broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K11640013-236-10-1
|
ACH-000791
|
RERFLCAD1_LUNG
|
HTS002
| 1 | 2.485495 | -0.109882 | 0.176008 | 1.628032 | 0.004298 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000791
|
BRD-K11640013-236-10-1
|
ACH-000367
|
NCIH226_LUNG
|
HTS002
| 1 | 1.772841 | -0.394182 | 0.175403 | 1.360846 | 0.050674 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000367
|
BRD-K11640013-236-10-1
|
ACH-001190
|
SKMEL2_SKIN
|
HTS002
| 1 | 2.0683 | 0.003855 | -0.073796 | 1.43774 | 10,306,495,996,652,901,000,000,000,000,000,000,000,000 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-001190
|
BRD-K11640013-236-10-1
|
ACH-000244
|
DKMG_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.005448 | -0.130885 | 0.083902 | 1.428036 | 0.007355 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000244
|
BRD-K11640013-236-10-1
|
ACH-000713
|
CAOV3_OVARY
|
HTS002
| 1 | 1.704969 | -0.405419 | 0.238329 | 1.291292 | 0.025373 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000713
|
BRD-K11640013-236-10-1
|
ACH-000672
|
IALM_LUNG
|
HTS002
| 1 | 2.536702 | -0.282264 | 0.1872 | 1.546499 | 0.00698 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000672
|
BRD-K11640013-236-10-1
|
ACH-000875
|
NCIH2347_LUNG
|
HTS002
| 1 | 3.284545 | 0.018072 | -0.014244 | 1.459562 | 112,458,463,934,915,000,000,000,000,000,000 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000875
|
BRD-K11640013-236-10-1
|
ACH-000423
|
SKMEL3_SKIN
|
HTS002
| 1 | 1.539026 | -0.132392 | -0.014921 | 1.334238 | 3.577379 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000423
|
BRD-K11640013-236-10-1
|
ACH-000553
|
SQ1_LUNG
|
HTS002
| 1 | 1.583127 | -0.033409 | 0.008907 | 1.350283 | 16,320.564047 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000553
|
BRD-K11640013-236-10-1
|
ACH-000834
|
UMUC1_URINARY_TRACT
|
HTS002
| 1 | 1.768868 | -0.065418 | -0.077626 | 1.352494 | 0.005996 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000834
|
BRD-K11640013-236-10-1
|
ACH-000252
|
LS1034_LARGE_INTESTINE
|
HTS002
| 1 | 2.300034 | -0.380468 | 0.070909 | 1.48384 | 0.013783 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000252
|
BRD-K11640013-236-10-1
|
ACH-000329
|
CCFSTTG1_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.088251 | -0.065571 | -0.022396 | 1.512019 | 0.012696 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000329
|
BRD-K11640013-236-10-1
|
ACH-000669
|
SW900_LUNG
|
HTS002
| 1 | 1.72115 | -0.402168 | -0.018646 | 1.314975 | 0.034405 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000669
|
BRD-K11640013-236-10-1
|
ACH-000764
|
SH10TC_STOMACH
|
HTS002
| 1 | 1.657517 | -0.14858 | -0.086188 | 1.351102 | 0.203126 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000764
|
BRD-K11640013-236-10-1
|
ACH-000288
|
BT549_BREAST
|
HTS002
| 1 | 2.330991 | 0.026467 | -0.017626 | 1.565861 | 7,079.948567 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000288
|
BRD-K11640013-236-10-1
|
ACH-000228
|
BICR31_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 2.131533 | 0.009276 | -0.029338 | 1.54103 | 977.370434 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000228
|
BRD-K11640013-236-10-1
|
ACH-000977
|
LNCAPCLONEFGC_PROSTATE
|
HTS002
| 1 | 0.526382 | -0.72343 | -0.072771 | 0.91068 | 0.002493 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000977
|
BRD-K11640013-236-10-1
|
ACH-000397
|
TEN_ENDOMETRIUM
|
HTS002
| 1 | 2.339336 | -0.054803 | -0.062163 | 1.644467 | 0.019614 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000397
|
BRD-K11640013-236-10-1
|
ACH-000565
|
RCM1_LARGE_INTESTINE
|
HTS002
| 1 | 1.166093 | -0.106996 | -0.014614 | 1.144938 | 6,901,838.303 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000565
|
BRD-K11640013-236-10-1
|
ACH-000209
|
SNU1079_BILIARY_TRACT
|
HTS002
| 1 | 1.828702 | -0.081601 | -0.071638 | 1.381535 | 0.010889 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000209
