broad_id
string
depmap_id
string
ccle_name
string
screen_id
string
upper_limit
int64
lower_limit
float64
slope
float64
r2
float64
auc
float64
ec50
float64
ic50
float64
name
string
moa
string
target
string
disease.area
string
indication
string
smiles
string
phase
string
passed_str_profiling
bool
row_name
string
BRD-K11640013-236-10-1
ACH-000791
RERFLCAD1_LUNG
HTS002
1
2.485495
-0.109882
0.176008
1.628032
0.004298
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000791
BRD-K11640013-236-10-1
ACH-000367
NCIH226_LUNG
HTS002
1
1.772841
-0.394182
0.175403
1.360846
0.050674
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000367
BRD-K11640013-236-10-1
ACH-001190
SKMEL2_SKIN
HTS002
1
2.0683
0.003855
-0.073796
1.43774
10,306,495,996,652,901,000,000,000,000,000,000,000,000
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-001190
BRD-K11640013-236-10-1
ACH-000244
DKMG_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.005448
-0.130885
0.083902
1.428036
0.007355
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000244
BRD-K11640013-236-10-1
ACH-000713
CAOV3_OVARY
HTS002
1
1.704969
-0.405419
0.238329
1.291292
0.025373
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000713
BRD-K11640013-236-10-1
ACH-000672
IALM_LUNG
HTS002
1
2.536702
-0.282264
0.1872
1.546499
0.00698
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000672
BRD-K11640013-236-10-1
ACH-000875
NCIH2347_LUNG
HTS002
1
3.284545
0.018072
-0.014244
1.459562
112,458,463,934,915,000,000,000,000,000,000
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000875
BRD-K11640013-236-10-1
ACH-000423
SKMEL3_SKIN
HTS002
1
1.539026
-0.132392
-0.014921
1.334238
3.577379
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000423
BRD-K11640013-236-10-1
ACH-000553
SQ1_LUNG
HTS002
1
1.583127
-0.033409
0.008907
1.350283
16,320.564047
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000553
BRD-K11640013-236-10-1
ACH-000834
UMUC1_URINARY_TRACT
HTS002
1
1.768868
-0.065418
-0.077626
1.352494
0.005996
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000834
BRD-K11640013-236-10-1
ACH-000252
LS1034_LARGE_INTESTINE
HTS002
1
2.300034
-0.380468
0.070909
1.48384
0.013783
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000252
BRD-K11640013-236-10-1
ACH-000329
CCFSTTG1_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.088251
-0.065571
-0.022396
1.512019
0.012696
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000329
BRD-K11640013-236-10-1
ACH-000669
SW900_LUNG
HTS002
1
1.72115
-0.402168
-0.018646
1.314975
0.034405
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000669
BRD-K11640013-236-10-1
ACH-000764
SH10TC_STOMACH
HTS002
1
1.657517
-0.14858
-0.086188
1.351102
0.203126
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000764
BRD-K11640013-236-10-1
ACH-000288
BT549_BREAST
HTS002
1
2.330991
0.026467
-0.017626
1.565861
7,079.948567
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000288
BRD-K11640013-236-10-1
ACH-000228
BICR31_UPPER_AERODIGESTIVE_TRACT
HTS002
1
2.131533
0.009276
-0.029338
1.54103
977.370434
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000228
BRD-K11640013-236-10-1
ACH-000977
LNCAPCLONEFGC_PROSTATE
HTS002
1
0.526382
-0.72343
-0.072771
0.91068
0.002493
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000977
BRD-K11640013-236-10-1
ACH-000397
TEN_ENDOMETRIUM
HTS002
1
2.339336
-0.054803
-0.062163
1.644467
0.019614
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000397
BRD-K11640013-236-10-1
ACH-000565
RCM1_LARGE_INTESTINE
HTS002
1
1.166093
-0.106996
-0.014614
1.144938
6,901,838.303
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000565
BRD-K11640013-236-10-1
ACH-000209
SNU1079_BILIARY_TRACT
HTS002
1
1.828702
-0.081601
-0.071638
1.381535
0.010889
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000209
BRD-K11640013-236-10-1
ACH-000927
BT474_BREAST
HTS002
1
1.515865
0.22957
-0.003009
1.208778
0.496295
null
sulfamethazine
PABA antagonist
null
gastroenterology
enteritis, enteritis
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1, Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Launched
true
ACH-000927
BRD-K53123955-001-10-5
ACH-000879
MFE296_ENDOMETRIUM
HTS002
1
2.707382
-0.014084
-0.003647
1.870691
1.322929
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000879
BRD-K53123955-001-10-5
ACH-000320
PSN1_PANCREAS
HTS002
1
1.744038
0.071396
-0.055168
1.426763
0.001179
