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Expression of the Bacillus thuringiensis vip3A insecticidal toxin gene is activated at the onset of stationary phase by VipR, an autoregulated transcription factor
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microbiology
|
5' transgenes drive leaky expression of 3' transgenes in inducible bicistronic vectors
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molecular biology
|
Identification of Transient Intermediates During Spliceosome Activation by Single Molecule Fluorescence Microscopy
|
biochemistry
|
Green emitting carbon quantum dots (GCQDs) to probe endocytic pathways in cells; for tissue and in vivo bioimaging
|
bioengineering
|
A retrospective molecular investigation of selected pigeon viruses between 2018-2021 in Turkey
|
microbiology
|
Genetic elements orchestrating Lactobacillus crispatus glycogen metabolism in the vagina
|
microbiology
|
Anatomical and Palynological Investigation within flora of Family Asteraceae
|
plant biology
|
A Chalcone Synthase-Like Bacterial Protein Catalyzes Heterocyclic C-Ring Cleavage of Naringenin to Alter Bioactivity Against Nuclear Receptors in Colonic Epithelial Cells
|
microbiology
|
Placental mammal derived microRNAs alter pathways in the endometrial epithelia important for endometrial function.
|
cell biology
|
Proteostatic regulation of caveolins avoids premature oligomerisation and preserves ER homeostasis
|
cell biology
|
Vinculin plays a role in neutrophil stiffening and transit through model capillary segments
|
cell biology
|
Projective LDDMM: Mapping Molecular Digital Pathology with Tissue MRI
|
bioengineering
|
Cryo-electron tomography of the apicomplexan invasion machinery in its native state reveals rigid body motion of the conoid and docked secretory machinery
|
biophysics
|
Saturation mutagenesis of a predicted ancestral Syk-family kinase
|
biochemistry
|
Combined measurements of proteome and cell turnover reveal the influences of tissue context and pathological aging on protein and organelle lifetimes
|
systems biology
|
Immune Checkpoint Activity Regulates Polycystic Kidney Disease Progression
|
immunology
|
Mircubactin B rescues the lethal effect of cell wall biosynthesis mutations in Bacillus subtilis.
|
microbiology
|
Functional Comparison Between Endogenous and Synthetic Notch Systems
|
molecular biology
|
Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes.
|
ecology
|
GNL3 is an evolutionarily-conserved stem cell gene influencing cell proliferation, animal growth, and regeneration in the hydrozoan Hydractinia
|
evolutionary biology
|
Evolutionary analysis of p38 stress activated kinases in unicellular relatives of animals suggests an ancestral function in osmotic stress
|
evolutionary biology
|
A novel de novo FEM1C variant as a potential cause of neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia.
|
genetics
|
Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
|
genomics
|
Direct Visualization of Translesion DNA Synthesis Polymerase IV at the Replisome
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biochemistry
|
Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology
|
bioengineering
|
Mutually exclusive spectral biclustering and its applications in cancer subtyping
|
bioinformatics
|
An evolutionary perspective on the origin, conservation and binding partner acquisition of tankyrases
|
bioinformatics
|
MICOS Complex and Mitochondria Morphology Changes Across Aging in Cardiac Muscle
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biophysics
|
Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability
|
cancer biology
|
Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS
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cancer biology
|
Detection of local growth patterns in longitudinally imaged low-grade gliomas
|
cancer biology
|
Identifying Proteasome 26S Subunit, ATPase (PSMC) Family Genes as the Prognostic Indicators and Therapeutic Targets in Lung Adenocarcinoma
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cancer biology
|
ALDH2 DEFICIENCY INCREASES SUSCEPTIBILITY TO BINGE ALCOHOL-INDUCED GUT LEAKINESS, ENDOTOXEMIA, AND ACUTE LIVER INJURY IN MICE THROUGH THE GUT-LIVER AXIS
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pharmacology and toxicology
|
Regulation of metabolic health by dietary histidine in mice
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physiology
|
Unlocking the strength of inducible promoters in gram-negative bacteria
|
synthetic biology
|
Immune activation state modulates retrieval of infant engrams
|
neuroscience
|
Mechanisms and functions of respiration-driven gamma oscillations in the piriform cortex
|
neuroscience
|
Homogeneous inhibition is optimal for the phase precession of place cells in the CA1 field
|
neuroscience
|
Phylogroup-specific variation shapes pangenome dynamics in Pseudomonas aeruginosa
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microbiology
|
Small-amplitude head oscillations result from a multimodal head stabilization reflex in hawkmoths
|
neuroscience
|
Modified MRI anonymization (de-facing) for improved MEG coregistration
|
molecular biology
|
Altered basal ganglia output during self-restraint
|
neuroscience
|
Advancing antimicrobial resistance monitoring in surface waters with metagenomic and quasimetagenomic methods
|
microbiology
|
EggVio: a user friendly and versatile pipeline for assembly and functional annotation of shallow depth sequenced samples
|
microbiology
|
Intrauterine inflammation leads to some sex and age-specific behavior and molecular differences in mice
|
developmental biology
|
Mapping the risks of China's global coastal development to marine socio-ecological systems
|
ecology
|
The Devil Is In The Details: Landscape Features Are Insufficient To Explain Patterns Of Non-Native Fishes Distribution In North Patagonian Streams
|
ecology
|
Cultural specialization as a double-edged sword: division into specialized guilds might promote cultural complexity at the cost of higher susceptibility to cultural loss
|
