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An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa
microbiology
The baseline immunological and hygienic status of pigs impact disease severity of African swine fever
microbiology
Incorporating selection pressures into risk predictions of chemical resistance evolution in pest organisms
evolutionary biology
Whole-Genome Profiling of Ethyl Methanesulfonate Mutagenesis in Tomato
plant biology
Functional Recovery from Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts is Dependent on Neurite Outgrowth
neuroscience
Peer presence elicits task-independent changes within and beyond the mentalizing network across children and adults
neuroscience
Mechanism of dopamine traveling waves in the striatum: theory and experiment
neuroscience
Analog of Kynurenic Acid Decreases Tau Pathology by Modulating Astrogliosis in Rat Model for Tauopathy.
neuroscience
Cross-modal alterations of Alpha Activity do not reflect inhibition of early sensory processing: A frequency tagging study
neuroscience
Clonal spreading of tumor-infiltrating T cells underlies the robust antitumor immune responses
immunology
Hidden Talents: Silent Gene Clusters Encoding Magnetic Organelle Biosynthesis in a Non-Magnetotactic Phototrophic Bacterium
microbiology
Effects of abiotic environment on invertebrate herbivory depend on plant community context in a montane grassland
ecology
Spatial and social structure of rewilded laboratory mice
animal behavior and cognition
Predicting A/B compartments from histone modifications using deep learning
bioinformatics
fastman: A fast algorithm for visualizing GWAS results using Manhattan and Q-Q plots
bioinformatics
An objective criterion to evaluate sequence-similarity networks helps in dividing the protein family sequence space
bioinformatics
Finding heterogeneously methylated genomicregions using ONT reads
bioinformatics
ISM-FLUX: single-step MINFLUX with an array detector
biophysics
Low Level Whole-Brain Radiation Enhances Theranostic Potential Of Single Domain Antibody Fragments For HER2-Positive Brain Metastases
cancer biology
helixCAM: A Platform for Programmable Cellular Assembly in Bacteria and Human Cells
synthetic biology
More than just hitchhikers: a survey of bacterial communities associated with diatoms originating from marine reptiles
microbiology
Wolbachia inhibits ovarian formation and increases blood avidity in female Aedes aegypti-a novel time-specific reproductive alteration
microbiology
Gene regulation by synergism between mRNA decay and gene transcription
molecular biology
Deciphering the roadmap of in vivo reprogramming towards pluripotency
developmental biology
Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development
developmental biology
Change in prey genotype frequency rescues predator from extinction
evolutionary biology
MALE-MALE SOCIAL BONDING, COALITIONARY SUPPORT AND REPRODUCTIVE SUCCESS IN WILD GUINEA BABOONS
animal behavior and cognition
Sex-dependent transcriptional control of cardiac electrophysiology by histone acetylation modifiers based on the GTEx database
bioengineering
CPGL: Prediction of compound-protein interaction by integrating graph attention network with long short-term memory neural network
bioinformatics
scAEGAN: Unification of Single-Cell Genomics Data by Adversarial Learning of Latent Space Correspondences
bioinformatics
SiCoDEA: a simple, fast and complete app for analyzing the effect of individual drugs and their combinations
bioinformatics
Estimation of microtubule-generated forces using a DNA origami nanospring
biophysics
Serotonin, Etonogestrel and breathing activity in murine Congenital Central Hypoventilation Syndrome
physiology
Autophagy modulates apical growth and development in the moss Physcomitrium patens
plant biology
Extensive de novo activity stabilizes epigenetic inheritance of CG methylation in Arabidopsis transposons
genetics
Modular safe-harbor Transgene Insertion (MosTI) for targeted single-copy and extrachromosomal array integration in C. elegans.
