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Two Competing Guilds as a Core Microbiome Signature for Chronic Diseases
|
microbiology
|
In situ structural analysis reveals membrane shape transitions during autophagosome formation
|
cell biology
|
Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage
|
evolutionary biology
|
Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment
|
cancer biology
|
Context-dependent effects explain divergent prognostic roles of Tregs in cancer
|
cancer biology
|
A Phytophthora nucleolar effector, Pi23226, targets to host ribosome biogenesis for necrotrophic cell death
|
plant biology
|
Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance
|
synthetic biology
|
Selection of Single Domain Anti-Transferrin Receptor Antibodies for Blood-Brain Barrier Transcytosis Using a Neurotensin Based Assay and Histological Assessment of Target Engagement in a Mouse Model of Alzheimer's Disease-Related Amyloid-Beta Pathology
|
neuroscience
|
A resource for generating and manipulating human microglial states in vitro
|
neuroscience
|
Inner hair cell synapse density influences auditory processing
|
neuroscience
|
Quantitative stable-isotope probing (qSIP) with metagenomics links microbial physiology and activity to soil moisture in Mediterranean-climate grassland ecosystems
|
microbiology
|
ATP induced conformational change of axonemal outer dynein arms studied by cryo-electron tomography
|
molecular biology
|
Extreme tolerable winds for seabirds are determined by morphology
|
animal behavior and cognition
|
Scalable sequence-informed embedding of single-cell ATAC-seq data with CellSpace
|
bioinformatics
|
A new species of deepwater Lethrinops (Cichlidae) from Lake Malawi
|
zoology
|
EGR2 promoter antisense RNA coordinates chromatin remodeling and spatial genome organization in Schwann cells.
|
neuroscience
|
Perchlorate-Specific Proteomic Stress Responses of Debaryomyces hansenii Could Enable Microbial Survival in Martian Brines
|
cell biology
|
Insight into RNA-DNA primer length counting by human primosome
|
biochemistry
|
Highly dense and scalable protein arrays for single-molecule studies
|
bioengineering
|
Convergence on reduced aggression through shared behavioral traits in multiple populations of Astyanax mexicanus
|
evolutionary biology
|
The swan genome and transcriptome: its not all black and white
|
genomics
|
Modeling the kinetics of amyloid beta pores and long-term evolution of their Ca2+ toxicity
|
cell biology
|
Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2
|
genomics
|
Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine
|
biochemistry
|
TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity
|
plant biology
|
Deep multi-omic network fusion for marker discovery of Alzheimer's Disease
|
systems biology
|
Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
|
cell biology
|
Puberty contributes to adolescent development of fronto-striatal functional connectivity supporting inhibitory control
|
neuroscience
|
CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
|
neuroscience
|
Axl contributes to efficient migration and invasion of melanoma cells
|
cell biology
|
Deeply conserved super-enhancers maintain stem cell pluripotency in placental mammals
|
cell biology
|
Pallidin function in drosophila surface glia regulates sleep and is dependent on amino acid availability
|
neuroscience
|
Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the nucleus accumbens
|
neuroscience
|
Chromosomal inversions can limit adaptation to new environments
|
evolutionary biology
|
Chromosome-level Genomes Reveal the Genetic Basis of Descending Dysploidy and Sex Determination in Morus Plants
|
genomics
|
Arc-Expressing Accessory Olfactory Bulb Interneurons Support Chemosensory Social Behavioral Plasticity
|
neuroscience
|
Protection from Omicron and other VOCs by Bivalent S-Trimer COVID-19 Vaccine
|
immunology
|
Spatiotemporal landscape of SARS-CoV-2 pulmonary infection reveals Slamf9+Spp1+ macrophages promoting viral clearance and inflammation resolution
|
immunology
|
Sensitivity of novel SARS-CoV-2 Omicron subvariants, BA.2.11, BA.2.12.1, BA.4 and BA.5 to therapeutic monoclonal antibodies
|
microbiology
|
Dietary derived Vitamin B12 protects the nematode Caenorhabditis elegans from thiol reducing agents.
|
biochemistry
|
Critical Mechanistic Role of Inositol Hexakisphosphate (IP6) in HIV-1 Viral Capsid Assembly
|
biophysics
|
Actuating tension-loaded DNA clamps drives membrane tubulation
|
synthetic biology
|
FoxP3-mediated blockage of ryanodine receptor 2 is the molecular basis for the contact-based suppression by regulatory T cells
|
immunology
|
The making of the oral microbiome in Agta hunter-gatherers
|
microbiology
|
Hunter-gatherer oral microbiomes are shaped by contact network structure
|
microbiology
|
Carbapenem heteroresistance of KPC-producing Klebsiella pneumoniae results from tolerance, persistence and resistance.
