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sstar: A Python package for detecting archaic introgression from population genetic data with S*
genomics
In vivo CRISPR screens reveal SCAF1 and USP15 as novel drivers of pancreatic cancer
cancer biology
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer
cancer biology
Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling
developmental biology
Wnt and BMP signaling enhance melanocyte regeneration and suppress melanoma cell migration
developmental biology
Genome-resolved metaproteomics decodes the microbial and viral contributions to coupled carbon and nitrogen cycling in river sediments
microbiology
Metal Coordinating Inhibitors of Rift Valley Fever virus Replication
microbiology
Synapse-type-specific competitive Hebbian learning forms functional recurrent networks
neuroscience
A robust Reeb graph model of white matter fibers with application to Alzheimer's disease progression
neuroscience
Patterned apoptosis modulates local growth and tissue shape in a fast-growing epithelium
developmental biology
The extinction of threatened species by anthropogenic threats endangers the functional diversity of turtles and crocodiles
ecology
Improved basic cytogenetics challenges holocentricity of butterfly chromosomes
genetics
Assessment of genetic diversity and SNP marker development within peanut germplasm in Taiwan by RAD-seq
genetics
High-frame-rate analysis of knee cartilage deformation by spiral dualMRI and relaxation mapping
bioengineering
cgRNASP: coarse-grained statistical potentials with residue separation for RNA structure evaluation
biophysics
Profiling Mouse Brown and White Adipocytes to Identify Metabolically Relevant Small ORFs and Functional Microproteins
systems biology
Rhythm of relationships in a social fish over the course of a full year in the wild
animal behavior and cognition
Wireless networks of injectable microelectronic stimulators based on rectification of volume conducted high frequency currents
bioengineering
dialogi: Utilising NLP with chemical and disease similarities to drive the identification of Drug-Induced Liver Injury literature
bioinformatics
FPGA Acceleration of GWAS Permutation Testing
bioinformatics
Selective Control of Parasitic Nematodes Using Bioactivated Nematicides
pharmacology and toxicology
A fungal endophyte-generated nucleoside signal regulates host cell death and promotes root colonization
plant biology
BrainQCNet: a Deep Learning attention-based model for multi-scale detection of artifacts in brain structural MRI scans
neuroscience
A novel automated morphological analysis of microglia activation using a deep learning assisted model
neuroscience
Synapse type-specific molecular nanoconfigurations of the presynaptic active zone in the hippocampus identified by systematic nanoscopy
neuroscience
Coherent network oscillations regulate quiescence and behavioral responsiveness in Drosophila
neuroscience
B cells are addicted to immunoglobulin production in the ER
immunology
The AppNL-G-F mouse model of Alzheimer's disease is refractory to regulatory T cell treatment
immunology
The asymmetric ABA response on both sides of root tip is important for tomato root hydrotropism by mediating proton efflux and cell elongation
ecology
Elevated human footprint on islands promotes both introduction and extinction probability of insular reptiles at opposite ends of geographic, evolutionary and ecological continua
ecology
Positive selection of senescence through increased evolvability: ageing is not a by-product of evolution.
evolutionary biology
Black Queen Hypothesis, partial privatization, andquorum sensing evolution
evolutionary biology
A re-emerging arbovirus in livestock in China: Early genomic surveillance and phylogeographic analysis
evolutionary biology
Sulfur-mediated chalcogen versus hydrogen bonds in proteins: a seesaw effect in the conformational space
biochemistry
Human myelin proteolipid protein structure and lipid bilayer stacking
biochemistry
Tetrasulfide Bridge (TTSB) Formation: an Extraordinary Intermediate Structure in the Architecture and Dynamics of the HIV-1s gp120 molecule
biochemistry
A low-power communication scheme for wireless, 1000 channel brain-machine interfaces
bioengineering
OncoPubMiner: A platform for oncology publication mining
bioinformatics
Testing microbiome associations with censored survival outcomes at both the community and individual taxon levels
bioinformatics
AttnPacker: An end-to-end deep learning method for rotamer-free protein side-chain packing
bioinformatics
A method to predict 3D structural ensembles of chromatins from pairwise distances: Applications to Interphase Chromosomes and Structural Variants
biophysics
DeepSCM: an efficient convolutional neural network surrogate model for the screening of therapeutic antibody viscosity
biophysics
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
cancer biology
Human endogenous retrovirus activation contributes to biliary atresia pathogenesis through re-education of resident macrophages
pathology
A Nematode-Selective Potentiator of Organophosphate and Carbamate Agrochemicals
pharmacology and toxicology
Comparing flickering and pulsed chromatic pupil light responses
physiology
Physiological trait networks enhance understanding of crop growth and water use in contrasting environments
plant biology
A comprehensive mechanistic model of adipocyte signaling with layers of confidence
systems biology
A Spatiotemporal Reconstruction of the C. elegans Pharyngeal Cuticle Reveals a Structure Rich in Phase-Separating Proteins
systems biology
