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TIGA: Target illumination GWAS analytics
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bioinformatics
|
A Markov Random Field Model for Network-based Differential Expression Analysis of Single-cell RNA-seq Data
|
bioinformatics
|
Costs of choosiness can promote reproductive isolation in parapatry
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evolutionary biology
|
ACE2-Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker
|
microbiology
|
Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19
|
immunology
|
Identifying and prioritizing potential human-infecting viruses from their genome sequences
|
ecology
|
Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape
|
genomics
|
Local topology, bifurcations and mutation hot-spots in proteins with SARS-CoV-2 spike protein as an example
|
biophysics
|
The chemotherapeutic drug methotrexate selects for antibiotic resistance
|
microbiology
|
A practical PPE decontamination method using warm air and ambient humidity
|
microbiology
|
Homemade Bread: Repurposing an Ancient Technology for in vitro Tissue Engineering
|
bioengineering
|
MUNIn (Multiple sample UNifying long-range chromatin Interaction detector): a statistical framework for identifying long-range chromatin interactions from multiple samples
|
genetics
|
Investigation of reward learning and feedback sensitivity in non-clinical participants with a history of early life stress
|
neuroscience
|
Sex-specific lipid profiles in muscle of Atlantic salmon juveniles
|
molecular biology
|
Beating your neighbor to the berry patch
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evolutionary biology
|
A model of resource partitioning between foraging bees based on positive and negative associations
|
animal behavior and cognition
|
Epidural Electrical Stimulation of the Cervical Dorsal Roots Restores Voluntary Arm Control In Paralyzed Monkeys
|
bioengineering
|
Automatic wound detection and size estimation using deep learning algorithms
|
bioinformatics
|
Evaluation of feeding behaviour traits to predict efficiency traits in pigs using partial least square regression
|
physiology
|
Caspases switch off m6A RNA modification pathway to reactivate a ubiquitous human tumor virus
|
microbiology
|
Flexible fitting of PROTAC concentration-response curves with changepoint Gaussian Processes
|
cell biology
|
Pseudoreplication in genomics-scale datasets
|
genetics
|
Stimulus-specific plasticity in human visual gamma-band activity and functional connectivity
|
neuroscience
|
The Impact of Neuronal Structure on Cortical Network Architecture
|
neuroscience
|
Community composition of microbial microcosms follows simple assembly rules at evolutionary timescales
|
microbiology
|
Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severecases
|
molecular biology
|
Spatial and Temporal Localization of SPIRRIG and WAVE/SCAR Reveal Roles for These Proteins in Actin-Mediated Root Hair Development
|
plant biology
|
The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
|
developmental biology
|
Characterization and significance of extracellular polymeric substances, reactive oxygen species, and extracellular electron transfer in methanogenic biocathode
|
bioengineering
|
Bayesian modeling of skewed X inactivation ingenetically diverse mice identifies a novel Xce allele associated with copy number changes
|
genetics
|
Sensitizing Staphylococcus aureus to antibacterial host defense by decoding and blocking the lipid flippase MprF
|
microbiology
|
RNA polymerase backtracking results in the accumulation of fission yeast condensin at active genes
|
cell biology
|
SMC Complexes Are Guarded by the SUMO Protease Ulp2 Against SUMO-Chain-Mediated Turnover
|
cell biology
|
An open-access volume electron microscopy atlas of whole cells and tissues
|
cell biology
|
Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
|
genomics
|
Synaptic plasticity regulated by phosphorylation of PSD-95 Serine 73 in dorsal CA1 is required for contextual fear extinction
|
neuroscience
|
Mammary ductal epithelium controls cold-induced adipocyte thermogenesis
|
cell biology
|
Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures
|
biophysics
|
Inter- and intra-tumor heterogeneity in EMT states confers functional diversity in cells that lead collective invasion.
|
cancer biology
|
precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
|
bioinformatics
|
Hybrid Clustering of single-cell gene-expression and cell spatial information via integrated NMF and k-means
|
bioinformatics
|
Anatomic position determines oncogenic specificity in melanoma
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cancer biology
|
Learning from Failure: Action Performance Errors Stimulate Intentional Strategies, Not Implicit Learning
|
neuroscience
|
TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis
|
immunology
|
Mayaro Virus Infection Elicits an Innate Immune Response and Represses Autophagy in Anopheles stephensi
|
microbiology
|
Predictive attenuation of touch and tactile gating are distinct perceptual phenomena
|
neuroscience
|
Biotic homogenisation in bird communities leads to large-scale changes in species associations
|
ecology
|
Triplex and other DNA motifs show motif-specific associations with mitochondrial DNA deletions and species lifespan.
