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A generalised mechano-kinetic model for use in multiscale simulation protocols.
biophysics
High-dimensional association detection in large scale genomic data
bioinformatics
Everything you wanted to know about Mayaro virus but were afraid to ask: Characterization and lifecycle of Mayaro virus in vertebrate and invertebrate cellular backgrounds
microbiology
Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni
pharmacology and toxicology
Optimizing interneuron circuits for compartment-specific feedback inhibition
neuroscience
Substrate traits govern the assembly of microbial community engaged in metabolic division of labor
microbiology
A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
systems biology
The ChiS-family DNA-binding domain contains a cryptic helix-turn-helix variant
microbiology
Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 variants of concern by HMOX-1 upregulation in human cells
microbiology
Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility.
developmental biology
Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes
molecular biology
ABC-finder: A containerized web server for the identification and topology prediction of ABC proteins
bioinformatics
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
microbiology
Genetic and pharmacological manipulations of glyoxalase 1 mediate ethanol withdrawal seizure susceptibility in mice
neuroscience
Complex trait-environment relationships underlie the structure of Wisconsin forest plant communities
ecology
Human methylome variation across Infinium 450K data on the Gene Expression Omnibus
genomics
Universal annotation of the human genome through integration of over a thousand epigenomic datasets
bioinformatics
Topology-based Sparsification of Graph Annotations
bioinformatics
The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the discovery, prediction, and exploration of mutational signatures
bioinformatics
Raman microscopy-based quantification of the physical properties of intracellular lipids
biophysics
Temporal dynamics of implicit memory underlying serial dependence
neuroscience
Multisensory integration-attention trade-off in cochlear-implanted deaf individuals
neuroscience
Selective vulnerability of supragranular layer neurons in schizophrenia
neuroscience
Cis regulation within a cluster of viral microRNAs
molecular biology
Ultrafast pore-loop dynamics in a AAA+ machine point to a Brownian-ratchet mechanism for protein translocation
biophysics
Long-term stability of avalanche scaling and integrative network organization in prefrontal and premotor cortex
neuroscience
The road to sorghum domestication: evidence from nucleotide diversity and gene expression patterns
evolutionary biology
The loops of the N-SH2 binding cleft do not serve as allosteric switch in SHP2 activation
biophysics
Time-Encoding Migrates from Prefrontal Cortex to Dorsal Striatum During Learning of a Self-Timed Response Duration Task
neuroscience
U-Net Model for Brain Extraction: Trained on Humans for Transfer to Non-human Primates
neuroscience
Inferring parameters of cancer evolution from sequencing and clinical data
cancer biology
Quantitative dSTORM super-resolution microscopy localizes Aurora kinase A/AURKA in the mitochondrial matrix
cell biology
Repeated blast mild traumatic brain injury and oxycodone self-administration produce interactive effects on neuroimaging outcomes
neuroscience
Spatial structure of natural boxwood and the invasive box tree moth can promote coexistence
ecology
Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-infused Mice
pathology
Large-Scale Analysis of Circulating Amino Acids and Gene Expression in Relation to Abdominal Obesity
physiology
Deciphering the genetic basis of wheat seminal root anatomy uncovers ancestral axial conductance alleles
plant biology
Divergence in a stress-associated gene regulatory network underlies differential growth control in the Brassicaceae family
plant biology
Multiple routes of functional diversification of the plant BAHD acyltransferase family revealed by comparative biochemical and genomic analyses
plant biology
Recurrent circuit based neural population codes for stimulus representation and inference
neuroscience
Passive visual stimulation induces fatigue or improvement depending on cognitive load
neuroscience
Enhanced olfactory memory performance in trap-design Y-mazes allows the study of novel memory phenotypes in Drosophila
neuroscience
A putative erm gene is present in ΔermB Clostridioides difficile isolates showing high levels of resistance to clindamycin
microbiology
Paracrine regulation of neural crest EMT by placodal MMP28
developmental biology
An investigation of MHC-dependent sexual selection in a free-living population of sheep
evolutionary biology
Phylogenomics of a new fungal phylum reveals multiple waves of reductive evolution across Holomycota
evolutionary biology
Peroxisome import stress impairs ribosome biogenesis and induces integrative stress response through eIF2α phosphorylation
genomics
Intranasal oxytocin drives coordinated social approach
animal behavior and cognition
Deep neural network models reveal interplay of peripheral coding and stimulus statistics in pitch perception
animal behavior and cognition
Multiple latent clustering model for the inference of RNA life-cycle kinetic rates from sequencing data
bioinformatics
Efficient and precise single-cell reference atlas mapping with Symphony
bioinformatics
