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HIV-linked gut dysbiosis associates with cytokine production capacity in viral-suppressed people living with HIV
|
microbiology
|
Oral rabies vaccination of dogs - experiences from a field trial in Namibia
|
microbiology
|
Formation of multiple flagella caused by a mutation of the flagellar rotor protein FliM in Vibrio alginolyticus
|
microbiology
|
Structure-based discovery and in vitro validation of selective inhibitors of Chloride Intracellular Channel 4 protein.
|
molecular biology
|
Machine-Learning-Based Olfactometry: Odor Descriptor Clustering Analysis for Olfactory Perception Prediction of Odorant Molecules
|
molecular biology
|
The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization
|
cell biology
|
Paracrine factors of stressed peripheral blood mononuclear cells activate pro-angiogenic and anti- proteolytic processes in whole blood cells and protect the endothelial barrier
|
cell biology
|
Inactivation of histone chaperone HIRA unmasks a link between normal embryonic development of melanoblasts and maintenance of adult melanocyte stem cells
|
developmental biology
|
Interspecific allometric scaling in eDNA production in fishes reflects physiological and surface area allometry
|
ecology
|
Will The Grass Be Greener On The Other Side Of Climate Change?
|
ecology
|
Evolutionary history of metazoan TMEM16 family
|
evolutionary biology
|
A revised perspective on the evolution of troponin I and troponin T in vertebrates
|
evolutionary biology
|
Secondary reversion to sexual monomorphism associated with tissue-specific loss of doublesex expression
|
evolutionary biology
|
A transcriptional program shared across lineages underlies cell differentiation during metazoan development
|
genomics
|
An intrinsic oscillator underlies visual navigation in ants.
|
animal behavior and cognition
|
De novo phytosterol synthesis in animals
|
biochemistry
|
How does data structure impact cell-cell similarity? Evaluating the influence of structural properties on proximity metric performance in single cell RNA-seq data
|
bioinformatics
|
scTagger: Fast and accurate matching of cellular barcodes across short- and long-reads of single-cell RNA-seq experiments
|
bioinformatics
|
METAbolomics data Balancing with Over-sampling Al-gorithms (META-BOA): an online resource for addressing class imbalance
|
bioinformatics
|
Hi-LASSO: High-performance Python and Apache spark packages for feature selection with high-dimensional data
|
bioinformatics
|
Statistical analysis of spatially resolved transcriptomic data by incorporating multi-omics auxiliary information
|
bioinformatics
|
Biomolecular condensates can both accelerate and suppress aggregation of α-synuclein
|
biophysics
|
Crosslinker design determines microtubule network organization by opposing motors
|
biophysics
|
Designing multiphase biomolecular condensates by coevolution of protein mixtures
|
biophysics
|
Improved antiproliferative activity of doxorubicin-loaded calcium phosphate nanoparticles against melanoma cells
|
cancer biology
|
A Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Dysregulation of the Neurovascular Unit Relevant to Brain Inflammation
|
neuroscience
|
CASK and FARP coordinately control pre- and post-synaptic function
|
neuroscience
|
Multisite imaging of neural activity using a genetically encoded calcium sensor in the honey bee Apis mellifera
|
neuroscience
|
Targeting diverse operational regimes in recurrent spiking networks
|
neuroscience
|
Circulating U13 small nucleolar RNA as a candidate biomarker for Huntington's disease
|
neuroscience
|
Enhanced Mirror Neuron Network Activity and Effective Connectivity during Live Interaction
|
neuroscience
|
Phenotypic characterization and analysis of complete genomes of two distinct strains of the proposed species "L. swaminathanii"
|
microbiology
|
Exceptional yield vesicle packaged recombinant protein production from E. coli.
|
molecular biology
|
Spt4 drives cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters
|
molecular biology
|
Nodal signaling establishes a competency window for stochastic cell fate switching
|
developmental biology
|
Pharmacological intervention of the FGF-PTH axis as a potential therapeutic for ciliopathies
|
developmental biology
|
The contribution of mate-choice, couple convergence and confounding to assortative mating
|
genetics
|
Metatranscriptomic comparison of viromes in endemic and introduced passerines in New Zealand
|
bioinformatics
|
CONCERT: Genome-wide prediction of sequence elements that modulate DNA replication timing
|
bioinformatics
|
Archaeal bundling pili of Pyrobaculum calidifontis reveal similarities between archaeal and bacterial biofilms
|
biophysics
|
Active mechanics of sea star oocytes
|
biophysics
|
Membrane tension spatially organizes lysosomal exocytosis
|
biophysics
|
ACSS2 Regulates HIF-2α Degradation through the E3-Ubiquitin Ligase MUL1 in Clear Cell Renal Cell Carcinoma
|
cancer biology
|
Genomic and transcriptomic landscape of advanced renal cell cancer to individualize treatment strategy
|
cancer biology
|
A revised phylogenetic classification for Viola (Violaceae)
|
plant biology
|
Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment
|
systems biology
|
Chemogenetic disconnection between the orbitofrontal cortex and the rostromedial caudate nucleus disrupts motivational control of goal-directed action
|
neuroscience
|
Organization of the corticotropin-releasing hormone and corticotropin-releasing hormone-binding protein systems in the central nervous system of the sea lamprey Petromyzon marinus
|
neuroscience
|
Impaired immune response drives age-dependent severity of COVID-19
|
immunology
|
An Efficient Approach for SARS-CoV-2 Monoclonal Antibody Production via Modified mRNA-LNP Immunization
|
immunology
|
A highly sensitive strand-specific multiplex RT-qPCR assay for quantitation of Zika virus replication
|
microbiology
|
Intrinsic furin-mediated cleavability of the spike S1/S2 site from SARS-CoV-2 variant B.1.529 (Omicron)
|
microbiology
|
Integrated optical device for Structured Illumination Microscopy
|
cell biology
|
Crop management shapes the diversity and activity of DNA and RNA viruses in the rhizosphere
|
ecology
|
The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron
|
biochemistry
|
SARS-CoV-2 spike variants differ in their allosteric response to linoleic acid
|
biochemistry
|
High-Throughput Global Phosphoproteomic Profiling Using Phospho Heavy-Labeled-Spiketide FAIMS Stepped-CV DDA (pHASED)
|
biochemistry
|
The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells
|
cancer biology
|
Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer's Dementia
|
neuroscience
|
Synapses learn to utilize pre-synaptic noise for the prediction of postsynaptic dynamics
|
neuroscience
|
Protein preference and elevated plasma FGF21 induced by dietary protein restriction is similar in both male and female mice
|
neuroscience
|
MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle
|
cell biology
|
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life history stages
|
evolutionary biology
|
SMURF: embedding single-cell RNA-seq data with matrix factorization preserving selfconsistency
|
bioinformatics
|
Identifying the best approximating model in Bayesian phylogenetics: Bayes factors, cross-validation or wAIC?
