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Learning deep representations of enzyme thermal adaptation
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bioinformatics
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Systematic evaluation of chromatin immunoprecipitation sequencing to study histone occupancy in dormancy transitions of grapevine buds
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plant biology
|
Predictable and stable epimutations induced during clonal propagation with embryonic transcription factors
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plant biology
|
Age-dependent lipid droplet-rich microglia worsen stroke outcome in old mice
|
neuroscience
|
Temporal dynamics of competition between statistical learning and episodic memory in intracranial recordings of human visual cortex
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neuroscience
|
Dual STDP processes at Purkinje cells contribute to distinct improvements in accuracy and vigor of saccadic eye movements.
|
neuroscience
|
A conserved immune trajectory of recovery in hospitalized COVID-19 patients
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immunology
|
Size-selective mortality fosters evolutionary changes in collective learning across ontogeny and decision-making in zebrafish, Danio rerio
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ecology
|
Targeting an evolutionarily conserved "E-L-L" motif in the spike protein to develop a small molecule fusion inhibitor against SARS-CoV-2
|
biochemistry
|
Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents
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bioinformatics
|
Nitrogen and phosphorus deficiencies alter primary and secondary metabolites of soybean roots
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plant biology
|
A free classified advertising website is a high-risk unregulated source of domestic wild boar, pot-bellied pigs, and their hybrids with domestic swine in Canada: Implications for African Swine Fever Risk Preparedness
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scientific communication and education
|
Neuroligin-3 in Dopamine Neurons Promotes Behavioral and Neurobiological Adaptations to Chronic Morphine Exposure
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neuroscience
|
Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines
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immunology
|
Direct detection of natural selection in Bronze Age Britain
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evolutionary biology
|
MePMe-seq: Antibody-free simultaneous m6A and m5C mapping in mRNA by metabolic propargyl labeling and sequencing
|
biochemistry
|
Long range electromagnetic effects drive protein-protein approaches: an egg of Coulomb
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biochemistry
|
Molecular Dynamics simulation of TDP-43 RRM in the presence and absence of RNA
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biophysics
|
Quorum sensing as a mechanism to harness the wisdom of the crowds
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microbiology
|
Chlamydia trachomatis suppresses host cell store-operated Ca2+ entry and inhibits NFAT/calcineurin signaling
|
microbiology
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Is virulence phenotype evolution driven exclusively by Lr gene deployment in French Puccinia triticina populations?
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microbiology
|
Dynamic model of bovine brucellosis to investigate control strategies in endemic settings
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microbiology
|
A coevolution experiment reveals parallel mutations in the AcrA-AcrB-TolC efflux pump that contributes to bacterial antibiotic resistance
|
microbiology
|
Tales of Two α-Carboxysomes: the Structure and Assembly of Cargo Rubisco
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microbiology
|
Rapid detection of Staphylococcus aureus and Streptococcus pneumoniae by real-time analysis of volatile metabolites
|
microbiology
|
Phylogenetic analysis of human parainfluenza type 3 virus strains responsible for the outbreak during the COVID-19 pandemic in Seoul, South Korea
|
microbiology
|
Zika virus NS4A hijacks host ANKLE2 to promote viral replication
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molecular biology
|
ANTARCTIC FUNGI: A BIO-SOURCE ALTERNATIVE TO PRODUCE POLYUNSATURATED FATTY ACIDS (PUFAs)
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ecology
|
Hibernation shows no apparent effect on germline mutation rates in grizzly bears
|
evolutionary biology
|
Plasmid stability in fluctuating environments:population genetics of multi-copy plasmids
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evolutionary biology
|
Genome-wide binding of Drosophila Mask reveals its role in maintenance of gene activation by Trithorax group
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genomics
|
In depth exploration of the alternative proteome of Drosophila melanogaster
|
biochemistry
|
A single-cell clusters similarity measure for different batches, datasets, and samples
|
bioinformatics
|
Single cells tell their own story: An updated framework for understanding stochastic variations in cell cycle progression in bacteria
|
biophysics
|
Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy
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cancer biology
|
Targeting Cblb-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cells responses
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cancer biology
|
PeroxiHUB: a modular cell-free biosensing platform using H2O2 as signal integrator
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synthetic biology
|
Strain-specific alterations in gut microbiome and host immune responses elicited by Bifidobacterium pseudolongum
|
microbiology
|
A potential interacting network identified by quantitative proteomics for the sole adenylyl cyclase Cyr1 of Candida albicans
|
microbiology
|
A novel conserved protein in Streptococcus agalactiae, BvaP, is important for vaginal colonization and biofilm formation
|
microbiology
|
Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells
|
molecular biology
|
Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damage
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molecular biology
|
Uterine injury during diestrus leads to embryo spacing defects and perturbations in the COX pathway in subsequent pregnancies
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developmental biology
|
Leaf bacterial community structure and variation in wild ruderal plants are shaped by the interaction of host species and defense chemistry with environment