|
BRD-K11640013-236-10-1
|
ACH-000927
|
BT474_BREAST
|
HTS002
| 1 | 1.515865 | 0.22957 | -0.003009 | 1.208778 | 0.496295 | null |
sulfamethazine
|
PABA antagonist
| null |
gastroenterology
|
enteritis, enteritis
|
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
|
Launched
| true |
ACH-000927
|
BRD-K53123955-001-10-5
|
ACH-000879
|
MFE296_ENDOMETRIUM
|
HTS002
| 1 | 2.707382 | -0.014084 | -0.003647 | 1.870691 | 1.322929 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000879
|
BRD-K53123955-001-10-5
|
ACH-000320
|
PSN1_PANCREAS
|
HTS002
| 1 | 1.744038 | 0.071396 | -0.055168 | 1.426763 | 0.001179 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000320
|
BRD-K53123955-001-10-5
|
ACH-001145
|
OC316_OVARY
|
HTS002
| 1 | 2.24898 | -0.41849 | 0.24352 | 1.368231 | 0.005199 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-001145
|
BRD-K53123955-001-10-5
|
ACH-000873
|
KYSE270_OESOPHAGUS
|
HTS002
| 1 | 1.508895 | -0.0156 | -0.02481 | 1.252389 | 0.027678 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000873
|
BRD-K53123955-001-10-5
|
ACH-000855
|
KYSE150_OESOPHAGUS
|
HTS002
| 1 | 2.02555 | -0.10306 | 0.050079 | 1.436475 | 0.004012 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000855
|
BRD-K53123955-001-10-5
|
ACH-000913
|
ESS1_ENDOMETRIUM
|
HTS002
| 1 | 2.363238 | -0.195478 | 0.114048 | 1.570141 | 0.012759 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000913
|
BRD-K53123955-001-10-5
|
ACH-000558
|
A172_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.574821 | 0.105086 | -0.112184 | 1.699321 | 0.693897 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000558
|
BRD-K53123955-001-10-5
|
ACH-000593
|
BC3C_URINARY_TRACT
|
HTS002
| 1 | 1.870351 | -0.324962 | 0.032906 | 1.475219 | 0.154306 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000593
|
BRD-K53123955-001-10-5
|
ACH-000488
|
TE11_OESOPHAGUS
|
HTS002
| 1 | 1.748652 | -0.190095 | 0.333631 | 1.312666 | 0.012039 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000488
|
BRD-K53123955-001-10-5
|
ACH-000832
|
CAL27_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 2.210649 | -0.023077 | 0.000251 | 1.553166 | 0.000043 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000832
|
BRD-K53123955-001-10-5
|
ACH-000781
|
NCIH2023_LUNG
|
HTS002
| 1 | 2.061427 | -0.143665 | 0.049854 | 1.641572 | 1.679818 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000781
|
BRD-K53123955-001-10-5
|
ACH-000833
|
RH30_SOFT_TISSUE
|
HTS002
| 1 | 2.477592 | -0.129669 | 0.013741 | 1.532508 | 0.000813 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000833
|
BRD-K53123955-001-10-5
|
ACH-000137
|
8MGBA_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 1.866521 | -0.370116 | 0.529015 | 1.303173 | 0.009695 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000137
|
BRD-K53123955-001-10-5
|
ACH-000632
|
HS944T_SKIN
|
HTS002
| 1 | 2.480804 | 0.035248 | 0.034747 | 1.772074 | 0.006847 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000632
|
BRD-K53123955-001-10-5
|
ACH-000319
|
MPP89_PLEURA
|
HTS002
| 1 | 2.014639 | -0.01168 | 0.004628 | 1.506747 | 0.064391 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000319
|
BRD-K53123955-001-10-5
|
ACH-000630
|
YD8_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 2.390916 | -0.457916 | 0.190163 | 1.452113 | 0.008887 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000630
|
BRD-K53123955-001-10-5
|
ACH-000266
|
SNU213_PANCREAS
|
HTS002
| 1 | 2.431625 | -0.090547 | 0.03832 | 1.574247 | 0.000871 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000266
|
BRD-K53123955-001-10-5
|
ACH-000047
|
GCIY_STOMACH
|
HTS002
| 1 | 1.660206 | -0.239893 | 0.062325 | 1.240777 | 0.006025 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000047
|
BRD-K53123955-001-10-5
|
ACH-000273
|
