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Lagrange-NG: The next generation of Lagrange
bioinformatics
Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies.
cancer biology
Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression
cancer biology
Restriction of dietary fat, but not carbohydrate, alters brain reward circuitry in adults with obesity
neuroscience
Cortical facilitation of somatosensory inputs using gravity-related tactile information in patients with bilateral vestibular loss
neuroscience
Microglial inflammatory activation paradoxically improves glucose tolerance during diet-induced obesity
neuroscience
Prolonged dexamethasone exposure enhances zebrafish lateral-line regeneration but disrupts mitochondrial homeostasis and hair cell function
neuroscience
TubULAR: Tracking deformations of dynamic tissues and interfaces in 3D
developmental biology
The Global Register of Introduced and Invasive Species: Country Compendium
ecology
DNA metabarcoding reveals the threat of rapidly expanding barred owl populations to native wildlife in western North America
ecology
Evaluating drivers of spatiotemporal individual condition of a bottom-associated marine fish
ecology
Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
genetics
Commercial ChIP-Seq library preparation kits performed differently for different classes of protein targets
bioinformatics
moRphology - dEep Learning Imaging Cells (RELIC) - to Differentiate Between Normal and Pathological Kidney Exfoliated Cells
bioinformatics
Chaotic dynamics in spatially distributed neuronal networks generate population-wide shared variability
neuroscience
Transmission of Cervid Prions to Humanized Mice Demonstrates the Zoonotic Potential of CWD
neuroscience
Activation of IP10/CXCR3 signaling with highly coincidental with PrPSc deposit in the brains of scrapie infected mice
neuroscience
Evolution of influenza A virus hemagglutinin H1 and H3 across host species
evolutionary biology
A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset
bioinformatics
From motif to function:Inferring the functions of long zinc finger proteins through combinatorial selection
bioinformatics
A neurocomputational theory of action regulation predicts motor behavior in neurotypical individuals and patients with Parkinsons disease
neuroscience
Listeria monocytogenes Infection Alters Extracellular Vesicles Produced by Trophoblast Stem Cells to Confer a Pro-Inflammatory State
immunology
First detection of Leptospira santarosai in the reproductive track of a boar: a potential threat to swine production and public health
microbiology
Genomic profiling of climate adaptation in Aedes aegypti along an altitudinal gradient in Nepal indicates non-gradual expansion of the disease vector
genomics
Functional characterization of TANGLED1 interaction with PHRAGMOPLAST ORIENTING KINESIN1 during mitosis in Arabidopsis
plant biology
Release of VAMP5-positive extracellular vesicles from specialized domains of retinal Müller cells in vivo
neuroscience
Two interdigitated fine-scale channels for encoding motion and stereopsis within the human magnocellular stream
neuroscience
Functional Specialization of Parallel Distributed Networks Revealed by Analysis of Trial-to-Trial Variation in Processing Demands
neuroscience
Gut microbiota analysis of the western honeybee (Apis mellifera L.) infested with the mite Varroa destructor reveals altered bacterial and archaeal community
microbiology
The structure and evolutionary diversity of the fungal E3-binding protein
molecular biology
BIN2 phosphorylates the Thr280 of CO to restrict its function in promoting Arabidopsis flowering
molecular biology
Environmental DNA persistence and fish detection in captive sponges
ecology
Speciation without gene-flow in hybridizing deer
evolutionary biology
TAF4b Transcriptional Regulation During Cellular Quiescence of Developing Prospermatogonia
genetics
Supercoiling-mediated feedback rapidly couples and tunes transcription
synthetic biology
Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV Pathogen Box
microbiology
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data
genetics
Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice
immunology
Low-dose bivalent mRNA vaccine is highly effective against different SARS-CoV-2 variants in a transgenic mouse model
immunology
Compellingly high SARS-CoV-2 susceptibility of Golden Syrian hamsters suggests multiple zoonotic infections of pet hamsters during the COVID-19 pandemic
microbiology
Emergence of new subgenomic mRNAs in SARS-CoV-2
microbiology
Uncovering the structural flexibility of SARS-CoV-2 glycoprotein spike variants
biochemistry
Matrix stiffness regulates Notch signaling activity in endothelial cells
cell biology
Src42A is required for E-cadherin dynamics at cell junctions during Drosophila axis elongation
developmental biology
A benchmark of Hi-C scaffolders using reference genomes and de novo assemblies
genomics
G6PD Inhibition Sensitizes Ovarian Cancer Cells to Oxidative Stress in the Metastatic Omental Microenvironment
cancer biology
Hybridization In The Late Pleistocene: Merging Morphological And Genetic Evidence
paleontology
Spatiotemporal Profiling of Seed-Associated Microbes of an Aquatic, Intermediate Recalcitrant Species, Zizania palustris L. and the Impact of Anti-Microbial Seed Treatments
plant biology
Vision-dependent and -independent molecular maturation of mouse retinal ganglion cells
neuroscience
Glutamatergic projections from ventral hippocampus to nucleus accumbens cholinergic neurons are altered in a mouse model of depression
neuroscience
Myeloid-Derived Suppressor Cells are relevant factors to predict the severity of multiple sclerosis
neuroscience
Macrophages undergo necroptosis during severe influenza A infection and contribute to virus-associated cytokine storm
immunology
lsaBGC provides a comprehensive framework for evolutionary analysis of biosynthetic gene clusters within focal taxa
microbiology
Phylogenetic and phenotypic analysis of five subgroups of Ralstonia solanacearum phylotype IIB sequevar 4 reveals that the "not pathogenic to banana (NPB)" ecotype is polyphyletic.