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000320
BRD-K53123955-001-10-5
ACH-001145
OC316_OVARY
HTS002
1
2.24898
-0.41849
0.24352
1.368231
0.005199
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-001145
BRD-K53123955-001-10-5
ACH-000873
KYSE270_OESOPHAGUS
HTS002
1
1.508895
-0.0156
-0.02481
1.252389
0.027678
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000873
BRD-K53123955-001-10-5
ACH-000855
KYSE150_OESOPHAGUS
HTS002
1
2.02555
-0.10306
0.050079
1.436475
0.004012
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000855
BRD-K53123955-001-10-5
ACH-000913
ESS1_ENDOMETRIUM
HTS002
1
2.363238
-0.195478
0.114048
1.570141
0.012759
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000913
BRD-K53123955-001-10-5
ACH-000558
A172_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.574821
0.105086
-0.112184
1.699321
0.693897
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000558
BRD-K53123955-001-10-5
ACH-000593
BC3C_URINARY_TRACT
HTS002
1
1.870351
-0.324962
0.032906
1.475219
0.154306
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000593
BRD-K53123955-001-10-5
ACH-000488
TE11_OESOPHAGUS
HTS002
1
1.748652
-0.190095
0.333631
1.312666
0.012039
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000488
BRD-K53123955-001-10-5
ACH-000832
CAL27_UPPER_AERODIGESTIVE_TRACT
HTS002
1
2.210649
-0.023077
0.000251
1.553166
0.000043
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000832
BRD-K53123955-001-10-5
ACH-000781
NCIH2023_LUNG
HTS002
1
2.061427
-0.143665
0.049854
1.641572
1.679818
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000781
BRD-K53123955-001-10-5
ACH-000833
RH30_SOFT_TISSUE
HTS002
1
2.477592
-0.129669
0.013741
1.532508
0.000813
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000833
BRD-K53123955-001-10-5
ACH-000137
8MGBA_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.866521
-0.370116
0.529015
1.303173
0.009695
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000137
BRD-K53123955-001-10-5
ACH-000632
HS944T_SKIN
HTS002
1
2.480804
0.035248
0.034747
1.772074
0.006847
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000632
BRD-K53123955-001-10-5
ACH-000319
MPP89_PLEURA
HTS002
1
2.014639
-0.01168
0.004628
1.506747
0.064391
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000319
BRD-K53123955-001-10-5
ACH-000630
YD8_UPPER_AERODIGESTIVE_TRACT
HTS002
1
2.390916
-0.457916
0.190163
1.452113
0.008887
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000630
BRD-K53123955-001-10-5
ACH-000266
SNU213_PANCREAS
HTS002
1
2.431625
-0.090547
0.03832
1.574247
0.000871
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000266
BRD-K53123955-001-10-5
ACH-000047
GCIY_STOMACH
HTS002
1
1.660206
-0.239893
0.062325
1.240777
0.006025
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000047
BRD-K53123955-001-10-5
ACH-000273
SF539_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.55313
0.070194
-0.012957
1.318064
0.001009
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000273
BRD-K53123955-001-10-5
ACH-000682
SNU1066_UPPER_AERODIGESTIVE_TRACT
HTS002
1
0.774442
0.246971
0.024044
0.90035
0.224858
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000682
BRD-K53123955-001-10-5
ACH-000846
FADU_UPPER_AERODIGESTIVE_TRACT
HTS002
1
0.823901
0.350784
0.061627
0.882616
0.007011
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000846
BRD-K53123955-001-10-5
ACH-000804
NB1_AUTONOMIC_GANGLIA
HTS002
1
0.924692
1.036491
0.056449
0.97252
0.296656
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000804
BRD-K53123955-001-10-5
ACH-000609
SF126_CENTRAL_NERVOUS_SYSTEM
HTS002
1
0.735008
-0.007323
-0.044528
0.870048
0.000412
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000609
BRD-K53123955-001-10-5
ACH-000974
SNGM_ENDOMETRIUM
HTS002
1
2.423668
-0.395213
-0.023605
1.542899
0.016243
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000974
BRD-K53123955-001-10-5
ACH-000987
MEWO_SKIN
HTS002
1
1.457721
-0.174383
0.002297
1.190766
0.010164
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000987
BRD-K53123955-001-10-5
ACH-000787
LXF289_LUNG
HTS002
1
1.344528
0.002645
-0.027467
1.17227
0.07603
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000787
BRD-K53123955-001-10-5
ACH-000561
TT_OESOPHAGUS
HTS002
1
1.152161
0.021652
-0.15535
1.081481
0.000109
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000561
BRD-K53123955-001-10-5
ACH-000212
