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Deep Neural Network Models of Object Recognition Exhibit Human-like Limitations When Performing Visual Search Tasks
neuroscience
BrainGENIE: The Brain Gene Expression and Network Imputation Engine
bioinformatics
ChronoRoot: High-throughput phenotyping by deep segmentation networks reveals novel temporal parameters of plant root system architecture
plant biology
Spatiotemporal organization of movement-invariant and movement-specific signaling in the output layer of motor cortex
neuroscience
Integrity of the short arm of nuclear pore Y-complex is required for mouse embryonic stem cell growth and differentiation
cell biology
Single-cell RNA-seq analysis of human coronary arteries using an enhanced workflow reveals SMC transitions and candidate drug targets
genomics
Exact and WKB-approximate distributions in a gene expression model with feedback in burst frequency, burst size, and protein stability
systems biology
AKAP350 regulates LFA-1 organization during NK cytolytic response
cell biology
M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity
genomics
Binding Mode of SARS-CoV2 Fusion Peptide to Human Cellular Membrane
biophysics
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
cell biology
Learning and motor-impulse control in crows and domestic chickens
animal behavior and cognition
ASTER: A Method to Predict Clinically Actionable Synthetic Lethal Interactions
bioinformatics
SplineDist: Automated Cell Segmentation with Spline Curves
bioinformatics
Exploring the role of life history traits and introduction effort in understanding invasion success in mammals: A case study of Barbary ground squirrels
ecology
simplifyEnrichment: an R/Bioconductor package for Clustering and Visualizing Functional Enrichment Results
bioinformatics
Counterfactual Hypothesis Testing of Tumor Microenvironment Scenarios Through Semantic Image Synthesis
cancer biology
Genetic diversity and population structure of razor clam Sinonovacula constricta in Ariake Bay, Japan, revealed using RAD-Seq SNP markers.
zoology
High-throughput fluorescent assay for inhibitor screening of proteases from RNA viruses
biochemistry
Species level resolution of female bladder microbiota from 16S rRNA amplicon sequencing
bioinformatics
Resilience in a Natural Model of Metabolic Dysfunction Through Changes in Longevity and Ageing-Related Metabolites
systems biology
Kinetic isotope tracing of glycerol and de novo proteogenic amino acids in Human Lung Carcinoma cells using glucose
biochemistry
Design principles of acidic transcriptional activation domains
systems biology
Genetically-Modified Macrophages Accelerate Myelin Repair
neuroscience
COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms
systems biology
Phosphorylation triggers presynaptic phase separation of Liprin-α3 to control active zone structure
neuroscience
A genome-wide CRISPR/Cas9 knock-out screen identifies the DEAD box RNA helicase DDX42 as a broad antiviral inhibitor
microbiology
Waffle Method: A general and flexible approach for FIB-milling small and anisotropically oriented samples
microbiology
The evolution of two distinct strategies of moth flight
physiology
Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction
systems biology
Markov Abstractions of Electrochemical Reaction-Diffusion in Synaptic Transmission for Neuromorphic Computing
neuroscience
Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice
immunology
Microtissue geometry and cell-generated forces drive patterning of liver progenitor cell differentiation in 3D
bioengineering
Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans
cell biology
Live-dead assay on unlabeled cells using phase imaging with computational specificity
bioengineering
Phosphorothioate Substitutions in RNA Structure Studied by Molecular Dynamics Simulations, QM/MM Calculations and NMR Experiments
biophysics
Predicting modular functions and neural coding of behavior from a synaptic wiring diagram
neuroscience
Inhibition of USP4 attenuates epithelial-mesenchymal transition of renal tubular epithelial cells by TβRI
molecular biology
The effect of activity, energy use, and species identity on environmental DNA shedding of freshwater fish
ecology
Dynamical consequences of regional heterogeneity in the brains transcriptional landscape
neuroscience
Magnetoencephalographic Signatures of Conscious Processing Before Birth
neuroscience
Characterization of spatial dynamics of fMRI data in white matter using diffusion-informed white matter harmonics
neuroscience
Propofol Anesthesia Concentration Rather Than Abrupt Behavioral Unresponsiveness Linearly Degrades Responses in the Rat Primary Auditory Cortex
neuroscience
Absolute measurement of cellular activities using photochromic single-fluorophore biosensors
biophysics
Engineering Gac/Rsm signaling cascade for optogenetic induction of pathogenicity switch in Pseudomonas aeruginosa
synthetic biology
Towards end-to-end disease prediction from raw metagenomic data
genomics
Low nitrogen availability inhibits the phosphorus starvation response in maize (Zea mays ssp. mays L.)