microbiology
A remarkable expansion of oligopeptide transporter genes in rust fungi (Pucciniales) suggests a specialization in nutrients acquisition for obligate biotrophy
microbiology
Vegetation formation in Staphylococcus aureus endocarditis inversely correlates with RNAIII and sarA expression in invasive clonal complex 5 (CC5) isolates
microbiology
The association of ubiquitin-associated protein 2-like and Ras-GTP-activating protein SH3 domain binding protein 1 mediated by small nucleolar RNA is essential for stress granule formation
cell biology
JiangShi: a widely distributed Mucin-like protein essential for Drosophila development
developmental biology
Chromosome-level genome assembly for the Aldabra giant tortoise enables insights into the genetic health of a threatened population
genomics
Single-cell mapping of tumor heterogeneity in pediatric rhabdomyosarcoma reveals developmental signatures with therapeutic relevance
cancer biology
Evaluation of sex differences in laser-induced choroidal neovascularization severity, phenotype and disease progression
cell biology
Investigating the antioxidant effects of Aloe vera: Possible role in regulating lipid profile and liver function in high fat and fructose diet (HFFD) fed mice.
biochemistry
Endogenous production of hyaluronan, PRG4, and cytokines is sensitive to cyclic loading in synoviocytes
bioengineering
Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans
microbiology
A new in vitro checkerboard-parasite reduction ratio interaction assay for early de-risk of clinical development of antimalarial combinations
microbiology
Global and gene-specific translational regulation in Escherichia coli across different conditions
genomics
Importance of Mobile Genetic Element Immunity in Numerically Abundant Trichodesmium Clades
microbiology
'Ripple effects' of urban environmental characteristics on cognitive processes in Eurasian red squirrels.
animal behavior and cognition
Associations between physical activity and cognitive dysfunction in older companion dogs: Results from the Dog Aging Project
animal behavior and cognition
Making Biomedical Research Software FAIR: Actionable Step-by-step Guidelines with a User-support Tool
scientific communication and education
Adaptive plasticity in the healthy reading network investigated through combined neurostimulation and neuroimaging
neuroscience
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition
cell biology
Multiple routes of adaptation to high levels of CIN and aneuploidy in budding yeast
cell biology
In situ polyadenylation enables spatial mapping of the total transcriptome
genomics
A Hybrid Method for Ultrasound-Based Tracking of Skeletal Muscle Architecture
bioengineering
An anaphase switch in astral microtubule dynamics specifically requires the APC/C-Cdc20-dependent degradation of the mitotic cyclin Clb4
cell biology
Ubiquitination occurs in the mitochondrial matrix byeclipsed targeted components of the ubiquitin machinery
cell biology
Replicative ageing perturbs the metabolic signature of murine C2C12 skeletal myotubes
cell biology
p38 MAPK Signaling Enhances Reovirus Replication by Facilitating Efficient Virus Entry, Virus Capsid Uncoating and Post-Uncoating Steps.
cell biology
Statistical learning of distractor co-occurrences facilitates visual search
neuroscience
Lung spatial profiling reveals a T cell signature in COPD patients with fatal SARS-CoV-2 infection
immunology
Different conformations of EGF-induced receptor dimers involved in signaling and internalization
molecular biology
Omics of an enigmatic marine amoeba uncovers unprecedented giant viruses gene trafficking and provides insights into its complex life cycle
genomics
Strategies for enriching and characterizing proteins with inhibitory properties on the yeast surface
bioengineering
Is single nucleus ATAC-seq accessibility a qualitative or quantitative measurement?
bioinformatics
Persistent Memory as an Effective Alternative to Random Access Memory in Metagenome Assembly
bioinformatics
Fast, accurate antibody structure prediction from deep learning on massive set of natural antibodies
bioinformatics
Scalable and model-free detection of spatial patterns and colocalization
bioinformatics
Bacillus subtilis Biofilms in the Presence of Chlorhexidine - a Computational Approach to Morphology and Growth Kinetics Analysis
bioinformatics
BiocMAP: A Bioconductor-friendly, GPU-Accelerated Pipeline for Bisulfite-Sequencing Data
bioinformatics
Full geroprotection from brief rapamycin treatment by persistently increased intestinal autophagy
physiology
Slowing of Frontocentral Beta Oscillations in Atypical Parkinsonism
neuroscience
Brain network integration, flexibility and quasicyclicity during task and rest.
neuroscience
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
immunology
Candidatus Nealsonbacteria (OD1) in a methanogenic benzene-degrading enrichment culture is likely an ectosymbiotic biomass recycler
microbiology
A chemically inducible muscle ablation system for zebrafish
developmental biology
Mesostats - A multiplexed, low-cost, do-it-yourself continuous culturing system for experimental evolution of mesocosms
evolutionary biology
Linking cells across single-cell modalities by synergistic matching of neighborhood structure
genomics
Genome-wide identification and expression analysis of bHLH transcription factors reveal their putative regulatory effects on petal nectar spur development in Aquilegia
plant biology
Rapid learning of predictive maps with STDP and theta phase precession
neuroscience