Comparative analysis of total alpha-synuclein (αSYN) immunoassays reveals that they do not capture the diversity of modified αSYN proteoforms
neuroscience
Chemogenetic enhancement of cAMP signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation
neuroscience
Neurons in inferior temporal cortex are sensitive to motion trajectory during degraded object recognition
neuroscience
Dimensionality reduction of calcium-imaged neuronal population activity
neuroscience
Implicit sensorimotor adaptation is preserved in Parkinson's Disease
neuroscience
Circuit analysis of the Drosophila brain using connectivity-based neuronal classification reveals organization of key information processing pathways
neuroscience
Antecedent effect models as an exploratory rather than predictive tool to understand the response of plant populations to climate drivers
ecology
Urbanization and green corridors influence reproductive success and pollinators of common milkweed
ecology
Functional universality in slow-growing microbial communities arises from thermodynamic constraints
ecology
Reproductive barriers and genomic hotspots of adaptation during allopatric species divergence
evolutionary biology
A self-adjusting, progressive shock magnitude procedure to investigate resistance to punishment: characterization in male and female rats
animal behavior and cognition
Strength-mass scaling law governs mass distribution inside honey bee swarms
animal behavior and cognition
GRAPE: Genomic Relatedness Detection Pipeline
bioinformatics
Tension anisotropy drives phenotypic transitions of cells via two-way cell-ECM feedback
biophysics
Generative and interpretable machine learning for aptamer design and analysis of in vitro sequence selection
biophysics
Automated patch clamp screening of amiloride and 5-N,N-hexamethyleneamiloride (HMA) analogs identifies 6-iodoamiloride as a potent acid-sensing ion channel inhibitor.
pharmacology and toxicology
Is Melanopsin Activation Affecting Large Field Color Matching Functions?
physiology
Phyllochron duration and changes through rice development shape the vertical leaf size profile
plant biology
Impairments in fear extinction memory and basolateral amygdala plasticity in the TgF344-AD rat model of Alzheimer's disease are distinct from non-pathological aging.
neuroscience
Associations between locus coeruleus MRI contrast and physiological responses to acute stress in younger and older adults
neuroscience
Examination of diurnal variation and sex differences in hippocampal neurophysiology and spatial memory
neuroscience
Sample size requirement for achieving multisite harmonization using structural brain MRI features
neuroscience
E-cigarette vapour from base components propylene glycol and vegetable glycerine inhibits inflammatory response in macrophages and epithelial cells
immunology
A minimal growth medium for Pseudomonas azotoformans associated with insect gut
microbiology
Molecular architecture of the TasA biofilm scaffold in Bacillus subtilis
microbiology
Gram-negative Antimicrobial spectrum of Ulmus pumila
microbiology
Inorganic sulfur fixation via a new homocysteine synthase allows yeast cells to cooperatively compensate for methionine auxotrophy
molecular biology
Diffusional variance-determined stochastic translation efficiency
molecular biology
Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events
molecular biology
Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility
evolutionary biology
Shared and distinct genetic etiologies for different types of clonal hematopoiesis
genetics
A Microengineered Brain-Chip to Model Neuroinflammation in Humans
bioengineering
High axial-resolution optical stimulation of neurons in vivo via two-photon optogenetics with speckle-free beaded-ring pattern
bioengineering
Deep brain stimulation pulse sequences to optimally modulate frequency-specific neural activity
bioengineering
Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit
biophysics
LIPA-driven hydrolysis of cholesteryl arachidonate promotes cancer metastasis via NF-κB
cancer biology
Invasiveness of Cancer Populations in a Two-dimensional Percolation cluster: a Stochastic Mathematical Approach
cancer biology
Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats
pharmacology and toxicology
Culture media, DMSO and efflux affect the antibacterial activity of cisplatin and oxaliplatin
microbiology
Genome-wide analysis of PTR/POT transporters in Candida species and their functional characterization in the newly emerged pathogen Candida auris
microbiology
Revisiting Ancient Polyploidy in Leptosporangiate Ferns
evolutionary biology
Variation in spontaneous mutation rate and spectrum across the genome of Neurospora crassa
genetics
LANTSA: Landmark-based transferable subspace analysis for single-cell and spatial transcriptomics
bioinformatics
High-throughput Production of Diverse Xenobiotic Metabolites with P450-transduced Huh7 Hepatoma Cell Lines
pharmacology and toxicology
Boosting transformation in wheat by BBM-WUS
plant biology
Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types and cortical subnetworks
neuroscience
N-Terminomic Changes of Neurons During Excitotoxicity Reveals Proteolytic Events Associated with Synaptic Dysfunctions and Potential Targets for Neuroprotection
neuroscience
A consensus protocol for the recovery of mercury methylation genes from metagenomes
microbiology
A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion
microbiology
A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions
molecular biology
Prior selection affects phenotypic and transcriptional response to hypoxia
ecology