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Biophysical basis of cellular multi-specificity encoded in a model molecular switch
systems biology
The mechanisms of in vivo commensal control of Clostridioides difficile virulence
microbiology
Modeling gene expression evolution with EvoGeneX uncovers differences in evolution of species, organs and sexes
evolutionary biology
Different forms of variability could explain a difference between human and rat decision making
neuroscience
Mechanical control of morphogenetic robustness in an inherently challenging environment
developmental biology
Scanning electron microscopy preparation of the cellular actin cortex: a quantitative comparison between critical point drying and hexamethyldisilazane drying
biophysics
Protein sequence design with a learned potential
bioinformatics
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele
neuroscience
Lumbar corticospinal tract in rodents modulates sensory inputs but does not convey motor command
neuroscience
Subliminal perception can be predicted from prestimulus activity
neuroscience
Predictive feedback, early sensory representations and fast responses to predicted stimuli depend on NMDA receptors
neuroscience
Computed tomography reveals hip dysplasiain the extinct Pleistocene saber-tooth cat Smilodon
paleontology
Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons
immunology
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
bioinformatics
Bayesian cell-type deconvolution and gene expression inference reveals tumor-microenvironment interactions
genomics
RNA-binding protein Syncrip regulates Starvation-Induced Hyperactivity in adult Drosophila
genomics
4DNvestigator: Time Series Genomic Data Analysis Toolbox
bioinformatics
A silent disco: Persistent entrainment of low-frequency neural oscillations underlies beat-based, but not pattern-based temporal expectations
neuroscience
The formation of microbial exoskeletons is driven by a controlled calcium-concentrating subcellular niche
microbiology
Geographical and environmental contributions to genomic divergence in mangrove forests
evolutionary biology
A semi-empirical model of the aerodynamics of manoeuvring insect flight
biophysics
Trial-by-trial predictions of subjective time from human brain activity
neuroscience
Fundamental resource specialization of herbivorous butterflies decreases toward lower latitudes
ecology
Succination of Dihydrolipoyllysine Succinyltransferase by Fumarate Exacerbates Defective Mitochondrial ATP Production during Complex I Deficiency
biochemistry
Propranolol promotes bone formation and limits resorption through novel mechanisms during anabolic parathyroid hormone treatment in female C57BL/6J mice
physiology
Changes in partner traits drive variation in plant-nectar robber interactions across habitats
ecology
DLG2 knockout reveals neurogenic transcriptional programs underlying neuropsychiatric disorders and cognition
developmental biology
Design and demonstration in vitro of mouse-specific Transcranial Magnetic Stimulation coil
neuroscience
Choice can be predicted from populations of bursting neurons in superficial layers of monkey V1
neuroscience
Radius-Optimized Efficient Template Matching for Lesion Detection from Brain Images
neuroscience
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer
cancer biology
Highly Multiplexed Single-Cell Full-Length cDNA Sequencing of human immune cells with 10X Genomics and R2C2
genomics
Music-selective neural populations arise without musical training
neuroscience
Differential contributions of synaptic and intrinsic inhibitory currents to speech segmentation via flexible phase-locking in neural oscillators
neuroscience
Calcium-independent astrocytic lipid release modulates neuronal excitability
neuroscience
A population-level statistic for assessing Mendelian behavior of genotyping-by-sequencing data from highly duplicated genomes
bioinformatics
Engram reactivation during memory retrieval predicts long-term memory performance in aged mice
neuroscience
Structural analysis of Sulfolobus solfataricus TF55β chaperonin in open and filamentous states
biophysics
Increased fronto-temporal connectivity by modified melody in real music
neuroscience
Species coexistence in resource-limited patterned ecosystems is facilitated by the interplay of spatial self-organisation and intraspecific competition
ecology
Evolutionary and ecological processes influencing chemical defense variation in an aposematic and mimetic Heliconius butterfly
evolutionary biology
Phosphatidylinositol Acyl Chains Configure Priming and Activation of the NLRP3 Inflammasome
immunology
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
developmental biology
Conceptual knowledge affects early stages of visual mental imagery and object perception
neuroscience
Efficient Coding in the Economics of Human Brain Connectomics
neuroscience
A Connectivity-based Psychometric Prediction Framework for Brain-behavior Relationship Studies
neuroscience
Modular and distinct PlexinA4/Farp2/Rac1 signaling controls dendrite morphogenesis
neuroscience
De novo learning versus adaptation of continuous control in a manual tracking task
neuroscience
Positive selection and gene duplications in tumour suppressor genes reveal clues abouthow cetaceans resist cancer
evolutionary biology
Regeneration in adult Drosophila brain
