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Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
|
neuroscience
|
Short linear motif based interactions and dynamics of the ezrin, radixin, moesin and merlin FERM domains
|
biochemistry
|
MarcoPolo: a clustering-free approach to the exploration of differentially expressed genes along with group information in single-cell RNA-seq data
|
bioinformatics
|
A novel, ataxic mouse model of Ataxia Telangiectasia caused by a clinically relevant nonsense mutation
|
neuroscience
|
The Drosophila Baramicin polypeptide gene protects against fungal infection
|
immunology
|
Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
|
developmental biology
|
SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data
|
bioinformatics
|
Sex differences and similarities in the neuroimmune response to central administration of poly I:C
|
neuroscience
|
Universal constraints on protein evolution in the long-term evolution experiment with Escherichia coli
|
evolutionary biology
|
Metabolic differentiation of co-occurring Accumulibacter clades revealed through genome-resolved metatranscriptomics
|
genomics
|
The Selenoprotein P 3' untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation
|
molecular biology
|
Regulation of Dopamine D1 Receptor Signaling at the Golgi Apparatus by a Low Affinity Dopamine Transporter
|
cell biology
|
Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
|
cancer biology
|
Beyond fear centers: a distributed fMRI-based neuromarker for the subjective experience of fear
|
neuroscience
|
Demogenomic modeling of the timing and the processesof early European farmers differentiation
|
evolutionary biology
|
Integrating long-range regulatory interactions to predict gene expression using graph convolutional networks
|
bioinformatics
|
Predicting perturbation effects from resting state activity using functional causal flow
|
neuroscience
|
Crystal Structure of a Retroviral Polyprotein:Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)
|
biophysics
|
The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds highlight MAX2 dependent and independent pathways
|
plant biology
|
High-throughput characterization of 309 photocrosslinker-bearing ASIC1a variants maps residues critical for channel function and pharmacology
|
biophysics
|
Memory Transfer of Random Time Patterns Across Modalities
|
neuroscience
|
Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex-dependent endocytosis
|
cell biology
|
Mapping Epigenetic Divergence in the Massive Radiation of Lake Malawi Cichlid Fishes
|
genomics
|
LinearTurboFold: Fast Folding and Alignment for RNA Homologs with Applications to Coronavirus
|
bioinformatics
|
Fever temperatures impair hemolysis caused by strains of Escherichia coli and Staphylococcus aureus
|
microbiology
|
Snowball Earths, population bottlenecks, and the evolution of marine photosynthetic bacteria
|
microbiology
|
Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
|
developmental biology
|
A mixed model approach for estimating drivers of microbiota community composition and differential taxonomic abundance
|
evolutionary biology
|
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
|
biochemistry
|
Emerging Concern of Scientific Fraud: Deep Learning and Image Manipulation
|
scientific communication and education
|
Disease specific alterations in the olfactory mucosa of patients with Alzheimer's disease
|
neuroscience
|
Glycolic acid protects neurons against ischemia in vitro and in two animal models of stroke
|
neuroscience
|
Acetylcholine Signaling Genes are Required for Cocaine-Stimulated Egg Laying in Caenorhabditis elegans
|
neuroscience
|
Separation and enrichment of sodium-motile bacteria using cost-effective microfluidics.
|
microbiology
|
Adsorption of Azo Dyes by a Novel Bio-Nanocomposite Based on Whey Protein Nanofibrils and Nano-clay: Equilibrium Isotherm and Kinetic Modeling
|
bioengineering
|
Chromatin Fiber Folding Represses Transcription and Loop Extrusion in Quiescent Cells
|
molecular biology
|
Cortical processing of reference in language revealed by computational models
|
neuroscience
|
The structural connectome constrains fast brain dynamics
|
neuroscience
|
Dissecting genomic determinants of positive selection with an evolution-guided regression model
|
evolutionary biology
|
SpheroidPicker: An Automated 3D cell culture manipulator robot using deep learning
|
bioengineering
|
SequenceBouncer: A method to remove outlier entries from a multiple sequence alignment
|
evolutionary biology
|
distinct: a novel approach to differential distribution analyses
|
bioinformatics
|
Weak vestibular response in persistent developmental stuttering and implications for own voice identification
|
biophysics
|
Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses.