AMPGAN v2: Machine Learning Guided Discovery of Anti-Microbial Peptides
biophysics
A causal analysis of the effect of age and sex differences on brain atrophy in the elderly brain
neuroscience
Mapping the contents of consciousness during musical imagery
neuroscience
Unilateral acoustic degradation delays attentional separation of competing speech
neuroscience
Frontoparietal pattern similarity analyses of cognitive control in monozygotic twins
neuroscience
Null effects of levodopa on reward- and error-based motor adaptation, savings, and anterograde interference
neuroscience
Stress-sensitive inference of task controllability
neuroscience
Intra-individual variability in task performance after cognitive training is associated with long-term outcomes in children
neuroscience
A Cre-dependent CRISPR/dCas9 system for gene expression regulation in neurons
neuroscience
Ribonucleotide reductase, a novel target for gonorrhea
microbiology
Molecular signatures of resource competition: clonal interference favors ecological diversification and can lead to incipient speciation
evolutionary biology
Genomic Resources of Broomcorn Millet: Demonstration and Application of a High-throughput BAC Mapping Pipeline
genomics
Cerebral biodistribution and real-time particle tracking in vivo of ultrabright fluorescent PLGA nano-carriers
bioengineering
TimeCycle: Topology Inspired MEthod for the Detection of Cycling Transcripts in Circadian Time-Series Data
bioinformatics
scDesign2: a transparent simulator that generates high-fidelity single-cell gene expression count data with gene correlations captured
bioinformatics
Low intrinsic efficacy alone cannot explain the improved side effect profiles of new opioid agonists
pharmacology and toxicology
Optimal density of biological cells
biophysics
Basal neural stem cells drive postnatal neurogenesis whereas apical stem cells act as proliferation gatekeepers by regulating notch activation in the postnatal ventricular-subventricular zone
cell biology
Chromosomal neighbourhoods allow identification of organ specific changes in gene expression
bioinformatics
Temporal dynamics of animacy categorization in the brain of patients with mild cognitive impairment
neuroscience
Structural dynamics of the functional nonameric Type III translocase export gate
molecular biology
Genetically controlled mtDNA editing prevents ROS damage by arresting oxidative phosphorylation
cell biology
Host-associated rhizobia fitness: Dependence on nitrogen, density, community complexity, and legume genotype
ecology
Impacts of water quality on Acropora coral settlement: The relative importance of substrate quality and light
ecology
Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of obesity
genomics
Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
genomics
Clipper: p-value-free FDR control on high-throughput data from two conditions
bioinformatics
Coarse-grained model of mitochondrial metabolism enables subcellular flux inference from fluorescence lifetime imaging of NADH
biophysics
Convergent consequences of parthenogenesis on stick insect genomes
evolutionary biology
Crosstalk between repair pathways elicits Double-Strand Breaks in alkylated DNA: implications for the action of temozolomide
biochemistry
CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
biochemistry
Resources allocation explains the differential roles of RBS and promoter strengths in cell mass distribution and optimal protein expression productivity
synthetic biology
A history of previous childbirths is linked to women's white matter brain age in midlife and older age
neuroscience
Dynamic integration and segregation of amygdala subregional functional circuits linking to physiological arousal
neuroscience
Novel Cluster AZ Arthrobacter phages Powerpuff, Lego, and YesChef exhibit close functional relationships with Microbacterium phages
microbiology
Spatial arrangement and biofertilizers enhance the performance of legume-millet intercropping system in rainfed areas of southern India
ecology
Uncovering transposable element variants and their potential adaptive impact in urban populations of the malaria vector Anopheles coluzzii
genomics
My voice therefore I spoke: sense of agency over speech enhanced in hearing self-voice
neuroscience
Inferring a spatial code of cell-cell interactions across a whole animal body
bioinformatics
Identification of new marker genes from plant single-cell RNA-seq data using interpretable machine learning methods
bioinformatics
ER bodies are induced by Pseudomonas syringae and negatively regulate immunity
plant biology
Mosaic vaccination: how distributing different vaccines across a population could improve epidemic control
evolutionary biology
Modulation of implanted aortic scaffold- involvement of ECM and immune proteins
bioengineering
A solution to temporal credit assignment using cell-type-specific modulatory signals
neuroscience
A representational similarity analysis of cognitive control during color-word Stroop
neuroscience
Low prevalence of natural Wolbachia in major malarial vectors Anopheles culicifacies s.l., and Anopheles stephensi: a first report
microbiology
EMBEDR: Distinguishing Signal from Noise in Single-Cell Omics Data
bioinformatics
Antagonistic modules, SIB1 and LSD1, regulate photosynthesis-associated nuclear genes via GOLDEN2-LIKE transcription factors in Arabidopsis
plant biology
Diurnal transcript profiling of the diatom Seminavisrobusta reveals adaptations to a benthic lifestyle
systems biology