|
microbiology
|
The dually localized EF-hand domain-containing protein TgEFP1 regulates the lytic cycle of Toxoplasma gondii
|
microbiology
|
Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance
|
microbiology
|
Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acids
|
microbiology
|
Viruses inhibit TIR gcADPR signaling to overcome bacterial defense
|
microbiology
|
High-efficiency HDR in immortalized cell lines by crude rAAV mediated donor template delivery
|
molecular biology
|
Semi-field evaluation of the space spray efficacy of Fludora Co-Max EW against wild insecticide-resistant Aedes aegypti and Culex quinquefasciatus mosquito populations from Abidjan, Cote d'Ivoire
|
ecology
|
Profiling RNA at chromatin targets in situ by antibody-targeted tagmentation
|
genomics
|
Thousands of human non-AUG extended proteoforms lack evidence of evolutionary selection among mammals
|
genomics
|
HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation
|
biochemistry
|
Variations of a theme - crystal forms of the amino acid transporter MhsT
|
biochemistry
|
Nuclear receptor ligand screening in an iPSC-derived in vitro blood-brain barrier model identifies new contributors to leptin transport
|
neuroscience
|
Bacterial Infection of the Placenta Induces Sex-Specific Responses in the Fetal Brain
|
microbiology
|
Endogenous sterol synthesis is dispensable for Trypanosoma cruzi epimastigote growth but not stress tolerance
|
microbiology
|
Cell detoxification of secondary metabolites by P4-ATPase mediated vesicle transport
|
microbiology
|
The contribution of Kaposis sarcoma-associated herpesvirus ORF7 and its zinc-finger motif to viral genome cleavage and capsid formation
|
microbiology
|
The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis
|
molecular biology
|
One-Step Making of DNA Dumbbells Allows Tunneling of Short-Read Libraries into a Long-Read Format
|
molecular biology
|
Defective subviral particles modify ecological equilibria and enhance viral coexistence
|
ecology
|
Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
|
biochemistry
|
A molecular plugin rescues GroEL/ES substrates from pre-folding oxidation
|
biochemistry
|
Describing Inhibitor Specificity for the Amino Acid Transporter LAT1 from Metainference Simulations
|
biophysics
|
A transcriptional cycling model recapitulates chromatin-dependent features of noisy inducible transcription
|
systems biology
|
An in-vitro investigation of effects of acetylcholine on attenuate and low motile diluted rooster semen quality
|
cell biology
|
Selection and validation of reference genes for quantitative real-time polymerase chain reaction in Serratia ureilytica DW2
|
microbiology
|
Sensory responses in dorsolateral striatum are modulated by motor activity in a dopamine-dependent manner
|
neuroscience
|
Robust associations between white matter microstructure and general intelligence
|
neuroscience
|
Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
|
developmental biology
|
Extrinsic regulation of interneuron specification and migration
|
developmental biology
|
Regulation of translation by lysine acetylation in Escherichia coli
|
microbiology
|
Helminth egg derivatives as pro-regenerative immunotherapies
|
bioengineering
|
A common framework for discriminability and perceived intensity of sensory stimuli
|
neuroscience
|
Identification of key molecules and biological processes in TCF21 treated tumor pericytes
|
bioinformatics
|
Taxonbridge: an R package to create custom taxonomies based on the NCBI and GBIF taxonomies
|
bioinformatics
|
PathGPS: Discover shared genetic architecture using biobank data
|
bioinformatics
|
H3AGWAS : A portable workflow for Genome Wide Association Studies
|
bioinformatics
|
Computer simulations reveal pathogenicity and inheritance modes of hearing loss-causing germinal variants
|
biophysics
|
IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits
|
physiology
|
A transcriptional complex of FtMYB102 and FtbHLH4 coordinately regulates the accumulation of rutin in Fagopyrum tataricum
|
plant biology
|
Multi-omics analyses of drug repurposing reveal Acebutolol and Amiloride for osteoporosis treatment
|
systems biology
|
KINOMO: A non-negative matrix factorization framework for recovering intra- and inter-tumoral heterogeneity from single-cell RNA-seq data
|
systems biology
|
Motor and Visual Plasticity Interact in Adult Humans
|
neuroscience
|
A neural mechanism for terminating decisions
|
neuroscience
|
Independent spatiotemporal effects of spatial attention and background clutter on human object location representations
|
neuroscience
|
The passive representations were consciously formed via the representational transition from the active state
|
neuroscience
|
Auditory spatial analysis in reverberant audio-visual multi-talker environments with congruent and incongruent visual room information
|
neuroscience
|
ISG15 Monomer Promotes IFNα-mediated Antiviral Activity against Pseudorabies Virus by Facilitating phosphorylation of STAT1/STAT2
|
molecular biology
|
Gene expression analysis of the Xenopus laevis early limb bud proximodistal axis.
|
developmental biology
|
Ability of the Ash dieback pathogen to reproduce and to induce damage on its host are controlled by different environmental parameters
|
ecology
|
Abrupt transitions and its indicators in mutualistic meta-networks: effects of network topology, size of metacommunities and species dispersal
|
ecology
|
An improved species richness estimator using spatial abundance data
|
ecology
|
The role of geology in creating stream climate-change refugia along climate gradients
|
ecology
|
Validation of the Tea Bag Index as a standard approach for assessing organic matter decomposition
|
ecology
|
Defining marine bacterioplankton community assembly rules by contrasting the importance of environmental determinants and biotic interactions
|
ecology
|
DNAJC13 influences responses of the extended reward system to conditioned stimuli: a genome-wide association study
|
genomics
|
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