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Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks
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molecular biology
|
Structural basis for activation of Arf1 at the Golgi complex
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cell biology
|
Thermal acclimation to warmer temperatures can protect host populations from both further heat stress and the potential invasion of pathogens
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ecology
|
Impact of Salmonella genome rearrangement on gene expression
|
genomics
|
Three-dimensional envelope and subunit interactions of the plastid-encoded RNA polymerase from Sinapis alba
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biochemistry
|
Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening
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bioengineering
|
Force Field Dependent DNA Breathing Dynamics: A Case Study of Hoogsteen Base Pairing in A6-DNA
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biophysics
|
The MIX domain is required for T6SS-mediated effector secretion
|
microbiology
|
Polaramycin B, and not physical interaction, is the signal that rewires fungal metabolism in the Streptomyces - Aspergillus interaction.
|
microbiology
|
Physics of Self-Assembly and Morpho-Topological Changes of Klebsiella Pneumoniae in Desiccating Sessile Droplets
|
microbiology
|
A systematic approach to study protein-substrate specificity enables the identification of Ssh1 substrate range
|
cell biology
|
High-throughput single-cell sequencing for retroviral reservoir characterization
|
genomics
|
Cirrhosis and Inflammation Regulates CYP3A4 Mediated Chemoresistance in Vascularized Hepatocellular Carcinoma-on-a-chip
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bioengineering
|
Microbial population dynamics decouple nutrient affinity from environmental concentration
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microbiology
|
Spt6 directly interacts with Cdc73 and is required for Paf1C recruitment to active genes
|
molecular biology
|
Best practice recommendations for sample preservation in metabarcoding studies: a case study on diatom environmental samples
|
molecular biology
|
Elemental content of a host-parasite relationship in the threespine stickleback
|
ecology
|
Global genomic epidemiology, resistome, virulome and plasmidome of the Extraintestinal Pathogenic Escherichia coli (ExPEC) ST38 lineage
|
genomics
|
Thermal adaptation and fatty acid profiles of bone marrow and muscles in mammals: implications of a study of caribou (Rangifer tarandus caribou)
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zoology
|
A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature
|
neuroscience
|
The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease Progression
|
molecular biology
|
The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs
|
molecular biology
|
Expression and functional evaluation of recombinant human ABO blood group antigen cleaving glycoside hydrolases α-N-acetylgalactosaminidase, α-galactosidase, and endo-β-galactosidase produced in Escherichia coli
|
biochemistry
|
AptaMat: a matrix-based algorithm to compare single-stranded oligonucleotides secondary structures
|
bioinformatics
|
Identification of neoantigens in esophageal adenocarcinoma
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cancer biology
|
High-resolution mass spectrometry reveals environmentally relevant uptake, elimination, and metabolic alterations following early embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish
|
pharmacology and toxicology
|
Visualizing cell-cell interactions between immune effector and tumor cells induced by antibodies using a proximity-dependent biosensor system
|
pharmacology and toxicology
|
A computational toolbox to investigate the metabolic potential and resource allocation in fission yeast
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systems biology
|
Morphological evolution and diversity of pectoral fin skeletons in teleosts
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zoology
|
Ribotoxic collisions on CAG expansions disrupt proteostasis and stress responses in Huntington's Disease
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neuroscience
|
Behavioral and brain responses to verbal stimuli reveal transient periods of cognitive integration of external world in all sleep stages
|
neuroscience
|
Perceptual cycles travel across retinotopic space
|
neuroscience
|
Task prioritization modulates low frequency EEG dynamics reflecting proactive cognitive control
|
neuroscience
|
Expression of GDNF Receptors Within Nucleus Ambiguus During Rat Development
|
neuroscience
|
Plasma miRNA-214 is a predictive candidate biomarker of progression speed in patients with ALS
|
neuroscience
|
A pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration
|
neuroscience
|
Retinoic acid-gated BDNF synthesis in neuronal dendrites drives presynaptic homeostatic plasticity
|
neuroscience
|
Multivariate Analysis of PET Pharmacokinetic Parameters
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neuroscience
|
KIF21B binds Myosin Va for Spine Entry and regulates Actin Dynamics to control Homeostatic Synaptic Downscaling
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neuroscience
|
Chronic lymphocytic leukemia includes a tumor subset resembling memory B cells that develop early and persist
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immunology
|
The radio-protective effects of (-)-Epigallocatechin-3-gallate (EGCG): regulating macrophage function in radiation-induced intestinal injury.
|
cell biology
|
Inhibiting 5-lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signaling and insulin-like growth factor-1
|
cell biology
|
An autonomous mathematical model for the mammalian cell cycle
|
cell biology
|
Modelling the spread and mitigation of an emerging vector-borne pathogen:citrus greening in the U.S.