|
bioinformatics
|
Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts
|
cell biology
|
Spontaneous thalamic activity modulates the cortical innervation of the primary visual nucleus of the thalamus
|
neuroscience
|
Active Participation of Membrane Lipids in Inhibition of Multidrug Transporter P-Glycoprotein
|
biophysics
|
Noradrenergic Regulation of Two-Armed Bandit Performance
|
neuroscience
|
Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis
|
neuroscience
|
Automated Segmentation of Amyloid-β Stained Whole Slide Images of Brain Tissue
|
neuroscience
|
Competition within low-density bacterial populations as an unexpected factor regulating carbon decomposition in bulk soil
|
ecology
|
Combining climatic and genomic data improves range-wide tree height growth prediction in a forest tree
|
genetics
|
Single-nuclei RNA-sequencing of plant tissues
|
genomics
|
ISA API: An open platform for interoperable life science experimental metadata
|
bioinformatics
|
Set-Min sketch: a probabilistic map for power-law distributions with application to k-mer annotation
|
bioinformatics
|
Melt into the groupElectrophysiological Evidence of Gestalt Perception of Human Dyad
|
neuroscience
|
Fast Alignment-Free Similarity Estimation By Tensor Sketching
|
bioinformatics
|
Sensitivity to Immune Checkpoint Blockade and Progression-Free Survival is associated with baseline CD8+ T cell clone size and cytotoxicity
|
immunology
|
Gene Expression Meta-Analysis Reveals Interferon-induced Genes
|
immunology
|
Evolution of two-component quorum sensing systems
|
evolutionary biology
|
A domestic plant differs from its wild relative along multiple axes of within-plant trait variability and diversity
|
evolutionary biology
|
DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks
|
genomics
|
The discriminatory power of the T cell receptor
|
immunology
|
Transmission of SARS-CoV-2 from humans to animals and potential host adaptation
|
genomics
|
An ancient viral epidemic involving host coronavirus interacting genes more than 20,000 years ago in East Asia
|
evolutionary biology
|
Distinct and Common Neural Coding of Semantic and Non-semantic Control Demands
|
neuroscience
|
Revisiting the notion of deleterious sweeps
|
evolutionary biology
|
Plant PhysioSpace: a robust tool to compare stress response across plant species
|
plant biology
|
Bridging brain and cognition: A multilayer network analysis of brain structural covariance and general intelligence in a developmental sample of struggling learners
|
neuroscience
|
Role of BMP signaling during early development of the annelid Capitella teleta
|
developmental biology
|
Dynamics of vesicle reshaping and scission under osmotic shocks
|
biophysics
|
N2O-respiring bacteria in biogas digestates for reduced agricultural emissions
|
microbiology
|
Population genetics of transposable element load: a mechanistic account of observed overdispersion
|
genomics
|
Celda: A Bayesian model to perform co-clustering of genes into modules and cells into subpopulations using single-cell RNA-seq data
|
bioinformatics
|
Tysserand - Fast and accurate reconstruction of spatial networks from bioimages
|
bioinformatics
|
The gut bacteria of an invasive amphibian respond to the dual challenges of range-expansion and parasite attack
|
microbiology
|
Comprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data
|
bioinformatics
|
Perphenazine-macrocycle conjugates rapidly sequester the Aβ42 monomer and inhibit amyloid formation
|
biophysics
|
Community Detection in a Weighted Directed Hypergraph Representation of Cell-to-cell Communication Networks
|
systems biology
|
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
|
immunology
|
Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck
|
microbiology
|
Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2
|
microbiology
|
HIV-induced membraneless organelles orchestrate post-nuclear entry steps.
|
microbiology
|
Reproductive compensation and embryo screening drive the evolution of polyembryony
|
evolutionary biology
|
Rapidly self-sterilizing PPE capable of 99.9% SARS-CoV-2 deactivation in 30 seconds
|
immunology
|
An Integrated Workflow for Enhanced Taxonomic and Functional Coverage of the Mouse Faecal Metaproteome
|
microbiology
|
UniBind: maps of high-confidence direct TF-DNA interactions across nine species
|
genomics
|
Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques
|
immunology
|
Robustness of phylogenetic inference to model misspecification caused by pairwise epistasis
|
evolutionary biology
|
A large panel of chicken cells are invaded in vivo by Salmonella Typhimurium even when depleted of all known invasion factors
|
microbiology
|
High content Image Analysis to study phenotypic heterogeneity in endothelial cell monolayers
|
cell biology
|
USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma
|
cancer biology
|
New Measures of Visual Scanning Efficiency and Cognitive Effort
|
neuroscience
|
Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK biobank
|
genetics
|
Fully Convolutional Networks for pathophysiological Intracranial Pressure waveform classification
|
physiology
|
PseudotimeDE: inference of differential gene expression along cell pseudotime with well-calibrated p-values from single-cell RNA sequencing data
|
bioinformatics
|
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