SF539_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 1.55313 | 0.070194 | -0.012957 | 1.318064 | 0.001009 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000273
|
BRD-K53123955-001-10-5
|
ACH-000682
|
SNU1066_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.774442 | 0.246971 | 0.024044 | 0.90035 | 0.224858 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000682
|
BRD-K53123955-001-10-5
|
ACH-000846
|
FADU_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.823901 | 0.350784 | 0.061627 | 0.882616 | 0.007011 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000846
|
BRD-K53123955-001-10-5
|
ACH-000804
|
NB1_AUTONOMIC_GANGLIA
|
HTS002
| 1 | 0.924692 | 1.036491 | 0.056449 | 0.97252 | 0.296656 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000804
|
BRD-K53123955-001-10-5
|
ACH-000609
|
SF126_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.735008 | -0.007323 | -0.044528 | 0.870048 | 0.000412 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000609
|
BRD-K53123955-001-10-5
|
ACH-000974
|
SNGM_ENDOMETRIUM
|
HTS002
| 1 | 2.423668 | -0.395213 | -0.023605 | 1.542899 | 0.016243 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000974
|
BRD-K53123955-001-10-5
|
ACH-000987
|
MEWO_SKIN
|
HTS002
| 1 | 1.457721 | -0.174383 | 0.002297 | 1.190766 | 0.010164 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000987
|
BRD-K53123955-001-10-5
|
ACH-000787
|
LXF289_LUNG
|
HTS002
| 1 | 1.344528 | 0.002645 | -0.027467 | 1.17227 | 0.07603 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000787
|
BRD-K53123955-001-10-5
|
ACH-000561
|
TT_OESOPHAGUS
|
HTS002
| 1 | 1.152161 | 0.021652 | -0.15535 | 1.081481 | 0.000109 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000561
|
BRD-K53123955-001-10-5
|
ACH-000212
|
CAL120_BREAST
|
HTS002
| 1 | 2.021471 | -0.316988 | 0.233437 | 1.316818 | 0.003991 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000212
|
BRD-K53123955-001-10-5
|
ACH-000753
|
JMSU1_URINARY_TRACT
|
HTS002
| 1 | 1.371387 | -0.008593 | -0.140623 | 1.263536 | 113,723,704,752,167,000,000,000,000,000,000,000,000,000,000 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000753
|
BRD-K53123955-001-10-5
|
ACH-000305
|
ECGI10_OESOPHAGUS
|
HTS002
| 1 | 1.903529 | -0.10301 | 0.081344 | 1.342746 | 0.000595 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000305
|
BRD-K53123955-001-10-5
|
ACH-000250
|
KMRC20_KIDNEY
|
HTS002
| 1 | 1.100093 | -0.069316 | -0.02611 | 1.053944 | 0.758434 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000250
|
BRD-K53123955-001-10-5
|
ACH-000856
|
CAL51_BREAST
|
HTS002
| 1 | 2.064906 | -0.212415 | 0.302782 | 1.539362 | 0.089221 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000856
|
BRD-K53123955-001-10-5
|
ACH-000046
|
ACHN_KIDNEY
|
HTS002
| 1 | 1.694481 | -0.325615 | 0.113187 | 1.279767 | 0.018379 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000046
|
BRD-K53123955-001-10-5
|
ACH-000878
|
HCC15_LUNG
|
HTS002
| 1 | 1.555522 | -0.550508 | -0.037089 | 1.23791 | 0.035006 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000878
|
BRD-K53123955-001-10-5
|
ACH-000766
|
NCIH1648_LUNG
|
HTS002
| 1 | 1.265474 | 0.123361 | -0.037297 | 1.165402 | 0.001181 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000766
|
BRD-K53123955-001-10-5
|
ACH-000666
|
NCIH1355_LUNG
|
HTS002
| 1 | 2.49382 | 0.053356 | 0.016953 | 1.657449 | 7.292999 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000666
|
BRD-K53123955-001-10-5
|
ACH-000014
|
HS294T_SKIN
|
HTS002
| 1 | 2.28851 | -0.104537 | 0.086005 | 1.539908 | 0.003209 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000014
|
BRD-K53123955-001-10-5
|
ACH-000701
|
RMUGS_OVARY
|
HTS002
| 1 | 2.207268 | -0.080481 | 0.010023 | 1.611982 | 0.110649 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000701
|
BRD-K53123955-001-10-5
|
ACH-000884
|
MDAMB435S_SKIN
|
HTS002
| 1 | 1.668921 | -0.270952 | 0.189644 | 1.339216 | 0.088054 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000884
