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Age-related decline in cortical inhibitory tone strengthens motor memory
|
neuroscience
|
Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs
|
neuroscience
|
Mouse and Human Antibodies that Bind HLA-E-Leader Peptide Complexes and Enhance NK Cell Cytotoxicity
|
immunology
|
An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer
|
cancer biology
|
Adaptation of Bacillus thuringiensis to plant colonisation affects differentiation and toxicity
|
microbiology
|
MASiVar: Multisite, Multiscanner, and Multisubject Acquisitions for Studying Variability in Diffusion Weighted Magnetic Resonance Imaging
|
bioengineering
|
Identification of a High-frequency Intra-host SARS-CoV-2 spike Variant with Enhanced Cytopathic and Fusogenic Effect
|
bioinformatics
|
Hebbian plasticity in parallel synaptic pathways: A circuit mechanism for systems memory consolidation
|
neuroscience
|
Efferent control of hearing sensitivity and protection via inner ear supporting cells
|
neuroscience
|
Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide
|
biophysics
|
Quadratic Mutual Information estimation of mouse dLGN receptive fields reveals asymmetry between ON and OFF visual pathways
|
neuroscience
|
Spatial distribution of local patch extinctions drives recovery dynamics in metacommunities
|
ecology
|
Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments
|
bioinformatics
|
In vivo Evaluation and in silico Prediction of the Toxicity of Drepanoalpha Hard capsules
|
pharmacology and toxicology
|
Co-regulating many properties by co-adjusting few ion channels increases ion channel correlations and the risk of regulation failure
|
neuroscience
|
Easy to interpret Coordinate Based Meta-Analysis of neuroimaging studies: Analysis of Brain Coordinates (ABC)
|
neuroscience
|
Predicting lineage-specific differences in open chromatin across dozens of mammalian genomes
|
genetics
|
De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex
|
biochemistry
|
Manifold learning analysis suggests novel strategies for aligning single-cell multi-modalities and revealing functional genomics for neuronal electrophysiology
|
bioinformatics
|
A-to-I mRNA editing in a ferric siderophore receptor improves competition for iron in Xanthomonas oryzae
|
microbiology
|
Dynamics of cell mass and size control in multicellular systems and the human body
|
cell biology
|
Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR
|
genetics
|
CYRI-A regulates macropinocytic cup maturation and mediates integrin uptake, limiting invasive migration
|
cell biology
|
Activation of central 5HT2A receptor in brain inhibited the seizure-induced respiratory arrest in the DBA/1 mouse SUDEP model
|
neuroscience
|
Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among bloodstream isolates at a United States academic medical center
|
microbiology
|
Sinorhizobium meliloti functions required for resistance to antimicrobial NCR peptides and bacteroid differentiation
|
microbiology
|
Social network architecture and the tempo of cumulative cultural evolution
|
evolutionary biology
|
Task dependence of neural representations of scene attributes but not scene categories in the prefrontal cortex
|
neuroscience
|
The ascending arousal system promotes optimal performance through meso-scale network integration in a visuospatial attentional task
|
neuroscience
|
Distinct neural representations of content and ordinal structure in auditory sequence memory
|
neuroscience
|
Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4+ T cells
|
immunology
|
Commensal Microbiota Regulates Skin Barrier Function And Repair Via Signaling Through The Aryl Hydrocarbon Receptor
|
microbiology
|
Redefining the role of Ca2+-permeable channels in photoreceptor degeneration using diltiazem
|
neuroscience
|
Genotyping common, large structural variations in 5,202 genomes using pangenomes, the Giraffe mapper, and the vg toolkit
|
bioinformatics
|
Cancer-specific overmethylation of histone H3 lysines is linked with methionine addiction and malignancy
|
cancer biology
|
Genomic basis of drought resistance in Fagus sylvatica
|
plant biology
|
Genetically Engineered Proportional-Integral Feedback Controllers for Robust Perfect Adaptation in Mammalian Cells
|
synthetic biology
|
Transient grb10a Knockdown Permanently Alters Growth, Cardiometabolic Phenotype and the Transcriptome in Danio rerio
|
developmental biology
|
Composition Wheels: Visualizing dissolved organic matter using common composition metrics across a variety of Canadian Ecozones
|
ecology
|
Network reconstruction and modelling made reproducible with moped
|
bioinformatics
|
Whole genome sequencing of nearly isogeneic WMI and WLI inbred rats identifies genes potentially involved in depression
|
bioinformatics
|
Functional maps of the primate cortex revealed by through-skull wide-field optical imaging
|
neuroscience
|
Drawing the Borders of Olfactory Space
|
neuroscience
|
Neural mechanisms underlying the temporal control of sequential saccade planning in the frontal eye fields
|
neuroscience
|
Transcriptomic profiling and microsatellite identification in cobia (Rachycentron canadum), using high throughput RNA-sequencing
|
bioinformatics
|
Attentional Modulation of Hierarchical Speech Representations in a Multitalker Environment
|
neuroscience
|
The cost of attentional reorienting on conscious visual perception: an MEG study
|
neuroscience
|
Shaping sustainable harvest boundaries for marine populations despite estimation bias
|
ecology
|
YieldNet: A Convolutional Neural Network for Simultaneous Corn and Soybean Yield Prediction Based on Remote Sensing Data
|
bioinformatics
|
Visualizing subcellular structures in neuronal tissue with expansion microscopy
|
neuroscience
|
Somatic Cell Nuclear Transfer Embryos Show Massive Dysregulation of Genes Involved in Transcription Pathway
|
bioinformatics
|
Scientific publications and COVID-19 "research pivots" during the pandemic: An initial bibliometric analysis
|
scientific communication and education
|
Development of a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment.
