broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K33127281-001-05-6
|
ACH-000681
|
A549_LUNG
|
HTS002
| 1 | 1.625375 | -0.166101 | 0.142037 | 1.309614 | 0.068966 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000681
|
BRD-K33127281-001-05-6
|
ACH-000444
|
LU99_LUNG
|
HTS002
| 1 | 0.271713 | 1.808341 | 0.537616 | 0.854658 | 1.466525 | 2.26244 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000444
|
BRD-K33127281-001-05-6
|
ACH-000142
|
CAL29_URINARY_TRACT
|
HTS002
| 1 | 0.16324 | 4.914252 | 0.428673 | 0.865972 | 2.11348 | 2.290483 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000142
|
BRD-K33127281-001-05-6
|
ACH-000905
|
5637_URINARY_TRACT
|
HTS002
| 1 | 1.03166 | 0.300437 | -0.217937 | 1.020365 | 0.007928 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000905
|
BRD-K33127281-001-05-6
|
ACH-000680
|
SW948_LARGE_INTESTINE
|
HTS002
| 1 | 1.955441 | -0.653877 | 0.282499 | 1.233457 | 0.004597 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000680
|
BRD-K33127281-001-05-6
|
ACH-000921
|
NCIH1339_LUNG
|
HTS002
| 1 | 1.486182 | -0.243664 | 0.047236 | 1.194965 | 0.012512 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000921
|
BRD-K33127281-001-05-6
|
ACH-000954
|
HEC1A_ENDOMETRIUM
|
HTS002
| 1 | 2.134702 | -0.53799 | 0.178351 | 1.170845 | 0.000869 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000954
|
BRD-K33127281-001-05-6
|
ACH-000280
|
SNU840_OVARY
|
HTS002
| 1 | 1.837208 | -0.373401 | 0.272935 | 1.209557 | 0.002083 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000280
|
BRD-K33127281-001-05-6
|
ACH-000012
|
HCC827_LUNG
|
HTS002
| 1 | 1.394837 | -0.193789 | 0.018913 | 1.192445 | 0.059107 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000012
|
BRD-K33127281-001-05-6
|
ACH-000098
|
GAMG_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.711211 | -0.169398 | -0.020328 | 1.391995 | 0.000042 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000098
|
BRD-K33127281-001-05-6
|
ACH-000589
|
NCIH1437_LUNG
|
HTS002
| 1 | 1.328318 | -0.201147 | 0.037828 | 1.155507 | 0.04438 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000589
|
BRD-K33127281-001-05-6
|
ACH-000738
|
GB1_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.052544 | -0.408566 | 0.248015 | 1.487438 | 0.048679 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000738
|
BRD-K33127281-001-05-6
|
ACH-000837
|
NCIH322_LUNG
|
HTS002
| 1 | 1.418479 | -0.902451 | 0.211881 | 1.178993 | 0.03801 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000837
|
BRD-K33127281-001-05-6
|
ACH-000967
|
SNUC2A_LARGE_INTESTINE
|
HTS002
| 1 | 0.687205 | 2.708607 | 0.078757 | 0.915635 | 0.730197 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000967
|
BRD-K33127281-001-05-6
|
ACH-000662
|
CORL23_LUNG
|
HTS002
| 1 | 2.257538 | -0.416889 | 0.149745 | 1.351193 | 0.004112 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000662
|
BRD-K33127281-001-05-6
|
ACH-000537
|
SNU761_LIVER
|
HTS002
| 1 | 1.550714 | -4.949394 | 0.138502 | 1.278437 | 0.082482 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000537
|
BRD-K33127281-001-05-6
|
ACH-000427
|
NCIN87_STOMACH
|
HTS002
| 1 | 0.654995 | 3.810969 | -0.018745 | 0.885811 | 0.402823 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000427
|
BRD-K33127281-001-05-6
|
ACH-000774
|
RERFLCAD2_LUNG
|
HTS002
| 1 | 1.378145 | -0.04357 | -0.069793 | 1.178849 | 0.006453 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000774
|
BRD-K33127281-001-05-6
|
ACH-000624
|
HCC1806_BREAST
|
HTS002
| 1 | 0.373766 | 3.983773 | 0.387139 | 0.823479 | 0.648709 | 0.916446 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000624
|
BRD-K33127281-001-05-6
|
ACH-000888
|
NCIH1793_LUNG
|
HTS002
| 1 | 2.041542 | 0.21155 | -0.045578 | 1.417039 | 0.619782 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000888
|
BRD-K33127281-001-05-6
|
ACH-000449
|
MESSA_SOFT_TISSUE