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ecology
|
Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
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cancer biology
|
The DNA methylation landscape of the human oxytocin receptor gene (OXTR): Recommendations for future research
|
molecular biology
|
AHR agonist ITE boosted PD1 antibodys effects by inhibiting myeloid-derived cells suppressive cells in an orthotopic mouse glioma model
|
cancer biology
|
Validating methods to eradicate Select Agent and phylotype I Ralstonia solanacearum strains reveals that growth in planta increases bacterial stress tolerance
|
microbiology
|
Genetic interaction analysis reveals that Cryptococcus neoformans utilizes multiple acetyl-CoA-generating pathways during infection
|
microbiology
|
Multigrate: single-cell multi-omic data integration
|
bioinformatics
|
Multimodal spatiotemporal phenotyping of human organoid development
|
systems biology
|
Hypothalamic-pituitary-adrenal axis dysfunction worsens epilepsy outcomes and increases SUDEP risk
|
neuroscience
|
Proportional intracranial volume correction differentially biases behavioral predictions across neuroanatomical features and populations
|
neuroscience
|
Chimpanzees organize their social relationships like humans
|
animal behavior and cognition
|
Medial septum glutamate neurons are essential for spatial goal-directed memory
|
neuroscience
|
Invasion genetics of the longhorn crazy ant: the global expansion of a double-clonal reproduction system
|
evolutionary biology
|
Selection on the fly: short term adaptation to an altered sexual selection regime in Drosophila pseudoobscura
|
evolutionary biology
|
Coevolution of Patch Selection in Stochastic Environments
|
evolutionary biology
|
Inbreeding depression in an outbred nine-spined stickleback (Pungitius pungitius) population
|
evolutionary biology
|
Hybrid-derived weedy rice maintains adaptive combinations of alleles associated with seed dormancy
|
evolutionary biology
|
Evolution of transposable element-derived enhancer activity
|
genetics
|
minute: A MINUTE-ChIP data analysis workflow
|
bioinformatics
|
MHC-I binding affinity derived metrics fail to predict tumor specific neoantigen immunogenicity
|
bioinformatics
|
Effect of ambient fluid rheology on oscillatory instabilities in filament-motor systems
|
biophysics
|
Pharmacokinetics of Sustained-Release Buprenorphine and Extended-Release Buprenorphine in Mice with Surgical Catheterization
|
pharmacology and toxicology
|
Does ankle push-off correct for errors in anterior-posterior foot placement relative to center-of-mass state?
|
physiology
|
Adenosine A1R/A3R Agonist AST-004 Reduces Brain Infarction in Mouse and Rat Models of Acute Ischemic Stroke
|
neuroscience
|
Mixture of Learning Strategies Underlies Rodent Behavior in Dynamic Foraging
|
neuroscience
|
The Influence of Neural activity and Neural Cytoarchitecture on Cerebrovascular Arborization: A Computational Model
|
neuroscience
|
Selective V1-to-V4 communication of attended stimuli mediated by attentional effects in V1
|
neuroscience
|
Brain Capillary Pericytes are Metabolic Sentinels that Control Blood Flow through KATP Channel Activity
|
neuroscience
|
Spontaneous myocarditis in mice predisposed to autoimmune disease: Including Vaccination-induced onset
|
immunology
|
A novel method accounting for predictor uncertainty and model transferability of invasive species distribution models
|
ecology
|
Functional Assays Reclassify Suspected Splice-Altering Variants of Uncertain Significance in Mendelian Channelopathies
|
genetics
|
A comprehensive dimensional reduction framework to learn single-cell phenotypic topology uncovers T cell diversity
|
bioinformatics
|
SIMMAM 3.0 - Updating the Toolbox for the Conservation of Marine Mammals
|
bioinformatics
|
Photons guided by axons may enable backpropagation-based learning in the brain
|
biophysics
|
Angiotensin blockade enhances motivational reward learning via enhancing ventral striatal prediction error and frontostriatal communication
|
neuroscience
|
Glassy phase in dynamically-balanced neural networks
|
neuroscience
|
Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in Acute Myeloid Leukemia
|
immunology
|
SLC15A4 favors inflammasome function via mTORC1 signaling and autophagy restraint in dendritic cells
|
immunology
|
Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping
|
genomics
|
Mapping Multiple Factors Mediated Chromatin Interactions to Assess Regulatory Network and Dysregulation of Lung Cancer-Related Genes
|
genomics
|
Limited effects of age on the use of the ankle and counter-rotation mechanism in the sagittal plane
|
bioengineering
|
Probabilistic Brain Extraction in MR Images via Conditional Generative Adversarial Networks
|
bioengineering
|
Fluximplied: A novel approach integrates rate limiting steps and differential expression for pathway analysis
|
bioinformatics
|
UniFuncNet: a flexible network annotation framework
|
bioinformatics
|
Non-ribosomal peptide synthetase domain boundary identification and new motifs discovery based on motif-intermotifs standardized architecture
|
bioinformatics
|
The identification of two newly discovered fluorescent proteins in human glioblastoma
|
cancer biology
|
Heterogeneous multimeric metabolite ion species observed in LC-MS based metabolomics data sets
|
systems biology
|
Model-guided design of the diversity of a synthetic human gut community
|
systems biology
|
Glucagon-like peptide-1 receptor differentially controls mossy cell activity across the dentate gyrus longitudinal axis
|
neuroscience
|
Microarray profiling of hypothalamic gene expression changes in Huntington's disease mouse models
|
neuroscience
|
Optogenetic stimulation of medial septal glutamatergic neurons modulates theta-gamma coupling in the hippocampus
|
neuroscience
|
Developmental phenomics suggests that H3K4 monomethylation catalyzed by Trr functions as a phenotypic capacitor
|
developmental biology
|
Targeted deletion of uterine glandular Foxa2 induces embryonic diapause in mice
|
developmental biology
|
Noninvasive stimulation of the ventromedial prefrontal cortex modulates rationality of human decision-making
|
neuroscience
|
The pyruvate dehydrogenase complex regulates mitophagic selectivity independently of its catalytic activity
|
cell biology
|
Long-term T cell perturbations and waning antibody levels in individuals needing hospitalization for COVID-19
|
immunology
|
The effect of waning on antibody levels and memory B cell recall following SARS-CoV-2 infection or vaccination
|
immunology
|
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