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Detection of low numbers of bacterial cells in pharmaceutical drug product using Raman Spectroscopy and PLS-DA multivariate analysis.
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bioengineering
|
An outstanding bacterial membranome requires CRISPR-Cas systems to avoid the intervention of phages
|
bioinformatics
|
The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer
|
cancer biology
|
Cancer stem cell-derived extracellular vesicles preferentially target MHCII- macrophages and PD1+ T cells in the tumor microenvironment
|
cancer biology
|
SWAP1-SFPS-RRC1 splicing factor complex modulates pre-mRNA splicing to promote photomorphogenesis in Arabidopsis
|
plant biology
|
Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy
|
plant biology
|
p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation
|
neuroscience
|
Human Cytomegalovirus induces neuronal enolase to support virally-mediated metabolicremodeling
|
microbiology
|
Donor strand complementation, isopeptide bonds and glycosylation stabilise highly resilient archaeal thread filaments
|
microbiology
|
Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted 177Lu-DOTATATE
|
molecular biology
|
Investigating the impact of database choice on the accuracy of metagenomic read classification for the rumen microbiome
|
genomics
|
Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
|
genomics
|
The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import by enhancing assembly of the TOM complex
|
biochemistry
|
Conditional covalent lethality driven by oncometabolite accumulation
|
biochemistry
|
On the Prediction of non-CG DNA Methylation
|
bioinformatics
|
Trimethylamine N-oxide (TMAO) enhances substrate mechanical stability probed by single molecule magnetic tweezers
|
biophysics
|
Pervasive transcription enhances the accessibility of H-NS-silenced promoters and generates bistability in Salmonella virulence gene expression
|
microbiology
|
Mycobacterium tuberculosis transcriptional regulator Rv1019 is upregulated in hypoxia and negatively regulates Rv3230c-Rv3229c operon encoding enzymes in the oleic acid biosynthetic pathway
|
molecular biology
|
Assessing pyrethroid resistance status in the Culex pipiens complex (Diptera: Culicidae) from the northwest suburbs of Chicago, Illinois using Cox regression of bottle bioassays and other detection tools
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pharmacology and toxicology
|
Fear engrams and NPYergic circuit in the dorsal dentate gyrus determine remote fear memory generalization.
|
neuroscience
|
Achieving improved accuracy for imputation of ancient DNA
|
genomics
|
Assessment of local potato cultivars found in Cis-Himalayan region of West Bengal through morphology and biochemical profiling
|
plant biology
|
Evolutionarily conserved effects of Notch signaling drive intestinal graft-versus-host disease in mice and non-human primates
|
immunology
|
Boid Inclusion Body Disease (BIBD) Is Also a Disease of Wild Boa Constrictors
|
microbiology
|
Secondary metabolites produced during Aspergillus fumigatus and Pseudomonas aeruginosa biofilm formation
|
microbiology
|
Lola-I is a developmentally regulated promoter pioneer factor
|
genomics
|
Proteomics identifies substrates and a novel component in hSnd2-dependent ER protein targeting
|
cell biology
|
Chromosome-level draft assemblies of the snow leopard, African leopard, and tiger (Panthera uncia, Panthera pardus pardus, and Panthera tigris)
|
genomics
|
Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment
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cancer biology
|
Elongated Hypocotyl 5 (HY5) regulates BRUTUS (BTS) to maintain Iron homeostasis in Arabidopsis thaliana.
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plant biology
|
Survivin prevents the Polycomb Repressor Complex 2 from methylating Histone 3 lysine 27
|
molecular biology
|
Single cell RNA-seq identifies inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma
|
cell biology
|
Hydrothermal sulphur bacteria enhance mercury availability for coastal marine organisms
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ecology
|
Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters.
