bio-datasets/bigbio-ner-merged · Datasets at Hugging Face

answer stringlengths 1 16.1k	id stringlengths 7 56	instruction stringlengths 106 72.6k	ner_tags list	text stringlengths 5 72.4k	tokens list	types list
ghrelin is a protein, serine is a compound	DS.d1801_task1	Sentence: The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size. Instructions: please typing these entity words according to sentence: ghrelin, serine Options: compound, protein	[ "O", "O", "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size.	[ "The", "acyl", "ghrelin", "peptide", "features", "a", "unique", "post", "-", "translational", "modification", "of", "O", "-", "n", "-", "octanoylation", "at", "serine", "3", ",", "and", "is", "the", "only", "gastrointestinal", "signal", "that", "increases", "meal", "size", "." ]	[ "protein", "compound" ]
ghrelin, serine	DS.d1801_task2	Sentence: The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size. Instructions: please extract entity words from the input sentence	[ "O", "O", "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size.	[ "The", "acyl", "ghrelin", "peptide", "features", "a", "unique", "post", "-", "translational", "modification", "of", "O", "-", "n", "-", "octanoylation", "at", "serine", "3", ",", "and", "is", "the", "only", "gastrointestinal", "signal", "that", "increases", "meal", "size", "." ]	[ "protein", "compound" ]
tissue specimens is a Tissue, fragment is a Cancer, tumour is a Cancer, endometrial biopsy is a Tissue, fragment is a Cancer, tissue fragments is a Tissue, specimens is a Tissue	PMID-10823148_task0	Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Tissue, Cancer	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]	Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.	[ "Application", "of", "microsatellite", "PCR", "techniques", "in", "the", "identification", "of", "mixed", "up", "tissue", "specimens", "in", "surgical", "pathology", ".", "\n", "A", "fragment", "of", "tumour", "was", "erroneously", "mixed", "up", "with", "an", "endometrial", "biopsy", ".", "Micro", "-", "satellite", "polymerase", "chain", "reaction", "(", "PCR", ")", "clearly", "demonstrated", "the", "extraneous", "nature", "of", "the", "fragment", ".", "Micro", "-", "satellite", "PCR", "may", "be", "useful", "for", "the", "identification", "of", "mis", "-", "labelled", "or", "mismatched", "tissue", "fragments", "in", "surgical", "pathology", "specimens", ".", "\n" ]	[ "Tissue", "Cancer" ]
tissue specimens is a Tissue, fragment is a Cancer, tumour is a Cancer, endometrial biopsy is a Tissue, fragment is a Cancer, tissue fragments is a Tissue, specimens is a Tissue	PMID-10823148_task1	Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please typing these entity words according to sentence: tissue specimens, fragment, tumour, endometrial biopsy, fragment, tissue fragments, specimens Options: Tissue, Cancer	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]	Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.	[ "Application", "of", "microsatellite", "PCR", "techniques", "in", "the", "identification", "of", "mixed", "up", "tissue", "specimens", "in", "surgical", "pathology", ".", "\n", "A", "fragment", "of", "tumour", "was", "erroneously", "mixed", "up", "with", "an", "endometrial", "biopsy", ".", "Micro", "-", "satellite", "polymerase", "chain", "reaction", "(", "PCR", ")", "clearly", "demonstrated", "the", "extraneous", "nature", "of", "the", "fragment", ".", "Micro", "-", "satellite", "PCR", "may", "be", "useful", "for", "the", "identification", "of", "mis", "-", "labelled", "or", "mismatched", "tissue", "fragments", "in", "surgical", "pathology", "specimens", ".", "\n" ]	[ "Tissue", "Cancer" ]
tissue specimens, fragment, tumour, endometrial biopsy, fragment, tissue fragments, specimens	PMID-10823148_task2	Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]	Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.	[ "Application", "of", "microsatellite", "PCR", "techniques", "in", "the", "identification", "of", "mixed", "up", "tissue", "specimens", "in", "surgical", "pathology", ".", "\n", "A", "fragment", "of", "tumour", "was", "erroneously", "mixed", "up", "with", "an", "endometrial", "biopsy", ".", "Micro", "-", "satellite", "polymerase", "chain", "reaction", "(", "PCR", ")", "clearly", "demonstrated", "the", "extraneous", "nature", "of", "the", "fragment", ".", "Micro", "-", "satellite", "PCR", "may", "be", "useful", "for", "the", "identification", "of", "mis", "-", "labelled", "or", "mismatched", "tissue", "fragments", "in", "surgical", "pathology", "specimens", ".", "\n" ]	[ "Tissue", "Cancer" ]
Fc gamma RI is a Protein, Fc gamma RII is a Protein, TNF - alpha is a Protein, IL-1 beta is a Protein, TNF - alpha is a Protein	558_task0	Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Protein	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.	[ "Cross", "-", "linking", "of", "Fc", "gamma", "receptors", "activates", "HIV-1", "long", "terminal", "repeat", "-", "driven", "transcription", "in", "human", "monocytes", ".", "\n", "Elevation", "of", "the", "levels", "of", "circulating", "immune", "complexes", "frequently", "accompanies", "HIV-1", "infection", "and", "is", "a", "prognostic", "indicator", "of", "clinical", "progression", "from", "asymptomatic", "infection", "to", "AIDS", ".", "Here", "we", "report", "that", "cross", "-", "linking", "of", "Fc", "gamma", "RI", "or", "Fc", "gamma", "RII", "by", "adherent", "human", "IgG", "or", "by", "specific", "anti", "-", "Fc", "gamma", "R", "mAb", "activates", "HIV-1", "gene", "expression", "in", "the", "human", "monocytic", "cell", "line", "BF24", "and", "increased", "HIV", "RNA", "expression", "in", "monocytes", "from", "HIV", "infected", "patients", "as", "assayed", "by", "reverse", "transcription", "-", "PCR", ".", "In", "THP-1", "cells", ",", "Fc", "gamma", "R", "cross", "-", "linking", "induced", "NF", "-", "kappa", "B", ",", "which", "is", "known", "to", "bind", "to", "the", "regulatory", "region", "of", "the", "long", "terminal", "repeat", "(", "LTR", ")", "of", "HIV-1", "and", "to", "activate", "HIV-1", "transcription", ".", "Anti", "-", "TNF", "-", "alpha", "antibody", "but", "not", "anti", "-", "IL-1", "beta", "antibody", "strongly", "inhibited", "both", "the", "induction", "of", "HIV-1-LTR", "-", "driven", "transcription", "and", "the", "induction", "of", "NF", "-", "kappa", "B", "by", "Fc", "gamma", "R", "cross", "-", "linking", ".", "These", "results", "indicate", "that", "Fc", "gamma", "R", "can", "mediate", "a", "TNF", "-", "alpha", "-", "dependent", "induction", "of", "HIV-1", "gene", "transcription", "and", "suggest", "that", "immune", "complexes", "may", "contribute", "to", "the", "pathophysiology", "of", "HIV-1", "infection", "by", "augmenting", "viral", "replication", "in", "monocytes", "." ]	[ "Protein" ]
Fc gamma RI is a Protein, Fc gamma RII is a Protein, TNF - alpha is a Protein, IL-1 beta is a Protein, TNF - alpha is a Protein	558_task1	Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please typing these entity words according to sentence: Fc gamma RI, Fc gamma RII, TNF - alpha, IL-1 beta, TNF - alpha Options: Protein	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.	[ "Cross", "-", "linking", "of", "Fc", "gamma", "receptors", "activates", "HIV-1", "long", "terminal", "repeat", "-", "driven", "transcription", "in", "human", "monocytes", ".", "\n", "Elevation", "of", "the", "levels", "of", "circulating", "immune", "complexes", "frequently", "accompanies", "HIV-1", "infection", "and", "is", "a", "prognostic", "indicator", "of", "clinical", "progression", "from", "asymptomatic", "infection", "to", "AIDS", ".", "Here", "we", "report", "that", "cross", "-", "linking", "of", "Fc", "gamma", "RI", "or", "Fc", "gamma", "RII", "by", "adherent", "human", "IgG", "or", "by", "specific", "anti", "-", "Fc", "gamma", "R", "mAb", "activates", "HIV-1", "gene", "expression", "in", "the", "human", "monocytic", "cell", "line", "BF24", "and", "increased", "HIV", "RNA", "expression", "in", "monocytes", "from", "HIV", "infected", "patients", "as", "assayed", "by", "reverse", "transcription", "-", "PCR", ".", "In", "THP-1", "cells", ",", "Fc", "gamma", "R", "cross", "-", "linking", "induced", "NF", "-", "kappa", "B", ",", "which", "is", "known", "to", "bind", "to", "the", "regulatory", "region", "of", "the", "long", "terminal", "repeat", "(", "LTR", ")", "of", "HIV-1", "and", "to", "activate", "HIV-1", "transcription", ".", "Anti", "-", "TNF", "-", "alpha", "antibody", "but", "not", "anti", "-", "IL-1", "beta", "antibody", "strongly", "inhibited", "both", "the", "induction", "of", "HIV-1-LTR", "-", "driven", "transcription", "and", "the", "induction", "of", "NF", "-", "kappa", "B", "by", "Fc", "gamma", "R", "cross", "-", "linking", ".", "These", "results", "indicate", "that", "Fc", "gamma", "R", "can", "mediate", "a", "TNF", "-", "alpha", "-", "dependent", "induction", "of", "HIV-1", "gene", "transcription", "and", "suggest", "that", "immune", "complexes", "may", "contribute", "to", "the", "pathophysiology", "of", "HIV-1", "infection", "by", "augmenting", "viral", "replication", "in", "monocytes", "." ]	[ "Protein" ]
Fc gamma RI, Fc gamma RII, TNF - alpha, IL-1 beta, TNF - alpha	558_task2	Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Protein", "I-Protein", "I-Protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.	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syndromes is an umlsterm, PNS is an umlsterm, disorders is an umlsterm, nervous system is an umlsterm, tumor is an umlsterm, treatment is an umlsterm, PNS is an umlsterm, association is an umlsterm, lung is an umlsterm, breast is an umlsterm, carcinomas is an umlsterm, PNS is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, time is an umlsterm, value is an umlsterm, carcinoma is an umlsterm, PNS is an umlsterm, anatomical is an umlsterm, antibodies is an umlsterm, syndromes is an umlsterm, encephalitis is an umlsterm, Opsoclonus - Myoclonus syndrome is an umlsterm, Stiff - man syndrome is an umlsterm, neuromyotonia is an umlsterm, amaurosis is an umlsterm, autoantibodies is an umlsterm, neoplasm is an umlsterm, autoantibodies is an umlsterm, antibodies is an umlsterm, calcium channels is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, potassium channels is an umlsterm, neuromyotonia is an umlsterm, recoverin is an umlsterm, cancer is an umlsterm, retinopathy is an umlsterm, symptoms is an umlsterm, PNS is an umlsterm, tumors is an umlsterm, antibodies is an umlsterm, diagnosis is an umlsterm, pathogenesis is an umlsterm, PNS is an umlsterm	DerNervenarzt.90700688.eng.abstr_task0	Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .	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syndromes is an umlsterm, PNS is an umlsterm, disorders is an umlsterm, nervous system is an umlsterm, tumor is an umlsterm, treatment is an umlsterm, PNS is an umlsterm, association is an umlsterm, lung is an umlsterm, breast is an umlsterm, carcinomas is an umlsterm, PNS is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, time is an umlsterm, value is an umlsterm, carcinoma is an umlsterm, PNS is an umlsterm, anatomical is an umlsterm, antibodies is an umlsterm, syndromes is an umlsterm, encephalitis is an umlsterm, Opsoclonus - Myoclonus syndrome is an umlsterm, Stiff - man syndrome is an umlsterm, neuromyotonia is an umlsterm, amaurosis is an umlsterm, autoantibodies is an umlsterm, neoplasm is an umlsterm, autoantibodies is an umlsterm, antibodies is an umlsterm, calcium channels is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, potassium channels is an umlsterm, neuromyotonia is an umlsterm, recoverin is an umlsterm, cancer is an umlsterm, retinopathy is an umlsterm, symptoms is an umlsterm, PNS is an umlsterm, tumors is an umlsterm, antibodies is an umlsterm, diagnosis is an umlsterm, pathogenesis is an umlsterm, PNS is an umlsterm	DerNervenarzt.90700688.eng.abstr_task1	Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please typing these entity words according to sentence: syndromes, PNS, disorders, nervous system, tumor, treatment, PNS, association, lung, breast, carcinomas, PNS, Lambert - Eaton myasthenic syndrome, time, value, carcinoma, PNS, anatomical, antibodies, syndromes, encephalitis, Opsoclonus - Myoclonus syndrome, Stiff - man syndrome, neuromyotonia, amaurosis, autoantibodies, neoplasm, autoantibodies, antibodies, calcium channels, Lambert - Eaton myasthenic syndrome, potassium channels, neuromyotonia, recoverin, cancer, retinopathy, symptoms, PNS, tumors, antibodies, diagnosis, pathogenesis, PNS Options: umlsterm	[ "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .	[ "Paraneoplastic", "neurologic", "syndromes", "(", "PNS", ")", "are", "rare", "disorders", "of", "the", "nervous", "system", "that", "cannot", "be", "ascribed", "to", "metatastases", "or", "to", "destruction", "of", "vital", "systemic", "organs", "by", "the", "tumor", "or", "its", "treatment", ".", "Most", "frequently", ",", "PNS", "occur", "in", "association", "with", "small", "-", "cell", "lung", ",", "breast", "or", "ovarian", "carcinomas", ".", "The", "most", "frequent", "PNS", "is", "Lambert", "-", "Eaton", "myasthenic", "syndrome", ",", "which", "at", "the", "same", "time", "has", "the", "highest", "predictive", "value", "concerning", "an", "underlying", "carcinoma", ".", "PNS", "have", "been", "classified", "mostly", "under", "anatomical", "aspects", "but", "now", "are", "increasingly", "categorized", "according", "to", "specific", "antibodies", ".", "In", "certain", "neurologic", "syndromes", "(", "sensible", "and", "autonomic", "neuropathy", ",", "cerebellitis", ",", "limbic", "encephalitis", ",", "Opsoclonus", "-", "Myoclonus", "syndrome", ",", "Stiff", "-", "man", "syndrome", ",", "neuromyotonia", ",", "subacute", "amaurosis", ")", "specific", "autoantibodies", "are", "highly", "predictive", "for", "a", "neoplasm", ".", "Pathogenic", "relevance", "of", "these", "autoantibodies", "has", "been", "demonstrated", "only", "for", "antibodies", "against", "(", "1", ")", "voltage", "gated", "calcium", "channels", "(", "VGCC", ")", "in", "Lambert", "-", "Eaton", "myasthenic", "syndrome", ",", "(", "2", ")", "voltage", "gated", "potassium", "channels", "(", "VGKC", ")", "in", "neuromyotonia", ",", "and", "(", "3", ")", "recoverin", "in", "cancer", "associated", "retinopathy", ".", "The", "present", "article", "deals", "with", "the", "neurological", "symptoms", "of", "PNS", ",", "associated", "tumors", ",", "and", "the", "relevance", "of", "specific", "antibodies", "for", "the", "diagnosis", "and", "pathogenesis", "of", "PNS", "." ]	[ "umlsterm" ]
syndromes, PNS, disorders, nervous system, tumor, treatment, PNS, association, lung, breast, carcinomas, PNS, Lambert - Eaton myasthenic syndrome, time, value, carcinoma, PNS, anatomical, antibodies, syndromes, encephalitis, Opsoclonus - Myoclonus syndrome, Stiff - man syndrome, neuromyotonia, amaurosis, autoantibodies, neoplasm, autoantibodies, antibodies, calcium channels, Lambert - Eaton myasthenic syndrome, potassium channels, neuromyotonia, recoverin, cancer, retinopathy, symptoms, PNS, tumors, antibodies, diagnosis, pathogenesis, PNS	DerNervenarzt.90700688.eng.abstr_task2	Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please extract entity words from the input sentence	[ "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .	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Abstract is an umlsterm, incidence is an umlsterm, malignant neoplasms is an umlsterm, pleura is an umlsterm, pericardium is an umlsterm, peritoneum is an umlsterm, Germany is an umlsterm, asbestos is an umlsterm, Germany is an umlsterm, mesotheliomas is an umlsterm, Mesothelioma is an umlsterm, Registry is an umlsterm, asbestos is an umlsterm, occupational exposure is an umlsterm, associations is an umlsterm, mesotheliomas is an umlsterm, Mesothelioma is an umlsterm, Registry is an umlsterm, mesotheliomas is an umlsterm, etiology is an umlsterm, pathogenesis is an umlsterm, diagnostic is an umlsterm, procedures is an umlsterm, standards is an umlsterm, genetic defects is an umlsterm, mesothelioma is an umlsterm, malignant is an umlsterm, mesotheliomas is an umlsterm, genetic alterations is an umlsterm, diagnosis is an umlsterm, therapeutic is an umlsterm, biopsy is an umlsterm, Surgery is an umlsterm, role is an umlsterm, therapy is an umlsterm, malignant tumors is an umlsterm, membranes is an umlsterm, diagnosis is an umlsterm, tumor is an umlsterm, stages is an umlsterm	DerChirurg.00710877.eng.abstr_task0	Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O" ]	Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .	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Abstract is an umlsterm, incidence is an umlsterm, malignant neoplasms is an umlsterm, pleura is an umlsterm, pericardium is an umlsterm, peritoneum is an umlsterm, Germany is an umlsterm, asbestos is an umlsterm, Germany is an umlsterm, mesotheliomas is an umlsterm, Mesothelioma is an umlsterm, Registry is an umlsterm, asbestos is an umlsterm, occupational exposure is an umlsterm, associations is an umlsterm, mesotheliomas is an umlsterm, Mesothelioma is an umlsterm, Registry is an umlsterm, mesotheliomas is an umlsterm, etiology is an umlsterm, pathogenesis is an umlsterm, diagnostic is an umlsterm, procedures is an umlsterm, standards is an umlsterm, genetic defects is an umlsterm, mesothelioma is an umlsterm, malignant is an umlsterm, mesotheliomas is an umlsterm, genetic alterations is an umlsterm, diagnosis is an umlsterm, therapeutic is an umlsterm, biopsy is an umlsterm, Surgery is an umlsterm, role is an umlsterm, therapy is an umlsterm, malignant tumors is an umlsterm, membranes is an umlsterm, diagnosis is an umlsterm, tumor is an umlsterm, stages is an umlsterm	DerChirurg.00710877.eng.abstr_task1	Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please typing these entity words according to sentence: Abstract, incidence, malignant neoplasms, pleura, pericardium, peritoneum, Germany, asbestos, Germany, mesotheliomas, Mesothelioma, Registry, asbestos, occupational exposure, associations, mesotheliomas, Mesothelioma, Registry, mesotheliomas, etiology, pathogenesis, diagnostic, procedures, standards, genetic defects, mesothelioma, malignant, mesotheliomas, genetic alterations, diagnosis, therapeutic, biopsy, Surgery, role, therapy, malignant tumors, membranes, diagnosis, tumor, stages Options: umlsterm	[ "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O" ]	Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .	[ "Abstract", ".", "The", "incidence", "of", "primary", "malignant", "neoplasms", "of", "the", "pleura", ",", "the", "pericardium", "and", "the", "peritoneum", "in", "Germany", "has", "been", "rising", "since", "about", "the", "mid-1980", "s.", "A", "continuing", "rise", "is", "expected", "until", "about", "2020", ",", "predominantly", "due", "to", "the", "peak", "of", "asbestos", "processing", "in", "Germany", "between", "1965", "and", "1980", ".", "About", "90", "%", "of", "the", "mesotheliomas", "stored", "in", "the", "files", "of", "the", "German", "Mesothelioma", "Registry", "in", "Bochum", "are", "asbestos", "related", "and", "therefore", "possibly", "due", "to", "occupational", "exposure", "that", "may", "be", "compensated", "by", "the", "professional", "associations", ".", "More", "than", "500", "mesotheliomas", "annually", "can", "be", "diagnosed", "in", "the", "German", "Mesothelioma", "Registry", ".", "In", "this", "first", "part", "of", "the", "series", "on", "mesotheliomas", ",", "current", "concepts", "on", "etiology", "and", "pathogenesis", "as", "well", "as", "diagnostic", "procedures", "and", "standards", "are", "discussed", ".", "At", "the", "present", ",", "specific", "chromosomal", "or", "genetic", "defects", "that", "constantly", "give", "rise", "to", "a", "mesothelioma", "are", "not", "known", ".", "The", "initiation", "and", "progression", "of", "malignant", "mesotheliomas", "is", "a", "highly", "complex", "mechanism", "that", "is", "based", "on", "individual", "genetic", "alterations", ".", "A", "reliable", "diagnosis", "is", "the", "basis", "for", "therapeutic", ",", "prognostic", "and", "medicolegal", "conseques", ";", "in", "general", ",", "it", "can", "be", "achieved", "by", "thoracoscopic", "inspection", "with", "selected", "biopsy", ".", "Surgery", "may", "gain", "a", "more", "important", "role", "in", "the", "therapy", "of", "malignant", "tumors", "of", "serosal", "membranes", "not", "only", "in", "palliative", ",", "but", "also", "in", "potential", "curative", "approaches", "if", "the", "diagnosis", "can", "be", "made", "at", "earlier", "tumor", "stages", "." ]	[ "umlsterm" ]
Abstract, incidence, malignant neoplasms, pleura, pericardium, peritoneum, Germany, asbestos, Germany, mesotheliomas, Mesothelioma, Registry, asbestos, occupational exposure, associations, mesotheliomas, Mesothelioma, Registry, mesotheliomas, etiology, pathogenesis, diagnostic, procedures, standards, genetic defects, mesothelioma, malignant, mesotheliomas, genetic alterations, diagnosis, therapeutic, biopsy, Surgery, role, therapy, malignant tumors, membranes, diagnosis, tumor, stages	DerChirurg.00710877.eng.abstr_task2	Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please extract entity words from the input sentence	[ "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O" ]	Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .	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5-(hydroxy)methylcytosine is a CHEMICAL	23434322_task0	Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: CHEMICAL	[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]	Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.	[ "Dynamic", "readers", "for", "5-(hydroxy)methylcytosine", "and", "its", "oxidized", "derivatives", "." ]	[ "CHEMICAL", "GENE-Y" ]
5-(hydroxy)methylcytosine is a CHEMICAL	23434322_task1	Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please typing these entity words according to sentence: 5-(hydroxy)methylcytosine Options: CHEMICAL	[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]	Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.	[ "Dynamic", "readers", "for", "5-(hydroxy)methylcytosine", "and", "its", "oxidized", "derivatives", "." ]	[ "CHEMICAL", "GENE-Y" ]
5-(hydroxy)methylcytosine	23434322_task2	Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]	Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.	[ "Dynamic", "readers", "for", "5-(hydroxy)methylcytosine", "and", "its", "oxidized", "derivatives", "." ]	[ "CHEMICAL", "GENE-Y" ]
Fruchtwasser is an umlsterm, Lebens- is an umlsterm, Morbiditaet is an umlsterm, Mortalitaet is an umlsterm, Schwangerschaften is an umlsterm, Therapie is an umlsterm, Behandlung is an umlsterm, Amniondrainage is an umlsterm, Indometacin is an umlsterm, Sulindac is an umlsterm, Urinproduktion is an umlsterm, Druckes is an umlsterm, Amniondrainage is an umlsterm, Fruchtwasservermehrung is an umlsterm, Therapie is an umlsterm, Therapie is an umlsterm, Fruchtwasservermehrung is an umlsterm, Komplikationen is an umlsterm	DerGynaekologe.90320823.ger.abstr_task0	Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . "	[ "Fruchtwasser", "ist", "ein", "essentieller", "Lebens-", "und", "Entwicklungsfaktor", "in", "utero", ".", "Bei", "Abweichungen", "vom", "Normvolumen", "ist", "mit", "einer", "erhoehten", "perinatalen", "Morbiditaet", "und", "Mortalitaet", "zu", "rechnen", ";", "0,2", "-", "1,6", "%", "der", "Schwangerschaften", "sind", "mit", "einer", "vermehrten", "Fruchtwassermenge", "belastet", ".", "Die", "haeufigste", "Indikation", "zur", "Therapie", "ist", "ein", "fetofetales", "Transfusionssyndrom", "bei", "monochorialen", "Mehrlingen", ".", "Die", "Behandlung", "des", "Polyhydramnions", "basiert", "auf", "der", "Beseitigung", "der", "ursaechlichen", "Stoerung", "oder", "der", "symptomatischen", "Korrektur", "durch", "Amniondrainage", ".", "Die", "medikamentoese", "Reduktion", "des", "polyurischen", "Polyhydramnions", "ist", "durch", "Zyklooxygenasehemmer", "moeglich", ".", "Indometacin", "Sulindac", "oder", "Nimesulide", ",", "fuehren", "ueber", "die", "Drosselung", "der", "kindlichen", "Urinproduktion", "zum", "Behandlungserfolg", ".", "Rasche", "Entlastung", "des", "erhoehten", "intrauterinen", "Druckes", "eroeffnet", "die", "grossvolumige", "Amniondrainage", ".", "Bei", "weitem", "nicht", "jede", "Fruchtwasservermehrung", "bedarf", "der", "Therapie", ".", "Milde", "Formen", "profitieren", "von", "expektativem", "Vorgehen", ".", "Der", "grundsaetzliche", "Ansatz", "der", "direkten", "oder", "indirekten", "Therapie", "einer", "Fruchtwasservermehrung", "zielt", "somit", "nicht", "auf", "die", "Korrektur", "des", "Polyhydramnions", "an", "sich", ",", "sondern", "vielmehr", "auf", "die", "Praevention", "seiner", "Komplikationen", ".", "Die", "Tragzeitverlaengerung", "und", "/", "oder", "die", "Verringerung", "der", "maternalen", "Verdraengungssymptome", "verbessern", "den", "fetal", "outcome", "\"", ".", "\"" ]	[ "umlsterm" ]
Fruchtwasser is an umlsterm, Lebens- is an umlsterm, Morbiditaet is an umlsterm, Mortalitaet is an umlsterm, Schwangerschaften is an umlsterm, Therapie is an umlsterm, Behandlung is an umlsterm, Amniondrainage is an umlsterm, Indometacin is an umlsterm, Sulindac is an umlsterm, Urinproduktion is an umlsterm, Druckes is an umlsterm, Amniondrainage is an umlsterm, Fruchtwasservermehrung is an umlsterm, Therapie is an umlsterm, Therapie is an umlsterm, Fruchtwasservermehrung is an umlsterm, Komplikationen is an umlsterm	DerGynaekologe.90320823.ger.abstr_task1	Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please typing these entity words according to sentence: Fruchtwasser, Lebens-, Morbiditaet, Mortalitaet, Schwangerschaften, Therapie, Behandlung, Amniondrainage, Indometacin, Sulindac, Urinproduktion, Druckes, Amniondrainage, Fruchtwasservermehrung, Therapie, Therapie, Fruchtwasservermehrung, Komplikationen Options: umlsterm	[ "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . "	[ "Fruchtwasser", "ist", "ein", "essentieller", "Lebens-", "und", "Entwicklungsfaktor", "in", "utero", ".", "Bei", "Abweichungen", "vom", "Normvolumen", "ist", "mit", "einer", "erhoehten", "perinatalen", "Morbiditaet", "und", "Mortalitaet", "zu", "rechnen", ";", "0,2", "-", "1,6", "%", "der", "Schwangerschaften", "sind", "mit", "einer", "vermehrten", "Fruchtwassermenge", "belastet", ".", "Die", "haeufigste", "Indikation", "zur", "Therapie", "ist", "ein", "fetofetales", "Transfusionssyndrom", "bei", "monochorialen", "Mehrlingen", ".", "Die", "Behandlung", "des", "Polyhydramnions", "basiert", "auf", "der", "Beseitigung", "der", "ursaechlichen", "Stoerung", "oder", "der", "symptomatischen", "Korrektur", "durch", "Amniondrainage", ".", "Die", "medikamentoese", "Reduktion", "des", "polyurischen", "Polyhydramnions", "ist", "durch", "Zyklooxygenasehemmer", "moeglich", ".", "Indometacin", "Sulindac", "oder", "Nimesulide", ",", "fuehren", "ueber", "die", "Drosselung", "der", "kindlichen", "Urinproduktion", "zum", "Behandlungserfolg", ".", "Rasche", "Entlastung", "des", "erhoehten", "intrauterinen", "Druckes", "eroeffnet", "die", "grossvolumige", "Amniondrainage", ".", "Bei", "weitem", "nicht", "jede", "Fruchtwasservermehrung", "bedarf", "der", "Therapie", ".", "Milde", "Formen", "profitieren", "von", "expektativem", "Vorgehen", ".", "Der", "grundsaetzliche", "Ansatz", "der", "direkten", "oder", "indirekten", "Therapie", "einer", "Fruchtwasservermehrung", "zielt", "somit", "nicht", "auf", "die", "Korrektur", "des", "Polyhydramnions", "an", "sich", ",", "sondern", "vielmehr", "auf", "die", "Praevention", "seiner", "Komplikationen", ".", "Die", "Tragzeitverlaengerung", "und", "/", "oder", "die", "Verringerung", "der", "maternalen", "Verdraengungssymptome", "verbessern", "den", "fetal", "outcome", "\"", ".", "\"" ]	[ "umlsterm" ]
Fruchtwasser, Lebens-, Morbiditaet, Mortalitaet, Schwangerschaften, Therapie, Behandlung, Amniondrainage, Indometacin, Sulindac, Urinproduktion, Druckes, Amniondrainage, Fruchtwasservermehrung, Therapie, Therapie, Fruchtwasservermehrung, Komplikationen	DerGynaekologe.90320823.ger.abstr_task2	Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please extract entity words from the input sentence	[ "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . 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retrospective study is an umlsterm, medical records is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, antibiotic prophylaxis is an umlsterm, risk of is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, injuries is an umlsterm, occurrence is an umlsterm, meningitis is an umlsterm, use is an umlsterm, antibiotic is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, findings is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, prophylactic is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, antibiotic is an umlsterm, therapy is an umlsterm, symptoms is an umlsterm, meningitis is an umlsterm	HNO.70450448.eng.abstr_task0	Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .	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retrospective study is an umlsterm, medical records is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, antibiotic prophylaxis is an umlsterm, risk of is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, injuries is an umlsterm, occurrence is an umlsterm, meningitis is an umlsterm, use is an umlsterm, antibiotic is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, findings is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, prophylactic is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, antibiotic is an umlsterm, therapy is an umlsterm, symptoms is an umlsterm, meningitis is an umlsterm	HNO.70450448.eng.abstr_task1	Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please typing these entity words according to sentence: retrospective study, medical records, patients, skull base, fractures, antibiotic prophylaxis, risk of, meningitis, patients, antibiotics, meningitis, patients, antibiotics, meningitis, skull base, fractures, injuries, occurrence, meningitis, use, antibiotic, patients, antibiotics, patients, meningitis, patients, antibiotics, meningitis, findings, patients, skull base, fractures, prophylactic, antibiotics, patients, antibiotic, therapy, symptoms, meningitis Options: umlsterm	[ "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .	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retrospective study, medical records, patients, skull base, fractures, antibiotic prophylaxis, risk of, meningitis, patients, antibiotics, meningitis, patients, antibiotics, meningitis, skull base, fractures, injuries, occurrence, meningitis, use, antibiotic, patients, antibiotics, patients, meningitis, patients, antibiotics, meningitis, findings, patients, skull base, fractures, prophylactic, antibiotics, patients, antibiotic, therapy, symptoms, meningitis	HNO.70450448.eng.abstr_task2	Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please extract entity words from the input sentence	[ "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O" ]	A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .	[ "A", "retrospective", "study", "over", "5", "years", "evaluated", "the", "medical", "records", "of", "78", "patients", "who", "had", "suffered", "lateral", "skull", "base", "fractures", ".", "The", "purpose", "of", "the", "present", "study", "was", "to", "answer", "the", "question", "of", "whether", "antibiotic", "prophylaxis", "reduced", "the", "risk", "of", "meningitis", ".", "Fifty", "-", "five", "of", "78", "patients", "(", "71", "%", ")", "were", "given", "no", "antibiotics", ",", "among", "whom", "four", "developed", "meningitis", ".", "In", "29", "%", "of", "patients", "treated", "with", "antibiotics", ",", "two", "developed", "meningitis", ".", "This", "difference", "was", "not", "significant", ".", "Even", "when", "cases", "with", "uncomplicated", "(", "\"", "simple", "\"", ")", "lateral", "skull", "base", "fractures", "were", "separated", "from", "those", "with", "severe", "additional", "lesions", "related", "to", "their", "injuries", ",", "no", "significant", "correlation", "was", "found", "in", "the", "occurrence", "of", "meningitis", "despite", "the", "use", "of", "an", "antibiotic", ".", "Eight", "of", "14", "patients", "with", "initial", "otoliquorrheas", "were", "treated", "with", "antibiotics", ",", "with", "two", "of", "these", "8", "patients", "developing", "meningitis", ".", "None", "of", "the", "patients", "who", "did", "not", "receive", "antibiotics", "developed", "meningitis", ".", "Our", "findings", "show", "that", "it", "is", "not", "advisible", "to", "treat", "patients", "who", "have", "suffered", "from", "lateral", "skull", "base", "fractures", "with", "prophylactic", "antibiotics", ".", "Instead", ",", "these", "patients", "should", "be", "examined", "frequently", "and", "appropriate", "antibiotic", "therapy", "prescribed", "at", "the", "first", "clinical", "symptoms", "of", "meningitis", "." ]	[ "umlsterm" ]
