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Plasmid characterization in bacterial isolates of public health relevance in a tertiary healthcare facility in Kilimanjaro, Tanzania
|
genomics
|
Towards reliable quantification of cell state velocities
|
bioinformatics
|
DENVIS: scalable and high-throughput virtual screening using graph neural networks with atomic and surface protein pocket features
|
bioinformatics
|
Complementing machine learning-based structure predictions with native mass spectrometry
|
biophysics
|
MINSTED nanoscopy enters the Angstrom localization range
|
biophysics
|
Proteomic profiling identifies co-regulated expression of splicing factors as a characteristic feature of intravenous leiomyomatosis
|
cancer biology
|
KAT5 activity regulates G0-like states in human gliomas
|
cancer biology
|
Dietary Induced Dynamic Plasticity of Intestinal Stem Cells and the Mucosa in Elevating Risk for Tumor Development
|
cancer biology
|
Toxicological Analysis of Poly-Lactide Co-Glycolide Microparticles, Chitosan Nanoparticles and Poly(Anhydride) Nanoparticles in Vero Cell
|
pharmacology and toxicology
|
Single-nucleotide substitution determines pollen production in Japanese cedar
|
plant biology
|
Generalized Method of Moments improves parameter estimation in biochemical signaling models of time-stamped single-cell snapshot data
|
systems biology
|
Sparse coding models predict a spectral bias in the development of primary visual cortex (V1) receptive fields
|
neuroscience
|
Reproducible Tract Profiles (RTP2): from diffusion MRI acquisition to clinical practice and research
|
neuroscience
|
Altered PVN-to-CA2 hippocampal oxytocin pathway and reduced number of oxytocin-receptor expressing astrocytes in heart failure rats
|
neuroscience
|
A murine model of hnRNPH2-related neurodevelopmental disorder recapitulates clinical features of human disease and reveals a mechanism for genetic compensation of HNRNPH2
|
neuroscience
|
Hyper-adaptation in the Human Brain: Functional and structural changes in the foot section of the primary motor cortex in a top wheelchair racing Paralympian
|
neuroscience
|
Fine oculomotor knowledge enhances high-acuity vision
|
neuroscience
|
Characterizing brain imaging features associated with ADAS-Cog13 sub-scores with 3D convolutional neural networks
|
neuroscience
|
The Cocktail Party Effect in Post-Stroke Fatigue: an EEG study
|
neuroscience
|
pTDP-43 aggregates accumulate in the gut and other non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis
|
neuroscience
|
Causal Inference on Neuroimaging Data with Mendelian Randomisation
|
neuroscience
|
A multi-scale fusion CNN model based on adaptive transfer learning for multi-class MI-classification in BCI system
|
neuroscience
|
Beneficial effects of prolonged 2-phenylethyl alcohol inhalation on chronic distress-induced anxio-depressive-like phenotype in female mice
|
neuroscience
|
Condensin positioning at telomeres by Taz1 promotes telomere disjunction in anaphase
|
cell biology
|
Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
|
cell biology
|
Towards understanding diversity, endemicity and global change vulnerability of soil fungi
|
ecology
|
A novel PLS1 c.981+1G>A variant causes autosomal-dominant hereditary hearing loss in a family via up-regulation of the PI3K-Akt signaling pathway
|
genetics
|
A novel class of long small RNAs associates with Argonaute1 and is up-regulated by nutrient deprivation in the alga Chlamydomonas
|
genetics
|
Tissue-adjusted pathway analysis of cancer (TPAC)
|
genomics
|
Lack of self-medication by fungus infected Lasius platythorax ants in a multitrophic experiment
|
animal behavior and cognition
|
Characterization of Quantum Dots with Hyperspectral Fluorescence Microscopy for Multiplexed Optical Imaging of Biomolecules
|
bioengineering
|
Fragment-Based Ligand Generation Guided By Geometric Deep Learning On Protein-Ligand Structure
|
bioengineering
|
Bioinformatics Analysis of next generation sequencing data for Risk Prediction in Patients with Type 1 diabetes mellitus
|
bioinformatics
|
Phenotype to genotype mapping using supervised and unsupervised learning
|
bioinformatics
|
Modeling of Aryl Hydrocarbon Receptor Pathway Intrinsic Immunometabolic Role using Glioblastoma Stem Cells and Patient-Derived Organoids
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cancer biology
|
SPDEF promotes the classical subtype of pancreatic ductal adenocarcinoma.
|
cancer biology
|
Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy
|
pathology
|
Temporal integration of rod signals in luminance and chromatic pathways
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physiology
|
Novel diversity panel facilitates genomic dissection of lodging in tef (Eragrostis tef)
|
plant biology
|
Heterocyclic aromatic amines (HAAs) target mitochondrial physiology
|
neuroscience
|
Emotional intensity can enrich or degrade memories: impact of the amygdalar pathway on hippocampus through inhibitory neurons
|
neuroscience
|
Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals
|
developmental biology
|
Understandable Multifunctionality Measures Using Hill Numbers
|
ecology
|
Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution
|
evolutionary biology
|
Standardization of cytological behavior of pollens in sorghum by Image analysis
|
genetics
|
Symbolic quantitative cognition in wild zebrafish (Danio rerio)
|
animal behavior and cognition
|
Evidence-based calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for clinical use of PP3/BP4 criteria
|
bioinformatics
|
Fate mapping melanoma persister cells through regression and into recurrent disease in adult zebrafish
|
cancer biology
|
POU2AF2/C11orf53 functions as a co-activator of POU2F3 by maintaining chromatin accessibility and enhancer activity
|
cancer biology
|
Distribution and frequency of salivary gland tumours: an international multicenter study
|
pathology
|
Spatio-temporal modeling reveals a layer of tunable control circuits for the distribution of cytokines in tissues
|
systems biology
|
Behavioral and dopaminergic signatures of resilience
|
neuroscience
|
Maternal separation induces autism spectrum disorder in young rhesus monkeys
|
neuroscience
|
What happens after an error?
