systems establishes the New Zealand spotty wrasse (Notolabrus celidotus) as a temperate model species for the investigation of sequential hermaphroditism
|
physiology
|
Genome-wide identification of tomato xylem sap fitness factors for three plant-pathogenic Ralstonia species
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microbiology
|
Database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging data
|
neuroscience
|
Identification of activity-induced Egr3-dependent genes reveals genes associated with DNA damage response and schizophrenia
|
neuroscience
|
The spectrum of covariance matrices of randomly connected recurrent neuronal networks
|
neuroscience
|
Strategies of grain number determination differentiate barley row-types
|
plant biology
|
Molecular and evolutionary mechanisms of yeast thermotolerance
|
evolutionary biology
|
VeTra: a tool for trajectory inference based on RNA velocity
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bioinformatics
|
Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density
|
neuroscience
|
mtDNA replication in dysfunctional mitochondria promotes deleterious heteroplasmy via the UPRmt
|
cell biology
|
Stochastic survival of the densest and mitochondrial DNA clonal expansion in ageing
|
genetics
|
The actin nucleator Spir-1 is a virus restriction factor that promotes IRF3 activation
|
microbiology
|
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.
|
cell biology
|
Maintaining robust size across environmental conditions through plastic growth dynamics
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evolutionary biology
|
RecT recombinase expression enables efficient gene editing in Enterococcus
|
microbiology
|
Rabaptin5 targets autophagy to damaged early endosomes and Salmonella containing vacuoles by interaction with FIP200 and ATG16L1
|
cell biology
|
Mosquito sound communication: are male swarms loud enough to attract females?
|
ecology
|
Tree-Aggregated Predictive Modeling of Microbiome Data
|
bioinformatics
|
Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis
|
biochemistry
|
High Throughput Computational Mouse Genetic Analysis
|
bioinformatics
|
Resetting of 24-nt siRNA landscape is initiated before the first zygotic division in rice
|
plant biology
|
Gradual development of non-adjacent dependency learning during early childhood
|
neuroscience
|
Meaningful Effects in the Adolescent Brain Cognitive Development Study
|
neuroscience
|
Ca2+ and Membrane Potential Transitions During Action Potentials are Self-Similar to Each Other and to Variability of AP Firing Intervals Across the Broad Physiologic Range of AP Intervals During Autonomic Receptor Stimulation
|
biophysics
|
Efficient Spline Regression for Neural Spiking Data
|
neuroscience
|
A Human Multi-Lineage Hepatic Organoid Model for Liver Fibrosis
|
cell biology
|
Human belief state-based exploration and exploitation in an information-selective symmetric reversal bandit task
|
neuroscience
|
ASO-based PKM Splice-switching Therapy Inhibits Hepatocellular Carcinoma Cell Growth
|
cancer biology
|
Striatal Direct Pathway Targets Npas1+ Pallidal Neurons
|
neuroscience
|
Experimentally disambiguating models of sensory cue integration
|
neuroscience
|
Investigating post-breeding moult locations and diets of Common Guillemots (Uria aalge) in the North Sea using stable isotope analyses
|
ecology
|
Fine-scale spatial patterns of wildlife disease are common and understudied
|
ecology
|
Gains and Losses Affect Learning Differentially at Low and High Attentional Load
|
animal behavior and cognition
|
Feature-based encoding of face identity by single neurons in the human amygdala and hippocampus
|
neuroscience
|
Spatial distribution of Arctic bacterioplankton abundance is linked to distinct water masses and summertime phytoplankton bloom dynamics (Fram Strait, 79°N)
|
microbiology
|
Homeostatic brain network mechanisms facilitate perceptual binding of audio-visual speech
|
neuroscience
|
No evidence for entrainment: endogenous gamma oscillations and rhythmic flicker responses coexist in visual cortex
|
neuroscience
|
Accurate spliced alignment of long RNAsequencing reads
|
bioinformatics
|
Evolution Without Variation and Selection
|
evolutionary biology
|
The Effect of Population Structure on Murine Genome-Wide Association Studies
|
genetics
|
Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies
|
genetics
|
Synthetic mammalian signaling circuits for robust cell population control
|
synthetic biology
|
Temporal variabilities provide additional category-related information in object category decoding: a systematic comparison of informative EEG features
|
neuroscience
|
Rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK) targets glucocorticoid receptor signaling: a longitudinal cerebrospinal fluid proteome study
|
neuroscience
|
Re-examining Kozlov et al.: Estimation of biases in museum specimen data requires robust sampling
|
ecology
|
Cellular aging in vitro recapitulates multi-tissue epigenetic aging in vivo
|
pathology
|
Evolution and regulation of microbial secondary metabolism
|
systems biology
|
Sunday driver mediates multi-compartment Golgi outposts defects induced by amyloid precursor protein
|
neuroscience
|
MetaFunc: Taxonomic and Functional Analyses of High Throughput Sequencing for Microbiomes
|
bioinformatics
|
Graph Convolutional Network-based Method for ClusteringSingle-cell RNA-seq Data
|
bioinformatics
|
Simulating the outcome of amyloid treatments in Alzheimer's Disease from multi-modal imaging and clinical data
|
bioinformatics
|
A mesh microelectrode array for non-invasive electrophysiology within neural organoids
|
neuroscience
|
Migration without interbreeding: evolutionary history of a highly selfing Mediterranean grass inferred from whole genomes
|
evolutionary biology
|
The need for high-quality oocyte mitochondria at extreme ploidy dictates germline development
|
evolutionary biology
|
mTOR inhibition represses transcription of cholesterol biosynthesis genes and alters cholesterol levels in primary neurons and in the developing brain
|
neuroscience
|
Epithelial and neutrophil interactions and innate immune response to Shigella in a human intestinal enteroid-neutrophil co-culture
|
immunology
|
The dirty north: Evidence for multiple colonisations and Wolbachia infections shaping the genetic structure of the widespread butterfly Polyommatus icarus in the British Isles
|
evolutionary biology
|
preciseTAD: A transfer learning framework for 3D domain boundary prediction at base-pair resolution
|
bioinformatics
|
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells
|
immunology
|
Preliminary report of preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates, SK-01 version 1 and OZG-3861 version 1
|
immunology
|
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