|
HTS002
| 1 | 2.780434 | -2.165218 | 0.085979 | 1.148318 | 0.001254 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000449
|
BRD-K33127281-001-05-6
|
ACH-000813
|
T3M10_LUNG
|
HTS002
| 1 | 1.444167 | -13.744987 | 0.023299 | 1.167276 | 0.023591 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000813
|
BRD-K33127281-001-05-6
|
ACH-000311
|
NCIH2122_LUNG
|
HTS002
| 1 | 0.599807 | 5.543405 | 0.064759 | 0.916146 | 1.309001 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000311
|
BRD-K33127281-001-05-6
|
ACH-000849
|
MDAMB468_BREAST
|
HTS002
| 1 | 2.061747 | -2.706735 | 0.28396 | 1.536697 | 0.082395 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000849
|
BRD-K33127281-001-05-6
|
ACH-000868
|
HCC1195_LUNG
|
HTS002
| 1 | 2.105777 | -3.342219 | 0.386933 | 1.280561 | 0.007159 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000868
|
BRD-K33127281-001-05-6
|
ACH-000978
|
EN_ENDOMETRIUM
|
HTS002
| 1 | 1.79769 | -0.228301 | 0.081649 | 1.264255 | 0.00268 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000978
|
BRD-K33127281-001-05-6
|
ACH-000408
|
TE5_OESOPHAGUS
|
HTS002
| 1 | 1.382184 | -0.315734 | 0.127301 | 1.1743 | 0.040263 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000408
|
BRD-K33127281-001-05-6
|
ACH-000344
|
SNU668_STOMACH
|
HTS002
| 1 | 1.861789 | -0.163629 | 0.062094 | 1.335244 | 0.004298 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000344
|
BRD-K33127281-001-05-6
|
ACH-000161
|
CORL105_LUNG
|
HTS002
| 1 | 1.733337 | -0.600296 | 0.138958 | 1.259763 | 0.015745 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000161
|
BRD-K33127281-001-05-6
|
ACH-000835
|
GCT_SOFT_TISSUE
|
HTS002
| 1 | 1.570585 | -0.782699 | 0.281011 | 1.42049 | 0.933621 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000835
|
BRD-K33127281-001-05-6
|
ACH-000819
|
LN18_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.971496 | 0.979602 | -0.270345 | 0.990054 | 0.350648 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000819
|
BRD-K33127281-001-05-6
|
ACH-000062
|
RERFLCMS_LUNG
|
HTS002
| 1 | 1.412689 | -0.490296 | 0.012834 | 1.146443 | 0.013873 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000062
|
BRD-K33127281-001-05-6
|
ACH-000473
|
RT112_URINARY_TRACT
|
HTS002
| 1 | 1.352976 | -1.247015 | 0.129793 | 1.195242 | 0.131172 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000473
|
BRD-K33127281-001-05-6
|
ACH-000176
|
LOUNH91_LUNG
|
HTS002
| 1 | 1.733587 | -2.081391 | 0.163641 | 1.19987 | 0.00857 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000176
|
BRD-K33127281-001-05-6
|
ACH-000445
|
KNS60_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 1.680155 | -0.925433 | 0.410826 | 1.411124 | 0.221101 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000445
|
BRD-K33127281-001-05-6
|
ACH-000331
|
ISTMES2_PLEURA
|
HTS002
| 1 | 0.536891 | 4.050193 | 0.166436 | 0.860946 | 0.542712 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000331
|
BRD-K33127281-001-05-6
|
ACH-000163
|
SW579_THYROID
|
HTS002
| 1 | 1.24795 | -7.30931 | 0.158185 | 1.115293 | 0.055619 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000163
|
BRD-K33127281-001-05-6
|
ACH-000768
|
MDAMB231_BREAST
|
HTS002
| 1 | 1.318101 | -0.271629 | -0.176092 | 1.251773 | 19.300794 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000768
|
BRD-K33127281-001-05-6
| null | null |
HTS002
| 1 | 0.910282 | -2.450803 | -0.070354 | 0.957311 | 0.061781 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| false |
ACH-001078_FAILED_STR
|
BRD-K33127281-001-05-6
|
ACH-000778
|
HSC3_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.342139 | 2.336441 | 0.509457 | 0.891104 | 2.026726 | 3.319657 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000778
|
BRD-K33127281-001-05-6
|
ACH-000881
|
MELJUSO_SKIN
|
HTS002
| 1 | 0.65034 | 1.582031 | 0.151422 | 0.947793 | 2.511834 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000881
