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Molecular Basis of the Activation and Dissociation of Dimeric PYL2 Receptor in Abscisic Acid Signaling
plant biology
Grazer behavior can regulate large-scale patterning of community states
ecology
High-resolution QTL mapping with Diversity Outbred mice identifies genetic variants that impact gut microbiome composition
genetics
Addressing the Embeddability Problem in Transition Rate Estimation
biophysics
Loss of intermediate filament IFB-1 reduces mobility, density and physiological function of mitochondria in C. elegans sensory neurons
cell biology
The Human Motor Cortex Contributes to Gravity Compensation to Maintain Posture and During Reaching
neuroscience
Humans can navigate complex graph structures acquired during latent learning
animal behavior and cognition
Mitochondrial fission is increased in macrophages during mROS production in response to S. pneumoniae
immunology
An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei
microbiology
Cross-Species association statistics for genome-wide studies of host and parasite polymorphism data
evolutionary biology
Protein yield is tunable by synonymous codon changes of translation initiation sites
bioinformatics
Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk
genomics
Choice-selective sequences dominate in cortical relative to thalamic inputs to the nucleus accumbens, providing a potential substrate for credit assignment
neuroscience
scAEspy: a tool for autoencoder-based analysis of single-cell RNA sequencing data
bioinformatics
The PRMT7-dependent methylation of shank2 modulates invasion-proliferation switching during breast cancer metastasis
cancer biology
Distinct neurocomputational mechanisms support informational and normative conformity
neuroscience
Cell-scale biophysical determinants of cell competition in epithelia
biophysics
Relating Global and Local Connectome Changes to Dementia and Targeted Gene Expression in Alzheimer's Disease
bioinformatics
Endosomal explosion induced by hypertonicity
biophysics
CrowdGO: machine learning and semantic similarity guided consensus Gene Ontology annotation
bioinformatics
Sorting motifs target the movement protein of ourmia melon virus to the trans-Golgi network and plasmodesmata
plant biology
Transcriptome computational workbench (TCW): analysis of single and comparative transcriptomes
bioinformatics
Unfolding and identification of membrane proteins in situ
biophysics
Decoding the sound of hand-object interactions in primary somatosensory cortex
neuroscience
Genomic insights into the Archaea inhabiting an Australian radioactive legacy site
microbiology
An R Package for Divergence Analysis of Omics Data
bioinformatics
Cholesterol recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: the case for TRKB
neuroscience
Talin-vinculin precomplex drives adhesion maturation by accelerated force transmission and vinculin recruitment
cell biology
Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration
neuroscience
THE COSTS AND BENEFITS OF BASAL INFECTION RESISTANCE VS DIVERSE IMMUNE PRIMING RESPONSES IN AN INSECT
evolutionary biology
Common breast cancer risk loci predispose to distinct tumor subtypes
genetics
Analysis of eukaryotic lincRNA sequences reveals signatures of repressed translation in species under strong selection
genomics
Priors, population sizes, and power in genome-wide hypothesis tests
genetics
CXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration
cancer biology
Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype
biophysics
Environmental and genetic factors cause atypical development of vocalizations in neonatal mice: analyses of neurodevelopmental disorder models using a novel unsupervised machine learning approach
neuroscience
Decoding the molecular landscape of the developing spatial processing system and production of entorhinal stellate cell-like cells by a direct programming approach.
developmental biology
Adaptational lags during periods of environmental change
evolutionary biology
Aquila_stLFR: diploid genome assembly basedstructural variant calling package for stLFRlinked-read
bioinformatics
GABA levels in ventral visual cortex decline with age and are associated with neural distinctiveness
neuroscience
Using target capture to address conservation challenges: population-level tracking of a globally-traded herbal medicine
genomics
Quantitative Single-Cell Proteomics as a Tool to Characterize Cellular Hierarchies
systems biology
Wheat inositol pyrophosphate kinase TaVIH2-3B modulates cell-wall composition for drought tolerance in Arabidopsis
plant biology
Meiotic budding yeast assemble bundled triple helices but not ladders
cell biology
Why are children so distractible? Development of attentional capacities and motor control from childhood to adulthood.
