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5,700 |
Volume contents
| null |
5,701 |
Subject index, volumes 48–53
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5,702 |
Virus infections of rodents and lagomorphs: edited by A.D.M.E. Osterhaus, Elsevier, 1994, 432 pp, ISBN 0-444-81909-6, US$ 225.75, Dfl. 395.00
| null |
5,703 |
Virus infections of ruminants: Z. Dinter and B. Morein (Editors). Elsevier Science Publishers, 1990, 572 pp., hardcover, Dfl 380/$194.75, ISBN 0-444-87312-0
| null |
5,704 |
Contents of veterinary microbiol, volume 48
| null |
5,705 |
Contents of veterinary microbiology, volume 20
| null |
5,706 |
Contents of veterinary microbiology, volume 58
| null |
5,707 |
Contents of veterinary microbiology, volume 22
| null |
5,708 |
Author Index, Volumes 98-104
| null |
5,709 |
Volume contents
| null |
5,710 |
Contents of Veterinary microbiology, volume 19
| null |
5,711 |
Volume contents
| null |
5,712 |
Contents of veterinary microbiology, volume 26
| null |
5,713 |
Virus infections of porcines: 283 pp, Price US$ 142/Dfl.270, Elsevier Science Publishers, 1989. ISBN 0-444-42909-3
| null |
5,714 |
Microbiology of animals and animal products: Edited by J.B. Woolcock, 1991, Elsevier Science Publishers, 278 pp., hardcover, Dfl 275/$157.25, ISBN 0-444-43010-5.
| null |
5,715 |
Contents Vol. 42, 1994
| null |
5,716 |
Antigenicity of structural components from porcine transmissible gastroenteritis virus
|
Pregnant sows were inoculated with inactivated transmissible gastroenteritis virus and with preparations of virus surface projections and subviral particles derived by detergent treatment of the virus. Neutralising antibody was demonstrated in serum and colostrum from animals that received whole virus or preparations of surface projections whereas subviral particles failed to stimulate neutralising antibody formation. Similar results were obtained with serum from rabbits inoculated with whole virus and structural components. All three preparations stimulated the formation of agglutinating antibodies, as demonstrated by sedimentation analysis and filtration studies with radiolabelled virus. The immunoglobulin classes responsible for neutralising antibody activity in sows inoculated by the intramammary route were examined. In each case where the immunoglobulin class was determined, IgG was found. One sow that received surface projections also had IgA with neutralising activity in her colostrum. In contrast, infection of sows with live whole virus resulted in neutralising antibody of the IgG, IgM and IgA classes.
|
5,717 |
Contents of veterinary microbiology, volume 37
| null |
5,718 |
Hematologic and Biochemical Changes in Hospitalized Patients With Middle East Respiratory Syndrome-Coronavirus
| null |
5,719 |
Prevalence of Respiratory Viruses, Including Influenza, Among Nursing Home Residents and High-Touch Room Surfaces
| null |
5,720 |
Comparison of the Reproductive Numbers of Middle East Respiratory Syndrome Coronavirus Nosocomial Outbreaks in Saudi Arabia and Korea
| null |
5,721 |
A Prospective Study Comparing Self-Collected Nasal Swabs to Oral Washes for Monitoring Viral Load Kinetics in Lung Transplant Recipients With Respiratory Virus Infection
| null |
5,722 |
Differences in Self-Reported Severity of Symptoms Between Women and Men Experiencing Influenza-Like Illness
| null |
5,723 |
Role of Respiratory Virus Panels in Antimicrobial Stewardship in Immunocompromised Patients
| null |
5,724 |
Neutrophil Activation in Infants Hospitalized With Severe Respiratory Viral Infection
| null |
5,725 |
Clinical Significance of Human Coronavirus in Bronchoalveolar Lavage Samples From Hematopoietic Cell Transplantation Recipients and Hematologic Malignancy Patients
| null |
5,726 |
Quality of Life Among Survivors of Middle East Respiratory Syndrome Corona Virus
| null |
5,727 |
Laboratory-Confirmed Human Coronavirus Infections Among Children: Does Type Matter?
