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ZIP9 is a Druggable Determinant of Sex Differences in Melanoma
|
cancer biology
|
Powerful detection of polygenic selection and evidence of environmental adaptation in US beef cattle
|
genomics
|
Synchronised oscillations in growing cell populations are explained by demographic noise
|
cell biology
|
Architecture and assembly dynamics of the essential mitochondrial TIM chaperone systems
|
biophysics
|
Human and macaque pairs employ different coordination strategies in a dyadic decision game with face-to-face action visibility
|
neuroscience
|
Dynamic changes in tRNA modifications and abundance during T-cell activation
|
genomics
|
Cropping systems impact changes in soil fungal, but not prokaryote, alpha-diversity and community composition stability over a growing season in a long-term field trial.
|
microbiology
|
Hippocampal-medial prefrontal event segmentation and integration contribute to episodic memory formation
|
neuroscience
|
Evolutionary Pressures and Codon Bias in Low Complexity Regions of Plasmodia Parasites
|
bioinformatics
|
From work stress to disease: A computational model
|
physiology
|
Morphognostic honey bees communicating nectar location through dance movements
|
animal behavior and cognition
|
Functional Organization of the Maternal and Paternal Human 4D Nucleome
|
genomics
|
V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding affinity
|
microbiology
|
pyComBat, a Python tool for batch effects correction in high-throughput molecular data using empirical Bayes methods
|
bioinformatics
|
Target deconvolution using in vitro evolution in haploid human cells
|
genomics
|
Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrains
|
genomics
|
Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network
|
genetics
|
Anaerobic sulfur oxidation underlies adaptation of a chemosynthetic symbiont to oxic-anoxic interfaces
|
microbiology
|
Brain network motifs are markers of loss and recovery of consciousness
|
neuroscience
|
Cortical Depth-Dependent Modeling of Visual Hemodynamic Responses
|
neuroscience
|
Causal evidence for a cerebellar role in prefrontal-hippocampal interaction in spatial working memory decision-making
|
neuroscience
|
Temporal context actively shapes EEG signatures of time perception
|
neuroscience
|
Plasmid analysis of NDM metallo-β-lactamase-producing Enterobacterales isolated in Vietnam
|
microbiology
|
Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum
|
developmental biology
|
Different temporal trends in vascular plant and bryophytes communities along elevational gradients over four decades of warming
|
ecology
|
The p53-p21 axis plays a central role in lymphatic homeostasis and disease
|
developmental biology
|
Clinal and seasonal change are correlated in Drosophila melanogaster natural populations
|
evolutionary biology
|
Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila melanogaster
|
evolutionary biology
|
The histone variant H2A.W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation
|
genomics
|
Reward learning and working memory: effects of massed versus spaced training and post-learning delay period
|
neuroscience
|
celldeath: a tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition
|
cell biology
|
Genetic analyses identify widespread sex-differential participation bias
|
genetics
|
The glycolysis regulator PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma.
|
cell biology
|
A piRNA-lncRNA regulatory network initiates responder and trailer piRNA formation during mosquito embryonic development
|
molecular biology
|
Kappa but not delta or mu opioid receptors form homodimers at low membrane densities
|
biochemistry
|
Flagellar dynamics reveal fluctuations and kinetic limit in the Escherichia coli chemotaxis network
|
biophysics
|
T606-phosphorylation deprives the function of Kaiso as a transcription repressor
|
molecular biology
|
Revisiting giraffe photo-identification using deep learning and network analysis
|
ecology
|
HumGut: A comprehensive Human Gut prokaryotic genomes collection filtered by metagenome data
|
microbiology
|
Sponging of glutamate at the outer plasma membrane surface reveals roles for glutamate in development
|
plant biology
|
MeSSII interplays the amylose and amylopectin biosynthesis by protein interactions in cassava storage root
|
plant biology
|
The cytosolic Arabidopsis thaliana cysteine desulfurase ABA3 delivers sulfur to the sulfurtransferase STR18
|
plant biology
|
Age-dependent selection on MHC class 2 variation in a free-living ruminant
|
evolutionary biology
|
Non-Parametric Analysis of Inter-Individual Relations Using an Attention-Based Neural Network
|
animal behavior and cognition
|
CD19-targeting CAR T cells potently redirected to kill solid tumor cells
|
cancer biology
|
A natural timeless polymorphism allowing circadian clock synchronization in 'white nights'
|
neuroscience
|
Hierarchical progressive learning of cell identities in single-cell data
|
bioinformatics
|
DAISM-DNNXMBD: Highly accurate cell type proportion estimation with in silico data augmentation and deep neural networks
|
bioinformatics
|
Tracking bacterial lineages in complex and dynamic environments with applications to growth control and persistence
|
microbiology
|
A novel platform of RNA 2-O-methylation high-throughput and site-specific quantification tools revealed its broad distribution
