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Transcriptomic analysis of human and mouse muscle during hyperinsulinemia demonstrates insulin receptor downregulation as a mechanism for insulin resistance
|
physiology
|
Endocytosis against high turgor pressure is made easier by partial protein coating and a freely rotating base
|
biophysics
|
Negative Affect Induces Rapid Learning of Counterfactual Representations: A Model-based Facial Expression Analysis Approach
|
neuroscience
|
Coding Triplets in the Transfer RNA acceptor Arm and Their Role in Present and Past tRNA Recognition
|
genetics
|
Internal noise measures in coarse and fine motion direction discrimination tasks, and the correlation with autism traits
|
neuroscience
|
Polymer brush bilayers under stationary shear motion at linear response regime: A theoretical approach
|
biophysics
|
What the odor is not: Estimation by elimination
|
neuroscience
|
The Cdc14 phosphatase controls resolution of recombination intermediates and crossover formation during meiosis
|
genetics
|
The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA regulation
|
molecular biology
|
Conserving unprotected important coastal habitats in the Yellow Sea: shorebird occurrence, distribution and food resources at Lianyungang
|
ecology
|
Eco-evolutionary dynamics further weakens mutualistic interaction and coexistence under population decline
|
ecology
|
Event segmentation reveals working memory forgetting rate
|
neuroscience
|
Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa
|
molecular biology
|
Publicly available transcriptomes provide the opportunity for dual RNA-Seq meta analysis in Plasmodium infection
|
bioinformatics
|
Common variants associated with OSMR expression contribute to carotid plaque vulnerability, but not to cardiovascular disease in humans
|
genetics
|
Liver X Receptor; Controls Hepatic Stellate Cell Activation via Hedgehog Signaling
|
cell biology
|
Balancing selection of the Intracellular Pathogen Response in natural Caenorhabditis elegans populations
|
genetics
|
A candidate causal variant underlying both enhanced cognitive performance and increased risk of bipolar disorder
|
genetics
|
PME-1 suppresses anoikis, and is associated with therapy relapse of PTEN-deficient prostate cancers
|
cancer biology
|
A stable pollination environment limits current but not potential evolution of floral traits
|
evolutionary biology
|
Protein structure without structure determination: direct coupling analysis based on in vitro evolution
|
evolutionary biology
|
Variations in Structural MRI Quality Significantly Impact Commonly-Used Measures of Brain Anatomy
|
neuroscience
|
Rapid neural representations of personally relevant faces
|
neuroscience
|
Single trial dynamics of attentional intensity in visual area V4
|
neuroscience
|
Quantifying Climatic and Socio-Economic Influences on Urban Malaria in Surat, India: A Modelling Study
|
ecology
|
Genomic data and multi-species demographic modelling uncover past hybridization between currently allopatric freshwater species
|
evolutionary biology
|
Effective clustering for single cell sequencing cancer data
|
cancer biology
|
Global mammalian zooregions reveal a signal of past human impacts
|
ecology
|
Recovery of trait heritability from whole genome sequence data
|
genetics
|
The PIWI/piRNA response is relaxed in a rodent that lacks mobilizing transposable elements
|
evolutionary biology
|
Mammalian mitochondrial mutational spectrum as a hallmark of cellular and organismal aging.
|
genomics
|
Familiar neighbours, but not relatives, enhance fitness in a territorial mammal
|
evolutionary biology
|
The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells
|
microbiology
|
Library Preparation and Sequencing Platform Introduce Bias in Metagenomic-Based Characterizations of Microbiomes
|
microbiology
|
Phylogenetic inference of changes in amino acid propensities with single-position resolution
|
evolutionary biology
|
Extensive genetic mixing within the clam genus Corbicula
|
evolutionary biology
|
Rate-limiting transport of positive charges through the Sec-machinery is integral to the mechanism of protein transport
|
biochemistry
|
Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons
|
genomics
|
Population receptive fields of human primary visual cortex organised as DC-balanced bandpass filters.
|
neuroscience
|
CRISPR-SID: identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
|
cancer biology
|
OpenAnnotate: a web server to annotate the chromatin accessibility of genomic regions
|
bioinformatics
|
Rapid label-free identification of pathogenic bacteria species from a minute quantity 1 exploiting three-dimensional quantitative phase imaging and artificial neural network
|
microbiology
|
Quality control of large genome datasets using genome fingerprints
|
genomics
|
Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer
|
immunology
|
Heterologous Cas9 and non-homologous end joining as a Potentially Organism-Agnostic Knockout (POAK) system in bacteria
|
synthetic biology
|
Heterochromatin renewal after release from growth arrest controls genome-wide transcription re-activation in S.cerevisiae
|
molecular biology
|
MetaNovo: a probabilistic approach to peptide discovery in complex mass spectrometry datasets
|
bioinformatics
|
An Integrated Platform for High-Throughput Nanoscopy
|
biophysics
|
Inter-subunit coupling enables fast CO2-fixation by reductive carboxylases
|
biophysics
|
Network science inspires novel tree shape statistics
|
bioinformatics
|
A suite of rare microbes interacts with a dominant, heritable, fungal endophyte to influence plant trait expression
|
ecology
|
Stabilising effects of competition and diversity determine vaccine impact on antibiotic resistance evolution
|
evolutionary biology
|
Reward motivation increases univariate activity but has limited effect on coding of task-relevant information across the frontoparietal cortex
|
neuroscience
|
Reference plasmid pHXB2_D is an HIV-1 molecular clone that exhibits identical LTRs and a single integration site indicative of an HIV provirus
|
genomics
|
Coupling Metastasis to pH-Sensing GPR68 Using a Novel Small Molecule Inhibitor
|
cancer biology
|
Untangling the Indonesian tangle net fishery: describing a data-poor fishery targeting large threatened rays (Order Batoidea)
|
zoology
|
On the efficacy of restoration in stream networks: comments, critiques, and prospective recommendations
|
ecology
|
Integrase-mediated differentiation circuits improve evolutionary stability of burdensome and toxic functions in E. coli
|
synthetic biology
|
Regulatory network-based imputation of dropouts in single-cell RNA sequencing data
|
bioinformatics
|
Resistance to aztreonam in combination with non-β-lactam β-lactamase inhibitors due to the layering of mechanisms in Escherichia coli identified following mixed culture selection.