CAL120_BREAST
HTS002
1
2.021471
-0.316988
0.233437
1.316818
0.003991
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000212
BRD-K53123955-001-10-5
ACH-000753
JMSU1_URINARY_TRACT
HTS002
1
1.371387
-0.008593
-0.140623
1.263536
113,723,704,752,167,000,000,000,000,000,000,000,000,000,000
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000753
BRD-K53123955-001-10-5
ACH-000305
ECGI10_OESOPHAGUS
HTS002
1
1.903529
-0.10301
0.081344
1.342746
0.000595
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000305
BRD-K53123955-001-10-5
ACH-000250
KMRC20_KIDNEY
HTS002
1
1.100093
-0.069316
-0.02611
1.053944
0.758434
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000250
BRD-K53123955-001-10-5
ACH-000856
CAL51_BREAST
HTS002
1
2.064906
-0.212415
0.302782
1.539362
0.089221
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000856
BRD-K53123955-001-10-5
ACH-000046
ACHN_KIDNEY
HTS002
1
1.694481
-0.325615
0.113187
1.279767
0.018379
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000046
BRD-K53123955-001-10-5
ACH-000878
HCC15_LUNG
HTS002
1
1.555522
-0.550508
-0.037089
1.23791
0.035006
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000878
BRD-K53123955-001-10-5
ACH-000766
NCIH1648_LUNG
HTS002
1
1.265474
0.123361
-0.037297
1.165402
0.001181
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000766
BRD-K53123955-001-10-5
ACH-000666
NCIH1355_LUNG
HTS002
1
2.49382
0.053356
0.016953
1.657449
7.292999
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000666
BRD-K53123955-001-10-5
ACH-000014
HS294T_SKIN
HTS002
1
2.28851
-0.104537
0.086005
1.539908
0.003209
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000014
BRD-K53123955-001-10-5
ACH-000701
RMUGS_OVARY
HTS002
1
2.207268
-0.080481
0.010023
1.611982
0.110649
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000701
BRD-K53123955-001-10-5
ACH-000884
MDAMB435S_SKIN
HTS002
1
1.668921
-0.270952
0.189644
1.339216
0.088054
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000884
BRD-K53123955-001-10-5
ACH-000037
S117_SOFT_TISSUE
HTS002
1
2.103559
-0.231746
0.009435
1.641621
0.372801
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000037
BRD-K53123955-001-10-5
ACH-000504
SNB75_CENTRAL_NERVOUS_SYSTEM
HTS002
1
3.66152
-0.296109
-0.106941
1.692719
0.001344
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000504
BRD-K53123955-001-10-5
ACH-000502
TCCPAN2_PANCREAS
HTS002
1
2.07636
-0.495998
0.112163
1.202007
0.001378
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000502
BRD-K53123955-001-10-5
ACH-000886
NCIH2009_LUNG
HTS002
1
2.324391
-0.148774
0.134296
1.500506
0.00238
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000886
BRD-K53123955-001-10-5
ACH-000035
NCIH1650_LUNG
HTS002
1
1.462305
-0.052116
0.000799
1.226904
0.038444
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000035
BRD-K53123955-001-10-5
ACH-000661
WM1799_SKIN
HTS002
1
0.69353
2.235679
0.183833
0.90814
0.545862
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000661
BRD-K53123955-001-10-5
ACH-000843
HARA_LUNG
HTS002
1
2.784045
-0.157436
-0.006963
1.761572
0.010997
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000843
BRD-K53123955-001-10-5
ACH-000711
JIMT1_BREAST
HTS002
1
1.398846
-0.310877
-0.299486
1.267546
1.150726
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000711
BRD-K53123955-001-10-5
ACH-000232
U251MG_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.562903
-0.059959
0.154965
1.729226
0.008248
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000232
BRD-K53123955-001-10-5
ACH-000060
PANC1005_PANCREAS
HTS002
1
1.589999
0.10926
-0.120474
1.298396
0.062966
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000060
BRD-K53123955-001-10-5
ACH-000322
HT144_SKIN
HTS002
1
3.388119
-0.023418
-0.019176
2.15359
0.004304
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000322
BRD-K53123955-001-10-5
ACH-000736
SNU601_STOMACH
HTS002
1
1.509969
-0.139957
0.108348
1.302001
1.241639
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000736
BRD-K53123955-001-10-5
ACH-000809
KYSE410_OESOPHAGUS
HTS002
1
1.356682
-0.34253
-0.034607
1.183251
0.095058
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000809
BRD-K53123955-001-10-5
ACH-000747
NCIH1703_LUNG
HTS002
1
1.864474
-4.50504
0.760489
1.612622
0.591817
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000747
BRD-K53123955-001-10-5
ACH-000364
U2OS_BONE
HTS002
1
2.054799
0.198018