|
biochemistry
|
Evaluating the transcriptional fidelity of cancer models
|
cancer biology
|
Flexible multivariate linear mixed models for structured multiple traits
|
genetics
|
Frisky CALF sometimes outruns LASSO
|
bioinformatics
|
The Hoja loca1 Mutant and AUX/IAA Function in Phytomer Development
|
plant biology
|
DeepLC can predict retention times for peptides that carry as-yet unseen modifications
|
bioinformatics
|
Evaluating and integrating spatial capture-recapture models with data of variable individual identifiability
|
ecology
|
Homeostatic control of synaptic rewiring in recurrent networks induces the formation of stable memory engrams
|
neuroscience
|
Reconstruction of microbial haplotypes by integration of statistical and physical linkage in scaffolding
|
bioinformatics
|
Multimodal brain imaging study of 36,678 participants reveals adverse effects of moderate drinking
|
neuroscience
|
Distinct ensembles in the noradrenergic locus coeruleus evoke diverse cortical states
|
neuroscience
|
Highly Versatile, Non-Invasive Method for Collecting Buccal DNA from Free-Ranging Non-Human Primates
|
genetics
|
Dopamine Signaling in the Dorsomedial Striatum Promotes Compulsive Behavior
|
neuroscience
|
Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments
|
cancer biology
|
Premalignant Nf1,Trp53-null Oligodendrocyte Precursor Cells BecomeStalled in a Heterogeneous State of Replication Stress BeforeGliomagenesis
|
cancer biology
|
Phylogenetic, geographic and ecological distribution of a green-brown polymorphisms in European Orthopterans
|
evolutionary biology
|
A Mendelian randomization study of glycemic and anthropometric traits and Parkinson's disease
|
genetics
|
Highly efficient multiplex editing: One-shot generation of 8x Nicotiana benthamiana and 12x Arabidopsis mutants
|
plant biology
|
The quorum-sensing systems of Vibrio campbellii DS40M4 and BB120 are genetically and functionally distinct
|
microbiology
|
Persister state-directed transitioning and vulnerability in melanoma
|
cancer biology
|
Mapping shifts in nanopore signal to changes in protein and protein-DNA conformation
|
biophysics
|
Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer
|
cancer biology
|
Cell-type specialization in the brain is encoded by specific long-range chromatin topologies
|
molecular biology
|
Perceptual decisions and oculomotor responses rely on temporally distinct streams of evidence
|
neuroscience
|
Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodelling
|
neuroscience
|
Exploring the understudied human kinome for research and therapeutic opportunities
|
systems biology
|
Pro-metastatic gene expression, immune evasion and an altered HPV spectrum characterize an aggressive subtype of cervical cancer
|
cancer biology
|
Admixture has obscured signals of historical hard sweeps in humans
|
genomics
|
Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs
|
genomics
|
STEP inhibition prevents Aβ mediated damage in dendritic complexity and spine density in Alzheimer's disease.
|
neuroscience
|
Chromatin dynamics during hematopoiesis reveal discrete regulatory modules instructing differentiation
|
developmental biology
|
Size-dependent eco-evolutionary feedbacks in fisheries
|
ecology
|
Distributed coding of stimulus magnitude in rodent prefrontal cortex
|
neuroscience
|
Low-frequency neural tracking of speech envelope reflects the convolution of evoked responses to acoustic edges, not oscillatory entrainment
|
neuroscience
|
The Neuroanatomy of Speech Processing: A Large-Scale Lesion Study
|
neuroscience
|
Evaluating features of scientific conferences: A call for improvements
|
scientific communication and education
|
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
|
cell biology
|
Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene
|
molecular biology
|
The role of KMT2D and KDM6A in cardiac development: A cross-species analysis in humans, mice, and zebrafish
|
developmental biology
|
A single-cell gene regulatory network inference method for identifying complex regulatory dynamics across cell phenotypes.
|
bioinformatics
|
Sleep spindles preferentially consolidate weakly encoded memories
|
neuroscience
|
FlexDotPlot: a universal and modular dot plot visualization tool for complex multifaceted data
|
bioinformatics
|
A Whole-Brain Map and Assay Parameter Analysis of Mouse VTA Dopaminergic Activation
|
neuroscience
|
Genomic Epidemiology with Mixed Samples
|
bioinformatics
|
Mice carrying paternal knockout of imprinted Grb10 do not show compulsive behaviours
|
animal behavior and cognition
|
The lateral entorhinal cortex is a hub for local and global dysfunction in pre-tauopathy states
|
neuroscience
|
Genetic architecture of a mutation's expressivity
|
genetics
|
Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression
|
physiology
|
Multi-fluorescence high-resolution episcopic microscopy (MF-HREM) for three dimensional imaging of adult murine organs
|
biophysics
|
Achieving high-quality ddRAD-like reference catalogs for non-model species: the power of overlapping paired-end reads.
|
evolutionary biology
|
Structural and functional networks involved in empathy for positive and negative emotions in late adulthood
|
neuroscience
|
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