|
BRD-K33127281-001-05-6
|
ACH-000521
|
NCIH2030_LUNG
|
HTS002
| 1 | 1.648779 | -0.465782 | 0.325141 | 1.35085 | 0.127361 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000521
|
BRD-K33127281-001-05-6
|
ACH-000696
|
OVCAR8_OVARY
|
HTS002
| 1 | 1.368782 | -2.818207 | 0.385673 | 1.306522 | 1.94995 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000696
|
BRD-K33127281-001-05-6
|
ACH-000972
|
HEC151_ENDOMETRIUM
|
HTS002
| 1 | 0.364076 | 3.391952 | 0.240828 | 0.909583 | 2.523339 | 3.704633 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000972
|
BRD-K33127281-001-05-6
|
ACH-000242
|
RT4_URINARY_TRACT
|
HTS002
| 1 | 1.81617 | -0.90745 | 0.218992 | 1.417289 | 0.087396 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000242
|
BRD-K33127281-001-05-6
|
ACH-000087
|
SKES1_BONE
|
HTS002
| 1 | 1.458118 | -0.285376 | 0.045762 | 1.150043 | 0.004324 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000087
|
BRD-K33127281-001-05-6
|
ACH-000356
|
MKN45_STOMACH
|
HTS002
| 1 | 2.377589 | -0.242005 | 0.192605 | 1.550266 | 0.012021 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000356
|
BRD-K33127281-001-05-6
|
ACH-000625
|
HEP3B217_LIVER
|
HTS002
| 1 | 2.448313 | -0.658041 | -0.048666 | 1.355394 | 0.004684 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000625
|
BRD-K33127281-001-05-6
|
ACH-000613
|
HOS_BONE
|
HTS002
| 1 | 1.664101 | -0.354602 | 0.293379 | 1.330474 | 0.075582 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000613
|
BRD-K33127281-001-05-6
|
ACH-000976
|
HUCCT1_BILIARY_TRACT
|
HTS002
| 1 | 1.522784 | -0.256875 | 0.083329 | 1.188553 | 0.006401 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000976
|
BRD-K33127281-001-05-6
|
ACH-001075
|
NCIH292_LUNG
|
HTS002
| 1 | 1.29184 | 0.011919 | -0.054366 | 1.146239 | 0.054134 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-001075
|
BRD-K33127281-001-05-6
|
ACH-000261
|
RERFLCAI_LUNG
|
HTS002
| 1 | 1.245995 | -0.366452 | 0.076886 | 1.093979 | 0.015243 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000261
|
BRD-K33127281-001-05-6
|
ACH-000957
|
LS180_LARGE_INTESTINE
|
HTS002
| 1 | 1.946985 | -0.225386 | 0.086973 | 1.362807 | 0.007709 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000957
|
BRD-K33127281-001-05-6
|
ACH-000099
|
SIMA_AUTONOMIC_GANGLIA
|
HTS002
| 1 | 1.224586 | -0.184865 | -0.025252 | 1.057845 | 0.00018 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000099
|
BRD-K33127281-001-05-6
|
ACH-000783
|
CAMA1_BREAST
|
HTS002
| 1 | 1.602748 | -0.876671 | 0.081946 | 1.093298 | 0.001922 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000783
|
BRD-K33127281-001-05-6
|
ACH-000573
|
MDAMB436_BREAST
|
HTS002
| 1 | 0.862467 | 1.59873 | -0.127294 | 0.951901 | 0.336745 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000573
|
BRD-K33127281-001-05-6
|
ACH-000852
|
NCIH1435_LUNG
|
HTS002
| 1 | 2.054251 | -0.213077 | 0.09365 | 1.258971 | 0.000266 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000852
|
BRD-K33127281-001-05-6
|
ACH-000461
|
SNU1196_BILIARY_TRACT
|
HTS002
| 1 | 2.176736 | -1.332222 | 0.308759 | 1.237718 | 0.004094 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000461
|
BRD-K33127281-001-05-6
|
ACH-000420
|
SNU449_LIVER
|
HTS002
| 1 | 0.874694 | 4.146788 | -0.049175 | 0.951919 | 0.24149 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000420
|
BRD-K33127281-001-05-6
|
ACH-000694
|
TE9_OESOPHAGUS
|
HTS002
| 1 | 0.606372 | 7.321323 | 0.072609 | 0.859603 | 0.313924 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000694
|
BRD-K33127281-001-05-6
|
ACH-000845
|
NCIH1373_LUNG
|
HTS002
| 1 | 0.091721 | 4.060877 | 0.404882 | 0.966944 | 7.511547 | 7.895918 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000845
|
BRD-K33127281-001-05-6
|
ACH-000563
|
EBC1_LUNG
|
HTS002
