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Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells
|
immunology
|
CDK1 controls CHMP7-dependent nuclear envelope reformation
|
cell biology
|
Sequence determinants and evolution of constitutive and alternative splicing in yeast species
|
systems biology
|
Imprints of tumor mutation burden on chromosomes and relation to cancer risk in humans: A pan-cancer analysis
|
cancer biology
|
Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana
|
evolutionary biology
|
SARS-CoV-2 Encodes a PPxY Late Domain Motif Known to Enhance Budding and Spread in Enveloped RNA Viruses
|
bioinformatics
|
GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background
|
genetics
|
Human iPSC-derived cerebral organoids model features of Leigh Syndrome and reveal abnormal corticogenesis
|
cell biology
|
Negative feedback may suppress variation to improve collective foraging performance
|
ecology
|
A quantitative measure of functional redundancy in microbial ecosystems
|
microbiology
|
Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation
|
microbiology
|
Electrical Oscillations of Isolated Brain Microtubules
|
biophysics
|
A Substantia Innominata-midbrain Circuit Controls a General Aggressive Response
|
neuroscience
|
Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens.
|
biochemistry
|
Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2
|
microbiology
|
SwabExpress: An end-to-end protocol for extraction-free COVID-19 testing
|
molecular biology
|
Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion
|
molecular biology
|
Mask, the Drosophila Ankyrin Repeat and KH domain-containing protein, regulates microtubule dynamics
|
neuroscience
|
Tumor secreted extracellular vesicles regulate T-cell costimulation and can be manipulated to induce tumor-specific T-cell responses
|
cancer biology
|
Developmental system drift in one tooth facilitates the adaptation of the other tooth
|
evolutionary biology
|
Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex
|
neuroscience
|
Effector membrane translocation biosensors reveal G protein and β-arrestin coupling profiles of 100 therapeutically relevant GPCRs
|
pharmacology and toxicology
|
Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect after a Drug Repurposing Screen
|
microbiology
|
Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome
|
cell biology
|
MaxHiC: robust estimation of chromatin interaction frequency in Hi-C and capture Hi-C experiments
|
bioinformatics
|
Physiology and function of PNS axons rely on glycolic metabolism in myelinating Schwann cells
|
neuroscience
|
Proliferation impairs cell viability via energy depletion
|
physiology
|
Degradation of Alzheimers Amyloid-beta by a Catalytically Inactive Insulin Degrading Enzyme
|
biophysics
|
Synchronizing vigilance or taking turns as sentinels? The importance of testing coordination
|
animal behavior and cognition
|
Biochemical, structural insights of newly isolated AA16 family of Lytic Polysaccharide Monooxygenase (LPMO) from Aspergillus fumigatus and investigation of its synergistic effect using biomass.
|
biochemistry
|
Coupling spectral and resource-use complementarity in experimental grassland and forest communities
|
ecology
|
Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
|
neuroscience
|
Functional Annotation of Human Cognitive States using Deep Graph Convolution
|
neuroscience
|
Efficient Representations of Tumor Diversity with Paired DNA-RNA Aberrations
|
genomics
|
Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan
|
genetics
|
Conformational Tuning of Amylin by Charged Styrene-maleic-acid Copolymers
|
biophysics
|
Spatial distribution of rice lectin protein r40g3 determines its dual regulatory role in imparting salinity tolerance while impeding seed development
|
plant biology
|
State-selective Modulation of Heterotrimeric Gαs Signaling with Macrocyclic Peptides
|
biochemistry
|
Flow-cell based technology for massively parallelcharacterization of base-modified DNA aptamers
|
bioengineering
|
Reverse plasticity underlies rapid evolution by clonal selection within populations of fibroblastspropagated on a novel soft substrate
|
evolutionary biology
|
Cooperative stator assembly of bacterial flagellar motor mediated by rotation
|
biophysics
|
Flap dynamics in pepsin-like aspartic proteases: a computational perspective using Plasmepsin-II and BACE-1 as model systems
|
biophysics
|
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage
|
cancer biology
|
Understanding the effects of contact structures and information sharing on the FMD transmission among beef cattle farms
|
microbiology
|
Tinamou egg color displacement at ecoregion co-partitioning
|
evolutionary biology
|
Intraflagellar transport-A deficiency attenuates ADPKD in a renal tubular- and maturation-dependent manner
|
genetics
|
The Genetic Basis of phage susceptibility, cross-resistance and host-range in Salmonella
|
microbiology
|
Flood-induced interspecific interactions in spring-fed tributary as an ecosystem function of heterogeneous river networks
|
ecology
|
LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion
|
cell biology
|
Bayesian inference of kinetic schemes for ion channels by Kalman filtering
|
bioinformatics
|
Subcortical Circuits Mediate Communication Between Primary Sensory Cortical Areas
|
neuroscience
|
