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Knowledge graph analytics platform with LINCS and IDG for Parkinson's disease target illumination
|
bioinformatics
|
Hidden Transcriptome Signature in Autism Spectrum Disorder (ASD) is Attributed to the Interpatient Heterogeneity
|
bioinformatics
|
Packpred: Predicting the functional effect of missense mutations
|
bioinformatics
|
Unbuttoning the impact of N501Y mutant RBD on viral entry mechanism: A computational insight
|
bioinformatics
|
Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction
|
biophysics
|
Secretome of senescent hepatoma cells modulate macrophage polarization and neutrophil extracellular traps formation
|
cancer biology
|
Rejuveinix Reverses Severe Inflammatory Lung Damage in a Mouse Model of Fatal Sepsis
|
pharmacology and toxicology
|
Orchestration of the stilbene synthase gene family and their regulators by subgroup 2 MYB genes
|
plant biology
|
Multivariate analysis of strawberry experiments: where are we now and where can we go?
|
plant biology
|
Orchestrated Excitatory and Inhibitory Learning Rules Lead to the Unsupervised Emergence of Up-states and Balanced Network Dynamics
|
neuroscience
|
Stabilized Supralinear Network: Model of Layer 2/3 of the Primary Visual Cortex
|
neuroscience
|
Animal-to-Animal Variability in Hippocampal Remapping
|
neuroscience
|
Going beyond rote auditory learning: Neural patterns of generalized auditory learning
|
neuroscience
|
Data-driven filtration and segmentation of mesoscale neural dynamics
|
neuroscience
|
Negative correlation between average speed and average turning angle naturally arises for sparsely sampled cell movement data
|
immunology
|
Intermittent bulk release of human cytomegalovirus through multivesicular bodies
|
microbiology
|
Functional insights of two MATE transporters from Vibrio fluvialis
|
microbiology
|
YhcB (DUF1043), a novel cell division protein conserved across gamma-proteobacteria
|
microbiology
|
Rapid inactivation of SARS-CoV-2 on copper touch surfaces determined using a cell culture infectivity assay
|
microbiology
|
Spatial and temporal dynamics of SAR11 marine bacteria sampled across a nearshore to offshore transect in the tropical Pacific Ocean
|
microbiology
|
Genomic insights of high-risk clones of ESBL-producing Escherichia coli isolated from community infections and commercial meat in Southern Brazil
|
microbiology
|
Alveolar type II cells harbouring SARS-CoV-2 show senescence with a proinflammatory phenotype
|
cell biology
|
Benchmarking Oxford Nanopore read assemblers for high-quality molluscan genomes
|
genomics
|
Single-cell and single-variant resolution analysis of clonal evolution in human liver cancer
|
genomics
|
Insights into Genome Recoding from the Mechanism of a Classic +1-Frameshifting tRNA
|
biochemistry
|
A genome wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity
|
biochemistry
|
Dynamic Detection and Reversal of Myocardial Ischemia Using an Artificially Intelligent Bioelectronic Medicine
|
bioengineering
|
Cas9-cleavage sequences in minimal plasmids enhance non-viral genome targeting of CARs in primary human T cells
|
bioengineering
|
The Crystal Structure of Bromide-bound GtACR1 Reveals a Pre-Activated State in the Transmembrane Anion Tunnel
|
biophysics
|
Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies
|
biophysics
|
Flagellin triggers mesophyll dehydration: An early PTI defense against bacterial establishment in intercellular spaces
|
plant biology
|
An amiRNA screen uncovers redundant CBF & ERF34/35 transcription factors that differentially regulate arsenite and cadmium responses
|
plant biology
|
Variability of the Surface Area of the V1, V2, and V3 Maps in a Large Sample of Human Observers
|
neuroscience
|
Novel antibiotic mode of action by repression of promoter isomerisation
|
molecular biology
|
Identifying, Protecting and Managing Stopover Habitats for Wild Whooping Cranes on U.S. Army Corps of Engineers Lakes
|
ecology
|
Homology between the flagellar export apparatus and ATP synthetase: evidence from synteny predating the Last Universal Common Ancestor
|
evolutionary biology
|
Genome-wide characterization and identification of synonymous codon usage patterns in Plasmodium knowlesi
|
genomics
|
Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traits
|
genomics
|
Amyloid-β peptide dimers undergo a random coil to β-sheet transition in the aqueous phase but not at the neuronal membrane
|
biophysics
|
Transcriptomics data availability and reusability in the transition from microarray to next-generation sequencing
|
bioinformatics
|
Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage
|
cell biology
|
An RNAi screen in C. elegans for genes that play a role in secretion and cleavage of VAPB MSP domain.
|
cell biology
|
Translational control of lipogenesis links protein synthesis and phosphoinositide signaling with nuclear division
|
cell biology
|
In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions
|
cell biology
|
Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-derived Factor Receptor (PEDF-R)
|
biochemistry
|
Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau
|
biochemistry
|
Fabrication of silver doped nano hydroxyapatite-carrageenan hydrogels for articular cartilage applications
|
bioengineering
|
Designing novel biochemical pathways to commodity chemicals using ReactPRED and RetroPath2.0
|
bioengineering
|
Cellsnp-lite: an efficient tool for genotyping single cells
|
bioinformatics
|
scJoint: transfer learning for data integration of single-cell RNA-seq and ATAC-seq
|
bioinformatics
|
metaGEM: reconstruction of genome scale metabolic models directly from metagenomes.
