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Expressed therapeutic protein yields are predicted by transiently transfected mammalian cell population
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biochemistry
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Integrated platform for multi-scale molecular imaging andphenotyping of the human brain
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bioengineering
|
Genetic engineering of Acidithiobacillus ferridurans with CRISPR-Cas9/dCas9 systems
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bioengineering
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Exogenous application of dsRNA for the control of viruses in cucurbits
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plant biology
|
Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation
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systems biology
|
Overlap across psychotic disorders: A functional network connectivity analysis
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neuroscience
|
Atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells
|
cell biology
|
Endocytosis is required for access of surface-bound cargo to the flagellar pocket of trypanosomes
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cell biology
|
Crumbs complex-directed apical membrane dynamics in epithelial cell ingression
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developmental biology
|
Honeycomb crystallography: Experiment-theory approach for bee comb formation under geometric frustrations
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ecology
|
Sex chromosome differentiation via changes in the Y chromosome repeat landscape in African annual killifishes Nothobranchius furzeri and N. kadleci
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evolutionary biology
|
Detecting patterns of accessory genome coevolution in bacterial species using data from thousands of bacterial genomes
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genomics
|
R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures
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biochemistry
|
Mechanistic insight into the ATP hydrolysis cycle of tick-borne encephalitis virus helicase
|
biochemistry
|
Multi-level cellular and functional annotation of single-cell transcriptomes
|
bioinformatics
|
QTLViewer: An interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations
|
bioinformatics
|
Self-association features of NS1 proteins from different flaviviruses
|
bioinformatics
|
Replacing bar graphs of continuous data with more informative graphics: Are we making progress?
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scientific communication and education
|
Cas9-Mediated Knockout of Ndrg2 Enhances the Regenerative Potential of Dendritic Cells for Wound Healing
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cell biology
|
The Use and Misuse of Composite Environmental Indices
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scientific communication and education
|
Reproducibility problem with a proposed standard method to measure disinfection efficacy
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microbiology
|
Production of novel biosurfactant by a new yeast species isolated from Prunus mume Sieb. et Zucc.
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microbiology
|
Deep learning based feature extraction for prediction and interpretation of sharp- wave ripples
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neuroscience
|
Claudin5 protects the peripheral endothelial barrier in an organ and vessel type-specific manner
|
cell biology
|
Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability
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systems biology
|
Identifying the genes impacted by cell proliferation in proteomics and transcriptomics studies
|
cell biology
|
Integration of multimodal data in the developing tooth reveals candidate dental disease genes
|
developmental biology
|
Decorating chromatin for enhanced genome editing using CRISPR-Cas9
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genetics
|
A modality independent proto-organization of human multisensory areas
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neuroscience
|
Functional architecture of cerebral cortex during naturalistic movie-watching
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neuroscience
|
Reciprocal representation of encoded features by cortical excitatory and inhibitory neuronal populations.
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neuroscience
|
The development of efficient communication in the human connectome.
|
neuroscience
|
Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum supports social novelty preference
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neuroscience
|
Tripartite extended amygdala - basal ganglia CRH circuit drives arousal and avoidance behaviour
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neuroscience
|
Neonate personality affects early-life resource acquisition in a large social mammal
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ecology
|
On the use of relative brain size
|
evolutionary biology
|
miR319-targeted TCP4/LANCEOLATE directly regulates OVATE and auxin responses to modulate tomato gynoecium patterning and fruit morphology
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plant biology
|
EXTERNAL CONTROL OF CANCER CELLULAR DYNAMICS USING ADAPTIVE MODEL PREDICTIVE CONTROL
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systems biology
|
Replication-dependent organisation constrains positioning of long DNA repeats in bacterial genomes
|
genomics
|
Genomes of Two Flying Squid Species Provide Novel Sights into Adaptations of Cephalopods to Pelagic Life
|
genomics
|
Improved sensitivity and resolution of ATAC-seq differential DNA accessibility analysis
|
genomics
|
Allosteric activation of CRISPR-Cas12a requires the concerted movement of the bridge helix and helix 1 of the RuvC II domain
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biochemistry
|
The orphan ligand, Activin C, signals through activin receptor-like kinase 7
|
biochemistry
|
Interpreting the contributions of transcript features to protein abundance prediction models
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bioinformatics
|
Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells
|
cell biology
|
Artificial Hsp100-mediated systems for re-localizing protein aggregates
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cell biology
|
Strain stiffening of the Ndc80 complex
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biophysics
|
Merging of ventral fibers at adhesions drives the remodeling of cellular contractile systems in fibroblasts.