|
BRD-K53123955-001-10-5
|
ACH-000037
|
S117_SOFT_TISSUE
|
HTS002
| 1 | 2.103559 | -0.231746 | 0.009435 | 1.641621 | 0.372801 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000037
|
BRD-K53123955-001-10-5
|
ACH-000504
|
SNB75_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 3.66152 | -0.296109 | -0.106941 | 1.692719 | 0.001344 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000504
|
BRD-K53123955-001-10-5
|
ACH-000502
|
TCCPAN2_PANCREAS
|
HTS002
| 1 | 2.07636 | -0.495998 | 0.112163 | 1.202007 | 0.001378 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000502
|
BRD-K53123955-001-10-5
|
ACH-000886
|
NCIH2009_LUNG
|
HTS002
| 1 | 2.324391 | -0.148774 | 0.134296 | 1.500506 | 0.00238 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000886
|
BRD-K53123955-001-10-5
|
ACH-000035
|
NCIH1650_LUNG
|
HTS002
| 1 | 1.462305 | -0.052116 | 0.000799 | 1.226904 | 0.038444 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000035
|
BRD-K53123955-001-10-5
|
ACH-000661
|
WM1799_SKIN
|
HTS002
| 1 | 0.69353 | 2.235679 | 0.183833 | 0.90814 | 0.545862 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000661
|
BRD-K53123955-001-10-5
|
ACH-000843
|
HARA_LUNG
|
HTS002
| 1 | 2.784045 | -0.157436 | -0.006963 | 1.761572 | 0.010997 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000843
|
BRD-K53123955-001-10-5
|
ACH-000711
|
JIMT1_BREAST
|
HTS002
| 1 | 1.398846 | -0.310877 | -0.299486 | 1.267546 | 1.150726 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000711
|
BRD-K53123955-001-10-5
|
ACH-000232
|
U251MG_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.562903 | -0.059959 | 0.154965 | 1.729226 | 0.008248 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000232
|
BRD-K53123955-001-10-5
|
ACH-000060
|
PANC1005_PANCREAS
|
HTS002
| 1 | 1.589999 | 0.10926 | -0.120474 | 1.298396 | 0.062966 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000060
|
BRD-K53123955-001-10-5
|
ACH-000322
|
HT144_SKIN
|
HTS002
| 1 | 3.388119 | -0.023418 | -0.019176 | 2.15359 | 0.004304 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000322
|
BRD-K53123955-001-10-5
|
ACH-000736
|
SNU601_STOMACH
|
HTS002
| 1 | 1.509969 | -0.139957 | 0.108348 | 1.302001 | 1.241639 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000736
|
BRD-K53123955-001-10-5
|
ACH-000809
|
KYSE410_OESOPHAGUS
|
HTS002
| 1 | 1.356682 | -0.34253 | -0.034607 | 1.183251 | 0.095058 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000809
|
BRD-K53123955-001-10-5
|
ACH-000747
|
NCIH1703_LUNG
|
HTS002
| 1 | 1.864474 | -4.50504 | 0.760489 | 1.612622 | 0.591817 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000747
|
BRD-K53123955-001-10-5
|
ACH-000364
|
U2OS_BONE
|
HTS002
| 1 | 2.054799 | 0.198018 | 0.108153 | 1.574613 | 0.029465 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000364
|
BRD-K53123955-001-10-5
|
ACH-000679
|
OE19_OESOPHAGUS
|
HTS002
| 1 | 3.050024 | -0.302931 | 0.05567 | 1.542105 | 0.001559 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000679
|
BRD-K53123955-001-10-5
|
ACH-000985
|
LS411N_LARGE_INTESTINE
|
HTS002
| 1 | 1.634154 | -4.231559 | 0.504697 | 1.340365 | 0.111571 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000985
|
BRD-K53123955-001-10-5
|
ACH-000441
|
SH4_SKIN
|
HTS002
| 1 | 1.358168 | 0.101342 | -0.14609 | 1.244862 | 0.000034 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000441
|
BRD-K53123955-001-10-5
|
ACH-000620
|
JHH1_LIVER
|
HTS002
| 1 | 1.866826 | -0.079402 | 0.034254 | 1.438795 | 0.107227 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000620
|
BRD-K53123955-001-10-5
|
ACH-000853
|
NCIH661_LUNG
|
HTS002
| 1 | 1.858004 | -0.54425 | 0.02496 | 1.507049 | 0.217718 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000853
|
BRD-K53123955-001-10-5
|
ACH-000102
|
GMS10_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.189415 | -0.103964 | 0.202202 | 1.487228 | 0.002159 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000102