|
neuroscience
|
Sparse Epistatic Regularization of Deep Neural Networks for Inferring Fitness Functions
|
bioinformatics
|
Broad-spectrum antiviral activity of 3D8, a nucleic acid-hydrolyzing single chain variable fragment (scFv), targeting SARS-CoV-2 and multiple coronaviruses in vitro
|
microbiology
|
Generating complex patterns of gene expression without regulatory circuits
|
synthetic biology
|
Efficient GNE myopathy disease modeling with mutation specific phenotypes in human pluripotent stem cells by base editors
|
developmental biology
|
A convolutional neural-network framework for modelling auditory sensory cells and synapses
|
systems biology
|
Monitoring single-cell dynamics of entry into quiescence during an unperturbed lifecycle
|
cell biology
|
Benchmarking metagenomic classification tools for long-read sequencing data
|
bioinformatics
|
Environment-driven reprogramming of gamete DNA methylation occurs during maturation and is transmitted intergenerationally in salmon
|
evolutionary biology
|
How ancient forest fragmentation and riparian connectivity generate high levels of genetic diversity in a micro-endemic Malagasy tree
|
genomics
|
Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
|
microbiology
|
Patterns and Causes of Signed Linkage Disequilibria in Flies and Plants
|
genomics
|
Adaptive divergence and the evolution of hybrid trait mismatch in threespine stickleback
|
evolutionary biology
|
Orthogonal targeting of KDM6A/B and HDACs mediates potent therapeutic effects in IDH1-mutant glioma
|
cancer biology
|
Ethanolamine phosphate on the second mannose as bridge in GPI anchored proteins: Towards understanding inherited PIGG deficiency
|
molecular biology
|
A comparative study of data integration methods, integrating genetic association and functional annotation summary statistics
|
genetics
|
Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for neural repair
|
neuroscience
|
Establishment of Multi-stage Intravenous Self-administration in Mice
|
neuroscience
|
Plant provenance affects pollinator network: implications for ecological restoration
|
ecology
|
CICLOP: A Robust, Faster, and Accurate Computational Framework for Protein Inner Cavity Detection
|
bioinformatics
|
Robotic Search for Optimal Cell Culture in Regenerative Medicine
|
systems biology
|
Revisiting the Neural Architecture of Adolescent Decision-Making: Univariate and Multivariate Evidence for System-Based Models
|
neuroscience
|
FrustratometeR: an R-package to compute Local frustration in protein structures, point mutants and MD simulations
|
bioinformatics
|
Predicting the impact of sequence motifs on gene regulation using single-cell data
|
bioinformatics
|
A Non-Genetic, Cell Cycle Dependent Mechanism of Platinum Resistance in Lung Adenocarcinoma
|
cell biology
|
An initial 'snapshot' of sensory information biases the likelihood and speed of subsequent changes of mind
|
animal behavior and cognition
|
Nonlinear Stability Analysis for Artificial Kidney Multi-compartmental Models
|
bioengineering
|
Fast and sensitive taxonomic assignment to metagenomic contigs
|
bioinformatics
|
When less feels stronger: Earliest cortical responses differentially reflect stimulus intensity and neural excitability
|
neuroscience
|
Overexpressed microrna-129-5p reverses CCl4-Induced hepatic fibrosis by suppressing PEG3 expression and the NF-κB signaling pathway
|
pharmacology and toxicology
|
Whole-brain dynamics of human sensorimotor adaptation
|
neuroscience
|
Quantifying the relevance of alternative stable states in many-species food webs
|
ecology
|
Unveiling functions of the visual cortex using task-specific deep neural networks
|
neuroscience
|
Establishment of Culex modestus in Belgium and a glance into the virome of Belgian mosquito species
|
microbiology
|
3D super-resolution fluorescence microscopy maps the variable molecular architecture of the Nuclear Pore Complex
|
cell biology
|
Tackling the phylogenetic conundrum of Hydroidolina (Cnidaria: Medusozoa: Hydrozoa) by assessing competing tree topologies with targeted high-throughput sequencing.
|
evolutionary biology
|
Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
|
genomics
|
Human induced pluripotent stem cell-derived vessels as dynamic atherosclerosis model on a chip
|
bioengineering
|
The impact of phenotypic heterogeneity of tumour cells on treatment and relapse dynamics
|
evolutionary biology
|
Unheeded SARS-CoV-2 protein? Look deep into negative-sense RNA
|
bioinformatics
|
Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterised proteins
|
bioinformatics
|
Linear integration of sensory evidence over space and time underlies face categorization
|
neuroscience
|
Diverse molecular mechanisms contribute to differential expression of human duplicated genes
|
genomics
|
Investigations into modifications of neuromuscular physiology by axonal transport disruptions in Drosophila SOD1 mutants
|
neuroscience
|
Dynamic decision policy reconfiguration under outcome uncertainty
|
neuroscience
|
Jack-of-all-trades paradigm meets long-term data: generalist herbivores are more widespread and locally less abundant
|
ecology
|
Characterisation and chemometric evaluation of 17 elements in ten seaweed species from Greenland
|
biochemistry
|
Differential Contribution of Dopaminergic Transmission at D1- and D2-like Receptors to Cost/Benefit Evaluation for Motivation in Monkeys
|
neuroscience
|
PP2A-Cdc55 phosphatase coordinates actomyosin ring contraction and septum formation during cytokinesis
|
cell biology
|
Predicting Brain Regions Related to Alzheimer's Disease Based on Global Feature
|
neuroscience
|
Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos
|
developmental biology
|
De novo activated transcription of insertd foreign coding sequences is inheritable in the plant genome
|
evolutionary biology
|
Plant genome response to incoming coding sequences: stochastic transcriptional activation independent of integration loci
|
evolutionary biology
|
Continuous cis-regulatory changes in an advantageous gene are linked with adaptive radiation in cichlid fishes
|
evolutionary biology
|
Diagnostic design with machine learning model-based optimization
|
genomics
|
First demonstration of the FLASH effect with ultrahigh dose-rate high-energy X-rays
|
cancer biology
|
Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
|
molecular biology
|
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