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Targeted gene correction and functional recovery in achondroplasia patient-derived iPSCs
|
developmental biology
|
PLETHORA-WOX5 interaction and subnuclear localisation control Arabidopsis root stem cell maintenance
|
plant biology
|
High-Throughput Translational Profiling with riboPLATE-seq
|
systems biology
|
Incorporating Gene Expression in Genome-wide Prediction of Chromatin Accessibility via Deep Learning
|
bioinformatics
|
Identification of neural oscillations and epileptiform changes in human brain organoids
|
neuroscience
|
Coordination through inhibition: control of stabilizing and updating circuits in spatial orientation working memory
|
neuroscience
|
The NTD of Eukaryotic Initiation Factor 4B Drives Yeast Translational Control in Response to Urea
|
molecular biology
|
Ten-eleven translocation 1 Mediated-DNA Hydroxymethylation is Required for Myelination and Remyelination in the Mouse Brain
|
neuroscience
|
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens
|
evolutionary biology
|
Broadband Signal Rather than Frequency-Specific Rhythms Underlie Prediction Error in the Primate Auditory Cortex
|
neuroscience
|
Cerebellar lesions disrupt spatial and temporal visual attention.
|
neuroscience
|
Host-microbiome protein-protein interactions capture mechanisms in human disease
|
microbiology
|
Species richness increases fitness differences, but does not affect niche differences
|
ecology
|
Non-selective response inhibition in Go/NoGo task: Bayesian analysis of fMRI data
|
neuroscience
|
Activation of G-protein coupled estradiol receptor 1 in the dorsolateral striatum attenuates preference for cocaine and saccharin in male but not female rats
|
neuroscience
|
NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants
|
genetics
|
Distinct roles for dopamine clearance mechanisms in regulating behavioral flexibility
|
neuroscience
|
Using the Tea Bag Index to determine how two human pharmaceuticals affect litter decomposition by aquatic microorganisms.
|
microbiology
|
CloneSig: Joint inference of intra-tumor heterogeneity and mutational signatures' activity in tumor bulk sequencing data
|
bioinformatics
|
A rationally designed oral vaccine induces Immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
|
immunology
|
Regulation of apical constriction via microtubule- and Rab11-dependent apical transport during tissue invagination
|
developmental biology
|
Ebselen attenuates mycobacterial virulence through inhibition of ESX-1 secretion
|
microbiology
|
Low-disturbance Farming Regenerates Healthy Deep Soil towards Sustainable Agriculture
|
ecology
|
Population structure of chum salmon and selection on the markers collected for stock identification
|
evolutionary biology
|
Stability of neocortical synapses across sleep and wake
|
neuroscience
|
Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring
|
neuroscience
|
Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice
|
microbiology
|
Automaticity in the reading circuitry
|
neuroscience
|
Towards Practical and Robust DNA-based Data Archiving Using "Yin-Yang Codec" System
|
synthetic biology
|
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
|
neuroscience
|
Genomic Background Governs Opposing Responses to Nalidixic Acid Upon Megaplasmid Acquisition in Pseudomonas
|
microbiology
|
Attenuated directed exploration during reinforcement learning in gambling disorder
|
neuroscience
|
LiGIoNs: A Computational Method for the Detection and Classification of Ligand-Gated Ion Channels
|
bioinformatics
|
Blinking Statistics and Molecular Counting in direct Stochastic Reconstruction Microscopy (dSTORM)
|
biophysics
|
Linear B-cell epitope prediction for in silico vaccine design: a performance review of methods available via command-line interface
|
bioinformatics
|
Matrix Inversion and Subset Selection (MISS): A novel pipeline for quantitative mapping of diverse cell types across the murine brain
|
neuroscience
|
Estradiol-induced progesterone synthesis develops post-puberty in the rostral hypothalamus and coincides with post-pubertal changes in the steroidogenic pathway in female mouse hypothalamic astrocytes
|
neuroscience
|
Unravelling the genetic architecture of musical rhythm: a large-scale genome-wide association study of beat synchronization
|
genetics
|
Integrative nascent RNA methods to reveal cell-type specific transcription programs in peripheral blood and its derivative cells
|
molecular biology
|
Temperature predicts the maximum tree-species richness and water and frost shape the residual variation
|
ecology
|
Trading Mental Effort for Confidence in the Metacognitive Control of Value-Based Decision-Making
|
neuroscience
|
A multi-measure approach for assessing the performance of fMRI preprocessing strategies in resting-state functional connectivity
|
neuroscience
|
Personalized single-cell networks: a framework to predict the response of any gene to any drug for any patient
|
systems biology
|
PharmOmics: A Species- and Tissue-specific Drug Signature Database and Online Tool for Drug Repurposing
|
systems biology
|
A small-molecule antagonist for the Tudor domain of SMN disrupts the interaction between SMN and RNAP II
|
biochemistry
|
Interrogating theoretical models of neural computation with emergent property inference
|
neuroscience
|
Metabolic signatures of regulation by phosphorylation and acetylation
|
systems biology
|
ERBB2 is a Key Mediator in Hearing Restoration in Noise-Deafened Young Adult Mice
|
neuroscience
|
Privacy-preserving quality control of neuroimaging datasets in federated environments
|
neuroscience
|
Long-term warming effects on the microbiome and nitrogen fixation of a common moss species in sub-Arctic tundra
|
microbiology
|
How to characterise shared space use networks
|
ecology
|
The minimum land area requiring conservation attention to safeguard biodiversity
|
ecology
|
Astrocyte-like glia-specific gene deathstar is crucial for normal development, adult locomotion and lifespan of male Drosophila
|
genetics
|
Mesmerize: a dynamically adaptable user-friendly analysis platform for 2D & 3D calcium imaging data.