0.108153
1.574613
0.029465
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000364
BRD-K53123955-001-10-5
ACH-000679
OE19_OESOPHAGUS
HTS002
1
3.050024
-0.302931
0.05567
1.542105
0.001559
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000679
BRD-K53123955-001-10-5
ACH-000985
LS411N_LARGE_INTESTINE
HTS002
1
1.634154
-4.231559
0.504697
1.340365
0.111571
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000985
BRD-K53123955-001-10-5
ACH-000441
SH4_SKIN
HTS002
1
1.358168
0.101342
-0.14609
1.244862
0.000034
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000441
BRD-K53123955-001-10-5
ACH-000620
JHH1_LIVER
HTS002
1
1.866826
-0.079402
0.034254
1.438795
0.107227
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000620
BRD-K53123955-001-10-5
ACH-000853
NCIH661_LUNG
HTS002
1
1.858004
-0.54425
0.02496
1.507049
0.217718
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000853
BRD-K53123955-001-10-5
ACH-000102
GMS10_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.189415
-0.103964
0.202202
1.487228
0.002159
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000102
BRD-K53123955-001-10-5
null
null
HTS002
1
1.736157
-0.191851
0.051084
1.266114
0.003279
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
false
ACH-000925_FAILED_STR
BRD-K53123955-001-10-5
ACH-001239
WM2664_SKIN
HTS002
1
1.399898
-0.602242
0.0178
1.053617
0.000823
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-001239
BRD-K53123955-001-10-5
ACH-001321
TT_THYROID
HTS002
1
0.995466
0.859678
-0.954128
0.998259
0.250717
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-001321
BRD-K53123955-001-10-5
ACH-000279
EWS502_BONE
HTS002
1
2.435738
-0.167172
0.139387
1.479733
0.001019
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000279
BRD-K53123955-001-10-5
ACH-000172
TM87_SOFT_TISSUE
HTS002
1
1.673303
-0.517003
0.224849
1.387685
0.186466
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000172
BRD-K53123955-001-10-5
ACH-001128
MON_SOFT_TISSUE
HTS002
1
1.534844
-5.699798
0.06376
1.428113
1.442079
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-001128
BRD-K53123955-001-10-5
ACH-000437
SW1088_CENTRAL_NERVOUS_SYSTEM
HTS002
1
2.314562
-0.129248
0.041671
1.463664
0.000614
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000437
BRD-K53123955-001-10-5
ACH-000735
PECAPJ49_UPPER_AERODIGESTIVE_TRACT
HTS002
1
1.450446
-0.081198
-0.135663
1.296619
280.89178
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000735
BRD-K53123955-001-10-5
ACH-000643
HDQP1_BREAST
HTS002
1
1.326781
-0.127673
-0.064202
1.237687
213.231568
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000643
BRD-K53123955-001-10-5
ACH-000207
DETROIT562_UPPER_AERODIGESTIVE_TRACT
HTS002
1
2.005907
-0.073668
0.041321
1.527242
0.29421
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000207
BRD-K53123955-001-10-5
ACH-000456
BCPAP_THYROID
HTS002
1
1.552737
0.257176
-0.071235
1.385399
0.00207
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000456
BRD-K53123955-001-10-5
ACH-000260
SKNAS_AUTONOMIC_GANGLIA
HTS002
1
1.614799
0.028811
-0.02534
1.330799
0.000389
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000260
BRD-K53123955-001-10-5
ACH-000019
MCF7_BREAST
HTS002
1
1.806984
-0.834978
0.075582
1.305517
0.022894
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000019
BRD-K53123955-001-10-5
ACH-000582
COLO741_SKIN
HTS002
1
1.827144
-0.128919
0.006777
1.326924
0.002596
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000582
BRD-K53123955-001-10-5
ACH-000990
HEC108_ENDOMETRIUM
HTS002
1
1.746869
-0.212253
-0.019008
1.415288
0.247284
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000990
BRD-K53123955-001-10-5
ACH-000592
TM31_CENTRAL_NERVOUS_SYSTEM
HTS002
1
1.650927
0.044061
-0.035818
1.345601
0.004643
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000592
BRD-K53123955-001-10-5
ACH-000527
OVISE_OVARY
HTS002
1
1.75608
-0.249195
0.025859
1.276177
0.006581
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000527
BRD-K53123955-001-10-5
ACH-000091
OV56_OVARY
HTS002
1
1.925414
-0.368378
0.30231
1.248749
0.002752
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000091
BRD-K53123955-001-10-5
ACH-000759
MDAMB175VII_BREAST
HTS002
1
2.530543
0.475648
-0.078381
1.115077
61.717978
null
niridazole
phosphofructokinase inhibitor
null
infectious disease
schistosomiasis
[O-][N+](=O)c1cnc(s1)N1CCNC1=O
Launched
true
ACH-000759