Single-cell resolution analysis of the crosstalk between chemogenically activated astrocytes and microglia
|
neuroscience
|
A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior
|
neuroscience
|
Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson's disease
|
neuroscience
|
A validation scale to determine the readiness of environmental DNA assays for routine species monitoring
|
molecular biology
|
On a Reef Far, Far Away: Anthropogenic Impacts Following Extreme Storms Affect Sponge Health and Bacterial Communities
|
microbiology
|
Titration of in-cellula affinities of protein-protein interactions
|
biochemistry
|
Random peptides rich in small and disorder-promoting amino acids are less likely to be harmful
|
evolutionary biology
|
Plant pathogen infection risk tracks global crop yields under climate change
|
ecology
|
Evolutionary analysis of the LORELEI gene family in angiosperms reveals regulatory subfunctionalization
|
plant biology
|
Evolutionary Genetic Species Detected in Prokaryotes by Applying the K/θ Ratio to DNA Sequences
|
evolutionary biology
|
Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell Transplantation
|
genomics
|
DNA damage independent inhibition of NF-κB transcription by anthracyclines
|
immunology
|
Geometric model incorporating prey's turn and predator attack endpoint explains multiple preferred escape trajectories
|
animal behavior and cognition
|
The impact of purifying and background selection on the inference of population history: problems and prospects
|
evolutionary biology
|
Parental population range expansion before secondary contact promotes heterosis
|
evolutionary biology
|
Relative salience signaling within a thalamo-orbitofrontal circuit governs learning rate
|
neuroscience
|
On the fitness of informative cues in complex environments
|
evolutionary biology
|
Baseline Resting-State Functional Connectivity Determines Subsequent Pain Ratings to a Tonic Ecologically Valid Experimental Model of Orofacial Pain
|
neuroscience
|
Super-selective reconstruction of causal and direct connectivity with application to in-vitro iPSC neuronal networks
|
neuroscience
|
Connectomes across development reveal principles of brain maturation
|
neuroscience
|
Nano-analytical Characterization of Breast Tissue Biopsies Reveals an Association between Spherical Nano and Micro Particles and Invasive Malignant Breast Tumours.
|
cancer biology
|
Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease
|
biophysics
|
New Music System Reveals Spectral Contribution to Statistical Learning
|
neuroscience
|
The habenula clock influences prediction of danger
|
neuroscience
|
Single-cell analysis reveals mechanisms of plasticity of leukemia initiating cells
|
cancer biology
|
Hugin+ neurons link the sleep homeostat to circadian clock neurons
|
neuroscience
|
Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays
|
genomics
|
A Behavioral Association Between Prediction Errors and Risk-Seeking: Theory and Evidence
|
neuroscience
|
α-Synuclein facilitates clathrin assembly in synaptic vesicle endocytosis
|
neuroscience
|
Removing the Gβγ-SNAP25 brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
|
physiology
|
Suicidal thoughts, behaviors, and event-related potentials: A systematic review and meta-analysis
|
neuroscience
|
OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches
|
bioinformatics
|
Characterizing the body morphology of the first metacarpal in the Homininae using 3D geometric morphometrics
|
paleontology
|
Specificity of Gβ and γ subunits to the SNARE complex both at rest and after α2aadrenergic receptor stimulation
|
biochemistry
|
Personality, Subjective Well-Being, and the Serotonin 1a Receptor Gene in Common Marmosets (Callithrix jacchus)
|
animal behavior and cognition
|
Downregulation of Perilipin1 by IMD leads to LD reconfiguration and adaptation to bacterial infection in Drosophila
|
immunology
|
A novel DNA binding mode, conformational change and intramolecular signaling in MutS upon mismatch recognition in replication DNA structures
|
biochemistry
|
Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
|
developmental biology
|
Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
|
neuroscience
|
Representative diatom and coccolithophore species exhibit divergent responses throughout simulated upwelling cycles
|
ecology
|
Reproductive biology of wild and domesticated Ensete ventricosum: Further evidence for maintenance of sexual reproductive capacity in a vegetatively propagated perennial crop
|
ecology
|
Trait-based responses to forestry and reindeer husbandry modify long-term changes in forest understories
|
ecology
|
Auditory cue combination in perceptual externalization of static sound sources: a model-based meta analysis
|
neuroscience
|
Detecting neural state transitions underlying event segmentation
|
neuroscience
|
Child specific activation in left auditory cortex predicts behavioral performance in inhibition tasks.
|
neuroscience
|
tRNA Biogenesis and Specific Aminoacyl-tRNA Synthetases Regulate Senescence Stability Under the Control of mTOR
|
cancer biology
|
Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana
|
plant biology
|
Infanticide by females is a leading source of juvenile mortality in a large social carnivore
|
animal behavior and cognition
|
Steric blockage of lysenin toxin by crowding
|
biophysics
|
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