neuroscience
The fasciola cinereum subregion of the hippocampus is important for the acquisition of visual contextual memory
neuroscience
Motif elucidation in ChIP-seq datasets with a knockout control
bioinformatics
Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
neuroscience
Genome-wide discovery of hidden genes mediating known drug-disease association using KDDANet
bioinformatics
Adaptation and correlated fitness responses over two time scales in Drosophila suzukii populations evolving in different environments
evolutionary biology
Multi-scale systems genomics analysis predicts pathways, cell types and drug targets involved in normative human cognition variation
genomics
Age-related differences in white matter: Understanding tensor-based results using fixel-based analysis
neuroscience
High photosynthesis rate in the selected wild rice is driven by leaf anatomy mediating high Rubisco activity and electron transport rate
plant biology
A signaling axis involving CNOT3, Aurora B and ERK promotes mesendodermal differentiation of ES cells in response to FGF2 and BMP4
developmental biology
Contextual extinction of drug-associated discriminative stimuli fails to attenuate drug-vs-food choice in rhesus monkeys
neuroscience
Reconstruction of plant-pollinator networks from observational data
ecology
Deciphering Legionella effector delivery by Icm/Dot secretion system reveals a new role for c-diGMP signaling
microbiology
Sawfish, Read in Tooth and Saw: rostral teeth as endogenous chemical records of movement and life-history in a critically endangered species
ecology
Hybrid incompatibility is stronger in the presence of transposable elements in the Drosophila virilis clade
evolutionary biology
Conformation-dependent influences of hydrophobic amino acids in two in-register parallel β-sheet amyloids, an α-synuclein amyloid and a local structural model of PrPSc
molecular biology
Lineage-specific control of convergent differentiation by a Forkhead repressor
developmental biology
Phylogenomic Testing of Root Hypotheses
evolutionary biology
NLIMED: Natural Language Interface for ModelEntity Discovery in Biosimulation ModelRepositories
bioinformatics
Population-level sensitivity to landscape variables reflects individual-based habitat selection in a woodland bat species
ecology
The genetic landscape of Ethiopia: diversity, intermixing and the association with culture
genetics
Kin discrimination promotes horizontal gene transfer between unrelated strains in Bacillus subtilis
microbiology
Protein Design and Variant Prediction Using Autoregressive Generative Models
systems biology
Integration of brief light flashes varying in intensity and duration by the human circadian system
neuroscience
Mechanisms of distributed working memory in a large-scale network of macaque neocortex
neuroscience
Circadian protein regulation in the green lineage II. The clock gene circuit controls a phospho-dawn in Arabidopsis thaliana.
systems biology
IRG1 controls host responses to restrict Mycobacterium tuberculosis infection
immunology
Stress generation, relaxation and size control in confined tumor growth
biophysics
Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
neuroscience
LAB-AID (Laboratory Automated Interrogation of Data): an interactive web application for visualization of multi-level data from biological experiments
bioinformatics
High-level cognition during story listening is reflected in high-order dynamic correlations in neural activity patterns
neuroscience
MRI of Capn15 knockout mice and analysis of Capn15 distribution reveal possible roles in brain development and plasticity
neuroscience
Pulling the strings of cell cycle: a non-coding RNA, CcnA, modulates the master regulators CtrA and GcrA in Caulobacter crescentus
microbiology
Spatial and phylogenetic structure of Alpine stonefly community assemblages across seven habitats using DNA-species
evolutionary biology
Single-trial dynamics of competing reach plans in the human motor periphery
neuroscience
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice
neuroscience
Representations of complex contexts: A role for hippocampus
neuroscience
No effect of monetary reward in a visual working memory task
animal behavior and cognition
Learning Divisive Normalization in Primary Visual Cortex
neuroscience
An Erwinia amylovora inducible promoter for intragenic improvement of apple fire blight resistance
bioengineering
Most cancers carry a substantial deleterious load due to Hill-Robertson interference
evolutionary biology
More than Two Populations of Microtubules Comprise the Dynamic Mitotic Spindle
cell biology
Two faces of perceptual awareness during the attentional blink: Gradual and discrete
neuroscience
Mechanotransduction of strain regulates an invasive phenotype in newly transformed epithelial cells
biophysics
Evolutionary genetic integration of behavioural and endocrine components of the stress response
evolutionary biology
Discovery of a small molecule having both potent anti-fibrotic and anti-inflammatory capabilities
cell biology
B-SOiD: An Open Source Unsupervised Algorithm for Discovery of Spontaneous Behaviors
neuroscience
Accounting for RNA polymerase heterogeneity reveals state switching and two distinct long-lived backtrack states escaping through cleavage
biophysics
Cysteine crosslinking in native membranes establishes the transmembrane architecture of Ire1
biochemistry
Descending neocortical output critical for skilled forelimb movements is distributed across projection cell classes
neuroscience
Characterizing the Network Architecture of Emotion Regulation Neurodevelopment
neuroscience
In silico stress fibre content affects peak strain in cytoplasm and nucleus but not in membrane for uniaxial substrate stretch
biophysics
Astrovirus in Reunion Free-tailed Bat (Mormopterus francoismoutoui)
ecology
Mesoamerica is a cradle and the Atlantic Forest is a museum of Neotropical butterfly diversity: Insights from the evolution and biogeography of Brassolini (Lepidoptera: Nymphalidae)
evolutionary biology
Size matters, so does condition: the use of a body condition index reveals the costs and benefits of structural body size in an insect.
ecology
Spatio-temporal control of DNA replication by the pneumococcal cell cycle regulator CcrZ
microbiology