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Improvements to multi-offset adaptive optics scanning laser ophthalmoscopy for in vivo imaging of individual retinal ganglion cell layer neurons in humans
|
bioengineering
|
Relative water content consistently predicts drought mortality risk in seedling populations with different morphology, physiology, and times to death
|
plant biology
|
A vacuolar hexose transport is required for xylem development in the inflorescence stem of Arabidopsis.
|
plant biology
|
Removal of KCNQ2 from Parvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine
|
neuroscience
|
Disruptions in effort-based decision-making following acute optogenetic stimulation of ventral tegmental area dopamine cells
|
neuroscience
|
A sinusoidal transform of the visual field in cortical area V2
|
neuroscience
|
Families matter: Comparative genomics provides insight into the function of phylogenetically diverse sponge associated bacterial symbionts
|
microbiology
|
Sequential recognition of discrete export signals in flagellar subunits during bacterial Type III secretion
|
microbiology
|
Bacterial sirtuin CobB and PRPP synthase crosstalk in regulation of protein acetylation
|
molecular biology
|
Making the Most of Potential: Potential Games and Genotypic Convergence
|
evolutionary biology
|
Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
|
genetics
|
Interplay between the cell envelope and mobile genetic elements shapes gene flow in populations of a nosocomial pathogen.
|
evolutionary biology
|
Large and interacting effects of temperature and nutrient addition on stratified microbial ecosystems in a small, replicated, and liquid dominated Winogradsky column approach
|
microbiology
|
Dynamics of the compartmentalized Streptomyces chromosome during metabolic differentiation
|
microbiology
|
Robust integrated intracellular organization of the human iPS cell: where, how much, and how variable
|
cell biology
|
The role of mechanical interactions in EMT
|
biophysics
|
Uncovering the Organization of Neural Circuits with Generalized Phase Locking Analysis
|
neuroscience
|
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice
|
microbiology
|
Molnupiravir (EIDD-2801) inhibits SARS-CoV-2 replication and enhances the efficacy of favipiravir in a Syrian hamster infection model
|
microbiology
|
Direct differentiation of Dental Pulp Pluripotent-like Stem Cells differentiation into Hepatocyte-like Cells
|
cell biology
|
The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite
|
genomics
|
Detecting de novo mitochondrial mutations in angiosperms with highly divergent evolutionary rates
|
genetics
|
Defective myelination in an RNA polymerase IIImutant leukodystrophic mouse
|
neuroscience
|
Transcription factors drive opposite relationships between gene age and tissue specificity in male and female Drosophila gonads
|
evolutionary biology
|
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target
|
microbiology
|
Dual color mesoscopic imaging reveals spatiotemporally heterogeneous coordination of cholinergic and neocortical activity.
|
neuroscience
|
Coiled coil control of growth factor and inhibitor-dependent EGFR trafficking anddegradation
|
biochemistry
|
EVALUATING METHODS AND PROTOCOLS OF FERRITIN-BASED MAGNETOGENETICS
|
bioengineering
|
Conformational Ensembles of Non-Coding Elements in the SARS-CoV-2 Genome from Molecular Dynamics Simulations
|
biophysics
|
Molecular evolutionary trends and biosynthesis pathways in the Oribatida revealed by the genome of Archegozetes longisetosus
|
zoology
|
Enhancing Task fMRI Preprocessing via Individualized Model-Based Filtering of Intrinsic Activity Dynamics
|
neuroscience
|
Differences in neuronal numbers, morphology and developmental apoptosis in mice nigra provide experimental evidence of ontogenic origin of vulnerability to Parkinson disease
|
neuroscience
|
Ciliary neuropeptidergic signaling dynamically regulates excitatory synapses in postnatal neocortical pyramidal neurons
|
neuroscience
|
Increased prefrontal top-down control in older adults predicts motor performance and age-group association
|
neuroscience
|
Resonating neurons stabilize heterogeneous grid-cell networks
|
neuroscience
|
No behavioral evidence for rhythmic facilitation of perceptual discrimination
|
neuroscience
|
Regional structural-functional connectome coupling is heritable and associated with age, sex and cognitive scores in adults
|
neuroscience
|
Myogenin controls via AKAP6 non-centrosomal microtubule organizing center formation at the nuclear envelope
|
cell biology
|
Non-cell autonomous inhibition of the Shh pathway due to impaired cholesterol biosynthesis requires Ptch1/2
|
developmental biology
|
Improved estimation of phenotypic correlations using summary association statistics
|
genetics
|
Activity-based urinary biomarkers of response and resistance to checkpoint blockade immunotherapy
|
bioengineering
|
Efficacy and accuracy responses of DNA mini-barcodes in species identification under a supervised machine learning approach
|
bioinformatics
|
A pragmatic reevaluation of the efficacy of nonhuman primate optogenetics for psychiatry
|
neuroscience
|
A feature-based network analysis and fMRI meta-analysis reveal three distinct types of prosocial decisions
|
neuroscience
|
Cross-species Transcriptomic Network Analysis Reveals Links Between Ribosomal Protein Mutation and Cancer
|
genetics
|
Synchrony of Non-isochronous Signals in an Acoustically Communicating Katydid
|
animal behavior and cognition
|
Concurrent assessment of gait kinematics using marker-based and markerless motion capture
|
bioengineering
|
Assembling Long Accurate Reads Using Multiplex de Bruijn Graphs
|
bioinformatics
|
Functional crosstalk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5