plant biology
Dynamic influences on static measures of metacognition
neuroscience
A phylogenomic perspective on gene tree conflict and character evolution in Caprifoliaceae using target enrichment data, with Zabelioideae recognized as a new subfamily
evolutionary biology
BIO-LGCA: a cellular automaton modelling class for analysing collective cell migration
bioinformatics
The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice
physiology
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates inflammation and transcriptional dysregulation in Huntington's disease
neuroscience
Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates
cell biology
A Library Of Induced Pluripotent Stem Cells From Clinically Well-Characterized, Diverse Healthy Human Individuals
cell biology
Multiple Mechanisms Underlie State-Independent Inhibitory Effects of Norfluoxetine on TREK-2 K2P Channels
biophysics
Dopamine D1 and D4 receptors contribute to light adaptation in ON-sustained retinal ganglion cells
neuroscience
Early invasion of uropathogenic Escherichia coli into the bladder wall by solitary bacteria that are protected from antibiotics and neutrophil swarms in an organoid model
microbiology
Leveraging big data for classification of children who stutter from fluent peers
neuroscience
Forward variable selection improves the power of random forest for high- dimensional microbiome data
bioinformatics
Visual neuroscience methods for marmosets: efficient receptive field mapping and head-free eye tracking
neuroscience
SurfStamp: 3D Printer Compatible Molecular Surface Representation
bioinformatics
Impact of germline and somatic cell cycle checkpoint kinase mutations on breast cancer presentation and prognosis.
bioinformatics
Combined fluorescence, optical diffraction tomography and Brillouin microscopy
biophysics
Evolutionary rescue in one dimensional stepping stone models
evolutionary biology
Investigating spatiotemporal variation in the diet of Westland Petrel through metabarcoding, a non-invasive technique
ecology
Determinants of different facets of beta diversity in Mediterranean marine amphipods
ecology
Are irrigated urban trees more sensitive to light and temperature than water?
ecology
Increasing Grain Yield in Bread Wheat by Selection for High Spike Fertility Index
plant biology
Value Shapes Abstraction During Learning
neuroscience
Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression
cancer biology
Acetylation of conserved lysines fine-tune mitochondrial malate dehydrogenase activity in land plants
plant biology
Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools
cell biology
Investigating epithelial-mesenchymal heterogeneity of tumors and circulating tumor cells with transcriptomic analysis and biophysical modeling
cancer biology
Open Science Discovery of Oral Non-Covalent SARS-CoV-2 Main Protease Inhibitor Therapeutics
biochemistry
Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses OC43 and 229E
evolutionary biology
Sea anemone genomes reveal ancestral metazoan chromosomal macrosynteny
genomics
Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen Receptors can be Fine-Tuned through Hinge Truncation
immunology
Were Neoarchean atmospheric methane hazes and early Paleoproterozoic glaciations driven by the rise of oxygen in surface environments?
systems biology
Development of antibacterial compounds that block evolutionary pathways to resistance
biophysics
Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids
developmental biology
A novel cost framework reveals evidence for competitive selection in the evolution of complex traits during plant domestication
evolutionary biology
Rhythmic modulation of visual perception by continuous rhythmic auditory stimulation
neuroscience
Neuroplasticity associated with changes in conversational turn-taking following a family-based intervention
neuroscience
Phylogenomics reveals that Asaia symbionts from insects underwent convergent genome reduction, preserving an insecticide-degrading gene
microbiology
Leapfrog dynamics in phage-bacteria coevolution revealed by joint analysis of cross-infection phenotypes and whole genome sequencing
evolutionary biology
Catestatin induces glycogenesis by stimulating phosphoinositide 3-kinase-AKT pathway
physiology
A eukaryote-wide perspective on the diversity and evolution of the ARF GTPase protein family
evolutionary biology
The genetic and ecological landscape of plasmids in the human gut
bioinformatics
Natural isotope correction improves analysis of protein modification dynamics
bioinformatics
An insight into SARS-CoV-2 Membrane protein interaction with Spike, Envelope, and Nucleocapsid proteins
bioinformatics
A model for pH coupling of the SARS-CoV-2 spike protein open/closed equilibrium.
bioinformatics
Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic disease
immunology
A non-olfactory shark adenosine receptor activates CFTR with unique pharmacology and structural features
cell biology
Investigating age- and sex-specific effects of socialization on voluntary ethanol administration using a novel vapor paradigm
neuroscience
Structural and functional plasticity in the dorsolateral geniculate nucleus of mice following bilateral enucleation
neuroscience
Preserved sensory processing but hampered conflict detection when stimulus input is task-irrelevant
neuroscience
A biophysical limit for quorum sensing in biofilms
biophysics
Conditional distribution modeling as an alternative method for covariates simulation: comparison with joint multivariate normal and bootstrap techniques
pharmacology and toxicology
A plausible mechanism for longitudinal lock-in of cortical microtubule array after light-induced reorientation
plant biology
Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies
neuroscience