| null |
5,728 |
Prevalence of Respiratory Viral Pathogen Testing and Co-Detections Among Patients Hospitalized With Influenza, 2012–2015
| null |
5,729 |
Acute Respiratory Infections (ARIs) Among Outpatient Healthcare Personnel (HCP)
| null |
5,730 |
Low Co-infection Rate in Children With Community-Acquired Pneumonia in Spain
| null |
5,731 |
Drug repurposing strategies for COVID-19
|
COVID-19 has now been declared a pandemic and new treatments are urgently needed as we enter a phase beyond containment. Developing new drugs from scratch is a lengthy process, thus impractical to face the immediate global challenge. Drug repurposing is an emerging strategy where existing medicines, having already been tested safe in humans, are redeployed to combat difficult-to-treat diseases. While using such repurposed drugs individually may ultimately not yield a significant clinical benefit, carefully combined cocktails could be very effective, as was for HIV in the 1990s; the urgent question now being which combination.
|
5,732 |
Congenital malaria: rare but potentially fatal
|
Congenital malaria is rare and usually indolent but can be fatal. Mortality risk is high in newborns with Plasmodium falciparum born to nonimmune women, who typically present at birth or soon thereafter. Semi-immune women are less likely to transmit malaria, and their children often become ill weeks after delivery with less severe symptoms. Cases in the USA usually trace to semi-immune immigrant mothers whose last exposure to malaria may have preceded the pregnancy, leading to misdiagnoses. Congenital malaria may be under-recognized in malaria-endemic areas since parasitemia occurring after the first week of life is usually attributed to mosquito transmission. Malaria prophylaxis and the absence of fever during pregnancy do not preclude congenital malaria in a newborn. Quinine plus clindamycin is commonly used to treat P. falciparum congenital malaria, and chloroquine is used to treat other malaria parasites, such as Plasmodium vivax. Severe cases should be managed with intravenous quinine (available as its enantiomer quinidine in the USA) or with intravenous artesunate, which was recently approved for investigational use by the US FDA. Primaquine is not required for infants with congenital P. vivax or Plasmodium ovale, but should be offered to their mothers after excluding G6PD deficiency.
|
5,733 |
855 Double Blind Placebo Controlled Food Challenge Useful to Disconfirm Over Estimated Diagnosis of Cmpa in Children
|
Background and aims: The incidence of CMPA in infancy seems to be approximately 3%. In Italy diagnosis of CMPA is often over estimated. The double-blind, placebo controlled food challenge(DBPCFC) is widely considered as the “gold standard” for the diagnosis of food allergy. Methods: 14 patients, (12 months-12 yrs) previously diagnosed as having CMPA, underwent our diagnostic algorithm in order to confirm or to exclude diagnosis. Diagnostic algorithm includes: total blood cell count, serum IgE assay, RAST, betalactotest, Prick by prick with fresh milk, chemical examination and eosinophilic cell count of the stools. DBPCFC was performed with extensively hydrolyzed formula (as placebo) VS a lactose-free, cow milk derived formula. At discharge a post challenge form was given to parents to record delayed symptoms that might occur at home. Results: 12 out of 14 patients had positive results for skin prick test (prick by prick) and four out of them also presented specific IgE against CMPs. 13 patients showed tolerance to CMP during and after DBPCFC and had no symptoms also in the next 72h. Only one patient, aged 30 months, had to keep CMP avoidance. Conclusion: In our survey DBPCFC demonstrated tolerance to CMP for all but one patients. DBPCFC is effective also to disconfirm diagnosis of CMPA. Skin prick tests and serological specific IgE do not always correlate with oral tolerance test. Subjects with positive skin prick test and high serological specific IgE against CMP but tolerant at DBPCFC may reintroduce cow milk proteins in to their dietary meals.