|
biophysics
|
Integrative genomics identifies lncRNA regulatory networks across 1,044 pediatric leukemias and extra-cranial solid tumors
|
cancer biology
|
The Role of Human Platelet-Rich Plasma to Enhance the Differentiation from Adipose derived Mesenchymal Stem Cells into Cardiomyocyte: An Experimental Study
|
molecular biology
|
Manual Annotation of Genes within Drosophila Species: the Genomics Education Partnership protocol
|
genomics
|
SOMDE: A scalable method for identifying spatially variable genes with self-organizing map
|
bioinformatics
|
Signal processing capacity of the cellular sensory machinery regulates the accuracy of chemotaxis under complex cues
|
biophysics
|
Stimulus-dependent representational drift in primary visual cortex
|
neuroscience
|
Cognitive and GABAergic protection by hAPPSw,Ind and hTauVLW coexpression: a model of Non-Demented with Alzheimer's disease Neuropathology
|
neuroscience
|
Evaluation of seasonal dynamics of fungal DNA assemblages in a flow-regulated stream in a restored forest using eDNA metabarcoding
|
ecology
|
Developmental effects on pattern visual evoked potentials characterized by principal component analysis
|
neuroscience
|
Temporal Scaling of Human Scalp-Recorded Potentials During Interval Estimation
|
neuroscience
|
Identification of a family of Vibrio type III secretion system effectors that contain a conserved serine/threonine kinase domain
|
microbiology
|
A Synthetic Transcription Platform for Programmable Gene Expression in Mammalian Cells
|
synthetic biology
|
Hippocampal cells multiplex positive and negative engrams
|
neuroscience
|
Target2DeNovoDrugPropMax : a novel programmatic tool incorporating deep learning and in silico methods for automated de novo drug design for any target of interest
|
bioinformatics
|
Optogenetic inhibition and activation of Rac and Rap1 using a modified iLID system
|
synthetic biology
|
A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
|
microbiology
|
Evolution of the recombination regulator PRDM9 in minke whales
|
genetics
|
Measuring Compound Eye Optics with Microscope and MicroCT Images
|
neuroscience
|
Bridges, not walls: the hippocampus builds narrative memories across distant events
|
neuroscience
|
A new method shows that a minority of liver-localized CD8 T cells display hard-to-detect attraction to Plasmodium-infected hepatocytes
|
immunology
|
Uncovering complementary sets of variants for predicting quantitative phenotypes
|
bioinformatics
|
Physiological and transcriptomic response of Medicago truncatula to high and low benefit mycorrhizal fungi
|
plant biology
|
Pioneer activity of an oncogenic fusion transcription factor at inaccessible chromatin
|
genomics
|
Toward a universal model for spatially structured populations
|
evolutionary biology
|
Gene family evolution underlies cell type diversification in the hypothalamus of teleosts
|
cell biology
|
Identification of a Golgi-localized peptide encoded by the CENP-R transcript
|
cell biology
|
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor
|
bioinformatics
|
5-HT2C receptors regulate the balance between instrumental vigour and restraint
|
neuroscience
|
Translational control as a novel regulator of gradient sensing and chemotropism in yeast
|
cell biology
|
Plasticity of fibroblast transcriptional response to physical and biochemical cues revealed by dynamic network analysis
|
systems biology
|
Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice
|
neuroscience
|
Analysing economic costs of invasive alien species with the invacost R package
|
ecology
|
Large-scale geographic survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa
|
evolutionary biology
|
Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro
|
microbiology
|
Transcription of macromolecular N degrading genes provides a window into organic nitrogen decomposition in soil
|
microbiology
|
Pathogenic and Indigenous Denitrifying Bacteria are Transcriptionally Active and Key Multi-Antibiotic Resistant Players in Wastewater Treatment Plants
|
microbiology
|
Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity
|
neuroscience
|
Public good exploitation in natural bacterioplankton communities
|
microbiology
|
Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion H69/V70
|
microbiology
|
Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation in Escherichia coli
|
molecular biology
|
Decomposing the sources of SARS-CoV-2 fitness variation in the United States
|
evolutionary biology
|
Genomic surveillance framework and global population structure for Klebsiella pneumoniae
|
genomics
|
The SEQC2 Epigenomics Quality Control (EpiQC) Study: Comprehensive Characterization of Epigenetic Methods, Reproducibility, and Quantification
|
genomics
|
Multiplex genotyping method to validate the multiallelic genome editing outcomes using machine learning-assisted long-read sequencing
|
genomics
|
Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation.
|
developmental biology
|
Paracrine behaviors arbitrate parasite-like interactions between tumor subclones
|
cancer biology
|
A developmental transition in the sensory coding of limb kinematics in primary motor cortex
|
neuroscience
|
Soft sweeps predominate recent positive selection in bonobos (Pan paniscus) and chimpanzees (Pan troglodytes)
|
genomics
|
DeepCellState: an autoencoder-based framework for prediction of cell type specific transcriptional states induced by drug treatment
|
bioinformatics
|
Informing NMR experiments with molecular dynamics simulations to characterize the dominant activated state of the KcsA ion channel
|
biophysics
|
STUB1 is an intracellular checkpoint for interferon gamma sensing
|
cancer biology
|
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