|
bioinformatics
|
eSPRESSO: a spatial self-organizing-map clustering method for single-cell transcriptomes of various tissue structures using graph-based networks
|
bioinformatics
|
Mechanistic Insight from Full Quantum Mechanical Modeling: Laccase as a Detoxifier of Aflatoxins
|
biophysics
|
SERS uncovers the link between conformation of cytochrome c heme and mitochondrial membrane potential
|
biophysics
|
The DAXX-SREBP axis promotes oncogenic lipogenesis and tumorigenesis
|
cancer biology
|
A Nanoceutical Agent for Chemoprevention of Bilirubin Encephalopathy
|
pharmacology and toxicology
|
Disrupted dynamic functional network connectivity among cognitive control networks in the progression of Alzheimer's disease
|
neuroscience
|
Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface
|
immunology
|
Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses
|
immunology
|
A metagenomic-based stufy of two sites from the Barbadian reef system
|
microbiology
|
Real-time respiration changes as a viability indicator for rapid antibiotic susceptibility testing in a microfluidic chamber array
|
microbiology
|
A new method for improving extraction efficiency and purity of urine and plasma cell-free DNA
|
molecular biology
|
RNA pull-down-Confocal Nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-Synuclein levels
|
molecular biology
|
PD-L1+ and Hyal2+ myeloid cells in renal cell carcinoma: a case report
|
cell biology
|
Estimation of the Acetylcholinesterase activity of honey bees in Nepal
|
ecology
|
Diversity in olfactory receptor repertoires is associated with dietary specialization in a genus of frugivorous bat
|
evolutionary biology
|
Time-dependent pleiotropic phenotypes are caused by progressive DNA polymerase α deficiency in zebrafish
|
genetics
|
LAVA: An integrated framework for local genetic correlation analysis
|
genetics
|
Comparing instance segmentation methods for analyzing clonal growth of single cells in microfluidic chips
|
bioengineering
|
Comprehensive profiling of genomic and transcriptomic differences between risk groups of lung adenocarcinoma and lung squamous cell carcinoma
|
bioinformatics
|
SANS serif: alignment-free, whole-genome based phylogenetic reconstruction
|
bioinformatics
|
Wide occurrence of putative mobilized colistin resistance genes in the human gut microbiome
|
bioinformatics
|
Cellular mechanisms of heterogeneity in NF2-mutant schwannoma
|
cancer biology
|
Massively parallel characterization of engineered transcript isoforms using direct RNA sequencing
|
synthetic biology
|
Distribution of Huntington's disease Haplogroups in Indian population
|
neuroscience
|
Spontaneous and deliberate modes of creativity: Multitask eigen-connectivity analysis captures latent cognitive modes during creative thinking
|
neuroscience
|
Colour Ambiguity In Real Scenes And The Role Of Perceptual Organisation
|
neuroscience
|
In vivo super-resolution track-density imaging for thalamic nuclei identification
|
neuroscience
|
Effects of chronic lithium treatment on anxious behaviors and serotonergic genes expression in the midbrain raphe nuclei in defeated male mice
|
neuroscience
|
Specific cognitive signatures of information seeking in controllable environments
|
neuroscience
|
Lithium ions display weak interaction with amyloid-beta (Aβ) peptides and have minor effects on their aggregation
|
biochemistry
|
De novo germline mutation in the Dual Specificity Phosphatase 10 gene accelerates autoimmune diabetes in Non-Obese Diabetic (NOD) mice
|
immunology
|
S. aureus-serine protease-like protein B (SplB) activates PAR2 and induces endothelial barrier dysfunction
|
immunology
|
6-gingerol interferes with amyloid-beta (Aβ) peptide aggregation
|
biochemistry
|
The engineered peptide construct NCAM1-Aβ inhibits aggregation of the human prion protein (PrP)
|
biochemistry
|
An integrative model of plant gravitropism linking statoliths position and auxin transport
|
biophysics
|
POT1 Stability and Binding Measured by Fluorescence Thermal Shift Assays
|
biophysics
|
Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains
|
biophysics
|
FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes
|
biophysics
|
Microsecond resolved infrared spectroscopy on non-repetitive protein reactions by applying caged-compounds and quantum cascade laser frequency combs
|
biophysics
|
Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2
|
biophysics
|
Learning attention-controllable border-ownership for objectness inference and binding
|
neuroscience
|
A Practical Guide to Sparse Clustering for Studying Molecular Development of the Human Brain
|
neuroscience
|
More than expected: the abundance of yellow-legged gulls Larus michahellis breeding in the historic centre of Venice and the initial effects of the new waste collection policy on the population
|
ecology
|
Viral competence data improves rodent reservoir predictions for American orthohantaviruses
|
ecology
|
Predicting The Yields Of Species Occupying A Single Trophic Level With Incomplete Information: Two Approximations Based On The Lotka-Volterra Generalized Equations
|
ecology
|
Distribution modeling of Lantana camara and identification of hotspot for future management of the species in the lower Shivalik region of Uttarakhand, India
|
ecology
|
Identification of Discriminative Gene-level and Protein-level Features Associated with Gain-of-Function and Loss-of-Function Mutations
|
genetics
|
Moment-based approximations for the Wright-Fisher model of population dynamics under natural selection at two linked loci
|
genetics
|
The histologic phenotype of lung cancers may be driven by transcriptomic features rather than genomic characteristics
|
genomics
|
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