protein kinase C inhibitors is an other_name, fibronectin is a protein_molecule, interleukin - beta gene is a DNA_domain_or_region, human monocytic cells is a cell_type	69896_task0	Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: cell_type, DNA_domain_or_region, protein_molecule, other_name	[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]	Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.	[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]	[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]
protein kinase C inhibitors is an other_name, fibronectin is a protein_molecule, interleukin - beta gene is a DNA_domain_or_region, human monocytic cells is a cell_type	69896_task1	Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please typing these entity words according to sentence: protein kinase C inhibitors, fibronectin, interleukin - beta gene, human monocytic cells Options: cell_type, DNA_domain_or_region, protein_molecule, other_name	[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]	Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.	[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]	[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]
protein kinase C inhibitors, fibronectin, interleukin - beta gene, human monocytic cells	69896_task2	Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]	Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.	[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]	[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]
Brain activity correlates is a Participant_Condition, synchronisation is a Intervention_Physical, continuation is a Intervention_Physical, paced finger tapping is a Intervention_Physical, Activity in parts of the human motor system is a Outcome_Physical, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) is a Intervention_Physical, continued tapping in absence of the auditory pacer is a Intervention_Physical, activation of bilateral SMA and basal ganglia is a Outcome_Physical	17402_task0	Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Physical, Outcome_Physical, Participant_Condition	[ "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .	[ "Brain", "activity", "correlates", "differentially", "with", "increasing", "temporal", "complexity", "of", "rhythms", "during", "initialisation", ",", "synchronisation", ",", "and", "continuation", "phases", "of", "paced", "finger", "tapping", ".", "Activity", "in", "parts", "of", "the", "human", "motor", "system", "has", "been", "shown", "to", "correlate", "with", "the", "complexity", "of", "performed", "motor", "sequences", "in", "terms", "of", "the", "number", "of", "limbs", "moved", ",", "number", "of", "movements", ",", "and", "number", "of", "trajectories", ".", "Here", ",", "we", "searched", "for", "activity", "correlating", "with", "temporal", "complexity", ",", "in", "terms", "of", "the", "number", "of", "different", "intervals", "produced", "in", "the", "sequence", ",", "using", "an", "overlearned", "tapping", "task", ".", "Our", "task", "was", "divided", "into", "three", "phases", ":", "movement", "selection", "and", "initiation", "(", "initiate", ")", ",", "synchronisation", "of", "finger", "tapping", "with", "an", "external", "auditory", "cue", "(", "synchronise", ")", ",", "and", "continued", "tapping", "in", "absence", "of", "the", "auditory", "pacer", "(", "continue", ")", ".", "Comparisons", "between", "synchronisation", "and", "continuation", "showed", "a", "pattern", "in", "keeping", "with", "prior", "neuroimaging", "studies", "of", "paced", "finger", "tapping", ".", "Thus", ",", "activation", "of", "bilateral", "SMA", "and", "basal", "ganglia", "was", "greater", "in", "continuation", "tapping", "than", "in", "synchronisation", "tapping", ".", "Parametric", "analysis", "revealed", "activity", "correlating", "with", "temporal", "complexity", "during", "initiate", "in", "bilateral", "supplementary", "and", "pre", "-", "supplementary", "motor", "cortex", "(", "SMA", "and", "preSMA", ")", ",", "rostral", "dorsal", "premotor", "cortex", "(", "PMC", ")", ",", "basal", "ganglia", ",", "and", "dorsolateral", "prefrontal", "cortex", "(", "DLPFC", ")", ",", "among", "other", "areas", ".", "During", "synchronise", ",", "correlated", "activity", "was", "observed", "in", "bilateral", "SMA", ",", "more", "caudal", "dorsal", "and", "ventral", "PMC", ",", "right", "DLPFC", "and", "right", "primary", "motor", "cortex", ".", "No", "correlated", "activity", "was", "observed", "during", "continue", "at", "P", "<", "0.01", "(", "corrected", ",", "cluster", "level", ")", ",", "though", "left", "angular", "gyrus", "was", "active", "at", "P", "<", "0.05", ".", "We", "suggest", "that", "the", "preSMA", "and", "rostral", "dorsal", "PMC", "activities", "during", "initiate", "may", "be", "associated", "with", "selection", "of", "timing", "parameters", ",", "while", "activation", "in", "centromedial", "prefrontal", "cortex", "during", "both", "initiate", "and", "synchronise", "may", "be", "associated", "with", "temporal", "error", "monitoring", "or", "correction", ".", "The", "absence", "of", "activity", "significantly", "correlated", "with", "temporal", "complexity", "during", "continue", "suggests", "that", ",", "once", "an", "overlearned", "timed", "movement", "sequence", "has", "been", "selected", "and", "initiated", ",", "there", "is", "no", "further", "adjustment", "of", "the", "timing", "control", "processes", "related", "to", "its", "continued", "production", "in", "absence", "of", "external", "cues", "." ]	[ "Intervention_Physical", "Outcome_Physical", "Participant_Condition" ]
Brain activity correlates is a Participant_Condition, synchronisation is a Intervention_Physical, continuation is a Intervention_Physical, paced finger tapping is a Intervention_Physical, Activity in parts of the human motor system is a Outcome_Physical, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) is a Intervention_Physical, continued tapping in absence of the auditory pacer is a Intervention_Physical, activation of bilateral SMA and basal ganglia is a Outcome_Physical	17402_task1	Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please typing these entity words according to sentence: Brain activity correlates, synchronisation, continuation, paced finger tapping, Activity in parts of the human motor system, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ), continued tapping in absence of the auditory pacer, activation of bilateral SMA and basal ganglia Options: Intervention_Physical, Outcome_Physical, Participant_Condition	[ "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .	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Brain activity correlates, synchronisation, continuation, paced finger tapping, Activity in parts of the human motor system, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ), continued tapping in absence of the auditory pacer, activation of bilateral SMA and basal ganglia	17402_task2	Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please extract entity words from the input sentence	[ "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .	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surgical treatment is a Intervention_Physical, cancer of the thyroid gland ] is a Participant_Condition	76651_task0	Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Physical, Participant_Condition	[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]	[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .	[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]	[ "Participant_Condition", "Intervention_Physical" ]
surgical treatment is a Intervention_Physical, cancer of the thyroid gland ] is a Participant_Condition	76651_task1	Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please typing these entity words according to sentence: surgical treatment, cancer of the thyroid gland ] Options: Intervention_Physical, Participant_Condition	[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]	[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .	[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]	[ "Participant_Condition", "Intervention_Physical" ]
surgical treatment, cancer of the thyroid gland ]	76651_task2	Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]	[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .	[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]	[ "Participant_Condition", "Intervention_Physical" ]
MurD is a protein, UMA is a compound	DS.d797_task0	Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: compound, protein	[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).	[ "MurD", "(", "UDP", "-", "N", "-", "acetylmuramoyl", "-", "L", "-", "alanine", ":D", "-", "glutamate", "ligase", ")", ",", "a", "three", "-", "domain", "bacterial", "protein", ",", "catalyses", "a", "highly", "specific", "incorporation", "of", "D", "-", "glutamate", "to", "the", "cytoplasmic", "intermediate", "UDP", "-", "N", "-", "acetyl", "-", "muramoyl", "-", "L", "-", "alanine", "(", "UMA", ")", "utilizing", "ATP", "hydrolysis", "to", "ADP", "and", "P(i", ")", "." ]	[ "compound", "protein" ]
MurD is a protein, UMA is a compound	DS.d797_task1	Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please typing these entity words according to sentence: MurD, UMA Options: compound, protein	[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).	[ "MurD", "(", "UDP", "-", "N", "-", "acetylmuramoyl", "-", "L", "-", "alanine", ":D", "-", "glutamate", "ligase", ")", ",", "a", "three", "-", "domain", "bacterial", "protein", ",", "catalyses", "a", "highly", "specific", "incorporation", "of", "D", "-", "glutamate", "to", "the", "cytoplasmic", "intermediate", "UDP", "-", "N", "-", "acetyl", "-", "muramoyl", "-", "L", "-", "alanine", "(", "UMA", ")", "utilizing", "ATP", "hydrolysis", "to", "ADP", "and", "P(i", ")", "." ]	[ "compound", "protein" ]
MurD, UMA	DS.d797_task2	Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please extract entity words from the input sentence	[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).	[ "MurD", "(", "UDP", "-", "N", "-", "acetylmuramoyl", "-", "L", "-", "alanine", ":D", "-", "glutamate", "ligase", ")", ",", "a", "three", "-", "domain", "bacterial", "protein", ",", "catalyses", "a", "highly", "specific", "incorporation", "of", "D", "-", "glutamate", "to", "the", "cytoplasmic", "intermediate", "UDP", "-", "N", "-", "acetyl", "-", "muramoyl", "-", "L", "-", "alanine", "(", "UMA", ")", "utilizing", "ATP", "hydrolysis", "to", "ADP", "and", "P(i", ")", "." ]	[ "compound", "protein" ]
Behandlung is an umlsterm, Hauptstammstenosen is an umlsterm, Koronararterie is an umlsterm, Notfall - Eingriff is an umlsterm, Myokardinfarkt is an umlsterm, perkutane transluminale Angioplastie is an umlsterm, Mortalitaet is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Koronararterie is an umlsterm, Risiko is an umlsterm, Notfall - Eingriff is an umlsterm, Risiko is an umlsterm	ZfuerKardiologie.00890508.ger.abstr_task0	Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .	[ "Die", "Behandlung", "hochgradiger", "symptomatischer", "Hauptstammstenosen", "der", "linken", "Koronararterie", "ist", "die", "operative", "Revaskularisation", ".", "Bei", "geschuetztem", "Hauptstamm", "durch", "vorangegangene", "Bypass", "-", "Operation", "oder", "als", "Notfall", "-", "Eingriff", "im", "akuten", "Myokardinfarkt", "mit", "kardiogenem", "Schock", "wird", "die", "perkutane", "transluminale", "Angioplastie", "als", "Behandlungsalternative", "durchgefuehrt", ".", "Die", "Durchsicht", "von", "262", "Interventionen", "ergab", "eine", "Mortalitaet", "der", "Intervention", "von", "9,1", "%", "(", "4/44", ")", "bei", "Patienten", "ohne", "Hauptstamm", "-", "Protektion", ",", "4,8", "%", "(", "1/21", ")", "bei", "Patienten", "mit", "Kollateralen", "und", "0,5", "%", "(", "1/197", ")", "bei", "Patienten", "mit", "offenem", "Bypass", "-", "Gefaess", "zu", "einem", "der", "Gefaesse", "der", "linken", "Koronararterie", ".", "Die", "koronare", "Agioplastie", "des", "ungeschuetzten", "Hauptstamms", "hat", "ein", "nicht", "akzeptables", "Risiko", "und", "sollte", "daher", "auch", "als", "Notfall", "-", "Eingriff", "nicht", "durchgefuehrt", "werden", ".", "Das", "Risiko", "der", "Hauptstamm", "-", "PTCA", "kann", "durch", "die", "vorgeschlagene", "Einteilung", "der", "Hauptstamm", "-", "Protektion", "durchgefuehrt", "werden", "." ]	[ "umlsterm" ]
Behandlung is an umlsterm, Hauptstammstenosen is an umlsterm, Koronararterie is an umlsterm, Notfall - Eingriff is an umlsterm, Myokardinfarkt is an umlsterm, perkutane transluminale Angioplastie is an umlsterm, Mortalitaet is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Koronararterie is an umlsterm, Risiko is an umlsterm, Notfall - Eingriff is an umlsterm, Risiko is an umlsterm	ZfuerKardiologie.00890508.ger.abstr_task1	Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please typing these entity words according to sentence: Behandlung, Hauptstammstenosen, Koronararterie, Notfall - Eingriff, Myokardinfarkt, perkutane transluminale Angioplastie, Mortalitaet, Patienten, Patienten, Patienten, Koronararterie, Risiko, Notfall - Eingriff, Risiko Options: umlsterm	[ "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .	[ "Die", "Behandlung", "hochgradiger", "symptomatischer", "Hauptstammstenosen", "der", "linken", "Koronararterie", "ist", "die", "operative", "Revaskularisation", ".", "Bei", "geschuetztem", "Hauptstamm", "durch", "vorangegangene", "Bypass", "-", "Operation", "oder", "als", "Notfall", "-", "Eingriff", "im", "akuten", "Myokardinfarkt", "mit", "kardiogenem", "Schock", "wird", "die", "perkutane", "transluminale", "Angioplastie", "als", "Behandlungsalternative", "durchgefuehrt", ".", "Die", "Durchsicht", "von", "262", "Interventionen", "ergab", "eine", "Mortalitaet", "der", "Intervention", "von", "9,1", "%", "(", "4/44", ")", "bei", "Patienten", "ohne", "Hauptstamm", "-", "Protektion", ",", "4,8", "%", "(", "1/21", ")", "bei", "Patienten", "mit", "Kollateralen", "und", "0,5", "%", "(", "1/197", ")", "bei", "Patienten", "mit", "offenem", "Bypass", "-", "Gefaess", "zu", "einem", "der", "Gefaesse", "der", "linken", "Koronararterie", ".", "Die", "koronare", "Agioplastie", "des", "ungeschuetzten", "Hauptstamms", "hat", "ein", "nicht", "akzeptables", "Risiko", "und", "sollte", "daher", "auch", "als", "Notfall", "-", "Eingriff", "nicht", "durchgefuehrt", "werden", ".", "Das", "Risiko", "der", "Hauptstamm", "-", "PTCA", "kann", "durch", "die", "vorgeschlagene", "Einteilung", "der", "Hauptstamm", "-", "Protektion", "durchgefuehrt", "werden", "." ]	[ "umlsterm" ]
Behandlung, Hauptstammstenosen, Koronararterie, Notfall - Eingriff, Myokardinfarkt, perkutane transluminale Angioplastie, Mortalitaet, Patienten, Patienten, Patienten, Koronararterie, Risiko, Notfall - Eingriff, Risiko	ZfuerKardiologie.00890508.ger.abstr_task2	Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please extract entity words from the input sentence	[ "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .	[ "Die", "Behandlung", "hochgradiger", "symptomatischer", "Hauptstammstenosen", "der", "linken", "Koronararterie", "ist", "die", "operative", "Revaskularisation", ".", "Bei", "geschuetztem", "Hauptstamm", "durch", "vorangegangene", "Bypass", "-", "Operation", "oder", "als", "Notfall", "-", "Eingriff", "im", "akuten", "Myokardinfarkt", "mit", "kardiogenem", "Schock", "wird", "die", "perkutane", "transluminale", "Angioplastie", "als", "Behandlungsalternative", "durchgefuehrt", ".", "Die", "Durchsicht", "von", "262", "Interventionen", "ergab", "eine", "Mortalitaet", "der", "Intervention", "von", "9,1", "%", "(", "4/44", ")", "bei", "Patienten", "ohne", "Hauptstamm", "-", "Protektion", ",", "4,8", "%", "(", "1/21", ")", "bei", "Patienten", "mit", "Kollateralen", "und", "0,5", "%", "(", "1/197", ")", "bei", "Patienten", "mit", "offenem", "Bypass", "-", "Gefaess", "zu", "einem", "der", "Gefaesse", "der", "linken", "Koronararterie", ".", "Die", "koronare", "Agioplastie", "des", "ungeschuetzten", "Hauptstamms", "hat", "ein", "nicht", "akzeptables", "Risiko", "und", "sollte", "daher", "auch", "als", "Notfall", "-", "Eingriff", "nicht", "durchgefuehrt", "werden", ".", "Das", "Risiko", "der", "Hauptstamm", "-", "PTCA", "kann", "durch", "die", "vorgeschlagene", "Einteilung", "der", "Hauptstamm", "-", "Protektion", "durchgefuehrt", "werden", "." ]	[ "umlsterm" ]
between 7 to 70 years is a Value, age is a Person, fluent in English is a Observation, plans to is a Mood, receive care is a Procedure, Community Health Center is a Visit, during the next year is a Temporal, signs and symptoms is a Scope, SSTI is a Condition	NCT02566928_inc_task0	Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Temporal, Condition, Value, Person, Observation, Visit, Procedure, Scope, Mood	[ "B-Value", "I-Value", "I-Value", "I-Value", "I-Value", "O", "B-Person", "O", "B-Observation", "I-Observation", "I-Observation", "O", "O", "O", "B-Mood", "I-Mood", "B-Procedure", "I-Procedure", "O", "O", "B-Visit", "I-Visit", "I-Visit", "B-Temporal", "I-Temporal", "I-Temporal", "I-Temporal", "O", "O", "O", "B-Scope", "I-Scope", "I-Scope", "O", "O", "B-Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent	[ "between", "7", "to", "70", "years", "of", "age", "\n", "fluent", "in", "English", "or", "Spanish", "\n", "plans", "to", "receive", "care", "in", "the", "Community", "Health", "Center", "during", "the", "next", "year", "\n", "presents", "with", "signs", "and", "symptoms", "of", "a", "SSTI", "\n", "willing", "/", "able", "to", "provide", "informed", "consent", "\n" ]	[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]
between 7 to 70 years is a Value, age is a Person, fluent in English is a Observation, plans to is a Mood, receive care is a Procedure, Community Health Center is a Visit, during the next year is a Temporal, signs and symptoms is a Scope, SSTI is a Condition	NCT02566928_inc_task1	Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please typing these entity words according to sentence: between 7 to 70 years, age, fluent in English, plans to, receive care, Community Health Center, during the next year, signs and symptoms, SSTI Options: Temporal, Condition, Value, Person, Observation, Visit, Procedure, Scope, Mood	[ "B-Value", "I-Value", "I-Value", "I-Value", "I-Value", "O", "B-Person", "O", "B-Observation", "I-Observation", "I-Observation", "O", "O", "O", "B-Mood", "I-Mood", "B-Procedure", "I-Procedure", "O", "O", "B-Visit", "I-Visit", "I-Visit", "B-Temporal", "I-Temporal", "I-Temporal", "I-Temporal", "O", "O", "O", "B-Scope", "I-Scope", "I-Scope", "O", "O", "B-Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent	[ "between", "7", "to", "70", "years", "of", "age", "\n", "fluent", "in", "English", "or", "Spanish", "\n", "plans", "to", "receive", "care", "in", "the", "Community", "Health", "Center", "during", "the", "next", "year", "\n", "presents", "with", "signs", "and", "symptoms", "of", "a", "SSTI", "\n", "willing", "/", "able", "to", "provide", "informed", "consent", "\n" ]	[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]
between 7 to 70 years, age, fluent in English, plans to, receive care, Community Health Center, during the next year, signs and symptoms, SSTI	NCT02566928_inc_task2	Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please extract entity words from the input sentence	[ "B-Value", "I-Value", "I-Value", "I-Value", "I-Value", "O", "B-Person", "O", "B-Observation", "I-Observation", "I-Observation", "O", "O", "O", "B-Mood", "I-Mood", "B-Procedure", "I-Procedure", "O", "O", "B-Visit", "I-Visit", "I-Visit", "B-Temporal", "I-Temporal", "I-Temporal", "I-Temporal", "O", "O", "O", "B-Scope", "I-Scope", "I-Scope", "O", "O", "B-Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent	[ "between", "7", "to", "70", "years", "of", "age", "\n", "fluent", "in", "English", "or", "Spanish", "\n", "plans", "to", "receive", "care", "in", "the", "Community", "Health", "Center", "during", "the", "next", "year", "\n", "presents", "with", "signs", "and", "symptoms", "of", "a", "SSTI", "\n", "willing", "/", "able", "to", "provide", "informed", "consent", "\n" ]	[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]
tissues is a Tissue, tissue is a Tissue, tree ring is a Tissue, leaf is a Organ, leaf is a Organ, stem tissue is a Tissue, crowns is a Organism_subdivision, woody tissue is a Tissue, branch wood is a Multi-tissue_structure, tree ring is a Tissue	PMID-17617824_task0	Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Multi-tissue_structure, Organism_subdivision, Tissue, Organ	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organism_subdivision", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Multi-tissue_structure", "I-Multi-tissue_structure", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.	[ "Rapid", "mixing", "between", "old", "and", "new", "C", "pools", "in", "the", "canopy", "of", "mature", "forest", "trees", ".", "\n", "Stable", "C", "isotope", "signals", "in", "plant", "tissues", "became", "a", "key", "tool", "in", "explaining", "growth", "responses", "to", "the", "environment", ".", "The", "technique", "is", "based", "on", "the", "fundamental", "assumption", "that", "the", "isotopic", "composition", "of", "a", "given", "unit", "of", "tissue", "(", "e.g", ".", "a", "tree", "ring", ")", "reflects", "the", "specific", "C", "uptake", "conditions", "in", "the", "leaf", "at", "a", "given", "time", ".", "Beyond", "the", "methodological", "implications", "of", "any", "deviation", "from", "this", "assumption", ",", "it", "is", "of", "physiological", "interest", "whether", "new", "C", "is", "transferred", "directly", "from", "sources", "(", "a", "photosynthesizing", "leaf", ")", "to", "structural", "sinks", "(", "e.g", ".", "adjacent", "stem", "tissue", ")", ",", "or", "inherently", "passes", "through", "existing", "(", "mobile", ")", "C", "pools", ",", "which", "may", "be", "of", "variable", "(", "older", ")", "age", ".", "Here", ",", "we", "explore", "the", "fate", "of", "(", "13)C", "-", "labelled", "photosynthates", "in", "the", "crowns", "of", "a", "30", "-", "35", "m", "tall", ",", "mixed", "forest", "using", "a", "canopy", "crane", ".", "In", "all", "nine", "study", "species", "labelled", "C", "reached", "woody", "tissue", "within", "2", "-", "9", "h", "after", "labelling", ".", "Four", "months", "later", ",", "very", "small", "signals", "were", "left", "in", "branch", "wood", "of", "Tilia", "suggesting", "that", "low", "mixing", "of", "new", ",", "labelled", "C", "with", "old", "C", "had", "taken", "place", ".", "In", "contrast", ",", "signals", "in", "Fagus", "and", "Quercus", "had", "increased", ",", "indicating", "more", "intense", "mixing", ".", "This", "species", "-", "specific", "mixing", "of", "new", "with", "old", "C", "pools", "is", "likely", "to", "mask", "year-", "or", "season", "-", "specific", "linkages", "between", "tree", "ring", "formation", "and", "climate", "and", "has", "considerable", "implications", "for", "climate", "reconstruction", "using", "stable", "isotopes", "as", "proxies", "for", "past", "climatic", "conditions", ".", "\n" ]	[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]
tissues is a Tissue, tissue is a Tissue, tree ring is a Tissue, leaf is a Organ, leaf is a Organ, stem tissue is a Tissue, crowns is a Organism_subdivision, woody tissue is a Tissue, branch wood is a Multi-tissue_structure, tree ring is a Tissue	PMID-17617824_task1	Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please typing these entity words according to sentence: tissues, tissue, tree ring, leaf, leaf, stem tissue, crowns, woody tissue, branch wood, tree ring Options: Multi-tissue_structure, Organism_subdivision, Tissue, Organ	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organism_subdivision", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Multi-tissue_structure", "I-Multi-tissue_structure", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.	[ "Rapid", "mixing", "between", "old", "and", "new", "C", "pools", "in", "the", "canopy", "of", "mature", "forest", "trees", ".", "\n", "Stable", "C", "isotope", "signals", "in", "plant", "tissues", "became", "a", "key", "tool", "in", "explaining", "growth", "responses", "to", "the", "environment", ".", "The", "technique", "is", "based", "on", "the", "fundamental", "assumption", "that", "the", "isotopic", "composition", "of", "a", "given", "unit", "of", "tissue", "(", "e.g", ".", "a", "tree", "ring", ")", "reflects", "the", "specific", "C", "uptake", "conditions", "in", "the", "leaf", "at", "a", "given", "time", ".", "Beyond", "the", "methodological", "implications", "of", "any", "deviation", "from", "this", "assumption", ",", "it", "is", "of", "physiological", "interest", "whether", "new", "C", "is", "transferred", "directly", "from", "sources", "(", "a", "photosynthesizing", "leaf", ")", "to", "structural", "sinks", "(", "e.g", ".", "adjacent", "stem", "tissue", ")", ",", "or", "inherently", "passes", "through", "existing", "(", "mobile", ")", "C", "pools", ",", "which", "may", "be", "of", "variable", "(", "older", ")", "age", ".", "Here", ",", "we", "explore", "the", "fate", "of", "(", "13)C", "-", "labelled", "photosynthates", "in", "the", "crowns", "of", "a", "30", "-", "35", "m", "tall", ",", "mixed", "forest", "using", "a", "canopy", "crane", ".", "In", "all", "nine", "study", "species", "labelled", "C", "reached", "woody", "tissue", "within", "2", "-", "9", "h", "after", "labelling", ".", "Four", "months", "later", ",", "very", "small", "signals", "were", "left", "in", "branch", "wood", "of", "Tilia", "suggesting", "that", "low", "mixing", "of", "new", ",", "labelled", "C", "with", "old", "C", "had", "taken", "place", ".", "In", "contrast", ",", "signals", "in", "Fagus", "and", "Quercus", "had", "increased", ",", "indicating", "more", "intense", "mixing", ".", "This", "species", "-", "specific", "mixing", "of", "new", "with", "old", "C", "pools", "is", "likely", "to", "mask", "year-", "or", "season", "-", "specific", "linkages", "between", "tree", "ring", "formation", "and", "climate", "and", "has", "considerable", "implications", "for", "climate", "reconstruction", "using", "stable", "isotopes", "as", "proxies", "for", "past", "climatic", "conditions", ".", "\n" ]	[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]
tissues, tissue, tree ring, leaf, leaf, stem tissue, crowns, woody tissue, branch wood, tree ring	PMID-17617824_task2	Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organ", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Organism_subdivision", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Multi-tissue_structure", "I-Multi-tissue_structure", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.	[ "Rapid", "mixing", "between", "old", "and", "new", "C", "pools", "in", "the", "canopy", "of", "mature", "forest", "trees", ".", "\n", "Stable", "C", "isotope", "signals", "in", "plant", "tissues", "became", "a", "key", "tool", "in", "explaining", "growth", "responses", "to", "the", "environment", ".", "The", "technique", "is", "based", "on", "the", "fundamental", "assumption", "that", "the", "isotopic", "composition", "of", "a", "given", "unit", "of", "tissue", "(", "e.g", ".", "a", "tree", "ring", ")", "reflects", "the", "specific", "C", "uptake", "conditions", "in", "the", "leaf", "at", "a", "given", "time", ".", "Beyond", "the", "methodological", "implications", "of", "any", "deviation", "from", "this", "assumption", ",", "it", "is", "of", "physiological", "interest", "whether", "new", "C", "is", "transferred", "directly", "from", "sources", "(", "a", "photosynthesizing", "leaf", ")", "to", "structural", "sinks", "(", "e.g", ".", "adjacent", "stem", "tissue", ")", ",", "or", "inherently", "passes", "through", "existing", "(", "mobile", ")", "C", "pools", ",", "which", "may", "be", "of", "variable", "(", "older", ")", "age", ".", "Here", ",", "we", "explore", "the", "fate", "of", "(", "13)C", "-", "labelled", "photosynthates", "in", "the", "crowns", "of", "a", "30", "-", "35", "m", "tall", ",", "mixed", "forest", "using", "a", "canopy", "crane", ".", "In", "all", "nine", "study", "species", "labelled", "C", "reached", "woody", "tissue", "within", "2", "-", "9", "h", "after", "labelling", ".", "Four", "months", "later", ",", "very", "small", "signals", "were", "left", "in", "branch", "wood", "of", "Tilia", "suggesting", "that", "low", "mixing", "of", "new", ",", "labelled", "C", "with", "old", "C", "had", "taken", "place", ".", "In", "contrast", ",", "signals", "in", "Fagus", "and", "Quercus", "had", "increased", ",", "indicating", "more", "intense", "mixing", ".", "This", "species", "-", "specific", "mixing", "of", "new", "with", "old", "C", "pools", "is", "likely", "to", "mask", "year-", "or", "season", "-", "specific", "linkages", "between", "tree", "ring", "formation", "and", "climate", "and", "has", "considerable", "implications", "for", "climate", "reconstruction", "using", "stable", "isotopes", "as", "proxies", "for", "past", "climatic", "conditions", ".", "\n" ]	[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]
Kindern is an umlsterm, Diabetes mellitus is an umlsterm, Hypoglykaemie is an umlsterm, jugendlichen is an umlsterm, Eltern is an umlsterm, Ethikkommission is an umlsterm, Insulin - induzierte is an umlsterm	MonatsschriftKinderheilkunde.71450120.ger.abstr_task0	Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]	Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .	[ "Fragestellung", ":", "Um", "die", "bei", "Kindern", "mit", "juvenilem", "Diabetes", "mellitus", "wenig", "untersuchten", "Erstsymptome", "und", "die", "adrenerge", "Antwort", "in", "der", "Hypoglykaemie", "zu", "charakterisieren", ",", "fuehrten", "wir", "bei", "23", "jugendlichen", "Diabetikern", "in", "Begleitung", "ihrer", "Eltern", "eine", "von", "der", "Ethikkommission", "genehmigte", "milde", "Insulin", "-", "induzierte", "Unterzuckerung", "durch", "." ]	[ "umlsterm" ]
