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Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells
immunology
CDK1 controls CHMP7-dependent nuclear envelope reformation
cell biology
Sequence determinants and evolution of constitutive and alternative splicing in yeast species
systems biology
Imprints of tumor mutation burden on chromosomes and relation to cancer risk in humans: A pan-cancer analysis
cancer biology
Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana
evolutionary biology
SARS-CoV-2 Encodes a PPxY Late Domain Motif Known to Enhance Budding and Spread in Enveloped RNA Viruses
bioinformatics
GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background
genetics
Human iPSC-derived cerebral organoids model features of Leigh Syndrome and reveal abnormal corticogenesis
cell biology
Negative feedback may suppress variation to improve collective foraging performance
ecology
A quantitative measure of functional redundancy in microbial ecosystems
microbiology
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation
microbiology
Electrical Oscillations of Isolated Brain Microtubules
biophysics
A Substantia Innominata-midbrain Circuit Controls a General Aggressive Response
neuroscience
Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens.
biochemistry
Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2
microbiology
SwabExpress: An end-to-end protocol for extraction-free COVID-19 testing
molecular biology
Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion
molecular biology
Mask, the Drosophila Ankyrin Repeat and KH domain-containing protein, regulates microtubule dynamics
neuroscience
Tumor secreted extracellular vesicles regulate T-cell costimulation and can be manipulated to induce tumor-specific T-cell responses
cancer biology
Developmental system drift in one tooth facilitates the adaptation of the other tooth
evolutionary biology
Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex
neuroscience
Effector membrane translocation biosensors reveal G protein and β-arrestin coupling profiles of 100 therapeutically relevant GPCRs
pharmacology and toxicology
Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect after a Drug Repurposing Screen
microbiology
Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome
cell biology
MaxHiC: robust estimation of chromatin interaction frequency in Hi-C and capture Hi-C experiments
bioinformatics
Physiology and function of PNS axons rely on glycolic metabolism in myelinating Schwann cells
neuroscience
Proliferation impairs cell viability via energy depletion
physiology
Degradation of Alzheimers Amyloid-beta by a Catalytically Inactive Insulin Degrading Enzyme
biophysics
Synchronizing vigilance or taking turns as sentinels? The importance of testing coordination
animal behavior and cognition
Biochemical, structural insights of newly isolated AA16 family of Lytic Polysaccharide Monooxygenase (LPMO) from Aspergillus fumigatus and investigation of its synergistic effect using biomass.
biochemistry
Coupling spectral and resource-use complementarity in experimental grassland and forest communities
ecology
Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
neuroscience
Functional Annotation of Human Cognitive States using Deep Graph Convolution
neuroscience
Efficient Representations of Tumor Diversity with Paired DNA-RNA Aberrations
genomics
Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan
genetics
Conformational Tuning of Amylin by Charged Styrene-maleic-acid Copolymers
biophysics
Spatial distribution of rice lectin protein r40g3 determines its dual regulatory role in imparting salinity tolerance while impeding seed development
plant biology
State-selective Modulation of Heterotrimeric Gαs Signaling with Macrocyclic Peptides
biochemistry
Flow-cell based technology for massively parallelcharacterization of base-modified DNA aptamers
bioengineering
Reverse plasticity underlies rapid evolution by clonal selection within populations of fibroblastspropagated on a novel soft substrate
evolutionary biology
Cooperative stator assembly of bacterial flagellar motor mediated by rotation
biophysics
Flap dynamics in pepsin-like aspartic proteases: a computational perspective using Plasmepsin-II and BACE-1 as model systems
biophysics
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage
cancer biology
Understanding the effects of contact structures and information sharing on the FMD transmission among beef cattle farms
microbiology
Tinamou egg color displacement at ecoregion co-partitioning
evolutionary biology
Intraflagellar transport-A deficiency attenuates ADPKD in a renal tubular- and maturation-dependent manner
genetics
The Genetic Basis of phage susceptibility, cross-resistance and host-range in Salmonella
microbiology
Flood-induced interspecific interactions in spring-fed tributary as an ecosystem function of heterogeneous river networks
ecology
LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion
cell biology
Bayesian inference of kinetic schemes for ion channels by Kalman filtering
bioinformatics
Subcortical Circuits Mediate Communication Between Primary Sensory Cortical Areas
neuroscience