|
neuroscience
|
Antimicrobial peptide secretion protects endosymbionts from bacteriome autoimmunity in insects
|
immunology
|
Disruption of the plastid-hosted iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability
|
microbiology
|
Transcriptional analysis identifies overlapping and tissue-distinct profiles between Kaposi sarcoma tumors of the skin and gastrointestinal tract
|
microbiology
|
A role of Lck annular lipids in the steady upkeep of active Lck in T cells
|
cell biology
|
The motif composition of variable-number tandem repeats impacts gene expression
|
genomics
|
Functional analysis of the N-terminal region of Vibrio FlhG, a MinD-type ATPase in flagellar number control
|
biochemistry
|
Studies of a siderophore-producing cyclization domain: A refined proposal of substrate binding
|
biochemistry
|
Harnessing the power of technical and natural variation in 116 yeast datasets to benchmark long read assembly pipelines
|
bioinformatics
|
Ratiometric Sensing of Redox Environments Inside Individual Carboxysomes Trapped in Solution
|
biophysics
|
Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography
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pathology
|
If this title is funny, will you cite me? Citation impacts of humour and other features of article titles in ecology and evolution
|
scientific communication and education
|
Strategies to Identify and Edit Improvements in Synthetic Genome Segments Episomally.
|
synthetic biology
|
Alpha-1 Antitrypsin Limits Neutrophil Extracellular Trap Disruption of Airway Epithelial Barrier Function
|
immunology
|
Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies
|
immunology
|
Meta-analysis of the autism gut microbiome identifies factors influencing study discrepancies and machine learning classification
|
microbiology
|
Activation of the chemokine receptor CCR1 and preferential recruitment of Gαi suppress RSV replication: implications for developing novel RSV treatment strategies
|
microbiology
|
A South American mouse morbillivirus sheds light into a clade of rodent-borne morbilliviruses
|
microbiology
|
The phospholipase VlsPLA2 from the plant pathogen Verticillium longisporum is a virulence factor targeting host nuclei and suppressing PTI-related hypersensitive response
|
microbiology
|
Molecular determinants of the Bacillus subtilis chromosome origin basal unwinding system
|
microbiology
|
The genome wide analysis deciphered virulence factors and secondary metabolites of Chryseobacterium and description of Chryseobacterium indicum sp. nov.
|
microbiology
|
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect SUMO conjugate types.
|
molecular biology
|
Coenzyme Q regulates UCP1 expression and thermogenesis through the integrated stress responses
|
cell biology
|
Modeling the Evolution of Rates of Continuous Trait Evolution
|
evolutionary biology
|
Increased male investment in sperm competition results in offspring of lower quality
|
evolutionary biology
|
The genetic and biochemical determinants of mRNA degradation rates in mammals
|
genomics
|
Programmed-DNA Elimination in the free-living nematodes Mesorhabditis
|
genomics
|
One-Pot Exosome Proteomics Enabled by a Photocleavable Surfactant
|
biochemistry
|
Wochenende - modular and flexible alignment-based shotgun metagenome analysis
|
bioinformatics
|
Universal dynamics of biological pattern formation in spatio-temporal morphogen variations
|
biophysics
|
AlphaFold encodes the principles to identify high affinity peptide binders
|
biophysics
|
Vimentin intermediate filament assembly is a reversible process
|
biophysics
|
Proteomic identification of the interactome of stalled ribosome nascent chain complexes translating the thylakoid membrane protein D1
|
plant biology
|
Configurable Compartmentation Enables In vitro Reconstitution of Sustained Synthetic Biology Systems
|
synthetic biology
|
Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs
|
systems biology
|
A microfluidic-based model of nociceptor sensitization reveals a direct activation of sensory axons by prostaglandin E2
|
neuroscience
|
Microglial amyloid beta clearance is driven by PIEZO1 channels
|
neuroscience
|
Low-Toxin Clostridioides difficile RT027 Strains Exhibit Robust Virulence
|
microbiology
|
A Biological Signature for the Inhibition of Outer Membrane Lipoprotein Biogenesis
|
microbiology
|
Development of ONT-cappable-seq to unravel the transcriptional landscape of Pseudomonas phages
|
genomics
|
Location of the TEMPO moiety of TEMPO-PC in phosphatidylcholine bilayers is membrane phase-dependent
|
biophysics
|
Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironment
|
cancer biology
|
Mitochondrial Matrix Protease ClpP Agonists inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis
|
cancer biology
|
Hepatocyte-specific loss of LAP2α reduces hepatic steatosis in male mice by enhancing LMNA-mediated transcriptional regulation
|
physiology
|
Structural and functional insight into the plant unique multimodular triphosphosphate tunnel metalloenzymes of Arabidopsis thaliana
|
plant biology
|
Accurate Protein Domain Structure Annotation with DomainMapper
|
bioinformatics
|
Fragment libraries designed to be functionally diverse recover protein binding information more efficiently than standard structurally diverse libraries
|
bioinformatics
|
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