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Phytochemical-induced mucin accumulation in the gastrointestinal lumen is independent of the microbiota
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microbiology
|
Bartonella taylorii: A model organism for studying Bartonella infection in vitro and in vivo
|
microbiology
|
Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs
|
microbiology
|
Blocking unwanted sequences by target specific high-affinity binding oligonucleotides during transcriptome library preparation
|
molecular biology
|
SELF PRUNING 3C is a flowering repressor that modulates seed germination, root architecture and drought responses
|
molecular biology
|
A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
|
developmental biology
|
Thymus formation in uncharted embryonic territories.
|
developmental biology
|
Continuing decline of the eastern quoll in Tasmania
|
ecology
|
MitoSearch: Construction of fish species composition database with environmental DNA using public databases
|
ecology
|
A chronotype effect: circadian-period variation underlies the local adaptation of photoperiodism in the short-day plant Lemna aequinoctialis.
|
ecology
|
Cross-generational heritability analysis of physiological traits in Porites astreoides across an inshore-offshore gradient in the Lower Florida Keys
|
ecology
|
Niche-based deterministic assembly processes strengthen the effects of β-diversity on metacommunity functioning of marine bacterioplankton
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ecology
|
Focusing the GWAS Lens on days to flower using latent variable phenotypes derived from global multi-environment trials
|
genetics
|
Assembly and phylogeographic analysis of novel Taenia solium mitochondrial genomes reveal further differentiation between and within Asian and African-American genotypes
|
genetics
|
Multi-omics comparison of malignant and normal uveal melanocytes reveals novel molecular features of uveal melanoma.
|
genomics
|
Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells
|
bioengineering
|
Fabrication of Conductive Hollow Microfibers for Encapsulation of Astrocyte Cells
|
bioengineering
|
A deep unsupervised language model for protein design
|
bioinformatics
|
CRISPRcleanR WebApp: an interactive web application for processing genome-wide pooled CRISPR-Cas9 viability screen
|
bioinformatics
|
Ion channel model reduction using manifold boundaries
|
biophysics
|
Prokaryotic genome design is ruled by the mechanical properties and complexity of the DNA sequence
|
biophysics
|
Insight into Polyproline II Helical Bundle Stability and Folding from NMR Spectroscopic Characterization of the Snow Flea Antifreeze Protein Denatured State
|
biophysics
|
Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemo-mechanical properties despite the same myosin heavy chain isoform.
|
biophysics
|
Pan-cancer distribution of cleaved cell-surface Amphiregulin, the target of the GMF-1A3 antibody drug conjugate
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cancer biology
|
Flotillin-2 regulates EGFR activation, degradation, and cancer growth
|
cancer biology
|
Structure and function of diadenylate cyclase DacM from Mycoplasma ovipneumoniae
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pathology
|
Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue.
|
physiology
|
Odors drive feeding through gustatory receptor neurons in Drosophila
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neuroscience
|
BLMM: Parallelised Computing for Big Linear Mixed Models
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neuroscience
|
Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.
|
neuroscience
|
A Trem2*R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques
|
neuroscience
|
Organization of thalamocortical structural covariance and a corresponding 3D atlas of the mouse thalamus
|
neuroscience
|
Neuromodulation of striatal D1 cells shapes BOLD fluctuations in anatomically connected thalamic and cortical regions
|
neuroscience
|
Development of a PET radioligand for α2δ-1 subunit of calcium channels for imaging neuropathic pain
|
neuroscience
|
Electroencephalographic dynamics of rhythmicbreath-based meditation
|
neuroscience
|
Alpha-1-antitrypsin binds to the glucocorticoid receptor with biological significance in macrophages
|
immunology
|
The role of Staphylococcus agnetis and Staphylococcus hyicus in the pathogenesis of buffalo fly skin lesions in cattle
|
microbiology
|
Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence
|
cell biology
|
Automated classification of estrous stage in rodents using deep learning
|
cell biology
|
ID1 and CEBPA Coordinate Epidermal Progenitor Cell Differentiation
|
developmental biology
|
Estimating contemporary migration numbers of adults based on kinship relationships in iteroparous species
|
ecology
|
Effects of disease emergence on invasive grass impacts
|
ecology
|
Analysis of synthetic genetic interactions of non-coding RNAs in Saccharomyces cerevisiae
|
genetics
|
Oxytocin and Emotional Tear in Dogs
|
animal behavior and cognition
|
Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development
|
biochemistry
|
Double NPY motifs at the N-terminus of Sso2 synergistically bind Sec3 to promote membrane fusion
|
biochemistry
|
Generating minimum set of gRNA to cover multiple targets in multiple genomes with MINORg
|
bioinformatics
|
Mechanical stress driven by rigidity sensing governs epithelial stability
|
biophysics
|
