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A gain and dynamic range independent index to quantify spillover spread to aid panel design in flow cytometry
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immunology
|
The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
|
evolutionary biology
|
Population differentiation and structural variation in the genome of Manduca sexta across the United States
|
evolutionary biology
|
The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
|
cancer biology
|
Control of neurogenic competence in mammalian hypothalamic tanycytes.
|
neuroscience
|
ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1
|
physiology
|
Learning to live with Dale's principle: ANNs with separate excitatory and inhibitory units
|
neuroscience
|
New Insights from Old Data: Multimodal Classification of Schizophrenia using Automated Deep Learning Configurations
|
neuroscience
|
A global indicator of utilised wildlife populations: regional trends and the impact of management
|
ecology
|
Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus
|
microbiology
|
The Mitochondrial Permeability Transition Pore Activates the Mitochondrial Unfolded Protein Response and Promotes Aging
|
cell biology
|
Reciprocal lateral hypothalamic and raphe GABAergic projections promote wakefulness
|
neuroscience
|
Extensive and accurate benchmarking of DIA acquisition methods and software tools using a complex proteomic standard
|
bioinformatics
|
IonQuant enables accurate and sensitive label-free quantification with FDR-controlled match-between-runs
|
bioinformatics
|
Disrupted visual cortical plasticity in early neurodegeneration
|
neuroscience
|
Synergistic Coding of Carbon Dioxide and a Human Sweat Odorant in the Mosquito Brain
|
neuroscience
|
The evolution of latitudinal ranges in reef-associated fishes: heritability, limits, and inverse Rapoport's rule
|
evolutionary biology
|
Human-in-the-Loop Weight Compensation in Upper Limb Wearable Robots Towards Total Muscles Effort Minimization
|
bioengineering
|
E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer
|
cancer biology
|
Strong and localized coupling controlsdimensionality of neural activity across brainareas
|
neuroscience
|
A genetically encoded, pH-sensitive mTFP1 biosensor for probing lysosomal pH
|
cell biology
|
Condensin extrudes DNA loops in steps up to hundreds of base pairs that are generated by ATP binding events
|
biophysics
|
Peeling Back the Layers: Complex Dynamics Shaping the Evolution of the Ledebouriinae (Scilloideae, Asparagaceae)
|
evolutionary biology
|
Copy number-aware deconvolution of tumor-normal DNA methylation profiles
|
genomics
|
A region-based method for causal mediation analysis of DNA methylation data
|
genomics
|
Towards a Better Understanding of Reverse-Complement Equivariance for Deep Learning Models in Regulatory Genomics
|
bioinformatics
|
Cross-species analysis between the maize smut fungi Ustilago maydis and Sporisorium reilianum highlights the role of transcriptional plasticity of effector orthologs for virulence and disease
|
plant biology
|
Temporal pattern and synergy influence activity of ERK signaling pathways during L-LTP induction
|
neuroscience
|
Cave Thiovulaceae differ metabolically and genomically from marine species
|
microbiology
|
Developmental regulation of mitotic chromosome formation revealed by condensin reporter mice
|
cell biology
|
Spatial structure impacts adaptive therapy by shaping intra-tumoral competition
|
cancer biology
|
Osteosarcoma tumors maintain intra-tumoral heterogeneity, even while adapting to environmental pressures that drive clonal selection
|
cancer biology
|
The Correlation Of Substitution Effects Across Populations And Generations In The Presence Of Non-Additive Functional Gene Action
|
genetics
|
Evolution of Antibody Immunity to SARS-CoV-2
|
immunology
|
SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice
|
immunology
|
The translational landscape of SARS-CoV-2 and infected cells
|
microbiology
|
Estimating latent positions in social and biological networks using Graph Neural Networks in R with GCN4R
|
bioinformatics
|
Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
|
cell biology
|
Exploring the relationship between functional structure and ecosystem multifunctionality requires intraspecific trait variability
|
ecology
|
Fin sweep angle does not determine flapping propulsive performance
|
bioengineering
|
Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences
|
bioinformatics
|
Molecular physiology of pumiliotoxin sequestration in a poison frog
|
physiology
|
Conjunctive spatial and idiothetic codes are topographically organized in the GABAergic cells of the lateral septum
|
neuroscience
|
Intracellular sterol sensing controls intestinal B cell differentiation
|
immunology
|
Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List
|
ecology
|
Computational identification of splicing phenotypes from single cell transcriptomic experiments
|
bioinformatics
|
The post-acute phase of SARS-CoV-2 infection in two macaques species is associated with signs of ongoing virus replication and pathology in pulmonary and extrapulmonary tissues
|
microbiology
|
Cytokinin inhibits fungal development and virulence by targeting cellular trafficking
|
microbiology
|
Scaling up biodiversity ecosystem functioning relationships: the role of environmental heterogeneity in space and time
|
ecology
|
Age-related degradation of optic radiation white matter predicts visual, but not verbal executive functions
|
neuroscience
|
Embedding optimization reveals long-lasting history dependence in neural spiking activity
|
neuroscience
|
A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
|
neuroscience
|
Deep generative selection models of T and B cell receptor repertoires with soNNia
|
immunology
|
Transcription and splicing dynamics during early Drosophila development
|
molecular biology
|
Temporal and trophic partitioning promote coexistence between mesocarnivores in a Mediterranean landscape
|
ecology
|
Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
|
biophysics
|
Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide
|
neuroscience
|
Identification of blood autosomal cis-expression quantitative trait methylation (cis-eQTMs) in children
|
genomics
|
Spatially resolved transcriptomics reveals the architecture of the tumor/microenvironment interface
|
cancer biology
|
Memory shapes microbial populations
|
microbiology
|
The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal cord injury in male mice
|
neuroscience
|
Aryl hydrocarbon receptor and TGF-β inducible early gene mediate a transcriptional axis modulating immune homeostasis in mosquitoes
|
immunology
|
Viscophobic turning dictates microalgae transport in viscosity gradients
|
biophysics
|
The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.