genetics
3D printed SAXS chamber for controlled in-situ dialysis and optical characterization
biophysics
Vγ9Vδ2 T cells are potent inhibitors of SARS-CoV-2 replication and exert effector phenotypes in COVID-19 patients
immunology
Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses using gene expression profiles of chemical and genetic perturbations
genomics
Redox regulation of the SARS-CoV-2 main protease provides new opportunities for drug design
biochemistry
Persistent cross-species SARS-CoV-2 variant infectivity predicted via comparative molecular dynamics simulation
bioinformatics
Read2Tree: scalable and accurate phylogenetic trees from raw reads
bioinformatics
An approximate line attractor in the hypothalamus that encodes an aggressive internal state
neuroscience
An intranasal nanoparticle STING agonist has broad protective immunity against respiratory viruses and variants
immunology
BCG vaccination of Diversity Outbred mice induces cross-reactive antibodies to SARS-CoV-2 spike protein
immunology
The Spike protein of SARS-CoV-2 impairs lipid metabolism and increases susceptibility to lipotoxicity: implication for a role of Nrf2
cell biology
Phylogeny and Metadata Network Database for Epidemiologic Surveillance
evolutionary biology
Tracking the circulating SARS-CoV-2 variants in Turkey: Complete genome sequencing and molecular characterization of 1000 SARS-CoV-2 samples
genomics
COVID-19 Infection and Transmission Includes Complex Sequence Diversity
genomics
Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
biochemistry
Predicting gene expression from cell morphology in human induced pluripotent stem cells
bioengineering
Nucleosome sliding by the Chd1 chromatin remodeler relies on theintegrity of the DNA duplex
biophysics
Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators
biophysics
Microbial mutualism generates multistable and oscillatory growth dynamics
systems biology
Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via epigenetic regulation of key regenerative pathways
neuroscience
Enhancing Polysaccharide Immunity through Intranasal Immunizations
immunology
The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
immunology
Intercellular collectivity is governed by enzyme secretion strategies in marine polysaccharide degrading bacteria
microbiology
Functional characterization of bacterial isolates from dye decolorizing consortia and a step-up metabolic engineering based on NADH-regeneration
microbiology
Nonstructural protein 1 (nsp1) widespread RNA decay phenotype varies among Coronaviruses
microbiology
eIf2α-regulated translation modulates the early adhesion of mesenchymal-like cells
cell biology
Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells Running title: Cystin deficiency reduces FPC levels through enhanced autophagic degradation.
cell biology
Inducing Specific Chromosome Mis-Segregation in Human Cells
cell biology
Why resource dynamics matter in the optimization of microbial communities
ecology
Do Neotropical adult dobsonflies (Megaloptera, Corydalidae) feed on solid material in the nature? Information from a gut content study
ecology
NIPBL and WAPL balance cohesin activity to regulate chromatin folding and gene expression
genetics
High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course
genomics
Molecular diversity and phenotypic pleiotropy of genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their impacts on pathophysiology of Modern Humans.
genomics
Clearing of ribosome collisions by the ribosome quality control trigger complex RQT
biochemistry
Tissue Specific Knockout of the Cardiolipin Transacylase Enzyme TAFAZZIN in Both Liver and Pancreatic Beta Cells Protects Mice From Diet-Induced Obesity
biochemistry
Engineering and characterization of a long half-life relaxin receptor RXFP1 agonist
pharmacology and toxicology
The mitogen-activated protein kinase kinase kinase, ILK5, regulates plant purinergic receptor-mediated, innate immunity
plant biology
Vitis vinifera plants edited in DMR6 genes show improved resistance to downy mildew.
plant biology
Transcriptome profiling of the dorsomedial prefrontal cortex in suicide victims
neuroscience
An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis
immunology
T cell Aryl Hydrocarbon Receptor Activity Tunes the Gut Microenvironment to Sustain Autoimmunity.
immunology
Canal number and configuration are predictors of external root morphology
evolutionary biology
Development of transformation for genome editing of an emerging model organism
genetics
High resolution shotgun metagenomics: the more data, the better?
bioinformatics
Bats as ecosystem engineers in iron ore caves in the Carajas National Forest, Brazilian Amazonia
ecology
Motor outcomes congruent with intentions may sharpen metacognitive representations
neuroscience
Disruption of anterior temporal lobe reduces distortions in memory from category knowledge
neuroscience
Language and the cerebellum: structural connectivity to the eloquent brain
neuroscience
Binding of the peptide deformylase on the ribosome surface modulates the structure and dynamics of the exit tunnel interior
biophysics
C. elegans Sine oculis/SIX-type homeobox genes act as homeotic switches to define neuronal subtype identities
neuroscience
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB
molecular biology
A motor-based approach to induce chromosome-specific mis-segregations in human cells
cell biology
Sorting of secretory proteins at the trans-Golgi network by TGN46
cell biology
The stoichiometric interaction model for mesoscopic molecular dynamics simulations of liquid-liquid phase separation
biophysics
Weak tension accelerates hybridization and dehybridization of short oligonucleotides
biophysics
A genotoxic antibody drug conjugate targeting CD276/B7H3 demonstrates efficacy across multiple biomarker defined classes of treatment refractory metastatic prostate cancer
cancer biology
mTORC1 activity is essential for disease progression in chronic lymphocytic leukemia
cancer biology
Statistical evaluation of metaproteomics and 16s rRNA amplicon sequencing techniques for the study of the gut microbiota establishment of infants with cystic fibrosis
microbiology
SUMOylation controls the rapid transcriptional reprogramming induced by anthracyclines in Acute Myeloid Leukemias
molecular biology
Nanostructure of the desmosomal plaque
cell biology
Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Induces Diffuse Microglia Activation
cancer biology
pH as an eco-evolutionary driver of priority effects
ecology
Functional characterization of putative ecdysone transporters in lepidopteran pests
genetics
The estrogen receptor α cistrome in human endometrium and epithelial organoids
genomics
Dynamics and Energetics of Bottlenose Dolphins (Tursiops truncatus) Fluke-and-Glide Gait
animal behavior and cognition