evolutionary biology
|
Rare CNVs and phenome-wide profiling: a tale of brain-structural divergence and phenotypical convergence
|
genetics
|
Honey bee functional genomics using symbiont-mediated RNAi
|
genetics
|
Quaternary Ammonium Salt-Modified Isabgol (Psyllium) Scaffold as an Antibacterial Dressing for Improved Wound Healing
|
bioengineering
|
Comparison of dry and wet electrodes for detecting gastrointestinal activity patterns from body surface electrical recordings
|
bioengineering
|
Engineered gene circuits with reinforcement learning allow bacteria to master gameplaying
|
synthetic biology
|
A Computational Theory of Learning Flexible Reward-Seeking Behavior with Place Cells
|
neuroscience
|
The structural basis of long-term potentiation in hippocampal synapses, revealed by EM-imaging of lanthanum-induced synaptic vesicle recycling
|
neuroscience
|
Precise temporal control of GEVI conformations enables the visualization of charge migration in a fluorescent protein resulting in an improved optical response
|
neuroscience
|
The language network reliably 'tracks' naturalistic meaningful non-verbal stimuli
|
neuroscience
|
Toward Interpretable Digital Biomarkers of Walking and Reaching in Parkinson's Disease
|
neuroscience
|
Genome-wide translocation events drive the evolution of Candida africana
|
microbiology
|
Jointly analyzing the association of human milk nutrients with cognition and temperament traits during the first 6 months of life
|
developmental biology
|
Robust analysis of prokaryotic pangenome gene gain and loss rates with Panstripe
|
evolutionary biology
|
Structural variants in the barley gene pool: precision and sensitivity to detect them using short-read sequencing and their association with gene expression and phenotypic variation
|
genomics
|
Direct N-Me Aziridination Reaction Enables Pinpointing C=C Bonds in Lipids with Mass Spectrometry
|
biochemistry
|
DeepTMB: An uncertainty-aware deep calibration of tumor mutational burden with a synthetic tumor-only dataset
|
bioinformatics
|
Loss of the chromatin remodeler, ATRX, promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin receptor binding
|
cancer biology
|
Unlocking the microblogging potential for science and medicine
|
scientific communication and education
|
From the ear flap to the nerve: A complete computer model of the peripheral auditory system
|
neuroscience
|
Decoding reward-curiosity conflict in decision-making from irrational behaviors
|
neuroscience
|
The association between working memory precision and the nonlinear dynamics of frontal and parieto-occipital EEG activity.
|
neuroscience
|
Functional antibodies exhibit light chain coherence
|
immunology
|
First-in-human evaluation of cutaneous innate and adaptive immunomodulation by mosquito bites
|
immunology
|
Similarities and differences in molecular epidemiology of third-generation cephalosporin-resistant Escherichia coli carried by dogs living in urban and nearby rural settings and associated behavioural risk factors
|
microbiology
|
LRRK2 Phosphorylates Neuronal Elav RNA-Binding Proteins to RegulatePhenotypes Relevant to Parkinson's Disease
|
cell biology
|
Identification of genetic markers for the discrimination of Bacillus thuringiensis within the Bacillus cereus group, in the context of foodborne outbreaks
|
bioinformatics
|
Opposite polarity programs regulate asymmetric subsidiary cell divisions in grasses
|
plant biology
|
Ecology and Conservation status of Phoebe hainesiana Brandis: a data deficit timber species of Indo-Myanmar biodiversity hotspot
|
plant biology
|
FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells
|
cell biology
|
Effector-dependent activation and oligomerization of NRC helper NLRs by Rpi-amr3 and Rpi-amr1
|
plant biology
|
The small GTPase ARF3 controls metastasis and invasion modality by regulating N-cadherin levels.
|
cell biology
|
A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
|
cancer biology
|
SOCS3 limits endotoxin-induced endothelial dysfunction by blocking a required autocrine interleukin 6 signal in human umbilical vein endothelial cells
|
cell biology
|
Unravelling the mechanisms of adaptation to high pressure in proteins
|
biophysics
|
The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction
|
biophysics
|
Sensor NLR immune proteins activate oligomerization of their NRC helper
|
plant biology
|
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling
|
microbiology
|
Memory loss at sleep onset
|
neuroscience
|
Isoform-specific O-glycosylation dictates Ebola virus infectivity
|
microbiology
|
The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites
|
microbiology
|
Ancient dental calculus preserves signatures of biofilm succession and inter-individual variation independent of dental pathology
|
microbiology
|
SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating Hes5
|
cell biology
|
Anticodon Table of the Chloroplast Genome and Identification of Putative Quadruplet Anticodons in Chloroplast tRNAs
|
genomics
|
Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
|
genomics
|
The whole blood microbiome of Indonesians reveals that environmental differences shape immune gene expression signatures
|
genomics
|
A Feed-forward Pathway Drives LRRK2 kinaseMembrane Recruitment and Apparent Activation
|
biochemistry
|
Molecular Aggregation Induced Photoacoustics for NIR-II in vivo Imaging
|
biochemistry
|
Functional metagenomic screening in microfluidic droplets identifies a β-glucuronidase in an unprecedented sequence neighbourhood
|
biochemistry
|
Prediction Of The Impact Of Genetic Variability On Drug Sensitivity For Clinically Relevant EGFR Mutations
|
biochemistry
|
Spatial organization of Dectin-1 and TLR2 during synergistic crosstalk revealed by super-resolution imaging
|
biophysics
|
The bHLH transcription factor MpHYPNOS is a critical regulator of gemma dormancy in the liverwort Marchantia polymorpha.
|
plant biology
|
DNA-based detection of Aphanomyces cochlioides in soil and sugar beet plants
|
plant biology
|
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