|
5,734 |
856 Etiology of Bronchiolitis in a Hospitalized Pediatric Population: Prospective Multicenter Study
|
Background and aims: In 2006, bronchiolitis due to adenovirus nosocomial infections resulted in the closure of a pediatric department in northern Portugal. Objectives: To determine the etiology of bronchiolitis in northern Portugal. Methods: It was a prospective multicenter study on the etiology of bronchiolitis during the respiratory syncytial virus (RSV) season (November-April). Children ≤24 months of age admitted for a first wheezing episode were included. Nasopharyngeal specimens were analyzed by an indirect immunofluorescentantibody assay (IFA) for RSV, adenovirus (HAdV), parainfluenza (PIV) 1-3 and influenza (IV)Aand B and by polymerase chain reaction (PCR) or reverse transcription-PCR for the same viruses and for human metapneumovirus (hMPV), bocavirus (HBoV), rhinovirus (HRV), coronaviruses (229/E; NL63; OC43; HKU1) and enterovirus. Results: During this period, 253 children were included, 249 IFA analyses and 207 PCRs were performed. IFA detected RSV in 58.1%; PCR increased it to 66.7%. IFA detected HAdV in 3.2%, PCR 10.0%. PCR detected IV A in 5; IV B in 2; PIV 1 in 6, PIV 2 in 4 and PIV 3 in 11 cases. HBoV, as single agent in 2 cases, and HRV were positive in 8 samples and hMPV in 11. With this virus panel, 19.7% remained without etiology. Conclusions: The most frequent agent was RSV, followed by HAdV. PCR can be cost-effective and more accurate than IFA, which is crucial for HAdV that may be associated with significant mortality (IFA alone did not detect 2/3 of the cases).
|
5,735 |
Infections diverses
| null |
5,736 |
Ebola et autres, ces virus venus d’ailleurs
|
In the last decade, we faced a large number of emerging pathogens. As a consequence we had to adapt our medical practice as well as our health system. This review summarizes the main features of the recent emerging pathogens with a particular focus on the recent and ongoing Ebola outbreak, we tried to evaluate the consequences on our national health management.
|
5,737 |
Quels prélèvements aux urgences pour le diagnostic microbiologique d’une infection pulmonaire communautaire grave du sujet immunocompétent ?
|
Current diagnostic methods allow microbial identification in 50% of patients admitted with severe community-acquired pneumonia (CAP). Guidelines derived from epidemiological data help physicians to start empirical antimicrobial therapy. Definitive microbial diagnosis is useful to guide further pathogen-directed therapy. Blood cultures, cultures of respiratory specimens and urine antigen tests are recommended to determine the causative bacterial pathogen. Positive blood cultures range from 15 to 25% of CAP patients according to severity. Whether sputum specimens represent or not lower respiratory secretions determines its accuracy in CAP microbial diagnosis. In intubated patients, endotracheal aspirates are often of interest. Detection of positive pneumococcal or legionella urinary antigen is often associated with CAP severity. The sensitivity of this test is not decreased in patients who have received antibiotics prior to sampling. Viral pneumonia account for 10 to 40% of severe CAP. Nasal swabs are recommended for influenza identification using polymerase chain reaction (PCR) in order to deliver oseltamivir treatment. In the emergency department, atypical pneumonia serology is less useful than respiratory specimens obtained using fiberoptic bronchoscopy. Serum PCR to diagnose bacterial CAP is not superior to the other usual methods.
|
5,738 |
La modulation de la signature transcriptomique de l’hôte infecté : une nouvelle stratégie thérapeutique dans les viroses graves ? Exemple de la grippe
|
During the last decades, emergence and reemergence of viruses were responsible for epidemic and pandemic infectious diseases, with variable degrees of severity. Current preventive strategies are not sufficient at all, and available therapeutic drugs are very limited. Indeed, genetic variations of viruses can impair the efficacy of antiviral compounds by the apparition of resistance. Moreover, current delay needed for de novo development of drugs does not allow a rapid response in case of important epidemic or pandemic events. In this context, new therapeutic approaches are necessary. An innovative concept is to repurpose already marketed compounds that can reverse the host cellular transcriptomic response to the infection. By targeting the host, these molecules exhibit a broad-spectrum activity and are potentially effective even against new emergent strains. This strategy implements the characterization of specific host gene expression profiles, the in silico screening of drugs, and their validation in in vitro and in vivo models, until their evaluation in clinical trials. Here, we will present this approach, with the example of the flu.
|
5,739 |
Diagnostics en pathologie infectieuse
| null |
5,740 |
Infections respiratoires virales à herpesviridae en réanimation
|
Herpesviridae, including herpes simplex virus (HSV) and cytomegalovirus (CMV), are commonly detected in the respiratory tract of non-immunocompromised patients receiving mechanical ventilation. Although their detection usually involves viral reactivation without the involvement of pulmonary tissue, viral lung disease may occur in a particular population of patients. Although histological examination for specific cytopathic effects forms the basis of diagnosis, the use of modern virological tests (amplification using real-time polymerase chain reaction to estimate the vial load) should replace the histological tests in the near future. HSV bronchopneumonitis is associated with the reactivation of HSV in oropharyngeal and oral-labial lesions. It seems to clearly affect patients’ outcome due to prolonged mechanical ventilation and length of stay in the intensive care unit (ICU). However, only interventional studies will be able to determine its real impact. To date, use of acyclovir in these patients remains to be assessed. Although CMV reactivation in the blood is frequent in ICU patients, CMV pneumonia is difficult to diagnose because of the cumbersomeness of the procedure (open lung biopsies). Its true prognosis remains uncertain. The use of ganciclovir in this subset of patients also remains to be assessed.