Kindern is an umlsterm, Diabetes mellitus is an umlsterm, Hypoglykaemie is an umlsterm, jugendlichen is an umlsterm, Eltern is an umlsterm, Ethikkommission is an umlsterm, Insulin - induzierte is an umlsterm	MonatsschriftKinderheilkunde.71450120.ger.abstr_task1	Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please typing these entity words according to sentence: Kindern, Diabetes mellitus, Hypoglykaemie, jugendlichen, Eltern, Ethikkommission, Insulin - induzierte Options: umlsterm	[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]	Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .	[ "Fragestellung", ":", "Um", "die", "bei", "Kindern", "mit", "juvenilem", "Diabetes", "mellitus", "wenig", "untersuchten", "Erstsymptome", "und", "die", "adrenerge", "Antwort", "in", "der", "Hypoglykaemie", "zu", "charakterisieren", ",", "fuehrten", "wir", "bei", "23", "jugendlichen", "Diabetikern", "in", "Begleitung", "ihrer", "Eltern", "eine", "von", "der", "Ethikkommission", "genehmigte", "milde", "Insulin", "-", "induzierte", "Unterzuckerung", "durch", "." ]	[ "umlsterm" ]
Kindern, Diabetes mellitus, Hypoglykaemie, jugendlichen, Eltern, Ethikkommission, Insulin - induzierte	MonatsschriftKinderheilkunde.71450120.ger.abstr_task2	Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]	Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .	[ "Fragestellung", ":", "Um", "die", "bei", "Kindern", "mit", "juvenilem", "Diabetes", "mellitus", "wenig", "untersuchten", "Erstsymptome", "und", "die", "adrenerge", "Antwort", "in", "der", "Hypoglykaemie", "zu", "charakterisieren", ",", "fuehrten", "wir", "bei", "23", "jugendlichen", "Diabetikern", "in", "Begleitung", "ihrer", "Eltern", "eine", "von", "der", "Ethikkommission", "genehmigte", "milde", "Insulin", "-", "induzierte", "Unterzuckerung", "durch", "." ]	[ "umlsterm" ]
putative benefits is a Outcome_Other, montelukast is a Intervention_Pharmacological, moderate persistent asthmatics is a Participant_Condition, patients with moderate to severe asthma is a Participant_Condition, ICS is a Intervention_Pharmacological, salmeterol is a Intervention_Pharmacological, Twenty is a Participant_Sample-size, moderate to severe persistent asthmatics is a Participant_Condition, montelukast 10 mg daily is a Intervention_Pharmacological, placebo is a Intervention_Control, sequence effects is a Outcome_Other, Methacholine PD20 values is a Outcome_Physical, Lung function deteriorated is a Outcome_Physical, FEF25 - 75 is a Outcome_Physical, FEV1 is a Outcome_Physical, diurnal peak expiratory flow is a Outcome_Physical, symptoms is a Outcome_Physical, salbutamol use is a Outcome_Other	13217_task0	Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Pharmacological, Intervention_Control, Participant_Condition, Outcome_Physical, Participant_Sample-size, Outcome_Other	[ "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "B-Intervention_Pharmacological", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Sample-size", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "O", "B-Intervention_Control", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "B-Outcome_Physical", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .	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putative benefits is a Outcome_Other, montelukast is a Intervention_Pharmacological, moderate persistent asthmatics is a Participant_Condition, patients with moderate to severe asthma is a Participant_Condition, ICS is a Intervention_Pharmacological, salmeterol is a Intervention_Pharmacological, Twenty is a Participant_Sample-size, moderate to severe persistent asthmatics is a Participant_Condition, montelukast 10 mg daily is a Intervention_Pharmacological, placebo is a Intervention_Control, sequence effects is a Outcome_Other, Methacholine PD20 values is a Outcome_Physical, Lung function deteriorated is a Outcome_Physical, FEF25 - 75 is a Outcome_Physical, FEV1 is a Outcome_Physical, diurnal peak expiratory flow is a Outcome_Physical, symptoms is a Outcome_Physical, salbutamol use is a Outcome_Other	13217_task1	Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please typing these entity words according to sentence: putative benefits, montelukast, moderate persistent asthmatics, patients with moderate to severe asthma, ICS, salmeterol, Twenty, moderate to severe persistent asthmatics, montelukast 10 mg daily, placebo, sequence effects, Methacholine PD20 values, Lung function deteriorated, FEF25 - 75, FEV1, diurnal peak expiratory flow, symptoms, salbutamol use Options: Intervention_Pharmacological, Intervention_Control, Participant_Condition, Outcome_Physical, Participant_Sample-size, Outcome_Other	[ "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "B-Intervention_Pharmacological", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Sample-size", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "O", "B-Intervention_Control", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "B-Outcome_Physical", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .	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putative benefits, montelukast, moderate persistent asthmatics, patients with moderate to severe asthma, ICS, salmeterol, Twenty, moderate to severe persistent asthmatics, montelukast 10 mg daily, placebo, sequence effects, Methacholine PD20 values, Lung function deteriorated, FEF25 - 75, FEV1, diurnal peak expiratory flow, symptoms, salbutamol use	13217_task2	Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "B-Intervention_Pharmacological", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "B-Intervention_Pharmacological", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Sample-size", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "O", "B-Intervention_Control", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "B-Outcome_Physical", "O", "B-Outcome_Other", "I-Outcome_Other", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .	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psychoanalysis is an umlsterm, elements is an umlsterm, publications is an umlsterm, films is an umlsterm, psychoanalysis is an umlsterm, work is an umlsterm, patient is an umlsterm, confusion is an umlsterm, patient is an umlsterm, abuse is an umlsterm, psychoanalysis is an umlsterm, thesis is an umlsterm, psychoanalysis is an umlsterm, body - therapy is an umlsterm	ForumDerPsychoanalyse.80140342.eng.abstr_task0	Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O" ]	The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .	[ "The", "author", "discusses", "critically", "the", "\"", "extension", "\"", "of", "psychoanalysis", "through", "\"", "body", "-", "therapeutical", "elements", "\"", "by", "Tilmann", "Moser", ".", "She", "demonstrates", "on", "the", "basis", "of", "the", "publications", "of", "Moser", "on", "this", "topic", ",", "especially", "of", "his", "didactical", "films", "about", "psychoanalysis", "and", "body", "work", ",", "how", "some", "acts", "between", "therapist", "and", "patient", "which", "are", "to", "understand", "sexually", "and", "are", "also", "experienced", "as", "such", ",", "are", "systematically", "reinterpreted", "by", "Moser", "as", "\"", "preverbal", "\"", "and", "\"", "preoedipal", "\"", ".", "This", "reinterpretation", "leads", "to", "the", "manipulative", "confusion", "of", "the", "patient", "and", "corresponds", "to", "the", "structure", "of", "abuse", "sceneries", ".", "Theoretical", "reflections", "about", "healing", "phantasies", "and", "about", "the", "concept", "of", "abstinence", "in", "psychoanalysis", "follow", "and", "on", "their", "basis", "the", "thesis", "is", "substantiated", ",", "that", "psychoanalysis", "and", "body", "-", "therapy", "are", "incompatible", "concepts", "." ]	[ "umlsterm" ]
psychoanalysis is an umlsterm, elements is an umlsterm, publications is an umlsterm, films is an umlsterm, psychoanalysis is an umlsterm, work is an umlsterm, patient is an umlsterm, confusion is an umlsterm, patient is an umlsterm, abuse is an umlsterm, psychoanalysis is an umlsterm, thesis is an umlsterm, psychoanalysis is an umlsterm, body - therapy is an umlsterm	ForumDerPsychoanalyse.80140342.eng.abstr_task1	Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please typing these entity words according to sentence: psychoanalysis, elements, publications, films, psychoanalysis, work, patient, confusion, patient, abuse, psychoanalysis, thesis, psychoanalysis, body - therapy Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O" ]	The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .	[ "The", "author", "discusses", "critically", "the", "\"", "extension", "\"", "of", "psychoanalysis", "through", "\"", "body", "-", "therapeutical", "elements", "\"", "by", "Tilmann", "Moser", ".", "She", "demonstrates", "on", "the", "basis", "of", "the", "publications", "of", "Moser", "on", "this", "topic", ",", "especially", "of", "his", "didactical", "films", "about", "psychoanalysis", "and", "body", "work", ",", "how", "some", "acts", "between", "therapist", "and", "patient", "which", "are", "to", "understand", "sexually", "and", "are", "also", "experienced", "as", "such", ",", "are", "systematically", "reinterpreted", "by", "Moser", "as", "\"", "preverbal", "\"", "and", "\"", "preoedipal", "\"", ".", "This", "reinterpretation", "leads", "to", "the", "manipulative", "confusion", "of", "the", "patient", "and", "corresponds", "to", "the", "structure", "of", "abuse", "sceneries", ".", "Theoretical", "reflections", "about", "healing", "phantasies", "and", "about", "the", "concept", "of", "abstinence", "in", "psychoanalysis", "follow", "and", "on", "their", "basis", "the", "thesis", "is", "substantiated", ",", "that", "psychoanalysis", "and", "body", "-", "therapy", "are", "incompatible", "concepts", "." ]	[ "umlsterm" ]
psychoanalysis, elements, publications, films, psychoanalysis, work, patient, confusion, patient, abuse, psychoanalysis, thesis, psychoanalysis, body - therapy	ForumDerPsychoanalyse.80140342.eng.abstr_task2	Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O" ]	The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .	[ "The", "author", "discusses", "critically", "the", "\"", "extension", "\"", "of", "psychoanalysis", "through", "\"", "body", "-", "therapeutical", "elements", "\"", "by", "Tilmann", "Moser", ".", "She", "demonstrates", "on", "the", "basis", "of", "the", "publications", "of", "Moser", "on", "this", "topic", ",", "especially", "of", "his", "didactical", "films", "about", "psychoanalysis", "and", "body", "work", ",", "how", "some", "acts", "between", "therapist", "and", "patient", "which", "are", "to", "understand", "sexually", "and", "are", "also", "experienced", "as", "such", ",", "are", "systematically", "reinterpreted", "by", "Moser", "as", "\"", "preverbal", "\"", "and", "\"", "preoedipal", "\"", ".", "This", "reinterpretation", "leads", "to", "the", "manipulative", "confusion", "of", "the", "patient", "and", "corresponds", "to", "the", "structure", "of", "abuse", "sceneries", ".", "Theoretical", "reflections", "about", "healing", "phantasies", "and", "about", "the", "concept", "of", "abstinence", "in", "psychoanalysis", "follow", "and", "on", "their", "basis", "the", "thesis", "is", "substantiated", ",", "that", "psychoanalysis", "and", "body", "-", "therapy", "are", "incompatible", "concepts", "." ]	[ "umlsterm" ]
Colour is an umlsterm, measurements is an umlsterm, cocaine is an umlsterm, measurements is an umlsterm, halogen is an umlsterm, light is an umlsterm, standard is an umlsterm, Colorimetric is an umlsterm, classification is an umlsterm, chemical composition is an umlsterm, method is an umlsterm, orientation is an umlsterm, origin is an umlsterm	Rechtsmedizin.90090218.eng.abstr_task0	Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]	Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .	[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "Lab-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "Lab-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]	[ "umlsterm" ]
Colour is an umlsterm, measurements is an umlsterm, cocaine is an umlsterm, measurements is an umlsterm, halogen is an umlsterm, light is an umlsterm, standard is an umlsterm, Colorimetric is an umlsterm, classification is an umlsterm, chemical composition is an umlsterm, method is an umlsterm, orientation is an umlsterm, origin is an umlsterm	Rechtsmedizin.90090218.eng.abstr_task1	Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please typing these entity words according to sentence: Colour, measurements, cocaine, measurements, halogen, light, standard, Colorimetric, classification, chemical composition, method, orientation, origin Options: umlsterm	[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]	Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .	[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "Lab-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "Lab-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]	[ "umlsterm" ]
Colour, measurements, cocaine, measurements, halogen, light, standard, Colorimetric, classification, chemical composition, method, orientation, origin	Rechtsmedizin.90090218.eng.abstr_task2	Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please extract entity words from the input sentence	[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]	Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-Lab-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-Lab-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .	[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "Lab-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "Lab-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]	[ "umlsterm" ]
Epstein - Barr virus BamHI W promoter is a DNA_domain_or_region	69080_task0	Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: DNA_domain_or_region	[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.	[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]	[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]
Epstein - Barr virus BamHI W promoter is a DNA_domain_or_region	69080_task1	Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please typing these entity words according to sentence: Epstein - Barr virus BamHI W promoter Options: DNA_domain_or_region	[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.	[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]	[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]
Epstein - Barr virus BamHI W promoter	69080_task2	Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.	[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]	[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]
actin is a Individual_protein, fimbrin is a Individual_protein	803_task0	Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Individual_protein	[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]	The structure of an actin-crosslinking domain from human fimbrin.	[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]	[ "Individual_protein" ]
actin is a Individual_protein, fimbrin is a Individual_protein	803_task1	Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please typing these entity words according to sentence: actin, fimbrin Options: Individual_protein	[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]	The structure of an actin-crosslinking domain from human fimbrin.	[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]	[ "Individual_protein" ]
actin, fimbrin	803_task2	Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]	The structure of an actin-crosslinking domain from human fimbrin.	[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]	[ "Individual_protein" ]
fractures is an umlsterm, spine is an umlsterm, separation is an umlsterm, injury is an umlsterm, spinal cord is an umlsterm, fracture is an umlsterm, arc is an umlsterm, fracture is an umlsterm, set is an umlsterm, X - rays is an umlsterm, trauma is an umlsterm, treatment is an umlsterm, open is an umlsterm	Trauma+Berufskrankheit.80010071.eng.abstr_task0	Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .	[ "Complete", "dislocated", "fractures", "of", "the", "thoracic", "spine", "may", "have", "no", "neurological", "deficits", "if", "separation", "is", "present", "in", "the", "middle", "of", "the", "dorsal", "column", ".", "In", "this", "case", "there", "is", "no", "injury", "to", "the", "spinal", "cord", ",", "because", "the", "\"", "saving", "fracture", "\"", "of", "the", "vertebral", "arc", "prevents", "it", ".", "One", "case", "of", "a", "severe", "dislocated", "fracture", "at", "T11", "-", "12", "is", "reported", ".", "In", "practice", ",", "a", "complete", "set", "of", "X", "-", "rays", "should", "be", "done", "after", "high", "-", "speed", "trauma", ",", "even", "if", "no", "neurological", "deficit", "is", "present", ".", "The", "treatment", "is", "operative", "by", "open", "reduction", "and", "fusion", "from", "the", "ventral", "or", "dorsal", "column", "." ]	[ "umlsterm" ]
fractures is an umlsterm, spine is an umlsterm, separation is an umlsterm, injury is an umlsterm, spinal cord is an umlsterm, fracture is an umlsterm, arc is an umlsterm, fracture is an umlsterm, set is an umlsterm, X - rays is an umlsterm, trauma is an umlsterm, treatment is an umlsterm, open is an umlsterm	Trauma+Berufskrankheit.80010071.eng.abstr_task1	Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please typing these entity words according to sentence: fractures, spine, separation, injury, spinal cord, fracture, arc, fracture, set, X - rays, trauma, treatment, open Options: umlsterm	[ "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .	[ "Complete", "dislocated", "fractures", "of", "the", "thoracic", "spine", "may", "have", "no", "neurological", "deficits", "if", "separation", "is", "present", "in", "the", "middle", "of", "the", "dorsal", "column", ".", "In", "this", "case", "there", "is", "no", "injury", "to", "the", "spinal", "cord", ",", "because", "the", "\"", "saving", "fracture", "\"", "of", "the", "vertebral", "arc", "prevents", "it", ".", "One", "case", "of", "a", "severe", "dislocated", "fracture", "at", "T11", "-", "12", "is", "reported", ".", "In", "practice", ",", "a", "complete", "set", "of", "X", "-", "rays", "should", "be", "done", "after", "high", "-", "speed", "trauma", ",", "even", "if", "no", "neurological", "deficit", "is", "present", ".", "The", "treatment", "is", "operative", "by", "open", "reduction", "and", "fusion", "from", "the", "ventral", "or", "dorsal", "column", "." ]	[ "umlsterm" ]
fractures, spine, separation, injury, spinal cord, fracture, arc, fracture, set, X - rays, trauma, treatment, open	Trauma+Berufskrankheit.80010071.eng.abstr_task2	Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please extract entity words from the input sentence	[ "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .	[ "Complete", "dislocated", "fractures", "of", "the", "thoracic", "spine", "may", "have", "no", "neurological", "deficits", "if", "separation", "is", "present", "in", "the", "middle", "of", "the", "dorsal", "column", ".", "In", "this", "case", "there", "is", "no", "injury", "to", "the", "spinal", "cord", ",", "because", "the", "\"", "saving", "fracture", "\"", "of", "the", "vertebral", "arc", "prevents", "it", ".", "One", "case", "of", "a", "severe", "dislocated", "fracture", "at", "T11", "-", "12", "is", "reported", ".", "In", "practice", ",", "a", "complete", "set", "of", "X", "-", "rays", "should", "be", "done", "after", "high", "-", "speed", "trauma", ",", "even", "if", "no", "neurological", "deficit", "is", "present", ".", "The", "treatment", "is", "operative", "by", "open", "reduction", "and", "fusion", "from", "the", "ventral", "or", "dorsal", "column", "." ]	[ "umlsterm" ]
Matías is a NOMBRE_SUJETO_ASISTENCIA, San Martin Fernandez is a NOMBRE_SUJETO_ASISTENCIA, 2756849 is a ID_SUJETO_ASISTENCIA, 47 98563794 10 is a ID_ASEGURAMIENTO, Pontevedra is a TERRITORIO, 36071 is a TERRITORIO, 07/05/1990 is a FECHAS, España is a PAIS, 09/04/2012 is a FECHAS, 7435703 is a ID_CONTACTO_ASISTENCIAL, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, 36 36 15748 is a ID_TITULACION_PERSONAL_SANITARIO, varón is a SEXO_SUJETO_ASISTENCIA, 21 años is a EDAD_SUJETO_ASISTENCIA, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, Hospital de Montecelo is a HOSPITAL, 36071 is a TERRITORIO, Pontevedra is a TERRITORIO, enrique.alemparte.pardavila@sergas.es is a CORREO_ELECTRONICO	158_task0	Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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Matías is a NOMBRE_SUJETO_ASISTENCIA, San Martin Fernandez is a NOMBRE_SUJETO_ASISTENCIA, 2756849 is a ID_SUJETO_ASISTENCIA, 47 98563794 10 is a ID_ASEGURAMIENTO, Pontevedra is a TERRITORIO, 36071 is a TERRITORIO, 07/05/1990 is a FECHAS, España is a PAIS, 09/04/2012 is a FECHAS, 7435703 is a ID_CONTACTO_ASISTENCIAL, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, 36 36 15748 is a ID_TITULACION_PERSONAL_SANITARIO, varón is a SEXO_SUJETO_ASISTENCIA, 21 años is a EDAD_SUJETO_ASISTENCIA, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, Hospital de Montecelo is a HOSPITAL, 36071 is a TERRITORIO, Pontevedra is a TERRITORIO, enrique.alemparte.pardavila@sergas.es is a CORREO_ELECTRONICO	158_task1	Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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Matías, San Martin Fernandez, 2756849, 47 98563794 10, Pontevedra, 36071, 07/05/1990, España, 09/04/2012, 7435703, Enrique Alemparte Pardavila, 36 36 15748, varón, 21 años, Enrique Alemparte Pardavila, Hospital de Montecelo, 36071, Pontevedra, enrique.alemparte.pardavila@sergas.es	158_task2	Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. 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transient ulnar artery compression is a Intervention_Physical, Patients referred for coronary angiography is a Participant_Condition, very - low - dose heparin is a Intervention_Pharmacological, 465 patients is a Participant_Sample-size, incidence of initial RAO is a Outcome_Physical	49862_task0	Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . 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Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .	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transient ulnar artery compression is a Intervention_Physical, Patients referred for coronary angiography is a Participant_Condition, very - low - dose heparin is a Intervention_Pharmacological, 465 patients is a Participant_Sample-size, incidence of initial RAO is a Outcome_Physical	49862_task1	Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . Instructions: please typing these entity words according to sentence: transient ulnar artery compression, Patients referred for coronary angiography, very - low - dose heparin, 465 patients, incidence of initial RAO Options: Intervention_Pharmacological, Intervention_Physical, Participant_Condition, Outcome_Physical, Participant_Sample-size	[ "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "B-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Sample-size", "I-Participant_Sample-size", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .	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transient ulnar artery compression, Patients referred for coronary angiography, very - low - dose heparin, 465 patients, incidence of initial RAO	49862_task2	Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "B-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "I-Intervention_Pharmacological", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Participant_Sample-size", "I-Participant_Sample-size", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .	[ "Efficacy", "and", "safety", "of", "transient", "ulnar", "artery", "compression", "to", "recanalize", "acute", "radial", "artery", "occlusion", "after", "transradial", "catheterization", ".", "Radial", "artery", "occlusion", "(", "RAO", ")", "can", "result", "from", "transradial", "catheterization", ".", "We", "compared", "the", "incidence", "of", "RAO", "with", "2", "heparin", "dosage", "regimens", "after", "transradial", "coronary", "angiography", ",", "and", "we", "evaluated", "the", "efficacy", "and", "safety", "of", "transient", "homolateral", "ulnar", "artery", "compression", "to", "achieve", "acute", "radial", "artery", "recanalization", ".", "Patients", "referred", "for", "coronary", "angiography", "were", "randomized", "to", "very", "-", "low", "-", "dose", "heparin", "(", "2,000", "IU", ")", "or", "low", "-", "dose", "heparin", "(", "5,000", "IU", ")", ".", "On", "sheath", "removal", ",", "hemostasis", "was", "obtained", "using", "the", "TR", "band", "with", "a", "plethysmography", "-", "guided", "patent", "hemostasis", "technique", ".", "In", "the", "case", "of", "RAO", "as", "assessed", "by", "duplex", "ultrasonography", "3", "to", "4", "hours", "after", "hemostasis", ",", "immediate", "1-hour", "ulnar", "artery", "compression", "was", "applied", ".", "Hematomas", ">", "15", "cm", "(", "2", ")", "were", "also", "assessed", ".", "We", "randomized", "465", "patients", ",", "222", "in", "the", "2,000-IU", "group", "and", "243", "in", "the", "5,000-IU", "group", ".", "The", "baseline", "and", "procedural", "characteristics", "were", "comparable", "in", "both", "groups", ".", "The", "incidence", "of", "initial", "RAO", "was", "5.9", "%", "in", "the", "2,000-IU", "group", "and", "2.9", "%", "in", "the", "5,000-IU", "group", "(", "p", "=", "0.17", ")", ",", "with", "a", "compression", "time", "of", "2.10", "±", "0.78", "hours", "and", "2.25", "±", "0.82", "hours", ",", "respectively", "(", "p", "=", "0.051", ")", ".", "After", "ulnar", "artery", "compression", ",", "the", "final", "incidence", "of", "RAO", "was", "4.1", "%", "in", "the", "2,000-IU", "group", "and", "0.8", "%", "in", "the", "5,000-IU", "group", "(", "p", "=", "0.03", ")", ".", "The", "incidence", "of", "local", "hematoma", "was", "2.3", "%", "and", "3.7", "%", "in", "the", "2,000-", "and", "5,000-IU", "groups", ",", "respectively", "(", "p", "=", "0.42", ")", ".", "In", "conclusion", ",", "acute", "RAO", "after", "transradial", "catheterization", "can", "be", "recanalized", "by", "early", "1-hour", "homolateral", "ulnar", "artery", "compression", ".", "This", "simple", "nonpharmacologic", "method", "was", "effective", "and", "safe", "in", "patients", "with", "very", "-", "low-", "and", "low", "-", "dose", "heparin", ".", "Nevertheless", ",", "the", "incidence", "of", "final", "RAO", "remained", "significantly", "lower", "after", "a", "higher", "anticoagulation", "level", "." ]	[ "Participant_Condition", "Intervention_Physical", "Outcome_Physical", "Intervention_Pharmacological", "Participant_Sample-size" ]
cryotherapy is an umlsterm, morphological is an umlsterm, eyes is an umlsterm, retinopathy of prematurity is an umlsterm, visual acuity is an umlsterm, eyes is an umlsterm, cryocoagulation is an umlsterm, hospital is an umlsterm, gestational age is an umlsterm	DerOpthalmologe.90960786.eng.abstr_task0	Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O" ]	Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .	[ "Background", ":", "The", "results", "of", "the", "Cryo", "-", "ROP", "group", "showed", "that", "cryotherapy", "significantly", "reduces", "the", "rate", "of", "adverse", "morphological", "and", "functional", "outcome", "of", "eyes", "with", "threshold", "retinopathy", "of", "prematurity", ".", "Structural", "status", "and", "visual", "acuity", "of", "48", "eyes", "which", "consecutively", "underwent", "cryocoagulation", "in", "our", "hospital", "between", "1990", "and", "1994", "were", "examined", "at", "2", "years", "corrected", "gestational", "age", "." ]	[ "umlsterm" ]
cryotherapy is an umlsterm, morphological is an umlsterm, eyes is an umlsterm, retinopathy of prematurity is an umlsterm, visual acuity is an umlsterm, eyes is an umlsterm, cryocoagulation is an umlsterm, hospital is an umlsterm, gestational age is an umlsterm	DerOpthalmologe.90960786.eng.abstr_task1	Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please typing these entity words according to sentence: cryotherapy, morphological, eyes, retinopathy of prematurity, visual acuity, eyes, cryocoagulation, hospital, gestational age Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O" ]	Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .	[ "Background", ":", "The", "results", "of", "the", "Cryo", "-", "ROP", "group", "showed", "that", "cryotherapy", "significantly", "reduces", "the", "rate", "of", "adverse", "morphological", "and", "functional", "outcome", "of", "eyes", "with", "threshold", "retinopathy", "of", "prematurity", ".", "Structural", "status", "and", "visual", "acuity", "of", "48", "eyes", "which", "consecutively", "underwent", "cryocoagulation", "in", "our", "hospital", "between", "1990", "and", "1994", "were", "examined", "at", "2", "years", "corrected", "gestational", "age", "." ]	[ "umlsterm" ]
cryotherapy, morphological, eyes, retinopathy of prematurity, visual acuity, eyes, cryocoagulation, hospital, gestational age	DerOpthalmologe.90960786.eng.abstr_task2	Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O" ]	Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .	[ "Background", ":", "The", "results", "of", "the", "Cryo", "-", "ROP", "group", "showed", "that", "cryotherapy", "significantly", "reduces", "the", "rate", "of", "adverse", "morphological", "and", "functional", "outcome", "of", "eyes", "with", "threshold", "retinopathy", "of", "prematurity", ".", "Structural", "status", "and", "visual", "acuity", "of", "48", "eyes", "which", "consecutively", "underwent", "cryocoagulation", "in", "our", "hospital", "between", "1990", "and", "1994", "were", "examined", "at", "2", "years", "corrected", "gestational", "age", "." ]	[ "umlsterm" ]
patients is an umlsterm, major depression is an umlsterm, disorder is an umlsterm, sleep deprivation is an umlsterm, TSD is an umlsterm, TSD is an umlsterm, naps is an umlsterm, night 's is an umlsterm, methods is an umlsterm, sleep is an umlsterm, mood is an umlsterm, male is an umlsterm, patients is an umlsterm, major depression is an umlsterm, treatment is an umlsterm, patients is an umlsterm, mood is an umlsterm, treatment is an umlsterm, patients is an umlsterm	DerNervenarzt.80690066.eng.abstr_task0	Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .	[ "Approximately", "60", "%", "of", "patients", "with", "major", "depression", "disorder", "show", "a", "beneficial", "response", "to", "total", "sleep", "deprivation", "(", "TSD", ")", ",", "but", "the", "positive", "effect", "of", "TSD", "is", "short", ",", "and", "naps", "or", "the", "following", "night", "'s", "sleep", "destroy", "it", ".", "Various", "methods", "have", "been", "tried", "to", "stabilize", "the", "positive", "sleep", "-", "deprivation", "effect", ".", "A", "consecutive", "1-week", "advance", "in", "the", "sleep", "phase", "stabilized", "mood", "in", "more", "than", "50", "%", "of", "the", "sleep", "-", "deprivation", "responders", ".", "We", "examined", "40", "male", "patients", "with", "major", "depression", "who", "in", "addition", "to", "medical", "treatment", "took", "part", "in", "a", "phase", "advance", "study", "to", "prove", "possible", "synergistic", "effects", ".", "About", "60", "%", "of", "the", "patients", "showed", "positive", "mood", "stabilization", "after", "1-week", "of", "treatment", "when", "the", "patients", "were", "sleep", "-", "deprivation", "responders", ".", "These", "results", "support", "data", "from", "other", "groups", "." ]	[ "umlsterm" ]