|
ecology
|
Effects of microplastics mixed with natural particles on Daphnia magna populations
|
ecology
|
Genome mining as a biotechnological tool for the discovery of novel biosynthetic genes in lichens
|
genomics
|
Evaluation of Cognitive Function in the Dog Aging Project: Associations with Baseline Canine Characteristics
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animal behavior and cognition
|
Head-direction tracks internally directed selective attention in visual working memory
|
animal behavior and cognition
|
Plasticity facilitates rapid evolution
|
animal behavior and cognition
|
Effects of Body Mass on Leg and Vertical Stiffness in Running Humans
|
bioengineering
|
FAIRsoft - A practical implementation of FAIR principles for research software
|
bioinformatics
|
A dynamical low-rank approach to solve the chemical master equation for biological reaction networks
|
bioinformatics
|
The effect of motor-induced shaft dynamics on microtubule stability and length
|
biophysics
|
Human papilloma virus E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis
|
cancer biology
|
Lipid droplets are a metabolic vulnerability in melanoma
|
cancer biology
|
Hypereosinophilia causes progressive cardiac pathologies in mice
|
pathology
|
Different combinations of laccase paralogs non-redundantly control the lignin amount and composition of specific cell types and cell wall layers in Arabidopsis
|
plant biology
|
Introgression of the Triticum timopheevii genome into wheat detected by chromosome-specific KASP markers
|
plant biology
|
A marked enhancement of a BLOC-1 gene, pallidin, associated with somnolent mouse models deficient in histamine transmission
|
neuroscience
|
The effects of physical and temporal certainty on locomotion with discrete underfoot perturbations
|
neuroscience
|
Katanin is involved in Microtubule Polymerization into Dendritic Spines and regulates Synaptic Plasticity
|
neuroscience
|
Population coding strategies in human tactile afferents
|
neuroscience
|
Actin nano-architecture of phagocytic podosomes
|
cell biology
|
A multiplexed assay of human glucokinase reveals thousands of potential disease variants with both decreased and increased activity
|
genetics
|
Contributions and synaptic basis of diverse cortical neuron responses to task performance
|
neuroscience
|
Airway Basal Cells Show Regionally Distinct Potential to Undergo Metaplastic Differentiation
|
developmental biology
|
A Pairwise Imputation Strategy for Retaining Predictive Features When Combining Multiple Datasets
|
bioinformatics
|
Discovery and characterization of a first-in-field transcription factor BRN2 inhibitor for the treatment of neuroendocrine prostate cancer.
|
cancer biology
|
bi-axial orientation could explain range expansion in a migratory songbird
|
zoology
|
Group A streptococci induce high-affinity M protein-fibronectin interaction when specific human antibodies are bound
|
immunology
|
Population Genomics of Stone Age Eurasia
|
evolutionary biology
|
BREEDIT: A novel multiplex genome editing strategy to improve complex quantitative traits in maize (Zea mays L.)
|
systems biology
|
Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development
|
microbiology
|
Online Bayesian Analysis with BEAST 2
|
bioinformatics
|
Human collision avoidance behavior against autonomous mobile robot
|
neuroscience
|
Responses of Model Cortical Neurons to Temporal Interference Stimulation and Other Transcranial Alternating Current Stimulation Modalities
|
bioengineering
|
Involvement of Lateral Habenula Dysfunction in Repetitive Mild Traumatic Brain Injury-Induced Motivational Deficits
|
neuroscience
|
Early structural connectivity within the sensorimotor network: deviations related to prematurity and association to neurodevelopmental outcome
|
neuroscience
|
Paired stimulation for spike-timing dependent plasticity quantified with single neuron responses in primate motor cortex
|
neuroscience
|
Curation of BIDS (CuBIDS): a workflow and software package for streamlining reproducible curation of large BIDS datasets
|
neuroscience
|
Common genetic variants in CHRNA5 alter β-amyloid neuropathology and highlight chandelier cells in human aging and Alzheimer's disease
|
neuroscience
|
Neural correlates for neonicotinoid-induced impairment of olfactory long-term memory
|
neuroscience
|
A comprehensive analysis of Usutu virus (USUV) genomes revealed lineage-specific codon usage patterns and host adaptation
|
microbiology
|
Development of dim-light vision in the nocturnal coral reef fish family, Holocentridae
|
developmental biology
|
Groundfish biodiversity change in northeast Pacific waters under projected warming and deoxygenation
|
ecology
|
Identifying disease-associated circRNAs based on edge-weighted graph attention and heterogeneous graph neural network
|
bioinformatics
|
Biological age is increased by stress and restored upon recovery
|
systems biology
|
Microglial expression of the Wnt signalling modulator DKK2 differs between human Alzheimer's disease brains and mouse neurodegeneration models
|
neuroscience
|
A parallel channel of state-dependent sensory signaling from the cholinergic basal forebrain to the auditory cortex
|
neuroscience
|
Novel Computational Models of Evoked Dopamine Release In Vivo Measured by Fast Scan Cyclic Voltammetry Quantify the Regulation of Presynaptic Kinetics by Synucleins
|
neuroscience
|
Early patterning followed by tissue growth establishes proximo-distal identity in Drosophila Malpighian tubules
|
developmental biology
|
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis
|
biochemistry
|
Molecular basis of C9orf72 poly-PR interference with the β-karyopherin family of nuclear transport receptors
|
biophysics
|
Structure of the lysosomal membrane fusion machinery
|
biophysics
|
Dual-wavelength stopped-flow analysis of the lateral and longitudinal assembly kinetics of vimentin
|
biophysics
|
Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi
|
microbiology
|
Hemodynamic stress activates inflammatory responses and cell death through spectrin-dependent modulation of Store Operated Calcium Entry
|
cell biology
|
Gene family expansion and functional diversification of chitinase and chitin synthase genes in Atlantic salmon (Salmo salar)
|
genetics
|
The role of dynamic DNA methylation in liver transplant rejection in children
|
genomics
|
Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation
|
biochemistry
|
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