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High-level visual areas act like domain-general filters with strong selectivity and functional specialization
|
neuroscience
|
Subjectivity of time perception alters choice preference for future rewards through fronto-striatal value signal dynamics
|
neuroscience
|
IRON REGULATORY PROTEIN (IRP)-MEDIATED IRON HOMEOSTASIS IS CRITICAL FOR NEUTROPHIL DEVELOPMENT AND DIFFERENTIATION IN THE BONE MARROW
|
immunology
|
Minicollagens play the governing role in polar capsule formation in parasitic cnidarians, the Myxozoa
|
developmental biology
|
Gut microbiota composition in colorectal cancer patients is genetically regulated
|
genetics
|
Cytokine and chemokine profile in patients hospitalized with COVID-19: A comparative study
|
biochemistry
|
Potent and specific human monoclonal antibodies against SARS-CoV-2 Omicron variant by rapid mRNA immunization of humanized mice
|
bioengineering
|
Dynamical Systems Models for Plasma Dilution
|
biophysics
|
Automated neuron tracking inside moving and deforming animals using deep learning and targeted augmentation
|
neuroscience
|
Targeted Anatomical and Functional Identification of Antinociceptive and Pronociceptive Serotonergic Neurons that project to the Superficial Dorsal Horn
|
neuroscience
|
Prime-boost vaccinations with two serologically distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid tested in a hamster COVID-19 model
|
immunology
|
SARS-CoV-2 Omicron potently neutralized by a novel antibody with unique Spike binding properties
|
immunology
|
Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains
|
microbiology
|
Rethinking the role of intraspecific variability in species coexistence
|
ecology
|
Adaptive Magnetic Resonance
|
bioengineering
|
Patch2Self denoising of Diffusion MRI with Self-Supervision and Matrix Sketching
|
neuroscience
|
The cGAS-STING pathway affects vertebral bone but does not promote intervertebral disc cell senescence or degeneration
|
cell biology
|
Instance segmentation of mitochondria in electron microscopy images with a generalist deep learning model.
|
cell biology
|
Two different phospholipases C, Isc1 and Pgc1, cooperate to regulate mitochondrial function
|
cell biology
|
Local actuation of organoids by magnetic nanoparticles
|
developmental biology
|
Modelling global mRNA dynamics during Drosophila embryogenesis reveals a relationship between mRNA degradation and P-bodies
|
developmental biology
|
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation
|
immunology
|
Reproductive tradeoffs govern sexually dimorphic tubular lysosome induction in C. elegans
|
cell biology
|
Gene mutations and molecular evolution of the chikungunya virus E1 and E2 from 2014 to 2019
|
evolutionary biology
|
Per-Pathogen Virulence of HIV-1 subtypes A, C and D
|
evolutionary biology
|
Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression
|
biochemistry
|
Hiplot: a comprehensive and easy-to-use web service boosting publication-ready biomedical data visualization
|
bioinformatics
|
Loop extrusion driven volume phase transition of entangled chromosomes
|
biophysics
|
A model for determining the length distribution of actin filaments in cells
|
biophysics
|
Stability of asymmetric cell division under confinement: A deformable cell model of cytokinesis applied to C. elegans development
|
biophysics
|
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions
|
biophysics
|
Interface resistance of biomolecular condensates
|
biophysics
|
Computational Study of Ion Permeation Through Claudin-4 Paracellular Channels
|
biophysics
|
Analysis of alternative mRNA splicing in vemuraf-enib-resistant melanoma cells
|
cancer biology
|
A mathematical model of antibiotic resistance gene flow from livestock and spread amongst humans
|
zoology
|
Enhanced envelope coding following acoustic trauma is detrimental to neural coding of speech in noise
|
neuroscience
|
Patterns of retrieval-related cortico-striatal connectivity are stable across the adult lifespan
|
neuroscience
|
Development of visual cortex in human neonates are selectively modified by postnatal experience
|
neuroscience
|
High-fidelity dendritic sodium spike generation in human layer 2/3 neocortical pyramidal neurons
|
neuroscience
|
Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating T cells.
|
immunology
|
Bidirectional regulation between AP-1 and SUMO genes modulates inflammatory signaling during Salmonella Typhimurium infection
|
microbiology
|
The coordination between penicillin-binding protein 1a (PBP1a) and the hydrolytic peptidase DacB determines the integrity of bacterial cell poles
|
microbiology
|
Post-transcriptional regulation by copper with a new upstream Open Reading Frame
|
microbiology
|
Modification of the SUMO activating enzyme subunit SAE2 directs SUMO isoform bias required for mitotic fidelity.