|
bioinformatics
|
IL-17A controls CNS autoimmunity by regulating gut microbiota and inducing regulatory T cells
|
immunology
|
Run-on sequencing reveals nascent transcriptomics of the human microbiome
|
microbiology
|
Circular mRNA encoded PROTAC (RiboPROTAC) as a new platform for the degradation of intracellular therapeutic targets
|
molecular biology
|
Adenine base editing is an efficient approach to restore function in FA patient cells without double-stranded DNA breaks
|
molecular biology
|
Quantifying the fraction of new mutations that are recessive lethal
|
evolutionary biology
|
Genetic dissection of the pluripotent proteome through multi-omics data integration
|
genetics
|
The molecular consequences of androgen activity in the human breast
|
genomics
|
A phased chromosome-level genome and full mitochondrial sequence for the dikaryotic myrtle rust pathogen, Austropuccinia psidii
|
genomics
|
Peroxisomal ATPase ATAD1 acts in quality control of the protein import machinery
|
biochemistry
|
Simple within-stride changes in treadmill speed can drive selective changes in human gait symmetry
|
bioengineering
|
Detection and discrimination of single nucleotide polymorphisms by quantification of CRISPR-Cas catalytic efficiency
|
bioengineering
|
Prediction of Kinase-Substrate Associations Using The Functional Landscape of Kinases and Phosphorylation Sites
|
bioinformatics
|
Multiple modes of substrate hydrolysis-induced covalent modification of strigolactone receptors
|
biophysics
|
cMYC protein interactions and chromatin association in NUT carcinoma
|
cancer biology
|
Engineered extracellular matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids
|
cancer biology
|
Polarly localized WPR proteins interact with PAN receptors and the actin cytoskeleton during maize stomatal development
|
plant biology
|
The effect of sleep continuity disruption on multimodal emotion processing and regulation: a laboratory-based, randomized, controlled experiment in good sleepers
|
neuroscience
|
Ventral Hippocampal Infusions of C20:0 Ceramide Stimulate Microglia and Induce Anhedonia-like Behavior in Female and Male Rats
|
neuroscience
|
Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice.
|
neuroscience
|
Individual prediction tendencies facilitate cortical speech tracking
|
neuroscience
|
Neural connectivity molecules best identify the heterogeneous clock and dopaminergic cell types in the Drosophila adult brain
|
neuroscience
|
Dual RNA-seq reveals a type 6 secretion system-dependent blockage of TNF-α signaling and BicA as a Burkholderia pseudomallei virulence factor important during gastrointestinal infection
|
microbiology
|
Locomotion control during curb descent: Bilateral ground reaction variables covary consistently during the double support phase regardless of future foot placement constraints
|
bioengineering
|
Implications for food safety of the size and location of fragments of lead shotgun pellets embedded in hunted carcasses of small game animals intended for human consumption
|
pharmacology and toxicology
|
Metabolic size scaling reflects growth performance effects on age-size relationships in mussels (Mytilus galloprovincialis).
|
physiology
|
Characterization of human immunodeficiency virus (HIV-1) envelope glycoprotein variants selected for resistance to a CD4-mimetic compound
|
microbiology
|
Isotopic reconstruction of the subsistence strategy for a Central Italian Bronze Age community (Pastena cave, 2nd millennium BCE).
|
evolutionary biology
|
A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence
|
genomics
|
A method to enrich polypeptidyl-tRNAs to capture snapshots of translation in the cell
|
biochemistry
|
A revisit to universal single-copy genes in bacterial genomes
|
bioinformatics
|
Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade and the role of insertions and extensions in diversification
|
bioinformatics
|
GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information.
|
bioinformatics
|
Self-consistent solution to the Flory-Huggins model and applications in protein liquid-liquid phase separation
|
biophysics
|
TFIIF interacts with the Topoisomerase VI complex and selectively controls the expression of genes encoding PPR proteins involved in organellar RNA editing in Arabidopsis.
|
plant biology
|
A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics
|
immunology
|
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