neuroscience
The hippocampal formation as a hierarchical generative model supporting generative replay and continual learning
neuroscience
Flight demand and environmental niche are associated with molecular evolutionary rates in a large avian radiation
evolutionary biology
Genetic population structure constrains local adaptation in sticklebacks
evolutionary biology
Chronic Staphylococcus aureus infection is cured by theory-driven therapy
systems biology
Virtual connectomic datasets in Alzheimer's Disease and aging using whole-brain network dynamics modelling
neuroscience
A role for reward valuation in the serotonergic modulation of impulsivity
neuroscience
DNA damage and macrophage infiltration in the ovaries of the long-lived GH deficient Ames Dwarf and the short-lived bGH transgenic mice
physiology
A simple, cheap, and robust protocol for the identification of mating type in Saccharomyces cerevisiae
microbiology
Genome-wide discovery of lupus genetic risk variant allelic regulatory activity
genomics
A morphological trait involved in reproductive isolation between Drosophila sister species is sensitive to temperature
evolutionary biology
Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching
biochemistry
A signal of competitive dominance in mid-latitude herbaceous plant communities
ecology
Description of a widespread bacterial secretion system with chemically diverse substrates
microbiology
Desmosomes polarize mechanical signaling to govern epidermal tissue form and function
cell biology
Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging
pathology
Evidence of Absence Regression: A Binomial N-Mixture Model for Estimating Fatalities at Wind Power Facilities
ecology
Development of early postnatal inhibitory function in the mouse medial prefrontal and primary somatosensory cortex
neuroscience
Not only compulsivity: The SAPAP3-KO mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviors.
neuroscience
Disentangling the roles of neocortical alpha/beta and hippocampal theta/gamma oscillations in human episodic memory formation
neuroscience
Short hydrogen bonds enhance non-aromatic protein-related fluorescence
biophysics
Prolonged disturbance of proteostasis induces cellular senescence via temporal mitochondrial dysfunction and enhanced mitochondrial biogenesis in human fibroblasts
cell biology
Establishment of a Human RNA Pol II Pausing System and the Identification of O-GlcNAc Cycling Regulating Pol II Pausing and Elongation
biochemistry
Entropy of city street networks linked to future spatial navigation ability
neuroscience
Single molecule imaging reveals the collective and independent search mechanisms of cFos and cJun on DNA
biochemistry
Climate change will drive novel cross-species viral transmission
ecology
Adaptive divergence generates distinct plastic responses in two closely related Senecio species
evolutionary biology
TMEM184b is necessary for IL-31 induced itch
neuroscience
Schizophrenia Risk Alleles Often Affect The Expression of Many Genes and Each Gene May Have a Different Effect On The Risk; A Mediation Analysis.
genetics
Are skyline plot-based demographic estimates overly dependent on smoothing prior assumptions?
genetics
Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor
biophysics
Contrasting Effects of Western vs. Mediterranean Diets on Monocyte Inflammatory Gene Expression and Social Behavior in a Primate Model
genomics
MazeMaster: an open-source Python-based software package for controlling virtual reality experiments
neuroscience
Abnormal center of mass control during balance: a new biomarker of falls in people with Parkinson's disease
neuroscience
Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota
microbiology
Between-subject prediction reveals a shared representational geometry in the rodent hippocampus
neuroscience
Energetics of stochastic BCM type synaptic plasticity and storing of accurate information
neuroscience
Extreme hot weather has stronger impacts on avian reproduction in forests than in cities
ecology
The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective
bioinformatics
eQTL Catalogue: a compendium of uniformly processed human gene expression and splicing QTLs
genomics
The histone variant macroH2A1.1 regulates RNA Polymerase II paused genes within defined chromatin interaction landscapes.
genomics
Learning to Integrate an Artificial Sensory Device: Early Bayesian Integration and Conscious Perception
neuroscience
Dynamic landscape of protein occupancy across the Escherichia coli chromosome
systems biology
Insights into Cross-species Evolution of Novel Human Coronavirus SARS-CoV-2 and Defining Immune Determinants for Vaccine Development
microbiology
Interpretable detection of novel human viruses from genome sequencing data
bioinformatics
Loss and recovery of transcriptional plasticity after long-term adaptation to global change conditions in a marine copepod
evolutionary biology
CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference
bioinformatics
Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes
cell biology
Fitting drift-diffusion decision models to trial-by-trial data
animal behavior and cognition
Semantic and Prosodic Threat Processing in Trait Anxiety.
neuroscience
Understanding population structure in an evolutionary context: population-specific FST and pairwise FST
evolutionary biology