|
microbiology
|
Attention Decorrelates Sensory and Motor Signals in the Mouse Visual Cortex
|
neuroscience
|
A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS
|
neuroscience
|
Fitness-related traits are maximized in recently introduced, slow-growing populations of an invasive clam: is this a response to strong r-selection?
|
ecology
|
O-glycosylation regulates plant developmental transitions downstream of miR156
|
plant biology
|
An Optimized Registration Workflow and Standard Geometric Space for Small Animal Brain Imaging
|
neuroscience
|
Uncovering the effects of Müllerian mimicry on the evolution of conspicuousness in colour patterns
|
evolutionary biology
|
On the cortical mapping function -- visual space, cortical space, and crowding
|
neuroscience
|
Memory for Individual Items is Related to Non-Reinforced Preference Change
|
neuroscience
|
Predation strategies of the bacterium Bdellovibrio bacteriovorus result in overexploitation and bottlenecks
|
microbiology
|
In the absence of reproductive isolation - Extensive gene flow after speciation
|
evolutionary biology
|
tRNAscan-SE 2.0: Improved Detection and Functional Classification of Transfer RNA Genes
|
bioinformatics
|
The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores
|
biophysics
|
Low centrosome numbers correlate with higher aggressivity in ovarian cancer
|
cancer biology
|
Protein and Lipid Mass Concentration Measurement in Tissues by Stimulated Raman Scattering Microscopy
|
bioengineering
|
Cholinergic modulation of dentate gyrus processing through dynamic reconfiguration of inhibitory circuits
|
neuroscience
|
Estimation of biodiversity metrics by environmental DNA metabarcoding compared with visual and capture surveys of river fish communities
|
ecology
|
Complex community-wide consequences of consumer sexual dimorphism
|
ecology
|
The regenerating skeletal muscle niche guides muscle stem cell self-renewal
|
cell biology
|
Synthetic design of farnesyl-electrostatic peptides for development of a protein kinase A membrane translocation switch
|
cell biology
|
First report of marine sponge Chelonaplysilla delicata (Demospongiae: Darwinellidae) from the Andaman Sea/Indian Ocean with a baseline information of epifauna on a mesophotic shipwreck
|
ecology
|
Quantitative analysis of ZFY and CTCF reveals dependent recognition of tandem zinc finger proteins.
|
genetics
|
Gene-experience correlation during cognitive development: Evidence from the Adolescent Brain Cognitive Development (ABCD) StudySM
|
neuroscience
|
Role of Water-bridged Interactions in Metal Ion Coupled Protein Allostery
|
biochemistry
|
An automated model reduction tool to guide the design and analysis of synthetic biological circuits
|
synthetic biology
|
Metacognitive awareness of difficulty in action selection: the role of the cingulo-opercular network
|
neuroscience
|
An optimized tissue clearing protocol for rat brain labeling, imaging, and high throughput analysis
|
neuroscience
|
Increasing plant group productivity through latent genetic variation for cooperation
|
plant biology
|
Muscle torques provide more sensitive measures of post-stroke movement deficits than joint angles.
|
neuroscience
|
Influenza-specific effector memory B cells predict long-lived antibody responses to vaccination in humans
|
immunology
|
Mutators drive evolution of multi-resistance to antibiotics
|
evolutionary biology
|
A Hessian-based decomposition characterizes how performance in complex motor skills depends on individual strategy and variability
|
neuroscience
|
Comparing statistical and mechanistic models to identify the drivers of mortality within a rear-edge beech population
|
ecology
|
Deconstructing taxa x taxa x environment interactions in the microbiota: A theoretical examination
|
ecology
|
Damped oscillations of the probability of random events followed by absolute refractory period: exact analytical results
|
neuroscience
|
Estimations of the weather effects on brain functions using functional MRI: a cautionary note
|
neuroscience
|
Secondary Structure Motifs Made Searchable to Facilitate the Functional Peptide Design
|
bioinformatics
|
Mitigating biomass composition uncertainties in flux balance analysis using ensemble representations
|
systems biology
|
Molecular Determinants of μ-Conotoxin KIIIA interaction with the Voltage-Gated Sodium Channel Nav1.7
|
biophysics
|
Deep learning does not outperform classical machine learning for cell-type annotation
|
bioinformatics
|
Regulatory regions in natural transposable element insertions drive interindividual differences in response to immune challenges in Drosophila
|
evolutionary biology
|
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