|
neuroscience
|
Dendritic signal integration in a Drosophila Mushroom Body Output Neuron (MBON) essential for learning and memory
|
neuroscience
|
Strategic trade-offs between choice biases and accuracy for decisions based on asymmetric, rare evidence
|
neuroscience
|
Global transcriptomics reveals specialized roles for splicing regulatory proteins in the macrophage innate immune response
|
immunology
|
A new hypothesis for type 1 diabetes risk: The at-risk allele at rs3842753 associates with increased beta cell INS mRNA in a meta-analysis of single cell RNA sequencing data
|
cell biology
|
Sequence determinants of the aggregation of proteins within condensates generated by liquid-liquid phase separation
|
cell biology
|
Heterogeneity of monocyte subsets and susceptibility to influenza virus contribute to inter-population variability of protective immunity
|
genomics
|
A massively multi-scale approach to characterising tissue architecture by synchrotron micro-CT applied to the human placenta
|
bioengineering
|
Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate
|
cell biology
|
DNA-sequence dependent positioning of the linker histone in a nucleosome: a single-pair FRET study
|
biophysics
|
Pre-Implantation Alcohol Exposure Induces Lasting Sex-Specific DNA Methylation Programming Errors in the Developing Forebrain
|
developmental biology
|
L-DOPA modulates activity in the vmPFC, Nucleus Accumbens and VTA during threat extinction learning in humans
|
neuroscience
|
Joint species distributions reveal the combined effects of host plants, abiotic factors and species competition as drivers of species abundances in fruit flies
|
ecology
|
Comprehensive analysis of Japanese archipelago population history by detecting ancestry-marker polymorphisms without using ancient DNA data
|
evolutionary biology
|
Oscillatory tracking of pseudo-rhythmic speech is constrained by linguistic predictions
|
neuroscience
|
Quantifying phase separation property of chromatin associated proteins under physiological conditions using anti-1,6-hexanediol index
|
cell biology
|
Cortical depth-dependent human fMRI of resting-state networks using EPIK
|
neuroscience
|
The convergence and divergence of episodic and semantic functions across lateral parietal cortex
|
neuroscience
|
Systematic comparison of incomplete-supervision approaches for biomedical imaging classification
|
bioinformatics
|
Lexical frequency and sentence context influence the brain's response to single words
|
neuroscience
|
Moving pictures: Reassessing docking experiments with a dynamic view of protein interfaces
|
biochemistry
|
Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism
|
cell biology
|
Structural basis of human protein disulfide isomerase flexibility revealed by single-molecule FRET
|
biophysics
|
Spinal cord associative plasticity improves forelimb sensorimotor function after cervical injury
|
neuroscience
|
Reducing interaural tonotopic mismatch preserves binaural unmasking in cochlear implant simulations of single-sided deafness
|
neuroscience
|
Applications of the indole-alkaloid gramine shape the prokaryotic microbiota thriving at the barley root-soil interface
|
plant biology
|
A holobiont view of island biogeography: unraveling patterns driving the nascent diversification of a Hawaiian spider and its microbial associates
|
evolutionary biology
|
Morphological changes in the mandibles accompany the defensive behavior of Indiana mite biting honey bees against Varroa destructor
|
animal behavior and cognition
|
Distant Residues Modulate Conformational Opening in SARS-CoV-2 Spike Protein
|
biophysics
|
An empirical evaluation of functional alignment using inter-subject decoding
|
neuroscience
|
Engineered receptor binding domain immunogens elicit pan-sarbecovirus neutralizing antibodies
|
immunology
|
Neuropredictome: a data-driven predictome for cognitive, psychiatric, medical, and lifestyle factors on the brain
|
neuroscience
|
Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE-2 in vitro
|
microbiology
|
A Draft Reference Genome for Hirudo verbana, the Medicinal Leech
|
genomics
|
Decoding Study-Independent Mind-Wandering from EEG using Convolutional Neural Networks
|
neuroscience
|
Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
|
immunology
|
Mechanisms for Communicating in a Marmoset "Cocktail Party"
|
neuroscience
|
Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate.
|
developmental biology
|
The Senescence-Associated-Secretory-Phenotype induced by centrosome amplification constitutes a pathway that activates Hypoxia-Inducible-Factor-1α.
|
cell biology
|
Does arsenic contamination affect DNA methylation patterns in a wild bird population? An experimental approach
|
ecology
|
Universal Spectrum Identifier for mass spectra
|
bioinformatics
|
A nanodomain anchored-scaffolding complex is required for PI4Kα function and localization in plants
|
plant biology
|
Rapid assembly of a polar network architecture drives efficient actomyosin contractility
|
cell biology
|
Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
|
neuroscience
|
A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
|
neuroscience
|
Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
|
immunology
|
A Machine Learning Model of Microscopic Agglutination Test for Diagnosis of Leptospirosis
|
microbiology
|
A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor
|
biochemistry
|
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