|
microbiology
|
Working Memory Capacities Neurally Dissociate: Evidence from Acute Stroke
|
neuroscience
|
Do congruent lip movements facilitate speech processing in a dynamic audiovisual multi-talker scenario? An ERP study with older and younger adults
|
neuroscience
|
Sexual selection drives maladaptive learning under climate warming
|
evolutionary biology
|
Exosome-Mediated mRNA Delivery For SARS-CoV-2 Vaccination
|
immunology
|
Utility of polygenic embryo screening for disease depends on the selection strategy
|
genetics
|
Population receptive field shapes in early visual cortex are nearly circular
|
neuroscience
|
Expectancy-based rhythmic entrainment as continuous Bayesian inference
|
neuroscience
|
Conserved visual capacity of rats under red light
|
neuroscience
|
Cortical feedback and gating in odor discrimination and generalization
|
neuroscience
|
Modelling the neural code in large populations of correlated neurons
|
neuroscience
|
Interspecies variation of larval locomotion kinematics in the genus Drosophila and its relation to habitat temperature
|
neuroscience
|
Decomposing the role of alpha oscillations during brain maturation
|
neuroscience
|
Insula cortex gates the interplay of action observation and preparation for controlled imitation
|
neuroscience
|
Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii
|
genetics
|
Dorsomedial prefrontal neural ensembles reflect changes in task utility
|
neuroscience
|
Auditory Stimulus-response Modeling with a Match-Mismatch Task
|
neuroscience
|
Age-dependent contribution of domain-general networks to semantic cognition
|
neuroscience
|
Rhinovirus reduces the severity of subsequent respiratory viral infections by interferon-dependent and -independent mechanisms
|
microbiology
|
The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.
|
microbiology
|
Single gene targeted nanopore sequencing enables simultaneous identification and antimicrobial resistance detection of sexually transmitted infections
|
microbiology
|
Predatory selection of mucoid, antibiotic resistant Pseudomonas putida phenotype by myxobacterium Cystobacter ferrugineus
|
microbiology
|
The spatial-temporal dynamics of respiratory syncytial virus infections across the east-west coasts of Australia during 2016-17
|
microbiology
|
Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design
|
bioinformatics
|
A Cell Atlas of Microbe-Responsive Processes in the Zebrafish Intestine
|
developmental biology
|
Identifying latent behavioral states in animal movement with M4, a non-parametric Bayesian method
|
ecology
|
Cortical representation of touch in silico
|
neuroscience
|
Cognitive insights from evolutionarily new brain structures in prefrontal cortex
|
neuroscience
|
The stringent factor Rel from Mycobacterium abscessus regulates metabolism and works as a (p)ppGpp hydrolase
|
microbiology
|
Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
|
microbiology
|
Direct regulation of cell cycle regulatory gene expression by NtrX to promote Sinorhizobium meliloti cell division
|
molecular biology
|
Ex vivo osteochondral test system with control over cartilage defect depth - a pilot study to investigate the effect of oxygen tension and chondrocyte-based treatments in chondral and full thickness defects in an organ model
|
cell biology
|
Orthogonal CRISPR-Cas tools for genome editing, inhibition, and CRISPR recording in zebrafish embryos.
|
genetics
|
Designer Scaffolds for Bioengineered Tissue Interfaces
|
biophysics
|
K+ efflux through postsynaptic NMDA receptors suppresses local astrocytic glutamate uptake
|
neuroscience
|
Time-course in attractiveness of pheromone lure on the smaller tea tortrix moth: A generalized additive mixed model approach
|
ecology
|
Bioactivity assessment of natural compounds using machine learning models based on drug target similarity
|
bioinformatics
|
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