|
neuroscience
|
Targeting cellular DNA damage responses in cancer: An in vitro-calibrated agent-based model simulating monolayer and spheroid treatment responses to ATR-inhibiting drugs
|
cancer biology
|
Characterising sensorimotor adaptation in Complex Regional Pain Syndrome
|
neuroscience
|
The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host-switching
|
genomics
|
Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis
|
neuroscience
|
Divergent sex-specific effects of an IgE receptor polymorphism: from immunity to health, and ultimately, fitness
|
ecology
|
Cellular Fitness Phenotypes of Cancer Target Genes from On-cobiology to Cancer Therapeutics
|
cancer biology
|
A comprehensive survey of developmental programs reveals a dearth of tree-like lineage graphs and ubiquitous regeneration
|
developmental biology
|
Advances in Spiral fMRI: A High-resolution Study with Single-shot Acquisition
|
neuroscience
|
Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages
|
genomics
|
Inhibition of both mutant and wild-type RAS-GTP in KRAS G12C colorectal cancer through cotreatment with G12C and EGFR inhibitors
|
cancer biology
|
Automated identification of maximal differential cell populations in flow cytometry data
|
bioinformatics
|
Beyond taxonomic identification: integration of ecological responses to a soil bacterial 16S rRNA gene database.
|
microbiology
|
Effective downregulation of BCR-ABL tumorigenicity by RNA targeted CRISPR-Cas13a
|
molecular biology
|
Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower
|
evolutionary biology
|
Frequency selectivity of persistent cortical oscillatory responses to auditory rhythmic stimulation
|
neuroscience
|
Recombination and selection against introgressed DNA
|
evolutionary biology
|
Predictive Coding Models for Pain Perception
|
neuroscience
|
Differential robustness to specific potassium channel deletions in midbrain dopaminergic neurons
|
neuroscience
|
Strand asymmetry influences mismatch resolution during single-strand annealing
|
genomics
|
Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
|
cell biology
|
RAF conformational autoinhibition and 14-3-3 proteins promote paradoxical activation
|
cancer biology
|
Integration of Odor-Induced Activity of Kenyon Cells in an Electrotonically Compact Drosophila Mushroom Body Output Neuron (MBON)
|
neuroscience
|
Effects of dopamine receptor antagonism and amphetamine-induced psychomotor sensitization on sign- and goal-tracking after extended training
|
neuroscience
|
Barley RIC157 is involved in RACB-mediated susceptibility to powdery mildew
|
plant biology
|
Using single visits into integrated occupancy models to make the most of existing monitoring programs
|
ecology
|
GraphProt2: A graph neural network-based method for predicting binding sites of RNA-binding proteins
|
bioinformatics
|
Temperature-induced prophage dictates evolution of virulence in bacteria
|
evolutionary biology
|
Bacterial quorum sensing allows graded and bimodal cellular responses to variations in population density
|
microbiology
|
Family History of Depression is Associated with Alterations in Task-Dependent Connectivity between the Cerebellum and Ventromedial Prefrontal Cortex
|
neuroscience
|
Predator complementarity dampens variability of phytoplankton biomass in a diversity-stability trophic cascade
|
ecology
|
Statistical power: implications for planning MEG studies
|
neuroscience
|
Low membrane fluidity triggers lipid phase separation and protein segregation in vivo
|
microbiology
|
Energy Expenditure during Cell Spreading Regulates the Stem Cells Responses to Matrix Stiffness
|
cell biology
|
The neural computation of human prosocial choices in complex motivational states
|
neuroscience
|
Distinct Processing of Selection and Execution Errors in Neural Signatures of Outcome Monitoring
|
neuroscience
|
Face familiarity detection with complex synapses
|
neuroscience
|
The metastable brain associated with autistic-like traits of typically developing individuals
|
neuroscience
|
Electrode pooling: How to boost the yield of switchable silicon probes for neuronal recordings
|
neuroscience
|
Constricted migration is associated with stable 3D genome structure differences in cancer cells
|
systems biology
|
Multi-Study Learning for Real-time Neurochemical Sensing in Humans using the "Study Strap Ensemble"
|
neuroscience
|
Linear reinforcement learning: Flexible reuse of computation in planning, grid fields, and cognitive control
|
neuroscience
|
Network potential identifies therapeutic miRNA cocktails in Ewings Sarcoma
|
systems biology
|
Dopamine and stress signalling interplay patterns social organization in mice
|
animal behavior and cognition
|
Mapping Human Pluripotent Stem Cell Derived Erythroid Differentiation by Single-Cell Transcriptome Analysis
|
developmental biology
|
Bacterial lipopolysaccharide induces settlement and metamorphosis in a marine larva
|
ecology
|
Cascading Epigenomic Analysis for Identifying Disease Genes from the Regulatory Landscape of GWAS Variants
|
bioinformatics
|
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