|
cell biology
|
Targeting A-Kinase Anchoring Protein 12 Phosphorylation in Hepatic Stellate Cells Regulates Liver Injury and Fibrosis in Mouse Models
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cell biology
|
Zfp281 inhibits the pluripotent-to-totipotent state transition in mouse embryonic stem cells
|
cell biology
|
FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells
|
cell biology
|
CyberSco.Py: open-source software for event-based, conditional microscopy
|
cell biology
|
Cellular redox metabolism is modulated by the distinct localization of cyclic nucleotide phosphodiesterase 5A isoforms
|
cell biology
|
Aftiphilin regulation of myosin light chain kinase activity promotes actin dynamics and intestinal epithelial barrier function
|
cell biology
|
A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease
|
cell biology
|
KIF24 controls the clustering of supernumerary centrosomes in pancreatic ductal adenocarcinoma cells
|
cell biology
|
Cell size and actin architecture determine force generation in optogenetically activated adherent cells
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biophysics
|
CDKL5 deficiency slows synaptic vesicle endocytosis
|
neuroscience
|
Dual role of an essential HtrA2/Omi protease in the human malaria parasite: maintenance of mitochondrial homeostasis and induction of apoptosis like cell death under cellular stress
|
cell biology
|
Molecular Crowding Facilitates Bundling of IMPDH Polymers and Cytoophidium Formation
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cell biology
|
The X chromosome is a potential polarising signal for asymmetric cell divisions in meiotic cells of a nematode
|
developmental biology
|
Lipid-correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia
|
pathology
|
Concurrent separation of phase-locked and non-phase-locked activity
|
neuroscience
|
Geometrical factors determining dendritic domain intersection between neurons: a modeling study
|
neuroscience
|
Sharp wave ripples in macaque V1 and V4 are modulated by top-down visual attention
|
neuroscience
|
Integrated Diffusion Image Operator (iDIO): A tool for automated configuration and processing of diffusion MRI data
|
neuroscience
|
Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover
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neuroscience
|
Beetles provide directed dispersal of viable spores of a keystone wood decay fungus
|
ecology
|
The chemical basis of metabolic interdependence in microbial communities
|
ecology
|
Eco-evolutionary dynamics of clonal multicellular life cycles
|
evolutionary biology
|
Little skate genome exposes the gene regulatory mechanisms underlying the evolution of vertebrate locomotion
|
evolutionary biology
|
Genetic affinities and adaptation of the South West coast populations of India
|
genetics
|
Assessing behavioral sex differences to chemical cues of predation risk while provisioning nestlings in a hole-nesting bird
|
animal behavior and cognition
|
The physical properties of the stick insect pad secretion are independent of body size
|
bioengineering
|
Neq2X7: a multi-purpose and open-source fusion DNA polymerase for advanced DNA engineering and diagnostics PCR
|
bioengineering
|
Development of a single layer microfluidic device for dynamic stimulation, culture and imaging of mammalian cells
|
bioengineering
|
Unleashing alternative polyadenylation analyses with REPAC
|
bioinformatics
|
HCLC-FC: a novel statistical method for phenome-wide association studies
|
bioinformatics
|
New β-propellers are continuously amplified from single blades in all major lineages of the β-propeller superfamily
|
bioinformatics
|
Comparison and evaluation of data-driven protein stability prediction models
|
bioinformatics
|
Identification of m6A and m5C RNA modifications at single-molecule resolution from Nanopore sequencing
|
bioinformatics
|
iSparse kmeans: a two-step clustering approach for big dynamic functional network connectivity data
|
bioinformatics
|
Hyperglycemic O-GlcNAc transferase activity drives cancer stem cell induction in TNBC
|
cancer biology
|
Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies
|
cancer biology
|
High-fat diet promotes Acute Promyelocytic Leukemia through PPARδ-enhanced self-renewal of preleukemic progenitors
|
cancer biology
|
A Drosophila in vivo chemical screen reveals that combination drug treatment targeting MEK and DGKα mitigates Ras-driven polarity-impaired tumourigenesis.
|
cancer biology
|
Induction of promoter methylation and transcriptional gene silencing upon high pressure spraying of 24-nt small RNAs in Nicotiana benthamiana
|
plant biology
|
Carbon dots boost dsRNA delivery in plants and increase local and systemic siRNA production
|
plant biology
|
High salinity activates CEF and attenuates state transitions in both psychrophilic and mesophilic Chlamydomonas species
|
plant biology
|
Remorin proteins serve as membrane topology scaffolds in plants
|
plant biology
|
Epistatic Modifiers Influence the Expression of Continual Flowering in Strawberry
|
plant biology
|
Increases in vein length compensate for leaf area lost to lobing in grapevine
|
plant biology
|
Individualized Gaussian Process-based Prediction of Memory Performance and Biomarker Status in Ageing and Alzheimer's disease
|
neuroscience
|
Plakoglobin is a mechanoresponsive regulator of naïve pluripotency
|
developmental biology
|
Decomposing predictability to identify dominant causal drivers in complex ecosystems
|
ecology
|
What are you lookin' at?: A role for sexual conflict in coevolution of female display signals and male sensory adaptations?
|
evolutionary biology
|
MR-DoC2: bidirectional causal modeling with instrumental variables and data from relatives
|
genetics
|
Exploring a diverse world of effector domains and amyloid signaling motifs in fungal NLR proteins
|
bioinformatics
|
MiXcan: a Framework for Cell-Type-Specific Transcriptome-Wide Association Studies with an Application to Breast Cancer
|
bioinformatics
|
MSclassifR: an R package for supervised classification of mass spectra with machine learning methods
|
bioinformatics
|
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