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Vocalization categorization behavior explained by a feature-based auditory categorization model
neuroscience
Introducing RELAX (the Reduction of Electroencephalographic Artifacts): A fully automated pre-processing pipeline for cleaning EEG data - Part 1: Algorithm and Application to Oscillations
neuroscience
Methionine uptake via SLC43A2 transporter is essential for regulatory T lymphocyte survival
immunology
Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability
cell biology
Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury
cell biology
Interconnection between molecular regulators in LMNA related muscular dystrophy
cell biology
Inter-microscope comparability of dental microwear texture data obtained from obtained from different optical profilometers.
ecology
MOSAIC: A Unified Trait Database to Complement Structured Population Models
ecology
Origin and persistence of polymorphism in loci targeted by disassortative preference: a general model
evolutionary biology
Putting life history theory to the test - the estimation of reproductive values from field data
evolutionary biology
Accelerating Minimap2 for accurate long read alignment on GPUs
genomics
Fear of the new? Geckos hesitate to attack novel prey, feed near objects and enter a novel space
animal behavior and cognition
URB597 induces aggression in adult Lister Hooded rats
neuroscience
The Vaccinia virus chondroitin sulfate binding protein drives host membrane curvature to facilitate fusion
microbiology
Voltage-Sensing Phosphatase (VSP) Regulates Endocytosis-Dependent Nutrient Absorption in Chordate Enterocytes
cell biology
NAK associated protein 1 is required to activate Tank binding kinase 1 to regulate mitosis
cell biology
Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis
cell biology
Coevolution of the Tlx homeobox gene with medusa development (Cnidaria: Medusozoa)
evolutionary biology
Remodeled Connexin 43 hemichannels alter cardiac excitability and promote arrhythmias
physiology
Cohesin is required for meiotic spindle assembly independent of its role in cohesion in C. elegans
cell biology
Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer's disease
neuroscience
Rickettsia typhi peptidoglycan mapping with data-dependent tandem mass spectrometry
microbiology
CRISPR-Cas12a targeting of ssDNA plays no detectable role in immunity
microbiology
Development of a Novel Bruton's Tyrosine Kinase Inhibitor that exerts Anti-Cancer Activities Potentiates Response of Chemotherapeutic Agents In Multiple Myeloma Stem Cell-Like Cells
molecular biology
A novel Vps34 complex constrains loop extrusion-mediated P-H2A spreading
molecular biology
Cryo-EM reconstructions of LiCl core particles show strong similarities between disassembly and assembly of the ribosomal 50S subunit
molecular biology
The mitochondrial genome segregation system of T. brucei: Single p197 molecules connect the basal body with the outer membrane
cell biology
DNA Double Strand Breaks cause chromosome loss through sister chromatid tethering in human embryos
developmental biology
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases
genomics
Structural variation turnovers and defective genomes: key drivers for the in vitro evolution of the large double-stranded DNA koi herpesvirus (KHV)
genomics
Structural basis for APE1 processing DNA damage in the nucleosome
biochemistry
Altered DNA repair pathway engagement by engineered CRISPR-Cas9 nucleases
bioengineering
Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat generated by CRISPR/Cas9
immunology
Genetic diversity and characterization of circular replication(Rep)-encoding single-stranded (CRESS) DNA viruses
microbiology
The characterization of multiple novel paramyxovirus species highlights the diverse nature of the subfamily Orthoparamyxovirinae
microbiology
IPMK modulates insulin-mediated suppression of hepatic glucose production
molecular biology
Structure and mechanism of a mitochondrial AAA+ disaggregase CLBP
molecular biology
Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis
molecular biology
S. pombe Rtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1
genetics
AlphaFold Models of Small Proteins Rival the Accuracy of Solution NMR Structures
biochemistry
Alterations to the broad-spectrum formin inhibitor SMIFH2 improve potency
biochemistry
Comparison of sampling methods for small oxbow wetland fish communities
ecology
Towards a bionic IoT: environmental monitoring using smartphone interrogated plant sensors
plant biology
Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells
cancer biology
On optimal temozolomide scheduling for slowly growing gliomas
cancer biology
Actin-dependent recruitment of Ago2 to the zonula adherens
cell biology
Lamin A/C mediated invaginations in the nuclear surface allow the nucleus to pass unimpeded through a dense array of fiber-like obstacles
cell biology
Constitutive 5-HT2C receptor knock-out facilitates fear extinction through altered activity of a dorsal raphe-bed nucleus of the stria terminalis pathway
neuroscience
Type I interferons govern Zika virus resistance of human macrophages and microglia
cell biology
Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair
cell biology
Extracellular prostaglandins E1 and E2 and inflammatory cytokines are regulated by the senescence program in potentially premalignant oral keratinocytes
cell biology
Minimizing cell number fluctuations in self-renewing tissues with a stem cell niche
cell biology
Recombinant annexin A6 promotes membrane repair in a stem cell derived-cardiomyocyte model of dystrophic cardiomyopathy
bioengineering
{Pi}-{Pi} Interactions Stabilize PeptoMicelle-Based Formulations of Pretomanid Derivatives Leading to Promising Therapy Against Tuberculosis in Zebrafish and Mouse Models
bioengineering
Efficacy and safety of a patch containing adipose-derived stem cells for skin wound healing. Results form a comprehensive pre-clinical evaluation program
bioengineering
The chromatin associated Sin3B is a critical regulator of DNA damage repair through the engagement of the Non-Homologous End Joining.