patients is an umlsterm, major depression is an umlsterm, disorder is an umlsterm, sleep deprivation is an umlsterm, TSD is an umlsterm, TSD is an umlsterm, naps is an umlsterm, night 's is an umlsterm, methods is an umlsterm, sleep is an umlsterm, mood is an umlsterm, male is an umlsterm, patients is an umlsterm, major depression is an umlsterm, treatment is an umlsterm, patients is an umlsterm, mood is an umlsterm, treatment is an umlsterm, patients is an umlsterm	DerNervenarzt.80690066.eng.abstr_task1	Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please typing these entity words according to sentence: patients, major depression, disorder, sleep deprivation, TSD, TSD, naps, night 's, methods, sleep, mood, male, patients, major depression, treatment, patients, mood, treatment, patients Options: umlsterm	[ "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .	[ "Approximately", "60", "%", "of", "patients", "with", "major", "depression", "disorder", "show", "a", "beneficial", "response", "to", "total", "sleep", "deprivation", "(", "TSD", ")", ",", "but", "the", "positive", "effect", "of", "TSD", "is", "short", ",", "and", "naps", "or", "the", "following", "night", "'s", "sleep", "destroy", "it", ".", "Various", "methods", "have", "been", "tried", "to", "stabilize", "the", "positive", "sleep", "-", "deprivation", "effect", ".", "A", "consecutive", "1-week", "advance", "in", "the", "sleep", "phase", "stabilized", "mood", "in", "more", "than", "50", "%", "of", "the", "sleep", "-", "deprivation", "responders", ".", "We", "examined", "40", "male", "patients", "with", "major", "depression", "who", "in", "addition", "to", "medical", "treatment", "took", "part", "in", "a", "phase", "advance", "study", "to", "prove", "possible", "synergistic", "effects", ".", "About", "60", "%", "of", "the", "patients", "showed", "positive", "mood", "stabilization", "after", "1-week", "of", "treatment", "when", "the", "patients", "were", "sleep", "-", "deprivation", "responders", ".", "These", "results", "support", "data", "from", "other", "groups", "." ]	[ "umlsterm" ]
patients, major depression, disorder, sleep deprivation, TSD, TSD, naps, night 's, methods, sleep, mood, male, patients, major depression, treatment, patients, mood, treatment, patients	DerNervenarzt.80690066.eng.abstr_task2	Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .	[ "Approximately", "60", "%", "of", "patients", "with", "major", "depression", "disorder", "show", "a", "beneficial", "response", "to", "total", "sleep", "deprivation", "(", "TSD", ")", ",", "but", "the", "positive", "effect", "of", "TSD", "is", "short", ",", "and", "naps", "or", "the", "following", "night", "'s", "sleep", "destroy", "it", ".", "Various", "methods", "have", "been", "tried", "to", "stabilize", "the", "positive", "sleep", "-", "deprivation", "effect", ".", "A", "consecutive", "1-week", "advance", "in", "the", "sleep", "phase", "stabilized", "mood", "in", "more", "than", "50", "%", "of", "the", "sleep", "-", "deprivation", "responders", ".", "We", "examined", "40", "male", "patients", "with", "major", "depression", "who", "in", "addition", "to", "medical", "treatment", "took", "part", "in", "a", "phase", "advance", "study", "to", "prove", "possible", "synergistic", "effects", ".", "About", "60", "%", "of", "the", "patients", "showed", "positive", "mood", "stabilization", "after", "1-week", "of", "treatment", "when", "the", "patients", "were", "sleep", "-", "deprivation", "responders", ".", "These", "results", "support", "data", "from", "other", "groups", "." ]	[ "umlsterm" ]
249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes is a participant	1296_task0	Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: participant	[ "O", "B-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "O" ]	Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .	[ "Recruited", "249", "adults", "from", "Washington", "State", "aged", "55", "to", "75", "with", "a", "doctor", "-", "confirmed", "diagnosis", "of", "osteoarthritis", "to", "participate", "in", "aquatic", "classes", "." ]	[ "participant", "intervention" ]
249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes is a participant	1296_task1	Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please typing these entity words according to sentence: 249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes Options: participant	[ "O", "B-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "O" ]	Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .	[ "Recruited", "249", "adults", "from", "Washington", "State", "aged", "55", "to", "75", "with", "a", "doctor", "-", "confirmed", "diagnosis", "of", "osteoarthritis", "to", "participate", "in", "aquatic", "classes", "." ]	[ "participant", "intervention" ]
249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes	1296_task2	Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please extract entity words from the input sentence	[ "O", "B-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "O" ]	Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .	[ "Recruited", "249", "adults", "from", "Washington", "State", "aged", "55", "to", "75", "with", "a", "doctor", "-", "confirmed", "diagnosis", "of", "osteoarthritis", "to", "participate", "in", "aquatic", "classes", "." ]	[ "participant", "intervention" ]
disease is an umlsterm, therapy is an umlsterm, head is an umlsterm, neck tumors is an umlsterm, radiotherapy is an umlsterm, patients is an umlsterm, tumors is an umlsterm, signs is an umlsterm, tumour is an umlsterm, assessment is an umlsterm, larynx is an umlsterm, laryngoscopy is an umlsterm, radiation is an umlsterm, laryngoscopy is an umlsterm, neck is an umlsterm, technique is an umlsterm, vocal cords is an umlsterm, -phonation is an umlsterm	DerRadiologe.80380122.eng.abstr_task0	Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O" ]	The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .	[ "The", "importance", "of", "spiral", "-", "CT", "is", "clinically", "accepted", "for", "diagnosing", "spreading", "disease", "and", "for", "making", "a", "decision", "about", "the", "therapy", "strategy", "for", "head", "and", "neck", "tumors", ".", "Its", "importance", "for", "follow", "-", "up", "after", "radiotherapy", "was", "examined", "in", "26", "patients", "with", "irradiated", "laryngeal", "tumors", ".", "Using", "spiral", "-", "CT", "multiple", "signs", "of", "alterations", "(", "n", "=", "98", ")", "can", "be", "diagnosed", ",", "which", "are", "not", "only", "important", "for", "tumour", "relapse", ",", "but", "also", "for", "assessment", ".", "Spiral", "-", "CT", "offers", "the", "possibility", "of", "achieviny", "various", "additional", "information", "about", "the", "larynx", "that", "cannot", "be", "obtained", "with", "laryngoscopy", ".", "In", "follow", "-", "up", "examinations", "after", "radiation", ",", "laryngoscopy", "and", "spiral", "-", "CT", "are", "recommended", "as", "an", "integrated", "neck", "examination", "using", "the", "breath", "-", "holding", "technique", "(", "separately", "reconstructed", ")", "and", "also", "as", "functional", "spiral", "-", "CT", "of", "the", "vocal", "cords", "in", "\"", "I", "\"", "-phonation", "." ]	[ "umlsterm" ]
disease is an umlsterm, therapy is an umlsterm, head is an umlsterm, neck tumors is an umlsterm, radiotherapy is an umlsterm, patients is an umlsterm, tumors is an umlsterm, signs is an umlsterm, tumour is an umlsterm, assessment is an umlsterm, larynx is an umlsterm, laryngoscopy is an umlsterm, radiation is an umlsterm, laryngoscopy is an umlsterm, neck is an umlsterm, technique is an umlsterm, vocal cords is an umlsterm, -phonation is an umlsterm	DerRadiologe.80380122.eng.abstr_task1	Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please typing these entity words according to sentence: disease, therapy, head, neck tumors, radiotherapy, patients, tumors, signs, tumour, assessment, larynx, laryngoscopy, radiation, laryngoscopy, neck, technique, vocal cords, -phonation Options: umlsterm	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O" ]	The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .	[ "The", "importance", "of", "spiral", "-", "CT", "is", "clinically", "accepted", "for", "diagnosing", "spreading", "disease", "and", "for", "making", "a", "decision", "about", "the", "therapy", "strategy", "for", "head", "and", "neck", "tumors", ".", "Its", "importance", "for", "follow", "-", "up", "after", "radiotherapy", "was", "examined", "in", "26", "patients", "with", "irradiated", "laryngeal", "tumors", ".", "Using", "spiral", "-", "CT", "multiple", "signs", "of", "alterations", "(", "n", "=", "98", ")", "can", "be", "diagnosed", ",", "which", "are", "not", "only", "important", "for", "tumour", "relapse", ",", "but", "also", "for", "assessment", ".", "Spiral", "-", "CT", "offers", "the", "possibility", "of", "achieviny", "various", "additional", "information", "about", "the", "larynx", "that", "cannot", "be", "obtained", "with", "laryngoscopy", ".", "In", "follow", "-", "up", "examinations", "after", "radiation", ",", "laryngoscopy", "and", "spiral", "-", "CT", "are", "recommended", "as", "an", "integrated", "neck", "examination", "using", "the", "breath", "-", "holding", "technique", "(", "separately", "reconstructed", ")", "and", "also", "as", "functional", "spiral", "-", "CT", "of", "the", "vocal", "cords", "in", "\"", "I", "\"", "-phonation", "." ]	[ "umlsterm" ]
disease, therapy, head, neck tumors, radiotherapy, patients, tumors, signs, tumour, assessment, larynx, laryngoscopy, radiation, laryngoscopy, neck, technique, vocal cords, -phonation	DerRadiologe.80380122.eng.abstr_task2	Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O" ]	The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .	[ "The", "importance", "of", "spiral", "-", "CT", "is", "clinically", "accepted", "for", "diagnosing", "spreading", "disease", "and", "for", "making", "a", "decision", "about", "the", "therapy", "strategy", "for", "head", "and", "neck", "tumors", ".", "Its", "importance", "for", "follow", "-", "up", "after", "radiotherapy", "was", "examined", "in", "26", "patients", "with", "irradiated", "laryngeal", "tumors", ".", "Using", "spiral", "-", "CT", "multiple", "signs", "of", "alterations", "(", "n", "=", "98", ")", "can", "be", "diagnosed", ",", "which", "are", "not", "only", "important", "for", "tumour", "relapse", ",", "but", "also", "for", "assessment", ".", "Spiral", "-", "CT", "offers", "the", "possibility", "of", "achieviny", "various", "additional", "information", "about", "the", "larynx", "that", "cannot", "be", "obtained", "with", "laryngoscopy", ".", "In", "follow", "-", "up", "examinations", "after", "radiation", ",", "laryngoscopy", "and", "spiral", "-", "CT", "are", "recommended", "as", "an", "integrated", "neck", "examination", "using", "the", "breath", "-", "holding", "technique", "(", "separately", "reconstructed", ")", "and", "also", "as", "functional", "spiral", "-", "CT", "of", "the", "vocal", "cords", "in", "\"", "I", "\"", "-phonation", "." ]	[ "umlsterm" ]
L - malic acid is a CHEMICAL	17203264_task0	Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: CHEMICAL	[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]	Fluorescent sensing layer for the determination of L-malic acid in wine.	[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]	[ "CHEMICAL", "GENE-N" ]
L - malic acid is a CHEMICAL	17203264_task1	Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please typing these entity words according to sentence: L - malic acid Options: CHEMICAL	[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]	Fluorescent sensing layer for the determination of L-malic acid in wine.	[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]	[ "CHEMICAL", "GENE-N" ]
L - malic acid	17203264_task2	Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]	Fluorescent sensing layer for the determination of L-malic acid in wine.	[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]	[ "CHEMICAL", "GENE-N" ]
Emergency Department ( ED ) is a Visit, Acute Bacterial Skin and Skin Structure Infections is a Measurement, ABSSSI is a Measurement, gram - positive is a Qualifier, infection is a Condition	NCT02961764_inc_task0	Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Condition, Measurement, Visit, Qualifier	[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]	Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.	[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]	[ "Measurement", "Visit", "Qualifier", "Condition" ]
Emergency Department ( ED ) is a Visit, Acute Bacterial Skin and Skin Structure Infections is a Measurement, ABSSSI is a Measurement, gram - positive is a Qualifier, infection is a Condition	NCT02961764_inc_task1	Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please typing these entity words according to sentence: Emergency Department ( ED ), Acute Bacterial Skin and Skin Structure Infections, ABSSSI, gram - positive, infection Options: Condition, Measurement, Visit, Qualifier	[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]	Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.	[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]	[ "Measurement", "Visit", "Qualifier", "Condition" ]
Emergency Department ( ED ), Acute Bacterial Skin and Skin Structure Infections, ABSSSI, gram - positive, infection	NCT02961764_inc_task2	Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]	Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.	[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]	[ "Measurement", "Visit", "Qualifier", "Condition" ]
collagenase-1 is a protein_molecule, differentiated monocyte - like ( U937 ) cells is a cell_line, AP-1 is a protein_molecule, upstream C / EBP - beta site is a DNA_domain_or_region	62476_task0	Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: DNA_domain_or_region, cell_line, protein_molecule	[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.	[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]	[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]
collagenase-1 is a protein_molecule, differentiated monocyte - like ( U937 ) cells is a cell_line, AP-1 is a protein_molecule, upstream C / EBP - beta site is a DNA_domain_or_region	62476_task1	Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please typing these entity words according to sentence: collagenase-1, differentiated monocyte - like ( U937 ) cells, AP-1, upstream C / EBP - beta site Options: DNA_domain_or_region, cell_line, protein_molecule	[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.	[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]	[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]
collagenase-1, differentiated monocyte - like ( U937 ) cells, AP-1, upstream C / EBP - beta site	62476_task2	Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]	Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.	[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]	[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]
argón is a NORMALIZABLES, triamcinolona is a NORMALIZABLES, fluoresceína sódica is a NORMALIZABLES	213_task0	Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: NORMALIZABLES	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "I-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.	[ "Se", "estudió", "en", "nuestra", "consulta", "a", "un", "paciente", "varón", "de", "57", "años", "con", "antecedentes", "de", "diabetes", "mellitus", "tipo", "II", ",", "hipertensión", "y", "cardiopatía", "isquémica", ",", "por", "presentar", "retinopatía", "diabética", "proliferativa", ".", "Su", "agudeza", "visual", "era", "de", "20/50", "en", "el", "ojo", "derecho", "(", "OD", ")", "y", "de", "20/25", "en", "el", "izquierdo", "(", "OI", ")", ".", "Previamente", "había", "sido", "tratado", "con", "panretinofotocoagulación", "con", "láser", "argón", "en", "ambos", "ojos", ",", "así", "como", "con", "vitrectomía", "pars", "plana", "y", "pelado", "de", "membrana", "limitante", "interna", "con", "inyección", "de", "triamcinolona", "intravítrea", "en", "OD", "debido", "a", "una", "hemorragia", "vítrea", "y", "edema", "macular", "difuso", "crónico", ".", "No", "se", "observaban", "membranas", "neovasculares", "residuales", "en", "el", "examen", "del", "fondo", "de", "ojo", ",", "pero", "si", "microaneurismas", "y", "hemorragias", "en", "el", "polo", "posterior", "de", "ambos", "ojos", ".", "En", "el", "ojo", "izquierdo", ",", "se", "observaban", "algunos", "AMIR", "en", "la", "zona", "temporal", "de", "la", "macula", ".", "\n", "Se", "realizó", "una", "angiografía", "fluoreseceínica", "usando", "5", "ml", "de", "fluoresceína", "sódica", "al", "10", "%", ".", "Se", "observaron", "áreas", "isquémicas", "ecuatoriales", "y", "en", "el", "ojo", "izquierdo", "edema", "macular", "difuso", "y", "la", "AMIR", ",", "pero", "no", "se", "observaron", "membranas", "neovasculares", ".", "En", "este", "ojo", "y", "después", "de", "8", "minutos", "de", "angiograma", ",", "ocurrió", "un", "sangrado", "activo", "de", "la", "AMIR", ".", "El", "movimiento", "de", "los", "ojos", "dejó", "diferentes", "trazos", "de", "sangre", "en", "la", "cavidad", "vítrea", ".", "El", "sangrado", "fue", "breve", "y", "autolimitado", ",", "sin", "síntomas", "inicialmente", ".", "Poco", "después", "el", "paciente", "empezó", "a", "notar", "miodesospsias", ".", "Dos", "semanas", "más", "tarde", ",", "la", "hemorragia", "vítrea", "se", "resolvió", "sin", "consecuencias", ".", "\n\n" ]	[ "NORMALIZABLES" ]
argón is a NORMALIZABLES, triamcinolona is a NORMALIZABLES, fluoresceína sódica is a NORMALIZABLES	213_task1	Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please typing these entity words according to sentence: argón, triamcinolona, fluoresceína sódica Options: NORMALIZABLES	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "I-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.	[ "Se", "estudió", "en", "nuestra", "consulta", "a", "un", "paciente", "varón", "de", "57", "años", "con", "antecedentes", "de", "diabetes", "mellitus", "tipo", "II", ",", "hipertensión", "y", "cardiopatía", "isquémica", ",", "por", "presentar", "retinopatía", "diabética", "proliferativa", ".", "Su", "agudeza", "visual", "era", "de", "20/50", "en", "el", "ojo", "derecho", "(", "OD", ")", "y", "de", "20/25", "en", "el", "izquierdo", "(", "OI", ")", ".", "Previamente", "había", "sido", "tratado", "con", "panretinofotocoagulación", "con", "láser", "argón", "en", "ambos", "ojos", ",", "así", "como", "con", "vitrectomía", "pars", "plana", "y", "pelado", "de", "membrana", "limitante", "interna", "con", "inyección", "de", "triamcinolona", "intravítrea", "en", "OD", "debido", "a", "una", "hemorragia", "vítrea", "y", "edema", "macular", "difuso", "crónico", ".", "No", "se", "observaban", "membranas", "neovasculares", "residuales", "en", "el", "examen", "del", "fondo", "de", "ojo", ",", "pero", "si", "microaneurismas", "y", "hemorragias", "en", "el", "polo", "posterior", "de", "ambos", "ojos", ".", "En", "el", "ojo", "izquierdo", ",", "se", "observaban", "algunos", "AMIR", "en", "la", "zona", "temporal", "de", "la", "macula", ".", "\n", "Se", "realizó", "una", "angiografía", "fluoreseceínica", "usando", "5", "ml", "de", "fluoresceína", "sódica", "al", "10", "%", ".", "Se", "observaron", "áreas", "isquémicas", "ecuatoriales", "y", "en", "el", "ojo", "izquierdo", "edema", "macular", "difuso", "y", "la", "AMIR", ",", "pero", "no", "se", "observaron", "membranas", "neovasculares", ".", "En", "este", "ojo", "y", "después", "de", "8", "minutos", "de", "angiograma", ",", "ocurrió", "un", "sangrado", "activo", "de", "la", "AMIR", ".", "El", "movimiento", "de", "los", "ojos", "dejó", "diferentes", "trazos", "de", "sangre", "en", "la", "cavidad", "vítrea", ".", "El", "sangrado", "fue", "breve", "y", "autolimitado", ",", "sin", "síntomas", "inicialmente", ".", "Poco", "después", "el", "paciente", "empezó", "a", "notar", "miodesospsias", ".", "Dos", "semanas", "más", "tarde", ",", "la", "hemorragia", "vítrea", "se", "resolvió", "sin", "consecuencias", ".", "\n\n" ]	[ "NORMALIZABLES" ]
argón, triamcinolona, fluoresceína sódica	213_task2	Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please extract entity words from the input sentence	[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "I-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]	Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.	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radius fracture is an umlsterm, human is an umlsterm, injury is an umlsterm, woman is an umlsterm, post menopause is an umlsterm, osteoporosis is an umlsterm, calcium is an umlsterm, balance is an umlsterm, radius fracture is an umlsterm, classification is an umlsterm, treatment is an umlsterm, secondary is an umlsterm, exact is an umlsterm, K - wire is an umlsterm, screw is an umlsterm, forms is an umlsterm, posttraumatical is an umlsterm, joint is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, radius is an umlsterm, exact is an umlsterm, therapy is an umlsterm, University is an umlsterm, Berlin is an umlsterm, patients is an umlsterm, radius fractures is an umlsterm, dorsaly is an umlsterm, plate is an umlsterm, fractures is an umlsterm, bicortal is an umlsterm, bone is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, arthrosis is an umlsterm, X - ray is an umlsterm, evaluation is an umlsterm, assessment is an umlsterm	DerOrthopaede.90280853.eng.abstr_task0	Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O" ]	The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .	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radius fracture is an umlsterm, human is an umlsterm, injury is an umlsterm, woman is an umlsterm, post menopause is an umlsterm, osteoporosis is an umlsterm, calcium is an umlsterm, balance is an umlsterm, radius fracture is an umlsterm, classification is an umlsterm, treatment is an umlsterm, secondary is an umlsterm, exact is an umlsterm, K - wire is an umlsterm, screw is an umlsterm, forms is an umlsterm, posttraumatical is an umlsterm, joint is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, radius is an umlsterm, exact is an umlsterm, therapy is an umlsterm, University is an umlsterm, Berlin is an umlsterm, patients is an umlsterm, radius fractures is an umlsterm, dorsaly is an umlsterm, plate is an umlsterm, fractures is an umlsterm, bicortal is an umlsterm, bone is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, arthrosis is an umlsterm, X - ray is an umlsterm, evaluation is an umlsterm, assessment is an umlsterm	DerOrthopaede.90280853.eng.abstr_task1	Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please typing these entity words according to sentence: radius fracture, human, injury, woman, post menopause, osteoporosis, calcium, balance, radius fracture, classification, treatment, secondary, exact, K - wire, screw, forms, posttraumatical, joint, secondary, dislocation, radius, exact, therapy, University, Berlin, patients, radius fractures, dorsaly, plate, fractures, bicortal, bone, secondary, dislocation, arthrosis, X - ray, evaluation, assessment Options: umlsterm	[ "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O" ]	The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .	[ "The", "distal", "radius", "fracture", "is", "the", "most", "common", "human", "skeletal", "injury", ".", "Predominantly", "woman", "in", "the", "6th", "to", "7th", "decade", "are", "found", ".", "There", "is", "a", "high", "correlation", "to", "the", "post", "menopause", "high", "turn", "over", "osteoporosis", "and", "its", "negative", "calcium", "balance", ".", "Due", "to", "the", "various", "multifactoral", "radius", "fracture", "combinations", "is", "a", "detailed", "classification", "with", "its", "correlated", "treatment", "important", ".", "The", "operative", "intervention", "in", "the", "past", "played", "a", "secondary", "roll", ".", "The", "newest", "concepts", "demand", "an", "exact", "reconstruction", "of", "the", "articulating", "surfaces", "through", "closed", "reposition", "and", "K", "-", "wire", "support", ",", "screw", "osteosynthesis", ",", "external", "fixation", "and", "its", "combinated", "forms", ".", "The", "posttraumatical", "joint", "changes", "with", "secondary", "palmar", "and", "dorsal", "dislocation", "of", "the", "radius", "base", "after", "reduction", "caused", "the", "exact", "therapy", "scheme", "with", "respect", "to", "the", "AO", "-", "classification", "to", "be", "developed", ".", "In", "the", "clinic", "and", "policlinic", "Oskar", "-", "Helene", "-", "Heim", "of", "the", "Free", "University", "in", "Berlin", "213", "patients", "were", "surgicly", "treated", "on", "distal", "radius", "fractures", "either", "from", "volar", "or", "dorsaly", "with", "a", "plate", "osteosynthesis", "between", "1988", "-", "1998", ".", "In", "cases", "of", "multidirectionional", "fractures", "with", "compression", "of", "the", "articular", "surfaces", "we", "combined", "a", "bicortal", "bone", "block", "or", "spongiosa", "to", "support", "and", "to", "avoid", "the", "secondary", "dislocation", "and", "thus", "arthrosis", ".", "The", "study", "was", "devided", "in", "three", "sections", ",", "beginning", "with", "the", "clinical", "inspection", ".", "Further", "followed", "the", "X", "-", "ray", "evaluation", "and", "the", "assessment", "of", "the", "DASH", "-", "scores", "." ]	[ "umlsterm" ]
radius fracture, human, injury, woman, post menopause, osteoporosis, calcium, balance, radius fracture, classification, treatment, secondary, exact, K - wire, screw, forms, posttraumatical, joint, secondary, dislocation, radius, exact, therapy, University, Berlin, patients, radius fractures, dorsaly, plate, fractures, bicortal, bone, secondary, dislocation, arthrosis, X - ray, evaluation, assessment	DerOrthopaede.90280853.eng.abstr_task2	Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please extract entity words from the input sentence	[ "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O" ]	The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .	[ "The", "distal", "radius", "fracture", "is", "the", "most", "common", "human", "skeletal", "injury", ".", "Predominantly", "woman", "in", "the", "6th", "to", "7th", "decade", "are", "found", ".", "There", "is", "a", "high", "correlation", "to", "the", "post", "menopause", "high", "turn", "over", "osteoporosis", "and", "its", "negative", "calcium", "balance", ".", "Due", "to", "the", "various", "multifactoral", "radius", "fracture", "combinations", "is", "a", "detailed", "classification", "with", "its", "correlated", "treatment", "important", ".", "The", "operative", "intervention", "in", "the", "past", "played", "a", "secondary", "roll", ".", "The", "newest", "concepts", "demand", "an", "exact", "reconstruction", "of", "the", "articulating", "surfaces", "through", "closed", "reposition", "and", "K", "-", "wire", "support", ",", "screw", "osteosynthesis", ",", "external", "fixation", "and", "its", "combinated", "forms", ".", "The", "posttraumatical", "joint", "changes", "with", "secondary", "palmar", "and", "dorsal", "dislocation", "of", "the", "radius", "base", "after", "reduction", "caused", "the", "exact", "therapy", "scheme", "with", "respect", "to", "the", "AO", "-", "classification", "to", "be", "developed", ".", "In", "the", "clinic", "and", "policlinic", "Oskar", "-", "Helene", "-", "Heim", "of", "the", "Free", "University", "in", "Berlin", "213", "patients", "were", "surgicly", "treated", "on", "distal", "radius", "fractures", "either", "from", "volar", "or", "dorsaly", "with", "a", "plate", "osteosynthesis", "between", "1988", "-", "1998", ".", "In", "cases", "of", "multidirectionional", "fractures", "with", "compression", "of", "the", "articular", "surfaces", "we", "combined", "a", "bicortal", "bone", "block", "or", "spongiosa", "to", "support", "and", "to", "avoid", "the", "secondary", "dislocation", "and", "thus", "arthrosis", ".", "The", "study", "was", "devided", "in", "three", "sections", ",", "beginning", "with", "the", "clinical", "inspection", ".", "Further", "followed", "the", "X", "-", "ray", "evaluation", "and", "the", "assessment", "of", "the", "DASH", "-", "scores", "." ]	[ "umlsterm" ]
catheter is an umlsterm, therapy is an umlsterm, coronary artery disease is an umlsterm, techniques is an umlsterm, patients is an umlsterm, balloon angioplasty is an umlsterm, tissue is an umlsterm, stent is an umlsterm, implantation is an umlsterm, techniques is an umlsterm, prevention is an umlsterm, pharmacologic is an umlsterm, radiotherapeutic is an umlsterm, future is an umlsterm	ZfuerKardiologie.8087s052.eng.abstr_task0	Sentence: The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm	[ "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O" ]	The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis .	[ "The", "success", "of", "interventional", "catheter", "based", "therapy", "of", "coronary", "artery", "disease", "is", "still", "limited", "by", "a", "high", "rate", "of", "chronic", "restenosis", ".", "Using", "alternative", "mechanical", "techniques", ",", "there", "is", "increasing", "evidence", "that", "restenosis", "can", "be", "prevented", "in", "certain", "subsets", "of", "patients", "by", "optimized", "balloon", "angioplasty", ",", "DCA", "and", "stenting", "as", "well", "as", "by", "the", "combined", "approach", "of", "primary", "tissue", "removal", "with", "adjunctive", "stent", "implantation", ".", "This", "article", "summarizes", "the", "mechanical", "techniques", "of", "restenosis", "prevention", "or", "reduction", "that", "have", "been", "documented", "in", "controlled", "trials", ".", "Additional", "pharmacologic", "interventions", "and", "possibly", "genetic", "and", "/", "or", "radiotherapeutic", "approaches", "will", "be", "highly", "important", "for", "future", "reduction", "of", "restenosis", "." ]	[ "umlsterm" ]
catheter is an umlsterm, therapy is an umlsterm, coronary artery disease is an umlsterm, techniques is an umlsterm, patients is an umlsterm, balloon angioplasty is an umlsterm, tissue is an umlsterm, stent is an umlsterm, implantation is an umlsterm, techniques is an umlsterm, prevention is an umlsterm, pharmacologic is an umlsterm, radiotherapeutic is an umlsterm, future is an umlsterm	ZfuerKardiologie.8087s052.eng.abstr_task1	Sentence: The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis . Instructions: please typing these entity words according to sentence: catheter, therapy, coronary artery disease, techniques, patients, balloon angioplasty, tissue, stent, implantation, techniques, prevention, pharmacologic, radiotherapeutic, future Options: umlsterm	[ "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O" ]	The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis .	[ "The", "success", "of", "interventional", "catheter", "based", "therapy", "of", "coronary", "artery", "disease", "is", "still", "limited", "by", "a", "high", "rate", "of", "chronic", "restenosis", ".", "Using", "alternative", "mechanical", "techniques", ",", "there", "is", "increasing", "evidence", "that", "restenosis", "can", "be", "prevented", "in", "certain", "subsets", "of", "patients", "by", "optimized", "balloon", "angioplasty", ",", "DCA", "and", "stenting", "as", "well", "as", "by", "the", "combined", "approach", "of", "primary", "tissue", "removal", "with", "adjunctive", "stent", "implantation", ".", "This", "article", "summarizes", "the", "mechanical", "techniques", "of", "restenosis", "prevention", "or", "reduction", "that", "have", "been", "documented", "in", "controlled", "trials", ".", "Additional", "pharmacologic", "interventions", "and", "possibly", "genetic", "and", "/", "or", "radiotherapeutic", "approaches", "will", "be", "highly", "important", "for", "future", "reduction", "of", "restenosis", "." ]	[ "umlsterm" ]