Direct measurement of the aerotactic response in a bacterial suspension
|
biophysics
|
Evaluating the "cost of generating force" hypothesis across frequency in human running and hopping
|
physiology
|
Robust high-throughput phenotyping with deep segmentation enabled by a web-based annotator
|
plant biology
|
Characterization of dengue virus 3UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva
|
zoology
|
The role of UBE3A in the autism and epilepsy-related Dup15q syndrome using patient-derived, CRISPR-corrected neurons
|
neuroscience
|
Pan-phylum In Silico Analyses of Nematode Endocannabinoid Signalling Systems Highlight Novel Opportunities for Parasite Drug Target Discovery
|
neuroscience
|
Domain-general and domain-specific functional networks of Broca's area underlying language processing
|
neuroscience
|
The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice
|
neuroscience
|
Influenza A Virus Compromises anti-Streptococcal Innate Immunity
|
immunology
|
IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity
|
immunology
|
Functional entry of Members of Venezuelan Equine Encephalitis Complex into host cells is dependent on clathrin-mediated endocytosis, in a pH-Dependent Manner
|
microbiology
|
Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls
|
molecular biology
|
Alveolar regeneration following viral infection is independent of tuft cells
|
cell biology
|
An easily modifiable conjugative plasmid for studying horizontal gene transfer
|
evolutionary biology
|
Using Local Genetic Correlation Improves Polygenic Score Prediction Across Traits
|
genomics
|
Floating EMG Sensors and Stimulators Wirelessly Powered and Operated by Volume Conduction for Networked Neuroprosthetics
|
bioengineering
|
Improved eukaryotic detection compatible with large-scale automated analysis of metagenomes
|
bioinformatics
|
Accurate in silico confirmation of rare copy number variant calls from exome sequencing data using transfer learning
|
bioinformatics
|
Web-based Histology Reference Atlas for the Freshwater Crustacean Daphnia magna
|
zoology
|
A connectomics-based taxonomy of mammals
|
neuroscience
|
Genetic mapping of APP and amyloid-β biology modulation by trisomy 21
|
neuroscience
|
In vitro susceptibility to beta-lactam antibiotics and viability of Neisseria gonorrhoeae strains producing plasmid-mediated broad- and extended-spectrum beta-lactamases
|
microbiology
|
The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity
|
cell biology
|
Novel pathogen introduction rapidly alters evolved movement strategies, restructuring animal societies
|
ecology
|
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies
|
genetics
|
Observation of a single protein by ultrafast X-ray diffraction
|
biophysics
|
Calcium-induced environmental adaptability of the blood protein vitronectin
|
biophysics
|
Field and experimental data together with computational models reveal how cleaner fish adjust decisions in a biological market
|
animal behavior and cognition
|
Reference genome choice and filtering thresholds jointly influence phylogenomic analyses
|
bioinformatics
|
Blockade of redox second messengers inhibits JAK/STAT and MEK/ERK signaling sensitizing FLT3-mutant acute myeloid leukemia to targeted therapies
|
cancer biology
|
Triosephosphate export from chloroplasts regulates flavonoid biosynthesis and permits high light acclimation through the inactivation of SnRK1
|
plant biology
|
Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain
|
neuroscience
|
Modelling the modulation of cortical Up-Down state switching by astrocytes
|
neuroscience
|
Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
|
neuroscience
|
Placental inflammation leads to abnormal embryonic heart development
|
immunology
|
Prokaryotic phospholipid translocation by ubiquitous PplT domain proteins
|
microbiology
|
Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing
|
genetics
|
Resolving clonal substructure from single cell genomic data using CopyKit
|
genomics
|
Structural and biochemical insights into lipid transport by VPS13 proteins.
|
cell biology
|
Deep learning in human neurons predicts mechanistic subtypes of Parkinson's
|
cell biology
|
The inositol-requiring enzyme 1α/X-box protein 1 (IRE1α/XBP1) pathway of the unfolded protein response is impaired in pediatric cholestatic liver disease explants
|
cell biology
|
Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction
|
biochemistry
|
Oligomer-to-Monomer Transition Underlies the Chaperone Function of AAGAB in AP1/AP2 Assembly
|
biochemistry
|
State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold
|
biophysics
|
Cryo-EM structure of amyloid fibril formed by α-synuclein familial A53E mutation
|
biophysics
|
Loss of tumor suppressor WWOX enhances RAS activity in pancreatic cancer
|
cancer biology
|
The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor
|
cell biology
|
Visualization of mRNA Expression in Pseudomonas aeruginosa Aggregates Reveals Spatial Patterns of Fermentative and Denitrifying Metabolism
|
microbiology
|
IRONMAN interacts with OsHRZ1 and OsHRZ2 to maintain Fe homeostasis
|
molecular biology
|
Accurate detection of structural variation is hard
|
genomics
|
Impact of dominance rank specification in dyadic interaction models
|
animal behavior and cognition
|
Interspecies isobaric labeling-based quantitative proteomics reveals protein changes in the ovary of Aedes aegypti co-infected with ZIKV and Wolbachia
|
biochemistry
|
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