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Next generation sequencing analysis of gastric cancer identifies the leukemia inhibitory factor receptor (LIFR) as a driving factor in gastric cancer progression and as a predictor of poor prognosis
|
cancer biology
|
A QuantCrit investigation of society's educational debts due to racism, sexism, and classism in biology student learning
|
scientific communication and education
|
A unique epigenomic landscape defines CD8+ tissue-resident memory T cells
|
immunology
|
Identification of viral dose and administration time in simulated phage therapy occurrences
|
microbiology
|
Molecular insights into the effect of alkanediols on FUS liquid-liquid phase separation
|
biochemistry
|
Skull and scalp segmentation in neonatal cerebral MRI using subject-specific probability models
|
bioengineering
|
Systematic benchmarking of all-in-one microbial SNP calling pipelines
|
bioinformatics
|
Automated systematic evaluation of cryo-EM specimens with SmartScope
|
biophysics
|
An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
|
cancer biology
|
M2-polarized macrophages control LSC fate by enhancing stemness, homing, immune evasion and metabolic reprogramming
|
cancer biology
|
Nav1.1 in mammalian sensory neurons is required for normal motor behaviors
|
neuroscience
|
Probabilistic Tracking U-fiber on the Superficial White Matter Surface
|
neuroscience
|
Bacterial association with metals enables in vivo tracking of microbiota using magnetic resonance imaging
|
microbiology
|
Acinetobacter baumannii and cefiderocol between cidality and adaptability
|
microbiology
|
Polyimidazolium protects against an invasive clinical isolate of Salmonella Typhimurium
|
microbiology
|
Serine Deamination as a New Acid Resistance Mechanism in Escherichia coli
|
microbiology
|
Development of recombinant monoclonal antibodies targeting conserved VlsE epitopes in Lyme disease pathogens
|
microbiology
|
Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion
|
cell biology
|
Incorporating uniparental markers and demographic information in kinship analysis
|
ecology
|
Depth normalization for single-cell genomics count data
|
bioinformatics
|
The dependence of EGFR oligomerization on environment and structure: A camera-based N&B study
|
biophysics
|
SWEET13 transport of sucrose, but not gibberellin, restores male fertility in Arabidopsis sweet13;14
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plant biology
|
Transcriptional fluctuations govern the serum dependent cell cycle duration heterogeneities in Mammalian cells
|
systems biology
|
Obesity medication lorcaserin requires brainstem GLP-1 neurons to reduce food intake in mice
|
neuroscience
|
The LC3B FRET biosensor monitors the modes of action of ATG4B during autophagy in living cells
|
cell biology
|
Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo.
|
cell biology
|
Depth and evenness of sequence coverage are associated with assembly quality, genome structure, and choice of sequencing platform in archived plastid genomes
|
genomics
|
Plasmid overlap and evolution between Enterobacterales isolates from bloodstream infections and non-human compartments
|
genomics
|
Reinforcement waves as a mechanism for discontinuous learning
|
animal behavior and cognition
|
Crystal structure and biochemical analysis suggest that YjoB ATPase is a substrate-specific molecular chaperone
|
biochemistry
|
Nucleation and stability of branched versus linear Arp2/3-generated actin filaments
|
biochemistry
|
Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin
|
biochemistry
|
ReCSAI Recursive compressed sensing artificial intelligence for confocal lifetime localization microscopy
|
bioinformatics
|
Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel
|
biophysics
|
Barley powdery mildew effector CSEP0162 targets multivesicular body-associated MON1 important for immunity
|
plant biology
|
Compartment-driven imprinting of intestinal CD4 (regulatory) T cells in inflammatory bowel disease and homeostasis
|
immunology
|
Suppression of tumor/host intrinsic CMTM6 drives anti-tumor cytotoxicity in a PD-L1 independent manner
|
immunology
|
Orai3 and Orai1 are essential for CRAC channel function and metabolic reprogramming in B cells
|
immunology
|
Understanding the role of c-di-AMP signaling in determining antibiotic tolerance in Mycobacterium smegmatis: generation of resistant mutants and regrowth of persisters
|
microbiology
|
A new microbiological weapon against lepidopteran pests
|
microbiology
|
Metalation calculators for E. coli strain JM109 (DE3): Aerobic, anaerobic and hydrogen peroxide exposed cells cultured in LB media
|
cell biology
|
Fluorescence fluctuation based super resolution microscopy, basic concepts for an easy start.
|
bioinformatics
|
A glutamine-based single α-helix scaffold to target globular proteins
|
biophysics
|
Nanoscale prognosis of colorectal cancer metastasis from AFM image processing of histological sections
|
cancer biology
|
Sinking a giant: quantitative macroevolutionary comparative methods debunk qualitative assumptions
|
paleontology
|
Density-Dependent Color Scanning Electron Microscopy (DDC-SEM) for calcified tissue and pathological calcification.