|
molecular biology
|
Pathogen-driven induction of a host transcriptome facilitating epithelial-to-mesenchymal transition
|
cell biology
|
Maternal H3K36 and H3K27 HMTs protect germline immortality via regulation of the transcription factor LIN-15B
|
developmental biology
|
Rapid colour changes in a tiny threatened gecko do not impede computer-assisted individual recognition
|
ecology
|
Distilling complex evolutionary histories with shiftPlot
|
evolutionary biology
|
Novel Murine models of Mania and Depression
|
animal behavior and cognition
|
Control algorithms underlying the translational optomotor response
|
animal behavior and cognition
|
Long-term memory in frog-eating bats
|
animal behavior and cognition
|
Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages
|
bioengineering
|
Engineering Principles and Algorithmic Design Synthesis for Ultracompact Bio-Hybrid Perfusion Chip
|
bioengineering
|
Proteochemometric method for pIC50 prediction of Flaviviridae
|
bioinformatics
|
GPCR-IFP: A Web Server for Analyzing G-Protein Coupled Receptor-Ligand Fingerprint Interaction from Experimental Structures
|
bioinformatics
|
Extracting physical characteristics of higher-order chromatin structures from 3D image data
|
bioinformatics
|
Hsp multichaperone complex buffers pathologically modified Tau
|
biophysics
|
Topological action potentials in engineered tissues
|
biophysics
|
Gene expression signature of castrate resistant prostate cancer
|
cancer biology
|
Extracellular matrix guidance determines proteolytic and non-proteolytic cancer cell patterning
|
cancer biology
|
No evidence of induced skin cancer or other skin abnormalities after long term (66 week) chronic exposure to 222-nm far-UVC radiatio
|
cancer biology
|
Humans trade-off energetic cost with fatigue avoidance while walking
|
physiology
|
Mesembryanthemum crystallinum plasma membrane root aquaporins are regulated via clathrin-coated vesicles in response to salt stress
|
plant biology
|
DUF581-9 (At2g44670; FLZ3) negatively regulates SnRK1 activity by interference with T-loop phosphorylation
|
plant biology
|
Water influx is required for CD4+ T cell activation and T cell-dependent antibody responses
|
immunology
|
Plasma iron controls neutrophil production and function
|
immunology
|
DISTINCTIVE FEATURES OF THE RESPIRATORY SYNCYTIAL VIRUS PRIMING LOOP COMPARED TO OTHER NON-SEGMENTED NEGATIVE STRAND RNA VIRUSES
|
microbiology
|
Genetic and environmental drivers of large-scale epigenetic variation in Thlaspi arvense
|
evolutionary biology
|
Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models
|
genomics
|
DNA co-methylation has a stable structure and is related to specific aspects of genome regulation
|
bioinformatics
|
Technology applications in bovine gait analysis: a scoping review
|
zoology
|
Female reproductive fluid composition differs based on mating system in Peromyscus mice
|
evolutionary biology
|
Projective LDDMM: Spatially Reconstructing a Story of Rostrally-Dominant Tau in Alzheimer's Disease
|
bioengineering
|
Ubiquitous lognormal distribution of neuron densities across mammalian cerebral cortex
|
neuroscience
|
Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy
|
neuroscience
|
Biocompatible polymers for scalable production of human neural organoids
|
neuroscience
|
Transcriptomic similarity in the mouse and human brain
|
neuroscience
|
Impact of maternal protein restriction on hypoxia-inducible factor (HIF) expression in male fetal kidney development
|
developmental biology
|
A single amino acid transporter controls the uptake of priming-inducing beta-amino acids and the associated trade-off between induced resistance and plant growth.
|
plant biology
|
Alpha-mannosidase-2 modulates arbovirus infection in a pathogen- and Wolbachia-specific manner in Aedes aegypti mosquitoes
|
microbiology
|
Establishment of an efficient transformation and CRISPR/Cas9-mediated gene editing system in Chinese local planting cassava (Manihot esculenta Crantz) cultivar SC8
|
molecular biology
|
Combining quadrat, rake and echosounding to estimate submerged aquatic vegetation biomass at the ecosystem scale
|
ecology
|
Transcriptomic analysis of the C3-CAM transition in Cistanthe longiscapa, a drought tolerant plant in the Atacama Desert
|
plant biology
|
Timely sleep coupling: spindle-slow wave synchrony is linked to early amyloid-β burden and predicts memory decline
|
neuroscience
|
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in dendritic spine development
|
neuroscience
|
COVID-19 patients have increased levels of membrane-associated and soluble CD48
|
immunology
|
Pre-exposure to mRNA-LNPs reprograms adaptive and innate immune responses in an inheritable fashion
|
immunology
|
Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex
|
neuroscience
|
Glial control of sphingolipid levels sculpts diurnal remodeling of sleep circuitry
|
neuroscience
|
Synapses in oligodendrocyte precursor cells are dynamic and contribute to Ca2+ activity
|
neuroscience
|
The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton
|
neuroscience
|
Inducible depletion of Scleraxis-lineage cells during tendon healing impairs multi-scale restoration of tendon structure
|
cell biology
|
Coverage-preserving sparsification of overlap graphs for long-read assembly
|
bioinformatics
|
Geology and discovery record of the Trinil Pithecanthropus erectus site, Java
|
paleontology
|
The rate of information transmission through the MAPK/ERKsignaling pathway stimulated in a pulsatile manner
|
systems biology
|
Gene Co-expression Connectivity Predicts Gene Targets Underlying High Ionic Liquid Tolerance in Yarrowia lipolytica
|
systems biology
|
Diminished distractor filtering with increased perceptual load and sustained effort explains attention deficit in post-stroke fatigue
|
neuroscience
|
The combination of Hebbian and predictive plasticity learns invariant object representations in deep sensory networks
|
neuroscience
|
EXONIZATION BY THE EMERGENCE OF A CLEAVAGE-POLYADENYLATION SITE
|
evolutionary biology
|
Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1 mediated HSR
|
genetics
|
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