|
5,741 |
Place des micro-organismes atypiques et des virus dans les pneumonies aiguës communautaires sévères
|
Usually, intensivists do not focus on atypical bacteria and viruses in severe community-acquired pneumonia (CAP). Only Legionella pneumophila and influenza virus, following the recent H1N1 influenza pandemic, are routinely suggested as responsible agents. However, CAP due to atypical bacteria may represent up to 44% of all CAP. Viral CAP is considered less severe than the usual bacterial ones, although 25% of them warrant hospitalization and 15% result in severe sepsis. Even though L. pneumophila is the most frequently atypical pathogen involved in severe cases, Mycoplasma pneumoniae may be responsible for multiorgan failure. To date, tools including detection of Legionella antigen in urine and Mycoplasma using polymerase chain reaction (PCR) allow rapid and accurate diagnosis. The treatment is based on macrolides and fluoroquinolones that can be associated in severe Legionnaire diseases. The presence of virus in CAP, either alone or in association with bacteria, has been demonstrated using molecular biology tests. These techniques also allowed the identification of several new viruses in CAP. However, the exact role of these detected viruses in CAP as well as the efficiency of antiviral therapy still represent major unsolved concerns.
|
5,742 |
Grippe A (H1N1)
| null |
5,743 |
Grippe A (H1N1) en réanimation
| null |
5,744 |
Grippe A (H1N1): donn’ees des r’eseaux
| null |
5,745 |
ECMO veinoveineuse
| null |
5,746 |
Insuffisance respiratoire aiguë : terrains particuliers
| null |
5,747 |
Postępy w rozpoznawaniu, diagnostyce laboratoryjnej i leczeniu chorób zakaźnych w ciągu stulecia 1908–2008()
| null |
5,748 |
The prevention and control of nosocomial infections: it is time for renewed emphasis and efforts: Proceedings of the 7th international BODE hygiene days, 15–17 May 2003, Tarragona (Barcelona), Spain
| null |
5,749 |
Emergency department dental care
| null |
5,750 |
LB-S&T-36 RECOVERY FROM NEUROLOGIC IMPAIRMENT IN MURINE MODEL OF CORONAVIRUS-INDUCED DEMYELINATION DOES NOT DIRECTLY CORRELATE WITH IMPROVEMENT OF NEUROGENIC BLADDER DYSFUNCTION: LONG-TERM FOLLOW UP STUDY
| null |
5,751 |
Self assessment/CPD answers
| null |
5,752 |
Effects of viral respiratory infections on lung development and childhood asthma
| null |
5,753 |
Role of Src in VEGF mediating the activation of rabbit osteoclasts in vitro
| null |
5,754 |
Staphylococcal and streptococcal infections
| null |
5,755 |
Community Acquired Respiratory Viral Infections (CARV) in Patients with Acute Leukemia and Hematopoietic Stem Cell Transplant (HSCT) Recipients
| null |
5,756 |
OR.18. VLA-4-Dependent Recruitment of Effector Memory CD8+T Lymphocytes into the Central Nervous System
| null |
5,757 |
Emerging infections and their causative agents
| null |
5,758 |
The role of the nervous system in rhinitis
| null |
5,759 |
The improvement of porcine epidemic diarrhea vaccine production by stimulating agents
| null |
5,760 |
Infectious complications following Venetoclax-Proteasome Inhibitor based regimens in relapsed myeloma: a single center retrospective analysis
| null |
5,761 |
Travel Medicine, Check Program of Self Assessment Unit 387, Vol. 2; Bruce Short (Ed.), 1st ed.; The Royal Australian College of General Practitioners, South Melbourne, May 2004, 33 pages, Paperback, ISSN 0812-9630
| null |
5,762 |
An Informal Discussion of Emergency Nurses' Current Clinical Practice: What's New and What Works
| null |
5,763 |
An informal discussion ofemergency nurses' current clinical practice: What's new and what works()()()
| null |
5,764 |
One-Teaming:: Gaining a Competitive Edge through Rapid Team Formation and Deployment
| null |
5,765 |
Beyond Our Pages
| null |
5,766 |
The diagnostic and prognostic significance of relative lymphopenia in adult patients with influenza A
| null |
5,767 |
This Month in AJP
|
The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology.