Single-cell resolution analysis of the crosstalk between chemogenically activated astrocytes and microglia
neuroscience
A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior
neuroscience
Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson's disease
neuroscience
A validation scale to determine the readiness of environmental DNA assays for routine species monitoring
molecular biology
On a Reef Far, Far Away: Anthropogenic Impacts Following Extreme Storms Affect Sponge Health and Bacterial Communities
microbiology
Titration of in-cellula affinities of protein-protein interactions
biochemistry
Random peptides rich in small and disorder-promoting amino acids are less likely to be harmful
evolutionary biology
Plant pathogen infection risk tracks global crop yields under climate change
ecology
Evolutionary analysis of the LORELEI gene family in angiosperms reveals regulatory subfunctionalization
plant biology
Evolutionary Genetic Species Detected in Prokaryotes by Applying the K/θ Ratio to DNA Sequences
evolutionary biology
Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell Transplantation
genomics
DNA damage independent inhibition of NF-κB transcription by anthracyclines
immunology
Geometric model incorporating prey's turn and predator attack endpoint explains multiple preferred escape trajectories
animal behavior and cognition
The impact of purifying and background selection on the inference of population history: problems and prospects
evolutionary biology
Parental population range expansion before secondary contact promotes heterosis
evolutionary biology
Relative salience signaling within a thalamo-orbitofrontal circuit governs learning rate
neuroscience
On the fitness of informative cues in complex environments
evolutionary biology
Baseline Resting-State Functional Connectivity Determines Subsequent Pain Ratings to a Tonic Ecologically Valid Experimental Model of Orofacial Pain
neuroscience
Super-selective reconstruction of causal and direct connectivity with application to in-vitro iPSC neuronal networks
neuroscience
Connectomes across development reveal principles of brain maturation
neuroscience
Nano-analytical Characterization of Breast Tissue Biopsies Reveals an Association between Spherical Nano and Micro Particles and Invasive Malignant Breast Tumours.
cancer biology
Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease
biophysics
New Music System Reveals Spectral Contribution to Statistical Learning
neuroscience
The habenula clock influences prediction of danger
neuroscience
Single-cell analysis reveals mechanisms of plasticity of leukemia initiating cells
cancer biology
Hugin+ neurons link the sleep homeostat to circadian clock neurons
neuroscience
Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays
genomics
A Behavioral Association Between Prediction Errors and Risk-Seeking: Theory and Evidence
neuroscience
α-Synuclein facilitates clathrin assembly in synaptic vesicle endocytosis
neuroscience
Removing the Gβγ-SNAP25 brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
physiology
Suicidal thoughts, behaviors, and event-related potentials: A systematic review and meta-analysis
neuroscience
OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches
bioinformatics
Characterizing the body morphology of the first metacarpal in the Homininae using 3D geometric morphometrics
paleontology
Specificity of Gβ and γ subunits to the SNARE complex both at rest and after α2aadrenergic receptor stimulation
biochemistry
Personality, Subjective Well-Being, and the Serotonin 1a Receptor Gene in Common Marmosets (Callithrix jacchus)
animal behavior and cognition
Downregulation of Perilipin1 by IMD leads to LD reconfiguration and adaptation to bacterial infection in Drosophila
immunology
A novel DNA binding mode, conformational change and intramolecular signaling in MutS upon mismatch recognition in replication DNA structures
biochemistry
Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
developmental biology
Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
neuroscience
Representative diatom and coccolithophore species exhibit divergent responses throughout simulated upwelling cycles
ecology
Reproductive biology of wild and domesticated Ensete ventricosum: Further evidence for maintenance of sexual reproductive capacity in a vegetatively propagated perennial crop
ecology
Trait-based responses to forestry and reindeer husbandry modify long-term changes in forest understories
ecology
Auditory cue combination in perceptual externalization of static sound sources: a model-based meta analysis
neuroscience
Detecting neural state transitions underlying event segmentation
neuroscience
Child specific activation in left auditory cortex predicts behavioral performance in inhibition tasks.
neuroscience
tRNA Biogenesis and Specific Aminoacyl-tRNA Synthetases Regulate Senescence Stability Under the Control of mTOR
cancer biology
Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana
plant biology
Infanticide by females is a leading source of juvenile mortality in a large social carnivore
animal behavior and cognition
Steric blockage of lysenin toxin by crowding
biophysics