|
BRD-K53123955-001-10-5
| null | null |
HTS002
| 1 | 1.736157 | -0.191851 | 0.051084 | 1.266114 | 0.003279 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| false |
ACH-000925_FAILED_STR
|
BRD-K53123955-001-10-5
|
ACH-001239
|
WM2664_SKIN
|
HTS002
| 1 | 1.399898 | -0.602242 | 0.0178 | 1.053617 | 0.000823 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-001239
|
BRD-K53123955-001-10-5
|
ACH-001321
|
TT_THYROID
|
HTS002
| 1 | 0.995466 | 0.859678 | -0.954128 | 0.998259 | 0.250717 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-001321
|
BRD-K53123955-001-10-5
|
ACH-000279
|
EWS502_BONE
|
HTS002
| 1 | 2.435738 | -0.167172 | 0.139387 | 1.479733 | 0.001019 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000279
|
BRD-K53123955-001-10-5
|
ACH-000172
|
TM87_SOFT_TISSUE
|
HTS002
| 1 | 1.673303 | -0.517003 | 0.224849 | 1.387685 | 0.186466 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000172
|
BRD-K53123955-001-10-5
|
ACH-001128
|
MON_SOFT_TISSUE
|
HTS002
| 1 | 1.534844 | -5.699798 | 0.06376 | 1.428113 | 1.442079 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-001128
|
BRD-K53123955-001-10-5
|
ACH-000437
|
SW1088_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 2.314562 | -0.129248 | 0.041671 | 1.463664 | 0.000614 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000437
|
BRD-K53123955-001-10-5
|
ACH-000735
|
PECAPJ49_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 1.450446 | -0.081198 | -0.135663 | 1.296619 | 280.89178 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000735
|
BRD-K53123955-001-10-5
|
ACH-000643
|
HDQP1_BREAST
|
HTS002
| 1 | 1.326781 | -0.127673 | -0.064202 | 1.237687 | 213.231568 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000643
|
BRD-K53123955-001-10-5
|
ACH-000207
|
DETROIT562_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 2.005907 | -0.073668 | 0.041321 | 1.527242 | 0.29421 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000207
|
BRD-K53123955-001-10-5
|
ACH-000456
|
BCPAP_THYROID
|
HTS002
| 1 | 1.552737 | 0.257176 | -0.071235 | 1.385399 | 0.00207 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000456
|
BRD-K53123955-001-10-5
|
ACH-000260
|
SKNAS_AUTONOMIC_GANGLIA
|
HTS002
| 1 | 1.614799 | 0.028811 | -0.02534 | 1.330799 | 0.000389 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000260
|
BRD-K53123955-001-10-5
|
ACH-000019
|
MCF7_BREAST
|
HTS002
| 1 | 1.806984 | -0.834978 | 0.075582 | 1.305517 | 0.022894 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000019
|
BRD-K53123955-001-10-5
|
ACH-000582
|
COLO741_SKIN
|
HTS002
| 1 | 1.827144 | -0.128919 | 0.006777 | 1.326924 | 0.002596 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000582
|
BRD-K53123955-001-10-5
|
ACH-000990
|
HEC108_ENDOMETRIUM
|
HTS002
| 1 | 1.746869 | -0.212253 | -0.019008 | 1.415288 | 0.247284 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000990
|
BRD-K53123955-001-10-5
|
ACH-000592
|
TM31_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 1.650927 | 0.044061 | -0.035818 | 1.345601 | 0.004643 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000592
|
BRD-K53123955-001-10-5
|
ACH-000527
|
OVISE_OVARY
|
HTS002
| 1 | 1.75608 | -0.249195 | 0.025859 | 1.276177 | 0.006581 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000527
|
BRD-K53123955-001-10-5
|
ACH-000091
|
OV56_OVARY
|
HTS002
| 1 | 1.925414 | -0.368378 | 0.30231 | 1.248749 | 0.002752 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000091
|
BRD-K53123955-001-10-5
|
ACH-000759
|
MDAMB175VII_BREAST
|
HTS002
| 1 | 2.530543 | 0.475648 | -0.078381 | 1.115077 | 61.717978 | null |
niridazole
|
phosphofructokinase inhibitor
| null |
infectious disease
|
schistosomiasis
|
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
|
Launched
| true |
ACH-000759
|
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