|
5,768 |
SUBJECT INDEX: VOLUME 134, 2003
| null |
5,769 |
AUTHOR INDEX, volumes 123-130
| null |
5,770 |
J. Virol. Methods: Erratum to “Detection of human coronavirus 229E-specific antibodies using recombinant fusion proteins” [55 (1995) 175]
| null |
5,771 |
Human adenoidal organ culture: A model to study nontypable haemophilus influenzae (NTHI) and other bacterial interactions with nasopharyngeal mucosa—implications in otitis media : Bernstein J.M.; Hard R.; Cui Z.D.; Nobuo S.; Fisher J.; Ogra P.L.OTolaryngol. Head Neck Surg. (1990) 103/5 I (784–791)
| null |
5,772 |
T-lymphocyte subset abnormalities in the Guillain-Barré syndrome
| null |
5,773 |
Cumulative Contents, volumes 123-130
| null |
5,774 |
Antigen presentation by human autoreactive PLP specific T-cell clones
| null |
5,775 |
AAVI/ACVM Symposium—Mucosal Infection and Immunity: Sunday November 13, 1994 (1 p.m. to 5 p.m.) Gold Room, Ramanda Congress Hotel Chicago, IL, USA
| null |
5,776 |
Cytokines
| null |
5,777 |
Phenotypic and functional properties of CD8(+) T-lymphocytes from the CNS of rats with coronavirus-induced encephalomyelitis
| null |
5,778 |
Author index (vol. 12)
| null |
5,779 |
Mucosal immunity
| null |
5,780 |
Corrigendum to “Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital” [J. Virol. Methods 128 (2005) 156–161]
| null |
5,781 |
Microglia reaction on the neurotoxic effect of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) in the nigrostriatal pathway in mice
| null |
5,782 |
Alterations of macrophage functions during acute murine cytomegalovirus infection
| null |
5,783 |
Neutrophil induced T-cell apoptosis during a viral infection
| null |
5,784 |
Subject index : Veterinary Immunology and Immunopathology, volumes 26–50, 1990–1996
| null |
5,785 |
Astrocyte-derived TGF β is secreted during persistent coronovirus infection
| null |
5,786 |
Immunology of viral infection
| null |
5,787 |
Interleukin-4 enhances in vitro T-cell recruitment in glioblastoma-bearing patients
| null |
5,788 |
IL-2 and IL-4 gene expression in human peripheral blood and intestinal biopsies
| null |
5,789 |
Volume 127 - Contents
| null |
5,790 |
Virus-induced type-1 cytokine response in IL-12 deficient mice
| null |
5,791 |
Influence of MHC class I and class II (mis)matching between donor and recipient on the cytomegalovirus induced accelerated graft arterioscierosis in a rat aorta transplant model
| null |
5,792 |
Lymphoid architecture and distribution of HIV-1 in chronic HIV-1 infected chimpanzees
| null |
5,793 |
Mitogenetic effect of saliva to peripheral lymphocytes in patients with oral cancer and chronic nasopharyngeal infections
| null |
5,794 |
CTLA4-Ig treatment prevents murine experimental autoimmune encephalomyelitis
| null |
5,795 |
Cytokine gene expression in mucosal T lymphocyte populations
| null |
5,796 |
A functional interleukin-1 type 1 receptor on rat brain endothelial cells
| null |
5,797 |
Attenuated recombinant Bordetella pertussis as live vaccines for the protection against homologous and heterologous diseases
| null |
5,798 |
TGEV-specific IgA at different mucosae following infection of pigs with transmissible gastroenteritis virus or the antigenically related porcine respiratory coronavirus()
| null |
5,799 |
The signal sequence of lymphocytic choriomeningitis virus contains an immuno-dominant CD8(+) cytotoxic T cell epitope that is restricted by both H-2D(b) and H-2K(b) molecules
| null |
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