cancer biology
Tailoring CRISPR-Cas Immunity for the Degradation of Antibiotic Resistance Genes
synthetic biology
Large-Scale Circuit Configuration for Flexible Sensory-Motor Decisions
neuroscience
An integrated cell atlas of the human lung in health and disease
cell biology
A chemical molecule promotes Trop2+ biliary duct organoids differentiation into insulin-secreting cells
cell biology
Epithelial monolayer development and tight junction assembly on nanopillar arrays
cell biology
A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development.
developmental biology
Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring
genomics
NudF-boosted strategy to improve the yield of DXS pathway
bioengineering
Stretching of long double-stranded DNA and RNA described by the same model.
biophysics
Longitudinal dynamics of microvascular recovery after acquired cortical injury
neuroscience
Polyploidy and plant-fungus symbiosis: evidence of cytotype-specific microbiomes in the halophyte Salicornia (Amaranthaceae)
ecology
Analysis of the persistence and particle size distributional shift of sperm-derived environmental DNA to monitor Jack Mackerel spawning activity
ecology
GENESPACE: syntenic pan-genome annotations for eukaryotes
genomics
Emergent periodicity in the collective synchronous flashing of fireflies
animal behavior and cognition
Structure and regulation of the Myotonic dystrophy kinase-Related Cdc42-binding Kinase
biochemistry
A Strategy to Quantify Myofibroblast Activation on a Continuous Spectrum
bioengineering
Whole brain network analysis of neural synchrony and information flow during transition from wakefulness to light non-rapid eye movement sleep
bioengineering
PCA outperforms popular hidden variable inference methods for QTL mapping
bioinformatics
Clinical application of tumour in normal contamination assessment from whole genome sequencing
bioinformatics
Dynamic Network Curvature Analysis of RNA-Seq Data in Sarcoma
bioinformatics
Tension Gauge Tethers as tension-dependent lifetime sensors
biophysics
Microscope Alignment Using Real-Time Imaging FCS
biophysics
Thermodynamic stabilization of the von Willebrand Factor A1 domain due to loss-of-function disease-related mutations.
biophysics
Allosteric inhibitors of Zika virus NS2B-NS3 protease targeting protease in super-open conformation
pharmacology and toxicology
Identification and quantification of α- and β-amanitin in wild mushrooms by HPLC-UV-EC and HPLC-DAD-MS detection
pharmacology and toxicology
A WAX INDUCER1/SHINE transcription factor controls cuticular wax in barley
plant biology
Programming bacteria to sense environmental DNA for multiplexed pathogen detection
synthetic biology
Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy
systems biology
Comparative transcriptomics of the Drosophila olfactory subsystems identifies a support cell-expressed Osiris protein required for pheromone sensing
neuroscience
Cognitive penetrability of scene representations based on horizontal image disparities
neuroscience
Neuron-derived Thioredoxin-80: a novel regulator of type-I interferon response in microglia
neuroscience
Choroid plexus tissue perfusion and secretory function in rats measured by non-invasive MRI reveal significant effects of anesthesia
neuroscience
Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes
neuroscience
The lateral intraparietal area preferentially supports stimulus selection in directed tasks compared to undirected free behavior
neuroscience
Ambient RNA analysis reveals misinterpreted and masked cell types in brain single-nuclei datasets
neuroscience
The Musashi proteins are post-transcriptional activators of protein expression and alternative exon splicing in vertebrate photoreceptors
neuroscience
The vigor paradox: saccade velocity during deliberation encodes utility of effortful actions
neuroscience
NLGC: Network Localized Granger Causality with Application to MEG Directional Functional Connectivity Analysis
neuroscience
Innate immune response and distinct metabolomic signatures together drive and shape the SARS-CoV-2-specific T cell response during COVID-19
immunology
Characterization of Morreton Virus (MORV) as a Novel Oncolytic Virotherapy Platform for Liver Cancers
immunology
HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine
immunology
Increased receptor affinity and reduced recognition by specific antibodies contribute to immune escape of SARS-CoV-2 variant Omicron
immunology
A core transcriptional response for biofilm formation by Y. pseudotuberculosis
microbiology
Development of a tractable model system to mimic wood-ageing of beer on a lab scale
microbiology