|
pathology
|
Piezo buffers mechanical stress via modulation of intracellular Ca2+ handling in the Drosophila heart
|
physiology
|
Allocation of visuospatial attention indexes evidence accumulation for reach decisions
|
neuroscience
|
Conserved population dynamics in the cerebro-cerebellar system between waking and sleep
|
neuroscience
|
Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson's patients
|
neuroscience
|
A novel mouse model of postpartum depression and the neurobiological effects of fast-acting antidepressant treatments
|
neuroscience
|
Endogenous retroviruses promote prion-like spreading of proteopathic seeds
|
neuroscience
|
Unraveling the hidden diversity of endogenous bornavirus-like elements derived from ancient orthobornaviral X and P genes in mammalian genomes
|
microbiology
|
Vertical gradients in physiological function and resource allocation of white spruce diverge at the northern- and southern-most range extremes
|
ecology
|
Phasing of de novo mutations using a scaled-up multiple amplicon long-read sequencing approach
|
genomics
|
Quantification of hypoxic regions distant from occlusions in cerebral penetrating arteriole trees
|
bioengineering
|
SimBu: Bias-aware simulation of bulk RNA-seq data with variable cell type composition
|
bioinformatics
|
Multiple instance learning to predict immune checkpoint blockade efficacy using neoantigen candidates
|
bioinformatics
|
Spatio-temporal diversity of dietary preferences and stress sensibilities of early and middle Miocene Rhinocerotidae from Eurasia: impact of climate changes
|
paleontology
|
A new device for continuous non-invasive measurements of leaf water content using NIR-transmission allowing dynamic tracking of water budgets
|
plant biology
|
Heart Rate Variability Covaries with Amygdala Functional Connectivity During Voluntary Emotion Regulation
|
neuroscience
|
Single neurons and networks in the claustrum integrate input from widespread cortical sources
|
neuroscience
|
The vectoring competence of the mite Varroa destructor for Deformed wing virus of honey bees is highly dynamic and affects survival of the mite.
|
microbiology
|
ACE2 nanoparticles prevent cell entry of SARS-CoV-2
|
cell biology
|
Intracellular connections between basal bodies promote the coordinated behavior of motile cilia
|
cell biology
|
A Saccharomyces cerevisiae Model for Overexpression of Ntg1 a Base Excision DNA Repair Protein Reveals Novel Genetic Interactions
|
genetics
|
Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice
|
cancer biology
|
Knockout of mitogen-activated protein kinase 3 causes barley root resistance against Fusarium graminearum.
|
plant biology
|
Modelling the within-host spread of SARS-CoV-2 infection, and the subsequent immune response, using a hybrid, multiscale, individual-based model. Part I: Macrophages.
|
systems biology
|
Antigenicity is preserved with fixative solutions used in human gross anatomy: A mice brain immunohistochemistry study.
|
neuroscience
|
Immunological findings in a group of individuals who were non-responders to standard two-dose SARS-CoV-2 vaccines
|
immunology
|
ORF6 protein of SARS-CoV-2 inhibits TRIM25 mediated RIG-I ubiquitination to mitigate type I IFN induction.
|
microbiology
|
Reaction Conditions Promoting the Specific Detection of SARS-CoV-2 NendoU Enzymatic Activity
|
microbiology
|
GDF15 and ACE2 stratify COVID19 patients according to severity while ACE2 mutations increase infection susceptibility.
|
molecular biology
|
Notch signaling functions in non-canonical juxtacrine manner in platelets to amplify thrombogenicity
|
cell biology
|
Allelic gene polymorphisms suspected to diversify the individual early metabolic response upon influenza H3N2 and SARS-CoV-2 infections
|
cell biology
|
Interrogating the Precancerous Evolution of Pathway Dysfunction in Lung Squamous Cell Carcinoma Using XTABLE
|
bioinformatics
|
Insulin receptors in pancreatic acinar cells contribute to KrasG12D-driven cancer initiation in the context of diet-induced obesity
|
cancer biology
|
Heterologous expression of a lycophyte protein enhances angiosperm seedling vigor
|
plant biology
|
Expansion of information in scientific research papers
|
scientific communication and education
|
SARS-CoV-2 evolution and patient immunological history shape the breadth and potency of antibody-mediated immunity
|
microbiology
|
DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-cell Heterogeneity
|
developmental biology
|
Draft genome of six Cuban Anolis lizards and insights into genetic changes during the diversification
|
genomics
|
Mechanism of the cadherin-catenin F-actin catch bond interaction
|
biophysics
|
Ongoing Replication Stress Response and New Clonal T Cell Development Discriminate Between Liver and Lung Recurrence Sites and Patient Outcomes in Pancreatic Ductal Adenocarcinoma
|
cancer biology
|
Chromosomal position of ribosomal protein genes impacts long term evolution of Vibrio cholerae.
|
microbiology
|
Characteristics of intestinal microflora and dysbiosis in relation to the disease duration in patients with Meniere's disease
|
microbiology
|
Local adaptation of Aedes aegypti mosquitoes to Wolbachia-induced fitness costs
|
evolutionary biology
|
Structure of C. elegans TMC-1 complex illuminates auditory mechanosensory transduction
|
biochemistry
|
A curated data resource of 214K metagenomes for characterization of the global resistome
|
bioinformatics
|
Effects of anti-fibrotic standard of care drugs on senescent human lung fibroblasts
|
pharmacology and toxicology
|
The peptide GOLVEN10 controls nodule and lateral root organogenesis and positioning along the longitudinal root axis
|
plant biology
|
Insulin docking within the open hemichannel of connexin 43 may reduce risk of amyotrophic lateral sclerosis
|
neuroscience
|
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 to drive osteoarthritis
|
cell biology
|
Messenger-RNA Modification Standards and Machine Learning Models Facilitate Absolute Site-Specific Pseudouridine Quantification
|
genomics
|
Atomic protein structure refinement using all-atom graph representations and SE(3)-equivariant graph neural networks
|
bioinformatics
|
Metagenomic analysis of coprolites from three Late Pleistocene megaherbivores from the Southwestern United States.
|
paleontology
|
Highly efficient healing of critical sized articular cartilage defect in situ using a chemically nucleoside-modified mRNA-enhanced cell therapy
|
synthetic biology
|
Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Towards an Annulus Fibrosus-like Cell Phenotype
|
cell biology
|
Modulation of Tau Tubulin Kinases (TTBK1 and TTBK2) Impacts Ciliogenesis
|
cell biology
|
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