ghrelin is a protein, serine is a compound

DS.d1801_task1

Sentence: The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size. Instructions: please typing these entity words according to sentence: ghrelin, serine Options: compound, protein

[ "O", "O", "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size.

[ "The", "acyl", "ghrelin", "peptide", "features", "a", "unique", "post", "-", "translational", "modification", "of", "O", "-", "n", "-", "octanoylation", "at", "serine", "3", ",", "and", "is", "the", "only", "gastrointestinal", "signal", "that", "increases", "meal", "size", "." ]

[ "protein", "compound" ]

ghrelin, serine

DS.d1801_task2

Sentence: The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size. Instructions: please extract entity words from the input sentence

[ "O", "O", "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

The acyl ghrelin peptide features a unique post-translational modification of O-n-octanoylation at serine 3, and is the only gastrointestinal signal that increases meal size.

[ "The", "acyl", "ghrelin", "peptide", "features", "a", "unique", "post", "-", "translational", "modification", "of", "O", "-", "n", "-", "octanoylation", "at", "serine", "3", ",", "and", "is", "the", "only", "gastrointestinal", "signal", "that", "increases", "meal", "size", "." ]

[ "protein", "compound" ]

tissue specimens is a Tissue, fragment is a Cancer, tumour is a Cancer, endometrial biopsy is a Tissue, fragment is a Cancer, tissue fragments is a Tissue, specimens is a Tissue

PMID-10823148_task0

Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Tissue, Cancer

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]

Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.

[ "Application", "of", "microsatellite", "PCR", "techniques", "in", "the", "identification", "of", "mixed", "up", "tissue", "specimens", "in", "surgical", "pathology", ".", "\n", "A", "fragment", "of", "tumour", "was", "erroneously", "mixed", "up", "with", "an", "endometrial", "biopsy", ".", "Micro", "-", "satellite", "polymerase", "chain", "reaction", "(", "PCR", ")", "clearly", "demonstrated", "the", "extraneous", "nature", "of", "the", "fragment", ".", "Micro", "-", "satellite", "PCR", "may", "be", "useful", "for", "the", "identification", "of", "mis", "-", "labelled", "or", "mismatched", "tissue", "fragments", "in", "surgical", "pathology", "specimens", ".", "\n" ]

[ "Tissue", "Cancer" ]

tissue specimens is a Tissue, fragment is a Cancer, tumour is a Cancer, endometrial biopsy is a Tissue, fragment is a Cancer, tissue fragments is a Tissue, specimens is a Tissue

PMID-10823148_task1

Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please typing these entity words according to sentence: tissue specimens, fragment, tumour, endometrial biopsy, fragment, tissue fragments, specimens Options: Tissue, Cancer

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]

Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.

[ "Application", "of", "microsatellite", "PCR", "techniques", "in", "the", "identification", "of", "mixed", "up", "tissue", "specimens", "in", "surgical", "pathology", ".", "\n", "A", "fragment", "of", "tumour", "was", "erroneously", "mixed", "up", "with", "an", "endometrial", "biopsy", ".", "Micro", "-", "satellite", "polymerase", "chain", "reaction", "(", "PCR", ")", "clearly", "demonstrated", "the", "extraneous", "nature", "of", "the", "fragment", ".", "Micro", "-", "satellite", "PCR", "may", "be", "useful", "for", "the", "identification", "of", "mis", "-", "labelled", "or", "mismatched", "tissue", "fragments", "in", "surgical", "pathology", "specimens", ".", "\n" ]

[ "Tissue", "Cancer" ]

tissue specimens, fragment, tumour, endometrial biopsy, fragment, tissue fragments, specimens

PMID-10823148_task2

Sentence: Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Cancer", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Tissue", "I-Tissue", "O", "O", "O", "B-Tissue", "O", "O" ]

Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology. A fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction (PCR) clearly demonstrated the extraneous nature of the fragment. Micro-satellite PCR may be useful for the identification of mis-labelled or mismatched tissue fragments in surgical pathology specimens.

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[ "Tissue", "Cancer" ]

Fc gamma RI is a Protein, Fc gamma RII is a Protein, TNF - alpha is a Protein, IL-1 beta is a Protein, TNF - alpha is a Protein

558_task0

Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Protein

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Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.

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[ "Protein" ]

Fc gamma RI is a Protein, Fc gamma RII is a Protein, TNF - alpha is a Protein, IL-1 beta is a Protein, TNF - alpha is a Protein

558_task1

Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please typing these entity words according to sentence: Fc gamma RI, Fc gamma RII, TNF - alpha, IL-1 beta, TNF - alpha Options: Protein

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Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.

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[ "Protein" ]

Fc gamma RI, Fc gamma RII, TNF - alpha, IL-1 beta, TNF - alpha

558_task2

Sentence: Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes. Instructions: please extract entity words from the input sentence

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Cross-linking of Fc gamma receptors activates HIV-1 long terminal repeat-driven transcription in human monocytes. Elevation of the levels of circulating immune complexes frequently accompanies HIV-1 infection and is a prognostic indicator of clinical progression from asymptomatic infection to AIDS. Here we report that cross-linking of Fc gamma RI or Fc gamma RII by adherent human IgG or by specific anti-Fc gamma R mAb activates HIV-1 gene expression in the human monocytic cell line BF24 and increased HIV RNA expression in monocytes from HIV infected patients as assayed by reverse transcription-PCR. In THP-1 cells, Fc gamma R cross-linking induced NF-kappa B, which is known to bind to the regulatory region of the long terminal repeat (LTR) of HIV-1 and to activate HIV-1 transcription. Anti-TNF-alpha antibody but not anti-IL-1 beta antibody strongly inhibited both the induction of HIV-1-LTR-driven transcription and the induction of NF-kappa B by Fc gamma R cross-linking. These results indicate that Fc gamma R can mediate a TNF-alpha-dependent induction of HIV-1 gene transcription and suggest that immune complexes may contribute to the pathophysiology of HIV-1 infection by augmenting viral replication in monocytes.

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[ "Protein" ]

syndromes is an umlsterm, PNS is an umlsterm, disorders is an umlsterm, nervous system is an umlsterm, tumor is an umlsterm, treatment is an umlsterm, PNS is an umlsterm, association is an umlsterm, lung is an umlsterm, breast is an umlsterm, carcinomas is an umlsterm, PNS is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, time is an umlsterm, value is an umlsterm, carcinoma is an umlsterm, PNS is an umlsterm, anatomical is an umlsterm, antibodies is an umlsterm, syndromes is an umlsterm, encephalitis is an umlsterm, Opsoclonus - Myoclonus syndrome is an umlsterm, Stiff - man syndrome is an umlsterm, neuromyotonia is an umlsterm, amaurosis is an umlsterm, autoantibodies is an umlsterm, neoplasm is an umlsterm, autoantibodies is an umlsterm, antibodies is an umlsterm, calcium channels is an umlsterm, Lambert - Eaton myasthenic syndrome is an umlsterm, potassium channels is an umlsterm, neuromyotonia is an umlsterm, recoverin is an umlsterm, cancer is an umlsterm, retinopathy is an umlsterm, symptoms is an umlsterm, PNS is an umlsterm, tumors is an umlsterm, antibodies is an umlsterm, diagnosis is an umlsterm, pathogenesis is an umlsterm, PNS is an umlsterm

DerNervenarzt.90700688.eng.abstr_task0

Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .

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[ "umlsterm" ]

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DerNervenarzt.90700688.eng.abstr_task1

Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please typing these entity words according to sentence: syndromes, PNS, disorders, nervous system, tumor, treatment, PNS, association, lung, breast, carcinomas, PNS, Lambert - Eaton myasthenic syndrome, time, value, carcinoma, PNS, anatomical, antibodies, syndromes, encephalitis, Opsoclonus - Myoclonus syndrome, Stiff - man syndrome, neuromyotonia, amaurosis, autoantibodies, neoplasm, autoantibodies, antibodies, calcium channels, Lambert - Eaton myasthenic syndrome, potassium channels, neuromyotonia, recoverin, cancer, retinopathy, symptoms, PNS, tumors, antibodies, diagnosis, pathogenesis, PNS Options: umlsterm

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Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .

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[ "umlsterm" ]

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DerNervenarzt.90700688.eng.abstr_task2

Sentence: Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS . Instructions: please extract entity words from the input sentence

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Paraneoplastic neurologic syndromes ( PNS ) are rare disorders of the nervous system that cannot be ascribed to metatastases or to destruction of vital systemic organs by the tumor or its treatment . Most frequently , PNS occur in association with small-cell lung , breast or ovarian carcinomas . The most frequent PNS is Lambert-Eaton myasthenic syndrome , which at the same time has the highest predictive value concerning an underlying carcinoma . PNS have been classified mostly under anatomical aspects but now are increasingly categorized according to specific antibodies . In certain neurologic syndromes ( sensible and autonomic neuropathy , cerebellitis , limbic encephalitis , Opsoclonus-Myoclonus syndrome , Stiff-man syndrome , neuromyotonia , subacute amaurosis ) specific autoantibodies are highly predictive for a neoplasm . Pathogenic relevance of these autoantibodies has been demonstrated only for antibodies against ( 1 ) voltage gated calcium channels ( VGCC ) in Lambert-Eaton myasthenic syndrome , ( 2 ) voltage gated potassium channels ( VGKC ) in neuromyotonia , and ( 3 ) recoverin in cancer associated retinopathy . The present article deals with the neurological symptoms of PNS , associated tumors , and the relevance of specific antibodies for the diagnosis and pathogenesis of PNS .

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[ "umlsterm" ]

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DerChirurg.00710877.eng.abstr_task0

Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .

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DerChirurg.00710877.eng.abstr_task1

Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please typing these entity words according to sentence: Abstract, incidence, malignant neoplasms, pleura, pericardium, peritoneum, Germany, asbestos, Germany, mesotheliomas, Mesothelioma, Registry, asbestos, occupational exposure, associations, mesotheliomas, Mesothelioma, Registry, mesotheliomas, etiology, pathogenesis, diagnostic, procedures, standards, genetic defects, mesothelioma, malignant, mesotheliomas, genetic alterations, diagnosis, therapeutic, biopsy, Surgery, role, therapy, malignant tumors, membranes, diagnosis, tumor, stages Options: umlsterm

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Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .

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[ "umlsterm" ]

Abstract, incidence, malignant neoplasms, pleura, pericardium, peritoneum, Germany, asbestos, Germany, mesotheliomas, Mesothelioma, Registry, asbestos, occupational exposure, associations, mesotheliomas, Mesothelioma, Registry, mesotheliomas, etiology, pathogenesis, diagnostic, procedures, standards, genetic defects, mesothelioma, malignant, mesotheliomas, genetic alterations, diagnosis, therapeutic, biopsy, Surgery, role, therapy, malignant tumors, membranes, diagnosis, tumor, stages

DerChirurg.00710877.eng.abstr_task2

Sentence: Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages . Instructions: please extract entity words from the input sentence

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Abstract . The incidence of primary malignant neoplasms of the pleura , the pericardium and the peritoneum in Germany has been rising since about the mid-1980 s. A continuing rise is expected until about 2020 , predominantly due to the peak of asbestos processing in Germany between 1965 and 1980. About 90 % of the mesotheliomas stored in the files of the German Mesothelioma Registry in Bochum are asbestos related and therefore possibly due to occupational exposure that may be compensated by the professional associations . More than 500 mesotheliomas annually can be diagnosed in the German Mesothelioma Registry . In this first part of the series on mesotheliomas , current concepts on etiology and pathogenesis as well as diagnostic procedures and standards are discussed . At the present , specific chromosomal or genetic defects that constantly give rise to a mesothelioma are not known . The initiation and progression of malignant mesotheliomas is a highly complex mechanism that is based on individual genetic alterations . A reliable diagnosis is the basis for therapeutic , prognostic and medicolegal conseques ; in general , it can be achieved by thoracoscopic inspection with selected biopsy . Surgery may gain a more important role in the therapy of malignant tumors of serosal membranes not only in palliative , but also in potential curative approaches if the diagnosis can be made at earlier tumor stages .

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[ "umlsterm" ]

5-(hydroxy)methylcytosine is a CHEMICAL

23434322_task0

Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: CHEMICAL

[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

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[ "CHEMICAL", "GENE-Y" ]

5-(hydroxy)methylcytosine is a CHEMICAL

23434322_task1

Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please typing these entity words according to sentence: 5-(hydroxy)methylcytosine Options: CHEMICAL

[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

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[ "CHEMICAL", "GENE-Y" ]

5-(hydroxy)methylcytosine

23434322_task2

Sentence: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "B-CHEMICAL", "O", "O", "O", "O", "O" ]

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

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[ "CHEMICAL", "GENE-Y" ]

Fruchtwasser is an umlsterm, Lebens- is an umlsterm, Morbiditaet is an umlsterm, Mortalitaet is an umlsterm, Schwangerschaften is an umlsterm, Therapie is an umlsterm, Behandlung is an umlsterm, Amniondrainage is an umlsterm, Indometacin is an umlsterm, Sulindac is an umlsterm, Urinproduktion is an umlsterm, Druckes is an umlsterm, Amniondrainage is an umlsterm, Fruchtwasservermehrung is an umlsterm, Therapie is an umlsterm, Therapie is an umlsterm, Fruchtwasservermehrung is an umlsterm, Komplikationen is an umlsterm

DerGynaekologe.90320823.ger.abstr_task0

Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . "

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[ "umlsterm" ]

Fruchtwasser is an umlsterm, Lebens- is an umlsterm, Morbiditaet is an umlsterm, Mortalitaet is an umlsterm, Schwangerschaften is an umlsterm, Therapie is an umlsterm, Behandlung is an umlsterm, Amniondrainage is an umlsterm, Indometacin is an umlsterm, Sulindac is an umlsterm, Urinproduktion is an umlsterm, Druckes is an umlsterm, Amniondrainage is an umlsterm, Fruchtwasservermehrung is an umlsterm, Therapie is an umlsterm, Therapie is an umlsterm, Fruchtwasservermehrung is an umlsterm, Komplikationen is an umlsterm

DerGynaekologe.90320823.ger.abstr_task1

Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please typing these entity words according to sentence: Fruchtwasser, Lebens-, Morbiditaet, Mortalitaet, Schwangerschaften, Therapie, Behandlung, Amniondrainage, Indometacin, Sulindac, Urinproduktion, Druckes, Amniondrainage, Fruchtwasservermehrung, Therapie, Therapie, Fruchtwasservermehrung, Komplikationen Options: umlsterm

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Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . "

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[ "umlsterm" ]

Fruchtwasser, Lebens-, Morbiditaet, Mortalitaet, Schwangerschaften, Therapie, Behandlung, Amniondrainage, Indometacin, Sulindac, Urinproduktion, Druckes, Amniondrainage, Fruchtwasservermehrung, Therapie, Therapie, Fruchtwasservermehrung, Komplikationen

DerGynaekologe.90320823.ger.abstr_task2

Sentence: Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . " Instructions: please extract entity words from the input sentence

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Fruchtwasser ist ein essentieller Lebens- und Entwicklungsfaktor in utero . Bei Abweichungen vom Normvolumen ist mit einer erhoehten perinatalen Morbiditaet und Mortalitaet zu rechnen ; 0,2-1,6 % der Schwangerschaften sind mit einer vermehrten Fruchtwassermenge belastet . Die haeufigste Indikation zur Therapie ist ein fetofetales Transfusionssyndrom bei monochorialen Mehrlingen . Die Behandlung des Polyhydramnions basiert auf der Beseitigung der ursaechlichen Stoerung oder der symptomatischen Korrektur durch Amniondrainage . Die medikamentoese Reduktion des polyurischen Polyhydramnions ist durch Zyklooxygenasehemmer moeglich . Indometacin Sulindac oder Nimesulide , fuehren ueber die Drosselung der kindlichen Urinproduktion zum Behandlungserfolg . Rasche Entlastung des erhoehten intrauterinen Druckes eroeffnet die grossvolumige Amniondrainage . Bei weitem nicht jede Fruchtwasservermehrung bedarf der Therapie . Milde Formen profitieren von expektativem Vorgehen . Der grundsaetzliche Ansatz der direkten oder indirekten Therapie einer Fruchtwasservermehrung zielt somit nicht auf die Korrektur des Polyhydramnions an sich , sondern vielmehr auf die Praevention seiner Komplikationen . Die Tragzeitverlaengerung und/oder die Verringerung der maternalen Verdraengungssymptome verbessern den fetal outcome " . "

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[ "umlsterm" ]

retrospective study is an umlsterm, medical records is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, antibiotic prophylaxis is an umlsterm, risk of is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, injuries is an umlsterm, occurrence is an umlsterm, meningitis is an umlsterm, use is an umlsterm, antibiotic is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, findings is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, prophylactic is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, antibiotic is an umlsterm, therapy is an umlsterm, symptoms is an umlsterm, meningitis is an umlsterm

HNO.70450448.eng.abstr_task0

Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .

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[ "umlsterm" ]

retrospective study is an umlsterm, medical records is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, antibiotic prophylaxis is an umlsterm, risk of is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, injuries is an umlsterm, occurrence is an umlsterm, meningitis is an umlsterm, use is an umlsterm, antibiotic is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, meningitis is an umlsterm, patients is an umlsterm, antibiotics is an umlsterm, meningitis is an umlsterm, findings is an umlsterm, patients is an umlsterm, skull base is an umlsterm, fractures is an umlsterm, prophylactic is an umlsterm, antibiotics is an umlsterm, patients is an umlsterm, antibiotic is an umlsterm, therapy is an umlsterm, symptoms is an umlsterm, meningitis is an umlsterm

HNO.70450448.eng.abstr_task1

Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please typing these entity words according to sentence: retrospective study, medical records, patients, skull base, fractures, antibiotic prophylaxis, risk of, meningitis, patients, antibiotics, meningitis, patients, antibiotics, meningitis, skull base, fractures, injuries, occurrence, meningitis, use, antibiotic, patients, antibiotics, patients, meningitis, patients, antibiotics, meningitis, findings, patients, skull base, fractures, prophylactic, antibiotics, patients, antibiotic, therapy, symptoms, meningitis Options: umlsterm

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A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .

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[ "umlsterm" ]

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HNO.70450448.eng.abstr_task2

Sentence: A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis . Instructions: please extract entity words from the input sentence

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A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( " simple " ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis .

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[ "umlsterm" ]

protein kinase C inhibitors is an other_name, fibronectin is a protein_molecule, interleukin - beta gene is a DNA_domain_or_region, human monocytic cells is a cell_type

69896_task0

Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: cell_type, DNA_domain_or_region, protein_molecule, other_name

[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]

Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.

[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]

[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]

protein kinase C inhibitors is an other_name, fibronectin is a protein_molecule, interleukin - beta gene is a DNA_domain_or_region, human monocytic cells is a cell_type

69896_task1

Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please typing these entity words according to sentence: protein kinase C inhibitors, fibronectin, interleukin - beta gene, human monocytic cells Options: cell_type, DNA_domain_or_region, protein_molecule, other_name

[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]

Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.

[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]

[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]

protein kinase C inhibitors, fibronectin, interleukin - beta gene, human monocytic cells

69896_task2

Sentence: Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "B-other_name", "I-other_name", "I-other_name", "I-other_name", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O", "O", "O", "O", "O", "O", "O", "B-cell_type", "I-cell_type", "I-cell_type", "O" ]

Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-beta gene transcription, protein synthesis and secretion in human monocytic cells.

[ "Differential", "effects", "of", "protein", "kinase", "C", "inhibitors", "on", "fibronectin", "-", "induced", "interleukin", "-", "beta", "gene", "transcription", ",", "protein", "synthesis", "and", "secretion", "in", "human", "monocytic", "cells", "." ]

[ "other_name", "protein_molecule", "cell_type", "cell_line", "DNA_domain_or_region", "protein_family_or_group", "other_organic_compound" ]

Brain activity correlates is a Participant_Condition, synchronisation is a Intervention_Physical, continuation is a Intervention_Physical, paced finger tapping is a Intervention_Physical, Activity in parts of the human motor system is a Outcome_Physical, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) is a Intervention_Physical, continued tapping in absence of the auditory pacer is a Intervention_Physical, activation of bilateral SMA and basal ganglia is a Outcome_Physical

17402_task0

Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Physical, Outcome_Physical, Participant_Condition

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Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .

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[ "Intervention_Physical", "Outcome_Physical", "Participant_Condition" ]

Brain activity correlates is a Participant_Condition, synchronisation is a Intervention_Physical, continuation is a Intervention_Physical, paced finger tapping is a Intervention_Physical, Activity in parts of the human motor system is a Outcome_Physical, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) is a Intervention_Physical, continued tapping in absence of the auditory pacer is a Intervention_Physical, activation of bilateral SMA and basal ganglia is a Outcome_Physical

17402_task1

Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please typing these entity words according to sentence: Brain activity correlates, synchronisation, continuation, paced finger tapping, Activity in parts of the human motor system, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ), continued tapping in absence of the auditory pacer, activation of bilateral SMA and basal ganglia Options: Intervention_Physical, Outcome_Physical, Participant_Condition

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Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .

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[ "Intervention_Physical", "Outcome_Physical", "Participant_Condition" ]

Brain activity correlates, synchronisation, continuation, paced finger tapping, Activity in parts of the human motor system, movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ), continued tapping in absence of the auditory pacer, activation of bilateral SMA and basal ganglia

17402_task2

Sentence: Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues . Instructions: please extract entity words from the input sentence

[ "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "I-Intervention_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "I-Outcome_Physical", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation , synchronisation , and continuation phases of paced finger tapping . Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved , number of movements , and number of trajectories . Here , we searched for activity correlating with temporal complexity , in terms of the number of different intervals produced in the sequence , using an overlearned tapping task . Our task was divided into three phases : movement selection and initiation ( initiate ) , synchronisation of finger tapping with an external auditory cue ( synchronise ) , and continued tapping in absence of the auditory pacer ( continue ) . Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping . Thus , activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping . Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex ( SMA and preSMA ) , rostral dorsal premotor cortex ( PMC ) , basal ganglia , and dorsolateral prefrontal cortex ( DLPFC ) , among other areas . During synchronise , correlated activity was observed in bilateral SMA , more caudal dorsal and ventral PMC , right DLPFC and right primary motor cortex . No correlated activity was observed during continue at P < 0.01 ( corrected , cluster level ) , though left angular gyrus was active at P < 0.05 . We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters , while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction . The absence of activity significantly correlated with temporal complexity during continue suggests that , once an overlearned timed movement sequence has been selected and initiated , there is no further adjustment of the timing control processes related to its continued production in absence of external cues .

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[ "Intervention_Physical", "Outcome_Physical", "Participant_Condition" ]

surgical treatment is a Intervention_Physical, cancer of the thyroid gland ] is a Participant_Condition

76651_task0

Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Physical, Participant_Condition

[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]

[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .

[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]

[ "Participant_Condition", "Intervention_Physical" ]

surgical treatment is a Intervention_Physical, cancer of the thyroid gland ] is a Participant_Condition

76651_task1

Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please typing these entity words according to sentence: surgical treatment, cancer of the thyroid gland ] Options: Intervention_Physical, Participant_Condition

[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]

[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .

[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]

[ "Participant_Condition", "Intervention_Physical" ]

surgical treatment, cancer of the thyroid gland ]

76651_task2

Sentence: [ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] . Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "O", "B-Intervention_Physical", "I-Intervention_Physical", "O", "B-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "I-Participant_Condition", "O" ]

[ Randomized cooperative studies of the surgical treatment of cancer of the thyroid gland ] .

[ "[", "Randomized", "cooperative", "studies", "of", "the", "surgical", "treatment", "of", "cancer", "of", "the", "thyroid", "gland", "]", "." ]

[ "Participant_Condition", "Intervention_Physical" ]

MurD is a protein, UMA is a compound

DS.d797_task0

Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: compound, protein

[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).

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[ "compound", "protein" ]

MurD is a protein, UMA is a compound

DS.d797_task1

Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please typing these entity words according to sentence: MurD, UMA Options: compound, protein

[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).

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[ "compound", "protein" ]

MurD, UMA

DS.d797_task2

Sentence: MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i). Instructions: please extract entity words from the input sentence

[ "B-protein", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-compound", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

MurD (UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase), a three-domain bacterial protein, catalyses a highly specific incorporation of D-glutamate to the cytoplasmic intermediate UDP-N-acetyl-muramoyl-L-alanine (UMA) utilizing ATP hydrolysis to ADP and P(i).

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[ "compound", "protein" ]

Behandlung is an umlsterm, Hauptstammstenosen is an umlsterm, Koronararterie is an umlsterm, Notfall - Eingriff is an umlsterm, Myokardinfarkt is an umlsterm, perkutane transluminale Angioplastie is an umlsterm, Mortalitaet is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Koronararterie is an umlsterm, Risiko is an umlsterm, Notfall - Eingriff is an umlsterm, Risiko is an umlsterm

ZfuerKardiologie.00890508.ger.abstr_task0

Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

[ "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .

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[ "umlsterm" ]

Behandlung is an umlsterm, Hauptstammstenosen is an umlsterm, Koronararterie is an umlsterm, Notfall - Eingriff is an umlsterm, Myokardinfarkt is an umlsterm, perkutane transluminale Angioplastie is an umlsterm, Mortalitaet is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Patienten is an umlsterm, Koronararterie is an umlsterm, Risiko is an umlsterm, Notfall - Eingriff is an umlsterm, Risiko is an umlsterm

ZfuerKardiologie.00890508.ger.abstr_task1

Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please typing these entity words according to sentence: Behandlung, Hauptstammstenosen, Koronararterie, Notfall - Eingriff, Myokardinfarkt, perkutane transluminale Angioplastie, Mortalitaet, Patienten, Patienten, Patienten, Koronararterie, Risiko, Notfall - Eingriff, Risiko Options: umlsterm

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Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .

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[ "umlsterm" ]

Behandlung, Hauptstammstenosen, Koronararterie, Notfall - Eingriff, Myokardinfarkt, perkutane transluminale Angioplastie, Mortalitaet, Patienten, Patienten, Patienten, Koronararterie, Risiko, Notfall - Eingriff, Risiko

ZfuerKardiologie.00890508.ger.abstr_task2

Sentence: Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden . Instructions: please extract entity words from the input sentence

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Die Behandlung hochgradiger symptomatischer Hauptstammstenosen der linken Koronararterie ist die operative Revaskularisation . Bei geschuetztem Hauptstamm durch vorangegangene Bypass-Operation oder als Notfall-Eingriff im akuten Myokardinfarkt mit kardiogenem Schock wird die perkutane transluminale Angioplastie als Behandlungsalternative durchgefuehrt . Die Durchsicht von 262 Interventionen ergab eine Mortalitaet der Intervention von 9,1% ( 4/44 ) bei Patienten ohne Hauptstamm-Protektion , 4,8% ( 1/21 ) bei Patienten mit Kollateralen und 0,5% ( 1/197 ) bei Patienten mit offenem Bypass-Gefaess zu einem der Gefaesse der linken Koronararterie . Die koronare Agioplastie des ungeschuetzten Hauptstamms hat ein nicht akzeptables Risiko und sollte daher auch als Notfall-Eingriff nicht durchgefuehrt werden . Das Risiko der Hauptstamm-PTCA kann durch die vorgeschlagene Einteilung der Hauptstamm-Protektion durchgefuehrt werden .

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[ "umlsterm" ]

between 7 to 70 years is a Value, age is a Person, fluent in English is a Observation, plans to is a Mood, receive care is a Procedure, Community Health Center is a Visit, during the next year is a Temporal, signs and symptoms is a Scope, SSTI is a Condition

NCT02566928_inc_task0

Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Temporal, Condition, Value, Person, Observation, Visit, Procedure, Scope, Mood

[ "B-Value", "I-Value", "I-Value", "I-Value", "I-Value", "O", "B-Person", "O", "B-Observation", "I-Observation", "I-Observation", "O", "O", "O", "B-Mood", "I-Mood", "B-Procedure", "I-Procedure", "O", "O", "B-Visit", "I-Visit", "I-Visit", "B-Temporal", "I-Temporal", "I-Temporal", "I-Temporal", "O", "O", "O", "B-Scope", "I-Scope", "I-Scope", "O", "O", "B-Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent

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[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]

between 7 to 70 years is a Value, age is a Person, fluent in English is a Observation, plans to is a Mood, receive care is a Procedure, Community Health Center is a Visit, during the next year is a Temporal, signs and symptoms is a Scope, SSTI is a Condition

NCT02566928_inc_task1

Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please typing these entity words according to sentence: between 7 to 70 years, age, fluent in English, plans to, receive care, Community Health Center, during the next year, signs and symptoms, SSTI Options: Temporal, Condition, Value, Person, Observation, Visit, Procedure, Scope, Mood

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between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent

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[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]

between 7 to 70 years, age, fluent in English, plans to, receive care, Community Health Center, during the next year, signs and symptoms, SSTI

NCT02566928_inc_task2

Sentence: between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent Instructions: please extract entity words from the input sentence

[ "B-Value", "I-Value", "I-Value", "I-Value", "I-Value", "O", "B-Person", "O", "B-Observation", "I-Observation", "I-Observation", "O", "O", "O", "B-Mood", "I-Mood", "B-Procedure", "I-Procedure", "O", "O", "B-Visit", "I-Visit", "I-Visit", "B-Temporal", "I-Temporal", "I-Temporal", "I-Temporal", "O", "O", "O", "B-Scope", "I-Scope", "I-Scope", "O", "O", "B-Condition", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

between 7 to 70 years of age fluent in English or Spanish plans to receive care in the Community Health Center during the next year presents with signs and symptoms of a SSTI willing/able to provide informed consent

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[ "Visit", "Value", "Temporal", "Scope", "Observation", "Procedure", "Mood", "Condition", "Person" ]

tissues is a Tissue, tissue is a Tissue, tree ring is a Tissue, leaf is a Organ, leaf is a Organ, stem tissue is a Tissue, crowns is a Organism_subdivision, woody tissue is a Tissue, branch wood is a Multi-tissue_structure, tree ring is a Tissue

PMID-17617824_task0

Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Multi-tissue_structure, Organism_subdivision, Tissue, Organ

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Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.

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[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]

tissues is a Tissue, tissue is a Tissue, tree ring is a Tissue, leaf is a Organ, leaf is a Organ, stem tissue is a Tissue, crowns is a Organism_subdivision, woody tissue is a Tissue, branch wood is a Multi-tissue_structure, tree ring is a Tissue

PMID-17617824_task1

Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please typing these entity words according to sentence: tissues, tissue, tree ring, leaf, leaf, stem tissue, crowns, woody tissue, branch wood, tree ring Options: Multi-tissue_structure, Organism_subdivision, Tissue, Organ

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Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.

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[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]

tissues, tissue, tree ring, leaf, leaf, stem tissue, crowns, woody tissue, branch wood, tree ring

PMID-17617824_task2

Sentence: Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions. Instructions: please extract entity words from the input sentence

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Rapid mixing between old and new C pools in the canopy of mature forest trees. Stable C isotope signals in plant tissues became a key tool in explaining growth responses to the environment. The technique is based on the fundamental assumption that the isotopic composition of a given unit of tissue (e.g. a tree ring) reflects the specific C uptake conditions in the leaf at a given time. Beyond the methodological implications of any deviation from this assumption, it is of physiological interest whether new C is transferred directly from sources (a photosynthesizing leaf) to structural sinks (e.g. adjacent stem tissue), or inherently passes through existing (mobile) C pools, which may be of variable (older) age. Here, we explore the fate of (13)C-labelled photosynthates in the crowns of a 30-35 m tall, mixed forest using a canopy crane. In all nine study species labelled C reached woody tissue within 2-9 h after labelling. Four months later, very small signals were left in branch wood of Tilia suggesting that low mixing of new, labelled C with old C had taken place. In contrast, signals in Fagus and Quercus had increased, indicating more intense mixing. This species-specific mixing of new with old C pools is likely to mask year- or season-specific linkages between tree ring formation and climate and has considerable implications for climate reconstruction using stable isotopes as proxies for past climatic conditions.

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[ "Tissue", "Multi-tissue_structure", "Organism_subdivision", "Organ" ]

Kindern is an umlsterm, Diabetes mellitus is an umlsterm, Hypoglykaemie is an umlsterm, jugendlichen is an umlsterm, Eltern is an umlsterm, Ethikkommission is an umlsterm, Insulin - induzierte is an umlsterm

MonatsschriftKinderheilkunde.71450120.ger.abstr_task0

Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]

Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .

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[ "umlsterm" ]

Kindern is an umlsterm, Diabetes mellitus is an umlsterm, Hypoglykaemie is an umlsterm, jugendlichen is an umlsterm, Eltern is an umlsterm, Ethikkommission is an umlsterm, Insulin - induzierte is an umlsterm

MonatsschriftKinderheilkunde.71450120.ger.abstr_task1

Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please typing these entity words according to sentence: Kindern, Diabetes mellitus, Hypoglykaemie, jugendlichen, Eltern, Ethikkommission, Insulin - induzierte Options: umlsterm

[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]

Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .

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[ "umlsterm" ]

Kindern, Diabetes mellitus, Hypoglykaemie, jugendlichen, Eltern, Ethikkommission, Insulin - induzierte

MonatsschriftKinderheilkunde.71450120.ger.abstr_task2

Sentence: Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch . Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O" ]

Fragestellung : Um die bei Kindern mit juvenilem Diabetes mellitus wenig untersuchten Erstsymptome und die adrenerge Antwort in der Hypoglykaemie zu charakterisieren , fuehrten wir bei 23 jugendlichen Diabetikern in Begleitung ihrer Eltern eine von der Ethikkommission genehmigte milde Insulin-induzierte Unterzuckerung durch .

[ "Fragestellung", ":", "Um", "die", "bei", "Kindern", "mit", "juvenilem", "Diabetes", "mellitus", "wenig", "untersuchten", "Erstsymptome", "und", "die", "adrenerge", "Antwort", "in", "der", "Hypoglykaemie", "zu", "charakterisieren", ",", "fuehrten", "wir", "bei", "23", "jugendlichen", "Diabetikern", "in", "Begleitung", "ihrer", "Eltern", "eine", "von", "der", "Ethikkommission", "genehmigte", "milde", "Insulin", "-", "induzierte", "Unterzuckerung", "durch", "." ]

[ "umlsterm" ]

putative benefits is a Outcome_Other, montelukast is a Intervention_Pharmacological, moderate persistent asthmatics is a Participant_Condition, patients with moderate to severe asthma is a Participant_Condition, ICS is a Intervention_Pharmacological, salmeterol is a Intervention_Pharmacological, Twenty is a Participant_Sample-size, moderate to severe persistent asthmatics is a Participant_Condition, montelukast 10 mg daily is a Intervention_Pharmacological, placebo is a Intervention_Control, sequence effects is a Outcome_Other, Methacholine PD20 values is a Outcome_Physical, Lung function deteriorated is a Outcome_Physical, FEF25 - 75 is a Outcome_Physical, FEV1 is a Outcome_Physical, diurnal peak expiratory flow is a Outcome_Physical, symptoms is a Outcome_Physical, salbutamol use is a Outcome_Other

13217_task0

Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Pharmacological, Intervention_Control, Participant_Condition, Outcome_Physical, Participant_Sample-size, Outcome_Other

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A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .

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[ "Participant_Condition", "Outcome_Physical", "Intervention_Pharmacological", "Outcome_Other", "Intervention_Control", "Participant_Sample-size" ]

putative benefits is a Outcome_Other, montelukast is a Intervention_Pharmacological, moderate persistent asthmatics is a Participant_Condition, patients with moderate to severe asthma is a Participant_Condition, ICS is a Intervention_Pharmacological, salmeterol is a Intervention_Pharmacological, Twenty is a Participant_Sample-size, moderate to severe persistent asthmatics is a Participant_Condition, montelukast 10 mg daily is a Intervention_Pharmacological, placebo is a Intervention_Control, sequence effects is a Outcome_Other, Methacholine PD20 values is a Outcome_Physical, Lung function deteriorated is a Outcome_Physical, FEF25 - 75 is a Outcome_Physical, FEV1 is a Outcome_Physical, diurnal peak expiratory flow is a Outcome_Physical, symptoms is a Outcome_Physical, salbutamol use is a Outcome_Other

13217_task1

Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please typing these entity words according to sentence: putative benefits, montelukast, moderate persistent asthmatics, patients with moderate to severe asthma, ICS, salmeterol, Twenty, moderate to severe persistent asthmatics, montelukast 10 mg daily, placebo, sequence effects, Methacholine PD20 values, Lung function deteriorated, FEF25 - 75, FEV1, diurnal peak expiratory flow, symptoms, salbutamol use Options: Intervention_Pharmacological, Intervention_Control, Participant_Condition, Outcome_Physical, Participant_Sample-size, Outcome_Other

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A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .

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[ "Participant_Condition", "Outcome_Physical", "Intervention_Pharmacological", "Outcome_Other", "Intervention_Control", "Participant_Sample-size" ]

putative benefits, montelukast, moderate persistent asthmatics, patients with moderate to severe asthma, ICS, salmeterol, Twenty, moderate to severe persistent asthmatics, montelukast 10 mg daily, placebo, sequence effects, Methacholine PD20 values, Lung function deteriorated, FEF25 - 75, FEV1, diurnal peak expiratory flow, symptoms, salbutamol use

13217_task2

Sentence: A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes . Instructions: please extract entity words from the input sentence

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A proof of concept study to evaluate putative benefits of montelukast in moderate persistent asthmatics . AIMS Whether chronic dosing with montelukast confers benefit in patients with moderate to severe asthma remains to be fully established . A proof of concept study was performed evaluating putative benefits with montelukast in moderate persistent asthmatics who were taken off inhaled corticosteroids ( ICS ) and switched to salmeterol . The latter was done to dissociate the effects of montelukast from ICS . METHODS Twenty moderate to severe persistent asthmatics completed a randomized double-blind crossover study . Subjects received montelukast 10 mg daily or placebo for 2 weeks each . This was preceded by a 2-week run-in when ICS were discontinued and salmeterol started , and used on a regular basis throughout the study . Measurements were made after run-in and after both randomized treatments . RESULTS There were no significant sequence effects for responses as to whether placebo or montelukast were given first or second . Methacholine PD20 values after run-in , first and second placebo were 63 micro g , 60 micro g and 64 micro g , respectively ( corresponding to 2 , 4 and 6 weeks of ICS washout , respectively ) . Lung function deteriorated pre vs post run-in , which was significant ( P < 0.05 ) for FEF25-75 % predicted . Montelukast conferred significant ( P < 0.05 ) improvements as change from post run-in compared with placebo in methacholine PD20 , FEV1 % predicted , FEF25-75 % predicted , diurnal peak expiratory flow , symptoms and salbutamol use . For the primary outcome of methacholine PD20 , this amounted to a 1.6-fold difference ( 95 % CI 1.1 , 2.5 ) . CONCLUSIONS In moderate persistent asthmatics switched from taking ICS to salmeterol alone , adding montelukast conferred significant benefits on all parameters of asthma control . Further studies are indicated to evaluate whether montelukast exhibits additive effects to ICS/long-acting beta2-adrenoceptor agonist combination inhalers upon clinically important outcomes .

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[ "Participant_Condition", "Outcome_Physical", "Intervention_Pharmacological", "Outcome_Other", "Intervention_Control", "Participant_Sample-size" ]

psychoanalysis is an umlsterm, elements is an umlsterm, publications is an umlsterm, films is an umlsterm, psychoanalysis is an umlsterm, work is an umlsterm, patient is an umlsterm, confusion is an umlsterm, patient is an umlsterm, abuse is an umlsterm, psychoanalysis is an umlsterm, thesis is an umlsterm, psychoanalysis is an umlsterm, body - therapy is an umlsterm

ForumDerPsychoanalyse.80140342.eng.abstr_task0

Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .

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[ "umlsterm" ]

psychoanalysis is an umlsterm, elements is an umlsterm, publications is an umlsterm, films is an umlsterm, psychoanalysis is an umlsterm, work is an umlsterm, patient is an umlsterm, confusion is an umlsterm, patient is an umlsterm, abuse is an umlsterm, psychoanalysis is an umlsterm, thesis is an umlsterm, psychoanalysis is an umlsterm, body - therapy is an umlsterm

ForumDerPsychoanalyse.80140342.eng.abstr_task1

Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please typing these entity words according to sentence: psychoanalysis, elements, publications, films, psychoanalysis, work, patient, confusion, patient, abuse, psychoanalysis, thesis, psychoanalysis, body - therapy Options: umlsterm

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The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .

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ForumDerPsychoanalyse.80140342.eng.abstr_task2

Sentence: The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts . Instructions: please extract entity words from the input sentence

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The author discusses critically the " extension " of psychoanalysis through " body-therapeutical elements " by Tilmann Moser . She demonstrates on the basis of the publications of Moser on this topic , especially of his didactical films about psychoanalysis and body work , how some acts between therapist and patient which are to understand sexually and are also experienced as such , are systematically reinterpreted by Moser as " preverbal " and " preoedipal " . This reinterpretation leads to the manipulative confusion of the patient and corresponds to the structure of abuse sceneries . Theoretical reflections about healing phantasies and about the concept of abstinence in psychoanalysis follow and on their basis the thesis is substantiated , that psychoanalysis and body-therapy are incompatible concepts .

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[ "umlsterm" ]

Colour is an umlsterm, measurements is an umlsterm, cocaine is an umlsterm, measurements is an umlsterm, halogen is an umlsterm, light is an umlsterm, standard is an umlsterm, Colorimetric is an umlsterm, classification is an umlsterm, chemical composition is an umlsterm, method is an umlsterm, orientation is an umlsterm, origin is an umlsterm

Rechtsmedizin.90090218.eng.abstr_task0

Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]

Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .

[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "L*a*b*-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "L*a*b*-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]

[ "umlsterm" ]

Colour is an umlsterm, measurements is an umlsterm, cocaine is an umlsterm, measurements is an umlsterm, halogen is an umlsterm, light is an umlsterm, standard is an umlsterm, Colorimetric is an umlsterm, classification is an umlsterm, chemical composition is an umlsterm, method is an umlsterm, orientation is an umlsterm, origin is an umlsterm

Rechtsmedizin.90090218.eng.abstr_task1

Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please typing these entity words according to sentence: Colour, measurements, cocaine, measurements, halogen, light, standard, Colorimetric, classification, chemical composition, method, orientation, origin Options: umlsterm

[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]

Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .

[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "L*a*b*-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "L*a*b*-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]

[ "umlsterm" ]

Colour, measurements, cocaine, measurements, halogen, light, standard, Colorimetric, classification, chemical composition, method, orientation, origin

Rechtsmedizin.90090218.eng.abstr_task2

Sentence: Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin . Instructions: please extract entity words from the input sentence

[ "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O" ]

Colour measurements were performed on powdery substances of whitish to slightly yellow colouring ( cocaine samples of different composition ) in order to give an unequivocal optical description of the samples and relate them to control samples . The measurements were carried out with a spectrophotometer ( Carl-Zeiss-Jena GmbH , MCS 400 ) using a halogen bulb as light source ( standard illuminant D65). Colorimetric classification was made on the basis of the CIE-L*a*b*-values. The examination showed that specimens of similar or different chemical composition which could not be distinguished macroscopically revealed characteristic differences in the CIE-L*a*b*-measures. The method gives a first clue for orientation within a few minutes when comparing substances in specimens of different origin .

[ "Colour", "measurements", "were", "performed", "on", "powdery", "substances", "of", "whitish", "to", "slightly", "yellow", "colouring", "(", "cocaine", "samples", "of", "different", "composition", ")", "in", "order", "to", "give", "an", "unequivocal", "optical", "description", "of", "the", "samples", "and", "relate", "them", "to", "control", "samples", ".", "The", "measurements", "were", "carried", "out", "with", "a", "spectrophotometer", "(", "Carl", "-", "Zeiss", "-", "Jena", "GmbH", ",", "MCS", "400", ")", "using", "a", "halogen", "bulb", "as", "light", "source", "(", "standard", "illuminant", "D65", ")", ".", "Colorimetric", "classification", "was", "made", "on", "the", "basis", "of", "the", "CIE", "-", "L*a*b*-values", ".", "The", "examination", "showed", "that", "specimens", "of", "similar", "or", "different", "chemical", "composition", "which", "could", "not", "be", "distinguished", "macroscopically", "revealed", "characteristic", "differences", "in", "the", "CIE", "-", "L*a*b*-measures", ".", "The", "method", "gives", "a", "first", "clue", "for", "orientation", "within", "a", "few", "minutes", "when", "comparing", "substances", "in", "specimens", "of", "different", "origin", "." ]

[ "umlsterm" ]

Epstein - Barr virus BamHI W promoter is a DNA_domain_or_region

69080_task0

Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: DNA_domain_or_region

[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.

[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]

[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]

Epstein - Barr virus BamHI W promoter is a DNA_domain_or_region

69080_task1

Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please typing these entity words according to sentence: Epstein - Barr virus BamHI W promoter Options: DNA_domain_or_region

[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.

[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]

[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]

Epstein - Barr virus BamHI W promoter

69080_task2

Sentence: Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Characterisation of regulatory sequences at the Epstein-Barr virus BamHI W promoter.

[ "Characterisation", "of", "regulatory", "sequences", "at", "the", "Epstein", "-", "Barr", "virus", "BamHI", "W", "promoter", "." ]

[ "DNA_domain_or_region", "other_name", "DNA_family_or_group", "cell_component", "virus", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "protein_family_or_group", "cell_line", "cell_type", "" ]

actin is a Individual_protein, fimbrin is a Individual_protein

803_task0

Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Individual_protein

[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]

The structure of an actin-crosslinking domain from human fimbrin.

[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]

[ "Individual_protein" ]

actin is a Individual_protein, fimbrin is a Individual_protein

803_task1

Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please typing these entity words according to sentence: actin, fimbrin Options: Individual_protein

[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]

The structure of an actin-crosslinking domain from human fimbrin.

[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]

[ "Individual_protein" ]

actin, fimbrin

803_task2

Sentence: The structure of an actin-crosslinking domain from human fimbrin. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "B-Individual_protein", "O", "O", "O", "O", "O", "B-Individual_protein", "O" ]

The structure of an actin-crosslinking domain from human fimbrin.

[ "The", "structure", "of", "an", "actin", "-", "crosslinking", "domain", "from", "human", "fimbrin", "." ]

[ "Individual_protein" ]

fractures is an umlsterm, spine is an umlsterm, separation is an umlsterm, injury is an umlsterm, spinal cord is an umlsterm, fracture is an umlsterm, arc is an umlsterm, fracture is an umlsterm, set is an umlsterm, X - rays is an umlsterm, trauma is an umlsterm, treatment is an umlsterm, open is an umlsterm

Trauma+Berufskrankheit.80010071.eng.abstr_task0

Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

[ "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .

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[ "umlsterm" ]

fractures is an umlsterm, spine is an umlsterm, separation is an umlsterm, injury is an umlsterm, spinal cord is an umlsterm, fracture is an umlsterm, arc is an umlsterm, fracture is an umlsterm, set is an umlsterm, X - rays is an umlsterm, trauma is an umlsterm, treatment is an umlsterm, open is an umlsterm

Trauma+Berufskrankheit.80010071.eng.abstr_task1

Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please typing these entity words according to sentence: fractures, spine, separation, injury, spinal cord, fracture, arc, fracture, set, X - rays, trauma, treatment, open Options: umlsterm

[ "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .

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[ "umlsterm" ]

fractures, spine, separation, injury, spinal cord, fracture, arc, fracture, set, X - rays, trauma, treatment, open

Trauma+Berufskrankheit.80010071.eng.abstr_task2

Sentence: Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column . Instructions: please extract entity words from the input sentence

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Complete dislocated fractures of the thoracic spine may have no neurological deficits if separation is present in the middle of the dorsal column . In this case there is no injury to the spinal cord , because the " saving fracture " of the vertebral arc prevents it . One case of a severe dislocated fracture at T11-12 is reported . In practice , a complete set of X-rays should be done after high-speed trauma , even if no neurological deficit is present . The treatment is operative by open reduction and fusion from the ventral or dorsal column .

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Matías is a NOMBRE_SUJETO_ASISTENCIA, San Martin Fernandez is a NOMBRE_SUJETO_ASISTENCIA, 2756849 is a ID_SUJETO_ASISTENCIA, 47 98563794 10 is a ID_ASEGURAMIENTO, Pontevedra is a TERRITORIO, 36071 is a TERRITORIO, 07/05/1990 is a FECHAS, España is a PAIS, 09/04/2012 is a FECHAS, 7435703 is a ID_CONTACTO_ASISTENCIAL, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, 36 36 15748 is a ID_TITULACION_PERSONAL_SANITARIO, varón is a SEXO_SUJETO_ASISTENCIA, 21 años is a EDAD_SUJETO_ASISTENCIA, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, Hospital de Montecelo is a HOSPITAL, 36071 is a TERRITORIO, Pontevedra is a TERRITORIO, enrique.alemparte.pardavila@sergas.es is a CORREO_ELECTRONICO

158_task0

Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: TERRITORIO, SEXO_SUJETO_ASISTENCIA, ID_SUJETO_ASISTENCIA, FECHAS, HOSPITAL, CORREO_ELECTRONICO, PAIS, EDAD_SUJETO_ASISTENCIA, ID_CONTACTO_ASISTENCIAL, ID_ASEGURAMIENTO, ID_TITULACION_PERSONAL_SANITARIO, NOMBRE_SUJETO_ASISTENCIA, NOMBRE_PERSONAL_SANITARIO

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Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es

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[ "CORREO_ELECTRONICO", "NOMBRE_PERSONAL_SANITARIO", "CALLE", "HOSPITAL", "NOMBRE_SUJETO_ASISTENCIA", "ID_ASEGURAMIENTO", "ID_TITULACION_PERSONAL_SANITARIO", "TERRITORIO", "FECHAS", "EDAD_SUJETO_ASISTENCIA", "ID_CONTACTO_ASISTENCIAL", "ID_SUJETO_ASISTENCIA", "PAIS", "SEXO_SUJETO_ASISTENCIA" ]

Matías is a NOMBRE_SUJETO_ASISTENCIA, San Martin Fernandez is a NOMBRE_SUJETO_ASISTENCIA, 2756849 is a ID_SUJETO_ASISTENCIA, 47 98563794 10 is a ID_ASEGURAMIENTO, Pontevedra is a TERRITORIO, 36071 is a TERRITORIO, 07/05/1990 is a FECHAS, España is a PAIS, 09/04/2012 is a FECHAS, 7435703 is a ID_CONTACTO_ASISTENCIAL, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, 36 36 15748 is a ID_TITULACION_PERSONAL_SANITARIO, varón is a SEXO_SUJETO_ASISTENCIA, 21 años is a EDAD_SUJETO_ASISTENCIA, Enrique Alemparte Pardavila is a NOMBRE_PERSONAL_SANITARIO, Hospital de Montecelo is a HOSPITAL, 36071 is a TERRITORIO, Pontevedra is a TERRITORIO, enrique.alemparte.pardavila@sergas.es is a CORREO_ELECTRONICO

158_task1

Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es Instructions: please typing these entity words according to sentence: Matías, San Martin Fernandez, 2756849, 47 98563794 10, Pontevedra, 36071, 07/05/1990, España, 09/04/2012, 7435703, Enrique Alemparte Pardavila, 36 36 15748, varón, 21 años, Enrique Alemparte Pardavila, Hospital de Montecelo, 36071, Pontevedra, enrique.alemparte.pardavila@sergas.es Options: TERRITORIO, SEXO_SUJETO_ASISTENCIA, ID_SUJETO_ASISTENCIA, FECHAS, HOSPITAL, CORREO_ELECTRONICO, PAIS, EDAD_SUJETO_ASISTENCIA, ID_CONTACTO_ASISTENCIAL, ID_ASEGURAMIENTO, ID_TITULACION_PERSONAL_SANITARIO, NOMBRE_SUJETO_ASISTENCIA, NOMBRE_PERSONAL_SANITARIO

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Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es

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[ "CORREO_ELECTRONICO", "NOMBRE_PERSONAL_SANITARIO", "CALLE", "HOSPITAL", "NOMBRE_SUJETO_ASISTENCIA", "ID_ASEGURAMIENTO", "ID_TITULACION_PERSONAL_SANITARIO", "TERRITORIO", "FECHAS", "EDAD_SUJETO_ASISTENCIA", "ID_CONTACTO_ASISTENCIAL", "ID_SUJETO_ASISTENCIA", "PAIS", "SEXO_SUJETO_ASISTENCIA" ]

Matías, San Martin Fernandez, 2756849, 47 98563794 10, Pontevedra, 36071, 07/05/1990, España, 09/04/2012, 7435703, Enrique Alemparte Pardavila, 36 36 15748, varón, 21 años, Enrique Alemparte Pardavila, Hospital de Montecelo, 36071, Pontevedra, enrique.alemparte.pardavila@sergas.es

158_task2

Sentence: Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es Instructions: please extract entity words from the input sentence

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Datos del paciente. Nombre: Matías. Apellidos: San Martin Fernandez. NHC: 2756849. NASS: 47 98563794 10. Domicilio: C/ Molineros, 28, 6, A. Localidad/ Provincia: Pontevedra . CP: 36071. Datos asistenciales. Fecha de nacimiento: 07/05/1990. País de nacimiento: España. Edad:21 años Sexo: H. Fecha de Ingreso: 09/04/2012. Servicio: Urgencias. Episodio: 7435703. Médico: Enrique Alemparte Pardavila NºCol: 36 36 15748. Informe clínico del paciente: Paciente varón de 21 años, sin alergias conocidas ni otros antecedentes, que acude a urgencias por un cuadro clínico de 6 meses de astenia, aumento de la fatiga con el ejercicio moderado y acompañado de síndrome general con disminución de peso en dichos meses de unos 10 kilos. Debido a episodios de dolor abdominal en este período acudió en dos ocasiones un Servicio de Urgencias y fue sometido a la realización de una gastroscopia informada como de mínima hernia de hiato con esofagitis grado I y reflujo biliar duodeno-gástrico. En los últimos 5 días se exacerba la clínica, presentando además vómitos, dolor abdominal difuso más intenso y deposiciones líquidas sin aumento del número de las mismas. A la exploración física presenta una tensión arterial de 120/60 mmHg, frecuencia cardíaca de 110 pm, afebril, consciente y orientado, sin focalidad neurológica, eupneico, la auscultación cardíaca es rítmica, taquicárdica, sin soplos, el abdomen es blando y depresible, doloroso de forma difusa, sin defensa a la palpación, no se palpan masas ni megalias. Destaca la hiperpigmentación cutánea generalizada, acentuada en pezones, área genital y con manchas melánicas en paladar y bordes gingivales. La analítica a su ingreso muestra una glucemia de 59 mg/dL, creatinina 4,32 mg/dL, urea 214 mg/dL, Na 123 mg/dL, K 8,0 mg/dL, Ca 8,2 mg/dL, una gasometría arterial con un pH 7,24, pCO2 35,6 mmHg, pO2 107 mmHg (con O2 a 4 litros/minuto), bicarbonato 14,4 mmol/L, EB - 11,3 mmol/L y SatO2 del 97,2%. El hemograma presenta una hemoglobina de 13,4 g/dl, hematocrito 39,5%, VCM 83 fL, leucocitos 12.800 (45% neutrófilos, 32% linfocitos, 12% monocitos y 10,5% eosinofilos). Coagulación sin alteraciones. El electrocardiograma presenta una taquicardia sinusal a 110 lpm con configuración RSR' y prolongación de QT (487 ms). La radiografía de tórax es normal. Durante su estancia en urgencias se inician medidas para la corrección de la hiperpotasemia pero el paciente progresivamente se encuentra más sudoroso, taquicárdico e hipotenso (TA 85/46 mmHg) por lo que, con la sospecha de crisis adisoniana se decide su ingreso en la UCI y se inicia la reposición de volumen con suero salino ( 4.500 cc en las primeras 24 horas), aporte de glucosa, actocortina (100 mg i.v. en bolo seguidos de 400 mg en perfusión intravenosa continua en las siguientes 24 horas); precisando inicialmente perfusión de aminas vasopresoras (dopamina a 10 mcg/kg/min), pudiendo ser retiradas en 36 horas. Las muestras sanguíneas tomadas previas al inicio del tratamiento corticoideo para determinación de la función suprarrenal mostraban un cortisol basal 4,0 mg/dL y una ACTH en plasma 264 pg/ml. La determinación de anticuerpos anti-cápsulas suprarrenales en suero por imnufluorescencia indirecta fue positiva con un título de 1/80. La determinación de tirotropina, tiroxina libre, FSH y LH, asi como anticuerpos antitiroglobulina y antiperoxidasa microsomial resultaron dentro de rangos normales. TAC abdominal: presencia de glándulas suprarrenales morfológicamente normales. El paciente fue dado de alta de la Unidad de Cuidados Intensivos a los 3 días de su ingreso y del hospital a los 7 días con parámetros analíticos de función renal e iones dentro de la normalidad y con tratamiento con hidroaltresona 20 mg vo/8 h. Responsable clínico: Dr. Enrique Alemparte Pardavila. Unidad de Cuidados Críticos. Hospital de Montecelo. Mourente, s/n. 36071 Pontevedra. e-mail: enrique.alemparte.pardavila@sergas.es

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[ "CORREO_ELECTRONICO", "NOMBRE_PERSONAL_SANITARIO", "CALLE", "HOSPITAL", "NOMBRE_SUJETO_ASISTENCIA", "ID_ASEGURAMIENTO", "ID_TITULACION_PERSONAL_SANITARIO", "TERRITORIO", "FECHAS", "EDAD_SUJETO_ASISTENCIA", "ID_CONTACTO_ASISTENCIAL", "ID_SUJETO_ASISTENCIA", "PAIS", "SEXO_SUJETO_ASISTENCIA" ]

transient ulnar artery compression is a Intervention_Physical, Patients referred for coronary angiography is a Participant_Condition, very - low - dose heparin is a Intervention_Pharmacological, 465 patients is a Participant_Sample-size, incidence of initial RAO is a Outcome_Physical

49862_task0

Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Intervention_Pharmacological, Intervention_Physical, Participant_Condition, Outcome_Physical, Participant_Sample-size

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Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .

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[ "Participant_Condition", "Intervention_Physical", "Outcome_Physical", "Intervention_Pharmacological", "Participant_Sample-size" ]

transient ulnar artery compression is a Intervention_Physical, Patients referred for coronary angiography is a Participant_Condition, very - low - dose heparin is a Intervention_Pharmacological, 465 patients is a Participant_Sample-size, incidence of initial RAO is a Outcome_Physical

49862_task1

Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . Instructions: please typing these entity words according to sentence: transient ulnar artery compression, Patients referred for coronary angiography, very - low - dose heparin, 465 patients, incidence of initial RAO Options: Intervention_Pharmacological, Intervention_Physical, Participant_Condition, Outcome_Physical, Participant_Sample-size

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Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .

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[ "Participant_Condition", "Intervention_Physical", "Outcome_Physical", "Intervention_Pharmacological", "Participant_Sample-size" ]

transient ulnar artery compression, Patients referred for coronary angiography, very - low - dose heparin, 465 patients, incidence of initial RAO

49862_task2

Sentence: Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level . Instructions: please extract entity words from the input sentence

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Efficacy and safety of transient ulnar artery compression to recanalize acute radial artery occlusion after transradial catheterization . Radial artery occlusion ( RAO ) can result from transradial catheterization . We compared the incidence of RAO with 2 heparin dosage regimens after transradial coronary angiography , and we evaluated the efficacy and safety of transient homolateral ulnar artery compression to achieve acute radial artery recanalization . Patients referred for coronary angiography were randomized to very-low-dose heparin ( 2,000 IU ) or low-dose heparin ( 5,000 IU ) . On sheath removal , hemostasis was obtained using the TR band with a plethysmography-guided patent hemostasis technique . In the case of RAO as assessed by duplex ultrasonography 3 to 4 hours after hemostasis , immediate 1-hour ulnar artery compression was applied . Hematomas > 15 cm ( 2 ) were also assessed . We randomized 465 patients , 222 in the 2,000-IU group and 243 in the 5,000-IU group . The baseline and procedural characteristics were comparable in both groups . The incidence of initial RAO was 5.9 % in the 2,000-IU group and 2.9 % in the 5,000-IU group ( p = 0.17 ) , with a compression time of 2.10 ± 0.78 hours and 2.25 ± 0.82 hours , respectively ( p = 0.051 ) . After ulnar artery compression , the final incidence of RAO was 4.1 % in the 2,000-IU group and 0.8 % in the 5,000-IU group ( p = 0.03 ) . The incidence of local hematoma was 2.3 % and 3.7 % in the 2,000- and 5,000-IU groups , respectively ( p = 0.42 ) . In conclusion , acute RAO after transradial catheterization can be recanalized by early 1-hour homolateral ulnar artery compression . This simple nonpharmacologic method was effective and safe in patients with very-low- and low-dose heparin . Nevertheless , the incidence of final RAO remained significantly lower after a higher anticoagulation level .

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[ "Participant_Condition", "Intervention_Physical", "Outcome_Physical", "Intervention_Pharmacological", "Participant_Sample-size" ]

cryotherapy is an umlsterm, morphological is an umlsterm, eyes is an umlsterm, retinopathy of prematurity is an umlsterm, visual acuity is an umlsterm, eyes is an umlsterm, cryocoagulation is an umlsterm, hospital is an umlsterm, gestational age is an umlsterm

DerOpthalmologe.90960786.eng.abstr_task0

Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .

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[ "umlsterm" ]

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DerOpthalmologe.90960786.eng.abstr_task1

Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please typing these entity words according to sentence: cryotherapy, morphological, eyes, retinopathy of prematurity, visual acuity, eyes, cryocoagulation, hospital, gestational age Options: umlsterm

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Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .

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[ "umlsterm" ]

cryotherapy, morphological, eyes, retinopathy of prematurity, visual acuity, eyes, cryocoagulation, hospital, gestational age

DerOpthalmologe.90960786.eng.abstr_task2

Sentence: Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age . Instructions: please extract entity words from the input sentence

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Background : The results of the Cryo-ROP group showed that cryotherapy significantly reduces the rate of adverse morphological and functional outcome of eyes with threshold retinopathy of prematurity . Structural status and visual acuity of 48 eyes which consecutively underwent cryocoagulation in our hospital between 1990 and 1994 were examined at 2 years corrected gestational age .

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[ "umlsterm" ]

patients is an umlsterm, major depression is an umlsterm, disorder is an umlsterm, sleep deprivation is an umlsterm, TSD is an umlsterm, TSD is an umlsterm, naps is an umlsterm, night 's is an umlsterm, methods is an umlsterm, sleep is an umlsterm, mood is an umlsterm, male is an umlsterm, patients is an umlsterm, major depression is an umlsterm, treatment is an umlsterm, patients is an umlsterm, mood is an umlsterm, treatment is an umlsterm, patients is an umlsterm

DerNervenarzt.80690066.eng.abstr_task0

Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .

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[ "umlsterm" ]

patients is an umlsterm, major depression is an umlsterm, disorder is an umlsterm, sleep deprivation is an umlsterm, TSD is an umlsterm, TSD is an umlsterm, naps is an umlsterm, night 's is an umlsterm, methods is an umlsterm, sleep is an umlsterm, mood is an umlsterm, male is an umlsterm, patients is an umlsterm, major depression is an umlsterm, treatment is an umlsterm, patients is an umlsterm, mood is an umlsterm, treatment is an umlsterm, patients is an umlsterm

DerNervenarzt.80690066.eng.abstr_task1

Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please typing these entity words according to sentence: patients, major depression, disorder, sleep deprivation, TSD, TSD, naps, night 's, methods, sleep, mood, male, patients, major depression, treatment, patients, mood, treatment, patients Options: umlsterm

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Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .

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[ "umlsterm" ]

patients, major depression, disorder, sleep deprivation, TSD, TSD, naps, night 's, methods, sleep, mood, male, patients, major depression, treatment, patients, mood, treatment, patients

DerNervenarzt.80690066.eng.abstr_task2

Sentence: Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups . Instructions: please extract entity words from the input sentence

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Approximately 60% of patients with major depression disorder show a beneficial response to total sleep deprivation ( TSD ) , but the positive effect of TSD is short , and naps or the following night's sleep destroy it . Various methods have been tried to stabilize the positive sleep-deprivation effect . A consecutive 1-week advance in the sleep phase stabilized mood in more than 50% of the sleep-deprivation responders . We examined 40 male patients with major depression who in addition to medical treatment took part in a phase advance study to prove possible synergistic effects . About 60% of the patients showed positive mood stabilization after 1-week of treatment when the patients were sleep-deprivation responders . These results support data from other groups .

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[ "umlsterm" ]

249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes is a participant

1296_task0

Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: participant

[ "O", "B-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "O" ]

Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .

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[ "participant", "intervention" ]

249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes is a participant

1296_task1

Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please typing these entity words according to sentence: 249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes Options: participant

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Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .

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[ "participant", "intervention" ]

249 adults from Washington State aged 55 to 75 with a doctor - confirmed diagnosis of osteoarthritis to participate in aquatic classes

1296_task2

Sentence: Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes . Instructions: please extract entity words from the input sentence

[ "O", "B-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "I-participant", "O" ]

Recruited 249 adults from Washington State aged 55 to 75 with a doctor-confirmed diagnosis of osteoarthritis to participate in aquatic classes .

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[ "participant", "intervention" ]

disease is an umlsterm, therapy is an umlsterm, head is an umlsterm, neck tumors is an umlsterm, radiotherapy is an umlsterm, patients is an umlsterm, tumors is an umlsterm, signs is an umlsterm, tumour is an umlsterm, assessment is an umlsterm, larynx is an umlsterm, laryngoscopy is an umlsterm, radiation is an umlsterm, laryngoscopy is an umlsterm, neck is an umlsterm, technique is an umlsterm, vocal cords is an umlsterm, -phonation is an umlsterm

DerRadiologe.80380122.eng.abstr_task0

Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .

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[ "umlsterm" ]

disease is an umlsterm, therapy is an umlsterm, head is an umlsterm, neck tumors is an umlsterm, radiotherapy is an umlsterm, patients is an umlsterm, tumors is an umlsterm, signs is an umlsterm, tumour is an umlsterm, assessment is an umlsterm, larynx is an umlsterm, laryngoscopy is an umlsterm, radiation is an umlsterm, laryngoscopy is an umlsterm, neck is an umlsterm, technique is an umlsterm, vocal cords is an umlsterm, -phonation is an umlsterm

DerRadiologe.80380122.eng.abstr_task1

Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please typing these entity words according to sentence: disease, therapy, head, neck tumors, radiotherapy, patients, tumors, signs, tumour, assessment, larynx, laryngoscopy, radiation, laryngoscopy, neck, technique, vocal cords, -phonation Options: umlsterm

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O" ]

The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .

[ "The", "importance", "of", "spiral", "-", "CT", "is", "clinically", "accepted", "for", "diagnosing", "spreading", "disease", "and", "for", "making", "a", "decision", "about", "the", "therapy", "strategy", "for", "head", "and", "neck", "tumors", ".", "Its", "importance", "for", "follow", "-", "up", "after", "radiotherapy", "was", "examined", "in", "26", "patients", "with", "irradiated", "laryngeal", "tumors", ".", "Using", "spiral", "-", "CT", "multiple", "signs", "of", "alterations", "(", "n", "=", "98", ")", "can", "be", "diagnosed", ",", "which", "are", "not", "only", "important", "for", "tumour", "relapse", ",", "but", "also", "for", "assessment", ".", "Spiral", "-", "CT", "offers", "the", "possibility", "of", "achieviny", "various", "additional", "information", "about", "the", "larynx", "that", "cannot", "be", "obtained", "with", "laryngoscopy", ".", "In", "follow", "-", "up", "examinations", "after", "radiation", ",", "laryngoscopy", "and", "spiral", "-", "CT", "are", "recommended", "as", "an", "integrated", "neck", "examination", "using", "the", "breath", "-", "holding", "technique", "(", "separately", "reconstructed", ")", "and", "also", "as", "functional", "spiral", "-", "CT", "of", "the", "vocal", "cords", "in", "\"", "I", "\"", "-phonation", "." ]

[ "umlsterm" ]

disease, therapy, head, neck tumors, radiotherapy, patients, tumors, signs, tumour, assessment, larynx, laryngoscopy, radiation, laryngoscopy, neck, technique, vocal cords, -phonation

DerRadiologe.80380122.eng.abstr_task2

Sentence: The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation . Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "B-umlsterm", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "B-umlsterm", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-umlsterm", "I-umlsterm", "O", "O", "O", "O", "B-umlsterm", "O" ]

The importance of spiral-CT is clinically accepted for diagnosing spreading disease and for making a decision about the therapy strategy for head and neck tumors . Its importance for follow-up after radiotherapy was examined in 26 patients with irradiated laryngeal tumors . Using spiral-CT multiple signs of alterations ( n = 98 ) can be diagnosed , which are not only important for tumour relapse , but also for assessment . Spiral-CT offers the possibility of achieviny various additional information about the larynx that cannot be obtained with laryngoscopy . In follow-up examinations after radiation , laryngoscopy and spiral-CT are recommended as an integrated neck examination using the breath-holding technique ( separately reconstructed ) and also as functional spiral-CT of the vocal cords in " I " -phonation .

[ "The", "importance", "of", "spiral", "-", "CT", "is", "clinically", "accepted", "for", "diagnosing", "spreading", "disease", "and", "for", "making", "a", "decision", "about", "the", "therapy", "strategy", "for", "head", "and", "neck", "tumors", ".", "Its", "importance", "for", "follow", "-", "up", "after", "radiotherapy", "was", "examined", "in", "26", "patients", "with", "irradiated", "laryngeal", "tumors", ".", "Using", "spiral", "-", "CT", "multiple", "signs", "of", "alterations", "(", "n", "=", "98", ")", "can", "be", "diagnosed", ",", "which", "are", "not", "only", "important", "for", "tumour", "relapse", ",", "but", "also", "for", "assessment", ".", "Spiral", "-", "CT", "offers", "the", "possibility", "of", "achieviny", "various", "additional", "information", "about", "the", "larynx", "that", "cannot", "be", "obtained", "with", "laryngoscopy", ".", "In", "follow", "-", "up", "examinations", "after", "radiation", ",", "laryngoscopy", "and", "spiral", "-", "CT", "are", "recommended", "as", "an", "integrated", "neck", "examination", "using", "the", "breath", "-", "holding", "technique", "(", "separately", "reconstructed", ")", "and", "also", "as", "functional", "spiral", "-", "CT", "of", "the", "vocal", "cords", "in", "\"", "I", "\"", "-phonation", "." ]

[ "umlsterm" ]

L - malic acid is a CHEMICAL

17203264_task0

Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: CHEMICAL

[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]

Fluorescent sensing layer for the determination of L-malic acid in wine.

[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]

[ "CHEMICAL", "GENE-N" ]

L - malic acid is a CHEMICAL

17203264_task1

Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please typing these entity words according to sentence: L - malic acid Options: CHEMICAL

[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]

Fluorescent sensing layer for the determination of L-malic acid in wine.

[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]

[ "CHEMICAL", "GENE-N" ]

L - malic acid

17203264_task2

Sentence: Fluorescent sensing layer for the determination of L-malic acid in wine. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "O", "O", "O", "O", "B-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "I-CHEMICAL", "O", "O", "O" ]

Fluorescent sensing layer for the determination of L-malic acid in wine.

[ "Fluorescent", "sensing", "layer", "for", "the", "determination", "of", "L", "-", "malic", "acid", "in", "wine", "." ]

[ "CHEMICAL", "GENE-N" ]

Emergency Department ( ED ) is a Visit, Acute Bacterial Skin and Skin Structure Infections is a Measurement, ABSSSI is a Measurement, gram - positive is a Qualifier, infection is a Condition

NCT02961764_inc_task0

Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: Condition, Measurement, Visit, Qualifier

[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]

Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.

[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]

[ "Measurement", "Visit", "Qualifier", "Condition" ]

Emergency Department ( ED ) is a Visit, Acute Bacterial Skin and Skin Structure Infections is a Measurement, ABSSSI is a Measurement, gram - positive is a Qualifier, infection is a Condition

NCT02961764_inc_task1

Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please typing these entity words according to sentence: Emergency Department ( ED ), Acute Bacterial Skin and Skin Structure Infections, ABSSSI, gram - positive, infection Options: Condition, Measurement, Visit, Qualifier

[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]

Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.

[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]

[ "Measurement", "Visit", "Qualifier", "Condition" ]

Emergency Department ( ED ), Acute Bacterial Skin and Skin Structure Infections, ABSSSI, gram - positive, infection

NCT02961764_inc_task2

Sentence: Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "B-Visit", "I-Visit", "I-Visit", "I-Visit", "I-Visit", "O", "O", "O", "O", "O", "O", "B-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "I-Measurement", "O", "B-Measurement", "O", "O", "O", "O", "O", "B-Qualifier", "I-Qualifier", "I-Qualifier", "B-Condition", "O", "O" ]

Presents to the Emergency Department (ED) and meets the clinical definition for Acute Bacterial Skin and Skin Structure Infections (ABSSSI) Known or suspected gram-positive infection.

[ "Presents", "to", "the", "Emergency", "Department", "(", "ED", ")", "and", "meets", "the", "clinical", "definition", "for", "Acute", "Bacterial", "Skin", "and", "Skin", "Structure", "Infections", "(", "ABSSSI", ")", "\n", "Known", "or", "suspected", "gram", "-", "positive", "infection", ".", "\n" ]

[ "Measurement", "Visit", "Qualifier", "Condition" ]

collagenase-1 is a protein_molecule, differentiated monocyte - like ( U937 ) cells is a cell_line, AP-1 is a protein_molecule, upstream C / EBP - beta site is a DNA_domain_or_region

62476_task0

Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: DNA_domain_or_region, cell_line, protein_molecule

[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.

[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]

[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]

collagenase-1 is a protein_molecule, differentiated monocyte - like ( U937 ) cells is a cell_line, AP-1 is a protein_molecule, upstream C / EBP - beta site is a DNA_domain_or_region

62476_task1

Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please typing these entity words according to sentence: collagenase-1, differentiated monocyte - like ( U937 ) cells, AP-1, upstream C / EBP - beta site Options: DNA_domain_or_region, cell_line, protein_molecule

[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.

[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]

[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]

collagenase-1, differentiated monocyte - like ( U937 ) cells, AP-1, upstream C / EBP - beta site

62476_task2

Sentence: Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. Instructions: please extract entity words from the input sentence

[ "O", "O", "O", "B-protein_molecule", "O", "B-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "I-cell_line", "O", "O", "O", "B-protein_molecule", "O", "O", "B-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "I-DNA_domain_or_region", "O" ]

Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site.

[ "Transcriptional", "induction", "of", "collagenase-1", "in", "differentiated", "monocyte", "-", "like", "(", "U937", ")", "cells", "is", "regulated", "by", "AP-1", "and", "an", "upstream", "C", "/", "EBP", "-", "beta", "site", "." ]

[ "other_name", "DNA_domain_or_region", "DNA_family_or_group", "cell_line", "protein_molecule", "other_organic_compound", "(AND other_name other_name)", "(AND protein_family_or_group protein_family_or_group)", "DNA_molecule", "cell_type", "cell_component", "", "protein_family_or_group" ]

argón is a NORMALIZABLES, triamcinolona is a NORMALIZABLES, fluoresceína sódica is a NORMALIZABLES

213_task0

Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: NORMALIZABLES

[ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-NORMALIZABLES", "I-NORMALIZABLES", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ]

Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.

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[ "NORMALIZABLES" ]

argón is a NORMALIZABLES, triamcinolona is a NORMALIZABLES, fluoresceína sódica is a NORMALIZABLES

213_task1

Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please typing these entity words according to sentence: argón, triamcinolona, fluoresceína sódica Options: NORMALIZABLES

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Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.

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[ "NORMALIZABLES" ]

argón, triamcinolona, fluoresceína sódica

213_task2

Sentence: Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias. Instructions: please extract entity words from the input sentence

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Se estudió en nuestra consulta a un paciente varón de 57 años con antecedentes de diabetes mellitus tipo II, hipertensión y cardiopatía isquémica, por presentar retinopatía diabética proliferativa. Su agudeza visual era de 20/50 en el ojo derecho (OD) y de 20/25 en el izquierdo (OI). Previamente había sido tratado con panretinofotocoagulación con láser argón en ambos ojos, así como con vitrectomía pars plana y pelado de membrana limitante interna con inyección de triamcinolona intravítrea en OD debido a una hemorragia vítrea y edema macular difuso crónico. No se observaban membranas neovasculares residuales en el examen del fondo de ojo, pero si microaneurismas y hemorragias en el polo posterior de ambos ojos. En el ojo izquierdo, se observaban algunos AMIR en la zona temporal de la macula. Se realizó una angiografía fluoreseceínica usando 5 ml de fluoresceína sódica al 10%. Se observaron áreas isquémicas ecuatoriales y en el ojo izquierdo edema macular difuso y la AMIR, pero no se observaron membranas neovasculares. En este ojo y después de 8 minutos de angiograma, ocurrió un sangrado activo de la AMIR. El movimiento de los ojos dejó diferentes trazos de sangre en la cavidad vítrea. El sangrado fue breve y autolimitado, sin síntomas inicialmente. Poco después el paciente empezó a notar miodesospsias. Dos semanas más tarde, la hemorragia vítrea se resolvió sin consecuencias.

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[ "NORMALIZABLES" ]

radius fracture is an umlsterm, human is an umlsterm, injury is an umlsterm, woman is an umlsterm, post menopause is an umlsterm, osteoporosis is an umlsterm, calcium is an umlsterm, balance is an umlsterm, radius fracture is an umlsterm, classification is an umlsterm, treatment is an umlsterm, secondary is an umlsterm, exact is an umlsterm, K - wire is an umlsterm, screw is an umlsterm, forms is an umlsterm, posttraumatical is an umlsterm, joint is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, radius is an umlsterm, exact is an umlsterm, therapy is an umlsterm, University is an umlsterm, Berlin is an umlsterm, patients is an umlsterm, radius fractures is an umlsterm, dorsaly is an umlsterm, plate is an umlsterm, fractures is an umlsterm, bicortal is an umlsterm, bone is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, arthrosis is an umlsterm, X - ray is an umlsterm, evaluation is an umlsterm, assessment is an umlsterm

DerOrthopaede.90280853.eng.abstr_task0

Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .

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[ "umlsterm" ]

radius fracture is an umlsterm, human is an umlsterm, injury is an umlsterm, woman is an umlsterm, post menopause is an umlsterm, osteoporosis is an umlsterm, calcium is an umlsterm, balance is an umlsterm, radius fracture is an umlsterm, classification is an umlsterm, treatment is an umlsterm, secondary is an umlsterm, exact is an umlsterm, K - wire is an umlsterm, screw is an umlsterm, forms is an umlsterm, posttraumatical is an umlsterm, joint is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, radius is an umlsterm, exact is an umlsterm, therapy is an umlsterm, University is an umlsterm, Berlin is an umlsterm, patients is an umlsterm, radius fractures is an umlsterm, dorsaly is an umlsterm, plate is an umlsterm, fractures is an umlsterm, bicortal is an umlsterm, bone is an umlsterm, secondary is an umlsterm, dislocation is an umlsterm, arthrosis is an umlsterm, X - ray is an umlsterm, evaluation is an umlsterm, assessment is an umlsterm

DerOrthopaede.90280853.eng.abstr_task1

Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please typing these entity words according to sentence: radius fracture, human, injury, woman, post menopause, osteoporosis, calcium, balance, radius fracture, classification, treatment, secondary, exact, K - wire, screw, forms, posttraumatical, joint, secondary, dislocation, radius, exact, therapy, University, Berlin, patients, radius fractures, dorsaly, plate, fractures, bicortal, bone, secondary, dislocation, arthrosis, X - ray, evaluation, assessment Options: umlsterm

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The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .

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[ "umlsterm" ]

radius fracture, human, injury, woman, post menopause, osteoporosis, calcium, balance, radius fracture, classification, treatment, secondary, exact, K - wire, screw, forms, posttraumatical, joint, secondary, dislocation, radius, exact, therapy, University, Berlin, patients, radius fractures, dorsaly, plate, fractures, bicortal, bone, secondary, dislocation, arthrosis, X - ray, evaluation, assessment

DerOrthopaede.90280853.eng.abstr_task2

Sentence: The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores . Instructions: please extract entity words from the input sentence

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The distal radius fracture is the most common human skeletal injury . Predominantly woman in the 6th to 7th decade are found . There is a high correlation to the post menopause high turn over osteoporosis and its negative calcium balance . Due to the various multifactoral radius fracture combinations is a detailed classification with its correlated treatment important . The operative intervention in the past played a secondary roll . The newest concepts demand an exact reconstruction of the articulating surfaces through closed reposition and K-wire support , screw osteosynthesis , external fixation and its combinated forms . The posttraumatical joint changes with secondary palmar and dorsal dislocation of the radius base after reduction caused the exact therapy scheme with respect to the AO-classification to be developed . In the clinic and policlinic Oskar-Helene-Heim of the Free University in Berlin 213 patients were surgicly treated on distal radius fractures either from volar or dorsaly with a plate osteosynthesis between 1988-1998 . In cases of multidirectionional fractures with compression of the articular surfaces we combined a bicortal bone block or spongiosa to support and to avoid the secondary dislocation and thus arthrosis . The study was devided in three sections , beginning with the clinical inspection . Further followed the X-ray evaluation and the assessment of the DASH-scores .

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[ "umlsterm" ]

catheter is an umlsterm, therapy is an umlsterm, coronary artery disease is an umlsterm, techniques is an umlsterm, patients is an umlsterm, balloon angioplasty is an umlsterm, tissue is an umlsterm, stent is an umlsterm, implantation is an umlsterm, techniques is an umlsterm, prevention is an umlsterm, pharmacologic is an umlsterm, radiotherapeutic is an umlsterm, future is an umlsterm

ZfuerKardiologie.8087s052.eng.abstr_task0

Sentence: The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis . Instructions: please extract entities and their types from the input sentence, all entity types are in options Options: umlsterm

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The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis .

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[ "umlsterm" ]

catheter is an umlsterm, therapy is an umlsterm, coronary artery disease is an umlsterm, techniques is an umlsterm, patients is an umlsterm, balloon angioplasty is an umlsterm, tissue is an umlsterm, stent is an umlsterm, implantation is an umlsterm, techniques is an umlsterm, prevention is an umlsterm, pharmacologic is an umlsterm, radiotherapeutic is an umlsterm, future is an umlsterm

ZfuerKardiologie.8087s052.eng.abstr_task1

Sentence: The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis . Instructions: please typing these entity words according to sentence: catheter, therapy, coronary artery disease, techniques, patients, balloon angioplasty, tissue, stent, implantation, techniques, prevention, pharmacologic, radiotherapeutic, future Options: umlsterm

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The success of interventional catheter based therapy of coronary artery disease is still limited by a high rate of chronic restenosis . Using alternative mechanical techniques , there is increasing evidence that restenosis can be prevented in certain subsets of patients by optimized balloon angioplasty , DCA and stenting as well as by the combined approach of primary tissue removal with adjunctive stent implantation . This article summarizes the mechanical techniques of restenosis prevention or reduction that have been documented in controlled trials . Additional pharmacologic interventions and possibly genetic and/or radiotherapeutic approaches will be highly important for future reduction of restenosis .

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[ "umlsterm" ]