| 1 | 0.314754 | 1.387623 | 0.482875 | 0.804164 | 0.634284 | 1.297316 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000563
|
BRD-K33127281-001-05-6
|
ACH-000665
|
SKMES1_LUNG
|
HTS002
| 1 | 0.460859 | 1.555034 | 0.205813 | 0.933978 | 3.402478 | 17.508578 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000665
|
BRD-K33127281-001-05-6
|
ACH-000467
|
HCC56_LARGE_INTESTINE
|
HTS002
| 1 | 1.772622 | -0.516382 | 0.068899 | 1.374212 | 0.065319 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000467
|
BRD-K33127281-001-05-6
|
ACH-000201
|
A204_SOFT_TISSUE
|
HTS002
| 1 | 0.543603 | 0.945169 | 0.157864 | 0.842074 | 0.363235 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000201
|
BRD-K33127281-001-05-6
|
ACH-000189
|
RCC10RGB_KIDNEY
|
HTS002
| 1 | 1.391358 | -1.98444 | 0.462662 | 1.299892 | 1.041035 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000189
|
BRD-K33127281-001-05-6
|
ACH-000791
|
RERFLCAD1_LUNG
|
HTS002
| 1 | 1.654848 | -0.714781 | 0.476317 | 1.157051 | 0.004697 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000791
|
BRD-K33127281-001-05-6
|
ACH-000367
|
NCIH226_LUNG
|
HTS002
| 1 | 1.186685 | -4.731193 | 0.194983 | 1.150891 | 1.555828 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000367
|
BRD-K33127281-001-05-6
|
ACH-001190
|
SKMEL2_SKIN
|
HTS002
| 1 | 1.602579 | -0.416945 | 0.159648 | 1.218678 | 0.013324 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-001190
|
BRD-K33127281-001-05-6
|
ACH-000244
|
DKMG_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.668741 | 0.747682 | -0.02838 | 0.868502 | 0.225537 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000244
|
BRD-K33127281-001-05-6
|
ACH-000713
|
CAOV3_OVARY
|
HTS002
| 1 | 0.647421 | 1.470374 | 0.253418 | 0.921629 | 1.19089 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000713
|
BRD-K33127281-001-05-6
|
ACH-000672
|
IALM_LUNG
|
HTS002
| 1 | 1.447032 | 0.070768 | -0.012519 | 1.279655 | 0.000052 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000672
|
BRD-K33127281-001-05-6
|
ACH-000875
|
NCIH2347_LUNG
|
HTS002
| 1 | 1.838603 | -2.430108 | 0.317015 | 1.47153 | 0.142978 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000875
|
BRD-K33127281-001-05-6
|
ACH-000423
|
SKMEL3_SKIN
|
HTS002
| 1 | 1.334171 | -0.312806 | 0.070804 | 1.127355 | 0.012523 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000423
|
BRD-K33127281-001-05-6
|
ACH-000553
|
SQ1_LUNG
|
HTS002
| 1 | 1.411684 | -1.169107 | 0.20277 | 1.189438 | 0.052925 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000553
|
BRD-K33127281-001-05-6
|
ACH-000834
|
UMUC1_URINARY_TRACT
|
HTS002
| 1 | 1.777125 | -0.220004 | 0.111357 | 1.333573 | 0.018977 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000834
|
BRD-K33127281-001-05-6
|
ACH-000252
|
LS1034_LARGE_INTESTINE
|
HTS002
| 1 | 2.388324 | -0.217343 | 0.213488 | 1.618768 | 0.026153 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000252
|
BRD-K33127281-001-05-6
|
ACH-000123
|
COV434_OVARY
|
HTS002
| 1 | 2.95502 | -1.214842 | 0.145172 | 1.256395 | 0.001789 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000123
|
BRD-K33127281-001-05-6
|
ACH-000329
|
CCFSTTG1_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 1.003485 | 1.051608 | -0.192439 | 1.001426 | 0.190702 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000329
|
BRD-K33127281-001-05-6
|
ACH-000717
|
COLO680N_OESOPHAGUS
|
HTS002
| 1 | 0.453641 | 8.177727 | 0.046122 | 0.931318 | 2.952632 | 3.949188 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000717
|
BRD-K33127281-001-05-6
|
ACH-000669
|
SW900_LUNG
|
HTS002
| 1 | 0.672417 | 5.387429 | 0.014903 | 0.854564 | 0.134565 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000669
|
BRD-K33127281-001-05-6
|
ACH-000764
|
SH10TC_STOMACH
|
HTS002
| 1 | 0.417161 | 4.913605 | 0.188687 | 0.912282 | 2.321612 | 3.347201 |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000764
|
BRD-K33127281-001-05-6