|
genomics
|
Canine lineages reveal genetic drivers of dog behavioral diversification
|
genomics
|
Infection signaling and antimicrobial wound care in an ant society
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animal behavior and cognition
|
Integrated molecular analysis reveals two distinct subtypes of pure seminoma of the testis
|
cancer biology
|
Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota
|
systems biology
|
Optimized Repli-seq: Improved DNA Replication Timing Analysis by Next-Generation Sequencing
|
genomics
|
Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
|
neuroscience
|
Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration
|
developmental biology
|
Real-time monitoring of endogenous Fgf8a gradient attests to its role as a morphogen during zebrafish gastrulation
|
developmental biology
|
The molecular architecture of cell cycle arrest
|
cell biology
|
Targeting Neutrophils Extracellular Traps (NETs) reduces multiple organ injury in a COVID-19 mouse model
|
pharmacology and toxicology
|
Weak seed banks influence the signature and detectability of selective sweeps
|
evolutionary biology
|
Utilising hippocampal neuronal calcium activity in mouse CA1 for a multimodal optical brain-computer interface
|
bioengineering
|
Chemotherapy Signatures Map Evolution of Therapy-Related Myeloid Neoplasms
|
cancer biology
|
Genomic And Molecular Characterization Of The Wheat Streak Mosaic Virus Resistance Locus 2 (Wsm2) In Common Wheat (Triticum Aestivum. L)
|
pathology
|
Assessment of Culicidae collection methods for xenomonitoring lymphatic filariasis in malaria co-infection context in Burkina Faso
|
pathology
|
Dietary fatty acids modulate the endocannabinoid system in rat submandibular gland
|
pathology
|
Aperiodic brain activity and response to anesthesia vary in disorders of consciousness
|
neuroscience
|
Fine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits
|
neuroscience
|
Extensive protected area coverage and an updated global population estimate for the Endangered Madagascar Serpent-eagle identified from species-habitat associations using remote sensing data
|
ecology
|
Differentiation of thermal reaction norms between marginal and core populations of a northward expanding parasitoid
|
evolutionary biology
|
The rediscovery of a relict unlocks the first global phylogeny of whip spiders (Amblypygi)
|
genomics
|
Enhanced recovery of single-cell RNA-sequencing reads for missing gene expression data
|
genomics
|
Pre-analytical processing of plasma and serum samples for combined proteome and metabolome analysis
|
biochemistry
|
Relationships between post-stroke mediolateral stepping characteristics, walking speed, balance performance, and balance confidence
|
bioengineering
|
A Comparison of Dimension Reduction Methods for Cytometry by Time-of-Flight Data
|
bioinformatics
|
Faster SARS-CoV-2 sequence validation and annotation for GenBank using VADR
|
bioinformatics
|
Prediction of allosterically acting mutations using MD simulations and Rosetta
|
biophysics
|
Elevated arginine levels in liver tumors promote metabolic reprogramming and tumor growth
|
cancer biology
|
Discovery of new senolytics using machine learning
|
cancer biology
|
MycoPhylo experiment reveals how mycorrhiza types and phylogenetic relationships affect soil biodiversity and functioning
|
plant biology
|
Robustness of organ morphology is associated with modules of co-expressed genes related to plant cell wall
|
plant biology
|
Inflammation as a Silent Partner in Opioid Addiction: A Regulatory Logic Model
|
systems biology
|
Approximating Solutions of the Chemical Master Equation using Neural Networks
|
systems biology
|
The arthropod associates of 155 North American cynipid oak galls
|
zoology
|
Efficacy and Specificity of Melanopsin Reporters for Retinal Ganglion Cells
|
neuroscience
|
Cortical response variability is driven by local excitability changes with somatotopic organization
|
neuroscience
|
Aquaporin 4 is differentially increased and depolarized in association with tau and amyloid-beta
|
neuroscience
|
Fixational eye movements as active sensation for high visual acuity
|
neuroscience
|
Episodic memory retrieval affects the onset and dynamics of evidence accumulation during value-based decisions
|
neuroscience
|
Neurofeedback training for improving motor performance in healthy adults: A systematic review and meta-analysis
|
neuroscience
|
Mechanisms regulating the frequency of inhibition-based gamma oscillations in primate prefrontal and parietal cortices
|
neuroscience
|
Dynamic neural reconstructions of attended object location and features using EEG
|
neuroscience
|
Dynamic Features of Chromosomal Instability during Culture of Induced Pluripotent Stem Cells
|
cell biology
|
BioNE: Integration of network embeddings for supervised learning
|
bioinformatics
|
Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2
|
biophysics
|
The double round-robin population unravels the genetic architecture of grain size in barley
|
plant biology
|
A role for the circadian transcription factor NPAS2 in the progressive loss of non-rapid eye movement sleep and increased arousal during fentanyl withdrawal in male mice
|
neuroscience
|
Coupling of NOD2 to GIV is Required for Bacterial Sensing
|
immunology
|
Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity
|
microbiology
|
Extensive diversity of RNA viruses in ticks revealed by metagenomics in northeastern China
|
microbiology
|
P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants
|
microbiology
|
The conserved histone chaperone Spt6 facilitates DNA replication and mediates genome instability
|
molecular biology
|
Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain
|
molecular biology
|
Mediator-RNA Polymerase II Interactions Critical for Transcriptional Activation Are Mediated by the N-terminal Half of MED14 and C-terminal Domain of RPB1
|
molecular biology
|
Functional genomics analysis identifies impairment of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome.
|
developmental biology
|
CLASP1 is essential for neonatal lung function and survival in mice
|
developmental biology
|
Mutation rates and adaptive variation among the clinically dominant clusters of Mycobacterium abscessus
|
genomics
|
Cocoa Extract Exerts Sex-Specific Effects in an Aggressive Hyperglycemia Model: A Pilot Study
|
biochemistry
|
Inhibiting succinate release worsens cardiac reperfusion injury by enhancing mitochondrial reactive oxygen species generation
|
biochemistry
|
Computationally Guided Design of Novel Angiotensin Converting Enzyme Inhibitors
|
biochemistry
|
A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage
|
biochemistry
|
Pericytes and Astrocytes Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model
|
bioengineering
|
Biomolecular condensates govern PARP inhibitor trapping and present mechanisms of resistance
|
biophysics
|
Loss of Myosin-1e biases MMTV-PyMT induced breast cancer towards a 4 differentiated and secretory state
|
cancer biology
|
Fic-mediated AMPylation tempers the Unfolded Protein Response during physiological stress
|
physiology
|
Integrative human atrial modeling unravels interactive PKA and CaMKII signaling as key determinant of atrial arrhythmogenesis
|
physiology
|
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