|
ACH-000288
|
BT549_BREAST
|
HTS002
| 1 | 1.61628 | -8.046337 | 0.314792 | 1.386623 | 0.268838 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000288
|
BRD-K33127281-001-05-6
|
ACH-000415
|
BICR6_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 1.369942 | -10.212669 | 0.14264 | 1.132857 | 0.019911 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000415
|
BRD-K33127281-001-05-6
|
ACH-000228
|
BICR31_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 1.640067 | -0.9647 | 0.329034 | 1.2369 | 0.021495 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000228
|
BRD-K33127281-001-05-6
|
ACH-000977
|
LNCAPCLONEFGC_PROSTATE
|
HTS002
| 1 | 0.703817 | -0.109484 | -0.156482 | 0.854399 | 0.057046 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000977
|
BRD-K33127281-001-05-6
|
ACH-000397
|
TEN_ENDOMETRIUM
|
HTS002
| 1 | 2.160185 | 0.080152 | -0.027305 | 1.537584 | 0.499224 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000397
|
BRD-K33127281-001-05-6
|
ACH-000565
|
RCM1_LARGE_INTESTINE
|
HTS002
| 1 | 1.670617 | -1.272527 | 0.2837 | 1.205691 | 0.011762 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000565
|
BRD-K33127281-001-05-6
|
ACH-000209
|
SNU1079_BILIARY_TRACT
|
HTS002
| 1 | 2.228419 | 0.241141 | -0.035313 | 1.086071 | 7,759.822632 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000209
|
BRD-K33127281-001-05-6
|
ACH-000927
|
BT474_BREAST
|
HTS002
| 1 | 1.531144 | -3.158365 | 0.365878 | 1.239413 | 0.048443 | null |
adapalene
|
retinoid receptor agonist
|
RARA, RARB, RARG, RXRA, RXRB, RXRG
|
dermatology
|
acne vulgaris (AV)
|
COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O, COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
|
Launched
| true |
ACH-000927
|
BRD-K19388745-003-01-7
|
ACH-000879
|
MFE296_ENDOMETRIUM
|
HTS002
| 1 | 1.960588 | -0.165716 | 0.073318 | 1.45643 | 0.041521 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000879
|
BRD-K19388745-003-01-7
|
ACH-000320
|
PSN1_PANCREAS
|
HTS002
| 1 | 2.051972 | -0.477016 | 0.47152 | 1.400158 | 0.01863 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000320
|
BRD-K19388745-003-01-7
|
ACH-001145
|
OC316_OVARY
|
HTS002
| 1 | 0.473975 | 2.458487 | 0.044829 | 0.958008 | 4.920965 | 16.373897 |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-001145
|
BRD-K19388745-003-01-7
|
ACH-000873
|
KYSE270_OESOPHAGUS
|
HTS002
| 1 | 1.737132 | 0.14177 | -0.171518 | 1.314984 | 0.667856 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000873
|
BRD-K19388745-003-01-7
|
ACH-000855
|
KYSE150_OESOPHAGUS
|
HTS002
| 1 | 2.031766 | -0.227033 | 0.160743 | 1.470629 | 0.033347 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000855
|
BRD-K19388745-003-01-7
|
ACH-000913
|
ESS1_ENDOMETRIUM
|
HTS002
| 1 | 1.279408 | -1.951962 | 0.175837 | 1.155614 | 0.135771 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000913
|
BRD-K19388745-003-01-7
|
ACH-000558
|
A172_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.329459 | -0.317185 | 0.277085 | 1.693785 | 0.10847 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000558
|
BRD-K19388745-003-01-7
|
ACH-000488
|
TE11_OESOPHAGUS
|
HTS002
| 1 | 1.580479 | -0.073461 | 0.008246 | 1.277719 | 0.023823 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000488
|
BRD-K19388745-003-01-7
|
ACH-000832
|
CAL27_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 2.235724 | -0.186315 | 0.291961 | 1.528679 | 0.014789 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000832
|
BRD-K19388745-003-01-7
|
ACH-000781
|
NCIH2023_LUNG
|
HTS002
| 1 | 1.972611 | 0.082896 | -0.080372 | 1.609278 | 0.000141 | null |
colforsin-daproate
|
adenylyl cyclase activator
| null | null | null |
CN(C)CCC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]2(C)[C@@H](O)CCC(C)(C)[C@H]12)C=C
|
Launched
| true |
ACH-000781
|
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